|
Name |
Accession |
Description |
Interval |
E-value |
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-305 |
0e+00 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 502.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:COG1125 1 MIEFENVTKRYpDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVELRRRIGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVN-LRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:COG1125 81 VIQQIGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLDPEeYRDRYPHELSGGQQQRVGVARALAADPPILLM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 159 DEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGRS 238
Cdd:COG1125 161 DEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVGAD 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 239 ElGVRLLSLRSVGDYVRRHEQVggdaLAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL 305
Cdd:COG1125 241 R-GLRRLSLLRVEDLMLPEPPT----VSPDASLREALSLMLERGVDWLLVVDEDGRPLGWLTLEDLL 302
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-241 |
4.11e-149 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 418.24 E-value: 4.11e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGA-QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:cd03295 1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLD-VNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:cd03295 81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 160 EPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGRSE 239
Cdd:cd03295 161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVGADR 240
|
..
gi 581977852 240 LG 241
Cdd:cd03295 241 LL 242
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
9-292 |
4.97e-96 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 288.29 E-value: 4.97e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 9 KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL----RRRMGYAIQSI 84
Cdd:TIGR01186 1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPVELrevrRKKIGMVFQQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 GLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGA 164
Cdd:TIGR01186 81 ALFPHMTILQNTSLGPELLGWPEQERKEKALELLKLVGLE-EYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 165 LDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGrselGVRL 244
Cdd:TIGR01186 160 LDPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIG----KVDL 235
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 581977852 245 LSLRSVGDYVRRHEQVGGDALAEEmTLRDALSVFVARGCDVLPVVDQQ 292
Cdd:TIGR01186 236 SQVFDAERIAQRMNTGPITKTADK-GPRSALQLMRDERVDSLYVVDRQ 282
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-238 |
8.33e-96 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 286.99 E-value: 8.33e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlElRRRMGYA 80
Cdd:COG3842 5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPP-E-KRNVGMV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:COG3842 83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLE-GLADRYPHQLSGGQQQRVALARALAPEPRVLLLDE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGRS 238
Cdd:COG3842 162 PLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-296 |
5.74e-89 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 269.71 E-value: 5.74e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRS-LPVLElrRRMGYA 80
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTnLPPRE--RRVGFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:COG1118 81 FQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLE-GLADRYPSQLSGGQRQRVALARALAVEPEVLLLDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGrsel 240
Cdd:COG1118 160 PFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLG---- 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 241 gvrlLSLRSVGDYVRRHEQVGGDALAEEMTLRDALSVFVARGCDVLPVVDQQGTPC 296
Cdd:COG1118 236 ----CVNVLRGRVIGGQLEADGLTLPVAEPLPDGPAVAGVRPHDIEVSREPEGENT 287
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-315 |
6.40e-89 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 270.82 E-value: 6.40e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQK------------------------AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSG 56
Cdd:COG4175 3 KIEVRNLYKIFGKRPeralklldqgkskdeilektgqtvGVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 57 VIRFAGEEIRSLPVLEL----RRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYP 132
Cdd:COG4175 83 EVLIDGEDITKLSKKELrelrRKKMSMVFQHFALLPHRTVLENVAFGLEIQGVPKAERRERAREALELVGLA-GWEDSYP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 133 HQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGE 212
Cdd:COG4175 162 DELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREMQDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 213 VVQQGTPLEMLTAPANDFVQAFFGrselGVRLLSLRSVGDYVRRHEQVggdaLAEEMTLRDALSVFVARGCDVLPVVDQQ 292
Cdd:COG4175 242 IVQIGTPEEILTNPANDYVADFVE----DVDRSKVLTAGSVMRPPEAV----VSEKDGPRVALRRMREEGISSLYVVDRD 313
|
330 340
....*....|....*....|...
gi 581977852 293 GTPCGTLHfRDLLSEALPGETTV 315
Cdd:COG4175 314 RRLLGVVT-ADDALEAVKGEKDL 335
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-236 |
9.05e-85 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 258.85 E-value: 9.05e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYA 80
Cdd:COG3839 3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD--RNIAMV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:COG3839 81 FQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLE-DLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDE 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:COG3839 160 PLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIG 235
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
7-235 |
3.99e-84 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 254.49 E-value: 3.99e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRR-RMGYAIQ 82
Cdd:cd03294 30 ILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSrkeLRELRRkKISMVFQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 SIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPF 162
Cdd:cd03294 110 SFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLE-GWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAF 188
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 163 GALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFF 235
Cdd:cd03294 189 SALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFF 261
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-217 |
2.73e-83 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 250.13 E-value: 2.73e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLelRRRMGYAI 81
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE--RRNIGMVF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03259 79 QDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLE-GLLNRYPHELSGGQQQRVALARALAREPSLLLLDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03259 158 LSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-211 |
1.32e-82 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 250.01 E-value: 1.32e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF----GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEeirslPVLELRRR 76
Cdd:COG1116 7 ALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGK-----PVTGPGPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG1116 82 RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLA-GFEDAYPHQLSGGMRQRVAIARALANDPEVL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGG 211
Cdd:COG1116 161 LMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSAR 215
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-236 |
2.72e-80 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 243.30 E-value: 2.72e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLelRRRMGYAI 81
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPH--KRPVNTVF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03300 79 QNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLE-GYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEP 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:cd03300 158 LGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-210 |
2.77e-79 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 240.45 E-value: 2.77e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG----AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEeirslPVLELRRRM 77
Cdd:cd03293 1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGE-----PVTGPGPDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:cd03293 76 GYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLS-GFENAYPHQLSGGMRQRVALARALAVDPDVLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDG 210
Cdd:cd03293 155 LDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSA 207
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-237 |
9.20e-77 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 234.50 E-value: 9.20e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLPVLELRRRMG 78
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLtdSKKDINKLRRKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:COG1126 81 MVFQQFNLFPHLTVLENVTLAPiKVKKMSKAEAEERAMELLERVGLA-DKADAYPAQLSGGQQQRVAIARALAMEPKVML 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 158 MDEPFGALDPvtrgalqqEMTR-----IHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDF 230
Cdd:COG1126 160 FDEPTSALDP--------ELVGevldvMRDLakEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHER 231
|
....*..
gi 581977852 231 VQAFFGR 237
Cdd:COG1126 232 TRAFLSK 238
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-235 |
2.97e-75 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 230.64 E-value: 2.97e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPV---LELRRRM 77
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEkelYELRRRI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNIAtVP--QLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:COG1127 85 GMLFQGGALFDSLTVFENVA-FPlrEHTDLSEAEIRELVLEKLELVGLP-GAADKMPSELSGGMRKRVALARALALDPEI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPaNDFVQAFF 235
Cdd:COG1127 163 LLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLASD-DPWVRQFL 241
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-236 |
2.17e-72 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 223.37 E-value: 2.17e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYAI 81
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE--RNVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIA----TVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:cd03296 81 QHYALFRHMTVFDNVAfglrVKPRSERPPEAEIRAKVHELLKLVQLD-WLADRYPAQLSGGQRQRVALARALAVEPKVLL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:cd03296 160 LDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLG 238
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-236 |
2.62e-70 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 221.49 E-value: 2.62e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF----GAQKAVNDLNLHFREGS-FSVlIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL-- 73
Cdd:COG1135 1 MIELENLSKTFptkgGPVTALDDVSLTIEKGEiFGI-IGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELra 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 -RRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAAD 152
Cdd:COG1135 80 aRRKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLS-DKADAYPSQLSGGQKQRVGIARALANN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQ 232
Cdd:COG1135 159 PKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSELTR 238
|
....
gi 581977852 233 AFFG 236
Cdd:COG1135 239 RFLP 242
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-223 |
2.27e-69 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 215.70 E-value: 2.27e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAI 81
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPA-EVRRRIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:COG1131 80 QEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLT-DAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 162 FGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:COG1131 159 TSGLDPEARRELWELLRELAA-EGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK 219
|
|
| 3a0106s01 |
TIGR00968 |
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions] |
2-236 |
1.35e-68 |
|
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 213.89 E-value: 1.35e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLelRRRMGYAI 81
Cdd:TIGR00968 1 IEIANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHAR--DRKIGFVF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:TIGR00968 79 QHYALFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLE-GLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEP 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:TIGR00968 158 FGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLG 232
|
|
| tungstate_WtpC |
NF040840 |
tungstate ABC transporter ATP-binding protein WtpC; |
1-236 |
1.81e-68 |
|
tungstate ABC transporter ATP-binding protein WtpC;
Pssm-ID: 468779 [Multi-domain] Cd Length: 347 Bit Score: 217.25 E-value: 1.81e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKaVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvLElRRRMGYA 80
Cdd:NF040840 1 MIRIENLSKDWKEFK-LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLP-PE-KRGIAYV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:NF040840 78 YQNYMLFPHKTVFENIAFGLKLRKVPKEEIERKVKEIMELLGIS-HLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDE 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:NF040840 157 PLSALDVQTRDELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVG 232
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
6-237 |
4.49e-68 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 216.06 E-value: 4.49e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 6 HVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLelRRRMGYAIQSIG 85
Cdd:TIGR03265 9 NIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQ--KRDYGIVFQSYA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 86 LFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGAL 165
Cdd:TIGR03265 87 LFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLP-GSERKYPGQLSGGQQQRVALARALATSPGLLLLDEPLSAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 166 DPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGR 237
Cdd:TIGR03265 166 DARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGE 237
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-233 |
7.62e-68 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 220.16 E-value: 7.62e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-----GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLE 72
Cdd:COG1123 260 LLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSrrsLRE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQ----SigLFPHWTVAQNIATVPQLQKW-SRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVAR 147
Cdd:COG1123 340 LRRRVQMVFQdpysS--LNPRMTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLPPDLADRYPHELSGGQRQRVAIAR 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:COG1123 418 ALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQ 497
|
....*.
gi 581977852 228 NDFVQA 233
Cdd:COG1123 498 HPYTRA 503
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-234 |
3.50e-67 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 210.05 E-value: 3.50e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL---RRRMG 78
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELyrlRRRMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHWTVAQNIAtVPQLQ--KWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:cd03261 81 MLFQSGALFDSLTVFENVA-FPLREhtRLSEEEIREIVLEKLEAVGLR-GAEDLYPAELSGGMKKRVALARALALDPELL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPaNDFVQAF 234
Cdd:cd03261 159 LYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRASD-DPLVRQF 235
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-217 |
8.88e-67 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 208.26 E-value: 8.88e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYAI 81
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD--RDIAMVF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03301 79 QNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIE-HLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03301 158 LSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-226 |
1.78e-66 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 208.20 E-value: 1.78e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQ----KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL--- 73
Cdd:cd03258 1 MIELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELrka 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADP 153
Cdd:cd03258 81 RRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLE-DKADAYPAQLSGGQKQRVGIARALANNP 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 154 QVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:cd03258 160 KVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANP 232
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-226 |
2.45e-66 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 207.57 E-value: 2.45e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQS--IGLF-PhwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:COG1122 81 FQNpdDQLFaP--TVEEDVAFGPENLGLPREEIRERVEEALELVGLE-HLADRPPHELSGGQKQRVAIAGVLAMEPEVLV 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:COG1122 158 LDEPTAGLDPRGRRELLELLKRLNK-EGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-212 |
9.28e-66 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 204.34 E-value: 9.28e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSL--PVLELRRRMGY 79
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLedELPPLRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIAtvpqlqkwsrsriddrteelmallgldvnlrhrypHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:cd03229 81 VFQDFALFPHLTVLENIA-----------------------------------LGLSGGQQQRVALARALAMDPDVLLLD 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 581977852 160 EPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGE 212
Cdd:cd03229 126 EPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
19-236 |
1.49e-65 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 206.03 E-value: 1.49e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlELRRRMGYAIQSIGLFPHWTVAQNIAT 98
Cdd:cd03299 17 NVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLP--PEKRDISYVPQNYALFPHMTVYKNIAY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 VPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMT 178
Cdd:cd03299 95 GLKKRKVDKKEIERKVLEIAEMLGID-HLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELK 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 179 RIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:cd03299 174 KIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLG 231
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-216 |
3.30e-65 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 204.51 E-value: 3.30e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFG----AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL--- 73
Cdd:COG1136 4 LLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELarl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 -RRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAAD 152
Cdd:COG1136 84 rRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLG-DRLDHRPSQLSGGQQQRVAIARALVNR 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDiDEALRLAEHLVLMDGGEVVQQ 216
Cdd:COG1136 163 PKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGRIVSD 225
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-213 |
2.84e-64 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 201.60 E-value: 2.84e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLPVLELRRRMGY 79
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLtdDKKNINELRQKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:cd03262 81 VFQQFNLFPHLTVLENITLAPiKVKGMSKAEAEERALELLEKVGLA-DKADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 159 DEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:cd03262 160 DEPTSALDPELVGEVLDVMKDLAE-EGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-214 |
1.10e-63 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 200.66 E-value: 1.10e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRR 76
Cdd:COG2884 1 MIRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKrreIPYLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG2884 81 IGVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLS-DKAKALPHELSGGEQQRVAIARALVNRPELL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:COG2884 160 LADEPTGNLDPETSWEIMELLEEINR-RGTTVLIATHDLELVDRMPKRVLELEDGRLV 216
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-236 |
3.32e-63 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 204.41 E-value: 3.32e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLelRRRMGYAI 81
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAE--NRHVNTVF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:PRK09452 93 QSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLE-EFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDES 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:PRK09452 172 LSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIG 246
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-225 |
1.55e-62 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 198.73 E-value: 1.55e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIAT--VPQLQKWSRSRIDDRT--EELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG1120 81 PQEPPAPFGLTVRELVALgrYPHLGLFGRPSAEDREavEEALERTGLE-HLADRPVDELSGGERQRVLIARALAQEPPLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:COG1120 160 LLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTP 228
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-234 |
2.53e-62 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 201.18 E-value: 2.53e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQK----AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRr 76
Cdd:PRK11153 1 MIELKNISKVFPQGGrtihALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRK- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 mgyAIQSIGL-FPHW------TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARAL 149
Cdd:PRK11153 80 ---ARRQIGMiFQHFnllssrTVFDNVALPLELAGTPKAEIKARVTELLELVGLS-DKADRYPAQLSGGQKQRVAIARAL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 150 AADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAND 229
Cdd:PRK11153 156 ASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHP 235
|
....*
gi 581977852 230 FVQAF 234
Cdd:PRK11153 236 LTREF 240
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-236 |
4.42e-62 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 200.70 E-value: 4.42e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYAI 81
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD--RKVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIA---TV-PQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK10851 81 QHYALFRHMTVFDNIAfglTVlPRRERPNAAAIKAKVTQLLEMVQLA-HLADRYPAQLSGGQKQRVALARALAVEPQILL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:PRK10851 160 LDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMG 238
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-213 |
7.77e-62 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 195.79 E-value: 7.77e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK----AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL---- 73
Cdd:cd03255 1 IELKNLSKTYGGGGekvqALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELaafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADP 153
Cdd:cd03255 81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLG-DRLNHYPSELSGGQQQRVAIARALANDP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 154 QVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEAlRLAEHLVLMDGGEV 213
Cdd:cd03255 160 KIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGKI 218
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-240 |
1.08e-61 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 196.23 E-value: 1.08e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvLELRRRMGYA 80
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEP-REARRQIGVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:COG4555 80 PDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLE-EFLDRRVGELSTGMKKKVALARALVHDPKVLLLDE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 161 PFGALDPVTRGALQQEMTRiHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAND-----FVQAFF 235
Cdd:COG4555 159 PTNGLDVMARRLLREILRA-LKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEEnledaFVALIG 237
|
....*
gi 581977852 236 GRSEL 240
Cdd:COG4555 238 SEEGE 242
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-239 |
2.09e-60 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 193.10 E-value: 2.09e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGA----QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR 76
Cdd:COG1124 1 MLEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIG--LFPHWTVAQNIATVPQLQKwsRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:COG1124 81 VQMVFQDPYasLHPRHTVDRILAEPLRIHG--LPDREERIAELLEQVGLPPSFLDRYPHQLSGGQRQRVAIARALILEPE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 155 VLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAF 234
Cdd:COG1124 159 LLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKHPYTREL 238
|
....*
gi 581977852 235 FGRSE 239
Cdd:COG1124 239 LAASL 243
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-217 |
1.24e-59 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 190.41 E-value: 1.24e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF----GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvLELRRR 76
Cdd:cd03257 1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS-RRLRKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIG------LFPHWTVAQNIATVPQLQK--WSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARA 148
Cdd:cd03257 80 RRKEIQMVFqdpmssLNPRMTIGEQIAEPLRIHGklSKKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQRVAIARA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03257 160 LALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
32-268 |
1.58e-59 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 193.48 E-value: 1.58e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 32 LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlELRRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRID 111
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVP--PHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 112 DRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLV 191
Cdd:TIGR01187 79 PRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFV 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 192 THDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGRSELgVRLLSLRSVGDYVRRHEQVGGDALAEE 268
Cdd:TIGR01187 158 THDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINV-FEATVIERKSEQVVLAGVEGRRCDIYT 233
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-234 |
1.95e-59 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 190.30 E-value: 1.95e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR--SLPVLELRRRMG 78
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpKVDERLIRQEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDVNLRHrYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK09493 81 MVFQQFYLFPHLTALENVMFGPlRVRGASKEEAEKQARELLAKVGLAERAHH-YPSELSGGQQQRVAIARALAVKPKLML 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 158 MDEPFGALDPvtrgALQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAF 234
Cdd:PRK09493 160 FDEPTSALDP----ELRHEVLKVMQDLaeeGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEF 235
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-221 |
2.45e-58 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 188.81 E-value: 2.45e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGA-----QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRS---LPVLEL 73
Cdd:TIGR04521 1 IKLKNVSYIYQPgtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAkkkKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARA 148
Cdd:TIGR04521 81 RKKVGLVFQ----FPEHqlfeeTVYKDIAFGPKNLGLSEEEAEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGV 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLE 221
Cdd:TIGR04521 157 LAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPRE 229
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-227 |
1.11e-57 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 193.58 E-value: 1.11e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD---SGVIRFAGEEIRSLPVLELRR 75
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRGR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQSIG--LFPhWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADP 153
Cdd:COG1123 84 RIGMVFQDPMtqLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLE-RRLDRYPHQLSGGQRQRVAIAMALALDP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 154 QVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:COG1123 162 DLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQ 235
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
3-212 |
1.19e-57 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 184.59 E-value: 1.19e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 3 EFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:cd03225 1 ELKNLSFSYpdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:cd03225 81 FQ----NPDDqffgpTVEEEVAFGLENLGLPEEEIEERVEEALELVGLE-GLRDRSPFTLSGGQKQRVAIAGVLAMDPDI 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGE 212
Cdd:cd03225 156 LLLDEPTAGLDPAGRRELLELLKKLKA-EGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-219 |
1.48e-56 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 182.38 E-value: 1.48e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEH-----DSGVIRFAGEEIRSL--PVLELR 74
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLdvDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 RRMGYAIQSIGLFPHwTVAQNIATVPQLQ-KWSRSRIDDRTEELMALLGLDVNL-RHRYPHQLSGGQQQRVGVARALAAD 152
Cdd:cd03260 81 RRVGMVFQKPNPFPG-SIYDNVAYGLRLHgIKLKEELDERVEEALRKAALWDEVkDRLHALGLSGGQQQRLCLARALANE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTP 219
Cdd:cd03260 160 PEVLLLDEPTSALDPISTAKIEELIAELKK--EYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPT 224
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
7-236 |
2.07e-55 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 184.08 E-value: 2.07e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYAIQSIGL 86
Cdd:PRK11000 9 VTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE--RGVGMVFQSYAL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 87 FPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALD 166
Cdd:PRK11000 87 YPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLA-HLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLD 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 167 PVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:PRK11000 166 AALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIG 235
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
19-244 |
8.59e-55 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 181.84 E-value: 8.59e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGE------EIRSLPVLelRRRMGYAIQSIGLFPHWTV 92
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEvlqdsaRGIFLPPH--RRRIGYVFQEARLFPHLSV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 93 AQNIatvpqLQKWSRSRIDDRT---EELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVT 169
Cdd:COG4148 95 RGNL-----LYGRKRAPRAERRisfDEVVELLGIG-HLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLAR 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 170 RGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAndfVQAFFGRSELGVRL 244
Cdd:COG4148 169 KAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPD---LLPLAGGEEAGSVL 240
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-239 |
2.40e-54 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 177.56 E-value: 2.40e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRR 76
Cdd:COG3638 2 MLELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRgraLRRLRRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNI-----ATVPQLQKWSRS-RIDDRTEELMAL--LGLDVNLRHRyPHQLSGGQQQRVGVARA 148
Cdd:COG3638 82 IGMIFQQFNLVPRLSVLTNVlagrlGRTSTWRSLLGLfPPEDRERALEALerVGLADKAYQR-ADQLSGGQQQRVAIARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPlEMLTApan 228
Cdd:COG3638 161 LVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPP-AELTD--- 236
|
250
....*....|.
gi 581977852 229 DFVQAFFGRSE 239
Cdd:COG3638 237 AVLREIYGGEA 247
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-213 |
1.12e-53 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 173.35 E-value: 1.12e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAI 81
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPE-EVKRRIGYLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIatvpqlqkwsrsriddrteelmallgldvnlrhryphQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03230 80 EEPSLYENLTVRENL-------------------------------------KLSGGMKQRLALAQALLHDPELLILDEP 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 162 FGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:cd03230 123 TSGLDPESRREFWELLRELKK-EGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-211 |
1.23e-53 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 176.21 E-value: 1.23e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFG----AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlPVLElrrr 76
Cdd:COG4525 3 MLTVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-PGAD---- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG4525 78 RGVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLA-DFARRRIWQLSGGMRQRVGIARALAADPRFL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGG 211
Cdd:COG4525 157 LMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMSPG 211
|
|
| PhnT |
TIGR03258 |
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ... |
2-240 |
1.76e-53 |
|
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.
Pssm-ID: 132302 [Multi-domain] Cd Length: 362 Bit Score: 179.03 E-value: 1.76e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD--SGVIRFAGEEIRSLPvlELRRRMGY 79
Cdd:TIGR03258 6 IRIDHLRVAYGANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAglTGRIAIADRDLTHAP--PHKRGLAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:TIGR03258 84 LFQNYALFPHLKVEDNVAFGLRAQKMPKADIAERVADALKLVGLG-DAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 160 EPFGALDPVTRGALQQEMTRIHRLLGR-TIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGRS 238
Cdd:TIGR03258 163 EPLSALDANIRANMREEIAALHEELPElTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGAA 242
|
..
gi 581977852 239 EL 240
Cdd:TIGR03258 243 NI 244
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-236 |
2.59e-53 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 178.88 E-value: 2.59e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlELRRRMGYA 80
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVP--PYQRPINMM 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:PRK11607 97 FQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQ-EFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:PRK11607 176 PMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIG 251
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-239 |
4.29e-53 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 174.46 E-value: 4.29e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGY 79
Cdd:COG0411 4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARLgIAR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQ---------------KWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVG 144
Cdd:COG0411 84 TFQNPRLFPELTVLENVLVAAHARlgrgllaallrlpraRREEREARERAEELLERVGLA-DRADEPAGNLSYGQQRRLE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 145 VARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:COG0411 163 IARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVRA 242
|
250
....*....|....*.
gi 581977852 225 APAndfVQ-AFFGRSE 239
Cdd:COG0411 243 DPR---VIeAYLGEEA 255
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-227 |
5.57e-53 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 173.91 E-value: 5.57e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK-AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL---RRRM 77
Cdd:cd03256 1 IEVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALrqlRRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNI-----ATVPQLqkWSRSRIDDRTEELMALLGLD-VNLRHRY---PHQLSGGQQQRVGVARA 148
Cdd:cd03256 81 GMIFQQFNLIERLSVLENVlsgrlGRRSTW--RSLFGLFPKEEKQRALAALErVGLLDKAyqrADQLSGGQQQRVAIARA 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPlEMLTAPA 227
Cdd:cd03256 159 LMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPP-AELTDEV 236
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
12-256 |
8.18e-53 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 178.30 E-value: 8.18e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELR----RRMGYAIQSIGLF 87
Cdd:PRK10070 39 GLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRevrrKKIAMVFQSFALM 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 88 PHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDP 167
Cdd:PRK10070 119 PHMTVLDNTAFGMELAGINAEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDP 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 168 VTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFgrseLGVRLLSL 247
Cdd:PRK10070 198 LIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFF----RGVDISQV 273
|
....*....
gi 581977852 248 RSVGDYVRR 256
Cdd:PRK10070 274 FSAKDIARR 282
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
19-217 |
1.02e-52 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 172.09 E-value: 1.02e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFR-EGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAG------EEIRSLPVLelRRRMGYAIQSIGLFPHWT 91
Cdd:cd03297 14 TLKIDFDlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGtvlfdsRKKINLPPQ--QRKIGLVFQQYALFPHLN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 92 VAQNIATVpqLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRG 171
Cdd:cd03297 92 VRENLAFG--LKRKRNREDRISVDELLDLLGLD-HLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 581977852 172 ALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03297 169 QLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
9-234 |
1.46e-52 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 173.06 E-value: 1.46e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 9 KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP-------------VLELRR 75
Cdd:COG4598 16 KSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPdrdgelvpadrrqLQRIRT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:COG4598 96 RLGMVFQSFNLWSHMTVLENVIEAPvHVLGRPKAEAIERAEALLAKVGL-ADKRDAYPAHLSGGQQQRAAIARALAMEPE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 155 VLLMDEPFGALDPvtrgALQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFV 231
Cdd:COG4598 175 VMLFDEPTSALDP----ELVGEVLKVMRDLaeeGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNPKSERL 250
|
...
gi 581977852 232 QAF 234
Cdd:COG4598 251 RQF 253
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
2-228 |
4.54e-52 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 171.71 E-value: 4.54e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGV-----IRFAGEEIRS--LPVLELR 74
Cdd:TIGR00972 2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRMNDLVPGVriegkVLFDGQDIYDkkIDVVELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 RRMGYAIQSIGLFPHwTVAQNIATVPQLQKW-SRSRIDDRTEELM--ALLGLDVNLR-HRYPHQLSGGQQQRVGVARALA 150
Cdd:TIGR00972 82 RRVGMVFQKPNPFPM-SIYDNIAYGPRLHGIkDKKELDEIVEESLkkAALWDEVKDRlHDSALGLSGGQQQRLCIARALA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 151 ADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAN 228
Cdd:TIGR00972 161 VEPEVLLLDEPTSALDPIATGKIEELIQELKKKY--TIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKE 236
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-227 |
8.93e-52 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 170.65 E-value: 8.93e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRslpvlELRRRMGYA 80
Cdd:COG1121 6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPR-----RARRRIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGL---FPhwtvaqniATV---------PQLQKWSRSRIDDRT--EELMALLGLDvNLRHRYPHQLSGGQQQRVGVA 146
Cdd:COG1121 81 PQRAEVdwdFP--------ITVrdvvlmgryGRRGLFRRPSRADREavDEALERVGLE-DLADRPIGELSGGQQQRVLLA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 147 RALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGeVVQQGTPLEMLTAP 226
Cdd:COG1121 152 RALAQDPDLLLLDEPFAGVDAATEEALYELLRELRR-EGKTILVVTHDLGAVREYFDRVLLLNRG-LVAHGPPEEVLTPE 229
|
.
gi 581977852 227 A 227
Cdd:COG1121 230 N 230
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
2-218 |
9.12e-52 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 170.58 E-value: 9.12e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEE------IRSLPVLELRR 75
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQfdfsqkPSEKAIRLLRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:COG4161 83 KVGMVFQQYNLWPHLTVMENLIEAPcKVLGLSKEQAREKAMKLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 155 VLLMDEPFGALDPvtrgALQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGT 218
Cdd:COG4161 162 VLLFDEPTAALDP----EITAQVVEIIRELsqtGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD 224
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
2-213 |
1.04e-51 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 169.23 E-value: 1.04e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAI 81
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQVAYVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHwTVAQNIATVPQLQKwsRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:COG4619 81 QEPALWGG-TVRDNLPFPFQLRE--RKFDRERALELLERLGLPPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:COG4619 158 TSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-217 |
1.40e-51 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 168.00 E-value: 1.40e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 3 EFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYaiq 82
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAY--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 siglfphwtvaqniatVPQlqkwsrsriddrteeLMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPF 162
Cdd:cd03214 78 ----------------VPQ---------------ALELLGLA-HLADRPFNELSGGERQRVLLARALAQEPPILLLDEPT 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 163 GALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03214 126 SHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-227 |
1.74e-51 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 169.54 E-value: 1.74e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYA 80
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLgIGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQK----------WSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALA 150
Cdd:cd03219 81 FQIPRLFPELTVLENVMVAAQARTgsglllararREEREARERAEELLERVGLA-DLADRPAGELSYGQQRRLEIARALA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 151 ADPQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:cd03219 160 TDPKLLLLDEPAAGLNPEETEELAELIRELRE-RGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPR 235
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-236 |
1.26e-49 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 165.60 E-value: 1.26e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGV-----IRFAGEEI--RSLPVLELR 74
Cdd:COG1117 12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGArvegeILLDGEDIydPDVDVVELR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 RRMGYAIQSIGLFPHwTVAQNIATVPQLQKW-SRSRIDDRTEElmAL--LGL--DVNLR-HRYPHQLSGGQQQRVGVARA 148
Cdd:COG1117 92 RRVGMVFQKPNPFPK-SIYDNVAYGLRLHGIkSKSELDEIVEE--SLrkAALwdEVKDRlKKSALGLSGGQQQRLCIARA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALqqEMTrIHRLLGR-TIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:COG1117 169 LAVEPEVLLMDEPTSALDPISTAKI--EEL-ILELKKDyTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTNPK 245
|
250
....*....|...
gi 581977852 228 N----DFVQAFFG 236
Cdd:COG1117 246 DkrteDYITGRFG 258
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-221 |
2.16e-49 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 164.39 E-value: 2.16e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQK-AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSL---PVLELRRR 76
Cdd:TIGR02315 1 MLEVENLSKVYPNGKqALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLrgkKLRKLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNI-----ATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRY---PHQLSGGQQQRVGVARA 148
Cdd:TIGR02315 81 IGMIFQHYNLIERLTVLENVlhgrlGYKPTWRSLLGRFSEEDKERALSALER-VGLADKAyqrADQLSGGQQQRVAIARA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLE 221
Cdd:TIGR02315 160 LAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSE 232
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-227 |
6.68e-49 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 165.61 E-value: 6.68e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF----GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVE---HDSGVIRFAGEEIRSLPVLEL 73
Cdd:COG0444 1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAIQSIglF--------PHWTVAQNIATVPQL-QKWSRSRIDDRTEELMALLGLDVNLRH--RYPHQLSGGQQQR 142
Cdd:COG0444 81 RKIRGREIQMI--FqdpmtslnPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLPDPERRldRYPHELSGGMRQR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 143 VGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:COG0444 159 VMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEEL 238
|
....*
gi 581977852 223 LTAPA 227
Cdd:COG0444 239 FENPR 243
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-237 |
6.87e-49 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 163.00 E-value: 6.87e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAvnDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYA 80
Cdd:COG3840 1 MLRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAE--RPVSML 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIA---------TVPQlqkwsRSRIddrtEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAA 151
Cdd:COG3840 77 FQENNLFPHLTVAQNIGlglrpglklTAEQ-----RAQV----EQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVR 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 152 DPQVLLMDEPFGALDPvtrgALQQEM----TRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:COG3840 147 KRPILLLDEPFSALDP----ALRQEMldlvDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEP 222
|
250
....*....|
gi 581977852 228 NDFVQAFFGR 237
Cdd:COG3840 223 PPALAAYLGI 232
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-226 |
1.18e-47 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 160.25 E-value: 1.18e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMgyA 80
Cdd:COG4604 1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRL--A 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 I--QSI--------------GLFPHwtvaqniatvpqlqkwSRSRI--DDRT--EELMALLGLDvNLRHRYPHQLSGGQQ 140
Cdd:COG4604 79 IlrQENhinsrltvrelvafGRFPY----------------SKGRLtaEDREiiDEAIAYLDLE-DLADRYLDELSGGQR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 141 QRVGVARALAADPQVLLMDEPFGALDPvtRGALQQeMTRIHRL---LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:COG4604 142 QRAFIAMVLAQDTDYVLLDEPLNNLDM--KHSVQM-MKLLRRLadeLGKTVVIVLHDINFASCYADHIVAMKDGRVVAQG 218
|
....*....
gi 581977852 218 TPLEMLTAP 226
Cdd:COG4604 219 TPEEIITPE 227
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-221 |
1.44e-47 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 160.67 E-value: 1.44e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlP--VLELRRRM 77
Cdd:TIGR04520 1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLD-EenLWEIRKKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQS-----IGLfphwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAAD 152
Cdd:TIGR04520 80 GMVFQNpdnqfVGA----TVEDDVAFGLENLGVPREEMRKRVDEALKLVGME-DFRDREPHLLSGGQKQRVAIAGVLAMR 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALrLAEHLVLMDGGEVVQQGTPLE 221
Cdd:TIGR04520 155 PDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAEGTPRE 222
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-215 |
1.84e-47 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 159.87 E-value: 1.84e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeirsLPVLELRRRMGYA 80
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDG-----KPVEGPGAERGVV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:PRK11248 76 FQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLE-GAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLM--DGGEVVQ 215
Cdd:PRK11248 155 PFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLspGPGRVVE 211
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-282 |
4.14e-47 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 160.27 E-value: 4.14e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlpvlELRRRMGYA 80
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDP----EDRRRIGYL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGL----DVNLRhryphQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG4152 77 PEERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLgdraNKKVE-----ELSKGNQQKVQLIAALLHDPELL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRiHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMltapandfvqaffg 236
Cdd:COG4152 152 ILDEPFSGLDPVNVELLKDVIRE-LAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI-------------- 216
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 237 RSELGVRLLSLRSVGDY--------VRRHEQVGGDA---LAEEMTLRDALSVFVARG 282
Cdd:COG4152 217 RRQFGRNTLRLEADGDAgwlralpgVTVVEEDGDGAelkLEDGADAQELLRALLARG 273
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-221 |
4.66e-47 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 157.67 E-value: 4.66e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG--AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGY 79
Cdd:cd03263 1 LQIRNLTKTYKkgTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRK-AARQSLGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:cd03263 80 CPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGL-TDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 160 EPFGALDPVTRgalqqemTRIHRLL-----GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLE 221
Cdd:cd03263 159 EPTSGLDPASR-------RAIWDLIlevrkGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
2-227 |
4.71e-47 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 159.80 E-value: 4.71e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVS-----KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI----RSLPVLE 72
Cdd:PRK13634 3 ITFQKVEhryqyKTPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVItagkKNKKLKP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVAR 147
Cdd:PRK13634 83 LRKKVGIVFQ----FPEHqlfeeTVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:PRK13634 159 VLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
1-212 |
5.73e-47 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 157.41 E-value: 5.73e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRR 76
Cdd:TIGR02673 1 MIEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRgrqLPLLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHrYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:TIGR02673 81 IGVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADA-FPEQLSGGEQQRVAIARAIVNSPPLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGE 212
Cdd:TIGR02673 160 LADEPTGNLDPDLSERILDLLKRLNK-RGTTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
17-222 |
5.94e-47 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 158.01 E-value: 5.94e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlPVLElrrRMgYAIQSIGLFPHWTVAQNI 96
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITE-PGPD---RM-VVFQNYSLLPWLTVRENI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 97 A-----TVPQLQKWSRSRIddrTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRG 171
Cdd:TIGR01184 76 AlavdrVLPDLSKSERRAI---VEEHIALVGLT-EAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 172 ALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:TIGR01184 152 NLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEV 202
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-237 |
6.03e-47 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 158.37 E-value: 6.03e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI---RSLP-----VLE 72
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIdtaRSLSqqkglIRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAA 151
Cdd:PRK11264 83 LRQHVGFVFQNFNLFPHRTVLENIIEGPvIVKGEPKEEATARARELLAKVGLA-GKETSYPRRLSGGQQQRVAIARALAM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALqqeMTRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAND 229
Cdd:PRK11264 162 RPEVILFDEPTSALDPELVGEV---LNTIRQLAqeKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQP 238
|
....*...
gi 581977852 230 FVQAFFGR 237
Cdd:PRK11264 239 RTRQFLEK 246
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-218 |
1.05e-46 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 157.48 E-value: 1.05e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAG------EEIRSLPVLELRR 75
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhfdfsKTPSDKAIRELRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:PRK11124 83 NVGMVFQQYNLWPHLTVQQNLIEAPcRVLGLSKDQALARAEKLLERLRLK-PYADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 155 VLLMDEPFGALDP-VTrgalQQEMTRIHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGT 218
Cdd:PRK11124 162 VLLFDEPTAALDPeIT----AQIVSIIRELaeTGITQVIVTHEVEVARKTASRVVYMENGHIVEQGD 224
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-212 |
2.76e-46 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 154.08 E-value: 2.76e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG--AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:cd03228 1 IEFKNVSFSYPgrPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFpHWTVAQNIatvpqlqkwsrsriddrteelmallgldvnlrhryphqLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:cd03228 81 VPQDPFLF-SGTIRENI--------------------------------------LSGGQRQRIAIARALLRDPPILILD 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 581977852 160 EPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGE 212
Cdd:cd03228 122 EATSALDPETEALILEALRALAK--GKTVIVIAHRL-STIRDADRIIVLDDGR 171
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
2-240 |
6.79e-46 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 158.73 E-value: 6.79e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLPvlelRRRMGY 79
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVthRSIQ----QRDICM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:PRK11432 83 VFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLA-GFEDRYVDQISGGQQQRVALARALILKPKVLLFD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 160 EPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGRSE 239
Cdd:PRK11432 162 EPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDAN 241
|
.
gi 581977852 240 L 240
Cdd:PRK11432 242 I 242
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-223 |
1.76e-45 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 163.85 E-value: 1.76e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG--AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:COG2274 474 IELENVSFRYPgdSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGV 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFpHWTVAQNIAtvpqlqkWSRSRIDDR-----------TEELMAL-LGLDVNLRHRYpHQLSGGQQQRVGVAR 147
Cdd:COG2274 554 VLQDVFLF-SGTIRENIT-------LGDPDATDEeiieaarlaglHDFIEALpMGYDTVVGEGG-SNLSGGQRQRLAIAR 624
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDiDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:COG2274 625 ALLRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHR-LSTIRLADRIIVLDKGRIVEDGTHEELL 697
|
|
| ABC_ATP_SaoA |
NF040729 |
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ... |
2-215 |
2.23e-45 |
|
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC transporter in which both the permease subunit SaoP, and the substrate-binding protein SaoB, are nearly always selenoproteins that were unrecognized as such until recently (2022). The SAO system is found in Clostridium difficile and various other anaerobic heterotrophs.
Pssm-ID: 468693 [Multi-domain] Cd Length: 248 Bit Score: 154.51 E-value: 2.23e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVN----DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIrSLPVLElrrrM 77
Cdd:NF040729 2 LKIQNISKTFINNKKENevlkDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNATSGEILVNGNEV-TKPGPD----R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNlRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:NF040729 77 GFVFQNYALFPWMTVKENIEYPMKQQKMPKQEREKRLNELLEMAQLTGK-ENLYPHQISGGMKQRTAVIRALACKPEVLL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLM--DGGEVVQ 215
Cdd:NF040729 156 MDEPLGAVDFQMRQILQEELESIWLKDKTTVLMVTHDVDEAVYLSDRVIVMsrDKGKILE 215
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-223 |
5.32e-45 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 152.88 E-value: 5.32e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElRRRMG-- 78
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHK-RARLGig 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQ--SIglFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG1137 82 YLPQeaSI--FRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGIT-HLRKSKAYSLSGGERRRVEIARALATNPKFI 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 157 LMDEPFGALDPVTRGALQQEmtrIHRLLGRTI-VLVT-HDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:COG1137 159 LLDEPFAGVDPIAVADIQKI---IRHLKERGIgVLITdHNVRETLGICDRAYIISEGKVLAEGTPEEIL 224
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-212 |
5.45e-45 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 150.47 E-value: 5.45e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 3 EFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAiq 82
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYV-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 siglfphwtvaqniatvpqlqkwsrsriddrteelmallgldvnlrhrypHQLSGGQQQRVGVARALAADPQVLLMDEPF 162
Cdd:cd00267 79 --------------------------------------------------PQLSGGQRQRVALARALLLNPDLLLLDEPT 108
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 581977852 163 GALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGE 212
Cdd:cd00267 109 SGLDPASRERLLELLRELAE-EGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-217 |
9.70e-45 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 151.58 E-value: 9.70e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGsFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAI 81
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQ-KLRRRIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGL-DVnlRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:cd03264 79 QEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLgDR--AKKKIGSLSGGMRRRVGIAQALVGDPSILIVDE 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 161 PFGALDPVTRgalqqemTRIHRLLG-----RTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03264 157 PTAGLDPEER-------IRFRNLLSelgedRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-227 |
1.61e-44 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 151.54 E-value: 1.61e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYA 80
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLgIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:cd03218 81 PQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHIT-HLRKSKASSLSGGERRRVEIARALATNPKFLLLDE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 161 PFGALDPVTRGALQQemtRIHRLLGRTI-VLVT-HDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:cd03218 160 PFAGVDPIAVQDIQK---IIKILKDRGIgVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-236 |
1.62e-44 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 155.00 E-value: 1.62e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLpvlELRRRmGY 79
Cdd:PRK11650 3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNEL---EPADR-DI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AI--QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK11650 79 AMvfQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELE-PLLDRKPRELSGGQRQRVAMGRAIVREPAVFL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:PRK11650 158 FDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFIG 236
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
6-194 |
7.51e-43 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 146.61 E-value: 7.51e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 6 HVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEE---IRSLPVLELRR-RMGYAI 81
Cdd:TIGR03608 3 NISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQEtppLNSKKASKFRReKLGYLF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLrHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:TIGR03608 83 QNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKL-KQKIYELSGGEQQRVALARAILKPPPLILADEP 161
|
170 180 190
....*....|....*....|....*....|....*.
gi 581977852 162 FGALDPVTRgalqQEMTRIHRLL---GRTIVLVTHD 194
Cdd:TIGR03608 162 TGSLDPKNR----DEVLDLLLELndeGKTIIIVTHD 193
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-222 |
9.33e-43 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 146.75 E-value: 9.33e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAI 81
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPR-EVRRRIGIVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03265 80 QDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGL-LEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:cd03265 159 TIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-236 |
1.04e-42 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 147.54 E-value: 1.04e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRlvEH---DSGVIRFAGEEIRSLPVLELRRRM 77
Cdd:COG1119 3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITG--DLpptYGNDVRLFGERRGGEDVWELRKRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GY---AIQ-------------------SIGLFPHWTVAQniatvpqlqkwsrsriDDRTEELMALLGLDvNLRHRYPHQL 135
Cdd:COG1119 81 GLvspALQlrfprdetvldvvlsgffdSIGLYREPTDEQ----------------RERARELLELLGLA-HLADRPFGTL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 136 SGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQ 215
Cdd:COG1119 144 SQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVA 223
|
250 260
....*....|....*....|.
gi 581977852 216 QGTPLEMLTApanDFVQAFFG 236
Cdd:COG1119 224 AGPKEEVLTS---ENLSEAFG 241
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-223 |
1.27e-42 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 154.15 E-value: 1.27e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:COG4988 337 IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQIAWV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFpHWTVAQNI------ATVPQLQKWSR-SRIDDRTEELMAllGLDVNL--RHRyphQLSGGQQQRVGVARALAA 151
Cdd:COG4988 417 PQNPYLF-AGTIRENLrlgrpdASDEELEAALEaAGLDEFVAALPD--GLDTPLgeGGR---GLSGGQAQRLALARALLR 490
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:COG4988 491 DAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRL-ALLAQADRILVLDDGRIVEQGTHEELL 559
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
13-221 |
3.66e-42 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 147.12 E-value: 3.66e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 13 AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLPVLELRRRMGYAIQsiglFPHW 90
Cdd:PRK13637 19 EKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItdKKVKLSDIRKKVGLVFQ----YPEY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 -----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVN-LRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGA 164
Cdd:PRK13637 95 qlfeeTIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDYEdYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAG 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 165 LDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLE 221
Cdd:PRK13637 175 LDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPRE 231
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
2-223 |
8.61e-42 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 152.24 E-value: 8.61e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSktF---GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:COG1132 340 IEFENVS--FsypGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIG 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFpHWTVAQNIAtvpqlqkWSRSRIDDrtEELMALL--------------GLDVNLRHRyPHQLSGGQQQRVG 144
Cdd:COG1132 418 VVPQDTFLF-SGTIRENIR-------YGRPDATD--EEVEEAAkaaqahefiealpdGYDTVVGER-GVNLSGGQRQRIA 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 145 VARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:COG1132 487 IARALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRL-STIRNADRILVLDDGRIVEQGTHEELL 562
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-209 |
2.04e-41 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 142.62 E-value: 2.04e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYA 80
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARE-DYRRRLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRidDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:COG4133 81 GHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLA-GLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDE 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 581977852 161 PFGALDPVTRGALQQEMTRiHRLLGRTIVLVTHDiDEALRLAEHLVLMD 209
Cdd:COG4133 158 PFTALDAAGVALLAELIAA-HLARGGAVLLTTHQ-PLELAAARVLDLGD 204
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-217 |
2.29e-41 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 142.80 E-value: 2.29e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlelRRRMGYAI 81
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA----RNRIGYLP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03269 77 EERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELS-EYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 162 FGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03269 156 FSGLDPVNVELLKDVIRELAR-AGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-194 |
2.72e-41 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 142.55 E-value: 2.72e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQ-KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRRM 77
Cdd:cd03292 1 IEFINVTKTYPNGtAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRgraIPYLRRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLS-HKHRALPAELSGGEQQRVAIARAIVNSPTILI 159
|
170 180 190
....*....|....*....|....*....|....*..
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHrLLGRTIVLVTHD 194
Cdd:cd03292 160 ADEPTGNLDPDTTWEIMNLLKKIN-KAGTTVVVATHA 195
|
|
| ABC_ATP_DarD |
NF038007 |
darobactin export ABC transporter ATP-binding protein; |
1-211 |
2.76e-41 |
|
darobactin export ABC transporter ATP-binding protein;
Pssm-ID: 411600 [Multi-domain] Cd Length: 218 Bit Score: 142.94 E-value: 2.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQ----KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLE---L 73
Cdd:NF038007 1 MLNMQNAEKCYITKtiktKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQkiiL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRM-GYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAAD 152
Cdd:NF038007 81 RRELiGYIFQSFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGID-NRRNHKPMQLSGGQQQRVAIARAMVSN 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDiDEALRLAEHLVLMDGG 211
Cdd:NF038007 160 PALLLADEPTGNLDSKNARAVLQQLKYINQ-KGTTIIMVTHS-DEASTYGNRIINMKDG 216
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-224 |
4.50e-41 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 143.98 E-value: 4.50e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQK--AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:PRK13632 7 MIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKKIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQS-----IGLfphwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADP 153
Cdd:PRK13632 87 IIFQNpdnqfIGA----TVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGME-DYLDKEPQNLSGGQKQRVAIASVLALNP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 154 QVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALrLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:PRK13632 162 EIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEILN 231
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
17-162 |
4.70e-41 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 140.09 E-value: 4.70e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWTVAQNI 96
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 97 ATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHR----YPHQLSGGQQQRVGVARALAADPQVLLMDEPF 162
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGL-GDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
3-217 |
5.07e-41 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 141.90 E-value: 5.07e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 3 EFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEeirslPVLELRRRMGYAIQ 82
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK-----PLEKERKRIGYVPQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 SIGL---FPhWTVAQNIATVPQLQKWSRSRID----DRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:cd03235 76 RRSIdrdFP-ISVRDVVLMGLYGHKGLFRRLSkadkAKVDEALERVGL-SELADRQIGELSGGQQQRVLLARALVQDPDL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDgGEVVQQG 217
Cdd:cd03235 154 LLLDEPFAGVDPKTQEDIYELLRELRR-EGMTILVVTHDLGLVLEYFDRVLLLN-RTVVASG 213
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
32-227 |
7.81e-41 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 145.64 E-value: 7.81e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 32 LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRS------LPVLelRRRMGYAIQSIGLFPHWTVAQNIatvpqLQKW 105
Cdd:TIGR02142 28 IFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrkgifLPPE--KRRIGYVFQEARLFPHLSVRGNL-----RYGM 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 106 SRSRIDDRT---EELMALLGLDVNLRhRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHR 182
Cdd:TIGR02142 101 KRARPSERRisfERVIELLGIGHLLG-RLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYLERLHA 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 581977852 183 LLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:TIGR02142 180 EFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPD 224
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-223 |
8.83e-41 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 141.42 E-value: 8.83e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYA 80
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKwsRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:cd03224 81 PEGRRIFPELTVEENLLLGAYARR--RAKRKARLERVYELFPRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:cd03224 159 PSEGLAPKIVEEIFEAIRELRD-EGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELL 220
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
9-235 |
9.09e-41 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 142.80 E-value: 9.09e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 9 KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR-------SLPVLE------LRR 75
Cdd:PRK10619 13 KRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgQLKVADknqlrlLRT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQSIGLFPHWTVAQNIATVP-QLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:PRK10619 93 RLTMVFQHFNLWSHMTVLENVMEAPiQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALAMEPE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 155 VLLMDEPFGALDPVTRGalqqEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFV 231
Cdd:PRK10619 173 VLLFDEPTSALDPELVG----EVLRIMQQLaeeGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRL 248
|
....
gi 581977852 232 QAFF 235
Cdd:PRK10619 249 QQFL 252
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-234 |
9.72e-41 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 142.36 E-value: 9.72e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVE-----HDSGVIRFAGEEIRSLPVLELRRR 76
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElypeaRVSGEVYLDGQDIFKMDVIELRRR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSR--IDDRTEELM--ALLGLDVNLRHRYPH-QLSGGQQQRVGVARALAA 151
Cdd:PRK14247 84 VQMVFQIPNPIPNLSIFENVALGLKLNRLVKSKkeLQERVRWALekAQLWDEVKDRLDAPAgKLSGGQQQRLCIARALAF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFV 231
Cdd:PRK14247 164 QPEVLLADEPTANLDPENTAKIESLFLELKKDM--TIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELT 241
|
...
gi 581977852 232 QAF 234
Cdd:PRK14247 242 EKY 244
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
9-222 |
1.33e-40 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 143.68 E-value: 1.33e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 9 KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAIQSIGLFP 88
Cdd:TIGR01188 1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPR-KVRRSIGIVPQYASVDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 89 HWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPV 168
Cdd:TIGR01188 80 DLTGRENLEMMGRLYGLPKDEAEERAEELLELFEL-GEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPR 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 581977852 169 TRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:TIGR01188 159 TRRAIWDYIRALKE-EGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEEL 211
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-236 |
2.39e-40 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 140.89 E-value: 2.39e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGY 79
Cdd:COG0410 3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLgIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQKwSRSRIDDRTEELMAL---LGldvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG0410 83 VPEGRRIFPSLTVEENLLLGAYARR-DRAEVRADLERVYELfprLK---ERRRQRAGTLSGGEQQMLAIGRALMSRPKLL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 157 LMDEPFGALDPVtrgaLQQEMTR-IHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPanDFVQA 233
Cdd:COG0410 159 LLDEPSLGLAPL----IVEEIFEiIRRLnrEGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADP--EVREA 232
|
...
gi 581977852 234 FFG 236
Cdd:COG0410 233 YLG 235
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-227 |
1.62e-39 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 145.68 E-value: 1.62e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:COG4987 334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRIAV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFpHWTVAQNIATVpqlqkwsRSRIDDrtEELMALL---GLDvNLRHRYPH-----------QLSGGQQQRVGV 145
Cdd:COG4987 414 VPQRPHLF-DTTLRENLRLA-------RPDATD--EELWAALervGLG-DWLAALPDgldtwlgeggrRLSGGERRRLAL 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 146 ARALAADPQVLLMDEPFGALDPVTRGALqqeMTRIHRLL-GRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:COG4987 483 ARALLRDAPILLLDEPTEGLDAATEQAL---LADLLEALaGRTVLLITHRL-AGLERMDRILVLEDGRIVEQGTHEELLA 558
|
...
gi 581977852 225 APA 227
Cdd:COG4987 559 QNG 561
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-226 |
2.61e-39 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 138.71 E-value: 2.61e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:COG4559 1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGL-FPhWTVAQNIA--TVPQLQkwSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALA------- 150
Cdd:COG4559 81 PQHSSLaFP-FTVEEVVAlgRAPHGS--SAAQDRQIVREALALVGLA-HLAGRSYQTLSGGEQQRVQLARVLAqlwepvd 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 151 ADPQVLLMDEPFGALDPvtrgALQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:COG4559 157 GGPRWLFLDEPTSALDL----AHQHAVLRLARQLarrGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDE 231
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
8-194 |
4.52e-39 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 140.25 E-value: 4.52e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 8 SKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRRMGYAIQ-- 82
Cdd:COG4608 25 GRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSgreLRPLRRRMQMVFQdp 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 --SigLFPHWTVAQNIATVPQLQK-WSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:COG4608 105 yaS--LNPRMTVGDIIAEPLRIHGlASKAERRERVAELLELVGLRPEHADRYPHEFSGGQRQRIGIARALALNPKLIVCD 182
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 581977852 160 EPFGALDpVTRGA--------LQQEmtrihrlLGRTIVLVTHD 194
Cdd:COG4608 183 EPVSALD-VSIQAqvlnlledLQDE-------LGLTYLFISHD 217
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
9-233 |
1.45e-37 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 139.82 E-value: 1.45e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 9 KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHdSGVIRFAGEEIRSLP---VLELRRRMGYAIQ--- 82
Cdd:COG4172 294 RTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPS-EGEIRFDGQDLDGLSrraLRPLRRRMQVVFQdpf 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 -SigLFPHWTVAQNIA---TVPQLQkWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:COG4172 373 gS--LSPRMTVGQIIAeglRVHGPG-LSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVL 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 159 DEPFGALDpVTRGA--------LQQEmtriHRLlgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDF 230
Cdd:COG4172 450 DEPTSALD-VSVQAqildllrdLQRE----HGL---AYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPY 521
|
...
gi 581977852 231 VQA 233
Cdd:COG4172 522 TRA 524
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-223 |
2.23e-37 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 133.12 E-value: 2.23e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK-AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:cd03254 3 IEFENVNFSYDEKKpVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHwTVAQNIatvpqlqKWSRSRIDDRTEELMALL------------GLDVNLRHRyPHQLSGGQQQRVGVARA 148
Cdd:cd03254 83 LQDTFLFSG-TIMENI-------RLGRPNATDEEVIEAAKEagahdfimklpnGYDTVLGEN-GGNLSQGERQLLAIARA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIhrLLGRTIVLVTHdidealRL-----AEHLVLMDGGEVVQQGTPLEML 223
Cdd:cd03254 154 MLRDPKILILDEATSNIDTETEKLIQEALEKL--MKGRTSIIIAH------RLstiknADKILVLDDGKIIEEGTHDELL 225
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
19-217 |
2.56e-37 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 132.23 E-value: 2.56e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrRRMGYAIQSIGLFPHWTVAQNI-- 96
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPAD--RPVSMLFQENNLFAHLTVEQNVgl 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 97 ATVPQLQKWSRSRidDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQE 176
Cdd:cd03298 94 GLSPGLKLTAEDR--QAIEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDL 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 581977852 177 MTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03298 171 VLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-267 |
4.25e-37 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 138.23 E-value: 4.25e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElRRRMGYA 80
Cdd:COG1129 4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRD-AQAAGIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 I--QSIGLFPHWTVAQNIAtvpqLQKWSRSR--IDDR-----TEELMALLGLDVNLRHRYpHQLSGGQQQRVGVARALAA 151
Cdd:COG1129 83 IihQELNLVPNLSVAENIF----LGREPRRGglIDWRamrrrARELLARLGLDIDPDTPV-GDLSVAQQQLVEIARALSR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALqqeMTRIHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVqqgtplemLTAPAND 229
Cdd:COG1129 158 DARVLILDEPTASLTEREVERL---FRIIRRLkaQGVAIIYISHRLDEVFEIADRVTVLRDGRLV--------GTGPVAE 226
|
250 260 270
....*....|....*....|....*....|....*...
gi 581977852 230 fvqafFGRSELgVRLLSLRSVGDYVRRHEQVGGDALAE 267
Cdd:COG1129 227 -----LTEDEL-VRLMVGRELEDLFPKRAAAPGEVVLE 258
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
17-234 |
4.47e-37 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 133.25 E-value: 4.47e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVE-HDS-----GVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHW 90
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiYDSkikvdGKVLYFGKDIFQIDAIKLRKEVGMVFQQPNPFPHL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIATVPQLQKWSRSR-IDDRTEELMALLGL--DVNLRHRYP-HQLSGGQQQRVGVARALAADPQVLLMDEPFGALD 166
Cdd:PRK14246 106 SIYDNIAYPLKSHGIKEKReIKKIVEECLRKVGLwkEVYDRLNSPaSQLSGGQQQRLTIARALALKPKVLLMDEPTSMID 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 167 PVTRGALQQEMTRIHRLLgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAF 234
Cdd:PRK14246 186 IVNSQAIEKLITELKNEI--AIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKY 251
|
|
| heterocyst_DevA |
TIGR02982 |
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ... |
2-214 |
6.78e-37 |
|
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.
Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 131.29 E-value: 6.78e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG---AQKAV-NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELR 74
Cdd:TIGR02982 2 ISIRNLNHYYGhgsLRKQVlFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGASkkqLVQLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 RRMGYAIQSIGLFPHWTVAQNIATVPQLQ-KWSRSRIDDRTEELMALLGLDVNLrHRYPHQLSGGQQQRVGVARALAADP 153
Cdd:TIGR02982 82 RRIGYIFQAHNLLGFLTARQNVQMALELQpNLSYQEARERARAMLEAVGLGDHL-NYYPHNLSGGQKQRVAIARALVHHP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 154 QVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDiDEALRLAEHLVLMDGGEVV 214
Cdd:TIGR02982 161 KLVLADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHD-NRILDVADRILQMEDGKLL 220
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-217 |
8.43e-37 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 130.80 E-value: 8.43e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlELRRRMGYAI 81
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNI--EALRRIGALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDdrteELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03268 79 EAPGFYPNLTARENLRLLARLLGIRKKRID----EVLDVVGLK-DSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEP 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 162 FGALDPVtrGALQ-QEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03268 154 TNGLDPD--GIKElRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
1-207 |
1.22e-36 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 130.29 E-value: 1.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD---SGVIRFAGEEIRSLPVLelRRRM 77
Cdd:COG4136 1 MLSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTALPAE--QRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNIA-TVPQlqKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG4136 79 GILFQDDLLFPHLSVGENLAfALPP--TIGRAQRRARVEQALEEAGLA-GFADRDPATLSGGQRARVALLRALLAEPRAL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 157 LMDEPFGALDPVTRGA-LQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVL 207
Cdd:COG4136 156 LLDEPFSKLDAALRAQfREFVFEQIRQ-RGIPALLVTHDEEDAPAAGRVLDL 206
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-225 |
1.60e-36 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 131.43 E-value: 1.60e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGL-FPhWTVAQNIA--TVPqlqkWSRSRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALA----- 150
Cdd:PRK13548 82 PQHSSLsFP-FTVEEVVAmgRAP----HGLSRAEDDalVAAALAQVDLA-HLAGRDYPQLSGGEQQRVQLARVLAqlwep 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 151 -ADPQVLLMDEPFGALDPvtrgALQQEMTRIHRLL----GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:PRK13548 156 dGPPRWLLLDEPTSALDL----AHQHHVLRLARQLaherGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLTP 231
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
2-219 |
1.80e-36 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 132.18 E-value: 1.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGA-----QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP----VLE 72
Cdd:PRK13649 3 INLQNVSYTYQAgtpfeGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSknkdIKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVAR 147
Cdd:PRK13649 83 IRKKVGLVFQ----FPESqlfeeTVLKDVAFGPQNFGVSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTP 219
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQ-SGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKP 229
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
2-217 |
1.84e-36 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 130.40 E-value: 1.84e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK--AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:cd03245 3 IEFRNVSFSYPNQEipALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFpHWTVAQNIATvpqlqkwSRSRIDDrtEELMA---LLGLDVNLRhRYPH-----------QLSGGQQQRVGV 145
Cdd:cd03245 83 VPQDVTLF-YGTLRDNITL-------GAPLADD--ERILRaaeLAGVTDFVN-KHPNgldlqigergrGLSGGQRQAVAL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 146 ARALAADPQVLLMDEPFGALDpvtrgaLQQEMTRIHRL----LGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03245 152 ARALLNDPPILLLDEPTSAMD------MNSEERLKERLrqllGDKTLIIITHRP-SLLDLVDRIIVMDSGRIVADG 220
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1-242 |
2.16e-36 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 132.16 E-value: 2.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFG-----AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP----VL 71
Cdd:PRK13643 1 MIKFEKVNYTYQpnspfASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSkqkeIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 72 ELRRRMGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVA 146
Cdd:PRK13643 81 PVRKKVGVVFQ----FPESqlfeeTVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 147 RALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK13643 157 GILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQ-SGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEV 235
|
250
....*....|....*.
gi 581977852 227 anDFVQAffgrSELGV 242
Cdd:PRK13643 236 --DFLKA----HELGV 245
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-225 |
5.45e-36 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 130.13 E-value: 5.45e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQsIGLFPHW-TVAQNIA--TVPQLQKWSRSRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:PRK11231 82 PQ-HHLTPEGiTVRELVAygRSPWLSLWGRLSAEDNarVNQAMEQTRIN-HLADRRLTDLSGGQRQRAFLAMVLAQDTPV 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 156 LLMDEPFGALDpVTRgalQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:PRK11231 160 VLLDEPTTYLD-INH---QVELMRLMRELntqGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTP 228
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
2-225 |
6.70e-36 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 136.92 E-value: 6.70e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQ-KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:TIGR03375 464 IEFRNVSFAYpGQEtPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRRNIGY 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFpHWTVAQNIATvpqlqkwSRSRIDDrtEELMALL---GLDvNLRHRYPH-----------QLSGGQQQRVGV 145
Cdd:TIGR03375 544 VPQDPRLF-YGTLRDNIAL-------GAPYADD--EEILRAAelaGVT-EFVRRHPDgldmqigergrSLSGGQRQAVAL 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 146 ARALAADPQVLLMDEPFGALDpvtrgaLQQEMTRIHRL----LGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLE 221
Cdd:TIGR03375 613 ARALLRDPPILLLDEPTSAMD------NRSEERFKDRLkrwlAGKTLVLVTHRT-SLLDLVDRIIVMDNGRIVADGPKDQ 685
|
....
gi 581977852 222 MLTA 225
Cdd:TIGR03375 686 VLEA 689
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
2-223 |
7.75e-36 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 129.20 E-value: 7.75e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGA---QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:cd03249 1 IEFKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHwTVAQNI------ATVPQLQKWSR-SRIDDRTEELMAllGLDVNLRHRYPhQLSGGQQQRVGVARALAA 151
Cdd:cd03249 81 LVSQEPVLFDG-TIAENIrygkpdATDEEVEEAAKkANIHDFIMSLPD--GYDTLVGERGS-QLSGGQKQRIAIARALLR 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:cd03249 157 NPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRL-STIRNADLIAVLQNGQVVEQGTHDELM 225
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-234 |
1.13e-35 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 129.19 E-value: 1.13e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD-----SGVIRFAGEEIRSLPV--LELR 74
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIYSPDVdpIEVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 RRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSR--IDDRTEELMALLGLDVNLRHR---YPHQLSGGQQQRVGVARAL 149
Cdd:PRK14267 85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKSKkeLDERVEWALKKAALWDEVKDRlndYPSNLSGGQRQRLVIARAL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 150 AADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAND 229
Cdd:PRK14267 165 AMKPKILLMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHE 242
|
....*
gi 581977852 230 FVQAF 234
Cdd:PRK14267 243 LTEKY 247
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
2-221 |
1.39e-35 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 129.75 E-value: 1.39e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:PRK13635 6 IRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQVGM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSI-GLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLrHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:PRK13635 86 VFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFL-NREPHRLSGGQKQRVAIAGVLALQPDIIIL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 159 DEPFGALDPVTRgalQQEMTRIHRL---LGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTPLE 221
Cdd:PRK13635 165 DEATSMLDPRGR---REVLETVRQLkeqKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEE 226
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-215 |
3.86e-35 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 127.16 E-value: 3.86e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFG-AQKAVN---DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSL---PVLEL 73
Cdd:COG4181 8 IIELRGLTKTVGtGAGELTilkGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALdedARARL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRR-MGYAIQSIGLFPHWTVAQNIATVPQLQkwSRSRIDDRTEELMALLGLDVNLRHrYPHQLSGGQQQRVGVARALAAD 152
Cdd:COG4181 88 RARhVGFVFQSFQLLPTLTALENVMLPLELA--GRRDARARARALLERVGLGHRLDH-YPAQLSGGEQQRVALARAFATE 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQ 215
Cdd:COG4181 165 PAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLVE 226
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
2-222 |
6.63e-35 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 127.97 E-value: 6.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFgaQK-------AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP----V 70
Cdd:PRK13646 3 IRFDNVSYTY--QKgtpyehqAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTkdkyI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 71 LELRRRMGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGV 145
Cdd:PRK13646 81 RPVRKRIGMVFQ----FPESqlfedTVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 146 ARALAADPQVLLMDEPFGALDPVTRgalQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:PRK13646 157 VSILAMNPDIIVLDEPTAGLDPQSK---RQVMRLLKSLQtdeNKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL 233
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
2-224 |
1.36e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 127.43 E-value: 1.36e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI-----RSLPVLELRRR 76
Cdd:PRK13645 12 VSYTYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanlkKIKEVKRLRKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAA 151
Cdd:PRK13645 92 IGLVFQ----FPEYqlfqeTIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAM 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:PRK13645 168 DGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
15-248 |
2.21e-34 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 126.39 E-value: 2.21e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIG--LFPHwTV 92
Cdd:PRK13647 19 KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLVFQDPDdqVFSS-TV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 93 AQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGA 172
Cdd:PRK13647 98 WDDVAFGPVNMGLDKDEVERRVEEALKAVRMW-DFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQET 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 173 LQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPlEMLTAP----ANDF-----VQAFFGRSELGVR 243
Cdd:PRK13647 177 LMEILDRLHN-QGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK-SLLTDEdiveQAGLrlplvAQIFEDLPELGQS 254
|
....*
gi 581977852 244 LLSLR 248
Cdd:PRK13647 255 KLPLT 259
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-214 |
3.32e-34 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 122.54 E-value: 3.32e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElRRRMGyai 81
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRD-ARRAG--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 qsiglfphwtvaqnIATVpqlqkwsrsriddrteelmallgldvnlrhrypHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03216 77 --------------IAMV---------------------------------YQLSVGERQMVEIARALARNARLLILDEP 109
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 162 FGALDPVTRGALqqeMTRIHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:cd03216 110 TAALTPAEVERL---FKVIRRLraQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-225 |
4.34e-34 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 126.46 E-value: 4.34e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlPVLELRRRMGYAI 81
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPS-RARHARQRVGVVP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYpHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:PRK13537 87 QFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKV-GELSGGMKRRLTLARALVNDPDVLVLDEP 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 162 FGALDPVTRGALQQemtRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:PRK13537 166 TTGLDPQARHLMWE---RLRSLLarGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-236 |
8.17e-34 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 124.50 E-value: 8.17e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD-----SGVIRFAGEEIRS--LPVLEL 73
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNpevtiTGSIVYNGHNIYSprTDTVDL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAIQSIGLFPhWTVAQNIATVPQLQKW-SRSRIDDRTEElmALLGLDV-----NLRHRYPHQLSGGQQQRVGVAR 147
Cdd:PRK14239 85 RKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIkDKQVLDEAVEK--SLKGASIwdevkDRLHDSALGLSGGQQQRVCIAR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:PRK14239 162 VLATSPKIILLDEPTSALDPISAGKIEETLLGLKD--DYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPK 239
|
250
....*....|...
gi 581977852 228 N----DFVQAFFG 236
Cdd:PRK14239 240 HketeDYISGKFG 252
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
3-222 |
8.86e-34 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 123.40 E-value: 8.86e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 3 EFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYAI 81
Cdd:TIGR03410 2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAgIAYVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLgldVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:TIGR03410 82 QGREIFPRLTVEENLLTGLAALPRRSRKIPDEIYELFPVL---KEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 162 FGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:TIGR03410 159 TEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-217 |
9.61e-34 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 123.25 E-value: 9.61e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQK----AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvLELRRR 76
Cdd:cd03266 1 MITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEP-AEARRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:cd03266 80 LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGME-ELLDRRVGGFSTGMRQKVAIARALVHDPPVL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 157 LMDEPFGALDPVTRGALqQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03266 159 LLDEPTTGLDVMATRAL-REFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-226 |
4.53e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 122.99 E-value: 4.53e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:PRK13652 3 LIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIG--LFPHwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK13652 83 VFQNPDdqIFSP-TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLV 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK13652 161 LDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-222 |
4.82e-33 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 122.57 E-value: 4.82e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRRM 77
Cdd:PRK11831 7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSrsrLYTVRKRM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHWTVAQNIAtVPQLQKWSRSRIDDRTEELMALLGldVNLR---HRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:PRK11831 87 SMLFQSGALFTDMNVFDNVA-YPLREHTQLPAPLLHSTVMMKLEA--VGLRgaaKLMPSELSGGMARRAALARAIALEPD 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 155 VLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:PRK11831 164 LIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
2-223 |
5.02e-33 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 121.57 E-value: 5.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG--AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:cd03251 1 VEFKNVTFRYPgdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFpHWTVAQNIA----TVPQLQKWSRSRIDDRTEELMAL-LGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQ 154
Cdd:cd03251 81 VSQDVFLF-NDTVAENIAygrpGATREEVEEAARAANAHEFIMELpEGYDTVIGER-GVKLSGGQRQRIAIARALLKDPP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 155 VLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:cd03251 159 ILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRL-STIENADRIVVLEDGKIVERGTHEELL 224
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
34-221 |
6.02e-33 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 124.60 E-value: 6.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 34 GTSGSGKSTTLKMINRLVEHDSGVIRFAG------EEIRSLPVlElRRRMGYAIQSIGLFPHWTVAQNiatvpqLQ---- 103
Cdd:PRK11144 31 GRSGAGKTSLINAISGLTRPQKGRIVLNGrvlfdaEKGICLPP-E-KRRIGYVFQDARLFPHYKVRGN------LRygma 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 104 KWSRSRIDDrteeLMALLGLDVNLRhRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALD-PVTRgalqQEMTRIHR 182
Cdd:PRK11144 103 KSMVAQFDK----IVALLGIEPLLD-RYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKR----ELLPYLER 173
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 581977852 183 LLGRT---IVLVTHDIDEALRLAEHLVLMDGGEVVQQGtPLE 221
Cdd:PRK11144 174 LAREInipILYVSHSLDEILRLADRVVVLEQGKVKAFG-PLE 214
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
2-223 |
1.48e-32 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 120.41 E-value: 1.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVskTFG---AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:cd03253 1 IEFENV--TFAydpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFpHWTVAQNI------ATVPQLQKWSR-SRIDDRTEELMAllGLDVNLRHRyPHQLSGGQQQRVGVARALAA 151
Cdd:cd03253 79 VVPQDTVLF-NDTIGYNIrygrpdATDEEVIEAAKaAQIHDKIMRFPD--GYDTIVGER-GLKLSGGEKQRVAIARAILK 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHdidealRL-----AEHLVLMDGGEVVQQGTPLEML 223
Cdd:cd03253 155 NPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAH------RLstivnADKIIVLKDGRIVERGTHEELL 223
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
12-233 |
1.52e-32 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 125.95 E-value: 1.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRL----VEHDSGVIRFAGEEIRSLPVLELRR----RMGYAIQ- 82
Cdd:COG4172 21 GTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLlpdpAAHPSGSILFDGQDLLGLSERELRRirgnRIAMIFQe 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 -SIGLFPHWTVAQNIATVPQL-QKWSRSRIDDRTEELMALLGLD--VNLRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:COG4172 101 pMTSLNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPdpERRLDAYPHQLSGGQRQRVMIAMALANEPDLLIA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 159 DEPFGALDpVTRGA--------LQQEMtrihrllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDF 230
Cdd:COG4172 181 DEPTTALD-VTVQAqildllkdLQREL-------GMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELFAAPQHPY 252
|
...
gi 581977852 231 VQA 233
Cdd:COG4172 253 TRK 255
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
2-226 |
1.76e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 121.45 E-value: 1.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK--AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLV---EHDSGVIRFAGEEIRSLPVLELRRR 76
Cdd:PRK13640 6 VEFKHVSFTYPDSKkpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLTAKTVWDIREK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSI-GLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:PRK13640 86 VGIVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGM-LDYIDSEPANLSGGQKQRVAIAGILAVEPKI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEAlRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK13640 165 IILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKV 234
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-211 |
1.91e-32 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 119.85 E-value: 1.91e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF------GAQ-KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINR---------LVEHDSGVIRFAGEE 64
Cdd:COG4778 4 LLEVENLSKTFtlhlqgGKRlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGnylpdsgsiLVRHDGGWVDLAQAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 65 IRSlpVLELRRR-MGYaiqsiglfphwtVAQNIATVPQL------------QKWSRSRIDDRTEELMALLGLDVNLRHRY 131
Cdd:COG4778 84 PRE--ILALRRRtIGY------------VSQFLRVIPRVsaldvvaeplleRGVDREEARARARELLARLNLPERLWDLP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 132 PHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQemtRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMD 209
Cdd:COG4778 150 PATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVE---LIEEAKarGTAIIGIFHDEEVREAVADRVVDVT 226
|
..
gi 581977852 210 GG 211
Cdd:COG4778 227 PF 228
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
2-226 |
2.40e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 121.47 E-value: 2.40e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGA-----QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR----SLPVLE 72
Cdd:PRK13641 3 IKFENVDYIYSPgtpmeKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgNKNLKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQ--SIGLFPHwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALA 150
Cdd:PRK13641 83 LRKKVSLVFQfpEAQLFEN-TVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMA 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 151 ADPQVLLMDEPFGALDPVTRgalqQEMTRI---HRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK13641 162 YEPEILCLDEPAAGLDPEGR----KEMMQLfkdYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
21-224 |
3.11e-32 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 119.69 E-value: 3.11e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 21 NLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlELRRRMGYAIQSIGLFPHWTVAQNIA--T 98
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTP--PSRRPVSMLFQENNLFSHLTVAQNIGlgL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 VPQLQKWSRSRidDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPvtrgALQQEM- 177
Cdd:PRK10771 97 NPGLKLNAAQR--EKLHAIARQMGIE-DLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDP----ALRQEMl 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 581977852 178 ---TRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:PRK10771 170 tlvSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLS 219
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-222 |
5.57e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 120.19 E-value: 5.57e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIE-----FSHVSKTFGAQK-AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP-VLEL 73
Cdd:PRK13633 4 MIKcknvsYKYESNEESTEKlALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEnLWDI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAIQ--------SIglfphwtVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRyPHQLSGGQQQRVGV 145
Cdd:PRK13633 84 RNKAGMVFQnpdnqivaTI-------VEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHA-PHLLSGGQKQRVAI 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 146 ARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTPLEM 222
Cdd:PRK13633 156 AGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEI 231
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
17-232 |
6.18e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 120.22 E-value: 6.18e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSI-GLFPHWTVAQN 95
Cdd:PRK13650 23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHKIGMVFQNPdNQFVGATVEDD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 96 IATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQ 175
Cdd:PRK13650 103 VAFGLENKGIPHEEMKERVNEALELVGMQ-DFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIK 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 176 EMTRIHRLLGRTIVLVTHDIDEaLRLAEHLVLMDGGEVVQQGTPLEmLTAPANDFVQ 232
Cdd:PRK13650 182 TIKGIRDDYQMTVISITHDLDE-VALSDRVLVMKNGQVESTSTPRE-LFSRGNDLLQ 236
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
7-213 |
8.36e-32 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 119.01 E-value: 8.36e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRfAGeeirSLPVLELRRRMGYAIQSIGL 86
Cdd:PRK11247 18 VSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL-AG----TAPLAEAREDTRLMFQDARL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 87 FPHWTVAQNIATvpQLQ-KWSrsridDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGAL 165
Cdd:PRK11247 93 LPWKKVIDNVGL--GLKgQWR-----DAALQALAAVGLA-DRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGAL 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 581977852 166 DPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:PRK11247 165 DALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
6-223 |
8.49e-32 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 118.84 E-value: 8.49e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 6 HVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYAIQSI 84
Cdd:PRK10895 8 NLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRgIGYLPQEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 GLFPHWTVAQNIATVPQLQK-WSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFG 163
Cdd:PRK10895 88 SIFRRLSVYDNLMAVLQIRDdLSAEQREDRANELMEEFHIE-HLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 164 ALDPVTRGALQQEMTRIhRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK10895 167 GVDPISVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIL 225
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
8-227 |
1.10e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 120.34 E-value: 1.10e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 8 SKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIR----FAGEEIRSLPVL------------ 71
Cdd:PRK13631 33 EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQvgdiYIGDKKNNHELItnpyskkiknfk 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 72 ELRRRMGYAIQsiglFPHW-----TVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVA 146
Cdd:PRK13631 113 ELRRRVSMVFQ----FPEYqlfkdTIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIA 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 147 RALAADPQVLLMDEPFGALDPvtrgALQQEMTRI---HRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK13631 189 GILAIQPEILIFDEPTAGLDP----KGEHEMMQLildAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIF 264
|
....
gi 581977852 224 TAPA 227
Cdd:PRK13631 265 TDQH 268
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
18-211 |
1.22e-31 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 117.84 E-value: 1.22e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 18 NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLE---LR-RRMGYAIQSIGLFPHWTVA 93
Cdd:TIGR02211 22 KGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNErakLRnKKLGFIYQFHHLLPDFTAL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 94 QNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGAL 173
Cdd:TIGR02211 102 ENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHR-PSELSGGERQRVAIARALVNQPSLVLADEPTGNLDNNNAKII 180
|
170 180 190
....*....|....*....|....*....|....*...
gi 581977852 174 QQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGG 211
Cdd:TIGR02211 181 FDLMLELNRELNTSFLVVTHDLELAKKLDRVLEMKDGQ 218
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-214 |
1.93e-31 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 122.83 E-value: 1.93e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEE--IRSlPVLELRRRMG 78
Cdd:COG3845 5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPvrIRS-PRDAIALGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHWTVAQNIA---TVPQLQKWSRSRIDDRTEELMALLGLDVNLrHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:COG3845 84 MVHQHFMLVPNLTVAENIVlglEPTKGGRLDRKAARARIRELSERYGLDVDP-DAKVEDLSVGEQQRVEILKALYRGARI 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 156 LLMDEPFGALDPvtrgalqQE----MTRIHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:COG3845 163 LILDEPTAVLTP-------QEadelFEILRRLaaEGKSIIFITHKLREVMAIADRVTVLRRGKVV 220
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
2-217 |
2.01e-31 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 117.11 E-value: 2.01e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLpvlelrRRMGY 79
Cdd:TIGR03740 1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWtrKDL------HKIGS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDdrteELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:TIGR03740 75 LIESPPLYENLTARENLKVHTTLLGLPDSRID----EVLNIVDLT-NTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILD 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 160 EPFGALDPVTrgalQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:TIGR03740 150 EPTNGLDPIG----IQELRELIRSFpeqGITVILSSHILSEVQQLADHIGIISEGVLGYQG 206
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-208 |
2.15e-31 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 122.78 E-value: 2.15e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHwTVAQNI------ATVPQLQK-WSRSRIDDRTEELMAllGLDVNLRHRyPHQLSGGQQQRVGVARALAADP 153
Cdd:TIGR02857 402 PQHPFLFAG-TIAENIrlarpdASDAEIREaLERAGLDEFVAALPQ--GLDTPIGEG-GAGLSGGQAQRLALARAFLRDA 477
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 154 QVLLMDEPFGALDPVTrgalQQEMTRIHRLL--GRTIVLVTHDiDEALRLAEHLVLM 208
Cdd:TIGR02857 478 PLLLLDEPTAHLDAET----EAEVLEALRALaqGRTVLLVTHR-LALAALADRIVVL 529
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
15-198 |
2.17e-31 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 115.98 E-value: 2.17e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI----RSLpvLELRRRMGYAIQSIG--LFP 88
Cdd:TIGR01166 6 EVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLdysrKGL--LERRQRVGLVFQDPDdqLFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 89 HwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPv 168
Cdd:TIGR01166 84 A-DVDQDVAFGPLNLGLSEAEVERRVREALTAVGAS-GLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDP- 160
|
170 180 190
....*....|....*....|....*....|..
gi 581977852 169 tRGAlQQEMTRIHRLL--GRTIVLVTHDIDEA 198
Cdd:TIGR01166 161 -AGR-EQMLAILRRLRaeGMTVVISTHDVDLA 190
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-223 |
2.44e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 119.04 E-value: 2.44e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQ-----KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRF---------AGEEIRS 67
Cdd:PRK13651 3 IKVKNIVKIFNKKlptelKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkdeknkkKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 68 LP---------------VLELRRRMGYAIQ--SIGLFPHwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHR 130
Cdd:PRK13651 83 VLeklviqktrfkkikkIKEIRRRVGVVFQfaEYQLFEQ-TIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDESYLQR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 131 YPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVtrGAlqQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVL 207
Cdd:PRK13651 162 SPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQ--GV--KEILEIFDNLnkqGKTIILVTHDLDNVLEWTKRTIF 237
|
250
....*....|....*.
gi 581977852 208 MDGGEVVQQGTPLEML 223
Cdd:PRK13651 238 FKDGKIIKDGDTYDIL 253
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-226 |
3.03e-31 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 120.72 E-value: 3.03e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNI--ATVPQLQKWSRSRIDDRT--EELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:PRK09536 83 PQDTSLSFEFDVRQVVemGRTPHRSRFDTWTETDRAavERAMERTGVA-QFADRPVTSLSGGERQRVLLARALAQATPVL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 157 LMDEPFGALDpVTRGALQQEMTRihRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK09536 162 LLDEPTASLD-INHQVRTLELVR--RLVddGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTAD 230
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-195 |
3.64e-31 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 116.51 E-value: 3.64e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLE---LRRR 76
Cdd:PRK10908 1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREvpfLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGL-LDKAKNFPIQLSGGEQQRVGIARAVVNKPAVL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 581977852 157 LMDEPFGALDpvtrGALQQEMTRIHRLLGR---TIVLVTHDI 195
Cdd:PRK10908 160 LADEPTGNLD----DALSEGILRLFEEFNRvgvTVLMATHDI 197
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
2-225 |
5.34e-31 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 116.43 E-value: 5.34e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAV--NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:cd03252 1 ITFEHVRFRYKPDGPVilDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHwTVAQNIATVPQLQKWSR----SRIDDRTEELMAL-LGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQ 154
Cdd:cd03252 81 VLQENVLFNR-SIRDNIALADPGMSMERvieaAKLAGAHDFISELpEGYDTIVGEQ-GAGLSGGQRQRIAIARALIHNPR 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 155 VLLMDEPFGALDPVTRGALQQEMTRIhrLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:cd03252 159 ILIFDEATSALDYESEHAIMRNMHDI--CAGRTVIIIAHRL-STVKNADRIIVMEKGRIVEQGSHDELLAE 226
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
16-226 |
5.83e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 117.49 E-value: 5.83e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI----RSLpvLELRRRMGYAIQSIG--LF-P 88
Cdd:PRK13639 17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIkydkKSL--LEVRKTVGIVFQNPDdqLFaP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 89 hwTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPv 168
Cdd:PRK13639 95 --TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGME-GFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDP- 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 169 tRGALQqemtrIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK13639 171 -MGASQ-----IMKLLydlnkeGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-228 |
8.69e-31 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 116.67 E-value: 8.69e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDS-----GVIRFAGEEI--RSLPVLELR 74
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIyeRRVNLNRLR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 RRMGYAIQSIGLFPhWTVAQNIATVPQLQKW-SRSRIDDRTEElmALLGLDV-----NLRHRYPHQLSGGQQQRVGVARA 148
Cdd:PRK14258 88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWrPKLEIDDIVES--ALKDADLwdeikHKIHKSALDLSGGQQQRLCIARA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQqemTRIHRLLGR---TIVLVTHDIDEALRLAEHLVLMDG-----GEVVQQGTPL 220
Cdd:PRK14258 165 LAVKPKVLLMDEPCFGLDPIASMKVE---SLIQSLRLRselTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTK 241
|
....*...
gi 581977852 221 EMLTAPAN 228
Cdd:PRK14258 242 KIFNSPHD 249
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-232 |
1.28e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 116.73 E-value: 1.28e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLN---LHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRM 77
Cdd:PRK13642 4 ILEVENLVFKYEKESDVNQLNgvsFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSI-GLFPHWTVAQNIATVPQLQKWSRSRIDDRTEElmALLGLD-VNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:PRK13642 84 GMVFQNPdNQFVGATVEDDVAFGMENQGIPREEMIKRVDE--ALLAVNmLDFKTREPARLSGGQKQRVAVAGIIALRPEI 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTPLEMLtAPANDFVQ 232
Cdd:PRK13642 162 IILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF-ATSEDMVE 236
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
11-208 |
1.46e-30 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 113.87 E-value: 1.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 11 FGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeirslpvlelRRRMGYAIQSIGL---F 87
Cdd:NF040873 2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAG-----------GARVAYVPQRSEVpdsL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 88 PhWTVAQNIA--TVPQLQKWSRSRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFG 163
Cdd:NF040873 71 P-LTVRDLVAmgRWARRGLWRRLTRDDRaaVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 581977852 164 ALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEAlRLAEHLVLM 208
Cdd:NF040873 149 GLDAESRERIIALLAEEHA-RGATVVVVTHDLELV-RRADPCVLL 191
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
15-233 |
2.10e-30 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 117.11 E-value: 2.10e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGyAIQSI------GLFP 88
Cdd:PRK15079 35 KAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRS-DIQMIfqdplaSLNP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 89 HWTVAQNIAT-----VPQLqkwSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFG 163
Cdd:PRK15079 114 RMTIGEIIAEplrtyHPKL---SRQEVKDRVKAMMLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVS 190
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 164 ALDpVTRGA--------LQQEMtrihrllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQA 233
Cdd:PRK15079 191 ALD-VSIQAqvvnllqqLQREM-------GLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTKA 260
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
16-223 |
2.78e-30 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 115.72 E-value: 2.78e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLPVLELRRRMGYAIQSIG--LFPHwT 91
Cdd:PRK13636 21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdySRKGLMKLRESVGMVFQDPDnqLFSA-S 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 92 VAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRG 171
Cdd:PRK13636 100 VYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIE-HLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVS 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 172 ALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK13636 179 EIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-223 |
2.86e-29 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 116.83 E-value: 2.86e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-----GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRF-AGEEIRSL--PVLE 72
Cdd:TIGR03269 279 IIKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrVGDEWVDMtkPGPD 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRR----MGYAIQSIGLFPHWTVAQNIATVPQLQkwsrsrIDDRTEELMALLGLDV---------NLRHRYPHQLSGGQ 139
Cdd:TIGR03269 359 GRGRakryIGILHQEYDLYPHRTVLDNLTEAIGLE------LPDELARMKAVITLKMvgfdeekaeEILDKYPDELSEGE 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 140 QQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTP 219
Cdd:TIGR03269 433 RHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDP 512
|
....
gi 581977852 220 LEML 223
Cdd:TIGR03269 513 EEIV 516
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-258 |
3.07e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 112.77 E-value: 3.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVL-ELRRRMG 78
Cdd:PRK13644 1 MIRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLqGIRKLVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGL-FPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK13644 81 IVFQNPETqFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLE-KYRHRSPKTLSGGQGQCVALAGILTMEPECLI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEaLRLAEHLVLMDGGEVVQQGTPLEMLTAPAndfvqaffgR 237
Cdd:PRK13644 160 FDEVTSMLDPDSGIAVLERIKKLHE-KGKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVS---------L 228
|
250 260
....*....|....*....|.
gi 581977852 238 SELGVRLLSLRSVGDYVRRHE 258
Cdd:PRK13644 229 QTLGLTPPSLIELAENLKMHG 249
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
16-237 |
4.46e-29 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 111.31 E-value: 4.46e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVehDSGVIRFAGE-EIRSLPVLELR---RRMGYAIQS-IGLF-PH 89
Cdd:TIGR02770 1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLL--PPGLTQTSGEiLLDGRPLLPLSirgRHIATIMQNpRTAFnPL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 90 WTVA-QNIATVPQLQKWSRSRIDDRTEELMAllgldVNLRH------RYPHQLSGGQQQRVGVARALAADPQVLLMDEPF 162
Cdd:TIGR02770 79 FTMGnHAIETLRSLGKLSKQARALILEALEA-----VGLPDpeevlkKYPFQLSGGMLQRVMIALALLLEPPFLIADEPT 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 163 GALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFGR 237
Cdd:TIGR02770 154 TDLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSA 228
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
21-217 |
4.71e-29 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 110.72 E-value: 4.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 21 NLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlELRRRMGYAIQSIGLFPHWTVAQNIA--T 98
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLA--PYQRPVSMLFQENNLFAHLTVRQNIGlgL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 VPQLQKWSRSRidDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPvtrgALQQEMT 178
Cdd:TIGR01277 96 HPGLKLNAEQQ--EKVVDAAQQVGIA-DYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDP----LLREEML 168
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 581977852 179 RIHRLLG----RTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:TIGR01277 169 ALVKQLCserqRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
11-236 |
6.07e-29 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 111.62 E-value: 6.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 11 FGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHW 90
Cdd:PRK10253 17 YGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIAT-----VPQLQKWsRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGAL 165
Cdd:PRK10253 97 TVQELVARgryphQPLFTRW-RKEDEEAVTKAMQATGI-THLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWL 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 166 DPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTApanDFVQAFFG 236
Cdd:PRK10253 175 DISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTA---ELIERIYG 242
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-223 |
9.36e-29 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 113.00 E-value: 9.36e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElRRRMGYAI 81
Cdd:PRK13536 42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLA-RARIGVVP 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPhQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:PRK13536 121 QFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVS-DLSGGMKRRLTLARALINDPQLLILDEP 199
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 162 FGALDPVTRGALQQemtRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK13536 200 TTGLDPHARHLIWE---RLRSLLarGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALI 260
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
2-232 |
1.87e-28 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 110.31 E-value: 1.87e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF---------GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI------- 65
Cdd:COG4167 5 LEVRNLSKTFkyrtglfrrQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLeygdyky 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 66 RSLPVlelrrRMGYAIQSIGLFPHWTVAQnIATVPqLQ---KWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQR 142
Cdd:COG4167 85 RCKHI-----RMIFQDPNTSLNPRLNIGQ-ILEEP-LRlntDLTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQKQR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 143 VGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:COG4167 158 VALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEV 237
|
250
....*....|
gi 581977852 223 LTAPANDFVQ 232
Cdd:COG4167 238 FANPQHEVTK 247
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-237 |
2.30e-28 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 114.82 E-value: 2.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF----GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSL---PVLEL 73
Cdd:PRK10535 4 LLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLdadALAQL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRR-MGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRyPHQLSGGQQQRVGVARALAAD 152
Cdd:PRK10535 84 RREhFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQ-PSQLSGGQQQRVSIARALMNG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 153 PQVLLMDEPFGALDPVTRgalQQEMTRIHRLL--GRTIVLVTHDID---EALRLAE----HLVLMDGGEVVQQGTPLEML 223
Cdd:PRK10535 163 GQVILADEPTGALDSHSG---EEVMAILHQLRdrGHTVIIVTHDPQvaaQAERVIEirdgEIVRNPPAQEKVNVAGGTEP 239
|
250
....*....|....
gi 581977852 224 TAPANDFVQAFFGR 237
Cdd:PRK10535 240 VVNTASGWRQFVSG 253
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
19-210 |
3.09e-28 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 109.13 E-value: 3.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPV---LELR-RRMGYAIQSIGLFPHWTVAQ 94
Cdd:PRK11629 27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSaakAELRnQKLGFIYQFHHLLPDFTALE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 95 NIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQ 174
Cdd:PRK11629 107 NVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHR-PSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIF 185
|
170 180 190
....*....|....*....|....*....|....*.
gi 581977852 175 QEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDG 210
Cdd:PRK11629 186 QLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDG 221
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
11-226 |
3.92e-28 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 109.80 E-value: 3.92e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 11 FGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGViRFAGEEI---RSL----PVLELRRRMGYAIQS 83
Cdd:PRK14271 31 FAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGY-RYSGDVLlggRSIfnyrDVLEFRRRVGMLFQR 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRY---PHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:PRK14271 110 PNPFPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLsdsPFRLSGGQQQLLCLARTLAVNPEVLLLDE 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK14271 190 PTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSP 253
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-214 |
5.29e-28 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 109.02 E-value: 5.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGA-----QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRR 75
Cdd:COG1101 1 MLELKNLSKTFNPgtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQ--SIGLFPHWTVAQNIATVPQLQK---WSRSRIDDRTE---ELMALLGLdvNLRHRYPHQ---LSGGQQQRVG 144
Cdd:COG1101 81 YIGRVFQdpMMGTAPSMTIEENLALAYRRGKrrgLRRGLTKKRRElfrELLATLGL--GLENRLDTKvglLSGGQRQALS 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 145 VARALAADPQVLLMDEPFGALDPVTRG---ALQQEMTRIHRLlgrTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:COG1101 159 LLMATLTKPKLLLLDEHTAALDPKTAAlvlELTEKIVEENNL---TTLMVTHNMEQALDYGNRLIMMHEGRII 228
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
7-224 |
9.58e-28 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 108.62 E-value: 9.58e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEeirslPVLELRRRMGYAIQ---- 82
Cdd:PRK10419 18 LSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGE-----PLAKLNRAQRKAFRrdiq 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 -----SIGLF-PHWTVAQNIAT-VPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:PRK10419 93 mvfqdSISAVnPRKTVREIIREpLRHLLSLDKAERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKL 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:PRK10419 173 LILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGDKLT 241
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
20-226 |
9.70e-28 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 108.72 E-value: 9.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 20 LNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWTVAQNIAT- 98
Cdd:PRK10575 30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVRELVAIg 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 -VPQLQKWSRSRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALD---PVTRGA 172
Cdd:PRK10575 110 rYPWHGALGRFGAADRekVEEAISLVGLK-PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDiahQVDVLA 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 581977852 173 LQQEMTRIHrllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK10575 189 LVHRLSQER---GLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGE 239
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
9-232 |
1.76e-27 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 111.72 E-value: 1.76e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 9 KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEhDSGVIRFAGEEIRSL---PVLELRRRMGYAIQ--S 83
Cdd:PRK15134 294 RTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQPLHNLnrrQLLPVRHRIQVVFQdpN 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHWTVAQNIAT-----VPQLQKWSRsriDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:PRK15134 373 SSLNPRLNVLQIIEEglrvhQPTLSAAQR---EQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIIL 449
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 159 DEPFGALDPVTRG---ALQQEMTRIHRLlgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQ 232
Cdd:PRK15134 450 DEPTSSLDKTVQAqilALLKSLQQKHQL---AYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTR 523
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-197 |
1.93e-27 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 106.72 E-value: 1.93e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYC 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHwTVAQNIATVPQLQKWSRSRidDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:PRK10247 87 AQTPTLFGD-TVYDNLIFPWQIRNQQPDP--AIFLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDE 163
|
170 180 190
....*....|....*....|....*....|....*..
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDE 197
Cdd:PRK10247 164 ITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE 200
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
15-217 |
2.06e-27 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 106.59 E-value: 2.06e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD---SGVIRFAGEEIRSLpvlELRRRMGYAIQSIGLFPHWT 91
Cdd:cd03234 21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQPRKPD---QFQKCVAYVRQDDILLPGLT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 92 VAQNIATVPQ--LQKWSRSRIDDRTEELMALLGL-DVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPV 168
Cdd:cd03234 98 VRETLTYTAIlrLPRKSSDAIRKKRVEDVLLRDLaLTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSF 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 581977852 169 TRGALQQEMTRIHRlLGRTIVLVTHDI-DEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03234 178 TALNLVSTLSQLAR-RNRIVILTIHQPrSDLFRLFDRILLLSSGEIVYSG 226
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
17-213 |
2.85e-27 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 104.61 E-value: 2.85e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwTVAQNI 96
Cdd:cd03246 18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLPQDDELFSG-SIAENI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 97 atvpqlqkwsrsriddrteelmallgldvnlrhryphqLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQE 176
Cdd:cd03246 97 --------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQA 138
|
170 180 190
....*....|....*....|....*....|....*..
gi 581977852 177 MTRIhRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEV 213
Cdd:cd03246 139 IAAL-KAAGATRIVIAHRP-ETLASADRILVLEDGRV 173
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
16-220 |
8.02e-27 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 110.87 E-value: 8.02e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlPVLELRRRMGYAIQSIGLFPHWTVAQN 95
Cdd:TIGR01257 945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET-NLDAVRQSLGMCPQHNILFHHLTVAEH 1023
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 96 IATVPQLQKWSRsriDDRTEELMALLGlDVNLRHRYPHQ---LSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGA 172
Cdd:TIGR01257 1024 ILFYAQLKGRSW---EEAQLEMEAMLE-DTGLHHKRNEEaqdLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRS 1099
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 581977852 173 LQQEMTRIHRllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPL 220
Cdd:TIGR01257 1100 IWDLLLKYRS--GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPL 1145
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-225 |
9.50e-27 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 105.16 E-value: 9.50e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQK----------------------AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVI 58
Cdd:COG1134 4 MIEVENVSKSYRLYHepsrslkelllrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 59 RFAGeEIRSLpvLELrrrmgyaiqSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMAL--LG--LDVNLRHrYphq 134
Cdd:COG1134 84 EVNG-RVSAL--LEL---------GAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFaeLGdfIDQPVKT-Y--- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 lSGGQQQRVGVARALAADPQVLLMDEPFGALDPvtrgALQQE-MTRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGG 211
Cdd:COG1134 148 -SSGMRARLAFAVATAVDPDILLVDEVLAVGDA----AFQKKcLARIRELResGRTVIFVSHSMGAVRRLCDRAIWLEKG 222
|
250
....*....|....
gi 581977852 212 EVVQQGTPLEMLTA 225
Cdd:COG1134 223 RLVMDGDPEEVIAA 236
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-222 |
1.33e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 105.60 E-value: 1.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKA--VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:PRK13648 7 IIVFKNVSFQYQSDASftLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSI-GLFPHWTVAQNIA------TVPQlqkwsrsriDDRTEELMALLGlDVNLRHRY---PHQLSGGQQQRVGVARA 148
Cdd:PRK13648 87 IVFQNPdNQFVGSIVKYDVAfglenhAVPY---------DEMHRRVSEALK-QVDMLERAdyePNALSGGQKQRVAIAGV 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTPLEM 222
Cdd:PRK13648 157 LALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEI 229
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
32-210 |
2.16e-26 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 104.09 E-value: 2.16e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 32 LIGTSGSGKSTTLKMINRLVEHDSGVIRFAG-------EEIRSlpvlELR-RRMGYAIQSIGLFPHWTVAQNIATVPQLQ 103
Cdd:PRK10584 41 LIGESGSGKSTLLAILAGLDDGSSGEVSLVGqplhqmdEEARA----KLRaKHVGFVFQSFMLIPTLNALENVELPALLR 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 104 KWSRSRIDDRTEELMALLGLDVNLRHrYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRL 183
Cdd:PRK10584 117 GESSRQSRNGAKALLEQLGLGKRLDH-LPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNRE 195
|
170 180
....*....|....*....|....*..
gi 581977852 184 LGRTIVLVTHDIDEALRLAEHLVLMDG 210
Cdd:PRK10584 196 HGTTLILVTHDLQLAARCDRRLRLVNG 222
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-203 |
4.17e-26 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 104.09 E-value: 4.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRL--------VEhdsGVIRFAGEEIRSLPV--L 71
Cdd:PRK14243 11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLndlipgfrVE---GKVTFHGKNLYAPDVdpV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 72 ELRRRMGYAIQSIGLFPHwTVAQNIATVPQLQKWsRSRIDDRTEELM--ALLGLDVNLRHRYPHQ-LSGGQQQRVGVARA 148
Cdd:PRK14243 88 EVRRRIGMVFQKPNPFPK-SIYDNIAYGARINGY-KGDMDELVERSLrqAALWDEVKDKLKQSGLsLSGGQQQRLCIARA 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMtriHRLLGR-TIVLVTHDIDEALRLAE 203
Cdd:PRK14243 166 IAVQPEVILMDEPCSALDPISTLRIEELM---HELKEQyTIIIVTHNMQQAARVSD 218
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-218 |
5.16e-26 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 103.94 E-value: 5.16e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGV---IRFAGEEIR-----SLPVLE 72
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAgshIELLGRTVQregrlARDIRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQSIGLFPHWTVAQNI-----ATVPQLQ---KWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVG 144
Cdd:PRK09984 84 SRANTGYIFQQFNLVNRLSVLENVligalGSTPFWRtcfSWFTREQKQRALQALTRVGM-VHFAHQRVSTLSGGQQQRVA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 145 VARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGT 218
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGS 236
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
6-214 |
6.06e-26 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 101.95 E-value: 6.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 6 HVSKTFG-AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeiRSLPVLELRRRMGYAIQSI 84
Cdd:cd03226 4 NISFSYKkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNG---KPIKAKERRKSIGYVMQDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 G--LFPHwTVAQNIA-TVPQLqkwsrSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03226 81 DyqLFTD-SVREELLlGLKEL-----DAGNEQAETVLKDLDLY-ALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEP 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 162 FGALDPvtrgalqQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:cd03226 154 TSGLDY-------KNMERVGELIrelaaqGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
12-225 |
7.87e-26 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 107.05 E-value: 7.87e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwT 91
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIGYLPQDVELFPG-T 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 92 VAQNIAtvpqlqkwsrsRIDDRTE--------------ELMALL--GLDVNLRHRyPHQLSGGQQQRVGVARALAADPQV 155
Cdd:TIGR01842 408 VAENIA-----------RFGENADpekiieaaklagvhELILRLpdGYDTVIGPG-GATLSGGQRQRIALARALYGDPKL 475
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIhRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:TIGR01842 476 VVLDEPNSNLDEEGEQALANAIKAL-KARGITVVVITHRP-SLLGCVDKILVLQDGRIARFGERDEVLAK 543
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
12-227 |
1.59e-25 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 106.37 E-value: 1.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAV-NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHw 90
Cdd:COG4618 342 GSKRPIlRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIGYLPQDVELFDG- 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIAtvpqlqkwsRSRIDDRTEELMA--LLGLD---VNLRHRY-------PHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:COG4618 421 TIAENIA---------RFGDADPEKVVAAakLAGVHemiLRLPDGYdtrigegGARLSGGQRQRIGLARALYGDPRLVVL 491
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 159 DEPFGALDPVTRGALQQEMTRIhRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTP---LEMLTAPA 227
Cdd:COG4618 492 DEPNSNLDDEGEAALAAAIRAL-KARGATVVVITHRP-SLLAAVDKLLVLRDGRVQAFGPRdevLARLARPA 561
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
12-233 |
3.59e-25 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 103.06 E-value: 3.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMI------NRLVEHDSgvIRFAGEEIRSLPVLELRRRMGYAIQSI- 84
Cdd:COG4170 18 GRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAIcgitkdNWHVTADR--FRWNGIDLLKLSPRERRKIIGREIAMIf 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 -----GLFPHWTV-AQNIATVPQLQ---KWSRsRIDDRTEELMALLgldvnlrHR------------YPHQLSGGQQQRV 143
Cdd:COG4170 96 qepssCLDPSAKIgDQLIEAIPSWTfkgKWWQ-RFKWRKKRAIELL-------HRvgikdhkdimnsYPHELTEGECQKV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 144 GVARALAADPQVLLMDEPFGALDPVTRgalqqemTRIHRLLGR-------TIVLVTHDIDEALRLAEHLVLMDGGEVVQQ 216
Cdd:COG4170 168 MIAMAIANQPRLLIADEPTNAMESTTQ-------AQIFRLLARlnqlqgtSILLISHDLESISQWADTITVLYCGQTVES 240
|
250
....*....|....*..
gi 581977852 217 GTPLEMLTAPANDFVQA 233
Cdd:COG4170 241 GPTEQILKSPHHPYTKA 257
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
15-255 |
6.73e-25 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 102.13 E-value: 6.73e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGV----IRFAGEEIRSLPVLELRRRMGYAIQSI------ 84
Cdd:PRK11022 21 RAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVmaekLEFNGQDLQRISEKERRNLVGAEVAMIfqdpmt 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 GLFPHWTVA-QNIATVPQLQKWSRSRIDDRTEELMALLG-------LDVnlrhrYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:PRK11022 101 SLNPCYTVGfQIMEAIKVHQGGNKKTRRQRAIDLLNQVGipdpasrLDV-----YPHQLSGGMSQRVMIAMAIACRPKLL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 157 LMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQAFFG 236
Cdd:PRK11022 176 IADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPYTQALLR 255
|
250 260
....*....|....*....|....*
gi 581977852 237 R----SELGVRLLSLRSV--GDYVR 255
Cdd:PRK11022 256 AlpefAQDKARLASLPGVvpGKYDR 280
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
4-212 |
1.08e-24 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 98.70 E-value: 1.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 4 FSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeirslpvlelrrRMGYAIQS 83
Cdd:cd03250 8 FTWDSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG-------------SIAYVSQE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 iglfPhW----TVAQNIAtvpqlqkWSRSRIDDRTEELMALLGLDVNLRhRYPHQ-----------LSGGQQQRVGVARA 148
Cdd:cd03250 75 ----P-WiqngTIRENIL-------FGKPFDEERYEKVIKACALEPDLE-ILPDGdlteigekginLSGGQKQRISLARA 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 149 LAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIdEALRLAEHLVLMDGGE 212
Cdd:cd03250 142 VYSDADIYLLDDPLSAVDAHVGRHIFENCILGLLLNNKTRILVTHQL-QLLPHADQIVVLDNGR 204
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
2-218 |
1.47e-24 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 103.50 E-value: 1.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK13657 335 VEFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAVV 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHwTVAQNIatvpqlqkwSRSRIDDRTEELMA--------------LLGLDVNLRHRyPHQLSGGQQQRVGVA 146
Cdd:PRK13657 415 FQDAGLFNR-SIEDNI---------RVGRPDATDEEMRAaaeraqahdfierkPDGYDTVVGER-GRQLSGGERQRLAIA 483
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 147 RALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGT 218
Cdd:PRK13657 484 RALLKDPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAHRL-STVRNADRILVFDNGRVVESGS 552
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
2-217 |
3.02e-24 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 97.24 E-value: 3.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAV-NDLNLHFREGSFSVLIGTSGSGKSTTLKMIN--RLVEHDSGVIRFAGeeiRSLPVLELRRRMG 78
Cdd:cd03213 9 LTVTVKSSPSKSGKQLlKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrRTGLGVSGEVLING---RPLDKRSFRKIIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHWTVAQNiatvpqlqkwsrsriddrteelmalLGLDVNLRhryphQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:cd03213 86 YVPQDDILHPTLTVRET-------------------------LMFAAKLR-----GLSGGERKRVSIALELVSNPSLLFL 135
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 159 DEPFGALDPVTrgALQ-QEMTRIHRLLGRTIVLVTHDI-DEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03213 136 DEPTSGLDSSS--ALQvMSLLRRLADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
14-232 |
3.30e-24 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 102.48 E-value: 3.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 14 QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRL-----VEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSI---- 84
Cdd:PRK15134 22 RTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLlpsppVVYPSGDIRFHGESLLHASEQTLRGVRGNKIAMIfqep 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 --GLFPHWTVAQNIATVPQLQKWSRsRIDDRTEelmALLGLD-VNLRHR------YPHQLSGGQQQRVGVARALAADPQV 155
Cdd:PRK15134 102 mvSLNPLHTLEKQLYEVLSLHRGMR-REAARGE---ILNCLDrVGIRQAakrltdYPHQLSGGERQRVMIAMALLTRPEL 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQ 232
Cdd:PRK15134 178 LIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYTQ 254
|
|
| NHLM_micro_ABC1 |
TIGR03796 |
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ... |
10-226 |
5.51e-24 |
|
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 102.33 E-value: 5.51e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 10 TFG----AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIG 85
Cdd:TIGR03796 484 TFGysplEPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPREVLANSVAMVDQDIF 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 86 LFpHWTVAQNIA----TVPQ---LQKWSRSRIDDrteELMALLGldvnlrhRYPHQL-------SGGQQQRVGVARALAA 151
Cdd:TIGR03796 564 LF-EGTVRDNLTlwdpTIPDadlVRACKDAAIHD---VITSRPG-------GYDAELaegganlSGGQRQRLEIARALVR 632
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRihRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:TIGR03796 633 NPSILILDEATSALDPETEKIIDDNLRR--R--GCTCIIVAHRL-STIRDCDEIIVLERGKVVQRGTHEELWAVG 702
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
16-259 |
1.48e-23 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 100.70 E-value: 1.48e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP---VLELRRRMGYAIQS--IGLFPHW 90
Cdd:PRK10261 339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSpgkLQALRRDIQFIFQDpyASLDPRQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIAT---VPQLQKWSRSRidDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDP 167
Cdd:PRK10261 419 TVGDSIMEplrVHGLLPGKAAA--ARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDV 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 168 VTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQaffgrselgvRLLSL 247
Cdd:PRK10261 497 SIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTR----------KLMAA 566
|
250
....*....|..
gi 581977852 248 RSVGDYVRRHEQ 259
Cdd:PRK10261 567 VPVADPSRQRPQ 578
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
2-223 |
1.71e-23 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 100.48 E-value: 1.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQK-AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:PRK11176 342 IEFRNVTFTYpGKEVpALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQVAL 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHwTVAQNIATVPQlQKWSRSRIDDRTEELMAL-------LGLDVNLRHRyPHQLSGGQQQRVGVARALAAD 152
Cdd:PRK11176 422 VSQNVHLFND-TIANNIAYART-EQYSREQIEEAARMAYAMdfinkmdNGLDTVIGEN-GVLLSGGQRQRIAIARALLRD 498
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 153 PQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHdidealRL-----AEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK11176 499 SPILILDEATSALDTESERAIQAALDELQK--NRTSLVIAH------RLstiekADEILVVEDGEIVERGTHAELL 566
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-227 |
3.63e-23 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 95.72 E-value: 3.63e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRmGYA 80
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMRE-AVA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIG--LFPHWTVAQNIATVPQLQkwSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:PRK11614 84 IVPEGrrVFSRMTVEENLAMGGFFA--ERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 159 DEPFGALDPVTrgaLQQEMTRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:PRK11614 162 DEPSLGLAPII---IQQIFDTIEQLReqGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEA 229
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-224 |
6.12e-23 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 98.74 E-value: 6.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHwTVAQNIatvpQLQKwsrSRIDDrtEELMALL-------------GLDVNL----RhryphQLSGGQQQR 142
Cdd:PRK11160 419 VSQRVHLFSA-TLRDNL----LLAA---PNASD--EALIEVLqqvgleklleddkGLNAWLgeggR-----QLSGGEQRR 483
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 143 VGVARALAADPQVLLMDEPFGALDPVTRgalQQEMTRIHRL-LGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLE 221
Cdd:PRK11160 484 LGIARALLHDAPLLLLDEPTEGLDAETE---RQILELLAEHaQNKTVLMITHRL-TGLEQFDRICVMDNGQIIEQGTHQE 559
|
...
gi 581977852 222 MLT 224
Cdd:PRK11160 560 LLA 562
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
1-232 |
1.13e-22 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 94.51 E-value: 1.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGE-----EIRSLPVLELRR 75
Cdd:TIGR02323 3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRsgaelELYQLSEAERRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RM----GYAIQSI--GLFPHWTVAQNIATVP-------------QLQKW------SRSRIDDRteelmallgldvnlrhr 130
Cdd:TIGR02323 83 LMrtewGFVHQNPrdGLRMRVSAGANIGERLmaigarhygniraTAQDWleeveiDPTRIDDL----------------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 131 yPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDG 210
Cdd:TIGR02323 146 -PRAFSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQ 224
|
250 260
....*....|....*....|..
gi 581977852 211 GEVVQQGTPLEMLTAPANDFVQ 232
Cdd:TIGR02323 225 GRVVESGLTDQVLDDPQHPYTQ 246
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
15-213 |
2.51e-22 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 91.72 E-value: 2.51e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYAI---QSIGLFPHW 90
Cdd:cd03215 14 GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRAgIAYVPedrKREGLVLDL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIATvpqlqkwsrsriddrteelmallgldvnlrhryPHQLSGGQQQRVGVARALAADPQVLLMDEPfgaldpvTR 170
Cdd:cd03215 94 SVAENIAL---------------------------------SSLLSGGNQQKVVLARWLARDPRVLILDEP-------TR 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 171 G---ALQQEmtrIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:cd03215 134 GvdvGAKAE---IYRLIreladaGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
32-225 |
2.62e-22 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 93.37 E-value: 2.62e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 32 LIGTSGSGKSTTLKMINRLVEHdSGVIRFAGEEIRSLPVLELRRRMGYaiqsiglfphwtVAQNIATVPQLQKW------ 105
Cdd:COG4138 27 LIGPNGAGKSTLLARMAGLLPG-QGEILLNGRPLSDWSAAELARHRAY------------LSQQQSPPFAMPVFqylalh 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 106 -----SRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARAL-----AADP--QVLLMDEPFGALDPVTRGAL 173
Cdd:COG4138 94 qpagaSSEAVEQLLAQLAEALGLE-DKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPegQLLLLDEPMNSLDVAQQAAL 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 174 QQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTA 225
Cdd:COG4138 173 DRLLRELCQ-QGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTP 223
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
10-227 |
3.00e-22 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 94.79 E-value: 3.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 10 TFGAQK----AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD---SGVIRFAGEEIRSLPVLELRRRMGYAIQ 82
Cdd:PRK09473 21 TFSTPDgdvtAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREILNLPEKELNKLRAEQIS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 SI------GLFPHWTVAQNIATVPQLQK-WSRSridDRTEELMALLGLdVNL---RHR---YPHQLSGGQQQRVGVARAL 149
Cdd:PRK09473 101 MIfqdpmtSLNPYMRVGEQLMEVLMLHKgMSKA---EAFEESVRMLDA-VKMpeaRKRmkmYPHEFSGGMRQRVMIAMAL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 150 AADPQVLLMDEPFGALDpVTRGAlqQEMTRIHRL---LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK09473 177 LCRPKLLIADEPTTALD-VTVQA--QIMTLLNELkreFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQP 253
|
.
gi 581977852 227 A 227
Cdd:PRK09473 254 S 254
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1-229 |
4.71e-22 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 93.32 E-value: 4.71e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQ---------KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI------ 65
Cdd:PRK15112 4 LLEVRNLSKTFRYRtgwfrrqtvEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhfgdys 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 66 -RSLpvlelRRRMGYAIQSIGLFPHWTVAQnIATVP-----QLQKWSRSRiddRTEELMALLGLDVNLRHRYPHQLSGGQ 139
Cdd:PRK15112 84 yRSQ-----RIRMIFQDPSTSLNPRQRISQ-ILDFPlrlntDLEPEQREK---QIIETLRQVGLLPDHASYYPHMLAPGQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 140 QQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTP 219
Cdd:PRK15112 155 KQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGST 234
|
250
....*....|
gi 581977852 220 LEMLTAPAND 229
Cdd:PRK15112 235 ADVLASPLHE 244
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
2-217 |
7.46e-22 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 90.45 E-value: 7.46e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFG--AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGY 79
Cdd:cd03247 1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK-ALSSLISV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHwTVAQNIATvpqlqkwsrsriddrteelmallgldvnlrhryphQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:cd03247 80 LNQRPYLFDT-TLRNNLGR-----------------------------------RFSGGERQRLALARILLQDAPIVLLD 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 160 EPFGALDPVTRGALQQEMTRIhrLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03247 124 EPTVGLDPITERQLLSLIFEV--LKDKTLIWITHHL-TGIEHMDKILFLENGKIIMQG 178
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
2-217 |
7.77e-22 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 91.44 E-value: 7.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF----------------------GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIR 59
Cdd:cd03220 1 IELENVSKSYptykggssslkklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 60 FAGeeiRSLPVLELrrrmgyaiqSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMAL--LGLDVNLRHRyphQLSG 137
Cdd:cd03220 81 VRG---RVSSLLGL---------GGGFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFseLGDFIDLPVK---TYSS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 138 GQQQRVGVARALAADPQVLLMDEPFGALDPvtrgALQQEMT-RIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:cd03220 146 GMKARLAFAIATALEPDILLIDEVLAVGDA----AFQEKCQrRLRELLkqGKTVILVSHDPSSIKRLCDRALVLEKGKIR 221
|
...
gi 581977852 215 QQG 217
Cdd:cd03220 222 FDG 224
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-210 |
1.03e-21 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 95.00 E-value: 1.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDS--GVIRFAGEEIRSLPVLELRRRmG 78
Cdd:PRK13549 5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTyeGEIIFEGEELQASNIRDTERA-G 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAI--QSIGLFPHWTVAQNIAtvpqL-QKWSRS-RIDD-----RTEELMALLGLDVNLRHRYPHqLSGGQQQRVGVARAL 149
Cdd:PRK13549 84 IAIihQELALVKELSVLENIF----LgNEITPGgIMDYdamylRAQKLLAQLKLDINPATPVGN-LGLGQQQLVEIAKAL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 150 AADPQVLLMDEPFGALdpvTRGALQQEMTRIHRLLGRTI--VLVTHDIDEALRLAEHL-VLMDG 210
Cdd:PRK13549 159 NKQARLLILDEPTASL---TESETAVLLDIIRDLKAHGIacIYISHKLNEVKAISDTIcVIRDG 219
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
15-233 |
1.23e-21 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 93.11 E-value: 1.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLP--VLELRRRmgyAIQSI------GL 86
Cdd:PRK11308 29 KALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADpeAQKLLRQ---KIQIVfqnpygSL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 87 FPHWTVAQnIATVPQL--QKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGA 164
Cdd:PRK11308 106 NPRKKVGQ-ILEEPLLinTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSA 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 165 LDPVTRGA-------LQQEMtrihrllGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQA 233
Cdd:PRK11308 185 LDVSVQAQvlnlmmdLQQEL-------GLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPRHPYTQA 253
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
2-226 |
1.27e-21 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 95.17 E-value: 1.27e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAV---NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:TIGR00958 479 IEFQDVSFSYPNRPDVpvlKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVA 558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHwTVAQNIA------TVPQLQKWSR-SRIDDRTEELMAllGLDVNLRHRyPHQLSGGQQQRVGVARALAA 151
Cdd:TIGR00958 559 LVGQEPVLFSG-SVRENIAygltdtPDEEIMAAAKaANAHDFIMEFPN--GYDTEVGEK-GSQLSGGQKQRIAIARALVR 634
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRihrlLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:TIGR00958 635 KPRVLILDEATSALDAECEQLLQESRSR----ASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQ 704
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
12-238 |
2.54e-21 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 92.17 E-value: 2.54e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMI------NRLVEHDSgvIRFAGEEIRSLPVLELRRRMGYAIQSI- 84
Cdd:PRK15093 18 GWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAIcgvtkdNWRVTADR--MRFDDIDLLRLSPRERRKLVGHNVSMIf 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 -----GLFPHWTVA-QNIATVP---------QLQKWsRSRiddRTEELMALLGLD--VNLRHRYPHQLSGGQQQRVGVAR 147
Cdd:PRK15093 96 qepqsCLDPSERVGrQLMQNIPgwtykgrwwQRFGW-RKR---RAIELLHRVGIKdhKDAMRSFPYELTEGECQKVMIAI 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPA 227
Cdd:PRK15093 172 ALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTPH 251
|
250
....*....|....*..
gi 581977852 228 NDFVQAF------FGRS 238
Cdd:PRK15093 252 HPYTQALiraipdFGSA 268
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
17-214 |
2.64e-21 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 93.93 E-value: 2.64e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNL--HFREGSFSV-------LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEE--IRSlPVLELRRRMGYAI---Q 82
Cdd:COG1129 259 VEGLSVggVVRDVSFSVrageilgIAGLVGAGRTELARALFGADPADSGEIRLDGKPvrIRS-PRDAIRAGIAYVPedrK 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 SIGLFPHWTVAQNIaTVPQLQKWSR------SRIDDRTEELMALLgldvNLRHRYPHQ----LSGGQQQRVGVARALAAD 152
Cdd:COG1129 338 GEGLVLDLSIRENI-TLASLDRLSRgglldrRRERALAEEYIKRL----RIKTPSPEQpvgnLSGGNQQKVVLAKWLATD 412
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 153 PQVLLMDEPfgaldpvTRG----ALQQemtrIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:COG1129 413 PKVLILDEP-------TRGidvgAKAE----IYRLIrelaaeGKAVIVISSELPELLGLSDRILVMREGRIV 473
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-214 |
4.06e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 93.21 E-value: 4.06e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFaGEEIRslpvlelrrrMGY- 79
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVK----------IGYf 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIatvpqlqkwSRSRIDDRTEELMALLGL------DVnlrHRYPHQLSGGQQQRVGVARALAADP 153
Cdd:COG0488 384 DQHQEELDPDKTVLDEL---------RDGAPGGTEQEVRGYLGRflfsgdDA---FKPVGVLSGGEKARLALAKLLLSPP 451
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 154 QVLLMDEPFGALDPVTRGALQQemtrihrLLGR---TIVLVTHD---IDealRLAEHLVLMDGGEVV 214
Cdd:COG0488 452 NVLLLDEPTNHLDIETLEALEE-------ALDDfpgTVLLVSHDryfLD---RVATRILEFEDGGVR 508
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
2-217 |
5.08e-21 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 89.70 E-value: 5.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF----------GAQK-----------AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRF 60
Cdd:cd03267 1 IEVSNLSKSYrvyskepgliGSLKslfkrkyreveALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 61 AGE---EIRSlpvlELRRRMGYAI-QSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLG----LDVNLRhryp 132
Cdd:cd03267 81 AGLvpwKRRK----KFLRRIGVVFgQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDleelLDTPVR---- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 133 hQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGE 212
Cdd:cd03267 153 -QLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGR 231
|
....*
gi 581977852 213 VVQQG 217
Cdd:cd03267 232 LLYDG 236
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
16-282 |
6.38e-21 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 93.00 E-value: 6.38e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI--RSLPVLELRRRMGYAIQSI--------- 84
Cdd:PRK10261 31 AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLrrRSRQVIELSEQSAAQMRHVrgadmamif 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 -----GLFPHWTVAQNIATVPQL-QKWSRS-------RIDD--RTEELMALLGldvnlrhRYPHQLSGGQQQRVGVARAL 149
Cdd:PRK10261 111 qepmtSLNPVFTVGEQIAESIRLhQGASREeamveakRMLDqvRIPEAQTILS-------RYPHQLSGGMRQRVMIAMAL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 150 AADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAND 229
Cdd:PRK10261 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHP 263
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 230 FVQAFFGR-SELGV-------RLLSLRSVGDYVRRHEQVGGDALAEE---MTLRDALSVFVARG 282
Cdd:PRK10261 264 YTRALLAAvPQLGAmkgldypRRFPLISLEHPAKQEPPIEQDTVVDGepiLQVRNLVTRFPLRS 327
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-213 |
6.71e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 92.82 E-value: 6.71e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 4 FSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEirslpvlelrrRMGYAIQS 83
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL-----------RIGYLPQE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHWTVAQNIATV----------------------PQLQKWSR--SRIDD--------RTEELMALLGLDVNLRHRY 131
Cdd:COG0488 70 PPLDDDLTVLDTVLDGdaelraleaeleeleaklaepdEDLERLAElqEEFEAlggweaeaRAEEILSGLGFPEEDLDRP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 132 PHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEmtrihrLLGR--TIVLVTHD---IDealRLAEHLV 206
Cdd:COG0488 150 VSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEF------LKNYpgTVLVVSHDryfLD---RVATRIL 220
|
....*..
gi 581977852 207 LMDGGEV 213
Cdd:COG0488 221 ELDRGKL 227
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
2-194 |
7.47e-21 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 92.81 E-value: 7.47e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:TIGR02868 335 LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVC 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFpHWTVAQNIATvpqlqkwsrSRIDDRTEELMALL---GLDVNLRhRYPH-----------QLSGGQQQRVGVA 146
Cdd:TIGR02868 415 AQDAHLF-DTTVRENLRL---------ARPDATDEELWAALervGLADWLR-ALPDgldtvlgeggaRLSGGERQRLALA 483
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 581977852 147 RALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHD 194
Cdd:TIGR02868 484 RALLADAPILLLDEPTEHLDAETADELLEDLLAALS--GRTVVLITHH 529
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-253 |
1.04e-20 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 92.17 E-value: 1.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRL--VEHDSGVIRF------------------- 60
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYhvalcekcgyverpskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 61 ----AGEEIRSLPV----------LELRRRMGYAIQ-SIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALlgldV 125
Cdd:TIGR03269 81 pcpvCGGTLEPEEVdfwnlsdklrRRIRKRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEM----V 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 126 NLRHRYPH---QLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLA 202
Cdd:TIGR03269 157 QLSHRITHiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLS 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 203 EHLVLMDGGEVVQQGTPLEMLtapaNDFVQAF-----FGRSELGVRLLSLRSVGDY 253
Cdd:TIGR03269 237 DKAIWLENGEIKEEGTPDEVV----AVFMEGVsevekECEVEVGEPIIKVRNVSKR 288
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
2-223 |
2.67e-20 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 91.03 E-value: 2.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSktFG---AQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:COG5265 358 VRFENVS--FGydpERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIG 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHwTVAQNIATvpqlqkwsrSRIDDRTEELMA------LLGLDVNLRHRYPHQ-------LSGGQQQRVGV 145
Cdd:COG5265 436 IVPQDTVLFND-TIAYNIAY---------GRPDASEEEVEAaaraaqIHDFIESLPDGYDTRvgerglkLSGGEKQRVAI 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 146 ARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHdidealRL-----AEHLVLMDGGEVVQQGTPL 220
Cdd:COG5265 506 ARTLLKNPPILIFDEATSALDSRTERAIQAALREVAR--GRTTLVIAH------RLstivdADEILVLEAGRIVERGTHA 577
|
...
gi 581977852 221 EML 223
Cdd:COG5265 578 ELL 580
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
32-226 |
2.72e-20 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 88.07 E-value: 2.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 32 LIGTSGSGKSTTLKMINRLVEHdSGVIRFAGEEIRSLPVLELRRRMGYAIQSiglfphwtvaQNIAT-VPQLQKWSRSR- 109
Cdd:PRK03695 27 LVGPNGAGKSTLLARMAGLLPG-SGSIQFAGQPLEAWSAAELARHRAYLSQQ----------QTPPFaMPVFQYLTLHQp 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 110 -------IDDRTEELMALLGLDVNLrHRYPHQLSGGQQQRVGVA-------RALAADPQVLLMDEPFGALDPVTRGALQQ 175
Cdd:PRK03695 96 dktrteaVASALNEVAEALGLDDKL-GRSVNQLSGGEWQRVRLAavvlqvwPDINPAGQLLLLDEPMNSLDVAQQAALDR 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 176 EMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK03695 175 LLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPE 224
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
20-218 |
3.16e-20 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 91.06 E-value: 3.16e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 20 LNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHdSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFpHWTVAQNI--- 96
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPY-QGSLKINGIELRELDPESWRKHLSWVGQNPQLP-HGTLRDNVllg 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 97 ---ATVPQLQK-WSRSRIDDRTEELMalLGLDvnlrhrYPHQ-----LSGGQQQRVGVARALAADPQVLLMDEPFGALDP 167
Cdd:PRK11174 447 npdASDEQLQQaLENAWVSEFLPLLP--QGLD------TPIGdqaagLSVGQAQRLALARALLQPCQLLLLDEPTASLDA 518
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 168 VTRGALQQEMTRIHRllGRTIVLVTHDIDEaLRLAEHLVLMDGGEVVQQGT 218
Cdd:PRK11174 519 HSEQLVMQALNAASR--RQTTLMVTHQLED-LAQWDQIWVMQDGQIVQQGD 566
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-219 |
7.28e-20 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 86.01 E-value: 7.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTF--GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGY 79
Cdd:cd03244 3 IEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHwTVAQNIAtvPqLQKWS---------RSRIDDRTEELMALLGLDVNLRhryPHQLSGGQQQRVGVARALA 150
Cdd:cd03244 83 IPQDPVLFSG-TIRSNLD--P-FGEYSdeelwqaleRVGLKEFVESLPGGLDTVVEEG---GENLSVGQRQLLCLARALL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 151 ADPQVLLMDEPFGALDPVTRgALQQEMTRiHRLLGRTIVLVTHDIDEALRLAEHLVlMDGGEVVQQGTP 219
Cdd:cd03244 156 RKSKILVLDEATASVDPETD-ALIQKTIR-EAFKDCTVLTIAHRLDTIIDSDRILV-LDKGRVVEFDSP 221
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
7-217 |
7.37e-20 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 86.90 E-value: 7.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLEL---RRRM------ 77
Cdd:PRK11701 12 LTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALseaERRRllrtew 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSI--GLFPHWTVAQNIATVPQLQKWSR-SRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:PRK11701 92 GFVHQHPrdGLRMQVSAGGNIGERLMAVGARHyGDIRATAGDWLERVEIDAARIDDLPTTFSGGMQQRLQIARNLVTHPR 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 155 VLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:PRK11701 172 LVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESG 234
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1-238 |
1.54e-19 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 86.20 E-value: 1.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRrMGY- 79
Cdd:PRK11300 5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIAR-MGVv 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 -AIQSIGLFPHWTVAQN--IATVPQLQK-----------WSRSRID--DRTEELMALLGLdVNLRHRYPHQLSGGQQQRV 143
Cdd:PRK11300 84 rTFQHVRLFREMTVIENllVAQHQQLKTglfsgllktpaFRRAESEalDRAATWLERVGL-LEHANRQAGNLAYGQQRRL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 144 GVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK11300 163 EIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIR 242
|
250
....*....|....*
gi 581977852 224 TAPanDFVQAFFGRS 238
Cdd:PRK11300 243 NNP--DVIKAYLGEA 255
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-237 |
2.22e-19 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 88.34 E-value: 2.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDS--GVIRFAGEEIRSLPVLELRRRmG 78
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASNIRDTERA-G 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAI--QSIGLFPHWTVAQNIATVPQLQKwSRSRIDD-----RTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAA 151
Cdd:TIGR02633 80 IVIihQELTLVPELSVAENIFLGNEITL-PGGRMAYnamylRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 152 DPQVLLMDEPFGALdpvTRGALQQEMTRIHRLLGRTI--VLVTHDIDEALRLAEHLVLMDGGEVVQQgTPLEMLTAPanD 229
Cdd:TIGR02633 159 QARLLILDEPSSSL---TEKETEILLDIIRDLKAHGVacVYISHKLNEVKAVCDTICVIRDGQHVAT-KDMSTMSED--D 232
|
....*...
gi 581977852 230 FVQAFFGR 237
Cdd:TIGR02633 233 IITMMVGR 240
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-219 |
2.98e-19 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 88.26 E-value: 2.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGS-FSVLiGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvLELRRRMGYA 80
Cdd:NF033858 267 IEARGLTMRFGDFTAVDHVSFRIRRGEiFGFL-GSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGD-IATRRRVGYM 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:NF033858 345 SQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 161 PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTP 219
Cdd:NF033858 424 PTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTP 481
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
16-214 |
5.80e-19 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 87.00 E-value: 5.80e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR-MGYaI----QSIGLFPHW 90
Cdd:COG3845 273 ALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERRRLgVAY-IpedrLGRGLVPDM 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIA----TVPQLQKW---SRSRIDDRTEELMAllGLDVnlRHRYPHQ----LSGGQQQRVGVARALAADPQVLLMD 159
Cdd:COG3845 352 SVAENLIlgryRRPPFSRGgflDRKAIRAFAEELIE--EFDV--RTPGPDTparsLSGGNQQKVILARELSRDPKLLIAA 427
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 160 EPFGALDPvtrGALQQemtrIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:COG3845 428 QPTRGLDV---GAIEF----IHQRLlelrdaGAAVLLISEDLDEILALSDRIAVMYEGRIV 481
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-214 |
6.77e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 85.52 E-value: 6.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF----------GAQK-----------AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIR 59
Cdd:COG4586 1 IIEVENLSKTYrvyekepglkGALKglfrreyreveAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 60 FAGEEirslPVlelRRRMGYAiQSIG--------LFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRY 131
Cdd:COG4586 81 VLGYV----PF---KRRKEFA-RRIGvvfgqrsqLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLG-ELLDTP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 132 PHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGG 211
Cdd:COG4586 152 VRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHG 231
|
...
gi 581977852 212 EVV 214
Cdd:COG4586 232 RII 234
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-216 |
7.13e-19 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 84.01 E-value: 7.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeirslpvlelRRRMGYA 80
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNG-----------KLRIGYV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPhwtvaqniaTVP-QLQKWSRSRIDDRTEELM-ALLGLDVNLRHRYPHQ-LSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK09544 73 PQKLYLDT---------TLPlTVNRFLRLRPGTKKEDILpALKRVQAGHLIDAPMQkLSGGETQRVLLARALLNRPQLLV 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 158 MDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDI-------DEALRLAEHLVLMDGGEVVQQ 216
Cdd:PRK09544 144 LDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLhlvmaktDEVLCLNHHICCSGTPEVVSL 209
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
16-226 |
7.39e-19 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 86.69 E-value: 7.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwTVAQN 95
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSD-TVANN 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 96 IA----TVPQLQKWSRSRIDDRTEELMAL-LGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTR 170
Cdd:PRK10789 409 IAlgrpDATQQEIEHVARLASVHDDILRLpQGYDTEVGER-GVMLSGGQKQRISIARALLLNAEILILDDALSAVDGRTE 487
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 171 GALQQEMTRIHRllGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PRK10789 488 HQILHNLRQWGE--GRTVIISAHRL-SALTEASEILVMQHGHIAQRGNHDQLAQQS 540
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-256 |
1.95e-18 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 85.61 E-value: 1.95e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSL-PVLELRRRMGY 79
Cdd:PRK09700 5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLdHKLAAQLGIGI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSIGLFPHWTVAQNIATVPQLQK---------WSRSRIddRTEELMALLGLDVNLRHRYPhQLSGGQQQRVGVARALA 150
Cdd:PRK09700 85 IYQELSVIDELTVLENLYIGRHLTKkvcgvniidWREMRV--RAAMMLLRVGLKVDLDEKVA-NLSISHKQMLEIAKTLM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 151 ADPQVLLMDEPFGALdpvTRGALQQEMTRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGtpleMLTAPAN 228
Cdd:PRK09700 162 LDAKVIIMDEPTSSL---TNKEVDYLFLIMNQLRkeGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG----MVSDVSN 234
|
250 260
....*....|....*....|....*....
gi 581977852 229 -DFVQAFFGRsELGVRLLSLRSVGDYVRR 256
Cdd:PRK09700 235 dDIVRLMVGR-ELQNRFNAMKENVSNLAH 262
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
17-193 |
3.77e-18 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 84.86 E-value: 3.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSfSVLI-GTSGSGKSTTLKMINRLVEHDSGVIRF-AGEEI-----RS-LPVLELRRrmgyAIqsigLFP 88
Cdd:COG4178 379 LEDLSLSLKPGE-RLLItGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVlflpqRPyLPLGTLRE----AL----LYP 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 89 HwtvaqniatvpqlqkwSRSRIDDrtEELMALLGlDVNLRH---------RYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:COG4178 450 A----------------TAEAFSD--AELREALE-AVGLGHlaerldeeaDWDQVLSLGEQQRLAFARLLLHKPDWLFLD 510
|
170 180 190
....*....|....*....|....*....|....
gi 581977852 160 EPFGALDPVTRGALQQEMtrIHRLLGRTIVLVTH 193
Cdd:COG4178 511 EATSALDEENEAALYQLL--REELPGTTVISVGH 542
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
12-193 |
4.29e-18 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 80.87 E-value: 4.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 12 GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAIQSIGLFPHWT 91
Cdd:TIGR01189 11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRD-EPHENILYLGHLPGLKPELS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 92 VAQNiatvpqLQKWSR-SRIDDRT-EELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVT 169
Cdd:TIGR01189 90 ALEN------LHFWAAiHGGAQRTiEDALAAVGLT-GFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAG 162
|
170 180
....*....|....*....|....
gi 581977852 170 RGALQQEMtRIHRLLGRTIVLVTH 193
Cdd:TIGR01189 163 VALLAGLL-RAHLARGGIVLLTTH 185
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
19-193 |
6.85e-18 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 80.30 E-value: 6.85e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLElrrRMGYAIQSIGLFPHWTVAQNiat 98
Cdd:PRK13539 20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAE---ACHYLGHRNAMKPALTVAEN--- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 vpqLQKWSRSRIDDRT--EELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRgALQQE 176
Cdd:PRK13539 94 ---LEFWAAFLGGEELdiAAALEAVGLA-PLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAV-ALFAE 168
|
170
....*....|....*..
gi 581977852 177 MTRIHRLLGRTIVLVTH 193
Cdd:PRK13539 169 LIRAHLAQGGIVIAATH 185
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
15-224 |
8.70e-18 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 83.68 E-value: 8.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR-SLPVLELRRRMGYAIQS---IGLFPHW 90
Cdd:PRK09700 277 KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISpRSPLDAVKKGMAYITESrrdNGFFPNF 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIATVPQLQ----KWSRSRIDDRTEELMA-----LLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:PRK09700 357 SIAQNMAISRSLKdggyKGAMGLFHEVDEQRTAenqreLLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 162 fgaldpvTRG---ALQQEMTRIHRLL---GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:PRK09700 437 -------TRGidvGAKAEIYKVMRQLaddGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMS 498
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-194 |
8.79e-18 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 78.26 E-value: 8.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRfageeirslpvlelrrrmgyai 81
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVT---------------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 qsiglfphwtvaqniatvpqlqkwsrsriddrteelmallgLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03221 59 -----------------------------------------WGSTVKIGYFEQLSGGEKMRLALAKLLLENPNLLLLDEP 97
|
170 180 190
....*....|....*....|....*....|...
gi 581977852 162 FGALDPVTRGALQQEMTRIHrllgRTIVLVTHD 194
Cdd:cd03221 98 TNHLDLESIEALEEALKEYP----GTVILVSHD 126
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
3-271 |
1.82e-17 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 82.65 E-value: 1.82e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 3 EFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR---SLPVLElrrrMGY 79
Cdd:PRK11288 6 SFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRfasTTAALA----AGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AI--QSIGLFPHWTVAQNI--ATVPQLQKW-SRSRIDDRTEELMALLGLDVN----LRHryphqLSGGQQQRVGVARALA 150
Cdd:PRK11288 82 AIiyQELHLVPEMTVAENLylGQLPHKGGIvNRRLLNYEAREQLEHLGVDIDpdtpLKY-----LSIGQRQMVEIAKALA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 151 ADPQVLLMDEPFGALDpvtrgalQQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHL-VLMDGGEVvqqGTPLEML 223
Cdd:PRK11288 157 RNARVIAFDEPTSSLS-------AREIEQLFRVIrelraeGRVILYVSHRMEEIFALCDAItVFKDGRYV---ATFDDMA 226
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 581977852 224 TAPANDFVQAFFGRSELGVRLLSLRSVGDYVRRHEQVGGDALAEEMTL 271
Cdd:PRK11288 227 QVDRDQLVQAMVGREIGDIYGYRPRPLGEVRLRLDGLKGPGLREPISF 274
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-233 |
4.04e-17 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 81.64 E-value: 4.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSL-PVLElrRRMG- 78
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLtPAKA--HQLGi 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAI-QSIGLFPHWTVAQNIA-TVPQLQKWSRsriddRTEELMALLGLDVNLrHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:PRK15439 89 YLVpQEPLLFPNLSVKENILfGLPKRQASMQ-----KMKQLLAALGCQLDL-DSSAGSLEVADRQIVEILRGLMRDSRIL 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 157 LMDEPFGALDPVTRGALqqeMTRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGtplEMLTAPANDFVQA 233
Cdd:PRK15439 163 ILDEPTASLTPAETERL---FSRIRELLaqGVGIVFISHKLPEIRQLADRISVMRDGTIALSG---KTADLSTDDIIQA 235
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
2-213 |
4.11e-17 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 78.67 E-value: 4.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVN---DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:cd03248 12 VKFQNVTFAYPTRPDTLvlqDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHwTVAQNIA----TVPQ---LQKWSRSRIDDRTEELMALLGLDVNLRHrypHQLSGGQQQRVGVARALAA 151
Cdd:cd03248 92 LVGQEPVLFAR-SLQDNIAyglqSCSFecvKEAAQKAHAHSFISELASGYDTEVGEKG---SQLSGGQKQRVAIARALIR 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 152 DPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHDIDEALRlAEHLVLMDGGEV 213
Cdd:cd03248 168 NPQVLILDEATSALDAESEQQVQQALYDWPE--RRTVLVIAHRLSTVER-ADQILVLDGGRI 226
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
20-223 |
6.25e-17 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 79.28 E-value: 6.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 20 LNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEI----RSLpvLELRRRMGYAIQSIGLFPHWT-VAQ 94
Cdd:PRK13638 20 LNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdyskRGL--LALRQQVATVFQDPEQQIFYTdIDS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 95 NIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGalq 174
Cdd:PRK13638 98 DIAFSLRNLGVPEAEITRRVDEALTLVDAQ-HFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRT--- 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 175 QEMTRIHRLL--GRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK13638 174 QMIAIIRRIVaqGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
17-233 |
1.01e-16 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 78.20 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTT----LKMINRLVEHDSGVIRFAGEEIRSLpvlELRRRMgyaIQSIGLFPH--W 90
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSLTcaaaLGILPAGVRQTAGRVLLDGKPVAPC---ALRGRK---IATIMQNPRsaF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 91 TVAQNIAT--VPQLQKWSRSRIDDRTEELMALLGLDVNLR--HRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALD 166
Cdd:PRK10418 93 NPLHTMHThaRETCLALGKPADDATLTAALEAVGLENAARvlKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLD 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 167 PVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLTAPANDFVQA 233
Cdd:PRK10418 173 VVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRS 239
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
7-199 |
3.54e-16 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 76.15 E-value: 3.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGA------QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVE--HDSGVIRFAGEEI-RSLPVLElrrrm 77
Cdd:COG2401 30 VLEAFGVelrvveRYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPDNQFgREASLID----- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 gyaiqsiGLFPHWTVAQNIatvpqlqkwsrsriddrteELMALLGL-DVNLRHRYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:COG2401 105 -------AIGRKGDFKDAV-------------------ELLNAVGLsDAVLWLRRFKELSTGQKFRFRLALLLAERPKLL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 581977852 157 LMDEpFGA-LDPVTRGALQQEMTRIHRLLGRTIVLVTH--DIDEAL 199
Cdd:COG2401 159 VIDE-FCShLDRQTAKRVARNLQKLARRAGITLVVATHhyDVIDDL 203
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
28-219 |
4.71e-16 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 75.53 E-value: 4.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 28 SFSV-------LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwTVAQNIATVp 100
Cdd:cd03369 28 SFKVkagekigIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIPQDPTLFSG-TIRSNLDPF- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 101 qlqkwsrSRIDDrtEELMALL-----GLDvnlrhryphqLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQ 175
Cdd:cd03369 106 -------DEYSD--EEIYGALrvsegGLN----------LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQK 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 581977852 176 EmtrIHRLL-GRTIVLVTHDIDEALRLAEHLVlMDGGEVVQQGTP 219
Cdd:cd03369 167 T---IREEFtNSTILTIAHRLRTIIDYDKILV-MDAGEVKEYDHP 207
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
16-236 |
1.06e-15 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 75.69 E-value: 1.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlpvlELRRRM-GYAIQSIGLfpHWTVAQ 94
Cdd:PRK15056 22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ----ALQKNLvAYVPQSEEV--DWSFPV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 95 NIATVPQLQKWS------RSRIDDRTEELMALLGLD-VNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDP 167
Cdd:PRK15056 96 LVEDVVMMGRYGhmgwlrRAKKRDRQIVTAALARVDmVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDV 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 168 VTRGALqQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGgeVVQQGTPLEMlTAPANDFVQAFFG 236
Cdd:PRK15056 176 KTEARI-ISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVKG--TVLASGPTET-TFTAENLELAFSG 240
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1-210 |
7.37e-15 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 74.83 E-value: 7.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDS--GVIRFAGEE-----IRSlpvlel 73
Cdd:NF040905 1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGEVcrfkdIRD------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 74 RRRMGYAI--QSIGLFPHWTVAQNIATVPQLQK-----WSRSRIddRTEELMALLGLDVNlrhryPHQLSG----GQQQR 142
Cdd:NF040905 75 SEALGIVIihQELALIPYLSIAENIFLGNERAKrgvidWNETNR--RARELLAKVGLDES-----PDTLVTdigvGKQQL 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 143 VGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIhRLLGRTIVLVTHDIDEALRLAEHL-VLMDG 210
Cdd:NF040905 148 VEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSItVLRDG 215
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
5-224 |
1.28e-14 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 74.00 E-value: 1.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 5 SHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR---SLPVLELRRRMGYai 81
Cdd:PRK10982 2 SNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDfksSKEALENGISMVH-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFPHWTVAQNIatvpQLQKWSR-------SRIDDRTEELMALLGLDVNLRHRYPhQLSGGQQQRVGVARALAADPQ 154
Cdd:PRK10982 80 QELNLVLQRSVMDNM----WLGRYPTkgmfvdqDKMYRDTKAIFDELDIDIDPRAKVA-TLSVSQMQMIEIAKAFSYNAK 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 155 VLLMDEPFGALdpvTRGALQQEMTRIHRLLGR--TIVLVTHDIDEALRLAEHL-VLMDGGEVVQQgtPLEMLT 224
Cdd:PRK10982 155 IVIMDEPTSSL---TEKEVNHLFTIIRKLKERgcGIVYISHKMEEIFQLCDEItILRDGQWIATQ--PLAGLT 222
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
16-218 |
1.68e-14 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 74.28 E-value: 1.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 16 AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlPVLELRRRMGYAIQSIGLFPHWTVAQN 95
Cdd:TIGR01257 1954 AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT-NISDVHQNMGYCPQFDAIDDLLTGREH 2032
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 96 IATVPQLQKWSRSRIDDRTEELMALLGLDVnLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQ 175
Cdd:TIGR01257 2033 LYLYARLRGVPAEEIEKVANWSIQSLGLSL-YADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWN 2111
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 581977852 176 EMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGT 218
Cdd:TIGR01257 2112 TIVSIIR-EGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1-234 |
4.47e-14 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 73.02 E-value: 4.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF--GAQKAVNDLNLHFREG--------SFSV-------LIGTSGSGKSTTLKMINRLVEHDsGVIRFAGE 63
Cdd:TIGR01271 1202 VIENPHAQKCWpsGGQMDVQGLTAKYTEAgravlqdlSFSVeggqrvgLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGV 1280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 64 EIRSLPVLELRRRMGYAIQSIGLFPHwTVAQNIATVPQlqkWSRSRIDDRTEELmallGLDvNLRHRYPHQL-------- 135
Cdd:TIGR01271 1281 SWNSVTLQTWRKAFGVIPQKVFIFSG-TFRKNLDPYEQ---WSDEEIWKVAEEV----GLK-SVIEQFPDKLdfvlvdgg 1351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 136 ---SGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQemTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMdgGE 212
Cdd:TIGR01271 1352 yvlSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRK--TLKQSFSNCTVILSEHRVEALLECQQFLVIE--GS 1427
|
250 260
....*....|....*....|..
gi 581977852 213 VVQQGTPLEMLTAPANDFVQAF 234
Cdd:TIGR01271 1428 SVKQYDSIQKLLNETSLFKQAM 1449
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-234 |
4.81e-14 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 72.85 E-value: 4.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMInrlvehdSGVIRFAGEEIRslpVL---------- 71
Cdd:NF033858 2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLI-------AGARKIQQGRVE---VLggdmadarhr 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 72 -ELRRRMGYAIQSIG--LFPHWTVAQNIATVPQL----QKWSRSRIDdrteELMALLGLDvNLRHRYPHQLSGGQQQRVG 144
Cdd:NF033858 72 rAVCPRIAYMPQGLGknLYPTLSVFENLDFFGRLfgqdAAERRRRID----ELLRATGLA-PFADRPAGKLSGGMKQKLG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 145 VARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLV-THDIDEALRLaEHLVLMDGGEVVQQGTPLEML 223
Cdd:NF033858 147 LCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERPGMSVLVaTAYMEEAERF-DWLVAMDAGRVLATGTPAELL 225
|
250
....*....|..
gi 581977852 224 T-APANDFVQAF 234
Cdd:NF033858 226 ArTGADTLEAAF 237
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-210 |
7.38e-14 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 71.57 E-value: 7.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIR-SLPvlELRRRMGY 79
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfNGP--KSSQEAGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AI--QSIGLFPHWTVAQNIATVPQL-QKWSR---SRIDDRTEELMALLgldvNLRHRyPHQLSG----GQQQRVGVARAL 149
Cdd:PRK10762 82 GIihQELNLIPQLTIAENIFLGREFvNRFGRidwKKMYAEADKLLARL----NLRFS-SDKLVGelsiGEQQMVEIAKVL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 150 AADPQVLLMDEPFGALDPVTRGALqqeMTRIHRLL--GRTIVLVTHDIDEALRLAEHL-VLMDG 210
Cdd:PRK10762 157 SFESKVIIMDEPTDALTDTETESL---FRVIRELKsqGRGIVYISHRLKEIFEICDDVtVFRDG 217
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-224 |
7.50e-14 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 70.24 E-value: 7.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMI-NRLVEHD-------SGVIRFAGEEIRSLPVLE 72
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALaGDLTGGGaprgarvTGDVTLNGEPLAAIDAPR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRM---------GYA-----IQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTeelmALLGLDVNlrhryphQLSGG 138
Cdd:PRK13547 81 LARLRavlpqaaqpAFAfsareIVLLGRYPHARRAGALTHRDGEIAWQALALAGAT----ALVGRDVT-------TLSGG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 139 QQQRVGVARALA---------ADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMD 209
Cdd:PRK13547 150 ELARVQFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLA 229
|
250
....*....|....*
gi 581977852 210 GGEVVQQGTPLEMLT 224
Cdd:PRK13547 230 DGAIVAHGAPADVLT 244
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
4-193 |
1.25e-13 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 68.29 E-value: 1.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 4 FSHVSKTFGAQKAVndlnlhfregsfsVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAIQS 83
Cdd:cd03231 16 FSGLSFTLAAGEAL-------------QVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRD-SIARGLLYLGHA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHWTVAQNiatvpqLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFG 163
Cdd:cd03231 82 PGIKTTLSVLEN------LRFWHADHSDEQVEEALARVGLN-GFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTT 154
|
170 180 190
....*....|....*....|....*....|
gi 581977852 164 ALDPVTRGALQQEMtRIHRLLGRTIVLVTH 193
Cdd:cd03231 155 ALDKAGVARFAEAM-AGHCARGGMVVLTTH 183
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-225 |
3.17e-13 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 70.13 E-value: 3.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAV-NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVlQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAMV 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQ-----SIGLFPHWTVAQNIA---------TVpQLQKWSRSRiddrTEELMALLGLDVNlrhryphQLSGGQQQRVGVA 146
Cdd:PRK10790 421 QQdpvvlADTFLANVTLGRDISeeqvwqaleTV-QLAELARSL----PDGLYTPLGEQGN-------NLSVGQKQLLALA 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 147 RALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRllGRTIVLVTHdidealRL-----AEHLVLMDGGEVVQQGTPLE 221
Cdd:PRK10790 489 RVLVQTPQILILDEATANIDSGTEQAIQQALAAVRE--HTTLVVIAH------RLstiveADTILVLHRGQAVEQGTHQQ 560
|
....
gi 581977852 222 MLTA 225
Cdd:PRK10790 561 LLAA 564
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
18-219 |
4.80e-13 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 67.40 E-value: 4.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 18 NDLNLHFREGSFSVLIGTSGSGKSTTLKMI--NRLVEHDSGVIRFAGEEIRSLPVLElRRRMG--YAIQSIGLFPHWTVA 93
Cdd:COG0396 17 KGVNLTIKPGEVHAIMGPNGSGKSTLAKVLmgHPKYEVTSGSILLDGEDILELSPDE-RARAGifLAFQYPVEIPGVSVS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 94 QNIATVpqLQKWSRSRIDDRT-----EELMALLGLDVNLRHRYPHQ-LSGGQQQRVGVARALAADPQVLLMDEP-FG--- 163
Cdd:COG0396 96 NFLRTA--LNARRGEELSAREflkllKEKMKELGLDEDFLDRYVNEgFSGGEKKRNEILQMLLLEPKLAILDETdSGldi 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 164 -ALDPVTRG--ALQQEmtrihrllGRTIVLVTHdideALRLAEHL------VLMDgGEVVQQGTP 219
Cdd:COG0396 174 dALRIVAEGvnKLRSP--------DRGILIITH----YQRILDYIkpdfvhVLVD-GRIVKSGGK 225
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
2-224 |
4.94e-13 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 68.61 E-value: 4.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTtlkmiNRLVEHDSGVIrfAGEEIRSLPVL-----ELRRR 76
Cdd:NF000106 14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**R-----GALPAHV*GPD--AGRRPWRF*TWcanrrALRRT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MG-YAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLdVNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:NF000106 87 IG*HRPVR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSL-TEAAGRAAAKYSGGMRRRLDLAASMIGRPAV 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQGTPLEMLT 224
Cdd:NF000106 166 LYLDEPTTGLDPRTRNEVWDEVRSMVR-DGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKT 233
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
2-193 |
5.80e-13 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 65.64 E-value: 5.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVS-KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSG-VIRFAGEEIRSLPvlelrrRMGY 79
Cdd:cd03223 1 IELENLSlATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGrIGMPEGEDLLFLP------QRPY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 aiqsiglFPHWTVAQNIAtvpqlqkwsrsriddrteelmallgldvnlrhrYP--HQLSGGQQQRVGVARALAADPQVLL 157
Cdd:cd03223 75 -------LPLGTLREQLI---------------------------------YPwdDVLSGGEQQRLAFARLLLHKPKFVF 114
|
170 180 190
....*....|....*....|....*....|....*.
gi 581977852 158 MDEPFGALDPvtrgALQQEMTRIHRLLGRTIVLVTH 193
Cdd:cd03223 115 LDEATSALDE----ESEDRLYQLLKELGITVISVGH 146
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
15-232 |
7.28e-13 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 67.05 E-value: 7.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFS-----VLIGTSGSGKSTTLKMINRLVEHDsgvirfAGEEIRSLPvlelrrrmgyaiqSIGLFPH 89
Cdd:cd03237 8 KTLGEFTLEVEGGSISeseviGILGPNGIGKTTFIKMLAGVLKPD------EGDIEIELD-------------TVSYKPQ 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 90 WTVAQNIATVPQLQkwsRSRIDDRTE------ELMALLGLDVNLRHRYPhQLSGGQQQRVGVARALAADPQVLLMDEPFG 163
Cdd:cd03237 69 YIKADYEGTVRDLL---SSITKDFYThpyfktEIAKPLQIEQILDREVP-ELSGGELQRVAIAACLSKDADIYLLDEPSA 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 164 ALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQ-QGTPLEMLTAPANDFVQ 232
Cdd:cd03237 145 YLDVEQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIVFEGEPSVNgVANPPQSLRSGMNRFLK 214
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-214 |
8.17e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 68.81 E-value: 8.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFaGEEIrslpvlelrrRMGYAI 81
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV----------KLAYVD 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QS-IGLFPHWTVAQNIAtvpqlqkwsrsridDRTEELMaLLGLDVNLR-------------HRYPHQLSGGQQQRVGVAR 147
Cdd:TIGR03719 392 QSrDALDPNKTVWEEIS--------------GGLDIIK-LGKREIPSRayvgrfnfkgsdqQKKVGQLSGGERNRVHLAK 456
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQEMTRihrlLGRTIVLVTHD---IDealRLAEHLVLMDG-GEVV 214
Cdd:TIGR03719 457 TLKSGGNVLLLDEPTNDLDVETLRALEEALLN----FAGCAVVISHDrwfLD---RIATHILAFEGdSHVE 520
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
23-219 |
9.81e-13 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 68.54 E-value: 9.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 23 HFREGSFSVLIGTSGSGKSTTLKMINRLVEHD---SGVIRFAGEEIRSLpvlELRRRMGYAIQSIGLFPHWTVAQniatv 99
Cdd:TIGR00955 47 VAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIDAK---EMRAISAYVQQDDLFIPTLTVRE----- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 100 pQLQKWSRSRIDDRT---------EELMALLGLD--VNLRHRYPHQ---LSGGQQQRVGVARALAADPQVLLMDEPFGAL 165
Cdd:TIGR00955 119 -HLMFQAHLRMPRRVtkkekrervDEVLQALGLRkcANTRIGVPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGL 197
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 166 DPVTRGALQQEMTRIhRLLGRTIVLVTHD-IDEALRLAEHLVLMDGGEVVQQGTP 219
Cdd:TIGR00955 198 DSFMAYSVVQVLKGL-AQKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSP 251
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
17-211 |
1.78e-12 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 65.43 E-value: 1.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRR----MGYAIQSIGLFpHWTV 92
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRnrysVAYAAQKPWLL-NATV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 93 AQNIATVPQLQKWSRSRIDDRTEelmalLGLDVNLrhrYPH-----------QLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:cd03290 96 EENITFGSPFNKQRYKAVTDACS-----LQPDIDL---LPFgdqteigergiNLSGGQRQRICVARALYQNTNIVFLDDP 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 162 FGALDPVTRGALQQE-MTRIHRLLGRTIVLVTHDIdEALRLAEHLVLMDGG 211
Cdd:cd03290 168 FSALDIHLSDHLMQEgILKFLQDDKRTLVLVTHKL-QYLPHADWIIAMKDG 217
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
2-212 |
5.01e-12 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 66.15 E-value: 5.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK-AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYA 80
Cdd:PRK10522 323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRKLFSAV 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQL-QKWsrsriddrteelMALLGLDVNLRHRYPH----QLSGGQQQRVGVARALAADPQV 155
Cdd:PRK10522 403 FTDFHLFDQLLGPEGKPANPALvEKW------------LERLKMAHKLELEDGRisnlKLSKGQKKRLALLLALAEERDI 470
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDiDEALRLAEHLVLMDGGE 212
Cdd:PRK10522 471 LLLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQ 526
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
14-193 |
5.13e-12 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 63.82 E-value: 5.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 14 QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlPVLELRRRMGYAIQSIGLFPHWTVA 93
Cdd:PRK13540 14 QPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK-DLCTYQKQLCFVGHRSGINPYLTLR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 94 QNIatvpqLQKWSRSRIDDRTEELMALLGLDVNLrhRYP-HQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVtrgA 172
Cdd:PRK13540 93 ENC-----LYDIHFSPGAVGITELCRLFSLEHLI--DYPcGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDEL---S 162
|
170 180
....*....|....*....|...
gi 581977852 173 LQQEMTRI--HRLLGRTIVLVTH 193
Cdd:PRK13540 163 LLTIITKIqeHRAKGGAVLLTSH 185
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
19-213 |
9.51e-12 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 65.46 E-value: 9.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLE-LRRRMGYAI---QSIGLFPHWTVAQ 94
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrLARGLVYLPedrQSSGLYLDAPLAW 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 95 NIA--TVPQLQKWSRSRIDDRT-EELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPfgaldpvTRG 171
Cdd:PRK15439 361 NVCalTHNRRGFWIKPARENAVlERYRRALNIKFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEP-------TRG 433
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 581977852 172 ALQQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:PRK15439 434 VDVSARNDIYQLIrsiaaqNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
14-233 |
1.06e-11 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 64.11 E-value: 1.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 14 QKAVNDLNLHFREG--------SFSV-------LIGTSGSGKSTTLKMINRLVEHDsGVIRFAGEEIRSLPVLELRRRMG 78
Cdd:cd03289 2 QMTVKDLTAKYTEGgnavleniSFSIspgqrvgLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGVSWNSVPLQKWRKAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 79 YAIQSIGLFPHwTVAQNIatvPQLQKWSRSRIDDRTEELmallGLDVNLrHRYPHQL-----------SGGQQQRVGVAR 147
Cdd:cd03289 81 VIPQKVFIFSG-TFRKNL---DPYGKWSDEEIWKVAEEV----GLKSVI-EQFPGQLdfvlvdggcvlSHGHKQLMCLAR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 148 ALAADPQVLLMDEPFGALDPVTRGALQQemTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDGGevVQQGTPLEMLTAPA 227
Cdd:cd03289 152 SVLSKAKILLLDEPSAHLDPITYQVIRK--TLKQAFADCTVILSEHRIEAMLECQRFLVIEENK--VRQYDSIQKLLNEK 227
|
....*.
gi 581977852 228 NDFVQA 233
Cdd:cd03289 228 SHFKQA 233
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
4-222 |
1.57e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 65.38 E-value: 1.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 4 FSHVSKTfgAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLK-MINRLVEHDSGVIrfageeirslpvlELRRRMGYAIQ 82
Cdd:PLN03232 622 FSWDSKT--SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSV-------------VIRGSVAYVPQ 686
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 SIGLFpHWTVAQNIATVPQLQKWSRSRIDDRT---EELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMD 159
Cdd:PLN03232 687 VSWIF-NATVRENILFGSDFESERYWRAIDVTalqHDLDLLPGRDLTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFD 765
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 160 EPFGALDP-VTRGALQQEMTriHRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:PLN03232 766 DPLSALDAhVAHQVFDSCMK--DELKGKTRVLVTNQL-HFLPLMDRIILVSEGMIKEEGTFAEL 826
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
4-222 |
2.31e-11 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 63.34 E-value: 2.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 4 FSHVSktFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeirslpvlelrrRMGYAIQS 83
Cdd:cd03291 42 FSNLC--LVGAPVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSG-------------RISFSSQF 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHwTVAQNI---ATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDE 160
Cdd:cd03291 107 SWIMPG-TIKENIifgVSYDEYRYKSVVKACQLEEDITKFPEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDS 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 161 PFGALDPVTRGALQQEMtrIHRLLG-RTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:cd03291 186 PFGYLDVFTEKEIFESC--VCKLMAnKTRILVTSKM-EHLKKADKILILHEGSSYFYGTFSEL 245
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
19-239 |
3.11e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 64.41 E-value: 3.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREG--------SFSV-------LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQS 83
Cdd:PTZ00243 1313 GVQMRYREGlplvlrgvSFRIaprekvgIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQD 1392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHwTVAQNIAtvPQLQKWSrsriddrtEELMALLGLdVNLRHRYPHQLSG--------------GQQQRVGVARA- 148
Cdd:PTZ00243 1393 PVLFDG-TVRQNVD--PFLEASS--------AEVWAALEL-VGLRERVASESEGidsrvleggsnysvGQRQLMCMARAl 1460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 149 LAADPQVLLMDEPFGALDPvtrgAL--QQEMTRIHRLLGRTIVLVTHDIDEALRLaEHLVLMDGGEVVQQGTPLEMLTAP 226
Cdd:PTZ00243 1461 LKKGSGFILMDEATANIDP----ALdrQIQATVMSAFSAYTVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPRELVMNR 1535
|
250
....*....|....*.
gi 581977852 227 ANDF---VQAfFGRSE 239
Cdd:PTZ00243 1536 QSIFhsmVEA-LGRSE 1550
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
36-225 |
3.47e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 64.28 E-value: 3.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 36 SGSGKSTTlkminrlVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFpHWTVAQNI------ATVPQLQKWSR-S 108
Cdd:PTZ00265 1264 GGSGEDST-------VFKNSGKILLDGVDICDYNLKDLRNLFSIVSQEPMLF-NMSIYENIkfgkedATREDVKRACKfA 1335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 109 RIDDRTEELMALLGLDVNlrhRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTI 188
Cdd:PTZ00265 1336 AIDEFIESLPNKYDTNVG---PYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTI 1412
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 581977852 189 VLVTHDIdEALRLAEHLVLMDG----GEVVQ-QGTPLEMLTA 225
Cdd:PTZ00265 1413 ITIAHRI-ASIKRSDKIVVFNNpdrtGSFVQaHGTHEELLSV 1453
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
19-217 |
4.43e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 63.64 E-value: 4.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIrfageeirslpvlelrrrmgyaiqsiglfphWTvAQNIAT 98
Cdd:PTZ00243 678 DVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV-------------------------------WA-ERSIAY 725
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 VPQlQKW-----SRSRI----DDRTEEL------------MALL--GLDVNLRHRYPHqLSGGQQQRVGVARALAADPQV 155
Cdd:PTZ00243 726 VPQ-QAWimnatVRGNIlffdEEDAARLadavrvsqleadLAQLggGLETEIGEKGVN-LSGGQKARVSLARAVYANRDV 803
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 156 LLMDEPFGALDPVTrGALQQEMTRIHRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQG 217
Cdd:PTZ00243 804 YLLDDPLSALDAHV-GERVVEECFLGALAGKTRVLATHQV-HVVPRADYVVALGDGRVEFSG 863
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
15-213 |
5.96e-11 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 62.92 E-value: 5.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMI----------NRLVEHDSGVIRFAGEEIRSLPVL--ELRRRMGyaiq 82
Cdd:TIGR02633 274 KRVDDVSFSLRRGEILGVAGLVGAGRTELVQALfgaypgkfegNVFINGKPVDIRNPAQAIRAGIAMvpEDRKRHG---- 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 83 sigLFPHWTVAQNIaTVPQLQKWS-RSRIDDRTEELMALLGLD-VNLRHRYPH----QLSGGQQQRVGVARALAADPQVL 156
Cdd:TIGR02633 350 ---IVPILGVGKNI-TLSVLKSFCfKMRIDAAAELQIIGSAIQrLKVKTASPFlpigRLSGGNQQKAVLAKMLLTNPRVL 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 157 LMDEPfgaldpvTRGALQQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:TIGR02633 426 ILDEP-------TRGVDVGAKYEIYKLInqlaqeGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
17-219 |
7.43e-11 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 60.62 E-value: 7.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMI--NRLVEHDSGVIRFAGEEIRSLPVLElRRRMGyaiqsigLFPHWtvaQ 94
Cdd:cd03217 16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTImgHPKYEVTEGEILFKGEDITDLPPEE-RARLG-------IFLAF---Q 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 95 NIATVPQLqkwsrsriddRTEELmaLLGLDVNLrhryphqlSGGQQQRVGVARALAADPQVLLMDEPFGALDPVtrgALQ 174
Cdd:cd03217 85 YPPEIPGV----------KNADF--LRYVNEGF--------SGGEKKRNEILQLLLLEPDLAILDEPDSGLDID---ALR 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 581977852 175 QEMTRIHRLL--GRTIVLVTHdideALRLAEHLV-----LMDGGEVVQQGTP 219
Cdd:cd03217 142 LVAEVINKLReeGKSVLIITH----YQRLLDYIKpdrvhVLYDGRIVKSGDK 189
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
19-236 |
1.72e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 61.85 E-value: 1.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGeeirslpvlelrrRMGYAIQSIGLFPHwTVAQNI-- 96
Cdd:TIGR01271 444 NISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSG-------------RISFSPQTSWIMPG-TIKDNIif 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 97 -ATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALqQ 175
Cdd:TIGR01271 510 gLSYDEYRYTSVIKACQLEEDIALFPEKDKTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEKEI-F 588
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 176 EMTRIHRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEmLTAPANDFVQAFFG 236
Cdd:TIGR01271 589 ESCLCKLMSNKTRILVTSKL-EHLKKADKILLLHEGVCYFYGTFSE-LQAKRPDFSSLLLG 647
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
25-195 |
2.22e-10 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 60.07 E-value: 2.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 25 REGSFSVLIGTSGSGKSTTLK-----MINRLVEHDS-----GVIR-FAGEEIRSL--PVLELRRRMGYAIQSIGLFPhwt 91
Cdd:cd03236 24 REGQVLGLVGPNGIGKSTALKilagkLKPNLGKFDDppdwdEILDeFRGSELQNYftKLLEGDVKVIVKPQYVDLIP--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 92 vAQNIATVPQLQKwsrsRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDpvt 169
Cdd:cd03236 101 -KAVKGKVGELLK----KKDERgkLDELVDQLELR-HVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLD--- 171
|
170 180 190
....*....|....*....|....*....|.
gi 581977852 170 rgaLQQEMTR---IHRLL--GRTIVLVTHDI 195
Cdd:cd03236 172 ---IKQRLNAarlIRELAedDNYVLVVEHDL 199
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
22-214 |
2.73e-10 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 61.12 E-value: 2.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 22 LHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlpvlelrrRM------------------GYAIQS 83
Cdd:PRK11147 24 LHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVA--------RLqqdpprnvegtvydfvaeGIEEQA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHWTVAQNIATVP------QLQK----------WsrsRIDDRTEELMALLGLDvnlrhryPHQ----LSGGQQQRV 143
Cdd:PRK11147 96 EYLKRYHDISHLVETDPseknlnELAKlqeqldhhnlW---QLENRINEVLAQLGLD-------PDAalssLSGGWLRKA 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 144 GVARALAADPQVLLMDEPFGALDPVTRGALQQemtrihRLLG--RTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:PRK11147 166 ALGRALVSNPDVLLLDEPTNHLDIETIEWLEG------FLKTfqGSIIFISHDRSFIRNMATRIVDLDRGKLV 232
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
17-217 |
3.35e-10 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 58.81 E-value: 3.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 17 VNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHD---SGVIRFAGEEIRSLPVlELRRRMGYAIQSIGLFPHWTVA 93
Cdd:cd03233 23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAE-KYPGEIIYVSEEDVHFPTLTVR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 94 QNIATVPQLQKwsrsriddrteelmallgldvnlrHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTrgAL 173
Cdd:cd03233 102 ETLDFALRCKG------------------------NEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSST--AL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 581977852 174 Q-----QEMTRIHRLLgrTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:cd03233 156 EilkciRTMADVLKTT--TFVSLYQASDEIYDLFDKVLVLYEGRQIYYG 202
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
19-230 |
4.85e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 60.76 E-value: 4.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREG--------SFSV-------LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQS 83
Cdd:PLN03232 1239 DVHLRYRPGlppvlhglSFFVspsekvgVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQS 1318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHwTVAQNIATVPQLQK---WS---RSRIDDRTEElmALLGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PLN03232 1319 PVLFSG-TVRFNIDPFSEHNDadlWEaleRAHIKDVIDR--NPFGLDAEVSEG-GENFSVGQRQLLSLARALLRRSKILV 1394
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 158 MDEPFGALDpVTRGALQQEMTRiHRLLGRTIVLVTHDIDEALRLAEHLVLmDGGEVVQQGTPLEMLTAPANDF 230
Cdd:PLN03232 1395 LDEATASVD-VRTDSLIQRTIR-EEFKSCTMLVIAHRLNTIIDCDKILVL-SSGQVLEYDSPQELLSRDTSAF 1464
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
5-193 |
7.34e-10 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 59.89 E-value: 7.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 5 SHVSKTFGAQKAVNDLNLHFRE-------------GSFSVLIGTSGSGKSTTLKMI-NRLVEHD-SGVIRFAGEEirslP 69
Cdd:PLN03211 59 SNIKRILGHKPKISDETRQIQErtilngvtgmaspGEILAVLGPSGSGKSTLLNALaGRIQGNNfTGTILANNRK----P 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 70 VLELRRRMGYAIQSIGLFPHWTVAQNIATVPQLQKWSRSRIDDRT---EELMALLGL----DVNLRHRYPHQLSGGQQQR 142
Cdd:PLN03211 135 TKQILKRTGFVTQDDILYPHLTVRETLVFCSLLRLPKSLTKQEKIlvaESVISELGLtkceNTIIGNSFIRGISGGERKR 214
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 143 VGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLVTH 193
Cdd:PLN03211 215 VSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSLAQ-KGKTIVTSMH 264
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
19-193 |
2.23e-09 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 56.35 E-value: 2.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVlELRRRMGYAIQSIGLFPHWTVAQNiat 98
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRD-EYHQDLLYLGHQPGIKTELTALEN--- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 vpqLQKWSRSRIDDRTEELMALLGlDVNLRHR--YP-HQLSGGQQQRVGVARALAADPQVLLMDEPFGALDpvtrgalQQ 175
Cdd:PRK13538 95 ---LRFYQRLHGPGDDEALWEALA-QVGLAGFedVPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID-------KQ 163
|
170 180
....*....|....*....|....
gi 581977852 176 EMTRIHRLL------GRTIVLVTH 193
Cdd:PRK13538 164 GVARLEALLaqhaeqGGMVILTTH 187
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
85-213 |
2.71e-09 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 58.02 E-value: 2.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 85 GLFPHWTVAQNIaTVPQLQKWS-RSRIDDRTEELMALLGLDvNLRHRYPH------QLSGGQQQRVGVARALAADPQVLL 157
Cdd:PRK13549 351 GIVPVMGVGKNI-TLAALDRFTgGSRIDDAAELKTILESIQ-RLKVKTASpelaiaRLSGGNQQKAVLAKCLLLNPKILI 428
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581977852 158 MDEPfgaldpvTRGALQQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:PRK13549 429 LDEP-------TRGIDVGAKYEIYKLInqlvqqGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
27-202 |
2.80e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 55.07 E-value: 2.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 27 GSFSVLIGTSGSGKSTTLKMI-NRLVEHDSGVIRFAGEEIRSlpvlelrrrmgyaiqsiglfphwtvaqniatvpqlqkw 105
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALaRELGPPGGGVIYIDGEDILE-------------------------------------- 43
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 106 srsriddrteelMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQE-----MTRI 180
Cdd:smart00382 44 ------------EVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrlLLLL 111
|
170 180
....*....|....*....|..
gi 581977852 181 HRLLGRTIVLVTHDIDEALRLA 202
Cdd:smart00382 112 KSEKNLTVILTTNDEKDLGPAL 133
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
2-229 |
3.28e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 58.12 E-value: 3.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAV---NDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSG-VIRFAGEEIRSLPVLELRRRM 77
Cdd:PTZ00265 383 IQFKNVRFHYDTRKDVeiyKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGdIIINDSHNLKDINLKWWRSKI 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 78 GYAIQSIGLFPHwTVAQNI-----------ATVPQLQKWSRSRID--DRTEELMALLGLDVNL-------------RHRY 131
Cdd:PTZ00265 463 GVVSQDPLLFSN-SIKNNIkyslyslkdleALSNYYNEDGNDSQEnkNKRNSCRAKCAGDLNDmsnttdsneliemRKNY 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 132 -----------------------------------PHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQE 176
Cdd:PTZ00265 542 qtikdsevvdvskkvlihdfvsalpdkyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKT 621
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 581977852 177 MTRIHRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEMLTAPAND 229
Cdd:PTZ00265 622 INNLKGNENRITIIIAHRL-STIRYANTIFVLSNRERGSTVDVDIIGEDPTKD 673
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
135-223 |
3.65e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.03 E-value: 3.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 LSGGQQQRVGVARALAADPQVLLMDEPFGALDP-VTRGALQQEMTRIHRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEV 213
Cdd:TIGR00957 761 LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAhVGKHIFEHVIGPEGVLKNKTRILVTHGI-SYLPQVDVIIVMSGGKI 839
|
90
....*....|
gi 581977852 214 VQQGTPLEML 223
Cdd:TIGR00957 840 SEMGSYQELL 849
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
32-224 |
5.13e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 57.44 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 32 LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwTVAQNiatvpqLQKWSRSRID 111
Cdd:PLN03130 1270 IVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQAPVLFSG-TVRFN------LDPFNEHNDA 1342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 112 DRTEELMAL----------LGLDVNLRHRyPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDpVTRGALQQEMTR-- 179
Cdd:PLN03130 1343 DLWESLERAhlkdvirrnsLGLDAEVSEA-GENFSVGQRQLLSLARALLRRSKILVLDEATAAVD-VRTDALIQKTIRee 1420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 581977852 180 ---------IHRLlgRTIVlvthDIDEALrlaehlvLMDGGEVVQQGTPLEMLT 224
Cdd:PLN03130 1421 fksctmliiAHRL--NTII----DCDRIL-------VLDAGRVVEFDTPENLLS 1461
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
6-194 |
6.03e-09 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 56.87 E-value: 6.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 6 HVSKTFGAQKAV-NDLNLHFREGSFSVLIGTSGSGKSTTLKMInrlvehdSGVIR-FAGEEIRSLPVlelrrRMGYAIQS 83
Cdd:TIGR03719 9 RVSKVVPPKKEIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIM-------AGVDKdFNGEARPQPGI-----KVGYLPQE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 84 IGLFPHWTVAQNI-ATVPQLQKwsrsrIDDRTEELMALLG---------------------------LDVNLRH-----R 130
Cdd:TIGR03719 77 PQLDPTKTVRENVeEGVAEIKD-----ALDRFNEISAKYAepdadfdklaaeqaelqeiidaadawdLDSQLEIamdalR 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 131 YP------HQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMtriHRLLGrTIVLVTHD 194
Cdd:TIGR03719 152 CPpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHL---QEYPG-TVVAVTHD 217
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-173 |
6.77e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 56.67 E-value: 6.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLnlhfregSFSV-------LIGTSGSGKSTTLKMINRLVEHDSGVIRFaGEEIrslpvlelr 74
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDL-------SFSLppggivgIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV--------- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 75 rRMGYAIQS-IGLFPHWTVAQNIAtvpqlqkwsrsridDRTEELMaLLGLDVNLRhRY--------PHQ------LSGGQ 139
Cdd:PRK11819 388 -KLAYVDQSrDALDPNKTVWEEIS--------------GGLDIIK-VGNREIPSR-AYvgrfnfkgGDQqkkvgvLSGGE 450
|
170 180 190
....*....|....*....|....*....|....
gi 581977852 140 QQRVGVARALAADPQVLLMDEPFGALDPVTRGAL 173
Cdd:PRK11819 451 RNRLHLAKTLKQGGNVLLLDEPTNDLDVETLRAL 484
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
8-217 |
1.10e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 56.27 E-value: 1.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 8 SKTFGAQKAVNDLnlhFREGSFSVLIGTSGSGKSTTLKMINRLVEH----DSGVIRFAG---EEIRSlpvlELRRRMGYA 80
Cdd:TIGR00956 71 TKTFDILKPMDGL---IKPGELTVVLGRPGSGCSTLLKTIASNTDGfhigVEGVITYDGitpEEIKK----HYRGDVVYN 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 81 IQSIGLFPHWTVAQNIATVPQLQK-------WSR-SRIDDRTEELMALLGL----DVNLRHRYPHQLSGGQQQRVGVARA 148
Cdd:TIGR00956 144 AETDVHFPHLTVGETLDFAARCKTpqnrpdgVSReEYAKHIADVYMATYGLshtrNTKVGNDFVRGVSGGERKRVSIAEA 223
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 149 LAADPQVLLMDEPFGALDPVTrgALQ-----QEMTRIhrllGRTIVLVT--HDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:TIGR00956 224 SLGGAKIQCWDNATRGLDSAT--ALEfiralKTSANI----LDTTPLVAiyQCSQDAYELFDKVIVLYEGYQIYFG 293
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
112-223 |
1.13e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 55.79 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 112 DRTEELMALLGLDVNLRHRYPHqLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRlLGRTIVLV 191
Cdd:PRK10938 114 ARCEQLAQQFGITALLDRRFKY-LSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQ-SGITLVLV 191
|
90 100 110
....*....|....*....|....*....|..
gi 581977852 192 THDIDEALRLAEHLVLMDGGEVVQQGTPLEML 223
Cdd:PRK10938 192 LNRFDEIPDFVQFAGVLADCTLAETGEREEIL 223
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
2-170 |
1.16e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 55.79 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMI---------NRLVEHdsGVIRFAGEEIrslpvLE 72
Cdd:PRK10938 261 IVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLItgdhpqgysNDLTLF--GRRRGSGETI-----WD 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 73 LRRRMGYAIQSIGLfpHWTVAQNIATVpQLQKWSRS-----RIDDR----TEELMALLGLDVNLRHRYPHQLSGGQQQRV 143
Cdd:PRK10938 334 IKKHIGYVSSSLHL--DYRVSTSVRNV-ILSGFFDSigiyqAVSDRqqklAQQWLDILGIDKRTADAPFHSLSWGQQRLA 410
|
170 180
....*....|....*....|....*..
gi 581977852 144 GVARALAADPQVLLMDEPFGALDPVTR 170
Cdd:PRK10938 411 LIVRALVKHPTLLILDEPLQGLDPLNR 437
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
28-214 |
1.24e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 55.69 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 28 SFSV-------LIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSlpvlelrRRMGYAIQS-----------IGLFPH 89
Cdd:PRK11288 273 SFSVrageivgLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDI-------RSPRDAIRAgimlcpedrkaEGIIPV 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 90 WTVAQNIAtVPQLQKWSRSR--IDDRTEELMALLGL-DVNLRHRYPHQ----LSGGQQQRVGVARALAADPQVLLMDEPf 162
Cdd:PRK11288 346 HSVADNIN-ISARRHHLRAGclINNRWEAENADRFIrSLNIKTPSREQlimnLSGGNQQKAILGRWLSEDMKVILLDEP- 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 163 galdpvTRGALQQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHLVLMDGGEVV 214
Cdd:PRK11288 424 ------TRGIDVGAKHEIYNVIyelaaqGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
135-226 |
1.29e-08 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 56.17 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 LSGGQQQRVGVARALAAD-PQVL-LMDEPFGALDPVTRGALQQEMTRIhRLLGRTIVLVTHDiDEALRLAEHLVLM---- 208
Cdd:TIGR00630 489 LSGGEAQRIRLATQIGSGlTGVLyVLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHD-EDTIRAADYVIDIgpga 566
|
90 100
....*....|....*....|
gi 581977852 209 --DGGEVVQQGTPLEMLTAP 226
Cdd:TIGR00630 567 geHGGEVVASGTPEEILANP 586
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
18-214 |
1.83e-08 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 53.40 E-value: 1.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 18 NDLNLHFREGSFSVLIGTSGSGKSTTLKMI--NRLVEHDSGVIRFAGEEIRSlpvlELRRRMGYAIQSIGLFPHWTVaqn 95
Cdd:cd03232 24 NNISGYVKPGTLTALMGESGAGKTTLLDVLagRKTAGVITGEILINGRPLDK----NFQRSTGYVEQQDVHSPNLTV--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 96 iatvpqlqkwsrsriddrTEELMallgLDVNLRhryphQLSGGQQQRVGVARALAADPQVLLMDEPFGALDpvTRGALQQ 175
Cdd:cd03232 97 ------------------REALR----FSALLR-----GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLD--SQAAYNI 147
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 581977852 176 eMTRIHRLL--GRTIVLVTHDIDEAL-RLAEHLVLMD-GGEVV 214
Cdd:cd03232 148 -VRFLKKLAdsGQAILCTIHQPSASIfEKFDRLLLLKrGGKTV 189
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
19-225 |
2.76e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 55.34 E-value: 2.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwTVAQNIAT 98
Cdd:TIGR00957 1304 HINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPVLFSG-SLRMNLDP 1382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 99 VPQLQK---WSrsriddrTEELMALLGLDVNLRHRYPHQ-------LSGGQQQRVGVARALAADPQVLLMDEPFGALDPV 168
Cdd:TIGR00957 1383 FSQYSDeevWW-------ALELAHLKTFVSALPDKLDHEcaeggenLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1455
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 169 TRGALQQEM-TRIHRLlgrTIVLVTHDIDEALRLAEHLVLmDGGEVVQQGTPLEMLTA 225
Cdd:TIGR00957 1456 TDNLIQSTIrTQFEDC---TVLTIAHRLNTIMDYTRVIVL-DKGEVAEFGAPSNLLQQ 1509
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
25-195 |
2.76e-08 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 54.81 E-value: 2.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 25 REGSFSVLIGTSGSGKSTTLK-----MINRLVEHDSG-----VI-RFAGEEI----RSLPVLELRrrMGYAIQSIGLFPh 89
Cdd:PRK13409 97 KEGKVTGILGPNGIGKTTAVKilsgeLIPNLGDYEEEpswdeVLkRFRGTELqnyfKKLYNGEIK--VVHKPQYVDLIP- 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 90 wtvAQNIATVPQLQKwsrsRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDP 167
Cdd:PRK13409 174 ---KVFKGKVRELLK----KVDERgkLDEVVERLGLE-NILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDI 245
|
170 180 190
....*....|....*....|....*....|.
gi 581977852 168 VTR---GALQQEMTRihrllGRTIVLVTHDI 195
Cdd:PRK13409 246 RQRlnvARLIRELAE-----GKYVLVVEHDL 271
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
20-223 |
4.22e-08 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 53.37 E-value: 4.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 20 LNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHwTVAQNIAtv 99
Cdd:cd03288 40 VKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSG-SIRFNLD-- 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 100 PQlqkwsRSRIDDRTEELMALLGLDvNLRHRYPHQL-----------SGGQQQRVGVARALAADPQVLLMDEPFGALDPV 168
Cdd:cd03288 117 PE-----CKCTDDRLWEALEIAQLK-NMVKSLPGGLdavvteggenfSVGQRQLFCLARAFVRKSSILIMDEATASIDMA 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 169 TRGALQQ-EMTrihRLLGRTIVLVTHDIDEALRlAEHLVLMDGGEVVQQGTPLEML 223
Cdd:cd03288 191 TENILQKvVMT---AFADRTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLL 242
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
4-222 |
4.54e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 54.36 E-value: 4.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 4 FSHVSKtfGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLK-MINRL-VEHDSGVIrfageeirslpvleLRRRMGYAI 81
Cdd:PLN03130 622 FSWDSK--AERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELpPRSDASVV--------------IRGTVAYVP 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 QSIGLFpHWTVAQNI---ATVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLM 158
Cdd:PLN03130 686 QVSWIF-NATVRDNIlfgSPFDPERYERAIDVTALQHDLDLLPGGDLTEIGERGVNISGGQKQRVSMARAVYSNSDVYIF 764
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 159 DEPFGALDP-VTRGALQQEMTRihRLLGRTIVLVTHDIdEALRLAEHLVLMDGGEVVQQGTPLEM 222
Cdd:PLN03130 765 DDPLSALDAhVGRQVFDKCIKD--ELRGKTRVLVTNQL-HFLSQVDRIILVHEGMIKEEGTYEEL 826
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
2-195 |
8.70e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 53.25 E-value: 8.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGaqkavnDLNLHFREGSFS---VL--IGTSGSGKSTTLKMINRLVEHDSGVIrfageeirslpvlELRRR 76
Cdd:COG1245 342 VEYPDLTKSYG------GFSLEVEGGEIRegeVLgiVGPNGIGKTTFAKILAGVLKPDEGEV-------------DEDLK 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 MGYAIQSIGLFPHWTVAQNiatvpqLQKWSRSRIDDRT--EELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQ 154
Cdd:COG1245 403 ISYKPQYISPDYDGTVEEF------LRSANTDDFGSSYykTEIIKPLGLE-KLLDKNVKDLSGGELQRVAIAACLSRDAD 475
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 581977852 155 VLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDI 195
Cdd:COG1245 476 LYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDI 516
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
14-217 |
9.94e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 51.17 E-value: 9.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 14 QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMInrlvehdsgvirFAGEEIRSLpvlelrrrmgyaIQSIGLFPHwtva 93
Cdd:cd03238 8 VHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEG------------LYASGKARL------------ISFLPKFSR---- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 94 QNIATVPQLQkwsrsriddrteelmalLGLDVNLRHRYPHQ----LSGGQQQRVGVARALAADPQ--VLLMDEPFGALDP 167
Cdd:cd03238 60 NKLIFIDQLQ-----------------FLIDVGLGYLTLGQklstLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQ 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 168 VTrgaLQQEMTRIHRL--LGRTIVLVTHDiDEALRLAEHLVLM------DGGEVVQQG 217
Cdd:cd03238 123 QD---INQLLEVIKGLidLGNTVILIEHN-LDVLSSADWIIDFgpgsgkSGGKVVFSG 176
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
135-213 |
1.26e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 52.70 E-value: 1.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 LSGGQQQRVGVARALAADPQVLLMDEPfgaldpvTRGALQQEMTRIHRLL------GRTIVLVTHDIDEALRLAEHLVLM 208
Cdd:PRK10762 396 LSGGNQQKVAIARGLMTRPKVLILDEP-------TRGVDVGAKKEIYQLInqfkaeGLSIILVSSEMPEVLGMSDRILVM 468
|
....*
gi 581977852 209 DGGEV 213
Cdd:PRK10762 469 HEGRI 473
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
14-193 |
2.30e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 50.26 E-value: 2.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 14 QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPvlelRRRMGYAIQSIGLFPHWTVA 93
Cdd:PRK13541 13 QKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIA----KPYCTYIGHNLGLKLEMTVF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 94 QNiatvpqLQKWsrSRIDDRTEELMALL---GLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTR 170
Cdd:PRK13541 89 EN------LKFW--SEIYNSAETLYAAIhyfKLH-DLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR 159
|
170 180
....*....|....*....|...
gi 581977852 171 gALQQEMTRIHRLLGRTIVLVTH 193
Cdd:PRK13541 160 -DLLNNLIVMKANSGGIVLLSSH 181
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
24-220 |
2.34e-07 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 52.16 E-value: 2.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 24 FREGSFSVLIGTSGSGKSTTLKMI--NRLVEHDSGVIRFAGeeirsLPVLE--LRRRMGYAIQSIGLFPHWTVAQNIA-- 97
Cdd:PLN03140 903 FRPGVLTALMGVSGAGKTTLMDVLagRKTGGYIEGDIRISG-----FPKKQetFARISGYCEQNDIHSPQVTVRESLIys 977
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 98 ---TVP-QLQKWSRSRIDDrteELMALLGLDvNLRHR---YP--HQLSGGQQQRVGVARALAADPQVLLMDEPFGALDpV 168
Cdd:PLN03140 978 aflRLPkEVSKEEKMMFVD---EVMELVELD-NLKDAivgLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD-A 1052
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 581977852 169 TRGALQQEMTRIHRLLGRTIVLVTH----DIDEALrlaEHLVLMD-GGEVVQQGtPL 220
Cdd:PLN03140 1053 RAAAIVMRTVRNTVDTGRTVVCTIHqpsiDIFEAF---DELLLMKrGGQVIYSG-PL 1105
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
24-217 |
2.53e-07 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 52.03 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 24 FREGSFSVLIGTSGSGKSTTLkmiNRLVEH-DSGVIRfAGEEIRSLPVLE--LRRRMGYAIQSIGLFPHWTVAQNI---A 97
Cdd:TIGR00956 786 VKPGTLTALMGASGAGKTTLL---NVLAERvTTGVIT-GGDRLVNGRPLDssFQRSIGYVQQQDLHLPTSTVRESLrfsA 861
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 98 TVPQLQKWSRSRIDDRTEELMALLGLDvnlrhRYPHQLSG--------GQQQRVGVARALAADPQVLL-MDEPFGALDPV 168
Cdd:TIGR00956 862 YLRQPKSVSKSEKMEYVEEVIKLLEME-----SYADAVVGvpgeglnvEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQ 936
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 169 TRGALQQEMTRI--HrllGRTIVLVTHD-----IDEALRLaehLVLMDGGEVVQQG 217
Cdd:TIGR00956 937 TAWSICKLMRKLadH---GQAILCTIHQpsailFEEFDRL---LLLQKGGQTVYFG 986
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
19-217 |
3.66e-07 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 49.95 E-value: 3.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 19 DLNLHFREGSFSVLIGTSGSGKST----TLkminrlveHDSGVIRFageeIRSLPVLeLRRRMGY----AIQSI-GLFPH 89
Cdd:cd03270 13 NVDVDIPRNKLVVITGVSGSGKSSlafdTI--------YAEGQRRY----VESLSAY-ARQFLGQmdkpDVDSIeGLSPA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 90 WTVAQN-IATVPQLQKWSRSRIDDRTEELMALLGL--------DVNLRH----RYPHQLSGGQQQRVGVARALAADPQVL 156
Cdd:cd03270 80 IAIDQKtTSRNPRSTVGTVTEIYDYLRLLFARVGIrerlgflvDVGLGYltlsRSAPTLSGGEAQRIRLATQIGSGLTGV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977852 157 L--MDEPFGALDPVTRGALQQEMTRIhRLLGRTIVLVTHDiDEALRLAEHLVLM------DGGEVVQQG 217
Cdd:cd03270 160 LyvLDEPSIGLHPRDNDRLIETLKRL-RDLGNTVLVVEHD-EDTIRAADHVIDIgpgagvHGGEIVAQG 226
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
25-195 |
4.16e-07 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 51.32 E-value: 4.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 25 REGSFSVLIGTSGSGKSTTLK-----MINRLVEHDSG-----VI-RFAGEEIRSLpvleLRR------RMGYAIQSIGLF 87
Cdd:COG1245 97 KKGKVTGILGPNGIGKSTALKilsgeLKPNLGDYDEEpswdeVLkRFRGTELQDY----FKKlangeiKVAHKPQYVDLI 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 88 PhwtvAQNIATVPQLQKwsrsRIDDR--TEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGAL 165
Cdd:COG1245 173 P----KVFKGTVRELLE----KVDERgkLDELAEKLGLE-NILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYL 243
|
170 180 190
....*....|....*....|....*....|...
gi 581977852 166 DPVTR---GALQQEMTRIhrllGRTIVLVTHDI 195
Cdd:COG1245 244 DIYQRlnvARLIRELAEE----GKYVLVVEHDL 272
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
14-213 |
5.43e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 50.88 E-value: 5.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 14 QKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRRRmGYAI-----QSIGLFP 88
Cdd:PRK10982 261 QPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAINH-GFALvteerRSTGIYA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 89 HWTVAQN--IATVPQ-LQKW---SRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPF 162
Cdd:PRK10982 340 YLDIGFNslISNIRNyKNKVgllDNSRMKSDTQWVIDSMRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPT 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 581977852 163 GALDPVTRGALQQEMTRIHRlLGRTIVLVTHDIDEALRLAEHLVLMDGGEV 213
Cdd:PRK10982 420 RGIDVGAKFEIYQLIAELAK-KDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
20-167 |
6.05e-07 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 49.46 E-value: 6.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 20 LNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLpvlELRRRMGYAIQSIGLFPHWTVAQNIATV 99
Cdd:PRK13543 30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRG---DRSRFMAYLGHLPGLKADLSTLENLHFL 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 100 PQLQKWSRSRIDDRTEELMALLGLDVNLrhryPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALDP 167
Cdd:PRK13543 107 CGLHGRRAKQMPGSALAIVGLAGYEDTL----VRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-218 |
7.23e-07 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 49.64 E-value: 7.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMInrlVEHDS-----GVIRFAGEEIRSLPVlELRR 75
Cdd:CHL00131 7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVI---AGHPAykileGDILFKGESILDLEP-EERA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMG------YAIQSIGLfphwtvaqNIATVPQLQKWSRSRIDDRTE-----------ELMALLGLDVNLRHRYPHQ-LSG 137
Cdd:CHL00131 83 HLGiflafqYPIEIPGV--------SNADFLRLAYNSKRKFQGLPEldplefleiinEKLKLVGMDPSFLSRNVNEgFSG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 138 GQQQRVGVARALAADPQVLLMDEPFGALDPvtrGALQQEMTRIHRLLGRT--IVLVTHdideALRLAEHLV-----LMDG 210
Cdd:CHL00131 155 GEKKRNEILQMALLDSELAILDETDSGLDI---DALKIIAEGINKLMTSEnsIILITH----YQRLLDYIKpdyvhVMQN 227
|
....*...
gi 581977852 211 GEVVQQGT 218
Cdd:CHL00131 228 GKIIKTGD 235
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1-195 |
7.50e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 50.58 E-value: 7.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGaqkavnDLNLH-----FREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIrfageeirslpvlELRR 75
Cdd:PRK13409 340 LVEYPDLTKKLG------DFSLEveggeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV-------------DPEL 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 76 RMGYAIQSIGLFPHWTVAQNIATVPQlqKWSRSRIDdrtEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQV 155
Cdd:PRK13409 401 KISYKPQYIKPDYDGTVEDLLRSITD--DLGSSYYK---SEIIKPLQLE-RLLDKNVKDLSGGELQRVAIAACLSRDADL 474
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 581977852 156 LLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDI 195
Cdd:PRK13409 475 YLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDI 514
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
6-217 |
1.26e-06 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 49.04 E-value: 1.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 6 HVSKTFgaqKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEeirsLPVLelrrrmgyAIQSiG 85
Cdd:PRK13546 32 HKNKTF---FALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE----VSVI--------AISA-G 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 86 LFPHWTVAQNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEpfgAL 165
Cdd:PRK13546 96 LSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELG-EFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDE---AL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 581977852 166 DPVTRGALQQEMTRIHRL--LGRTIVLVTHDIDEALRLAEHLVLMDGGEVVQQG 217
Cdd:PRK13546 172 SVGDQTFAQKCLDKIYEFkeQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
24-204 |
1.35e-06 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 47.99 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 24 FREGsFSVLIGTSGSGKSTTLKMI-----------NRLVEHDSGVIRfAGEEIRSLPvLELRRRMG---YAIQSIGLFph 89
Cdd:cd03240 20 FFSP-LTLIVGQNGAGKTTIIEALkyaltgelppnSKGGAHDPKLIR-EGEVRAQVK-LAFENANGkkyTITRSLAIL-- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 90 wtvaQNIATVPQlqkwsrsriddrtEELMALLgldvnLRHRypHQLSGGQQQ------RVGVARALAADPQVLLMDEPFG 163
Cdd:cd03240 95 ----ENVIFCHQ-------------GESNWPL-----LDMR--GRCSGGEKVlasliiRLALAETFGSNCGILALDEPTT 150
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 581977852 164 ALDPVTR-GALQQEMTRIHRLLGRTIVLVTHDiDEALRLAEH 204
Cdd:cd03240 151 NLDEENIeESLAEIIEERKSQKNFQLIVITHD-EELVDAADH 191
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
121-242 |
1.38e-06 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 49.83 E-value: 1.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 121 LGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQ--VLLMDEPFGALDPVTRGALQQEMTRIhRLLGRTIVLVTHDiDEA 198
Cdd:PRK00635 463 LGLPYLTPERALATLSGGEQERTALAKHLGAELIgiTYILDEPSIGLHPQDTHKLINVIKKL-RDQGNTVLLVEHD-EQM 540
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 581977852 199 LRLAEHLVLMD------GGEVVQQGTPLEMLTapANDFVQAFFGRSELGV 242
Cdd:PRK00635 541 ISLADRIIDIGpgagifGGEVLFNGSPREFLA--KSDSLTAKYLRQELTI 588
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
2-166 |
1.05e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 46.81 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAgEEIrslpvlelrrRMGYAI 81
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWS-ENA----------NIGYYA 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 82 Q--------SIGLFpHWtvaqniatvpqLQKWSRSRIDDRTeeLMALLGL------DVNlrhRYPHQLSGGQQQRVGVAR 147
Cdd:PRK15064 389 QdhaydfenDLTLF-DW-----------MSQWRQEGDDEQA--VRGTLGRllfsqdDIK---KSVKVLSGGEKGRMLFGK 451
|
170
....*....|....*....
gi 581977852 148 ALAADPQVLLMDEPFGALD 166
Cdd:PRK15064 452 LMMQKPNVLVMDEPTNHMD 470
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
135-221 |
1.06e-05 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 46.93 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 LSGGQQQRVGVARAL---AADPQVLLMDEPFGAL--DPVtrgalQQEMTRIHRL--LGRTIVLVTHDIDeALRLAEHLVL 207
Cdd:TIGR00630 830 LSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLhfDDI-----KKLLEVLQRLvdKGNTVVVIEHNLD-VIKTADYIID 903
|
90 100
....*....|....*....|
gi 581977852 208 M------DGGEVVQQGTPLE 221
Cdd:TIGR00630 904 LgpeggdGGGTVVASGTPEE 923
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
2-214 |
1.11e-05 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 46.71 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 2 IEFSHVSKTFGAQK-----AVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIRFAGEEIRSLPVLELRrr 76
Cdd:COG4615 328 LELRGVTYRYPGEDgdegfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAYR-- 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 77 mgyaiqsiglfphwtvaQNIATV-------PQLQKWSRSRIDDRTEELMALLGLD--VNLRHRY--PHQLSGGQQQRVGV 145
Cdd:COG4615 406 -----------------QLFSAVfsdfhlfDRLLGLDGEADPARARELLERLELDhkVSVEDGRfsTTDLSQGQRKRLAL 468
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 146 ARALAADPQVLLMDEpFGA-LDPVTRgalqqemtRI--HRLL------GRTIVLVTHDiDEALRLAEHLVLMDGGEVV 214
Cdd:COG4615 469 LVALLEDRPILVFDE-WAAdQDPEFR--------RVfyTELLpelkarGKTVIAISHD-DRYFDLADRVLKMDYGKLV 536
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
7-194 |
1.22e-05 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 46.65 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 7 VSKTFGAQKAV-NDLNLHFREGSFSVLIGTSGSGKSTTLKmINRLVEHDsgvirFAGEEIRSLPVlelrrRMGYAIQSIG 85
Cdd:PRK11819 12 VSKVVPPKKQIlKDISLSFFPGAKIGVLGLNGAGKSTLLR-IMAGVDKE-----FEGEARPAPGI-----KVGYLPQEPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 86 LFPHWTVAQNI--ATVPQLQKWSR--------SRIDDRTEELMALLG-------------LDVNLRH-----RYPH---- 133
Cdd:PRK11819 81 LDPEKTVRENVeeGVAEVKAALDRfneiyaayAEPDADFDALAAEQGelqeiidaadawdLDSQLEIamdalRCPPwdak 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 581977852 134 --QLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMtriHRLLGrTIVLVTHD 194
Cdd:PRK11819 161 vtKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFL---HDYPG-TVVAVTHD 219
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
15-171 |
1.44e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 46.32 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 15 KAVNDLNLHFREGSFSVLIGTSGSGKsTTLKM--INRLVEHD-SGVIRFAGEEIRSLPVLE-LRRRMGYAIQ---SIGLF 87
Cdd:NF040905 274 KVVDDVSLNVRRGEIVGIAGLMGAGR-TELAMsvFGRSYGRNiSGTVFKDGKEVDVSTVSDaIDAGLAYVTEdrkGYGLN 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 88 PHWTVAQNIaTVPQLQKWSRSRIDDRTEELMALLGLDVNLRHRYPH------QLSGGQQQRVGVARALAADPQVLLMDEP 161
Cdd:NF040905 353 LIDDIKRNI-TLANLGKVSRRGVIDENEEIKVAEEYRKKMNIKTPSvfqkvgNLSGGNQQKVVLSKWLFTDPDVLILDEP 431
|
170
....*....|
gi 581977852 162 fgaldpvTRG 171
Cdd:NF040905 432 -------TRG 434
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
133-194 |
1.56e-05 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 44.27 E-value: 1.56e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 133 HQLSGGQQQRVGVARALA----ADPQVLLMDEPFGALDPVTRGALqQEMTRIHRLLGRTIVLVTHD 194
Cdd:cd03227 76 LQLSGGEKELSALALILAlaslKPRPLYILDEIDRGLDPRDGQAL-AEAILEHLVKGAQVIVITHL 140
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
1-206 |
1.77e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 46.39 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTF-GAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVIrfageeIRSLPVlelrrRMGY 79
Cdd:PLN03073 508 IISFSDASFGYpGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTV------FRSAKV-----RMAV 576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQsiglfpHWTVAQNIATVPQL--QKWSRSRIDDRTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLL 157
Cdd:PLN03073 577 FSQ------HHVDGLDLSSNPLLymMRCFPGVPEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILL 650
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 581977852 158 MDEPFGALDPVTRGALQQEMTrihrLLGRTIVLVTHDidealrlaEHLV 206
Cdd:PLN03073 651 LDEPSNHLDLDAVEALIQGLV----LFQGGVLMVSHD--------EHLI 687
|
|
| CBS |
pfam00571 |
CBS domain; CBS domains are small intracellular modules that pair together to form a stable ... |
250-307 |
2.29e-05 |
|
CBS domain; CBS domains are small intracellular modules that pair together to form a stable globular domain. This family represents a single CBS domain. Pairs of these domains have been termed a Bateman domain. CBS domains have been shown to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet. CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role making proteins sensitive to adenosyl carrying ligands. The region containing the CBS domains in Cystathionine-beta synthase is involved in regulation by S-AdoMet. CBS domain pairs from AMPK bind AMP or ATP. The CBS domains from IMPDH and the chloride channel CLC2 bind ATP.
Pssm-ID: 425756 [Multi-domain] Cd Length: 57 Bit Score: 41.43 E-value: 2.29e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 250 VGDYVRRHEQVggdaLAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLLSE 307
Cdd:pfam00571 1 VKDIMTKDVVT----VSPDTTLEEALELMREHGISRLPVVDEDGKLVGIVTLKDLLRA 54
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-194 |
2.49e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 45.65 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVSKTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVI--------------RFAGEEIR 66
Cdd:PRK15064 1 MLSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVsldpnerlgklrqdQFAFEEFT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 67 SLPVLelrrRMGYAiqsiglfPHWTVAQniatvpqlqkwSRSRI--------DD---------------------RTEEL 117
Cdd:PRK15064 81 VLDTV----IMGHT-------ELWEVKQ-----------ERDRIyalpemseEDgmkvadlevkfaemdgytaeaRAGEL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 118 maLLGLDVNLRHRYP--HQLSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEmtrihrLLGR--TIVLVTH 193
Cdd:PRK15064 139 --LLGVGIPEEQHYGlmSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDV------LNERnsTMIIISH 210
|
.
gi 581977852 194 D 194
Cdd:PRK15064 211 D 211
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
135-210 |
4.93e-05 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 43.33 E-value: 4.93e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 135 LSGGQQQRVGVARALAADPQVLLMDEPFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDG 210
Cdd:cd03222 72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFEG 147
|
|
| CBS_pair_SF |
cd02205 |
Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily; The CBS ... |
265-315 |
1.30e-04 |
|
Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).
Pssm-ID: 341358 [Multi-domain] Cd Length: 113 Bit Score: 40.69 E-value: 1.30e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 265 LAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL----SEALPGETTV 315
Cdd:cd02205 7 VDPDTTVREALELMAENGIGALPVVDDDGKLVGIVTERDILralvEGGLALDTPV 61
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
113-166 |
1.31e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 43.70 E-value: 1.31e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 581977852 113 RTEELMALLGLDVNLRHRYPHQLSGGQQQRVGVARALAADPQVLLMDEPFGALD 166
Cdd:PLN03073 323 RAASILAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
135-227 |
1.78e-04 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 43.09 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 LSGGQQQRVGVARALAADpqvlLM------DEPfgaldpvTRGALQQEMTR----IHRL--LGRTIVLVTHDiDEALRLA 202
Cdd:COG0178 486 LSGGEAQRIRLATQIGSG----LVgvlyvlDEP-------SIGLHQRDNDRlietLKRLrdLGNTVIVVEHD-EDTIRAA 553
|
90 100 110
....*....|....*....|....*....|.
gi 581977852 203 EHLVLM------DGGEVVQQGTPLEMLTAPA 227
Cdd:COG0178 554 DYIIDIgpgageHGGEVVAQGTPEEILKNPD 584
|
|
| COG3448 |
COG3448 |
CBS-domain-containing membrane protein [Signal transduction mechanisms]; |
265-311 |
2.20e-04 |
|
CBS-domain-containing membrane protein [Signal transduction mechanisms];
Pssm-ID: 442671 [Multi-domain] Cd Length: 136 Bit Score: 40.62 E-value: 2.20e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 581977852 265 LAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLLSEALPG 311
Cdd:COG3448 15 VSPDTTLREALELMREHGIRGLPVVDEDGRLVGIVTERDLLRALLPD 61
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
135-219 |
2.46e-04 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 41.83 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 135 LSGGQQQRVGVARAL---AADPQVLLMDEPFGALDPvtrGALQQEMTRIHRL--LGRTIVLVTHDIDeALRLAEHLVLM- 208
Cdd:cd03271 170 LSGGEAQRIKLAKELskrSTGKTLYILDEPTTGLHF---HDVKKLLEVLQRLvdKGNTVVVIEHNLD-VIKCADWIIDLg 245
|
90
....*....|....*.
gi 581977852 209 -----DGGEVVQQGTP 219
Cdd:cd03271 246 peggdGGGQVVASGTP 261
|
|
| CBS |
COG0517 |
CBS domain [Signal transduction mechanisms]; |
179-305 |
3.74e-04 |
|
CBS domain [Signal transduction mechanisms];
Pssm-ID: 440283 [Multi-domain] Cd Length: 128 Bit Score: 39.85 E-value: 3.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 179 RIHRLLGRTIVLVTHD--IDEALRL-AEH-----LVLMDGGEVVqqGtpleMLTApaNDFVQAFFGRselGVRLLSLRsV 250
Cdd:COG0517 2 KVKDIMTTDVVTVSPDatVREALELmSEKrigglPVVDEDGKLV--G----IVTD--RDLRRALAAE---GKDLLDTP-V 69
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 581977852 251 GDYVRRHEQVggdaLAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL 305
Cdd:COG0517 70 SEVMTRPPVT----VSPDTSLEEAAELMEEHKIRRLPVVDDDGRLVGIITIKDLL 120
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
182-226 |
3.97e-04 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 41.98 E-value: 3.97e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 581977852 182 RLLGRTIVLVTHDiDEALRLAEHLVlmD--------GGEVVQQGTPLEMLTAP 226
Cdd:PRK00349 538 RDLGNTLIVVEHD-EDTIRAADYIV--DigpgagvhGGEVVASGTPEEIMKNP 587
|
|
| CBS_pair_SF |
cd02205 |
Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily; The CBS ... |
187-305 |
4.83e-04 |
|
Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).
Pssm-ID: 341358 [Multi-domain] Cd Length: 113 Bit Score: 39.15 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 187 TIVLVTHDIDEALRL-AEH-----LVLMDGGEVVqqGtpleMLTApaNDFVQAFFGRselgvRLLSLRSVGDYVRRHeqv 260
Cdd:cd02205 5 VTVDPDTTVREALELmAENgigalPVVDDDGKLV--G----IVTE--RDILRALVEG-----GLALDTPVAEVMTPD--- 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 581977852 261 gGDALAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL 305
Cdd:cd02205 69 -VITVSPDTDLEEALELMLEHGIRRLPVVDDDGKLVGIVTRRDIL 112
|
|
| YtoI |
COG4109 |
Predicted transcriptional regulator containing CBS domains [Transcription]; |
250-305 |
6.18e-04 |
|
Predicted transcriptional regulator containing CBS domains [Transcription];
Pssm-ID: 443285 [Multi-domain] Cd Length: 135 Bit Score: 39.13 E-value: 6.18e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 581977852 250 VGDYVRRHEQVggdALAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL 305
Cdd:COG4109 18 VEDIMTLEDVA---TLSEDDTVEDALELLEKTGHSRFPVVDENGRLVGIVTSKDIL 70
|
|
| CBS_arch_repeat1 |
cd17777 |
CBS pair domains found in archeal proteins, repeat 1; CBS pair domains found in archeal ... |
213-306 |
7.59e-04 |
|
CBS pair domains found in archeal proteins, repeat 1; CBS pair domains found in archeal proteins that contain 2 repeats. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here.
Pssm-ID: 341413 [Multi-domain] Cd Length: 137 Bit Score: 38.86 E-value: 7.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 213 VVQQGTPLEMLTApaNDFVQAFFGRSELGV----------RLLSLRSVGDYVRRHEQVggdaLAEEMTLRDALSVFVARG 282
Cdd:cd17777 38 VVDENKLEGILSA--RDLVSYLGGGCLFKIvesrhqgdlySALNREVVETIMTPNPVY----VYEDSDLIEALTIMVTRG 111
|
90 100
....*....|....*....|....
gi 581977852 283 CDVLPVVDQQGTPCGTLHFRDLLS 306
Cdd:cd17777 112 IGSLPVVDRDGRPVGIVTERDLVL 135
|
|
| COG3448 |
COG3448 |
CBS-domain-containing membrane protein [Signal transduction mechanisms]; |
177-305 |
9.80e-04 |
|
CBS-domain-containing membrane protein [Signal transduction mechanisms];
Pssm-ID: 442671 [Multi-domain] Cd Length: 136 Bit Score: 38.69 E-value: 9.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 177 MTRIHRLLGRTIVLVTHD--IDEALRL-AEH-----LVLMDGGEVVqqGtpleMLTApaNDFVQAFFGRSELGV-RLLSL 247
Cdd:COG3448 1 AMTVRDIMTRDVVTVSPDttLREALELmREHgirglPVVDEDGRLV--G----IVTE--RDLLRALLPDRLDELeERLLD 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 581977852 248 RSVGDYVRRHEQVggdaLAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL 305
Cdd:COG3448 73 LPVEDVMTRPVVT----VTPDTPLEEAAELMLEHGIHRLPVVDDDGRLVGIVTRTDLL 126
|
|
| COG2524 |
COG2524 |
Predicted transcriptional regulator, contains C-terminal CBS domains [Transcription]; |
267-305 |
1.57e-03 |
|
Predicted transcriptional regulator, contains C-terminal CBS domains [Transcription];
Pssm-ID: 442013 [Multi-domain] Cd Length: 206 Bit Score: 39.10 E-value: 1.57e-03
10 20 30
....*....|....*....|....*....|....*....
gi 581977852 267 EEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLL 305
Cdd:COG2524 165 EDDSLEEALRLMLEHGIGRLPVVDDDGKLVGIITRTDIL 203
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
1-210 |
2.08e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 39.73 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 1 MIEFSHVS-KTFGAQKAVNDLNLHFREGSFSVLIGTSGSGKSTTLKMINRLVEHDSGVirfageeiRSLPVlelRRRMGY 79
Cdd:TIGR00954 451 GIKFENIPlVTPNGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGR--------LTKPA---KGKLFY 519
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 80 AIQSiglfPHWTVA----QNIATVPQLQKWSRSRIDDRTEELMALLGLDvNLRHR---------YPHQLSGGQQQRVGVA 146
Cdd:TIGR00954 520 VPQR----PYMTLGtlrdQIIYPDSSEDMKRRGLSDKDLEQILDNVQLT-HILEReggwsavqdWMDVLSGGEKQRIAMA 594
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 581977852 147 RALAADPQVLLMDEPFGALDPvtrgALQQEMTRIHRLLGRTIVLVTHDiDEALRLAEHLVLMDG 210
Cdd:TIGR00954 595 RLFYHKPQFAILDECTSAVSV----DVEGYMYRLCREFGITLFSVSHR-KSLWKYHEYLLYMDG 653
|
|
| PRK01862 |
PRK01862 |
voltage-gated chloride channel ClcB; |
232-308 |
2.59e-03 |
|
voltage-gated chloride channel ClcB;
Pssm-ID: 234987 [Multi-domain] Cd Length: 574 Bit Score: 39.34 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977852 232 QAFFG--------RSELGVRLLSLRSVGDYVRRHeqvgGDALAEEMTLRDALSVFVARGCDVLPVVDQQGTP--CGTLHF 301
Cdd:PRK01862 488 GRFRGavalkditSDLLDKRDTTDKTAADYAHTP----FPLLTPDMPLGDALEHFMAFQGERLPVVESEASPtlAGVVYK 563
|
....*..
gi 581977852 302 RDLLSEA 308
Cdd:PRK01862 564 TSLLDAY 570
|
|
| COG2905 |
COG2905 |
Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains ... |
251-306 |
3.13e-03 |
|
Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains [Signal transduction mechanisms];
Pssm-ID: 442149 [Multi-domain] Cd Length: 124 Bit Score: 37.12 E-value: 3.13e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977852 251 GDYVRRHEQVGGDALA---------------EEMTLRDALSVFVARGCDVLPVVDqQGTPCGTLHFRDLLS 306
Cdd:COG2905 49 RDLRRRVLAEGLDPLDtpvsevmtrppitvsPDDSLAEALELMEEHRIRHLPVVD-DGKLVGIVSITDLLR 118
|
|
| COG2905 |
COG2905 |
Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains ... |
265-309 |
4.65e-03 |
|
Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains [Signal transduction mechanisms];
Pssm-ID: 442149 [Multi-domain] Cd Length: 124 Bit Score: 36.35 E-value: 4.65e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 581977852 265 LAEEMTLRDALSVFVARGCDVLPVVDQQGTPCGTLHFRDLLSEAL 309
Cdd:COG2905 12 VSPDATVREAARLMTEKGVGSLVVVDDDGRLVGIITDRDLRRRVL 56
|
|
| VirB4 |
COG3451 |
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ... |
20-47 |
9.58e-03 |
|
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain] Cd Length: 546 Bit Score: 37.62 E-value: 9.58e-03
10 20
....*....|....*....|....*....
gi 581977852 20 LNLHFREGSFSVLI-GTSGSGKSTTLKMI 47
Cdd:COG3451 196 FDFHDGLDNGNTLIlGPSGSGKSFLLKLL 224
|
|
| |
