NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|556388750|ref|WP_023303127|]
View 

MULTISPECIES: hypothetical protein [Enterobacterales]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HEPN_RES_NTD1 super family cl40151
HEPN/RES N-terminal domain 1; Mostly alpha helical. Fused to HEPN (MAE_28990 superfamily), RES ...
 26-124 1.67e-04

HEPN/RES N-terminal domain 1; Mostly alpha helical. Fused to HEPN (MAE_28990 superfamily), RES domain, a potential RNase found in various toxin systems.


The actual alignment was detected with superfamily member pfam18870:

Pssm-ID: 436794  Cd Length: 131  Bit Score: 40.80  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556388750   26 LEVMRNWFFENFEDPANSCPYESREGGY--AYIYgGPYEASEELQAMFEGYVKFDYIQELVNDLQEQcyEWSGnsnniND 103
Cdd:pfam18870  25 MEFIMEGIRTEYGDAANELPYDSREGGYqgATTW-DTYDLLEDEIGLEADEDDDELLEDIASAIDDD--AWVE-----RD 96

                          90       100
                  ....*....|....*....|.
gi 556388750  104 WYDEDLYDAVTSSEQPFSKFV 124
Cdd:pfam18870  97 PYALSPDEALRYGWEQFCETV 117
 
Name Accession Description Interval E-value
HEPN_RES_NTD1 pfam18870
HEPN/RES N-terminal domain 1; Mostly alpha helical. Fused to HEPN (MAE_28990 superfamily), RES ...
 26-124 1.67e-04

HEPN/RES N-terminal domain 1; Mostly alpha helical. Fused to HEPN (MAE_28990 superfamily), RES domain, a potential RNase found in various toxin systems.


Pssm-ID: 436794  Cd Length: 131  Bit Score: 40.80  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556388750   26 LEVMRNWFFENFEDPANSCPYESREGGY--AYIYgGPYEASEELQAMFEGYVKFDYIQELVNDLQEQcyEWSGnsnniND 103
Cdd:pfam18870  25 MEFIMEGIRTEYGDAANELPYDSREGGYqgATTW-DTYDLLEDEIGLEADEDDDELLEDIASAIDDD--AWVE-----RD 96

                          90       100
                  ....*....|....*....|.
gi 556388750  104 WYDEDLYDAVTSSEQPFSKFV 124
Cdd:pfam18870  97 PYALSPDEALRYGWEQFCETV 117
 
Name Accession Description Interval E-value
HEPN_RES_NTD1 pfam18870
HEPN/RES N-terminal domain 1; Mostly alpha helical. Fused to HEPN (MAE_28990 superfamily), RES ...
 26-124 1.67e-04

HEPN/RES N-terminal domain 1; Mostly alpha helical. Fused to HEPN (MAE_28990 superfamily), RES domain, a potential RNase found in various toxin systems.


Pssm-ID: 436794  Cd Length: 131  Bit Score: 40.80  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556388750   26 LEVMRNWFFENFEDPANSCPYESREGGY--AYIYgGPYEASEELQAMFEGYVKFDYIQELVNDLQEQcyEWSGnsnniND 103
Cdd:pfam18870  25 MEFIMEGIRTEYGDAANELPYDSREGGYqgATTW-DTYDLLEDEIGLEADEDDDELLEDIASAIDDD--AWVE-----RD 96

                          90       100
                  ....*....|....*....|.
gi 556388750  104 WYDEDLYDAVTSSEQPFSKFV 124
Cdd:pfam18870  97 PYALSPDEALRYGWEQFCETV 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH