|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05632 |
PRK05632 |
phosphate acetyltransferase; Reviewed |
1-710 |
0e+00 |
|
phosphate acetyltransferase; Reviewed
Pssm-ID: 235537 [Multi-domain] Cd Length: 684 Bit Score: 1291.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 1 MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPraggnapdqttaivranssvpaaePLKMSHVESLLSS 80
Cdd:PRK05632 1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLAS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 81 NQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGG 160
Cdd:PRK05632 57 GQLDELLEEIVARYHALAKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSFGG 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 161 AKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVvkvDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNA 240
Cdd:PRK05632 137 AKNANILGVIINKLNAPVDEQGRTRPDLSEIFDDSSKANV---DPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAKHLGA 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 241 TVVNEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCER 320
Cdd:PRK05632 214 TVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAKLCEG 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 321 AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINAD-WIESLTATSERSRRLSPPAFRYQLTELA 399
Cdd:PRK05632 294 AFETGLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQLTERA 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 400 RKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKG 479
Cdd:PRK05632 374 RAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELRKHKG 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 480 MTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPD 559
Cdd:PRK05632 454 MTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAVNPD 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 560 PTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKA 639
Cdd:PRK05632 534 PTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVARSKA 613
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977824 640 PNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSS 710
Cdd:PRK05632 614 PNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
|
|
| PtaN |
COG0857 |
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; |
1-714 |
0e+00 |
|
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
Pssm-ID: 440618 [Multi-domain] Cd Length: 697 Bit Score: 839.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 1 MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGNAPDQTTAIVRANSSVPA----AEPLKMSHVES 76
Cdd:COG0857 1 MMKSIYIASTEPGSGKTSVALGLARALQRKGLRVGYFKPIGQSLVGGGERDEDVELIREHLGLDLpyedASPVTLDEVET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 77 LLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKH-QFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTR 155
Cdd:COG0857 81 LLAEGDPDELLERIVERYEALAAECDVVLVEGSDPTGVGsPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLLAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 156 SSFGGaKNTNITGVIVNKLNAPVDEQGRTrpDLSEIFddsskakvvkvdpaklqESSPLPVLGAVPWSFDLIATRAIDMA 235
Cdd:COG0857 161 DEFRG-EGARVLGVIINRVPPEKLEEVRE--ALRPFL-----------------EGSGIPVLGVIPENPELAAPTVRDLA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 236 RHLNATVVNEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGV-EIGALLLTGGYEMDARI 314
Cdd:COG0857 221 EALGAEVLNGGELLDRRVESVVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGTpSIAGLILTGGLPPDPAV 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 315 SKLCERAFATgLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERsrRLSPPAFRYQ 394
Cdd:COG0857 301 LRLAEGLGQT-LPILSVELDTYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSRLGLPRS--RLSPPAFFYY 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 395 LTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVARLVEL 474
Cdd:COG0857 378 LLERAARAAKRIVLPEGGEDRRILAAAICLLRRIAACVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAAEVYL 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 475 RKSKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDC 554
Cdd:COG0857 458 RRRKKKGVTVAAAQLEDDVVLYTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVVVGDC 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 555 AINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADV 634
Cdd:COG0857 538 ACAPNPPPEELALAAIISSSSAAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAAAADV 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 635 AKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSSQQQQ 714
Cdd:COG0857 618 VVAKAKPSPVAGAAAAFVFPFLDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQQQAA 697
|
|
| pta |
TIGR00651 |
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ... |
406-706 |
9.44e-176 |
|
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]
Pssm-ID: 273196 [Multi-domain] Cd Length: 303 Bit Score: 503.89 E-value: 9.44e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 406 VVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAasQGVELGAGIEIVDPEVV---RESYVARLVELRKSKGMTE 482
Cdd:TIGR00651 1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKA--AGCNLDLGHVVIIDPDVspdRESYAERYVELRKHKGMTE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 483 TVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTA 562
Cdd:TIGR00651 79 AQARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 563 EQLAEIAIQSAESAIAFG-IEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPN 641
Cdd:TIGR00651 159 EQLAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPN 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977824 642 SPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 706
Cdd:TIGR00651 239 SPVAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAITA 303
|
|
| PTA_PTB |
pfam01515 |
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ... |
391-706 |
1.04e-159 |
|
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.
Pssm-ID: 396207 [Multi-domain] Cd Length: 318 Bit Score: 463.71 E-value: 1.04e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 391 FRYQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGaGIEIVDPEVVR--ESYV 468
Cdd:pfam01515 1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDLD-GIEIVDPETSPrlEEYA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 469 ARLVELRKSKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQV 548
Cdd:pfam01515 80 DFYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 549 YVYGDCAINPDPTAEQLAEIAIQSAESAIAFG-IEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYD 627
Cdd:pfam01515 160 LFFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFD 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977824 628 AAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 706
Cdd:pfam01515 240 AALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAITA 318
|
|
| DTBS |
cd03109 |
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ... |
3-194 |
1.45e-29 |
|
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.
Pssm-ID: 349763 [Multi-domain] Cd Length: 189 Bit Score: 115.74 E-value: 1.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 3 RIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGNAPDqtTAIVRANSSVP----AAEPLKMSHVES-L 77
Cdd:cd03109 1 KTLFVTGTDTDVGKTVVSAGLARALRKKGIKVGYLKPVQTGCPGLEDSD--AELLRKLAGLLldleLINPYRFEAPLSpH 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 78 LSSNQ--KDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTR 155
Cdd:cd03109 79 LAAELegRDIDLEEIVRALEELAKSYDVVLVEGAGGLLVPLTEGYLNADLARALGLPVILVARGGLGTINHTLLTLEALK 158
|
170 180 190
....*....|....*....|....*....|....*....
gi 581977824 156 SsfggaKNTNITGVIVNKlnapVDEQGRTRPDLSEIFDD 194
Cdd:cd03109 159 S-----RGLDVAGVVLNG----IPPEPEAEADNAETLKE 188
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05632 |
PRK05632 |
phosphate acetyltransferase; Reviewed |
1-710 |
0e+00 |
|
phosphate acetyltransferase; Reviewed
Pssm-ID: 235537 [Multi-domain] Cd Length: 684 Bit Score: 1291.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 1 MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPraggnapdqttaivranssvpaaePLKMSHVESLLSS 80
Cdd:PRK05632 1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLAS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 81 NQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGG 160
Cdd:PRK05632 57 GQLDELLEEIVARYHALAKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSFGG 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 161 AKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVvkvDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNA 240
Cdd:PRK05632 137 AKNANILGVIINKLNAPVDEQGRTRPDLSEIFDDSSKANV---DPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAKHLGA 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 241 TVVNEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCER 320
Cdd:PRK05632 214 TVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAKLCEG 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 321 AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINAD-WIESLTATSERSRRLSPPAFRYQLTELA 399
Cdd:PRK05632 294 AFETGLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQLTERA 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 400 RKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKG 479
Cdd:PRK05632 374 RAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELRKHKG 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 480 MTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPD 559
Cdd:PRK05632 454 MTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAVNPD 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 560 PTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKA 639
Cdd:PRK05632 534 PTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVARSKA 613
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977824 640 PNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSS 710
Cdd:PRK05632 614 PNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
|
|
| PtaN |
COG0857 |
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; |
1-714 |
0e+00 |
|
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
Pssm-ID: 440618 [Multi-domain] Cd Length: 697 Bit Score: 839.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 1 MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGNAPDQTTAIVRANSSVPA----AEPLKMSHVES 76
Cdd:COG0857 1 MMKSIYIASTEPGSGKTSVALGLARALQRKGLRVGYFKPIGQSLVGGGERDEDVELIREHLGLDLpyedASPVTLDEVET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 77 LLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKH-QFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTR 155
Cdd:COG0857 81 LLAEGDPDELLERIVERYEALAAECDVVLVEGSDPTGVGsPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLLAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 156 SSFGGaKNTNITGVIVNKLNAPVDEQGRTrpDLSEIFddsskakvvkvdpaklqESSPLPVLGAVPWSFDLIATRAIDMA 235
Cdd:COG0857 161 DEFRG-EGARVLGVIINRVPPEKLEEVRE--ALRPFL-----------------EGSGIPVLGVIPENPELAAPTVRDLA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 236 RHLNATVVNEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGV-EIGALLLTGGYEMDARI 314
Cdd:COG0857 221 EALGAEVLNGGELLDRRVESVVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGTpSIAGLILTGGLPPDPAV 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 315 SKLCERAFATgLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERsrRLSPPAFRYQ 394
Cdd:COG0857 301 LRLAEGLGQT-LPILSVELDTYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSRLGLPRS--RLSPPAFFYY 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 395 LTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVARLVEL 474
Cdd:COG0857 378 LLERAARAAKRIVLPEGGEDRRILAAAICLLRRIAACVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAAEVYL 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 475 RKSKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDC 554
Cdd:COG0857 458 RRRKKKGVTVAAAQLEDDVVLYTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVVVGDC 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 555 AINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADV 634
Cdd:COG0857 538 ACAPNPPPEELALAAIISSSSAAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAAAADV 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 635 AKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSSQQQQ 714
Cdd:COG0857 618 VVAKAKPSPVAGAAAAFVFPFLDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQQQAA 697
|
|
| pta |
TIGR00651 |
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ... |
406-706 |
9.44e-176 |
|
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]
Pssm-ID: 273196 [Multi-domain] Cd Length: 303 Bit Score: 503.89 E-value: 9.44e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 406 VVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAasQGVELGAGIEIVDPEVV---RESYVARLVELRKSKGMTE 482
Cdd:TIGR00651 1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKA--AGCNLDLGHVVIIDPDVspdRESYAERYVELRKHKGMTE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 483 TVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTA 562
Cdd:TIGR00651 79 AQARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 563 EQLAEIAIQSAESAIAFG-IEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPN 641
Cdd:TIGR00651 159 EQLAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPN 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 581977824 642 SPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 706
Cdd:TIGR00651 239 SPVAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAITA 303
|
|
| Pta |
COG0280 |
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production ... |
390-708 |
3.61e-169 |
|
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production and conversion];
Pssm-ID: 440049 [Multi-domain] Cd Length: 320 Bit Score: 487.65 E-value: 3.61e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 390 AFRYQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGaGIEIVDPE--VVRESY 467
Cdd:COG0280 1 KFFRPLIERAKAAPKRIVFAEGEDERVLRAAQEALDEGLAEPILVGRPEKIEARAEELGLDLS-GFEIIDPEdsPRYEEY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 468 VARLVELRKSKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQ 547
Cdd:COG0280 80 AEAYYELRKRKGVTPEEARELVRDAAYFAAMMVRLGEADGLVKGAVGTTADLLRPVLQIIGLRPGVKRVSHVFLMELPDR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 548 VYVYGDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYD 627
Cdd:COG0280 160 LLFITDTAVNIDPTAEQLADIAINAADTARAFGIEPKVALLSASEFGSPKGPSTDKVREATKMARGQIPDLEVDGELQFD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 628 AAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAI 707
Cdd:COG0280 240 AALSPEAAKRKGPDSPVAGDANVLVFPDLEAGNILYKLLQRLAGAEAIGPILLGLAKPVHLLSRGDSVRDIVNSIALAAV 319
|
.
gi 581977824 708 Q 708
Cdd:COG0280 320 Q 320
|
|
| PTA_PTB |
pfam01515 |
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ... |
391-706 |
1.04e-159 |
|
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.
Pssm-ID: 396207 [Multi-domain] Cd Length: 318 Bit Score: 463.71 E-value: 1.04e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 391 FRYQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGaGIEIVDPEVVR--ESYV 468
Cdd:pfam01515 1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDLD-GIEIVDPETSPrlEEYA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 469 ARLVELRKSKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQV 548
Cdd:pfam01515 80 DFYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 549 YVYGDCAINPDPTAEQLAEIAIQSAESAIAFG-IEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYD 627
Cdd:pfam01515 160 LFFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFD 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977824 628 AAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 706
Cdd:pfam01515 240 AALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAITA 318
|
|
| eutD |
PRK09653 |
phosphotransacetylase; |
394-712 |
1.27e-153 |
|
phosphotransacetylase;
Pssm-ID: 236609 [Multi-domain] Cd Length: 324 Bit Score: 448.14 E-value: 1.27e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 394 QLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELgAGIEIVDPEVV--RESYVARL 471
Cdd:PRK09653 6 SLKEKAKGKKKKIVLPEGEDERVLKAAKRLQKEGLVEPILLGNPEEIRAKAKELGLDL-DGVEIIDPETYplLEEFAEAF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 472 VELRKSKGMTETvAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVY 551
Cdd:PRK09653 85 VELRKGKGTEED-AAELLKDPNYFGTMLVKLGKADGMVSGAIHSTADTLRPALQIIKTKPGVKTVSSVFIMVKGDERYIF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 552 GDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVM 631
Cdd:PRK09653 164 ADCAVNPNPTAEQLAEIAINSAETAKAFGIDPKVAMLSFSTKGSAKGPEVDKVQEATEIAKELAPDLKIDGELQFDAAFV 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 632 ADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSSQ 711
Cdd:PRK09653 244 PEVAAKKAPGSPVAGKANVFVFPSLEAGNIGYKIAQRLGGFEAVGPILQGLNKPVNDLSRGCSVEDIYNLALITAAQAQG 323
|
.
gi 581977824 712 Q 712
Cdd:PRK09653 324 E 324
|
|
| PRK07232 |
PRK07232 |
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed |
370-708 |
1.22e-92 |
|
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
Pssm-ID: 235976 [Multi-domain] Cd Length: 752 Bit Score: 304.33 E-value: 1.22e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 370 ADW---IESLTATSERSRRLSPPAFryqltELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAAS 446
Cdd:PRK07232 408 ADMdayREKLEAFVYKTGLVMKPIF-----AKAKKDPKRVVFAEGEEERVLRAAQEVVDEGLAKPILIGRPEVIEARIKK 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 447 QGVEL--GAGIEIVDPEV--VRESYVARLVELRKSKGMTETVAREQLE-DNVVLGTLMLEQDEVDGLVSGAVHTTANTIR 521
Cdd:PRK07232 483 LGLDLkaGVDFEIVNPEDdpRYEEYWQYYYELLQRKGVTPEDARRLVRrDRTVIGAMMVARGDADAMICGLTGRYHEHLR 562
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 522 PPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDV 601
Cdd:PRK07232 563 PVRQVIGLRPGVHTAAAMNALLLKGGNLFIADTYVNEDPTAEELAEIALMAAEEVRRFGIEPRVALLSHSNFGSSDSPSA 642
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 602 EKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG 681
Cdd:PRK07232 643 RKMREAVELLRERAPDLEVDGEMHGDAALNEEIRKDLYPFSRLKGPANVLVMPNLEAANISYNLLKELGGGVTIGPILLG 722
|
330 340
....*....|....*....|....*..
gi 581977824 682 MRKPVNDLSRGALVDDIVYTIALTAIQ 708
Cdd:PRK07232 723 MAKPVHILTPSATVRRIVNMTALAVVD 749
|
|
| PRK12862 |
PRK12862 |
malic enzyme; Reviewed |
397-712 |
2.09e-68 |
|
malic enzyme; Reviewed
Pssm-ID: 183799 [Multi-domain] Cd Length: 763 Bit Score: 239.02 E-value: 2.09e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 397 ELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVEL--GAGIEIVDPEV--VRESYVARLV 472
Cdd:PRK12862 441 AAAKAAPKRVVFAEGEDERVLRAAQVVVDEGLAKPILIGRPAVIEARIERAGLRLrpGVDFEIVNPEDdpRYRDYWDTYH 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 473 ELRKSKGMTETVAREQL-EDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVY 551
Cdd:PRK12862 521 ALMGRKGVTPEMARREVrRRTTLIGAMMVKRGEADAMICGTEGRYERHLEFVLQVIGKRPGVRVYAAMSLLILPGRTLFL 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 552 GDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVM 631
Cdd:PRK12862 601 ADTHVNEDPTAEELAEITILAAEEVRRFGIEPKVALLSHSNFGSSDSPSARKMREALEILRERAPDLEVDGEMHGDAALD 680
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 632 ADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSA-DLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSS 710
Cdd:PRK12862 681 EELRDRIFPDSRLEGEANLLVFPNLDAANIAYNLLKTAAgNGLAVGPILLGAAKPVHILTPSATVRRIVNMTALAVADAN 760
|
..
gi 581977824 711 QQ 712
Cdd:PRK12862 761 AY 762
|
|
| PRK12861 |
PRK12861 |
malic enzyme; Reviewed |
397-713 |
1.03e-44 |
|
malic enzyme; Reviewed
Pssm-ID: 183798 [Multi-domain] Cd Length: 764 Bit Score: 171.61 E-value: 1.03e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 397 ELARKAGK-RVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAG--IEIVDPEVVRE--SYVARL 471
Cdd:PRK12861 441 QLVRDGGKaRIVFTEGEDERVLRAVQVIVDEKLARPILVGRPEVLLARIERFGLRLRLGqdVEVTNPEYDERfpQYWTTY 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 472 VELRKSKGMTETVAREQLEDNVVL-GTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYV 550
Cdd:PRK12861 521 WELRCRDGISKEMARVEMRRRLTLiGAMMVRLGDADGMICGTVGEYHNHLRFVDEVIGRKPGASTYAAMNILLLDQRTVA 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 551 YGDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAV 630
Cdd:PRK12861 601 LVDTHVNDNPDAEQIAEFTIAAARQMEWLNLTPKVALLSRSNFGSGSAASGVKMRRALEIVREQAPDLEADGEMHGDCAL 680
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 631 MADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSA-DLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQS 709
Cdd:PRK12861 681 DEGLRARLLPMSPLKGAANLLVCPNVDAGNIAYNLLKTEAgSNVAVGPFLLGVNAPVNILTSSATVRRIVNMAALTVIEA 760
|
....
gi 581977824 710 SQQQ 713
Cdd:PRK12861 761 NRNV 764
|
|
| AAA_26 |
pfam13500 |
AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis ... |
3-230 |
5.38e-38 |
|
AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.
Pssm-ID: 433259 [Multi-domain] Cd Length: 198 Bit Score: 140.09 E-value: 5.38e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 3 RIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGNAPDQTTAIVRANSSVPAAEPLKMSHVES-LLSSN 81
Cdd:pfam13500 1 RTLFVTGTDTGVGKTVVSLGLARALKRRGVKVGYWKPVQTGLVEDGDSELVKRLLGLDQSYEDPEPFRLSAPLSpHLAAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 82 QK--DVLMEEIIanyHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSsfg 159
Cdd:pfam13500 81 QEgvTIDLEKII---YELPADADPVVVEGAGGLLVPINEDLLNADIAANLGLPVILVARGGLGTINHTLLTLEALRQ--- 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581977824 160 gaKNTNITGVIVNKLNAPVDEQgrtrpdlseifddsskakvvkvdpaKLQESSPLPVLGAVPWSFDLIATR 230
Cdd:pfam13500 155 --RGIPVLGVILNGVPNPENVR-------------------------TIFAFGGVPVLGAVPYLPDLTAPT 198
|
|
| DRTGG |
pfam07085 |
DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated ... |
233-345 |
1.65e-30 |
|
DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated with CBS domains pfam00571, as well as the CbiA domain pfam01656. The function of this domain is unknown. It is named the DRTGG domain after some of the most conserved residues. This domain may be very distantly related to a pair of CBS domains. There are no significant sequence similarities, but its length and association with CBS domains supports this idea (Bateman A, pers. obs.).
Pssm-ID: 429285 [Multi-domain] Cd Length: 105 Bit Score: 115.29 E-value: 1.65e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 233 DMARHLNATVVNEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAmngveIGALLLTGGYEMDA 312
Cdd:pfam07085 1 DIARILGAEVLNGGDGLLRRVGKVVVGAMSVENMLKYLRPGDLVITPGDREDIQLAALEAG-----IAGLILTGGFEPSP 75
|
90 100 110
....*....|....*....|....*....|...
gi 581977824 313 RISKLCERAfatGLPVFMVNTNTWQTSLSLQSF 345
Cdd:pfam07085 76 EVLKLAEEL---GLPVLSTPYDTFTTASRINRA 105
|
|
| DTBS |
cd03109 |
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ... |
3-194 |
1.45e-29 |
|
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.
Pssm-ID: 349763 [Multi-domain] Cd Length: 189 Bit Score: 115.74 E-value: 1.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 3 RIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGNAPDqtTAIVRANSSVP----AAEPLKMSHVES-L 77
Cdd:cd03109 1 KTLFVTGTDTDVGKTVVSAGLARALRKKGIKVGYLKPVQTGCPGLEDSD--AELLRKLAGLLldleLINPYRFEAPLSpH 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 78 LSSNQ--KDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTR 155
Cdd:cd03109 79 LAAELegRDIDLEEIVRALEELAKSYDVVLVEGAGGLLVPLTEGYLNADLARALGLPVILVARGGLGTINHTLLTLEALK 158
|
170 180 190
....*....|....*....|....*....|....*....
gi 581977824 156 SsfggaKNTNITGVIVNKlnapVDEQGRTRPDLSEIFDD 194
Cdd:cd03109 159 S-----RGLDVAGVVLNG----IPPEPEAEADNAETLKE 188
|
|
| PRK07742 |
PRK07742 |
phosphate butyryltransferase; Validated |
391-712 |
1.12e-17 |
|
phosphate butyryltransferase; Validated
Pssm-ID: 236086 Cd Length: 299 Bit Score: 84.37 E-value: 1.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 391 FRYQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESyvAR 470
Cdd:PRK07742 3 LEHLIDQAAGQPKKTVAVAVAEDEEVIEAVAKAIELQLARFRLYGNQEKIMGMLQEHGLQTSEHIEIIHAQSSAEA--AE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 471 LVELRKSKGmtetvareqlednvvlgtlmleqdEVDGLVSGAVhTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQ--- 547
Cdd:PRK07742 81 LAVKAVRNG------------------------EADVLMKGNV-PTANILKAVLNKEWGLRKGSVLSHVAVFEVPNYdrl 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 548 VYVyGDCAINPDPTAEQLAEIAIQSAESAIAFGIE-PRVAMLsystgtsGAGSDVEKVREAT----RLAQEKR----PDL 618
Cdd:PRK07742 136 IFV-TDAAMNIAPDLEQKAAIIQNAVEVARAIGIDlPKVAPL-------AAVEVVNPAMQATidaaALTQMNRrgqiKNC 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 619 MIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADlISIGPMLQGMRKPVNDLSRGALVDDI 698
Cdd:PRK07742 208 VVDGPLALDNAVSQIAAEHKGIVSDVAGKADILLVPTIEAGNVLYKSLVYFAD-AKVGAMIAGAKAPIVLTSRADSAETK 286
|
330
....*....|....
gi 581977824 699 VYTIALtAIQSSQQ 712
Cdd:PRK07742 287 LYSLAL-AVCTASK 299
|
|
| PRK05805 |
PRK05805 |
phosphate butyryltransferase; Validated |
412-712 |
1.63e-17 |
|
phosphate butyryltransferase; Validated
Pssm-ID: 180267 Cd Length: 301 Bit Score: 83.99 E-value: 1.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 412 DEP--RTVKAAAicaERGIATCVLLGNPEEINRVAASQGVELgAGIEIVDPEVVRES--YVARLVelrkSKGMTETVARe 487
Cdd:PRK05805 27 DEPvlEAVKEAK---ELGIANAILVGDKEKIKEIAKEIDMDL-EDFEIIDEKDNRKAalKAVELV----SSGKADMVMK- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 488 qlednvvlgtlmleqdevdGLVSgavhtTANTIRPPLQLIKTAPGSSLVSSVFFMLLP--EQVYVYGDCAINPDPTAEQL 565
Cdd:PRK05805 98 -------------------GLVD-----TANFLRAVLNKEIGLRTGKTMSHVAVFEVPkyDRLLFLTDAAFNIAPDLKEK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 566 AEIAIQSAESAIAFGIE-PRVAMLSystgtsgagsDVEKVR-------EATRLAQEKR----PDLMIDGPLQYDAAVMAD 633
Cdd:PRK05805 154 IDIINNAVTVAHAIGIEnPKVAPIC----------AVEVVNpkmpatlDAALLSKMSDrgqiKGCIVDGPLALDNALSEE 223
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581977824 634 VAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLiSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSSQQ 712
Cdd:PRK05805 224 AAKHKGIDGPVAGNADILLVPNIEAGNVMYKTLTYFADC-KNGGLLVGTSAPVVLTSRADSHETKLNSIALAALVAAKL 301
|
|
| PRK08190 |
PRK08190 |
bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated |
406-686 |
1.84e-16 |
|
bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated
Pssm-ID: 236180 [Multi-domain] Cd Length: 466 Bit Score: 82.62 E-value: 1.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 406 VVLPEgdEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELgAGIEIVDPEVVRESyVARLVELrkskgmtetvA 485
Cdd:PRK08190 181 VVHPC--DAESLRGALEAAEAGLIEPVLVGPEAKIRAAAEEAGLDL-SGVRIVDVPHSHAA-AARAVAL----------A 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 486 ReqlednvvlgtlmleQDEVDGLVSGAVHT---TANTIRPPLQLiKTApgsSLVSSVFFMLLP--EQVYVYGDCAINPDP 560
Cdd:PRK08190 247 R---------------AGEVEALMKGSLHTdelLSAVVARDSGL-RTE---RRISHVFAMDVPtyPRPLLITDAAINIAP 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 561 TAEQLAEIaIQSA-ESAIAFGIE-PRVAMLSystgtsgagsDVEKVREATR-----LAQEKRPDL------MIDGPLQYD 627
Cdd:PRK08190 308 TLEDKRDI-VQNAiDLAHALGVEePKVAILS----------AVETVNPKMPstldaAALCKMADRgqitggIVDGPLAFD 376
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 581977824 628 AAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLqGMRKPV 686
Cdd:PRK08190 377 NAISAEAARTKGIVSPVAGQADILVVPDLEAGNMLAKQLTYLAGADAAGIVL-GARVPI 434
|
|
| PRK11890 |
PRK11890 |
phosphate acetyltransferase; Provisional |
419-660 |
4.97e-13 |
|
phosphate acetyltransferase; Provisional
Pssm-ID: 183361 Cd Length: 312 Bit Score: 70.40 E-value: 4.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 419 AAAICAERGIATCVLLGNPEEINRVAASQGVELGaGIEIVDPEVVRESyVARLVELrkskgmtetvAREQlednvvlgtl 498
Cdd:PRK11890 38 GAVEAAQLGLITPILVGPRARIEAVAAECGLDLS-GYEIVDAPHSHAA-AAKAVEL----------VREG---------- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 499 mleqdEVDGLVSGAVHTTantirpplQLIK--TAPGSSL-----VSSVFFMLLP--EQVYVYGDCAINPDPTAEQLAEIA 569
Cdd:PRK11890 96 -----EAEALMKGSLHTD--------ELMSavVARDTGLrterrISHVFVMDVPgyPKPLIITDAAVNIAPTLEDKADIV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 570 IQSAESAIAFGI-EPRVAMLS-YSTGTSGAGSDVEkvreATRLAqeKRPD------LMIDGPLQYDAAVMADVAKSKAPN 641
Cdd:PRK11890 163 QNAIDLAHALGFdEPRVAILSaVETVNPKIPSTLD----AAALC--KMADrgqitgAILDGPLAFDNAISPEAARIKGIV 236
|
250
....*....|....*....
gi 581977824 642 SPVAGRATVFIFPDLNTGN 660
Cdd:PRK11890 237 SPVAGDADILVVPDLEAGN 255
|
|
| BioD |
COG0132 |
Dethiobiotin synthetase [Coenzyme transport and metabolism]; Dethiobiotin synthetase is part ... |
10-136 |
1.81e-06 |
|
Dethiobiotin synthetase [Coenzyme transport and metabolism]; Dethiobiotin synthetase is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 439902 [Multi-domain] Cd Length: 222 Bit Score: 49.39 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581977824 10 TGTSVGLTSVSLGVIRAMERKGVRLSVFKPIA---QPRAGGNAP-DqtTAIVRANSSVpaaePLKMSHVESL-------- 77
Cdd:COG0132 9 TDTDVGKTVVTAALAAALRAAGLRVGYYKPVQtgcEETDGGLRNgD--AELLRRLSGL----PLSYELVNPYrfeeplsp 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 581977824 78 -LSSNQ--KDVLMEEIIANYHANTKDAEVVLVEG----LVP-TRKHQFAqslnyEIAKTLNAEIVFV 136
Cdd:COG0132 83 hLAARLegVPIDLDKILAALRALAARYDLVLVEGagglLVPlTEDLTLA-----DLAKALGLPVILV 144
|
|
| |
