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Conserved domains on  [gi|556491228|ref|WP_023338954|]
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MULTISPECIES: lactonase family protein [Enterobacter]

Protein Classification

lactonase family protein( domain architecture ID 11457674)

lactonase family protein similar to 6-phosphogluconolactonase which\ncatalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the oxidative phase of the pentose phosphate pathway

CATH:  2.130.10.10
Gene Ontology:  GO:0052689
SCOP:  4002745|4000933

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
22-376 1.94e-136

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


:

Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 393.12  E-value: 1.94e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  22 TQYAWVGTYN-PNGEGLYRFTVDAQTGALGNKTLVSKLPNAAQLAVSHDGKTLYLASEVEQGVVQALRVE-DNGELSELN 99
Cdd:COG2706    7 STFVYVGTYTsGESEGIYVFRLDTATGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVDDGGVSAFRIDpADGTLTLLN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 100 QVASGGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGDATDKHQDQGepgaakpeaaveGSFAISDHNGPHAHM 179
Cdd:COG2706   87 TVSSGGASPCHLSVDPDGRFLFVANYGGGSVSVFPIDADGSLGEPVQVIQHEG------------SGPNPERQEGPHAHS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 180 IAADPSGKYVFSTDLGLDRIYQYRFDDRSGKLTPndPPFISAsSKGAGPRHFVFTPKGDALWLINEEASTLTHYTVNA-N 258
Cdd:COG2706  155 VVFDPDGRFLYVPDLGTDRIYVYRLDPATGKLPE--PPEVSL-PPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAaT 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 259 GTLKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSIGHFTVTAE-GTLRHQDDVWTRGDYPRTLTLDKQGRW 337
Cdd:COG2706  232 GTLTLIQTVSTLPEDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADgGKLTLVGHVPTGGKWPRDFAIDPDGRF 311

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 556491228 338 LYVMNQRSDNITRFRV-AQDGKLSFEPDYTPVGSPSQMVI 376
Cdd:COG2706  312 LLVANQKSDNITVFRIdADTGKLTPTGRSVPVPSPVCVAF 351
 
Name Accession Description Interval E-value
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
22-376 1.94e-136

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 393.12  E-value: 1.94e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  22 TQYAWVGTYN-PNGEGLYRFTVDAQTGALGNKTLVSKLPNAAQLAVSHDGKTLYLASEVEQGVVQALRVE-DNGELSELN 99
Cdd:COG2706    7 STFVYVGTYTsGESEGIYVFRLDTATGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVDDGGVSAFRIDpADGTLTLLN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 100 QVASGGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGDATDKHQDQGepgaakpeaaveGSFAISDHNGPHAHM 179
Cdd:COG2706   87 TVSSGGASPCHLSVDPDGRFLFVANYGGGSVSVFPIDADGSLGEPVQVIQHEG------------SGPNPERQEGPHAHS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 180 IAADPSGKYVFSTDLGLDRIYQYRFDDRSGKLTPndPPFISAsSKGAGPRHFVFTPKGDALWLINEEASTLTHYTVNA-N 258
Cdd:COG2706  155 VVFDPDGRFLYVPDLGTDRIYVYRLDPATGKLPE--PPEVSL-PPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAaT 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 259 GTLKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSIGHFTVTAE-GTLRHQDDVWTRGDYPRTLTLDKQGRW 337
Cdd:COG2706  232 GTLTLIQTVSTLPEDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADgGKLTLVGHVPTGGKWPRDFAIDPDGRF 311

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 556491228 338 LYVMNQRSDNITRFRV-AQDGKLSFEPDYTPVGSPSQMVI 376
Cdd:COG2706  312 LLVANQKSDNITVFRIdADTGKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 25-372 1.20e-112

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 332.26  E-value: 1.20e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228   25 AWVGTY-NPNGEGLYRFTVDAQTGALGNKTLVSKLPNAAQLAVSHDGKTLYLASEV-EQGVVQALRVE-DNGELSELNQV 101
Cdd:pfam10282   2 LYVGTYtKGDSKGIYVLTLDTETGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEEgDQGGVAAFRIDpDSGALTLLNQV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  102 ASGGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGDATDKHQDQGePGAAKPEaavegsfaisdHNGPHAHMIA 181
Cdd:pfam10282  82 PTGGASPCHLSVDPDGRFLFVANYHGGSVSVFPLDADGSLGELSQVVQHEG-SGPPPER-----------QESPHPHSVD 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  182 ADPSGKYVFSTDLGLDRIYQYRFDDRSGKLTPndPPFIsASSKGAGPRHFVFTPKGDALWLINEEASTLTHYTVN-ANGT 260
Cdd:pfam10282 150 LTPDGKFLVVPDLGTDRVRVYKLDAGGGKLTP--PASV-QTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDpATGT 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  261 LKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSIGHFTVT-AEGTLRHQDDVWTRGDYPRTLTLDKQGRWLY 339
Cdd:pfam10282 227 FEELQTVSTLPEGFTGTNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDeAGGTLTLVERVSTEGDFPRDFNIDPDGKFLV 306

                         330       340       350
                  ....*....|....*....|....*....|....
gi 556491228  340 VMNQRSDNITRFRV-AQDGKLSFEPDYTPVGSPS 372
Cdd:pfam10282 307 VANQDSDNVTVFRRdPETGKLTLLGKDIEVPEPV 340
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 64-369 6.99e-35

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 130.85  E-value: 6.99e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  64 LAVSHDGKTLYLASEVEQGVVqALRVEDNGELSELNQVASGGAgPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGD 143
Cdd:PRK11028  40 MVISPDKRHLYVGVRPEFRVL-SYRIADDGALTFAAESPLPGS-PTHISTDHQGRFLFSASYNANCVSVSPLDKDGIPVA 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 144 ATDkhqdqgepgaakpeaAVEGSFaisdhnGPHAHMIaaDPSGKYVFSTDLGLDRIYQYRFDDrSGKLTPNDPPFISaSS 223
Cdd:PRK11028 118 PIQ---------------IIEGLE------GCHSANI--DPDNRTLWVPCLKEDRIRLFTLSD-DGHLVAQEPAEVT-TV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 224 KGAGPRHFVFTPKGDALWLINEEASTLTHYTVN-ANGTLKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSI 302
Cdd:PRK11028 173 EGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKdPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLI 252

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556491228 303 GHFTVTAEG-TLR---HQDdvwTRgDYPRTLTLDKQGRWLYVMNQRSDNITRFRVAQD-GKLSFEPDYtPVG 369
Cdd:PRK11028 253 SVFSVSEDGsVLSfegHQP---TE-TQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGEtGLLTELGRY-AVG 319
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 64-295 3.06e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 48.50  E-value: 3.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228   64 LAVSHDGKTLYL-ASEVEqgvvqALRVEDNGELSELNQVASgGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLG 142
Cdd:TIGR03866  46 ITFSKDGKLLYVcASDSD-----TIQVIDPATGEVLHTLPS-GPDPEQFALHPNGKILYIANEDDALVTVIDIETRKVLA 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  143 DAtdkhqDQG-EPgaakpeaavEGsfaisdhngphahmIAADPSGKYVFSTdlgldriyqyrfddrsgKLTPNDPPFISA 221
Cdd:TIGR03866 120 QI-----DVGvEP---------EG--------------MAVSPDGKIVVNT-----------------SETTNMAHWIDT 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  222 SSK--------GAGPRHFVFTPKGDALWLINEEASTLTHYTVNangTLKAGKTLS-ALPKGYKGTSFAAGLALSADGKQL 292
Cdd:TIGR03866 155 ATYeivdntlvDARPRFAEFTADGKELWVSSEIGGTVTVIDVA---TRKVIKKITfAIPGVHPEKVQPVGIKLTKDGKTA 231


                  ...
gi 556491228  293 YVA 295
Cdd:TIGR03866 232 FVA 234
 
Name Accession Description Interval E-value
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
22-376 1.94e-136

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 393.12  E-value: 1.94e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  22 TQYAWVGTYN-PNGEGLYRFTVDAQTGALGNKTLVSKLPNAAQLAVSHDGKTLYLASEVEQGVVQALRVE-DNGELSELN 99
Cdd:COG2706    7 STFVYVGTYTsGESEGIYVFRLDTATGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVDDGGVSAFRIDpADGTLTLLN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 100 QVASGGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGDATDKHQDQGepgaakpeaaveGSFAISDHNGPHAHM 179
Cdd:COG2706   87 TVSSGGASPCHLSVDPDGRFLFVANYGGGSVSVFPIDADGSLGEPVQVIQHEG------------SGPNPERQEGPHAHS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 180 IAADPSGKYVFSTDLGLDRIYQYRFDDRSGKLTPndPPFISAsSKGAGPRHFVFTPKGDALWLINEEASTLTHYTVNA-N 258
Cdd:COG2706  155 VVFDPDGRFLYVPDLGTDRIYVYRLDPATGKLPE--PPEVSL-PPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAaT 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 259 GTLKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSIGHFTVTAE-GTLRHQDDVWTRGDYPRTLTLDKQGRW 337
Cdd:COG2706  232 GTLTLIQTVSTLPEDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADgGKLTLVGHVPTGGKWPRDFAIDPDGRF 311

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 556491228 338 LYVMNQRSDNITRFRV-AQDGKLSFEPDYTPVGSPSQMVI 376
Cdd:COG2706  312 LLVANQKSDNITVFRIdADTGKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 25-372 1.20e-112

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 332.26  E-value: 1.20e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228   25 AWVGTY-NPNGEGLYRFTVDAQTGALGNKTLVSKLPNAAQLAVSHDGKTLYLASEV-EQGVVQALRVE-DNGELSELNQV 101
Cdd:pfam10282   2 LYVGTYtKGDSKGIYVLTLDTETGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEEgDQGGVAAFRIDpDSGALTLLNQV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  102 ASGGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGDATDKHQDQGePGAAKPEaavegsfaisdHNGPHAHMIA 181
Cdd:pfam10282  82 PTGGASPCHLSVDPDGRFLFVANYHGGSVSVFPLDADGSLGELSQVVQHEG-SGPPPER-----------QESPHPHSVD 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  182 ADPSGKYVFSTDLGLDRIYQYRFDDRSGKLTPndPPFIsASSKGAGPRHFVFTPKGDALWLINEEASTLTHYTVN-ANGT 260
Cdd:pfam10282 150 LTPDGKFLVVPDLGTDRVRVYKLDAGGGKLTP--PASV-QTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDpATGT 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  261 LKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSIGHFTVT-AEGTLRHQDDVWTRGDYPRTLTLDKQGRWLY 339
Cdd:pfam10282 227 FEELQTVSTLPEGFTGTNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDeAGGTLTLVERVSTEGDFPRDFNIDPDGKFLV 306

                         330       340       350
                  ....*....|....*....|....*....|....
gi 556491228  340 VMNQRSDNITRFRV-AQDGKLSFEPDYTPVGSPS 372
Cdd:pfam10282 307 VANQDSDNVTVFRRdPETGKLTLLGKDIEVPEPV 340
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 64-369 6.99e-35

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 130.85  E-value: 6.99e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  64 LAVSHDGKTLYLASEVEQGVVqALRVEDNGELSELNQVASGGAgPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGD 143
Cdd:PRK11028  40 MVISPDKRHLYVGVRPEFRVL-SYRIADDGALTFAAESPLPGS-PTHISTDHQGRFLFSASYNANCVSVSPLDKDGIPVA 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 144 ATDkhqdqgepgaakpeaAVEGSFaisdhnGPHAHMIaaDPSGKYVFSTDLGLDRIYQYRFDDrSGKLTPNDPPFISaSS 223
Cdd:PRK11028 118 PIQ---------------IIEGLE------GCHSANI--DPDNRTLWVPCLKEDRIRLFTLSD-DGHLVAQEPAEVT-TV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 224 KGAGPRHFVFTPKGDALWLINEEASTLTHYTVN-ANGTLKAGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSI 302
Cdd:PRK11028 173 EGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKdPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLI 252

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556491228 303 GHFTVTAEG-TLR---HQDdvwTRgDYPRTLTLDKQGRWLYVMNQRSDNITRFRVAQD-GKLSFEPDYtPVG 369
Cdd:PRK11028 253 SVFSVSEDGsVLSfegHQP---TE-TQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGEtGLLTELGRY-AVG 319
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
100-375 2.74e-14

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 72.36  E-value: 2.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 100 QVASGGAGPVYLSLTPNGQhLLVANYVSGSIAVLpvkadgslgDATDKHQDQgepgaakpeaavegsFAISDHNGPHAhm 179
Cdd:COG4257   11 PVPAPGSGPRDVAVDPDGA-VWFTDQGGGRIGRL---------DPATGEFTE---------------YPLGGGSGPHG-- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 180 IAADPSGKyVFSTDLGLDRIYqyRFDDRSGKLTPndppfISASSKGAGPRHFVFTPKGDaLWLINEEASTLTHYTVnANG 259
Cdd:COG4257   64 IAVDPDGN-LWFTDNGNNRIG--RIDPKTGEITT-----FALPGGGSNPHGIAFDPDGN-LWFTDQGGNRIGRLDP-ATG 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 260 TLKagktlsaLPKGYKGTSFAAGLALSADGKqLYVANRLHNSIGHFTvTAEGTLRHQDdVWTRGDYPRTLTLDKQGRwLY 339
Cdd:COG4257  134 EVT-------EFPLPTGGAGPYGIAVDPDGN-LWVTDFGANAIGRID-PDTGTLTEYA-LPTPGAGPRGLAVDPDGN-LW 202

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 556491228 340 VMNQRSDNITRFRvAQDGKLSFEPDYTPVGSPSQMV 375
Cdd:COG4257  203 VADTGSGRIGRFD-PKTGTVTEYPLPGGGARPYGVA 237
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
39-301 1.48e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 60.86  E-value: 1.48e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  39 RFTVDAQTGALGNKTLVSKLPNAAQLAVSHDGKTLYLASEVEQGVVQALRVEDNGELSELNQVASGGAGPVYLSLTPNGQ 118
Cdd:COG3391    1 ALVASSLLVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 119 HLLVANYVSGSIAVLpvkadgslgDATDkhqdqgepgaakpeAAVEGSFAIsdhnGPHAHMIAADPSGKYVFSTDLGLDR 198
Cdd:COG3391   81 RLYVANSGSGRVSVI---------DLAT--------------GKVVATIPV----GGGPRGLAVDPDGGRLYVADSGNGR 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 199 IyqYRFDDRSGKLtpndppfISASSKGAGPRHFVFTPKGDALWLINEEASTLTHYTVNANgtLKAGKTLSALPKGykgtS 278
Cdd:COG3391  134 V--SVIDTATGKV-------VATIPVGAGPHGIAVDPDGKRLYVANSGSNTVSVIVSVID--TATGKVVATIPVG----G 198

                        250       260
                 ....*....|....*....|...
gi 556491228 279 FAAGLALSADGKQLYVANRLHNS 301
Cdd:COG3391  199 GPVGVAVSPDGRRLYVANRGSNT 221
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
214-351 8.22e-08

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 52.77  E-value: 8.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 214 NDPPFISASSKGAGPRHFVFTPKGDALWLINEEASTLTHYTvnangtLKAGKTLSALPKGykgtSFAAGLALSADGKQLY 293
Cdd:COG3391   56 LLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVID------LATGKVVATIPVG----GGPRGLAVDPDGGRLY 125

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 556491228 294 VANRLHNSIGHFTvTAEGTLRHQddvWTRGDYPRTLTLDKQGRWLYVMNQRSDNITRF 351
Cdd:COG3391  126 VADSGNGRVSVID-TATGKVVAT---IPVGAGPHGIAVDPDGKRLYVANSGSNTVSVI 179
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 64-295 3.06e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 48.50  E-value: 3.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228   64 LAVSHDGKTLYL-ASEVEqgvvqALRVEDNGELSELNQVASgGAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLG 142
Cdd:TIGR03866  46 ITFSKDGKLLYVcASDSD-----TIQVIDPATGEVLHTLPS-GPDPEQFALHPNGKILYIANEDDALVTVIDIETRKVLA 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  143 DAtdkhqDQG-EPgaakpeaavEGsfaisdhngphahmIAADPSGKYVFSTdlgldriyqyrfddrsgKLTPNDPPFISA 221
Cdd:TIGR03866 120 QI-----DVGvEP---------EG--------------MAVSPDGKIVVNT-----------------SETTNMAHWIDT 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  222 SSK--------GAGPRHFVFTPKGDALWLINEEASTLTHYTVNangTLKAGKTLS-ALPKGYKGTSFAAGLALSADGKQL 292
Cdd:TIGR03866 155 ATYeivdntlvDARPRFAEFTADGKELWVSSEIGGTVTVIDVA---TRKVIKKITfAIPGVHPEKVQPVGIKLTKDGKTA 231


                  ...
gi 556491228  293 YVA 295
Cdd:TIGR03866 232 FVA 234
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 180-359 4.11e-06

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 47.58  E-value: 4.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 180 IAADPSGK-YVFSTDLGLdriyqYRFDDRSGKLTP----NDPPFISasskgagPRHFVFTPKGdALWlineeASTLTHYT 254
Cdd:COG3386   54 LAFDPDGRlLVADHGRGL-----VRFDPADGEVTVladeYGKPLNR-------PNDGVVDPDG-RLY-----FTDMGEYL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 255 vnANGTL---KAGKTLSALPKGYkgtSFAAGLALSADGKQLYVANRLHNSIGHFTVTAEGTLRHQD---DVWTRGDYPRT 328
Cdd:COG3386  116 --PTGALyrvDPDGSLRVLADGL---TFPNGIAFSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRvfaDLPDGPGGPDG 190

                        170       180       190
                 ....*....|....*....|....*....|.
gi 556491228 329 LTLDKQGRwLYVMNQRSDNITRFrvAQDGKL 359
Cdd:COG3386  191 LAVDADGN-LWVALWGGGGVVRF--DPDGEL 218
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
263-378 8.11e-06

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 46.61  E-value: 8.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 263 AGKTLSALPKGYKGTSFAAGLALSADGKQLYVANRLHNSIGHFTvTAEGTLRHQddvWTRGDYPRTLTLDKQGRWLYVMN 342
Cdd:COG3391   53 GVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVID-LATGKVVAT---IPVGGGPRGLAVDPDGGRLYVAD 128

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 556491228 343 QRSDNITRFRVAqDGKLsfePDYTPVG-SPSQMVISP 378
Cdd:COG3391  129 SGNGRVSVIDTA-TGKV---VATIPVGaGPHGIAVDP 161
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 25-213 5.66e-04

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 40.04  E-value: 5.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  25 AWVGTYNPNGEgLYrfTVDAQTGALgnKTLVSKLPNAAQLAVSHDGKTLYLASEvEQGVVQALRVEDNGelSELNQVASG 104
Cdd:COG0823    2 AFTLSRDGNSD-IY--VVDLDGGEP--RRLTNSPGIDTSPAWSPDGRRIAFTSD-RGGGPQIYVVDADG--GEPRRLTFG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228 105 GAGPVYLSLTPNGQHLLVANYVSGSIAVLPVKADGslGDATDKHQDQGEPgaakpeaavegSFAisdhngphahmiaadP 184
Cdd:COG0823   74 GGYNASPSWSPDGKRLAFVSRSDGRFDIYVLDLDG--GAPRRLTDGPGSP-----------SWS---------------P 125

                        170       180       190
                 ....*....|....*....|....*....|.
gi 556491228 185 SGKYVF--STDLGLDRIYQYRFDDRSGKLTP 213
Cdd:COG0823  126 DGRRIVfsSDRGGRPDLYVVDLDGRKRRLTP 156
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 33-157 1.38e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 39.88  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  33 NGEGLYRFtvDAQTGALgnKTLVSKLPNAAQ----LAVSHDGkTLYLASEVEQGVVQAL-RVEDNGELSelnQVASGGAG 107
Cdd:COG3386   67 HGRGLVRF--DPADGEV--TVLADEYGKPLNrpndGVVDPDG-RLYFTDMGEYLPTGALyRVDPDGSLR---VLADGLTF 138

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 556491228 108 PVYLSLTPNGQHLLVANYVSGSIAVLPVKADGSLGDAT---DKHQDQGEP-GAA 157
Cdd:COG3386  139 PNGIAFSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRvfaDLPDGPGGPdGLA 192
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 282-378 1.98e-03

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 39.64  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556491228  282 GLALSADGKQLYVANRLHNSIGHFTvTAEGTLRHQddvWTRGDYPRTLTLDKQGRWLYVMNQrSDNI-------TRFRVA 354
Cdd:TIGR03866  45 GITFSKDGKLLYVCASDSDTIQVID-PATGEVLHT---LPSGPDPEQFALHPNGKILYIANE-DDALvtvidieTRKVLA 119

                          90       100
                  ....*....|....*....|....*
gi 556491228  355 QdgklsfepdyTPVG-SPSQMVISP 378
Cdd:TIGR03866 120 Q----------IDVGvEPEGMAVSP 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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