|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
1-432 |
0e+00 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 863.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 1 MKKLFVQFYLLLFVCFLVMTMLVGLVYKFTAERAGRQSLDDLMKSSLYLMRSELREIPPHDWAKTLKELDLNLSFDLRIE 80
Cdd:PRK10604 1 MRKLFIQFYLLLFVCFLVMTLLVGLVYKFTAERAGRQSLDDLMKSSLYLMRSELREIPPRDWGKTLKEMDLNLSFDLRIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 81 PLKDFDLDPPAMQRLRDGDIVALDEKYTFIQRIPRSHYVLAVGPVPYLYYLHQMRLLDMALMAFIAISLAFPVFIWMRPH 160
Cdd:PRK10604 81 PLSKYHLDPASQQRLREGEIVALDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALLALIGLSLAFPVFLWMRPH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 161 WQDMLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSENL 240
Cdd:PRK10604 161 WQDMLKLEAAAQRLGDGHLAERIHFDEGSSLERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDNL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 241 TEAESQALNRDIGQLEALIEELLTYARLDRPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTL-LTRVTPGDYGALDMRLM 319
Cdd:PRK10604 241 SAAESQALNRDIGQLEALIEELLTYARLDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVrLDTPHQGDYGALDMRLM 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 320 ERVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQA 399
Cdd:PRK10604 321 ERVLDNLLNNALRYAHSRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALA 400
|
410 420 430
....*....|....*....|....*....|...
gi 556496302 400 MGGTVHCEESELGGARFCFSWPVYHNIALPVPA 432
Cdd:PRK10604 401 MGGSVNCDESELGGARFSFSWPVWHNLPQFTSA 433
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-422 |
1.07e-55 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 179.55 E-value: 1.07e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQ 398
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVAL 80
|
90 100
....*....|....*....|....
gi 556496302 399 AMGGTVHCEESELGGARFCFSWPV 422
Cdd:cd16939 81 WHGGHVECDDSELGGACFRLTWPR 104
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
92-425 |
2.63e-53 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 182.83 E-value: 2.63e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 92 MQRLRDGDIVALDEKYTFIQRIPRSHYVLAVGPVPYLYYLHQMRLLDMALMAFIAISLAFPVFIWMRPHWQDMLKLESAA 171
Cdd:COG5002 45 LLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSEL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 172 QRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEM----SENLTEAESQA 247
Cdd:COG5002 125 LLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELlldgAADDPEERREY 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 248 LNR---DIGQLEALIEELLTYARLDRPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTLLTRVTPGDYGAL---DMRLMER 321
Cdd:COG5002 205 LEIileEAERLSRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLvlgDPDRLEQ 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 322 VLDNLMNNAMRYSE--STLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQA 399
Cdd:COG5002 285 VLTNLLDNAIKYTPegGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEA 364
|
330 340
....*....|....*....|....*.
gi 556496302 400 MGGTVHCEESELGGARFCFSWPVYHN 425
Cdd:COG5002 365 HGGRIWVESEPGKGTTFTITLPLARE 390
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
128-422 |
4.56e-53 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 180.49 E-value: 4.56e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 128 LYYLHQMRLLDMALMAFIAISLAFPVFIWMRPHWQDMLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINA 207
Cdd:COG0642 26 LLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 208 LIASKKQLIDGIAHELRTPLVRLRYRLEM-SENLTEAESQALN---RDIGQLEALIEELLTYARLDRPQNELNLSTPDLP 283
Cdd:COG0642 106 ANEAKSRFLANVSHELRTPLTAIRGYLELlLEELDEEQREYLEtilRSADRLLRLINDLLDLSRLEAGKLELEPEPVDLA 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 284 AWLQTHIDDVQSVNPQRTL-LTRVTPGDYGAL--DMRLMERVLDNLMNNAMRYSE--STLQIGLDLQGNQASLTVEDDGP 358
Cdd:COG0642 186 ELLEEVVELFRPLAEEKGIeLELDLPDDLPTVrgDPDRLRQVLLNLLSNAIKYTPegGTVTVSVRREGDRVRISVEDTGP 265
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556496302 359 GIAPEARETVFEPFVRLDPSrdRATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:COG0642 266 GIPPEDLERIFEPFFRTDPS--RRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPL 327
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
197-422 |
1.10e-52 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 176.25 E-value: 1.10e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 197 AFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEM---SENLTEAESQAL----NRDIGQLEALIEELLTYARLD 269
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELlldEEDLSPEERRELleiiRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 270 RPQNELNLSTPDLPAWLQTHIDDVQSVNPQR--TLLTRVTPGD-YGALDMRLMERVLDNLMNNAMRYS--ESTLQIGLDL 344
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEEKgiRLELDLPPELpLVYADPELLEQVLANLLDNAIKYSppGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556496302 345 QGNQASLTVEDDGPGIAPEARETVFEPFVRLDpsRDRATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYRGD--NSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPL 236
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
135-424 |
6.44e-41 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 151.24 E-value: 6.44e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 135 RLLDMALMAFIAISLA-FPVFIWMRphW---QDMLKLESAAQRFGEGHFTERIHFDSGSS-FERLGVAFNQMADNINALI 209
Cdd:PRK09470 163 LLFDRPLLLLLVTMLVsTPLLLWLA--WslaKPARKLKNAADEVAQGNLRQHPELETGPQeFRQAGASFNQMVTALERMM 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 210 ASKKQLIDGIAHELRTPLVRL-------RYRLEMSENLTEAESQALnrdigQLEALIEELLTyarLDRPQ--NELNLSTP 280
Cdd:PRK09470 241 TSQQRLLSDISHELRTPLTRLqlatallRRRQGESKELERIETEAQ-----RLDSMINDLLV---LSRNQqkNHLERETF 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 281 DLPAWLQTHIDDVQSVNPQR--TLLTRVTPGDYGAL-DMRLMERVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDG 357
Cdd:PRK09470 313 KANSLWSEVLEDAKFEAEQMgkSLTVSAPPGPWPINgNPNALASALENIVRNALRYSHTKIEVAFSVDKDGLTITVDDDG 392
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556496302 358 PGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPVYH 424
Cdd:PRK09470 393 PGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLPLYK 459
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
129-421 |
1.36e-39 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 147.67 E-value: 1.36e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 129 YYLHQMR--LLDMALMAFIAISLAFPVFIWMRphwQDMLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNIN 206
Cdd:NF012163 158 FDSQQKRasWLIVALALLLAALAAFLLARGLL---APVKRLVEATHRLAAGDYTTRVTPTSNDELGKLAQDFNQLASTLE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 207 ALIASKKQLIDGIAHELRTPLVRLRYRLEMSEN----LTEAESQALNRDIGQLEALIEELLTYARLDRPQNELNLSTPDL 282
Cdd:NF012163 235 KNEQMRRDFMADISHELRTPLAVLRAELEAIQDgirkFTPESLDSLQAEVGTLTKLVDDLHDLSMSDEGALAYQKASVDL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 283 PAWLQTHIDDVQSVNPQRTLLTRV----TPGDYGALDmRLMErVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDD 356
Cdd:NF012163 315 VPLLEVEGGAFRERFASAGLELEVslpdSSLVFGDRD-RLMQ-LFNNLLENSLRYTDSggSLHISASQRPKEVTLTVADS 392
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556496302 357 GPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWP 421
Cdd:NF012163 393 APGVSDEQLARLFERFYRVEVSRNRASGGSGLGLAISLNIVQAHGGTLHAAHSPLGGLRIVVTLP 457
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
137-418 |
3.17e-38 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 143.51 E-value: 3.17e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 137 LDMALMAFIAISLAFpvfIWMRPHWQD--MLKLESAAQRFGEGHFTERIHfDSGSSfERLGV--AFNQMADNINALIASK 212
Cdd:PRK09467 155 LFRYTLAIGLLSVAG---GWLFIRIQNrpLVALEHAALQVGKGEIPPPLR-EYGAS-EVRSVtrAFNQMAAGIKQLEDDR 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 213 KQLIDGIAHELRTPLVRLRYRLEM--SENLTEAESqaLNRDIGQLEALIEELLTYARLDrpqNELNLSTPDLPAWLQthi 290
Cdd:PRK09467 230 TLLMAGVSHDLRTPLTRIRLATEMmsEEDGYLAES--INKDIEECNAIIEQFIDYLRTG---QEMPMEMADLNALLG--- 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 291 DDVQSVNP-QRTLLTRVTPGDYGALDMRL-MERVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETV 368
Cdd:PRK09467 302 EVIAAESGyEREIETALQPGPIEVPMNPIaIKRALANLVVNAARYGNGWIKVSSGTEGKRAWFQVEDDGPGIPPEQLKHL 381
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 556496302 369 FEPFVRLDpsRDRATGGCGLGLAIVHSIAQAMGGTVHCEESELGG--ARFCF 418
Cdd:PRK09467 382 FQPFTRGD--SARGSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGlsARAWL 431
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
315-422 |
3.40e-33 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 120.83 E-value: 3.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPsRDRATGGCGLGLAI 392
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPEggRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDK-RSRKIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|
gi 556496302 393 VHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
147-422 |
8.50e-33 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 128.16 E-value: 8.50e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 147 ISLAFPVFIWMRPHWQDMLKLESAAQRfgeghfTERIHfdsGSSFERLG--VAFnqmaDNINALIASKK-----QLIDGI 219
Cdd:COG5000 142 LDLAELLREALERGWQEEIELTRDGRR------TLLVR---ASPLRDDGyvIVF----DDITELLRAERlaawgELARRI 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 220 AHELRTPL---------VRLRYRLEMSENLTEAES--QALNRDIGQLEALIEELLTYARLDRPQNELNlstpDLPAWLQ- 287
Cdd:COG5000 209 AHEIKNPLtpiqlsaerLRRKLADKLEEDREDLERalDTIIRQVDRLKRIVDEFLDFARLPEPQLEPV----DLNELLRe 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 288 -THIDDVQSVNPQRTLLTRVTPGD-YGALDMRLMERVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPE 363
Cdd:COG5000 285 vLALYEPALKEKDIRLELDLDPDLpEVLADRDQLEQVLINLLKNAIEAIEEggEIEVSTRREDGRVRIEVSDNGPGIPEE 364
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556496302 364 ARETVFEPFVrldpsrdraT---GGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:COG5000 365 VLERIFEPFF---------TtkpKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPL 417
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
170-403 |
1.98e-32 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 128.60 E-value: 1.98e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 170 AAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIAS-------KKQLIDGIAHELRTPLVRLRyrleMSENL-- 240
Cdd:NF040691 222 TAERFAAGDLSERMPVKGEDDLARLARSFNQMADSLQRQIRQleelsrlQQRFVSDVSHELRTPLTTIR----MAADVih 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 241 ---------TEAESQALNRDIGQLEALIEELLTYARLDRPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTLLTRV-TPGD 310
Cdd:NF040691 298 dsrddfdpaTARSAELLHTELDRFESLLSDLLEISRFDAGAAELDVEPVDLRPLVRRVVDALRQLAERAGVELRVdAPGT 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 311 YGALDM--RLMERVLDNLMNNAMRYSEST-LQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCG 387
Cdd:NF040691 378 PVVAEVdpRRVERVLRNLVVNAIEHGEGKpVVVTVAQDDTAVAVTVRDHGVGLKPGEVALVFDRFWRADPARARTTGGTG 457
|
250
....*....|....*.
gi 556496302 388 LGLAIVHSIAQAMGGT 403
Cdd:NF040691 458 LGLAIALEDARLHGGW 473
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
166-426 |
8.23e-31 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 123.20 E-value: 8.23e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 166 KLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSEN----LT 241
Cdd:PRK10549 194 RLVEGTHKLAAGDFTTRVTPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRTPLAVLRGELEAIQDgvrkFT 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 242 EAESQALNRDIGQLEALIEELltyarldrpqNELNLSTPDLPAWLQTHIDDVQSV------------NPQRTLLTRVTP- 308
Cdd:PRK10549 274 PESVASLQAEVGTLTKLVDDL----------HQLSLSDEGALAYRKTPVDLVPLLevaggafrerfaSRGLTLQLSLPDs 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 309 ----GDYGaldmRLMErVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRA 382
Cdd:PRK10549 344 atvfGDPD----RLMQ-LFNNLLENSLRYTDSggSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRA 418
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 556496302 383 TGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPVYHNI 426
Cdd:PRK10549 419 SGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDL 462
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
219-422 |
1.39e-30 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 123.36 E-value: 1.39e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 219 IAHELRTPLVRLRY---RLEM--SENLTEAESQALNR---DIGQLEALIEELLTYARLDRpqNELNLSTPDLPAWLQTHI 290
Cdd:COG4251 289 ASHDLREPLRKISGfsqLLEEdyGDKLDEEGREYLERirdAAERMQALIDDLLAYSRVGR--QELEFEPVDLNELLEEVL 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 291 DDVQSVNPQRTllTRVTPGDYGAL--DMRLMERVLDNLMNNAMRYSES----TLQIGLDLQGNQASLTVEDDGPGIAPEA 364
Cdd:COG4251 367 EDLEPRIEERG--AEIEVGPLPTVrgDPTLLRQVFQNLISNAIKYSRPgeppRIEIGAEREGGEWVFSVRDNGIGIDPEY 444
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 556496302 365 RETVFEPFVRLDPSRDRatGGCGLGLAIVHSIAQAMGGTVHCEeSELG-GARFCFSWPV 422
Cdd:COG4251 445 AEKIFEIFQRLHSRDEY--EGTGIGLAIVKKIVERHGGRIWVE-SEPGeGATFYFTLPK 500
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
197-421 |
3.54e-30 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 121.34 E-value: 3.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 197 AFNQMADNINALIASKKQLIDGIAHELRTPLVRL---------------RYRLEMSENLTEaesqaLNRdigqLEALIEE 261
Cdd:TIGR01386 226 SFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLlgqtqvalsqprtgeEYREVLESNLEE-----LER----LSRMVSD 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 262 LLTYARLDRPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTLLTRVTPGDYGALDMRLMERVLDNLMNNAMRYS--ESTLQ 339
Cdd:TIGR01386 297 MLFLARADNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEGLVRGDPQMFRRAISNLLSNALRHTpdGGTIT 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 340 IGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGGTVHCeESELGGARFCFS 419
Cdd:TIGR01386 377 VRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRASA-ESPDGKTRFILR 455
|
..
gi 556496302 420 WP 421
Cdd:TIGR01386 456 FP 457
|
|
| AdeS_HK |
NF012226 |
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component ... |
167-419 |
1.07e-29 |
|
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component regulatory system for the AdeABC efflux pump can confer adaptive resistance to certain antibiotics, including tigecycline.
Pssm-ID: 411090 [Multi-domain] Cd Length: 353 Bit Score: 118.17 E-value: 1.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 167 LESAAQRFGEGHFTERIHFDSGSSFE--RLGVAFNQMADNI-----NALIASKkqlidGIAHELRTPLVRLRYRLE-MSE 238
Cdd:NF012226 91 LADAAKKISQGDLSARAEDSQIHSAEisELMHNFNDMAQKLessvkNAQVWNA-----AIAHELRTPITILQGRLQgILD 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 239 NLTEAEsQALNRD-IGQLEA---LIEELLTYARLDRPQNELNLSTPDlpawLQTHIDDVQSVNPQRTLLTRVTP-----G 309
Cdd:NF012226 166 GVFEPD-PALFKSlLNQVEGlshLVEDLRTLSLVENQQLRLNYESVD----LKDSIEKVLKMFEDRLEQAQLTIvlnltA 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 310 DYGALDMRLMERVLDNLMNNAMRYSES-TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGL 388
Cdd:NF012226 241 TPVFCDRRRIEQVLIALIDNAIRYANAgKLKISSSVIQDDWILQIEDEGPGIAEEYQQDLFNPFFRLEQSRNKEFGGTGL 320
|
250 260 270
....*....|....*....|....*....|.
gi 556496302 389 GLAIVHSIAQAMGGTVHCEESelgGARFCFS 419
Cdd:NF012226 321 GLAVVHAIVIAHKGSIEYSNS---QGNSVFT 348
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-421 |
5.22e-29 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 109.34 E-value: 5.22e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQ 398
Cdd:cd16949 1 LARALENVLRNALRYSPSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERAIE 80
|
90 100
....*....|....*....|...
gi 556496302 399 AMGGTVHCEESELGGARFCFSWP 421
Cdd:cd16949 81 QHGGKIKASNRKPGGLRVRIWLP 103
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
91-422 |
1.70e-28 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 115.28 E-value: 1.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 91 AMQRLRDGDIVALDEKYTFIQRIPRSHYVLAVGPVPYLYYLHQMRLLDMALMAFIAISLAFPVFI---WMRPHWQDMLKL 167
Cdd:COG4191 6 LLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLAllgGLLRLLLLLGLL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 168 ESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIASKKQLID------------GIAHELRTPLVRLRYRLE 235
Cdd:COG4191 86 LLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQseklaalgelaaGIAHEINNPLAAILGNAE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 236 MSENLTEAE------SQALNRDIGQLE---ALIEELLTYARLDRPQNE-----------LNLSTPDLPA---WLQTHID- 291
Cdd:COG4191 166 LLRRRLEDEpdpeelREALERILEGAEraaEIVRSLRAFSRRDEEEREpvdlnelideaLELLRPRLKArgiEVELDLPp 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 292 DVQSVNpqrtlltrvtpGDYGALdmrlmERVLDNLMNNAM----RYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARET 367
Cdd:COG4191 246 DLPPVL-----------GDPGQL-----EQVLLNLLINAIdameEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLER 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 556496302 368 VFEPFVrldpSRDRATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:COG4191 310 IFEPFF----TTKPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPL 360
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
315-422 |
4.40e-27 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 104.37 E-value: 4.40e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYS--ESTLQIGLDlQGNQASLTVEDDGPGIAPEARETVFEPFVRLDpsrDRATGGCGLGLAI 392
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAakAGEITVTLS-EGGELTLTVEDNGIGIPPEDLPRIFEPFSTAD---KRGGGGTGLGLSI 77
|
90 100 110
....*....|....*....|....*....|
gi 556496302 393 VHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:pfam02518 78 VRKLVELLGGTITVESEPGGGTTVTLTLPL 107
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
219-418 |
4.48e-27 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 110.38 E-value: 4.48e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 219 IAHELRTPLVRLRYRLEMSENLTEAESQALNRDIGQ-------LEALIEELLTYARLDRPQNELNLSTPDLPAWLQTHID 291
Cdd:TIGR02966 121 VSHELRTPLTVLRGYLETLADGPDEDPEEWNRALEImleqsqrMQSLVEDLLTLSRLESAASPLEDEPVDMPALLDHLRD 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 292 DVQSVNPQR----TLLTRVTPGDYGALDmRLMErVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPEAR 365
Cdd:TIGR02966 201 EAEALSQGKnhqiTFEIDGGVDVLGDED-ELRS-AFSNLVSNAIKYTPEggTITVRWRRDGGGAEFSVTDTGIGIAPEHL 278
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 556496302 366 ETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCF 418
Cdd:TIGR02966 279 PRLTERFYRVDKSRSRDTGGTGLGLAIVKHVLSRHHARLEI-ESELGkGSTFSF 331
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
315-421 |
4.70e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 104.08 E-value: 4.70e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAI 392
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTggKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 556496302 393 VHSIAQAMGGTVHCEESELGGARFCFSWP 421
Cdd:cd16946 81 CHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
213-424 |
3.87e-25 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 105.70 E-value: 3.87e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 213 KQLIDGIAHELRTPLVRLRYRLE-MSENLTEAESQALNRDIGQ----LEALIEELLTYARLDRPQnelnLSTPDLPAWLQ 287
Cdd:COG3852 136 GELAAGLAHEIRNPLTGIRGAAQlLERELPDDELREYTQLIIEeadrLNNLVDRLLSFSRPRPPE----REPVNLHEVLE 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 288 THIDDVQSVNPQRTLLTRvtpgDYGA------LDMRLMERVLDNLMNNAMR------------YSESTLQIGLDLQGNQA 349
Cdd:COG3852 212 RVLELLRAEAPKNIRIVR----DYDPslpevlGDPDQLIQVLLNLVRNAAEampeggtitirtRVERQVTLGGLRPRLYV 287
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556496302 350 SLTVEDDGPGIAPEARETVFEPFVRldpSRDRATggcGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWPVYH 424
Cdd:COG3852 288 RIEVIDNGPGIPEEILDRIFEPFFT---TKEKGT---GLGLAIVQKIVEQHGGTIEV-ESEPGkGTTFRIYLPLEQ 356
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
322-422 |
7.65e-25 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 97.95 E-value: 7.65e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 322 VLDNLMNNAMRYSES---TLQI---GLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHS 395
Cdd:cd16922 4 ILLNLLGNAIKFTEEgevTLRVsleEEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAISKK 83
|
90 100
....*....|....*....|....*...
gi 556496302 396 IAQAMGGTVHCeESELG-GARFCFSWPV 422
Cdd:cd16922 84 LVELMGGDISV-ESEPGqGSTFTFTLPL 110
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-417 |
5.40e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 95.59 E-value: 5.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDraTGGCGLGLAIVHSIAQ 398
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARG--TSGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|.
gi 556496302 399 AMGGTVHCEESELGG--ARFC 417
Cdd:cd16950 79 AHGGSLTLANRAGGGlcARIE 99
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
197-398 |
1.32e-23 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 101.20 E-value: 1.32e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 197 AFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSENLTEAESQALNRDIGQLEALIEELLTYARLDRP----- 271
Cdd:PRK10755 122 ALNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHHIDVAPLIARLDQMMHTVEQLLQLARAGQSfssgh 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 272 QNELNLsTPDLPAWLQTHIDDVQSVNPQRTLLTRVT-----PGDygALDMRLMERvldNLMNNAMRYS--ESTLQIGLDL 344
Cdd:PRK10755 202 YQTVKL-LEDVILPSQDELSEMLEQRQQTLLLPESAaditvQGD--ATLLRLLLR---NLVENAHRYSpeGSTITIKLSQ 275
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 556496302 345 QGNQASLTVEDDGPGIAPEARETVFEPFVRLdpsrDRATGGCGLGLAIVHSIAQ 398
Cdd:PRK10755 276 EDGGAVLAVEDEGPGIDESKCGELSKAFVRM----DSRYGGIGLGLSIVSRITQ 325
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
114-421 |
9.65e-23 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 100.23 E-value: 9.65e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 114 PRSHYVLAVGPVP--YLYYLHQMRLLDMALMAFIAISLAFPVFIWMRPHWQDMLKLESAAQRFGEGHFTERIHFDSGS-S 190
Cdd:PRK09835 161 GKPIYTLLIALSIdfHLHYINDLKNKLIMTASVISLLIVFIVLLAVHKGHAPIRSVSRQIQNITSKDLDVRLDPQTVPiE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 191 FERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSenLTEAESQALNRDI--------GQLEALIEEL 262
Cdd:PRK09835 241 LEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIA--LSQSRSQKELEDVlysnleelTRMAKMVSDM 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 263 LTYARLDRPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTLLTRVTpGDYGAL--DMRLMERVLDNLMNNAMRYSES--TL 338
Cdd:PRK09835 319 LFLAQADNNQLIPEKKMLDLADEVGKVFDFFEAWAEERGVELRFV-GDPCQVagDPLMLRRAISNLLSNALRYTPAgeAI 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 339 QIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGGTVHCeESELGGARFCF 418
Cdd:PRK09835 398 TVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAV-TSDARGTRFVI 476
|
...
gi 556496302 419 SWP 421
Cdd:PRK09835 477 SLP 479
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-416 |
1.12e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 93.08 E-value: 1.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 308 PGDYGALdmrlMErVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDratgGCG 387
Cdd:cd16954 32 PGERNDL----ME-LLGNLLDNACKWCLEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQRP----GQG 102
|
90 100
....*....|....*....|....*....
gi 556496302 388 LGLAIVHSIAQAMGGTVHCEESELGGARF 416
Cdd:cd16954 103 LGLAIAKEIVEQYGGELSLSDSPLGGARF 131
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
219-422 |
6.25e-21 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 95.48 E-value: 6.25e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 219 IAHELRTPLVRLRYRLEMSENLTEAESQALNRDIGQ-----LEALIEELLTYARLDRPQNELNL-STPDLP----AWLQT 288
Cdd:PRK15347 405 ISHEIRTPLNGVLGALELLQNTPLTAEQMDLADTARqctlsLLAIINNLLDFSRIESGQMTLSLeETALLPlldqAMLTI 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 289 HiddVQSVNPQRTLLTRVTPG--DYGALD-MRLmERVLDNLMNNAMRYSES-TLQIGLDLQGNQASLTVEDDGPGIAPEA 364
Cdd:PRK15347 485 Q---GPAQSKSLTLRTFVGAHvpLYLHLDsLRL-RQILVNLLGNAVKFTETgGIRLRVKRHEQQLCFTVEDTGCGIDIQQ 560
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 556496302 365 RETVFEPFVRLDPSrdraTGGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWPV 422
Cdd:PRK15347 561 QQQIFTPFYQADTH----SQGTGLGLTIASSLAKMMGGELTL-FSTPGvGSCFSLVLPL 614
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
219-421 |
1.21e-20 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 93.54 E-value: 1.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 219 IAHELRTPLVRLRYRLEMSENlTEAESQALNRDIG-------QLEALIEELLTYARLD-RPQNELNlSTPDLPAWLQTHI 290
Cdd:PRK11006 211 VSHELRTPLTVLQGYLEMMQD-QPLEGALREKALHtmreqtqRMEGLVKQLLTLSKIEaAPTIDLN-EKVDVPMMLRVLE 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 291 DDVQSV-NPQRTLLTRVTPG--DYGALDMrlMERVLDNLMNNAMRYSESTLQIGLDLQGNQ--ASLTVEDDGPGIAPEAR 365
Cdd:PRK11006 289 REAQTLsQGKHTITFEVDNSlkVFGNEDQ--LRSAISNLVYNAVNHTPEGTHITVRWQRVPqgAEFSVEDNGPGIAPEHI 366
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 556496302 366 ETVFEPFVRLDPSRDRATGGCGLGLAIV-HSIAQAmggTVHCE-ESELG-GARFCFSWP 421
Cdd:PRK11006 367 PRLTERFYRVDKARSRQTGGSGLGLAIVkHALSHH---DSRLEiESEVGkGTRFSFVLP 422
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
315-421 |
2.74e-20 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 85.62 E-value: 2.74e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYSESTLQIGLDLQ---GNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLA 391
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEkfrLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 556496302 392 IVHSIAQAMGGTVHCEESELGGARFCFSWP 421
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
181-422 |
3.71e-20 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 93.18 E-value: 3.71e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 181 ERIHFDSGSSFERLGVAFNQMAdniNALIASkkqlidgIAHELRTPLVRLRYRLEM------SENLTEAEsQA--LNRDI 252
Cdd:PRK10490 643 ERLTLTASEEQARLASEREQLR---NALLAA-------LSHDLRTPLTVLFGQAEIltldlaSEGSPHAR-QAseIRQQV 711
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 253 GQLEALIEELLTYARLDRPQNELNLSTPDL------------PAWLQTHIddvqSVN-PQRTLLTRVtpgdygalDMRLM 319
Cdd:PRK10490 712 LNTTRLVNNLLDMARIQSGGFNLRKEWLTLeevvgsalqmlePGLSGHPI----NLSlPEPLTLIHV--------DGPLF 779
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 320 ERVLDNLMNNAMRYSESTLQIGLD--LQGNQASLTVEDDGPGIAPEARETVFEPFVRLDpsRDRATGGCGLGLAIVHSIA 397
Cdd:PRK10490 780 ERVLINLLENAVKYAGAQAEIGIDahVEGERLQLDVWDNGPGIPPGQEQLIFDKFARGN--KESAIPGVGLGLAICRAIV 857
|
250 260
....*....|....*....|....*
gi 556496302 398 QAMGGTVHCEESELGGARFCFSWPV 422
Cdd:PRK10490 858 EVHGGTIWAENRPEGGACFRVTLPL 882
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
197-420 |
3.72e-20 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 92.02 E-value: 3.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 197 AFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSEnLTEAESQALNRDIGQLEA-------LIEELLTYARLD 269
Cdd:PRK10337 222 ALNQLFARTHAMMVRERRFTSDAAHELRSPLAALKVQTEVAQ-LSDDDPQARKKALLQLHAgidratrLVDQLLTLSRLD 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 270 RPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTLLTRVTPGDYG------ALDMRLMERvldNLMNNAMRYSESTLQIGLD 343
Cdd:PRK10337 301 SLDNLQDVAEIPLEDLLQSAVMDIYHTAQQAGIDVRLTLNAHPvirtgqPLLLSLLVR---NLLDNAIRYSPQGSVVDVT 377
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556496302 344 LqgNQASLTVEDDGPGIAPEARETVFEPFVRldPSRDRATGGcGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSW 420
Cdd:PRK10337 378 L--NARNFTVRDNGPGVTPEALARIGERFYR--PPGQEATGS-GLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVSW 449
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
133-422 |
4.45e-20 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 92.21 E-value: 4.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 133 QMRLLDMALMAFIAISLAFPVFIW--MRPhwqdMLKLESAAQRFGEGhftERIHFD--SGSSFERLGVAFNQMADNINAl 208
Cdd:PRK11100 181 ERRILWAGALLLGIALLIGAGVVWwlNRS----IRRLTRYADAVTEG---KPVPLPklGSSELRELAQALESMRVKLEG- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 209 iaskKQLIDG----IAHELRTPLVRLRYRLE-MSENLTEAESQALNRDI----GQLEALIEELLTYARLDRPQNELNLST 279
Cdd:PRK11100 253 ----KAYVEQyvqtLTHELKSPLAAIRGAAElLQEDPPPEDRARFTGNIltqsARLQQLIDRLLELARLEQRQELEVLEP 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 280 PDLPAWLQTHIDDVQSVNPQRTLLTRVTPGDYGAL-DMRLMERVLDNLMNNAMRYS--ESTLQIGLDLQGNQASLTVEDD 356
Cdd:PRK11100 329 VALAALLEELVEAREAQAAAKGITLRLRPDDARVLgDPFLLRQALGNLLDNAIDFSpeGGTITLSAEVDGEQVALSVEDQ 408
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556496302 357 GPGIAPEARETVFEPFVRLdPSRDRATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:PRK11100 409 GPGIPDYALPRIFERFYSL-PRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
318-420 |
3.01e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 82.84 E-value: 3.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 318 LMERVLDNLMNNAMRYSESTLQIGLDLQG-NQASLTVEDDGPGIAPEARETVFEPFVRLDPsrdRATGGCGLGLAIVHSI 396
Cdd:cd16940 13 LLFLLLRNLVDNAVRYSPQGSRVEIKLSAdDGAVIRVEDNGPGIDEEELEALFERFYRSDG---QNYGGSGLGLSIVKRI 89
|
90 100
....*....|....*....|....
gi 556496302 397 AQAMGGTVHCEESELGGARFCFSW 420
Cdd:cd16940 90 VELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
209-423 |
6.19e-19 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 87.70 E-value: 6.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 209 IASKKQLIDGIAHELRTPL---------VRLRYRLEMSENLTEAESQALNRDIGQL---EALIEELLTYARLDRPQNELN 276
Cdd:PRK09303 148 LKFKDRVLAMLAHDLRTPLtaaslaletLELGQIDEDTELKPALIEQLQDQARRQLeeiERLITDLLEVGRTRWEALRFN 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 277 LSTPDLPAWLQTHIDDVQS--VNPQRTLLTRVtPGD----YGalDMRLMERVLDNLMNNAMRYSESTLQIGLDL-----Q 345
Cdd:PRK09303 228 PQKLDLGSLCQEVILELEKrwLAKSLEIQTDI-PSDlpsvYA--DQERIRQVLLNLLDNAIKYTPEGGTITLSMlhrttQ 304
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556496302 346 GNQASltVEDDGPGIAPEARETVFEPFVRLDpsRDRATGGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWPVY 423
Cdd:PRK09303 305 KVQVS--ICDTGPGIPEEEQERIFEDRVRLP--RDEGTEGYGIGLSVCRRIVRVHYGQIWV-DSEPGqGSCFHFTLPVY 378
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-407 |
1.01e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 78.20 E-value: 1.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAMRYS--ESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDraTGGCGLGLAIVHSI 396
Cdd:cd16923 1 LQRVFSNLLSNAIKYSpeNTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRN--TEGAGLGLSIAKAI 78
|
90
....*....|.
gi 556496302 397 AQAMGGTVHCE 407
Cdd:cd16923 79 IELHGGSASAE 89
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
210-422 |
1.43e-17 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 85.02 E-value: 1.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 210 ASKKQLIDGIAHELRTPLVRLR-----YRLEMSENLTEAESQALNRDIGQLEALIEELLTYARLDRPQN---ELNLSTPD 281
Cdd:PRK11360 388 AALGELVAGVAHEIRNPLTAIRgyvqiWRQQTSDPPSQEYLSVVLREVDRLNKVIDQLLEFSRPRESQWqpvSLNALVEE 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 282 LPAWLQT--HIDDVQ-SVNPQRTLLTRVtpgdygaLDMRLMERVLDNLMNNAMRY--SESTLQIGLDLQGN-QASLTVED 355
Cdd:PRK11360 468 VLQLFQTagVQARVDfETELDNELPPIW-------ADPELLKQVLLNILINAVQAisARGKIRIRTWQYSDgQVAVSIED 540
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556496302 356 DGPGIAPEARETVFEPFVRLDPSrdratgGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWPV 422
Cdd:PRK11360 541 NGCGIDPELLKKIFDPFFTTKAK------GTGLGLALSQRIINAHGGDIEV-ESEPGvGTTFTLYLPI 601
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-418 |
2.38e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 77.11 E-value: 2.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAM----RYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPsrdrATGGCGLGLAIVH 394
Cdd:cd16976 1 IQQVLMNLLQNALdamgKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKP----VGKGTGLGLSISY 76
|
90 100
....*....|....*....|....
gi 556496302 395 SIAQAMGGTVHCEESELGGARFCF 418
Cdd:cd16976 77 GIVEEHGGRLSVANEEGAGARFTF 100
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
311-407 |
1.40e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 75.63 E-value: 1.40e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 311 YGALDMRLMERVLDNLMNNAMRYSESTLQIGLDLQGNQAS--LTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGL 388
Cdd:cd16947 13 YANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHvyIDIWDKGKGISETEKDHVFERLYTLEDSRNSAKQGNGL 92
|
90
....*....|....*....
gi 556496302 389 GLAIVHSIAQAMGGTVHCE 407
Cdd:cd16947 93 GLTITKRLAESMGGSIYVN 111
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-421 |
5.21e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 73.20 E-value: 5.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNN---AMRYSEST---LQIGLDLQGNQA-SLTVEDDGPGIAPEARETVFEPFVRLDPSrdratgGCGLGLA 391
Cdd:cd16920 1 IQQVLINLVRNgieAMSEGGCErreLTIRTSPADDRAvTISVKDTGPGIAEEVAGQLFDPFYTTKSE------GLGMGLS 74
|
90 100 110
....*....|....*....|....*....|
gi 556496302 392 IVHSIAQAMGGTVHCEESELGGARFCFSWP 421
Cdd:cd16920 75 ICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-421 |
1.16e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 72.36 E-value: 1.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAMRYSEST----LQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPsrDRATGGCGLGLAIVH 394
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRrpprIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHS--REEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 556496302 395 SIAQAMGGTVHCEESELGGARFCFSWP 421
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
211-431 |
1.90e-15 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 78.79 E-value: 1.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 211 SKKQLIDGIAHELRTPL------VRLRYRLEMSENlTEAESQALNRDIGQLEALIEELLTYARLDRPQNELNLS-TPDLP 283
Cdd:PRK11466 443 AKSAFLAAMSHEIRTPLygilgtAQLLADNPALNA-QRDDLRAITDSGESLLTILNDILDYSAIEAGGKNVSVSdEPFEP 521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 284 AWLQTHIDDVQSVNPQRTLLTRVTpgDYGAL-------DMRLMERVLDNLMNNAMRYSES---TLQIGLDlqGNQASLTV 353
Cdd:PRK11466 522 RPLLESTLQLMSGRVKGRPIRLAT--DIADDlptalmgDPRRIRQVITNLLSNALRFTDEgsiVLRSRTD--GEQWLVEV 597
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556496302 354 EDDGPGIAPEARETVFEPFVRLDPSRdratGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPVYHnIALPVP 431
Cdd:PRK11466 598 EDSGCGIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRV-ATAPVP 670
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
314-417 |
8.13e-15 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 75.66 E-value: 8.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 314 LDMRLMERVLDNLMNNAMRYSES------TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRatggcG 387
Cdd:COG3290 277 LSDTDLVTILGNLLDNAIEAVEKlpeeerRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTKLGEGR-----G 351
|
90 100 110
....*....|....*....|....*....|
gi 556496302 388 LGLAIVHSIAQAMGGTVHCEESELGGARFC 417
Cdd:COG3290 352 LGLALVKQIVEKYGGTIEVESEEGEGTVFT 381
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-421 |
5.90e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 67.61 E-value: 5.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 325 NLMNNAMRYS--ESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGG 402
Cdd:cd16952 7 NLVSNAVKYTppSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHVMSRHDA 86
|
90 100
....*....|....*....|
gi 556496302 403 TVHCeESELG-GARFCFSWP 421
Cdd:cd16952 87 RLLI-ASELGkGSRFTCLFP 105
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
321-421 |
1.30e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 66.83 E-value: 1.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 321 RVLDNLMNNAMRYS-ESTLQIGLDL--QGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLGLAIVHSIA 397
Cdd:cd16953 3 QVLRNLIGNAISFSpPDTGRITVSAmpTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISRQII 82
|
90 100
....*....|....*....|....*...
gi 556496302 398 QAMGGTVHCEESE----LGGARFCFSWP 421
Cdd:cd16953 83 EAHGGISVAENHNqpgqVIGARFTVQLP 110
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-421 |
1.46e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 66.66 E-value: 1.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 319 MERVLDNLMNNAMRYSESTL-----------QIGLDLQGNQASLTVE--DDGPGIAPEARETVFEPFVrldPSRDratGG 385
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGgeiilrtrtqrQVTLGHPRHRLALRVSviDNGPGIPPDLQDTIFYPMV---SGRE---NG 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 556496302 386 CGLGLAIVHSIAQAMGGTVHCeESELGGARFCFSWP 421
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIEC-DSQPGHTVFSVSLP 109
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
214-422 |
3.78e-13 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 70.92 E-value: 3.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 214 QLIDGIAHELRTPLVRLRYRLE-MSENLTEAES--QALNRDIGQLEALIEELLTYARLDRPQNE-LNLST--PDLPAWLQ 287
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKGFLQlLQPGIEDKEEyfDIMLSELDRIESIISEFLALAKPQAVNKEkENINEliQDVVTLLE 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 288 TH--IDDVQSvnpqRTLLTRVTPGDYGalDMRLMERVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPE 363
Cdd:COG5805 369 TEaiLHNIQI----RLELLDEDPFIYC--DENQIKQVFINLIKNAIEAMPNggTITIHTEEEDNSVIIRVIDEGIGIPEE 442
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 556496302 364 ARETVFEPFVRLDPSrdratgGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:COG5805 443 RLKKLGEPFFTTKEK------GTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
318-422 |
7.67e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 64.37 E-value: 7.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 318 LMERVLDNLMNNAM----RYSESTLQIGLDLQgnQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDratgGCGLGLAIV 393
Cdd:cd16943 3 QLNQVLLNLLVNAAqameGRGRITIRTWAHVD--QVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGE----GTGLGLSLS 76
|
90 100 110
....*....|....*....|....*....|
gi 556496302 394 HSIAQAMGGTVHCeESELG-GARFCFSWPV 422
Cdd:cd16943 77 YRIIQKHGGTIRV-ASVPGgGTRFTIILPI 105
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
318-417 |
1.15e-12 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 69.28 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 318 LMErVLDNLMNNAMRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDratgGCGLGLAIVHSIA 397
Cdd:PRK10815 379 FME-VMGNVLDNACKYCLEFVEISARQTDEHLHIVVEDDGPGIPESKRELIFDRGQRADTLRP----GQGLGLSVAREIT 453
|
90 100
....*....|....*....|
gi 556496302 398 QAMGGTVHCEESELGGARFC 417
Cdd:PRK10815 454 EQYEGKISAGDSPLGGARME 473
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
215-422 |
1.27e-12 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 69.04 E-value: 1.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 215 LIDGIAHELRTPLVRL----RYRLEMSENLTEAE--SQALNRDIGQLEALIEELLtyaRLDRPqNELNLSTPDLPAWLQT 288
Cdd:PRK10364 240 LAAGVAHEIRNPLSSIkglaKYFAERAPAGGEAHqlAQVMAKEADRLNRVVSELL---ELVKP-THLALQAVDLNDLINH 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 289 HIDDVQSVNPQRTLLTRVTPGDY---GALDMRLMERVLDNLMNNAMRY--SESTLQIGLDLQGNQASLTVEDDGPGIAPE 363
Cdd:PRK10364 316 SLQLVSQDANSREIQLRFTANDTlpeIQADPDRLTQVLLNLYLNAIQAigQHGVISVTASESGAGVKISVTDSGKGIAAD 395
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 556496302 364 ARETVFEPFVRLDPSrdratgGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:PRK10364 396 QLEAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPV 448
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
315-415 |
3.30e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 62.94 E-value: 3.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYSEST----LQIGLDLQGNQA---SLTVEDDGPGIAPEARETVFEPFVRLDPSrdratgGCG 387
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRpsdvGEVRIRVEADQDgriVLIVCDNGKGFPREMRHRATEPYVTTRPK------GTG 74
|
90 100
....*....|....*....|....*...
gi 556496302 388 LGLAIVHSIAQAMGGTVHCEESELGGAR 415
Cdd:cd16944 75 LGLAIVKKIMEEHGGRISLSNREAGGAC 102
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-416 |
3.76e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 62.30 E-value: 3.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 322 VLDNLMNNA------MRYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRatggcGLGLAIVHS 395
Cdd:cd16915 4 IVGNLIDNAldalaaTGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGER-----GIGLALVRQ 78
|
90 100
....*....|....*....|.
gi 556496302 396 IAQAMGGTVHCEESELGGARF 416
Cdd:cd16915 79 SVERLGGSITVESEPGGGTTF 99
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
217-422 |
4.12e-12 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 65.80 E-value: 4.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 217 DGIAHELrtplVRLRYRLEMSENLTEAESQALNRDIGQLEALIEELLTYAR----LDRPQNelnLSTPDLPAWLQTHIDD 292
Cdd:COG4585 63 DGVGQSL----SAIKLQLEAARRLLDADPEAAREELEEIRELAREALAELRrlvrGLRPPA---LDDLGLAAALEELAER 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 293 VQSVNPQRTLLTrvTPGDYGALDMRLME---RVLDNLMNNAMRYSE-STLQIGLDLQGNQASLTVEDDGPGIAPEaretv 368
Cdd:COG4585 136 LLRAAGIRVELD--VDGDPDRLPPEVELalyRIVQEALTNALKHAGaTRVTVTLEVDDGELTLTVRDDGVGFDPE----- 208
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 556496302 369 fepfvrldpsrdrATGGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:COG4585 209 -------------AAPGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLPL 249
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
205-422 |
9.46e-12 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 67.45 E-value: 9.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 205 INALIAsKKQLIDGIAHELRTPLVRLRYRLEM--SENLTE---AESQALNRDIGQ-LEALIEELLTYARLDRPQNELNLS 278
Cdd:PRK09959 706 INATVA-KSQFLATMSHEIRTPISSIMGFLELlsGSGLSKeqrVEAISLAYATGQsLLGLIGEILDVDKIESGNYQLQPQ 784
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 279 TPDLPAWLQTHIDDVQSVNPQRTL---LTRVTPGDYGA-LDMRLMERVLDNLMNNAMRYS-ESTLQIGLDL---QGNQA- 349
Cdd:PRK09959 785 WVDIPTLVQNTCHSFGAIAASKSIalsCSSTFPDHYLVkIDPQAFKQVLSNLLSNALKFTtEGAVKITTSLghiDDNHAv 864
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556496302 350 -SLTVEDDGPGIAPEARETVFEPFVRLDPSRDRAtgGCGLGLAIVHSIAQAMGGTVHCEESELGGARFCFSWPV 422
Cdd:PRK09959 865 iKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPV 936
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
219-423 |
2.17e-11 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 65.27 E-value: 2.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 219 IAHELRTPLVRLRYRLE-MSENLTEAESQ------ALNrDIGQLEALIEELLTYARldrPQNElNLSTPDLPAWLQTHID 291
Cdd:COG5806 208 IAHEVRNPLTVVRGFIQlLQEPELSDEKRkqyiriALE-ELDRAEAIITDYLTFAK---PQPE-KLEKIDVSEELEHVID 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 292 ------DVQSVnpqrTLLTRVTPGDYGALDMRLMERVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPE 363
Cdd:COG5806 283 vlspyaNMNNV----EIQTELEPGLYIEGDRQKLQQCLINIIKNGIEAMPNggTLTIDVSIDKNKVIISIKDTGVGMTKE 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556496302 364 ARETVFEPFVRLdpsrdrATGGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWPVY 423
Cdd:COG5806 359 QLERLGEPYFST------KEKGTGLGTMVSYRIIEAMNGTIRV-ESEVGkGTTFTITLPLA 412
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
315-414 |
3.41e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 59.78 E-value: 3.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYSESTLQIGLDLQGNQASLT--VEDDGPGIAPEARETVFEPFVRLDPSRDrATGGCGLGLAI 392
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYfeIWDNGHGFSEQDLKKALELFYRDDTSRR-SGGHYGMGLYI 79
|
90 100
....*....|....*....|..
gi 556496302 393 VHSIAQAMGGTVHCEESELGGA 414
Cdd:cd16975 80 AKNLVEKHGGSLIIENSQKGGA 101
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
214-423 |
4.03e-11 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 64.61 E-value: 4.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 214 QLIDGIAHELRTPLVRLRYRLE-MSENLTEAESQALN---RDIGQLEALIEELLTyarLDRPQnELNLSTPDLpawlQTH 289
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKGFIQlLKDTIDEEQKTYLDimlSELDRIESIISEFLV---LAKPQ-AIKYEPKDL----NTL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 290 IDDVQS-VNPQrTLLTRV---------TPGDYGalDMRLMERVLDNLMNNAMrysES-------TLQIGLDLQgNQASLT 352
Cdd:COG5809 344 IEEVIPlLQPQ-ALLKNVqieleleddIPDILG--DENQLKQVFINLLKNAI---EAmpeggniTIETKAEDD-DKVVIS 416
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556496302 353 VEDDGPGIAPEARETVFEPFvrldpsrdrAT---GGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWPVY 423
Cdd:COG5809 417 VTDEGCGIPEERLKKLGEPF---------YTtkeKGTGLGLMVSYKIIEEHGGKITV-ESEVGkGTTFSITLPIK 481
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
318-404 |
1.58e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 57.86 E-value: 1.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 318 LMERVLDNLMNNAMRYSES--TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLdPSRDRATGGCGLGLAIVHS 395
Cdd:cd16945 4 LLRQAINNLLDNAIDFSPEggLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSL-PRPHSGQKSTGLGLAFVQE 82
|
....*....
gi 556496302 396 IAQAMGGTV 404
Cdd:cd16945 83 VAQLHGGRI 91
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
219-421 |
1.34e-09 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 60.14 E-value: 1.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 219 IAHELRTPLVRLRYRLEM--SENLTEAESQALNR---DIGQLEALIEELLTYARLDRPQNELNLSTPDLPAWLQTHIDDV 293
Cdd:TIGR03785 492 LSHELRTPVAVVRSSLENleLQALEQEKQKYLERareGTERLSMILNNMSEATRLEQAIQSAEVEDFDLSEVLSGCMQGY 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 294 QSVNPQRTLltrVTPGDYGALDMR----LMERVLDNLMNNAMRYS--ESTLQIGLDLQGNQASLTVEDDGPGIAPEARET 367
Cdd:TIGR03785 572 QMTYPPQRF---ELNIPETPLVMRgspeLIAQMLDKLVDNAREFSpeDGLIEVGLSQNKSHALLTVSNEGPPLPEDMGEQ 648
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 556496302 368 VFEPFVRLDPSRDRATGGCGLGLAIVHSIAQAMGGTVHCE-ESELGGARFCFSWP 421
Cdd:TIGR03785 649 LFDSMVSVRDQGAQDQPHLGLGLYIVRLIADFHQGRIQAEnRQQNDGVVFRISLP 703
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
218-416 |
2.47e-09 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 59.31 E-value: 2.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 218 GIAHELRTPLVRLRYRLEMSENlTEAESQALNRDIGQLEA-------LIEELLTYAR-LDRPQNELNLST------PDLP 283
Cdd:PRK13837 456 GIAHNFNNILGAILGYAEMALN-KLARHSRAARYIDEIISagararlIIDQILAFGRkGERNTKPFDLSElvteiaPLLR 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 284 AWLQTHIddvqsvnpqrTLLTRVTPGDYGALDMRL-MERVLDNLMNNAMRYSE--STLQIGLDLQ--------------- 345
Cdd:PRK13837 535 VSLPPGV----------ELDFDQDQEPAVVEGNPAeLQQVLMNLCSNAAQAMDgaGRVDISLSRAklrapkvlshgvlpp 604
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556496302 346 GNQASLTVEDDGPGIAPEARETVFEPFVrldpsRDRAtGGCGLGLAIVHSIAQAMGGTVHCeESELG-GARF 416
Cdd:PRK13837 605 GRYVLLRVSDTGAGIDEAVLPHIFEPFF-----TTRA-GGTGLGLATVHGIVSAHAGYIDV-QSTVGrGTRF 669
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
316-424 |
1.32e-08 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 57.29 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 316 MRLmERVLDNLMNNAMRYSES---TLQIGLDlqGNQASLTVEDDGPGIapEARETV--FEPFVRLDPSRDRATGGCGLGL 390
Cdd:PRK10841 561 MRL-QQVISNLLSNAIKFTDTgciVLHVRVD--GDYLSFRVRDTGVGI--PAKEVVrlFDPFFQVGTGVQRNFQGTGLGL 635
|
90 100 110
....*....|....*....|....*....|....*
gi 556496302 391 AIVHSIAQAMGGTVHCeESELG-GARFCFSWPVYH 424
Cdd:PRK10841 636 AICEKLINMMDGDISV-DSEPGmGSQFTIRIPLYG 669
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
318-422 |
2.25e-08 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 56.07 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 318 LMERVLDNLMNNAMRYSEstLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRDRatgGCGLGLAIVHSIA 397
Cdd:TIGR02938 395 LVDNAIEAMNIKGWKRRE--LSITTALNGDLIVVSILDSGPGIPQDLRYKVFEPFFTTKGGSRK---HIGMGLSVAQEIV 469
|
90 100
....*....|....*....|....*
gi 556496302 398 QAMGGTVHCEESELGGARFCFSWPV 422
Cdd:TIGR02938 470 ADHGGIIDLDDDYSEGCRIIVEFRV 494
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
211-269 |
2.80e-08 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 50.29 E-value: 2.80e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556496302 211 SKKQLIDGIAHELRTPLVRLRYRLEMSENLTEAESQA-----LNRDIGQLEALIEELLTYARLD 269
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQReyletILRSAERLLRLINDLLDLSRIE 64
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
346-421 |
3.22e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 51.61 E-value: 3.22e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556496302 346 GNQASLTVEDDGPGIAPEARETVFEPFVRLDPsrdrATGGCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWP 421
Cdd:cd16919 45 GNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKE----VGKGTGLGLSMVYGFVKQSGGHLRI-YSEPGvGTTVRIYLP 116
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
207-402 |
3.62e-08 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 55.46 E-value: 3.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 207 ALIASKKQLIDGIAHELRTPLVRLRYRLEMSENLTEAESQALNRD-IGQLEALIEelltyaRLDRPQNEL-----NLSTP 280
Cdd:COG4192 428 AKMAVVGQTMTSLAHELNQPLNAMSMYLFSAKKALEQENYAQLPTsLDKIEGLIE------RMDKIIKSLrqfsrKSDTP 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 281 DLPAWLQTHIDD----VQSVN-PQRTLLTrvTPGDYGAL-DMRLMERVLDNLMNNAMRYSESTLQIGLDLQGNQASLT-- 352
Cdd:COG4192 502 LQPVDLRQVIEQawelVESRAkPQQITLH--IPDDLMVQgDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRva 579
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 556496302 353 VEDDGPGIApeARETVFEPFVrldpsrDRATGGCGLGLAIVHSIAQAMGG 402
Cdd:COG4192 580 ISDNGNGWP--LVDKLFTPFT------TTKEVGLGLGLSICRSIMQQFGG 621
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
211-269 |
7.40e-08 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 49.10 E-value: 7.40e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556496302 211 SKKQLIDGIAHELRTPLVRLRYRLEM--SENLTEAESQALN---RDIGQLEALIEELLTYARLD 269
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELllDTELSEEQREYLEtilREAERLLRLINDLLDLSRIE 64
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
315-421 |
8.12e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 50.36 E-value: 8.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 315 DMRLMERVLDNLMNNAMRYS--ESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRdRATGGCGLGLAI 392
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSkqGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGR-NFQESTGMGLYL 80
|
90 100
....*....|....*....|....*....
gi 556496302 393 VHSIAQAMGGTVHCEESELGGARFCFSWP 421
Cdd:cd16948 81 VKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
166-205 |
2.37e-07 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 47.05 E-value: 2.37e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 556496302 166 KLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNI 205
Cdd:cd06225 6 RLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
164-210 |
3.14e-07 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 46.86 E-value: 3.14e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 556496302 164 MLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIA 210
Cdd:smart00304 7 LRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
321-421 |
4.00e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 47.55 E-value: 4.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 321 RVLDNLMNNAMRYSE-STLQIGLDLQGNQASLTVEDDGPGIAPEAREtvfepfvrldpsrdratGGCGLGLAIVHSIAQA 399
Cdd:cd16917 3 RIVQEALTNALKHAGaSRVRVTLSYTADELTLTVVDDGVGFDGPAPP-----------------GGGGFGLLGMRERAEL 65
|
90 100
....*....|....*....|..
gi 556496302 400 MGGTVHCEESELGGARFCFSWP 421
Cdd:cd16917 66 LGGTLTIGSRPGGGTRVTARLP 87
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
209-267 |
4.50e-07 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 46.82 E-value: 4.50e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556496302 209 IASKKQLIDGIAHELRTPLVRLRYRLEMSENLTEAES------QALNRDIGQLEALIEELLTYAR 267
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEeqreylERIREEAERLLRLINDLLDLSR 65
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
316-421 |
6.53e-07 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 51.77 E-value: 6.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 316 MRLmERVLDNLMNNAMRYSES-TLQIGLDLQ---GNQASLTVE--DDGPGIAPEARETVFEPFVRLDPSRDRATGGCGLG 389
Cdd:PRK11107 407 LRL-QQIITNLVGNAIKFTESgNIDILVELRalsNTKVQLEVQirDTGIGISERQQSQLFQAFRQADASISRRHGGTGLG 485
|
90 100 110
....*....|....*....|....*....|...
gi 556496302 390 LAIVHSIAQAMGGTVHCeESELG-GARFCFSWP 421
Cdd:PRK11107 486 LVITQKLVNEMGGDISF-HSQPNrGSTFWFHLP 517
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
1-422 |
8.99e-07 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 50.79 E-value: 8.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 1 MKKLFVQFYLLLFVCFLVMTMLVGLVYKFTAERAGRQSLDDLMKSSLYLMRSELREIPPHDWAKTLKELDLNLSFDLRIE 80
Cdd:COG2972 15 LILLLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLILLLLLLLLLLLI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 81 PLKDFDLDPPAMQRLRDGDIVALDEKYTFIQRIPRSHYVL----AVGPVPYLYYLHQMRLLDMALMAFIAISLAFPVFIW 156
Cdd:COG2972 95 LLLSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLlgwtLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLS 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 157 MRPHW---QDMLKLESAAQRFGEGHFTeRIHFDSGSSFERLGVAFNQMADNINALIASKKQLidgiahELRtpLVRLRYR 233
Cdd:COG2972 175 YLLSRsitRPIKRLKKAMKKVEKGDLV-RLEVSGNDEIGILARSFNEMVERIKELIEEVYEL------ELE--KKEAELK 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 234 -LEMSEN-------LTEAESQALNRDIGQLEALIEELLTYARLdrpqnelNLSTPDLPAWLQTHIDDVQS-VNPQR---- 300
Cdd:COG2972 246 aLQAQINphflfntLNSIRWLAELEDPEEAEEMLEALSKLLRY-------SLSKGDELVTLEEELELIKSyLEIQKlrfg 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 301 ---TLLTRVTPGDYGALDMRLMervLDNLMNNAMRYSES------TLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEP 371
Cdd:COG2972 319 drlEVEIEIDEELLDLLIPKLI---LQPLVENAIEHGIEpkegggTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEE 395
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 556496302 372 FVRLDPSRdratggcGLGLAIVHSIAQAM---GGTVHCEESELGGARFCFSWPV 422
Cdd:COG2972 396 LSSKGEGR-------GIGLRNVRERLKLYygeEYGLEIESEPGEGTTVTIRIPL 442
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
212-422 |
9.59e-07 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 51.09 E-value: 9.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 212 KKQLIDGIAHELRTPL---VRLRyRLEMSENLTEAESQALN-------------RDIGQLEalieelltyaRLDRPQNEL 275
Cdd:PRK11091 283 KTTFISTISHELRTPLngiVGLS-RILLDTELTAEQRKYLKtihvsaitlgnifNDIIDMD----------KMERRKLQL 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 276 NLSTPDLPAWlqthIDDVQSVN----PQRTL---LTRVTP-GDYGALDMRLMERVLDNLMNNAMRYS---ESTLQIGLDl 344
Cdd:PRK11091 352 DNQPIDFTDF----LADLENLSglqaEQKGLrfdLEPLLPlPHKVITDGTRLRQILWNLISNAVKFTqqgGVTVRVRYE- 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 345 QGNQASLTVEDDGPGIAPEARETVFEPFVRLDPSRD--RATGgCGLGLAIVHSIAQAMGGTVHCeESELG-GARFCFSWP 421
Cdd:PRK11091 427 EGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDSHGgkPATG-TGIGLAVSKRLAQAMGGDITV-TSEEGkGSCFTLTIH 504
|
.
gi 556496302 422 V 422
Cdd:PRK11091 505 A 505
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
193-421 |
1.95e-06 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 49.69 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 193 RLGVAFNQMADNINAliaskKQLIDGIAHELRTPLVRLRYRLEMSEN------LTEAeSQALNRDIGQLEALIEELLTya 266
Cdd:PRK11073 116 RLSQEQLQHAQQVAA-----RDLVRGLAHEIKNPLGGLRGAAQLLSKalpdpaLTEY-TKVIIEQADRLRNLVDRLLG-- 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 267 rldrPQNELNLSTPDLPAWLQTHIDDVQSVNPQRTLLTRvtpgDYG------ALDMRLMERVLDNLMNNAM-----RYSE 335
Cdd:PRK11073 188 ----PQRPGTHVTESIHKVAERVVQLVSLELPDNVRLIR----DYDpslpelAHDPDQIEQVLLNIVRNALqalgpEGGT 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 336 STLQIGLDLQGN--------QASLTVEDDGPGIAPEARETVFEPFVRldpSRDratGGCGLGLAIVHSIAQAMGGTVHCE 407
Cdd:PRK11073 260 ITLRTRTAFQLTlhgeryrlAARIDIEDNGPGIPPHLQDTLFYPMVS---GRE---GGTGLGLSIARNLIDQHSGKIEFT 333
|
250
....*....|....
gi 556496302 408 eselggarfcfSWP 421
Cdd:PRK11073 334 -----------SWP 336
|
|
| HAMP |
pfam00672 |
HAMP domain; |
157-207 |
4.42e-06 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 43.77 E-value: 4.42e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 556496302 157 MRPHWQDMLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINA 207
Cdd:pfam00672 3 ARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
334-432 |
8.33e-06 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 48.13 E-value: 8.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 334 SESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVrldPSRDRATgGCGLGLAIVHSIAQAMGGTVHCEESELGG 413
Cdd:PRK13557 310 DEDLAMYHGLPPGRYVSIAVTDTGSGMPPEILARVMDPFF---TTKEEGK-GTGLGLSMVYGFAKQSGGAVRIYSEVGEG 385
|
90
....*....|....*....
gi 556496302 414 ARFCFSWPVYHNIALPVPA 432
Cdd:PRK13557 386 TTVRLYFPASDQAENPEQE 404
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
131-262 |
1.35e-05 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 47.32 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 131 LHQMRLLDMALMAFIAISLAFPVFIwMRPHWQDMLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIA 210
Cdd:COG0840 178 ALALALLAAALLALVALAIILALLL-SRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVG 256
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 556496302 211 SKKQLIDGI---AHELRtplvrlryrlEMSENLTE-AESQAlnRDIGQLEALIEEL 262
Cdd:COG0840 257 QVRESAEQVasaSEELA----------ASAEELAAgAEEQA--ASLEETAAAMEEL 300
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
322-407 |
1.68e-05 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 43.03 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 322 VLDNLMNNAMRY-----SESTLQIGLDLQGNQASLTVEDDGPGiapearetvFEPFVRLDPSRDRATGGcgLGLAIVHSI 396
Cdd:cd16936 4 AVSEAVTNAVRHayrhdGPGPVRLELDLDPDRLRVEVTDSGPG---------FDPLRPADPDAGLREGG--RGLALIRAL 72
|
90
....*....|....*...
gi 556496302 397 A-------QAMGGTVHCE 407
Cdd:cd16936 73 MdevgyrrTPGGKTVWLE 90
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
326-404 |
1.94e-05 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 43.75 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 326 LMNNAMRY-----SESTLQIGLDLQGNQASLTVEDDGPGIAPEAREtvfepfvrlDPSRDRATGgcGLGLAIVHSIAQAM 400
Cdd:COG2172 42 AVTNAVRHayggdPDGPVEVELELDPDGLEIEVRDEGPGFDPEDLP---------DPYSTLAEG--GRGLFLIRRLMDEV 110
|
90
....*....|
gi 556496302 401 ------GGTV 404
Cdd:COG2172 111 eyesdpGGTT 120
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
326-422 |
2.83e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 46.44 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 326 LMNNAMRY-----SESTLQIGLDLQGNQASLTVEDDGPGIAPEAretvfepfvrlDPSRDRatggcGLGLAIVHSIAQAM 400
Cdd:COG3920 407 LVTNALKHaflsgEGGRIRVSWRREDGRLRLTVSDNGVGLPEDV-----------DPPARK-----GLGLRLIRALVRQL 470
|
90 100
....*....|....*....|..
gi 556496302 401 GGTVHCEESElgGARFCFSWPV 422
Cdd:COG3920 471 GGTLELDRPE--GTRVRITFPL 490
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
70-270 |
2.94e-05 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 46.03 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 70 DLNLSFDLRIEPLKDFDLDPPAMQRLRDGDIVALDEKYTFIQRIPRSHYVLAVGPVPYLYYLHQMRLLDMALMAFIAISL 149
Cdd:COG3850 51 SAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 150 AFPVFIWMRPHW-QDMLKLESAAQRFGEGHFTERIHFDSGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLV 228
Cdd:COG3850 131 ALLLAYLLRRRIvRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALL 210
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 556496302 229 RLRYRLEMSENLTEAESQALNRDIGQLEALIEELLTYARLDR 270
Cdd:COG3850 211 DELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESE 252
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
22-275 |
5.79e-05 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 45.49 E-value: 5.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 22 LVGLVYKFTAERAGRQSLDDLMKSSLYLMRSELREIPPHDWAKTLKELDLNLSFDLRIEPLKDFDLDPPAMQRLRDGDIV 101
Cdd:COG2770 97 LLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 102 ALDEKYTFIQRIPRSHYVLAVGPVPYLYYLHQMRLLDMALMAFIAISLAFPVFIWM-----RPhwqdMLKLESAAQRFGE 176
Cdd:COG2770 177 ADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLarritRP----LRRLAEAARRIAA 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 177 GHFTERIHFDSGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSENLTEAESQALNRDIGQLE 256
Cdd:COG2770 253 GDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLEL 332
|
250
....*....|....*....
gi 556496302 257 ALIEELLTYARLDRPQNEL 275
Cdd:COG2770 333 LLLLLLALLLLLLLAADLL 351
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
322-412 |
7.73e-05 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 44.90 E-value: 7.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 322 VLDNLMNNAM----RYSESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEpfvrldpsRDRATGGC--GLGLAIVHS 395
Cdd:PRK11086 437 ILGNLIENALeavgGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFD--------KGYSTKGSnrGVGLYLVKQ 508
|
90
....*....|....*..
gi 556496302 396 IAQAMGGTVHCeESELG 412
Cdd:PRK11086 509 SVENLGGSIAV-ESEPG 524
|
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
313-397 |
5.70e-04 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 39.58 E-value: 5.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 313 ALDMRLmerVLDNLMNNAMRY-----SESTLQIGLDLQGNQASLTVEDDGPGIAPEARetvfEPFVRLDPSRDRATGgcG 387
Cdd:pfam13581 29 LDEVEL---AVGEACTNAVEHayregPEGPVEVRLTSDGGGLVVTVADSGPPFDPLTL----PPPDLEEPDEDRKEG--G 99
|
90
....*....|
gi 556496302 388 LGLAIVHSIA 397
Cdd:pfam13581 100 RGLALIRGLM 109
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
322-424 |
8.91e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 41.36 E-value: 8.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556496302 322 VLDNLMNNAMRYS------ESTLQIGLDLQGNQASLTVEDDGPGIAPEARETVFEPFVRldpSRDRATGGCGLGLAIVHS 395
Cdd:PRK15053 436 IVGNLLDNAFEASlrsdegNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVS---TRADEPGEHGIGLYLIAS 512
|
90 100
....*....|....*....|....*....
gi 556496302 396 IAQAMGGTVHCEESELGGARFCFSWPVYH 424
Cdd:PRK15053 513 YVTRCGGVITLEDNDPCGTLFSIFIPKVK 541
|
|
| |
