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Conserved domains on  [gi|553753964|ref|WP_023086742|]
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MULTISPECIES: heme biosynthesis protein HemY [Pseudomonas]

Protein Classification

heme biosynthesis protein HemY( domain architecture ID 11459652)

heme biosynthesis protein HemY similar to Escherichia coli HemY, is found in heme biosynthesis gene clusters and contains tetratricopeptide repeats (TPRs)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
92-399 2.54e-85

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


:

Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 262.92  E-value: 2.54e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  92 GLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTRAQLLINRGDYP 171
Cdd:COG3071   23 GLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAVLLTRAELLLDQGQAE 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 172 QARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEAGERglnegeta 251
Cdd:COG3071  103 QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRAYLGLLRQAARD-------- 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 252 LQPLTQRWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQLQAAEGWLKEH 331
Cdd:COG3071  175 AEALKALWKALPRAERRDPELAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLYGRLQGGDPAKQLKRAEKWLKKH 254
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 553753964 332 PNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEGLVLLD 399
Cdd:COG3071  255 PNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALAL 322
HemY_N pfam07219
HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of ...
30-132 1.09e-14

HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of bacterial HemY porphyrin biosynthesis proteins. This is a membrane protein involved in a late step of protoheme IX synthesis.


:

Pssm-ID: 429353 [Multi-domain]  Cd Length: 104  Bit Score: 69.46  E-value: 1.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   30 LIAYKSFRYESSLWSFLALLAVVWLLVVLVRLVLRLLGSSGRVVNPWSRYNRRRRVQMAEHSGLRDLGEGNWPQALRHLR 109
Cdd:pfam07219   1 LIVWGGYRIETSLWVAVLLLVLLFVLLYLLLRLLRLLLRLPGRVRRWRRRRRRRKARKALSEGLIALAEGDWAQAEKLAA 80
                          90       100
                  ....*....|....*....|...
gi 553753964  110 RAAEMGERPLMHYLGAARAANEL 132
Cdd:pfam07219  81 KAAKLLDAPLLNYLLAARAAQLQ 103
 
Name Accession Description Interval E-value
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
92-399 2.54e-85

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 262.92  E-value: 2.54e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  92 GLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTRAQLLINRGDYP 171
Cdd:COG3071   23 GLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAVLLTRAELLLDQGQAE 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 172 QARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEAGERglnegeta 251
Cdd:COG3071  103 QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRAYLGLLRQAARD-------- 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 252 LQPLTQRWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQLQAAEGWLKEH 331
Cdd:COG3071  175 AEALKALWKALPRAERRDPELAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLYGRLQGGDPAKQLKRAEKWLKKH 254
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 553753964 332 PNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEGLVLLD 399
Cdd:COG3071  255 PNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALAL 322
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
21-394 4.87e-82

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 256.06  E-value: 4.87e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   21 AISEQAGYVLIAYKSFRYESSLWSFLALLAVVWLLVVLVRLVLRLLGSSGRVVNPWSRYNRRRRVQMAEHSGLRDLGEGN 100
Cdd:TIGR00540   1 ALAGNTGYVLIVYPPYRIELSLNFFVLLLVLLFVVLYILLRLIRRVFRLPRRVRAWRSRRKQRRAQQATREGLIALFEGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  101 WPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTRAQLLINRGDYPQARNTLEEL 180
Cdd:TIGR00540  81 YSQAEKKATKAAEHSENPLLAYLLAARAAQQMGDEERRDRYLAEAAELAPNSELAVLLTRAELLLDQRDYEAALAALDSL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  181 HGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEAGERGlnegetaLQPLTQRWQ 260
Cdd:TIGR00540 161 QAQAPRHTAVLRLALRAYQRSGNWDALLKLLPALRKAKALSPEEAARLEQQAYIGLLDEAREED-------ADALKTWWK 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  261 NVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQLQAAEGWLKEHPNDPGLLLT 340
Cdd:TIGR00540 234 QLPRAERQEPELAVAAAEALIQLGDHDEAEKLIEEALKKEWDPELLRLYGRLQPGDPSPLIKRAEKWLKKHPDDALLLLA 313
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 553753964  341 LGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEG 394
Cdd:TIGR00540 314 LGRLCLRQQLWGKAQSYLEASLSLAPTEEAHLELAQLFEQLGDTEAAAQHYRKS 367
PRK10747 PRK10747
putative protoheme IX biogenesis protein; Provisional
81-403 1.10e-28

putative protoheme IX biogenesis protein; Provisional


Pssm-ID: 182695 [Multi-domain]  Cd Length: 398  Bit Score: 115.96  E-value: 1.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  81 RRRRVQMAEHSGLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTR 160
Cdd:PRK10747  80 KRRRARKQTEQALLKLAEGDYQQVEKLMTRNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELADNDQLPVEITR 159
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 161 AQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEA 240
Cdd:PRK10747 160 VRIQLARNENHAARHGVDKLLEVAPRHPEVLRLAEQAYIRTGAWSSLLDILPSMAKAHVGDEEHRAMLEQQAWIGLMDQA 239
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 241 GERGLNEGetalqpLTQRWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQ 320
Cdd:PRK10747 240 MADQGSEG------LKRWWKNQSRKTRHQVALQVAMAEHLIECDDHDTAQQIILDGLKRQYDERLVLLIPRLKTNNPEQL 313
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 321 LQAAEGWLKEHPNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEGLVLLDR 400
Cdd:PRK10747 314 EKVLRQQIKQHGDTPLLWSTLGQLLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTLQ 393

                 ...
gi 553753964 401 RTP 403
Cdd:PRK10747 394 NNP 396
HemY_N pfam07219
HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of ...
30-132 1.09e-14

HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of bacterial HemY porphyrin biosynthesis proteins. This is a membrane protein involved in a late step of protoheme IX synthesis.


Pssm-ID: 429353 [Multi-domain]  Cd Length: 104  Bit Score: 69.46  E-value: 1.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   30 LIAYKSFRYESSLWSFLALLAVVWLLVVLVRLVLRLLGSSGRVVNPWSRYNRRRRVQMAEHSGLRDLGEGNWPQALRHLR 109
Cdd:pfam07219   1 LIVWGGYRIETSLWVAVLLLVLLFVLLYLLLRLLRLLLRLPGRVRRWRRRRRRRKARKALSEGLIALAEGDWAQAEKLAA 80
                          90       100
                  ....*....|....*....|...
gi 553753964  110 RAAEMGERPLMHYLGAARAANEL 132
Cdd:pfam07219  81 KAAKLLDAPLLNYLLAARAAQLQ 103
TPR_19 pfam14559
Tetratricopeptide repeat;
133-197 1.48e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.79  E-value: 1.48e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 553753964  133 ERYDEADDLLNRAREREPD-AQLLVGLtrAQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQL 197
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDnAEARLGL--AEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
 
Name Accession Description Interval E-value
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
92-399 2.54e-85

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 262.92  E-value: 2.54e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  92 GLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTRAQLLINRGDYP 171
Cdd:COG3071   23 GLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAVLLTRAELLLDQGQAE 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 172 QARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEAGERglnegeta 251
Cdd:COG3071  103 QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRAYLGLLRQAARD-------- 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 252 LQPLTQRWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQLQAAEGWLKEH 331
Cdd:COG3071  175 AEALKALWKALPRAERRDPELAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLYGRLQGGDPAKQLKRAEKWLKKH 254
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 553753964 332 PNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEGLVLLD 399
Cdd:COG3071  255 PNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALAL 322
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
21-394 4.87e-82

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 256.06  E-value: 4.87e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   21 AISEQAGYVLIAYKSFRYESSLWSFLALLAVVWLLVVLVRLVLRLLGSSGRVVNPWSRYNRRRRVQMAEHSGLRDLGEGN 100
Cdd:TIGR00540   1 ALAGNTGYVLIVYPPYRIELSLNFFVLLLVLLFVVLYILLRLIRRVFRLPRRVRAWRSRRKQRRAQQATREGLIALFEGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  101 WPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTRAQLLINRGDYPQARNTLEEL 180
Cdd:TIGR00540  81 YSQAEKKATKAAEHSENPLLAYLLAARAAQQMGDEERRDRYLAEAAELAPNSELAVLLTRAELLLDQRDYEAALAALDSL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  181 HGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEAGERGlnegetaLQPLTQRWQ 260
Cdd:TIGR00540 161 QAQAPRHTAVLRLALRAYQRSGNWDALLKLLPALRKAKALSPEEAARLEQQAYIGLLDEAREED-------ADALKTWWK 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  261 NVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQLQAAEGWLKEHPNDPGLLLT 340
Cdd:TIGR00540 234 QLPRAERQEPELAVAAAEALIQLGDHDEAEKLIEEALKKEWDPELLRLYGRLQPGDPSPLIKRAEKWLKKHPDDALLLLA 313
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 553753964  341 LGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEG 394
Cdd:TIGR00540 314 LGRLCLRQQLWGKAQSYLEASLSLAPTEEAHLELAQLFEQLGDTEAAAQHYRKS 367
PRK10747 PRK10747
putative protoheme IX biogenesis protein; Provisional
81-403 1.10e-28

putative protoheme IX biogenesis protein; Provisional


Pssm-ID: 182695 [Multi-domain]  Cd Length: 398  Bit Score: 115.96  E-value: 1.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  81 RRRRVQMAEHSGLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLTR 160
Cdd:PRK10747  80 KRRRARKQTEQALLKLAEGDYQQVEKLMTRNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELADNDQLPVEITR 159
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 161 AQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEA 240
Cdd:PRK10747 160 VRIQLARNENHAARHGVDKLLEVAPRHPEVLRLAEQAYIRTGAWSSLLDILPSMAKAHVGDEEHRAMLEQQAWIGLMDQA 239
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 241 GERGLNEGetalqpLTQRWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQ 320
Cdd:PRK10747 240 MADQGSEG------LKRWWKNQSRKTRHQVALQVAMAEHLIECDDHDTAQQIILDGLKRQYDERLVLLIPRLKTNNPEQL 313
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 321 LQAAEGWLKEHPNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQRSAETCAELGRLLAQLGEVERSNQLFQEGLVLLDR 400
Cdd:PRK10747 314 EKVLRQQIKQHGDTPLLWSTLGQLLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTLQ 393

                 ...
gi 553753964 401 RTP 403
Cdd:PRK10747 394 NNP 396
HemY_N pfam07219
HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of ...
30-132 1.09e-14

HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of bacterial HemY porphyrin biosynthesis proteins. This is a membrane protein involved in a late step of protoheme IX synthesis.


Pssm-ID: 429353 [Multi-domain]  Cd Length: 104  Bit Score: 69.46  E-value: 1.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   30 LIAYKSFRYESSLWSFLALLAVVWLLVVLVRLVLRLLGSSGRVVNPWSRYNRRRRVQMAEHSGLRDLGEGNWPQALRHLR 109
Cdd:pfam07219   1 LIVWGGYRIETSLWVAVLLLVLLFVLLYLLLRLLRLLLRLPGRVRRWRRRRRRRKARKALSEGLIALAEGDWAQAEKLAA 80
                          90       100
                  ....*....|....*....|...
gi 553753964  110 RAAEMGERPLMHYLGAARAANEL 132
Cdd:pfam07219  81 KAAKLLDAPLLNYLLAARAAQLQ 103
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
76-389 5.36e-11

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 64.14  E-value: 5.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  76 WSRY---NRRRRVQMAEHSGLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDA 152
Cdd:COG3898   72 LSRYfrrRRRRKGYQALSRGLIAVAAGDGRLARRKAAKAERLLDRPPLTLLLEAQAAQLAGDREAARRAFEAMLEDPETR 151
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 153 QL-LVGLtrAQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKERVLKDSELRdlERR 231
Cdd:COG3898  152 FLgLRGL--MVEALRRGDTEAALALAEEALALAPKLPWAQDALLELQAAAGDWDGALATLDAALKAGLLDKDVAR--RRR 227
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 232 AwVASLQEAGERGLNEGETALQPLTQrwqnvpsALRADPAIV--AGHAAQLL-RLGAEEEAEEVLRHALKQGFDATLVQL 308
Cdd:COG3898  228 A-VLLTARARELEEGDPDEARELAIE-------ALKLAPDLVpaAVLAARLLiAQGKLRKAAKVLEKAWRAQPHPDLAAA 299
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 309 YGQVR-GRDPGKQLQAAEGWLKEHPNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQRSAETCaelgRLLAQLGEVERS 387
Cdd:COG3898  300 YAELRpGDSALDRLKRAETLAALNPDHPESRLALAEAALAAGDFGEARRALGPLLEERPTARVC----LLMAEIERGEHG 375

                 ..
gi 553753964 388 NQ 389
Cdd:COG3898  376 DD 377
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
99-395 1.56e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.18  E-value: 1.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDaQLLVGLTRAQLLINRGDYPQARNTLE 178
Cdd:TIGR02917 207 GNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPN-SPLAHYLKALVDFQKKNYEDARETLQ 285
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  179 ELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLpelrkERVLKDSELRDLERRAWVASLQEAGERGlnEGETALQPLTQR 258
Cdd:TIGR02917 286 DALKSAPEYLPALLLAGASEYQLGNLEQAYQYL-----NQILKYAPNSHQARRLLASIQLRLGRVD--EAIATLSPALGL 358
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  259 WQNVPSALRA------------------------DPAIVAGHAAQ-LLRL--GAEEEAEEVLRHALK---QGFDATLVQL 308
Cdd:TIGR02917 359 DPDDPAALSLlgeaylalgdfekaaeylakatelDPENAAARTQLgISKLsqGDPSEAIADLETAAQldpELGRADLLLI 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  309 YGQVRGRDPGKQLQAAEGWLKEHPNDPGLLLTLGRLCLINKLWGKAREYLEASLSFQR-SAETCAELGRLLAQLGEVERS 387
Cdd:TIGR02917 439 LSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPdFFPAAANLARIDIQEGNPDDA 518

                  ....*...
gi 553753964  388 NQLFQEGL 395
Cdd:TIGR02917 519 IQRFEKVL 526
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
98-207 1.62e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  98 EGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAqLLVGLTRAQLLINRGDYPQARNTL 177
Cdd:COG2956  123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC-ARALLLLAELYLEQGDYEEAIAAL 201
                         90       100       110
                 ....*....|....*....|....*....|
gi 553753964 178 EELHGLQPQHRTVLRLMQQLYVTQHDWQAL 207
Cdd:COG2956  202 ERALEQDPDYLPALPRLAELYEKLGDPEEA 231
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
70-216 6.25e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 6.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  70 GRVVNPWSRYNRRRRVQMAEHSGLRDLGE-----GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNR 144
Cdd:COG3914   92 GRYEEALALYRRALALNPDNAEALFNLGNlllalGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRR 171
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 553753964 145 AREREPD-AQLLVGLtrAQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRK 216
Cdd:COG3914  172 ALELDPDnAEALNNL--GNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAA 242
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
99-299 6.68e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 6.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPD-AQLLVGLtrAQLLINRGDYPQARNTL 177
Cdd:COG2956   90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEnAHAYCEL--AELYLEQGDYDEAIEAL 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 178 EELHGLQPQHRTVLRLMQQLYVTQHDWQALcvllpelrkERVLKDSELRDLERRAWVASLQEAGERgLNEGETALQPLTQ 257
Cdd:COG2956  168 EKALKLDPDCARALLLLAELYLEQGDYEEA---------IAALERALEQDPDYLPALPRLAELYEK-LGDPEEALELLRK 237
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 553753964 258 RWQNVPSalradPAIVAGHAAQLLRLGAEEEAEEVLRHALKQ 299
Cdd:COG2956  238 ALELDPS-----DDLLLALADLLERKEGLEAALALLERQLRR 274
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
92-362 4.53e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 4.53e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  92 GLRDLGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPD-AQLLVGLtrAQLLINRGDY 170
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDrAEALLEL--AQDYLKAGLL 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 171 PQARNTLEELHGLQPQHRTVLRLMQQLYVTQHDWQAlcvLLPELRKERVLKDSELRDLERRAWVASLQeagerglNEGET 250
Cdd:COG2956   93 DRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK---AIEVLERLLKLGPENAHAYCELAELYLEQ-------GDYDE 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 251 ALQPLTQrwqnvpsALRADPAIVAGHAAQ---LLRLGAEEEAEEVLRHALKQGFDAT-----LVQLYGQVrgRDPGKQLQ 322
Cdd:COG2956  163 AIEALEK-------ALKLDPDCARALLLLaelYLEQGDYEEAIAALERALEQDPDYLpalprLAELYEKL--GDPEEALE 233
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 553753964 323 AAEGWLKEHPNDPGLLLTLGRLCLINKlWGKAREYLEASL 362
Cdd:COG2956  234 LLRKALELDPSDDLLLALADLLERKEG-LEAALALLERQL 272
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
98-206 4.95e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 4.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  98 EGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVgLTRAQLLINRGDYPQARNTL 177
Cdd:COG4783   17 AGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEAR-LNLGLALLKAGDYDEALALL 95
                         90       100
                 ....*....|....*....|....*....
gi 553753964 178 EELHGLQPQHRTVLRLMQQLYVTQHDWQA 206
Cdd:COG4783   96 EKALKLDPEHPEAYLRLARAYRALGRPDE 124
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
103-206 5.34e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 5.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 103 QALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPD-AQLLVGLtrAQLLINRGDYPQARNTLEELH 181
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDnADALLDL--AEALLAAGDTEEAEELLERAL 78
                         90       100
                 ....*....|....*....|....*
gi 553753964 182 GLQPQHRTVLRLMQQLYVTQHDWQA 206
Cdd:COG4235   79 ALDPDNPEALYLLGLAAFQQGDYAE 103
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
99-291 1.86e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.77  E-value: 1.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREP-DAQLLVGLtrAQLLINRGDYPQARNTL 177
Cdd:COG0457   56 GRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPdDAEALYNL--GLALLELGRYDEAIEAY 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 178 EELHGLQPQHRTVLRLMQQLYVTQHDWQAlcvLLPELRKERVLKDSELRDLERRAWVASLQEAGERGLNEGETALQPLTQ 257
Cdd:COG0457  134 ERALELDPDDADALYNLGIALEKLGRYEE---ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKK 210
                        170       180       190
                 ....*....|....*....|....*....|....
gi 553753964 258 RWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEE 291
Cdd:COG0457  211 LAILTLAALAELLLLALALLLALRLAALALYQYR 244
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
96-217 5.15e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.72  E-value: 5.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  96 LGEGNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAqLLVGLTRAQLLINRGDYPQARN 175
Cdd:COG2956  155 LEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDY-LPALPRLAELYEKLGDPEEALE 233
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 553753964 176 TLEELHGLQPQHRTVLRLMQQLYVTQHDWQALCVLLPELRKE 217
Cdd:COG2956  234 LLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
99-328 8.30e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 8.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREP-DAQLLVGLtrAQLLINRGDYPQARNTL 177
Cdd:COG0457   22 GRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPdDAEALNNL--GLALQALGRYEEALEDY 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 178 EELHGLQPQHRTVLRLMQQLYVTQHDWQAlcvLLPELRKERVLKDSELRDLERRAWVAslqeageRGLNEGETALQPLTQ 257
Cdd:COG0457  100 DKALELDPDDAEALYNLGLALLELGRYDE---AIEAYERALELDPDDADALYNLGIAL-------EKLGRYEEALELLEK 169
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 553753964 258 RWQNVPSALRADPAIVAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLYGQVRGRDPGKQLQAAEGWL 328
Cdd:COG0457  170 LEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
99-197 1.99e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 1.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDAQLLVGLtRAQLLINRGDYPQARNTLE 178
Cdd:COG4235   31 GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYL-LGLAAFQQGDYAEAIAAWQ 109
                         90
                 ....*....|....*....
gi 553753964 179 ELHGLQPQHRTVLRLMQQL 197
Cdd:COG4235  110 KLLALLPADAPARLLEASI 128
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
99-334 2.58e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 2.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964   99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDA-QLLVGLTRAQLLinRGDYPQARNTL 177
Cdd:TIGR02917 547 GNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSpEAWLMLGRAQLA--AGDLNKAVSSF 624
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  178 EELHGLQPQHRTVLRLMQQLYVTQHDWQALcvlLPELRKERVLKdSELRDLERRAWVASLQEagerglNEGETALQPLTQ 257
Cdd:TIGR02917 625 KKLLALQPDSALALLLLADAYAVMKNYAKA---ITSLKRALELK-PDNTEAQIGLAQLLLAA------KRTESAKKIAKS 694
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 553753964  258 RWQNVPSAlradPAIVAGHAAQLLRLGAEEEAEEVLRHALK-QGFDATLVQLYG-QVRGRDPGKQLQAAEGWLKEHPND 334
Cdd:TIGR02917 695 LQKQHPKA----ALGFELEGDLYLRQKDYPAAIQAYRKALKrAPSSQNAIKLHRaLLASGNTAEAVKTLEAWLKTHPND 769
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
99-187 4.27e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 4.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDLLNRAREREPDaQLLVGLTRAQLLINRGDYPQARNTLE 178
Cdd:COG4783   52 GDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPE-HPEAYLRLARAYRALGRPDEAIAALE 130

                 ....*....
gi 553753964 179 ELHGLQPQH 187
Cdd:COG4783  131 KALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
99-185 6.92e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 6.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  99 GNWPQALRHLRRAAEMGERPLMHYLGAARAANELERYDEADDlLNRAREREPDaQLLVGLTRAQLLINRGDYPQARNTLE 178
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPN-NAEALLNLAELLLELGDYDEALAYLE 83

                 ....*..
gi 553753964 179 ELHGLQP 185
Cdd:COG3063   84 RALELDP 90
TPR_19 pfam14559
Tetratricopeptide repeat;
133-197 1.48e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.79  E-value: 1.48e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 553753964  133 ERYDEADDLLNRAREREPD-AQLLVGLtrAQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQL 197
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDnAEARLGL--AEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
122-206 2.80e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 2.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 122 YLGAARAANELERYDEADDLLNRAREREPDaQLLVGLTRAQLLINRGDYPQARNTLEELHGLQPQHRTVLRLMQQLYVTQ 201
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPD-NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                 ....*
gi 553753964 202 HDWQA 206
Cdd:COG4783   86 GDYDE 90
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
193-397 4.30e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.21  E-value: 4.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 193 LMQQLYVTQHDWQALCVLLPELRKERVLKDSELRDLERRAWVASLQEAgerglnEGETALQPLTQRWQNVPSALRADPAI 272
Cdd:COG3914    7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEA------AAAALLALAAGEAAAAAAALLLLAAL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964 273 VAGHAAQLLRLGAEEEAEEVLRHALKQGFDATLVQLY-GQV--RGRDPGKQLQAAEGWLKEHPNDPGLLLTLGRLCLINK 349
Cdd:COG3914   81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNlGNLllALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 553753964 350 LWGKAREYLEASLSFQ-RSAETCAELGRLLAQLGEVERSNQLFQEGLVL 397
Cdd:COG3914  161 RLEEAIAALRRALELDpDNAEALNNLGNALQDLGRLEEAIAAYRRALEL 209
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
96-217 5.02e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 38.32  E-value: 5.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553753964  96 LGEGNWPQALRHLRRAAE--MGERP-LMhyLGAARAANELERYDEADDLLNRAREREP-----DAQLLVGLTRAQLlinr 167
Cdd:COG4700  100 LELGRYDEAIELYEEALTgiFADDPhIL--LGLAQALFELGRYAEALETLEKLIAKNPdfkssDAHLLYARALEAL---- 173
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 553753964 168 GDYPQARNTLEELHGLQPQHRTVLRLmQQLYVTQHDWQALCVLLPELRKE 217
Cdd:COG4700  174 GDLEAAEAELEALARRYSGPEARYRY-AKFLARQGRTAEAKELLEEILDE 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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