NCBI Conserved Domain Search

Conserved domains on [gi|550714244|ref|WP_022647133|]

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MULTISPECIES: ABC transporter ATP-binding protein [Enterobacter]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11418519)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including dipeptides and oligopeptides

CATH: 3.40.50.300

Gene Ontology: GO:0042626|GO:0140359|GO:0016887

PubMed: 25750732|24638992

SCOP: 4003976

TCDB: 3.A.1

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

12-325

0e+00

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 506.90 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArIVSGEMHFRRHDLRKLSPRE 89
Cdd:COG0444    1 LLEVRNLKVYFPtrRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG-ITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRV 169
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIF 249
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 250 ADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGTGHQVACFRV 325
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRVACHLY 315

Name

Accession

Description

Interval

E-value

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

12-325

0e+00

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 506.90 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArIVSGEMHFRRHDLRKLSPRE 89
Cdd:COG0444    1 LLEVRNLKVYFPtrRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG-ITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRV 169
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIF 249
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 250 ADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGTGHQVACFRV 325
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRVACHLY 315

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

9-328

5.32e-136

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 389.47 E-value: 5.32e-136

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFaGSP---VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIvSGEMHFRRHDLRKL 85
Cdd:PRK09473   9 ADALLDVKDLRVTF-STPdgdVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRI-GGSATFNGREILNL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGM 165
Cdd:PRK09473  87 PEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFSGGM 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:PRK09473 167 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNA 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 246 EAIFADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEkPPLTMLGTGHQVACFRV 325
Cdd:PRK09473 247 RDVFYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSA-PPLEEFGPGRLRACFKP 325


                 ...
gi 550714244 326 PLE 328
Cdd:PRK09473 326 VEE 328

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

12-243

2.25e-107

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 312.90 E-value: 2.25e-107

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLRKLSPRE 89
Cdd:cd03257    1 LLEVKNLSVSFPtgGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLL----KPTSGSIIFDGKDLLKLSRRL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALqILEKVQIPAAEMRLKVYPHQLSGGMRQRV 169
Cdd:cd03257   77 -RKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAV-LLLLVGVGLPEEVLNRYPHELSGGQRQRV 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03257  155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

nickel_nikD

TIGR02770

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...

32-262

2.83e-83

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 251.90 E-value: 2.83e-83

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   32 DISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSpreyanLRGSELAMIFQEPMTSLNP 111
Cdd:TIGR02770   4 DLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPLS------IRGRHIATIMQNPRTAFNP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  112 AFTLGDQLSEAVMRHQTLSrAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTAL 191
Cdd:TIGR02770  78 LFTMGNHAIETLRSLGKLS-KQARALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244  192 DVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGLMG 262
Cdd:TIGR02770 157 DVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLS 227

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

30-189

1.74e-36

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 128.53 E-value: 1.74e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPReyanLRGSELAMIFQEPmtSL 109
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPT----EGTILLDGQDLTDDERK----SLRKEIGYVFQDP--QL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  110 NPAFTLGDQLSEAVmRHQTLSRAEAMTVALQILEKVQIP-AAEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPT 188
Cdd:pfam00005  71 FPRLTVRENLRLGL-LLKGLSKREKDARAEEALEKLGLGdLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149


                  .
gi 550714244  189 T 189
Cdd:pfam00005 150 A 150

GguA

NF040905

sugar ABC transporter ATP-binding protein;

12-241

2.40e-21

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 94.47 E-value: 2.40e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAriVSGEMHFRRhdlrklSPREYA 91
Cdd:NF040905   1 ILEMRGITKTFPG--VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGS--YEGEILFDG------EVCRFK 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGSE---LAMIFQE----PMTSLNPAFTLGDQLSE--AVMRHQTLSRAEAMtvalqiLEKVqipaaemRLKVYPHQLS 162
Cdd:NF040905  71 DIRDSEalgIVIIHQElaliPYLSIAENIFLGNERAKrgVIDWNETNRRAREL------LAKV-------GLDESPDTLV 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 G----GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:NF040905 138 TdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216


                 ...
gi 550714244 239 VVE 241
Cdd:NF040905 217 TIE 219

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

22-226

3.11e-19

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 84.21 E-value: 3.11e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  22 FAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVsgemhfRRHdlrklspreyanlRGSELAMI 101
Cdd:NF040873   2 YGGRPV--LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV------RRA-------------GGARVAYV 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 102 FQEpmTSLNPAF--TLGDQLSEAVMRHQTLSR---AEAMTVALQILEKVQIPA-AEMRLkvypHQLSGGMRQRVMIAMAL 175
Cdd:NF040873  61 PQR--SEVPDSLplTVRDLVAMGRWARRGLWRrltRDDRAAVDDALERVGLADlAGRQL----GELSGGQRQRALLAQGL 134

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 550714244 176 INHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAE 226
Cdd:NF040873 135 AQEADLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRR 184

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

27-248

2.20e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 63.99 E-value: 2.20e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSitslalMGLLPASariVSGEMHFRRhdlrklsPREY----ANLRGSELAMIF 102
Cdd:NF000106  26 VKAVDGVDLDVREGTVLGVLGP*GAA**------RGALPAH---V*GPDAGRR-------PWRF*twcANRRALRRTIG* 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 103 QEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVyphQLSGGMRQRVMIAMALINHPKLL 182
Cdd:NF000106  90 HRPVR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAA---KYSGGMRRRLDLAASMIGRPAVL 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 183 IADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:NF000106 167 YLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

12-250

8.59e-09

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 57.06 E-value: 8.59e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLpASARIV--------SGEMHFRRHdLR 83
Cdd:NF033858   1 VARLEGVSHRYGK--TVALDDVSLDIPAGCMVGLIGPDGVGKS----SLLSLI-AGARKIqqgrvevlGGDMADARH-RR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  84 KLSPReyanlrgselamIfqepmtslnpAFT---LGDQLseavmrHQTLSraeamtvalqILEKVQ-------IPAAEMR 153
Cdd:NF033858  73 AVCPR------------I----------AYMpqgLGKNL------YPTLS----------VFENLDffgrlfgQDAAERR 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 154 LKV---------YPH------QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEET-GTAVLmi 217
Cdd:NF033858 115 RRIdellratglAPFadrpagKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVL-- 192

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 550714244 218 thdlgvVA----EVAQQ---VAVMYAGQVVEQGSVEAIFA 250
Cdd:NF033858 193 ------VAtaymEEAERfdwLVAMDAGRVLATGTPAELLA 226

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

5-192

6.46e-08

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 53.98 E-value: 6.46e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   5 PFKDSTPVLRLQNLNVKFaGSPVSVlEDISLAVRAGETLALVGESGCGKSITSLALMGLLPAS---ARIVSGEMHFRRHD 81
Cdd:NF033858 259 ADDDDEPAIEARGLTMRF-GDFTAV-DHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASegeAWLFGQPVDAGDIA 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  82 LRK--------------LSPREyaNLrgsEL-AMIFQEPmtslnpaftlGDQLSEAVmrHQTLSRAEamtvalqiLEKVq 146
Cdd:NF033858 337 TRRrvgymsqafslygeLTVRQ--NL---ELhARLFHLP----------AAEIAARV--AEMLERFD--------LADV- 390

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 550714244 147 ipaaemrLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALD 192
Cdd:NF033858 391 -------ADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429

GguA

NF040905

sugar ABC transporter ATP-binding protein;

6-248

7.07e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 7.07e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   6 FKDSTP-----VLRLQNLNVkfaGSPVS----VLEDISLAVRAGETLALVGESGCGKsiTSLAlMGLLPAS-ARIVSGE- 74
Cdd:NF040905 246 YPERTPkigevVFEVKNWTV---YHPLHperkVVDDVSLNVRRGEIVGIAGLMGAGR--TELA-MSVFGRSyGRNISGTv 319

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  75 -MHFRRHDLRklSPRE-------YANLRGSELAMIFQEPMTSLNPAFTLGdqlseAVMRHQTLSRAEAMTVALQILEKVQ 146
Cdd:NF040905 320 fKDGKEVDVS--TVSDaidaglaYVTEDRKGYGLNLIDDIKRNITLANLG-----KVSRRGVIDENEEIKVAEEYRKKMN 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 147 IPAAEMRLKVypHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAE 226
Cdd:NF040905 393 IKTPSVFQKV--GNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLG 469

                        250       260
                 ....*....|....*....|....*..
gi 550714244 227 VAQQVAVMYAGQVV-----EQGSVEAI 248
Cdd:NF040905 470 MCDRIYVMNEGRITgelprEEASQERI 496

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

40-226

2.19e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 46.60 E-value: 2.19e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    40 GETLALVGESGCGKSITSLALMGLLPASAR---IVSGEMHFRRHDLRKLspreyanlrgselamifqepmtslnpaftlg 116
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGgviYIDGEDILEEVLDQLL------------------------------- 50

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   117 dqlseavmrhqtlsraeamtvalqilekvqipaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQ 196
Cdd:smart00382  51 ----------------------------------LIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQE 96

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 550714244   197 AQILALLNT-----LKEETGTAVLMITHDLGVVAE 226
Cdd:smart00382  97 ALLLLLEELrllllLKSEKNLTVILTTNDEKDLGP 131

Name

Accession

Description

Interval

E-value

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

12-325

0e+00

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 506.90 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArIVSGEMHFRRHDLRKLSPRE 89
Cdd:COG0444    1 LLEVRNLKVYFPtrRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG-ITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRV 169
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIF 249
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 250 ADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGTGHQVACFRV 325
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRVACHLY 315

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

8-270

1.32e-144

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 418.70 E-value: 1.32e-144

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAGS--PVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKL 85
Cdd:COG4172    2 MSMPLLSVEDLSVAFGQGggTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPSGSILFDGQDLLGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGM 165
Cdd:COG4172   82 SERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSGGQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:COG4172  162 RQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPT 241

                        250       260
                 ....*....|....*....|....*
gi 550714244 246 EAIFADPQHPYTIGLMGSIPSLGVR 270
Cdd:COG4172  242 AELFAAPQHPYTRKLLAAEPRGDPR 266

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

9-328

5.32e-136

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 389.47 E-value: 5.32e-136

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFaGSP---VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIvSGEMHFRRHDLRKL 85
Cdd:PRK09473   9 ADALLDVKDLRVTF-STPdgdVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRI-GGSATFNGREILNL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGM 165
Cdd:PRK09473  87 PEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFSGGM 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:PRK09473 167 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNA 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 246 EAIFADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEkPPLTMLGTGHQVACFRV 325
Cdd:PRK09473 247 RDVFYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSA-PPLEEFGPGRLRACFKP 325


                 ...
gi 550714244 326 PLE 328
Cdd:PRK09473 326 VEE 328

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

8-325

3.07e-118

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 344.41 E-value: 3.07e-118

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKF---------AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFR 78
Cdd:COG4608    3 MAEPLLEVRDLKKHFpvrgglfgrTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPT----SGEILFD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  79 RHDLRKLSPREYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLkvYP 158
Cdd:COG4608   79 GQDITGLSGRELRPLR-RRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADR--YP 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:COG4608  156 HEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGK 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 239 VVEQGSVEAIFADPQHPYTIGLMGSIPSLGV-RKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGTG 317
Cdd:COG4608  236 IVEIAPRDELYARPLHPYTQALLSAVPVPDPeRRRERIVLEGDVPSPLNPPSGCRFHTRCPYAQDRCATEEPPLREVGPG 315


                 ....*...
gi 550714244 318 HQVACFRV 325
Cdd:COG4608  316 HQVACHLA 323

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

12-322

4.27e-116

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 338.64 E-value: 4.27e-116

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSPRE 89
Cdd:PRK11022   3 LLNVDKLSVHFGdeSAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRV 169
Cdd:PRK11022  83 RRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQRV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIF 249
Cdd:PRK11022 163 MIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIF 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 250 ADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGtGHQVAC 322
Cdd:PRK11022 243 RAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLA-GRQSKC 314

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

12-243

2.25e-107

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 312.90 E-value: 2.25e-107

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLRKLSPRE 89
Cdd:cd03257    1 LLEVKNLSVSFPtgGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLL----KPTSGSIIFDGKDLLKLSRRL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALqILEKVQIPAAEMRLKVYPHQLSGGMRQRV 169
Cdd:cd03257   77 -RKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAV-LLLLVGVGLPEEVLNRYPHELSGGQRQRV 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03257  155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

7-267

4.74e-104

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 314.53 E-value: 4.74e-104

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   7 KDSTPVLRLQNLNVKFAGSP---VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLR 83
Cdd:COG1123  255 AAAEPLLEVRNLSKRYPVRGkggVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPT----SGSILFDGKDLT 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  84 KLSPREYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLkvYPHQLSG 163
Cdd:COG1123  331 KLSRRSLRELR-RRVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADR--YPHELSG 407

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:COG1123  408 GQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDG 487

                        250       260
                 ....*....|....*....|....
gi 550714244 244 SVEAIFADPQHPYTIGLMGSIPSL 267
Cdd:COG1123  488 PTEEVFANPQHPYTRALLAAVPSL 511

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

11-322

2.00e-102

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 304.14 E-value: 2.00e-102

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSPR 88
Cdd:COG4170    2 PLLDIRNLTIEIdtPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHVTADRFRWNGIDLLKLSPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAV----------MRHQTLSRAeamtvALQILEKVQIPAAEMRLKVYP 158
Cdd:COG4170   82 ERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIpswtfkgkwwQRFKWRKKR-----AIELLHRVGIKDHKDIMNSYP 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:COG4170  157 HELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQ 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 239 VVEQGSVEAIFADPQHPYTIGLMGSIPSLGV---RKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRChAEKPPLTMLg 315
Cdd:COG4170  237 TVESGPTEQILKSPHHPYTKALLRSMPDFRQplpHKSRLNTLPGSIPPLQHLPIGCRLGPRCPYAQKKC-VETPRLRKI- 314


                 ....*..
gi 550714244 316 TGHQVAC 322
Cdd:COG4170  315 KGHEFAC 321

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

10-280

1.35e-101

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 308.37 E-value: 1.35e-101

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIvSGEMHFRRHDLRKLSPRe 89
Cdd:COG1123    2 TPLLEVRDLSVRYPGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGRI-SGEVLLDGRDLLELSEA- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanLRGSELAMIFQEPMTSLNPAfTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMRQRV 169
Cdd:COG1123   80 ---LRGRRIGMVFQDPMTQLNPV-TVGDQIAEA-LENLGLSRAEARARVLELLEAVGLER---RLDRYPHQLSGGQRQRV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIF 249
Cdd:COG1123  152 AIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEIL 231

                        250       260       270
                 ....*....|....*....|....*....|.
gi 550714244 250 ADPQhpytigLMGSIPSLGVRKGQLSTIPGS 280
Cdd:COG1123  232 AAPQ------ALAAVPRLGAARGRAAPAAAA 256

PRK10261

glutathione transporter ATP-binding protein; Provisional

8-289

6.22e-98

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 302.16 E-value: 6.22e-98

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLP-ASARIVSGEMHFRRH---- 80
Cdd:PRK10261   8 DARDVLAVENLNIAFMqeQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEqAGGLVQCDKMLLRRRsrqv 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  81 -DLRKLSPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPH 159
Cdd:PRK10261  88 iELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRYPH 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:PRK10261 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEA 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 550714244 240 VEQGSVEAIFADPQHPYTIGLMGSIPSLGVRKGQlsTIPGSVPLPeSMPQ 289
Cdd:PRK10261 248 VETGSVEQIFHAPQHPYTRALLAAVPQLGAMKGL--DYPRRFPLI-SLEH 294

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

8-325

2.45e-94

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 283.39 E-value: 2.45e-94

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLN----VK---FAGSP-VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRR 79
Cdd:PRK11308   1 SQQPLLQAIDLKkhypVKrglFKPERlVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPT----GGELYYQG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  80 HDLRKLSPREYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRlkvYP 158
Cdd:PRK11308  77 QDLLKADPEAQKLLR-QKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLrPEHYDR---YP 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:PRK11308 153 HMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGR 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 239 VVEQGSVEAIFADPQHPYTIGLMGSIPSL--GVRKGQLsTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGt 316
Cdd:PRK11308 233 CVEKGTKEQIFNNPRHPYTQALLSATPRLnpDDRRERI-KLTGELPSPLNPPPGCAFNARCPRAFGRCRQEQPQLRDYD- 310


                 ....*....
gi 550714244 317 GHQVACFRV 325
Cdd:PRK11308 311 GRLVACFAV 319

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

9-266

3.14e-93

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 287.37 E-value: 3.14e-93

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARI-VSGEMHFRRHDLRKL 85
Cdd:PRK15134   2 TQPLLAIENLSVAFrqQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVVyPSGDIRFHGESLLHA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGM 165
Cdd:PRK15134  82 SEQTLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGGE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:PRK15134 162 RQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRA 241

                        250       260
                 ....*....|....*....|.
gi 550714244 246 EAIFADPQHPYTIGLMGSIPS 266
Cdd:PRK15134 242 ATLFSAPTHPYTQKLLNSEPS 262

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

8-267

8.73e-88

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 273.10 E-value: 8.73e-88

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAG---------SPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivsGEMHFR 78
Cdd:COG4172  271 DAPPLLEARDLKVWFPIkrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPSE-----GEIRFD 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  79 RHDLRKLSPREYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQT-LSRAEAMTVALQILEKVQIPAaEMRLKvY 157
Cdd:COG4172  346 GQDLDGLSRRALRPLR-RRMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGPgLSAAERRARVAEALEEVGLDP-AARHR-Y 422

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:COG4172  423 PHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDG 502

                        250       260       270
                 ....*....|....*....|....*....|
gi 550714244 238 QVVEQGSVEAIFADPQHPYTIGLMGSIPSL 267
Cdd:COG4172  503 KVVEQGPTEQVFDAPQHPYTRALLAAAPLL 532

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

31-325

7.98e-86

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 261.95 E-value: 7.98e-86

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  31 EDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYANLRgSELAMIFQEPMTSLN 110
Cdd:PRK15079  38 DGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKAT----DGEVAWLGKDLLGMKDDEWRAVR-SDIQMIFQDPLASLN 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 111 PAFTLGDQLSEAVMRHQ-TLSRAEAMtvalqilEKVQipaaEMRLKV---------YPHQLSGGMRQRVMIAMALINHPK 180
Cdd:PRK15079 113 PRMTIGEIIAEPLRTYHpKLSRQEVK-------DRVK----AMMLKVgllpnlinrYPHEFSGGQCQRIGIARALILEPK 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 181 LLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGL 260
Cdd:PRK15079 182 LIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTKAL 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 261 MGSIPSLGVRKGQLSTI---PGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTmlGT-GHQVACFRV 325
Cdd:PRK15079 262 MSAVPIPDPDLERNKTIqllEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLE--GSfRHAVSCLKV 328

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

13-270

1.12e-84

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 255.88 E-value: 1.12e-84

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSP--VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREY 90
Cdd:COG1124    2 LEVRNLSVSYGQGGrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPW----SGEVTFDGRPVTRRRRKAF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 AnlrgSELAMIFQEPMTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALqiLEKVQIPAAEMRLkvYPHQLSGGMRQRVM 170
Cdd:COG1124   78 R----RRVQMVFQDPYASLHPRHTVDRILAEP-LRIHGLPDREERIAEL--LEQVGLPPSFLDR--YPHQLSGGQRQRVA 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:COG1124  149 IARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLA 228

                        250       260
                 ....*....|....*....|
gi 550714244 251 DPQHPYTIGLMGSIPSLGVR 270
Cdd:COG1124  229 GPKHPYTRELLAASLAFERA 248

nickel_nikD

TIGR02770

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...

32-262

2.83e-83

Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 251.90 E-value: 2.83e-83

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   32 DISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSpreyanLRGSELAMIFQEPMTSLNP 111
Cdd:TIGR02770   4 DLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPLS------IRGRHIATIMQNPRTAFNP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  112 AFTLGDQLSEAVMRHQTLSrAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTAL 191
Cdd:TIGR02770  78 LFTMGNHAIETLRSLGKLS-KQARALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244  192 DVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGLMG 262
Cdd:TIGR02770 157 DVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLS 227

PRK15093

peptide ABC transporter ATP-binding protein SapD;

11-322

3.01e-80

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 247.41 E-value: 3.01e-80

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSPR 88
Cdd:PRK15093   2 PLLDIRNLTIEFktSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSR-----AEAMTVALQILEKVQIPAAEMRLKVYPHQLSG 163
Cdd:PRK15093  82 ERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPGWTYKGRwwqrfGWRKRRAIELLHRVGIKDHKDAMRSFPYELTE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:PRK15093 162 GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 244 SVEAIFADPQHPYTIGLMGSIPSLGV---RKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRChAEKPPLTMLGTgHQV 320
Cdd:PRK15093 242 PSKELVTTPHHPYTQALIRAIPDFGSampHKSRLNTLPGAIPLLEHLPIGCRLGPRCPYAQREC-IETPRLTGAKN-HLY 319


                 ..
gi 550714244 321 AC 322
Cdd:PRK15093 320 AC 321

PhnK

COG4107

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...

7-264

8.25e-67

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];

Pssm-ID: 443283 [Multi-domain] Cd Length: 262 Bit Score: 210.82 E-value: 8.25e-67

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   7 KDSTPVLRLQNLNVKFAGSPVSV--LEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRR----- 79
Cdd:COG4107    3 NEEQPLLSVRGLSKRYGPGCGTVvaCRDVSFDLYPGEVLGIVGESGSGKS----TLLKCLYFDLAPTSGSVYYRDrdggp 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  80 HDLRKLSPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVM----RHQTLSRAEAmtvaLQILEKVQIPAAemRLK 155
Cdd:COG4107   79 RDLFALSEAERRRLRRTDWGMVYQNPRDGLRMDVSAGGNIAERLMaageRHYGDIRARA----LEWLERVEIPLE--RID 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 VYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:COG4107  153 DLPRTFSGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRTMVMK 232

                        250       260
                 ....*....|....*....|....*....
gi 550714244 236 AGQVVEQGSVEAIFADPQHPYTIGLMGSI 264
Cdd:COG4107  233 NGRVVESGLTDQVLEDPQHPYTQLLVSSV 261

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

12-257

9.87e-65

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 205.32 E-value: 9.87e-65

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKfagSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFrrhDLRKLSPreyA 91
Cdd:PRK10418   4 QIELRNIALQ---AAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGVRQTAGRVLL---DGKPVAP---C 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVmrhQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRVMI 171
Cdd:PRK10418  75 ALRGRKIATIMQNPRSAFNPLHTMHTHARETC---LALGKPADDATLTAALEAVGLENAARVLKLYPFEMSGGMLQRMMI 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 172 AMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PRK10418 152 ALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNA 231


                 ....*.
gi 550714244 252 PQHPYT 257
Cdd:PRK10418 232 PKHAVT 237

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

8-261

1.02e-59

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 200.32 E-value: 1.02e-59

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAG---------SPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivsGEMHFR 78
Cdd:PRK15134 271 PASPLLDVEQLQVAFPIrkgilkrtvDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQ-----GEIWFD 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  79 RHDLRKLSPREYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQ-TLSRAEAMTVALQILEKVQI-PAAEMRlkv 156
Cdd:PRK15134 346 GQPLHNLNRRQLLPVR-HRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHQpTLSAAQREQQVIAVMEEVGLdPETRHR--- 421

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 157 YPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYA 236
Cdd:PRK15134 422 YPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQ 501

                        250       260
                 ....*....|....*....|....*
gi 550714244 237 GQVVEQGSVEAIFADPQHPYTIGLM 261
Cdd:PRK15134 502 GEVVEQGDCERVFAAPQQEYTRQLL 526

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

10-242

1.86e-58

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 187.94 E-value: 1.86e-58

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLpasARIVSGEMHFRRHDLRKLSP 87
Cdd:COG1136    2 SPLLELRNLTKSYGtgEGEVTALRGVSLSIEAGEFVAIVGPSGSGKS-TLLNILGGL---DRPTSGEVLIDGQDISSLSE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANLRGSELAMIFQEPmtSLNPAFTLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMRQ 167
Cdd:COG1136   78 RELARLRRRHIGFVFQFF--NLLPELTALENV-ALPLLLAGVSRKERRERARELLERVGLGD---RLDHRPSQLSGGQQQ 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLgVVAEVAQQVAVMYAGQVVEQ 242
Cdd:COG1136  152 RVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRIVSD 225

SapF

COG4167

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

10-263

1.23e-56

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 184.66 E-value: 1.23e-56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSP-------VSVLEDISLAVRAGETLALVGESGCGKSitSLALM--GLLPASarivSGEMHFRRH 80
Cdd:COG4167    2 SALLEVRNLSKTFKYRTglfrrqqFEAVKPVSFTLEAGQTLAIIGENGSGKS--TLAKMlaGIIEPT----SGEILINGH 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  81 dlrKLSPREYANlRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMrlKVYPHQ 160
Cdd:COG4167   76 ---KLEYGDYKY-RCKHIRMIFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLLPEHA--NFYPHM 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:COG4167  150 LSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVV 229

                        250       260
                 ....*....|....*....|...
gi 550714244 241 EQGSVEAIFADPQHPYTIGLMGS 263
Cdd:COG4167  230 EYGKTAEVFANPQHEVTKRLIES 252

PRK10261

glutathione transporter ATP-binding protein; Provisional

8-321

7.74e-56

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 191.61 E-value: 7.74e-56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKF---------AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivsGEMHFR 78
Cdd:PRK10261 309 DGEPILQVRNLVTRFplrsgllnrVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQG----GEIIFN 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  79 RHDLRKLSPREYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRlkvY 157
Cdd:PRK10261 385 GQRIDTLSPGKLQALR-RDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLlPEHAWR---Y 460

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:PRK10261 461 PHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLG 540

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 238 QVVEQGSVEAIFADPQHPYTIGLMGSIP--SLGVRKGQlstipgSVPLPESMPQGCRFATRCPFAQtrchaekpPLTMLG 315
Cdd:PRK10261 541 QIVEIGPRRAVFENPQHPYTRKLMAAVPvaDPSRQRPQ------RVLLSDDLPSNIHLRGEEVAAV--------SLQCVG 606


                 ....*.
gi 550714244 316 TGHQVA 321
Cdd:PRK10261 607 PGHYVA 612

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

13-239

4.24e-55

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 179.22 E-value: 4.24e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGS--PVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLpasARIVSGEMHFRRHDLRKLSPREY 90
Cdd:cd03255    1 IELKNLSKTYGGGgeKVQALKGVSLSIEKGEFVAIVGPSGSGKS-TLLNILGGL---DRPTSGEVRVDGTDISKLSEKEL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRGSELAMIFQEPmtSLNPAFTLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMRQRVM 170
Cdd:cd03255   77 AAFRRRHIGFVFQSF--NLLPDLTALENV-ELPLLLAGVPKKERRERAEELLERVGLGD---RLNHYPSELSGGQQQRVA 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLgVVAEVAQQVAVMYAGQV 239
Cdd:cd03255  151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGKI 218

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

8-264

1.00e-54

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 179.35 E-value: 1.00e-54

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAgsPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivsGEMHFR-----RHDL 82
Cdd:PRK11701   2 MDQPLLSVRGLTKLYG--PRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDA----GEVHYRmrdgqLRDL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  83 RKLSPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVM----RHQTLSRAEAmtvaLQILEKVQIPAAemRLKVYP 158
Cdd:PRK11701  76 YALSEAERRRLLRTEWGFVHQHPRDGLRMQVSAGGNIGERLMavgaRHYGDIRATA----GDWLERVEIDAA--RIDDLP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:PRK11701 150 TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229

                        250       260
                 ....*....|....*....|....*.
gi 550714244 239 VVEQGSVEAIFADPQHPYTIGLMGSI 264
Cdd:PRK11701 230 VVESGLTDQVLDDPQHPYTQLLVSSV 255

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

8-256

1.51e-53

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 175.94 E-value: 1.51e-53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLS 86
Cdd:COG1127    1 MSEPMIEVRNLTKSFGDRVV--LDGVSLDVPRGEILAIIGGSGSGKS-VLLkLIIGLLRPD----SGEILVDGQDITGLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PREYANLRgSELAMIFQEP-----MTSL-NPAFTLgdqlseavMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQ 160
Cdd:COG1127   74 EKELYELR-RRIGMLFQGGalfdsLTVFeNVAFPL--------REHTDLSEAEIRELVLEKLELVGLPGAADK---MPSE 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:COG1127  142 LSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKII 221

                        250
                 ....*....|....*.
gi 550714244 241 EQGSVEAIFADPqHPY 256
Cdd:COG1127  222 AEGTPEELLASD-DPW 236

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

13-257

2.55e-52

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 175.65 E-value: 2.55e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARI-VSGEmhfrrhDLRKLSP 87
Cdd:COG1135    2 IELENLSKTFptKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKS-TLIRCINLLerPTSGSVlVDGV------DLTALSE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANLRgSELAMIFQepmtslnpAFTLgdqLSeavmrhqtlSRaeamTVA------LQI--LEKVQIPA--AEM----- 152
Cdd:COG1135   75 RELRAAR-RKIGMIFQ--------HFNL---LS---------SR----TVAenvalpLEIagVPKAEIRKrvAELlelvg 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 153 ---RLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQ 229
Cdd:COG1135  130 lsdKADAYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICD 209

                        250       260
                 ....*....|....*....|....*...
gi 550714244 230 QVAVMYAGQVVEQGSVEAIFADPQHPYT 257
Cdd:COG1135  210 RVAVLENGRIVEQGPVLDVFANPQSELT 237

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

13-256

3.12e-52

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 172.30 E-value: 3.12e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSPREYA 91
Cdd:cd03261    1 IELRGLTKSFGGRTV--LKGVDLDVRRGEILAIIGPSGSGKS-TLLRLIvGLLRPD----SGEVLIDGEDISGLSEAELY 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRgSELAMIFQEP--MTSL----NPAFTLgdqlseavMRHQTLSRAEAMTVALQILEKVQIPAAEmrlKVYPHQLSGGM 165
Cdd:cd03261   74 RLR-RRMGMLFQSGalFDSLtvfeNVAFPL--------REHTRLSEEEIREIVLEKLEAVGLRGAE---DLYPAELSGGM 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:cd03261  142 KKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTP 221

                        250
                 ....*....|.
gi 550714244 246 EAIFADpQHPY 256
Cdd:cd03261  222 EELRAS-DDPL 231

CP_lyasePhnK

TIGR02323

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...

11-264

3.99e-51

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]

Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 170.01 E-value: 3.99e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   11 PVLRLQNLNvKFAGSPVSVlEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFR-----RHDLRKL 85
Cdd:TIGR02323   2 PLLQVSGLS-KSYGGGKGC-RDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPD----HGTATYImrsgaELELYQL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   86 SPREYANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVM----RHQTLSRAEAMtvalQILEKVQIPAAemRLKVYPHQL 161
Cdd:TIGR02323  76 SEAERRRLMRTEWGFVHQNPRDGLRMRVSAGANIGERLMaigaRHYGNIRATAQ----DWLEEVEIDPT--RIDDLPRAF 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:TIGR02323 150 SGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVE 229

                         250       260
                  ....*....|....*....|...
gi 550714244  242 QGSVEAIFADPQHPYTIGLMGSI 264
Cdd:TIGR02323 230 SGLTDQVLDDPQHPYTQLLVSSI 252

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

13-253

1.10e-50

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 168.28 E-value: 1.10e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYAn 92
Cdd:COG1122    1 IELENLSFSYPGGTP-ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPT----SGEVLVDGKDITKKNLRELR- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgSELAMIFQepmtslNPAftlgDQLSEAV--------MRHQTLSRAEAMTVALQILEKVQIpaAEMRLKVyPHQLSGG 164
Cdd:COG1122   75 ---RKVGLVFQ------NPD----DQLFAPTveedvafgPENLGLPREEIRERVEEALELVGL--EHLADRP-PHELSGG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:COG1122  139 QKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217


                 ....*....
gi 550714244 245 VEAIFADPQ 253
Cdd:COG1122  218 PREVFSDYE 226

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

29-245

9.58e-50

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 167.17 E-value: 9.58e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLlpasARIVSGEMHFRRHDLRKLSPREYANLRGsELAMIFQEPMTS 108
Cdd:PRK10419  27 VLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGL----ESPSQGNVSWRGEPLAKLNRAQRKAFRR-DIQMVFQDSISA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 LNPAFTLGDQLSEAvMRHQT-LSRAEAMTVALQILEKVQIPAAEM-RLkvyPHQLSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:PRK10419 102 VNPRKTVREIIREP-LRHLLsLDKAERLARASEMLRAVDLDDSVLdKR---PPQLSGGQLQRVCLARALAVEPKLLILDE 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 187 PTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:PRK10419 178 AVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPV 236

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

12-253

9.95e-50

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 165.83 E-value: 9.95e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVSV--LEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARI-VSGEmhfrrhDLRKLS 86
Cdd:cd03258    1 MIELKNVSKVFGDTGGKVtaLKDVSLSVPKGEIFGIIGRSGAGKS-TLIRCINGLerPTSGSVlVDGT------DLTLLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PREYANLRgSELAMIFQE--PMTSL----NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQ 160
Cdd:cd03258   74 GKELRKAR-RRIGMIFQHfnLLSSRtvfeNVALPL---------EIAGVPKAEIEERVLELLELVGL---EDKADAYPAQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:cd03258  141 LSGGQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVV 220

                        250
                 ....*....|...
gi 550714244 241 EQGSVEAIFADPQ 253
Cdd:cd03258  221 EEGTVEEVFANPQ 233

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

29-271

5.05e-49

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 164.98 E-value: 5.05e-49

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLlpasARIVSGEMHFRRHDLRKLSPREYANLRgSELAMIFQEPMTS 108
Cdd:TIGR02769  26 VLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGL----EKPAQGTVSFRGQDLYQLDRKQRRAFR-RDVQLVFQDSPSA 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  109 LNPAFTLGDQLSEAvMRHQT-LSRAEAMTVALQILEKVQIPAAEMRLkvYPHQLSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:TIGR02769 101 VNPRMTVRQIIGEP-LRHLTsLDESEQKARIAELLDMVGLRSEDADK--LPRQLSGGQLQRINIARALAVKPKLIVLDEA 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  188 TTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADpQHPYTIGLMGSI-PS 266
Cdd:TIGR02769 178 VSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLLSF-KHPAGRNLQSAVlPE 256


                  ....*
gi 550714244  267 LGVRK 271
Cdd:TIGR02769 257 HPVRR 261

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

12-255

2.28e-48

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 162.47 E-value: 2.28e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRkLSPREY 90
Cdd:COG1126    1 MIEIENLHKSFGDLEV--LKGISLDVEKGEVVVIIGPSGSGKS-TLLrCINLLEEPD----SGTITVDGEDLT-DSKKDI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRgSELAMIFQepmtSLN--PAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMRQR 168
Cdd:COG1126   73 NKLR-RKVGMVFQ----QFNlfPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLAD---KADAYPAQLSGGQQQR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:COG1126  145 VAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEF 223


                 ....*..
gi 550714244 249 FADPQHP 255
Cdd:COG1126  224 FENPQHE 230

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

12-249

2.42e-48

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 162.91 E-value: 2.42e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSPREY 90
Cdd:COG1120    1 MLEAENLSVGYGGRPV--LDDVSLSLPPGEVTALLGPNGSGKS-TLLrALAGLLKPS----SGEVLLDGRDLASLSRREL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLrgseLAMIFQEPmtSLNPAFTLGDqlseAVMR----HQTLSR---AEAMTVALQILEKVQIpaAEMRLKVYpHQLSG 163
Cdd:COG1120   74 ARR----IAYVPQEP--PAPFGLTVRE----LVALgrypHLGLFGrpsAEDREAVEEALERTGL--EHLADRPV-DELSG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:COG1120  141 GERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQG 220


                 ....*.
gi 550714244 244 SVEAIF 249
Cdd:COG1120  221 PPEEVL 226

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

13-248

1.10e-47

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 160.61 E-value: 1.10e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRklspREYAN 92
Cdd:COG1131    1 IEVRGLTKRYGD--KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPT----SGEVRVLGEDVA----RDPAE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEPmtSLNPAFTLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMRQRVMIA 172
Cdd:COG1131   71 VR-RRIGYVPQEP--ALYPDLTVRENL-RFFARLYGLPRKEARERIDELLELFGLTD---AADRKVGTLSGGMKQRLGLA 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:COG1131  144 LALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

9-234

1.29e-47

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 161.03 E-value: 1.29e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKL 85
Cdd:COG1116    4 AAPALELRGVSKRFptGGGGVTALDDVSLTVAAGEFVALVGPSGCGKS-TLLrLIAGLEKPT----SGEVLVDGKPVTGP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPReyanlrgseLAMIFQEPmtSLNPAFTLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGM 165
Cdd:COG1116   79 GPD---------RGVVFQEP--ALLPWLTVLDNV-ALGLELRGVPKAERRERARELLELVGLAGFEDA---YPHQLSGGM 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDV----TIQAQILALLntlkEETGTAVLMITHDlgvVAE---VAQQVAVM 234
Cdd:COG1116  144 RQRVAIARALANDPEVLLMDEPFGALDAltreRLQDELLRLW----QETGKTVLFVTHD---VDEavfLADRVVVL 212

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

14-257

7.17e-47

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 161.51 E-value: 7.17e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGS--PVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASAR-IVSGEmhfrrhDLRKLSPR 88
Cdd:PRK11153   3 ELKNISKVFPQGgrTIHALNNVSLHIPAGEIFGVIGASGAGKS-TLIRCINLLerPTSGRvLVDGQ------DLTALSEK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLRgSELAMIFQEpmtslnpaFTLgdqLSeavmrhqtlSRAEAMTVALQiLEKVQIPAAEMRLKV------------ 156
Cdd:PRK11153  76 ELRKAR-RQIGMIFQH--------FNL---LS---------SRTVFDNVALP-LELAGTPKAEIKARVtellelvglsdk 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 157 ---YPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAV 233
Cdd:PRK11153 134 adrYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAV 213

                        250       260
                 ....*....|....*....|....
gi 550714244 234 MYAGQVVEQGSVEAIFADPQHPYT 257
Cdd:PRK11153 214 IDAGRLVEQGTVSEVFSHPKHPLT 237

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

13-242

1.36e-45

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 154.55 E-value: 1.36e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSPRe 89
Cdd:cd03293    1 LEVRNVSKTYggGGGAVTALEDISLSVEEGEFVALVGPSGCGKS-TLLRIIaGLERPT----SGEVLVDGEPVTGPGPD- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanlrgseLAMIFQEP-----MTSL-NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSG 163
Cdd:cd03293   75 --------RGYVFQQDallpwLTVLdNVALGL---------ELQGVPKAEARERAEELLELVGLSGFENA---YPHQLSG 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYA--GQVVE 241
Cdd:cd03293  135 GMRQRVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVA 214


                 .
gi 550714244 242 Q 242
Cdd:cd03293  215 E 215

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

8-247

8.77e-45

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 152.97 E-value: 8.77e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLN--VKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRK 84
Cdd:COG4181    4 SSAPIIELRGLTktVGTGAGELTILKGISLEVEAGESVAIVGASGSGKS-TLLGLLaGLDRPT----SGTVRLAGQDLFA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  85 LSPREYANLRGSELAMIFQepmtslnpAFTLGDQLS--EAVMRHQTL-SRAEAMTVALQILEKVqipAAEMRLKVYPHQL 161
Cdd:COG4181   79 LDEDARARLRARHVGFVFQ--------SFQLLPTLTalENVMLPLELaGRRDARARARALLERV---GLGHRLDHYPAQL 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGvVAEVAQQVAVMYAGQVVE 241
Cdd:COG4181  148 SGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPA-LAARCDRVLRLRAGRLVE 226


                 ....*.
gi 550714244 242 QGSVEA 247
Cdd:COG4181  227 DTAATA 232

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

9-262

3.11e-44

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 154.87 E-value: 3.11e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSP 87
Cdd:COG3842    2 AMPALELENVSKRYGDVTA--LDDVSLSIEPGEFVALLGPSGCGKT-TLLrMIAGFETPD----SGRILLDGRDVTGLPP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REyanlRGseLAMIFQEP-----MTSL-NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQL 161
Cdd:COG3842   75 EK----RN--VGMVFQDYalfphLTVAeNVAFGL---------RMRGVPKAEIRARVAELLELVGLEGLADR---YPHQL 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:COG3842  137 SGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQ 216

                        250       260
                 ....*....|....*....|.
gi 550714244 242 QGSVEAIFADPQHPYTIGLMG 262
Cdd:COG3842  217 VGTPEEIYERPATRFVADFIG 237

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

14-238

3.19e-44

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 150.70 E-value: 3.19e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYANl 93
Cdd:cd03225    1 ELKNLSFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPT----SGEVLVDGKDLTKLSLKELRR- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  94 rgsELAMIFQepmtslNPAftlgDQLSEAV--------MRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGM 165
Cdd:cd03225   76 ---KVGLVFQ------NPD----DQFFGPTveeevafgLENLGLPEEEIEERVEEALELVGLEG---LRDRSPFTLSGGQ 139

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:cd03225  140 KQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

13-288

9.01e-44

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 153.76 E-value: 9.01e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLR-KLSPREy 90
Cdd:COG1118    3 IEVRNISKRFGS--FTLLDDVSLEIASGELVALLGPSGSGKT-TLLRIIaGLETPD----SGRIVLNGRDLFtNLPPRE- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anlRGseLAMIFQEP-----MTSL-NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGG 164
Cdd:COG1118   75 ---RR--VGFVFQHYalfphMTVAeNIAFGL---------RVRPPSKAEIRARVEELLELVQLEGLADR---YPSQLSGG 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:COG1118  138 QRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGT 217

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 550714244 245 VEAIFADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMP 288
Cdd:COG1118  218 PDEVYDRPATPFVARFLGCVNVLRGRVIGGQLEADGLTLPVAEP 261

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

12-241

2.56e-43

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 148.66 E-value: 2.56e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSiTslaLMGLLPASARIVSGEMHFRRHDLRKLSPREYA 91
Cdd:COG2884    1 MIRFENVSKRYPGGRE-ALSDVSLEIEKGEFVFLTGPSGAGKS-T---LLKLLYGEERPTSGQVLVNGQDLSRLKRREIP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRgSELAMIFQEpmtslnpaFTLGDQLS-----EAVMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMR 166
Cdd:COG2884   76 YLR-RRIGVVFQD--------FRLLPDRTvyenvALPLRVTGKSRKEIRRRVREVLDLVGLSD---KAKALPHELSGGEQ 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:COG2884  144 QRVAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEIN-RRGTTVLIATHDLELVDRMPKRVLELEDGRLVR 217

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

14-243

2.61e-43

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 147.58 E-value: 2.61e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03214    1 EVENLSVGYGGRTV--LDDLSLSIEAGEIVGILGPNGAGKS-TLLkTLAGLLKPS----SGEILLDGKDLASLSPKE--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgselamifqepmtslnpaftlgdqlseavmrhqtlsRAEAMTVALQILEKVQIpaAEMRLKVYpHQLSGGMRQRVMIA 172
Cdd:cd03214   71 --------------------------------------LARKIAYVPQALELLGL--AHLADRPF-NELSGGERQRVLLA 109

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03214  110 RALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180

LolD_lipo_ex

TIGR02211

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...

12-241

7.37e-43

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 147.50 E-value: 7.37e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   12 VLRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLPASArivSGEMHFRRHDLRKLSPRE 89
Cdd:TIGR02211   1 LLKCENLGKRYqeGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKS-TLLHLLGGLDNPT---SGEVLFNGQSLSKLSSNE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   90 YANLRGSELAMIFQepMTSLNPAFT-LGDQLSEAVMRHQtlSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQR 168
Cdd:TIGR02211  77 RAKLRNKKLGFIYQ--FHHLLPDFTaLENVAMPLLIGKK--SVKEAKERAYEMLEKVGL---EHRINHRPSELSGGERQR 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244  169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGvVAEVAQQVAVMYAGQVVE 241
Cdd:TIGR02211 150 VAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLE-LAKKLDRVLEMKDGQLFN 221

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

13-253

4.84e-42

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 146.31 E-value: 4.84e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNvKFAGSPvSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARIVSGEMHFrrhDL-RKLSPRE 89
Cdd:PRK11124   3 IQLNGIN-CFYGAH-QALFDITLDCPQGETLVLLGPSGAGKS-SLLRVLNLLemPRSGTLNIAGNHF---DFsKTPSDKA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRgSELAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRV 169
Cdd:PRK11124  77 IRELR-RNVGMVFQQ--YNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYADR---FPLHLSGGQQQRV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLkEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAiF 249
Cdd:PRK11124 151 AIARALMMEPQVLLFDEPTAALDPEITAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC-F 228


                 ....
gi 550714244 250 ADPQ 253
Cdd:PRK11124 229 TQPQ 232

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

13-253

5.05e-42

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 145.93 E-value: 5.05e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNvKFAGSpVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARIVSGEMHFrrhDL-RKLSPRE 89
Cdd:COG4161    3 IQLKNIN-CFYGS-HQALFDINLECPSGETLVLLGPSGAGKS-SLLRVLNLLetPDSGQLNIAGHQF---DFsQKPSEKA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRGsELAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIpaAEMRlKVYPHQLSGGMRQRV 169
Cdd:COG4161   77 IRLLRQ-KVGMVFQQ--YNLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARLRL--TDKA-DRFPLHLSGGQQQRV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEaIF 249
Cdd:COG4161  151 AIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELS-QTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDAS-HF 228


                 ....
gi 550714244 250 ADPQ 253
Cdd:COG4161  229 TQPQ 232

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

13-248

1.58e-41

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 144.25 E-value: 1.58e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKS--ITSLALMGLLPASARiVSGEMHFRRHDLRKLSPREY 90
Cdd:cd03260    1 IELRDLNVYYGD--KHALKDISLDIPKGEITALIGPSGCGKStlLRLLNRLNDLIPGAP-DEGEVLLDGKDIYDLDVDVL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 AnLRgSELAMIFQEPmtslNP-AFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAaEMRLKVYPHQLSGGMRQRV 169
Cdd:cd03260   78 E-LR-RRVGMVFQKP----NPfPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWD-EVKDRLHALGLSGGQQQRL 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:cd03260  151 CLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

13-243

2.18e-41

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 143.43 E-value: 2.18e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03259    1 LELKGLSKTYGSVRA--LDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPD----SGEILIDGRDVTGVPPER--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGseLAMIFQEPmtSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIA 172
Cdd:cd03259   72 -RN--IGMVFQDY--ALFPHLTVAENIAFG-LKLRGVPKAEIRARVRELLELVGLEGLLNR---YPHELSGGQQQRVALA 142

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03259  143 RALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

8-249

8.50e-41

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 142.92 E-value: 8.50e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSitSL--ALMGLLPASarivSGEMHFRRHDLRKL 85
Cdd:COG1121    2 MMMPAIELENLTVSYGGRPV--LEDVSLTIPPGEFVAIVGPNGAGKS--TLlkAILGLLPPT----SGTVRLFGKPPRRA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPReyanlrgseLAMIFQepMTSLNPAFtlgdQLS--EAVM----RHQTLSR---AEAMTVALQILEKVQIPA-AEMRLk 155
Cdd:COG1121   74 RRR---------IGYVPQ--RAEVDWDF----PITvrDVVLmgryGRRGLFRrpsRADREAVDEALERVGLEDlADRPI- 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 vypHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMy 235
Cdd:COG1121  138 ---GELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLL- 212

                        250
                 ....*....|....
gi 550714244 236 AGQVVEQGSVEAIF 249
Cdd:COG1121  213 NRGLVAHGPPEEVL 226

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

13-239

2.22e-40

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 140.72 E-value: 2.22e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSPREYa 91
Cdd:COG4619    1 LELEGLSFRVGGKPI--LSPVSLTLEAGECVAITGPSGSGKS-TLLrALADLDPPT----SGEIYLDGKPLSAMPPPEW- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 nlRgSELAMIFQEPmtslnPAF--TLGDQLSEAV-MRHQTLSRAEAmtvaLQILEKVQIPAAEMRLKVypHQLSGGMRQR 168
Cdd:COG4619   73 --R-RQVAYVPQEP-----ALWggTVRDNLPFPFqLRERKFDRERA----LELLERLGLPPDILDKPV--ERLSGGERQR 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:COG4619  139 LALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209

PhnC

COG3638

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...

11-248

7.10e-40

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 140.58 E-value: 7.10e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSPRE 89
Cdd:COG3638    1 PMLELRNLSKRYPGGTP-ALDDVSLEIERGEFVALIGPSGAGKS-TLLrCLNGLVEPT----SGEILVDGQDVTALRGRA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRgSELAMIFQEpmtslnpaFTLGDQLS--EAVM-----RHQTLS------RAEAMTVALQILEKVQIPA-AEMRlk 155
Cdd:COG3638   75 LRRLR-RRIGMIFQQ--------FNLVPRLSvlTNVLagrlgRTSTWRsllglfPPEDRERALEALERVGLADkAYQR-- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 vyPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:COG3638  144 --ADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLR 221

                        250
                 ....*....|...
gi 550714244 236 AGQVVEQGSVEAI 248
Cdd:COG3638  222 DGRVVFDGPPAEL 234

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

13-239

1.99e-38

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 135.74 E-value: 1.99e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLpasARIVSGEMHFRRHDLRKlSPREYAN 92
Cdd:cd03262    1 IEIKNLHKSFGDFHV--LKGIDLTVKKGEVVVIIGPSGSGKS-TLLRCINLL---EEPDSGTIIIDGLKLTD-DKKNINE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAaemRLKVYPHQLSGGMRQRVMIA 172
Cdd:cd03262   74 LR-QKVGMVFQQ--FNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLAD---KADAYPAQLSGGQQQRVAIA 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:cd03262  148 RALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

13-238

3.38e-38

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 134.24 E-value: 3.38e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03229    1 LELKNVSKRYGQ--KTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLE----EPDSGSILIDGEDLTDLEDELPPL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgsELAMIFQEPmtslnpaftlgdqlseAVMRHqtlsraeaMTValqiLEKVQIPaaemrlkvyphqLSGGMRQRVMIA 172
Cdd:cd03229   75 RR--RIGMVFQDF----------------ALFPH--------LTV----LENIALG------------LSGGQQQRVALA 112

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:cd03229  113 RALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178

heterocyst_DevA

TIGR02982

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...

29-220

4.56e-38

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.

Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 135.15 E-value: 4.56e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLpasaRIV-SGEMHFRRHDLRKLSPREYANLRGSeLAMIFQEpmT 107
Cdd:TIGR02982  20 VLFDINLEINPGEIVILTGPSGSGKT-TLLTLIGGL----RSVqEGSLKVLGQELHGASKKQLVQLRRR-IGYIFQA--H 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  108 SLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:TIGR02982  92 NLLGFLTARQNVQMALELQPNLSYQEARERARAMLEAVGL---GDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEP 168

                         170       180       190
                  ....*....|....*....|....*....|...
gi 550714244  188 TTALDVTIQAQILALLNTLKEETGTAVLMITHD 220
Cdd:TIGR02982 169 TAALDSKSGRDVVELMQKLAKEQGCTILMVTHD 201

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

13-239

4.88e-38

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 133.29 E-value: 4.88e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKlsprEYAN 92
Cdd:cd03230    1 IEVRNLSKRYGKKTA--LDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPD----SGEIKVLGKDIKK----EPEE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRGsELAMIFQEPmtSLNPAFTLGDQLseavmrhqtlsraeamtvalqilekvqipaaemrlkvyphQLSGGMRQRVMIA 172
Cdd:cd03230   71 VKR-RIGYLPEEP--SLYENLTVRENL----------------------------------------KLSGGMKQRLALA 107

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:cd03230  108 QALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173

PRK15112

peptide ABC transporter ATP-binding protein SapF;

27-263

5.57e-38

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 136.46 E-value: 5.57e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHdlrKLSPREYAnLRGSELAMIFQEPM 106
Cdd:PRK15112  26 VEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPT----SGELLIDDH---PLHFGDYS-YRSQRIRMIFQDPS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 107 TSLNPAFTLGdQLSEAVMRHQT-LSRAEAMTVALQILEKVQIPAAEMrlKVYPHQLSGGMRQRVMIAMALINHPKLLIAD 185
Cdd:PRK15112  98 TSLNPRQRIS-QILDFPLRLNTdLEPEQREKQIIETLRQVGLLPDHA--SYYPHMLAPGQKQRLGLARALILRPKVIIAD 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 186 EPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGLMGS 263
Cdd:PRK15112 175 EALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPLHELTKRLIAG 252

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

13-248

1.15e-36

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 131.92 E-value: 1.15e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFaGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03256    1 IEVENLSKTY-PNGKKALKDVSLSINPGEFVALIGPSGAGKS----TLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEpmtslnpaFTLGDQLS--EAVM-----RHQTL-------SRAEaMTVALQILEKVQI-PAAEMRLKvy 157
Cdd:cd03256   76 LR-RQIGMIFQQ--------FNLIERLSvlENVLsgrlgRRSTWrslfglfPKEE-KQRALAALERVGLlDKAYQRAD-- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 phQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:cd03256  144 --QLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDG 221

                        250
                 ....*....|.
gi 550714244 238 QVVEQGSVEAI 248
Cdd:cd03256  222 RIVFDGPPAEL 232

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

13-253

1.31e-36

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 131.79 E-value: 1.31e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03219    1 LEVRGLTKRFGG--LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPT----SGSVLFDGEDITGLPPHEIAR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGseLAMIFQepMTSLNPAFTLGDQLSEAVMRHQTLS---------RAEAMTVALQILEKVQIPAaemRLKVYPHQLSG 163
Cdd:cd03219   75 -LG--IGRTFQ--IPRLFPELTVLENVMVAAQARTGSGlllararreEREARERAEELLERVGLAD---LADRPAGELSY 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03219  147 GQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRVTVLDQGRVIAEG 225

                        250
                 ....*....|
gi 550714244 244 SVEAIFADPQ 253
Cdd:cd03219  226 TPDEVRNNPR 235

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

9-248

1.73e-36

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 137.07 E-value: 1.73e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSiTslaLM----GLLPASarivSGEMHFRRHDLRK 84
Cdd:COG1129    1 AEPLLEMRGISKSFGG--VKALDGVSLELRPGEVHALLGENGAGKS-T---LMkilsGVYQPD----SGEILLDGEPVRF 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  85 LSPREyANLRGseLAMIFQEPmtSLNPAFT------LGDQLseavMRHQTLSRAEAMTVALQILEKVQI---PAAEMRlk 155
Cdd:COG1129   71 RSPRD-AQAAG--IAIIHQEL--NLVPNLSvaenifLGREP----RRGGLIDWRAMRRRARELLARLGLdidPDTPVG-- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 vyphQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:COG1129  140 ----DLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLR 214

                        250
                 ....*....|...
gi 550714244 236 AGQVVEQGSVEAI 248
Cdd:COG1129  215 DGRLVGTGPVAEL 227

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

30-189

1.74e-36

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 128.53 E-value: 1.74e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPReyanLRGSELAMIFQEPmtSL 109
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPT----EGTILLDGQDLTDDERK----SLRKEIGYVFQDP--QL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  110 NPAFTLGDQLSEAVmRHQTLSRAEAMTVALQILEKVQIP-AAEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPT 188
Cdd:pfam00005  71 FPRLTVRENLRLGL-LLKGLSKREKDARAEEALEKLGLGdLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149


                  .
gi 550714244  189 T 189
Cdd:pfam00005 150 A 150

ECF_ATPase_1

TIGR04520

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...

13-260

2.41e-36

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 131.78 E-value: 2.41e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARI-VSGemhfrrhdLRKLSPREY 90
Cdd:TIGR04520   1 IEVENVSFSYPESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLlPTSGKVtVDG--------LDTLDEENL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   91 ANLRgSELAMIFQepmtslNPaftlGDQLseaVmrhqtlsraeAMTVALQI---LEKVQIPAAEMRLKVY---------- 157
Cdd:TIGR04520  73 WEIR-KKVGMVFQ------NP----DNQF---V----------GATVEDDVafgLENLGVPREEMRKRVDealklvgmed 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  158 -----PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEvAQQVA 232
Cdd:TIGR04520 129 frdrePHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVI 207

                         250       260
                  ....*....|....*....|....*...
gi 550714244  233 VMYAGQVVEQGSVEAIFADPQHPYTIGL 260
Cdd:TIGR04520 208 VMNKGKIVAEGTPREIFSQVELLKEIGL 235

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

13-285

3.58e-36

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 133.66 E-value: 3.58e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSPREya 91
Cdd:COG3839    4 LELENVSKSYGG--VEALKDIDLDIEDGEFLVLLGPSGCGKS-TLLRMIaGLEDPT----SGEILIGGRDVTDLPPKD-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 nlRGseLAMIFQEP-----MTSL-NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGM 165
Cdd:COG3839   75 --RN--IAMVFQSYalyphMTVYeNIAFPL---------KLRKVPKAEIDRRVREAAELLGL---EDLLDRKPKQLSGGQ 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLgvvAEV---AQQVAVMYAGQVVEQ 242
Cdd:COG3839  139 RQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQ---VEAmtlADRIAVMNDGRIQQV 215

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 550714244 243 GSVEAIFADPQHPYTIGLMGSIP----SLGVRKGQLSTIPGSVPLPE 285
Cdd:COG3839  216 GTPEELYDRPANLFVAGFIGSPPmnllPGTVEGGGVRLGGVRLPLPA 262

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

14-238

5.35e-36

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 127.75 E-value: 5.35e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYANl 93
Cdd:cd00267    1 EIENLSFRYGGRTA--LDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPT----SGEILIDGKDIAKLPLEELRR- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  94 rgsELAMIFQepmtslnpaftlgdqlseavmrhqtlsraeamtvalqilekvqipaaemrlkvyphqLSGGMRQRVMIAM 173
Cdd:cd00267   74 ---RIGYVPQ---------------------------------------------------------LSGGQRQRVALAR 93

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 174 ALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:cd00267   94 ALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

13-255

1.03e-35

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 129.10 E-value: 1.03e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSvledISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSPREya 91
Cdd:COG3840    2 LRLDDLTYRYGDFPLR----FDLTIAAGERVAILGPSGAGKS-TLLNLIaGFLPPD----SGRILWNGQDLTALPPAE-- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 nlRGseLAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVAlQILEKVQIPAAEMRLkvyPHQLSGGMRQRVMI 171
Cdd:COG3840   71 --RP--VSMLFQE--NNLFPHLTVAQNIGLGLRPGLKLTAEQRAQVE-QALERVGLAGLLDRL---PGQLSGGQRQRVAL 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 172 AMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:COG3840  141 ARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDG 220


                 ....
gi 550714244 252 PQHP 255
Cdd:COG3840  221 EPPP 224

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

13-263

1.20e-35

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 129.34 E-value: 1.20e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVlEDISLAVRAGETLALVGESGCGKSiTSLALMGLLPASArivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03295    1 IEFENVTKRYGGGKKAV-NNLNLEIAKGEFLVLIGPSGSGKT-TTMKMINRLIEPT---SGEIFIDGEDIREQDPVE--- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRGSeLAMIFQEpmTSLNPAFTLGDQLSeAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKvYPHQLSGGMRQRVMIA 172
Cdd:cd03295   73 LRRK-IGYVIQQ--IGLFPHMTVEENIA-LVPKLLKWPKEKIRERADELLALVGLDPAEFADR-YPHELSGGQQQRVGVA 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:cd03295  148 RALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSP 227

                        250
                 ....*....|.
gi 550714244 253 QHPYTIGLMGS 263
Cdd:cd03295  228 ANDFVAEFVGA 238

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

9-242

3.08e-35

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 128.01 E-value: 3.08e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGSPVS--VLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLPASArivSGEMHFRRHDLRKLS 86
Cdd:PRK11629   2 NKILLQCDNLCKRYQEGSVQtdVLHNVSFSIGEGEMMAIVGSSGSGKS-TLLHLLGGLDTPT---SGDVIFNGQPMSKLS 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PREYANLRGSELAMIFQepMTSLNPAFTLGDQLSEAVMRHQTlSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMR 166
Cdd:PRK11629  78 SAAKAELRNQKLGFIYQ--FHHLLPDFTALENVAMPLLIGKK-KPAEINSRALEMLAAVGL---EHRANHRPSELSGGER 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAvMYAGQVVEQ 242
Cdd:PRK11629 152 QRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLE-MRDGRLTAE 226

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

20-256

6.27e-35

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 128.14 E-value: 6.27e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  20 VKFAGSPVSVlEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSPREYANLRGSEL 98
Cdd:cd03294   31 LKKTGQTVGV-NDVSLDVREGEIFVIMGLSGSGKS-TLLRCInRLIEPT----SGKVLIDGQDIAAMSRKELRELRRKKI 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  99 AMIFQE----P-MTSL-NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIA 172
Cdd:cd03294  105 SMVFQSfallPhRTVLeNVAFGL---------EVQGVPRAEREERAAEALELVGL---EGWEHKYPDELSGGMQQRVGLA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:cd03294  173 RALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNP 252


                 ....
gi 550714244 253 QHPY 256
Cdd:cd03294  253 ANDY 256

oligo_HPY

TIGR01727

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...

238-323

9.93e-35

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 213647 [Multi-domain] Cd Length: 87 Bit Score: 122.09 E-value: 9.93e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  238 QVVEQGSVEAIFADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRCHAEKPPLTMLGTG 317
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIKKRDRKLISIPGEVPSLINLPSGCRFYPRCPYAQDECRKEPPALVEIAEG 80


                  ....*.
gi 550714244  318 HQVACF 323
Cdd:TIGR01727  81 HRVACH 86

L_ocin_972_ABC

TIGR03608

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...

15-231

1.10e-34

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]

Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 125.81 E-value: 1.10e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   15 LQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLLpasARIVSGEMHFRRHDLRKLSPREYANLR 94
Cdd:TIGR03608   1 LKNISKKFGDK--VILDDLNLTIEKGKMYAIIGESGSGKS-TLLNIIGLL---EKFDSGQVYLNGQETPPLNSKKASKFR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   95 GSELAMIFQEpmtslnpaFTLGDQLS-----EAVMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRV 169
Cdd:TIGR03608  75 REKLGYLFQN--------FALIENETveenlDLGLKYKKLSKKEKREKKKEALEKVGL---NLKLKQKIYELSGGEQQRV 143

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244  170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLgVVAEVAQQV 231
Cdd:TIGR03608 144 ALARAILKPPPLILADEPTGSLDPKNRDEVLDLLLELNDE-GKTIIIVTHDP-EVAKQADRV 203

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

13-253

1.29e-34

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 126.68 E-value: 1.29e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSpvsVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03299    1 LKVENLSKDWKEF---KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPD----SGKILLNGKDITNLPPEK--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGseLAMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIA 172
Cdd:cd03299   71 -RD--ISYVPQN--YALFPHMTVYKNIAYG-LKKRKVDKKEIERKVLEIAEMLGI---DHLLNRKPETLSGGEQQRVAIA 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:cd03299  142 RALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKP 221


                 .
gi 550714244 253 Q 253
Cdd:cd03299  222 K 222

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

15-257

1.84e-34

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 126.40 E-value: 1.84e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARIVSGEMHFRRHdlRKLSPREYA- 91
Cdd:PRK11264   6 VKNLVKKFHGQ--TVLHGIDLEVKPGEVVAIIGPSGSGKT-TLLRCINLLeqPEAGTIRVGDITIDTA--RSLSQQKGLi 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 -NLRgSELAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEmrlKVYPHQLSGGMRQRVM 170
Cdd:PRK11264  81 rQLR-QHVGFVFQN--FNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKE---TSYPRRLSGGQQQRVA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLmITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:PRK11264 155 IARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVI-VTHEMSFARDVADRAIFMDQGRIVEQGPAKALFA 233


                 ....*..
gi 550714244 251 DPQHPYT 257
Cdd:PRK11264 234 DPQQPRT 240

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

13-250

1.88e-34

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 133.42 E-value: 1.88e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitSLA--LMGLLPASarivSGEMHFRRHDLRKLSPREy 90
Cdd:COG2274  474 IELENVSFRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKS--TLLklLLGLYEPT----SGRILIDGIDLRQIDPAS- 546

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anLRGSeLAMIFQEPMTslnpaF--TLGDQLSeavMRHQTLSRAEAMTVA--LQILEKVQipAAEMRL--KVYPH--QLS 162
Cdd:COG2274  547 --LRRQ-IGVVLQDVFL-----FsgTIRENIT---LGDPDATDEEIIEAArlAGLHDFIE--ALPMGYdtVVGEGgsNLS 613

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 GGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQ 242
Cdd:COG2274  614 GGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHRLSTIRL-ADRIIVLDKGRIVED 690


                 ....*...
gi 550714244 243 GSVEAIFA 250
Cdd:COG2274  691 GTHEELLA 698

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

13-251

2.12e-34

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 125.62 E-value: 2.12e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03224    1 LEVENLNAGYGKSQI--LFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPR----SGSIRFDGRDITGLPPHERAR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGseLAMIFQEPMtsLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILekvqiPAAEMRLKVYPHQLSGGMRQRVMIA 172
Cdd:cd03224   75 -AG--IGYVPEGRR--IFPELTVEENLLLGAYARRRAKRKARLERVYELF-----PRLKERRKQLAGTLSGGEQQMLAIA 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:cd03224  145 RALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLAD 222

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

12-248

5.09e-34

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 124.97 E-value: 5.09e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSPRey 90
Cdd:COG4555    1 MIEVENLSKKYGKVPA--LKDVSFTAKDGEITGLLGPNGAGKT-TLLrMLAGLLKPD----SGSILIDGEDVRKEPRE-- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anLRgSELAMIFQEPMtsLNPAFTLGDQLSEAVMRHQtLSRAEAMTVALQILEKVQIPA-AEMRLkvypHQLSGGMRQRV 169
Cdd:COG4555   72 --AR-RQIGVLPDERG--LYDRLTVRENIRYFAELYG-LFDEELKKRIEELIELLGLEEfLDRRV----GELSTGMKKKV 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:COG4555  142 ALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219

COG4559

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

13-252

1.67e-33

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 124.07 E-value: 1.67e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHFRRHDLRKLSPREYA 91
Cdd:COG4559    2 LEAENLSVRLGGRTL--LDDVSLTLRPGELTAIIGPNGAGKS-TLLkLLTGELTPS----SGEVRLNGRPLAAWSPWELA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRgselAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTlSRAEAMTVALQILEKVQIPAAEMRLkvYPhQLSGGMRQRVMI 171
Cdd:COG4559   75 RRR----AVLPQH--SSLAFPFTVEEVVALGRAPHGS-SAAQDRQIVREALALVGLAHLAGRS--YQ-TLSGGEQQRVQL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 172 AMALI-------NHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:COG4559  145 ARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGT 223


                 ....*...
gi 550714244 245 VEAIFADP 252
Cdd:COG4559  224 PEEVLTDE 231

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

13-238

1.83e-33

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 121.34 E-value: 1.83e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKS-ITSLaLMGLLPASarivSGEMHFRRHDLRKLSPREYA 91
Cdd:cd03228    1 IEFKNVSFSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKStLLKL-LLRLYDPT----SGEILIDGVDLRDLDLESLR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLrgseLAMIFQEPmtslnpaftlgdqlseaVMRHQTlsraeamtvalqILEKVqipaaemrlkvyphqLSGGMRQRVMI 171
Cdd:cd03228   76 KN----IAYVPQDP-----------------FLFSGT------------IRENI---------------LSGGQRQRIAI 107

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 172 AMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVaEVAQQVAVMYAGQ 238
Cdd:cd03228  108 ARALLRDPPILILDEATSALDPETEALILEALRALAK--GKTVIVIAHRLSTI-RDADRIIVLDDGR 171

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

14-234

1.93e-33

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 122.64 E-value: 1.93e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPA---SARIVSGEMHFRRHDLRKLSPRE 89
Cdd:cd03235    1 EVEDLTVSYGGHPV--LEDVSFEVKPGEFLAIVGPNGAGKS-TLLkAILGLLKPtsgSIRVFGKPLEKERKRIGYVPQRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YAN----LRGSELAMifqepmTSLNPAFTLGDQLSEAVMRhqtlsraeamtVALQILEKVQIPA-AEMRLKvyphQLSGG 164
Cdd:cd03235   78 SIDrdfpISVRDVVL------MGLYGHKGLFRRLSKADKA-----------KVDEALERVGLSElADRQIG----ELSGG 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVM 234
Cdd:cd03235  137 QQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

20-246

2.28e-33

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 122.86 E-value: 2.28e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  20 VKFAGSPVSVlEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRklspREYANLRGSeLA 99
Cdd:cd03265    7 VKKYGDFEAV-RGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPT----SGRATVAGHDVV----REPREVRRR-IG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 100 MIFQEPmtSLNPAFTLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRLKVYphqlSGGMRQRVMIAMALINH 178
Cdd:cd03265   77 IVFQDL--SVDDELTGWENL-YIHARLYGVPGAERRERIDELLDFVGLlEAADRLVKTY----SGGMRRRLEIARSLVHR 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 179 PKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVE 246
Cdd:cd03265  150 PEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPE 217

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

13-240

2.64e-33

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 120.61 E-value: 2.64e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyAN 92
Cdd:cd03216    1 LELRGITKRFGG--VKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPD----SGEILVDGKEVSFASPRD-AR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRGseLAMIfqepmtslnpaftlgdqlseavmrhqtlsraeamtvalqilekvqipaaemrlkvypHQLSGGMRQRVMIA 172
Cdd:cd03216   74 RAG--IAMV---------------------------------------------------------YQLSVGERQMVEIA 94

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:cd03216   95 RALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

10-234

4.29e-33

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 122.16 E-value: 4.29e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFA-----GSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRH---- 80
Cdd:COG4778    2 TTLLEVENLSKTFTlhlqgGKRLPVLDGVSFSVAAGECVALTGPSGAGKS----TLLKCIYGNYLPDSGSILVRHDggwv 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  81 DLRKLSPREYANLRGSELAMIFQ----EPMTSlnpafTLgdqlsEAVM---RHQTLSRAEAMTVALQILEKVQIPAaemR 153
Cdd:COG4778   78 DLAQASPREILALRRRTIGYVSQflrvIPRVS-----AL-----DVVAeplLERGVDREEARARARELLARLNLPE---R 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 154 L-KVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVA 232
Cdd:COG4778  145 LwDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVV 223


                 ..
gi 550714244 233 VM 234
Cdd:COG4778  224 DV 225

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-257

5.19e-33

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 122.84 E-value: 5.19e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   1 MTTIPFkDSTPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKS--ITSLALMGLLPASARiVSGEMHFR 78
Cdd:COG1117    1 MTAPAS-TLEPKIEVRNLNVYYGDKQA--LKDINLDIPENKVTALIGPSGCGKStlLRCLNRMNDLIPGAR-VEGEILLD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  79 RHDL--RKLSPREyanLRgSELAMIFQEPmtslNP-AFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKvqipAA---EM 152
Cdd:COG1117   77 GEDIydPDVDVVE---LR-RRVGMVFQKP----NPfPKSIYDNVAYGLRLHGIKSKSELDEIVEESLRK----AAlwdEV 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 153 --RLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQ 230
Cdd:COG1117  145 kdRLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD--YTIVIVTHNMQQAARVSDY 222

                        250       260
                 ....*....|....*....|....*..
gi 550714244 231 VAVMYAGQVVEQGSVEAIFADPQHPYT 257
Cdd:COG1117  223 TAFFYLGELVEFGPTEQIFTNPKDKRT 249

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

13-263

5.34e-33

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 122.45 E-value: 5.34e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03296    3 IEVRNVSKRFGDFVA--LDDVSLDIPSGELVALLGPSGSGKT----TLLRLIAGLERPDSGTILFGGEDATDVPVQE--- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgSELAMIFQ-----EPMTSL-NPAFTLgdqlsEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMR 166
Cdd:cd03296   74 ---RNVGFVFQhyalfRHMTVFdNVAFGL-----RVKPRSERPPEAEIRAKVHELLKLVQLDWLADR---YPAQLSGGQR 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVE 246
Cdd:cd03296  143 QRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPD 222

                        250
                 ....*....|....*..
gi 550714244 247 AIFADPQHPYTIGLMGS 263
Cdd:cd03296  223 EVYDHPASPFVYSFLGE 239

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

13-253

1.28e-32

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 121.19 E-value: 1.28e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPreyaN 92
Cdd:cd03300    1 IELENVSKFYGGFVA--LDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPT----SGEILLDGKDITNLPP----H 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRGseLAMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIA 172
Cdd:cd03300   71 KRP--VNTVFQN--YALFPHLTVFENIAFG-LRLKKLPKAEIKERVAEALDLVQLEGYANR---KPSQLSGGQQQRVAIA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:cd03300  143 RALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEP 222


                 .
gi 550714244 253 Q 253
Cdd:cd03300  223 A 223

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

13-245

1.76e-32

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 120.30 E-value: 1.76e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRklSPREYAn 92
Cdd:cd03263    1 LQIRNLTKTYKKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPT----SGTAYINGYSIR--TDRKAA- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrGSELAMIFQEPMtsLNPAFTlgdqlseaVMRH-------QTLSRAEAMTVALQILEKVQIPAAEMRLkvyPHQLSGGM 165
Cdd:cd03263   74 --RQSLGYCPQFDA--LFDELT--------VREHlrfyarlKGLPKSEIKEEVELLLRVLGLTDKANKR---ARTLSGGM 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:cd03263  139 KRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216

ABC_phnC

TIGR02315

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...

12-251

2.29e-32

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]

Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 120.87 E-value: 2.29e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   12 VLRLQNLNVKFaGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLRKLSPREYA 91
Cdd:TIGR02315   1 MLEVENLSKVY-PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLV----EPSSGSILLEGTDITKLRGKKLR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   92 NLRgSELAMIFQEpMTSLNPAFTLGDQLSEAVMRHQTL-------SRAEAMtVALQILEKVQIPA-AEMRLKvyphQLSG 163
Cdd:TIGR02315  76 KLR-RRIGMIFQH-YNLIERLTVLENVLHGRLGYKPTWrsllgrfSEEDKE-RALSALERVGLADkAYQRAD----QLSG 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:TIGR02315 149 GQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDG 228


                  ....*...
gi 550714244  244 SVEAIFAD 251
Cdd:TIGR02315 229 APSELDDE 236

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

9-246

4.02e-32

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 125.14 E-value: 4.02e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKS----ItslaLMGLLPASarivSGEMHFRRHDLRK 84
Cdd:COG3845    2 MPPALELRGITKRFGG--VVANDDVSLTVRPGEIHALLGENGAGKStlmkI----LYGLYQPD----SGEILIDGKPVRI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  85 LSPREyANLRGseLAMIFQEPMtsLNPAFT------LGdqLSEAVMRHQTLSRAEAMTVALqilekvqipAAEMRLKVYP 158
Cdd:COG3845   72 RSPRD-AIALG--IGMVHQHFM--LVPNLTvaenivLG--LEPTKGGRLDRKAARARIREL---------SERYGLDVDP 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 ----HQLSGGMRQRVMIAMALINHPKLLIADEPTTALdvTIQ--AQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVA 232
Cdd:COG3845  136 dakvEDLSVGEQQRVEILKALYRGARILILDEPTAVL--TPQeaDELFEILRRLAAE-GKSIIFITHKLREVMAIADRVT 212

                        250
                 ....*....|....
gi 550714244 233 VMYAGQVVEQGSVE 246
Cdd:COG3845  213 VLRRGKVVGTVDTA 226

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

11-251

5.06e-32

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 120.26 E-value: 5.06e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREY 90
Cdd:PRK13548   1 AMLEARNLSVRLGGRTL--LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPD----SGEVRLNGRPLADWSPAEL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRgselAMIFQEpmTSLNPAFTLgdqlsEAVMR----HQTLSRAEAMTVALQILEKVQIPAAEMRLkvYPhQLSGGMR 166
Cdd:PRK13548  75 ARRR----AVLPQH--SSLSFPFTV-----EEVVAmgraPHGLSRAEDDALVAAALAQVDLAHLAGRD--YP-QLSGGEQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMALI------NHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:PRK13548 141 QRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLV 220

                        250
                 ....*....|.
gi 550714244 241 EQGSVEAIFAD 251
Cdd:PRK13548 221 ADGTPAEVLTP 231

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

8-247

8.71e-32

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 124.87 E-value: 8.71e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSP 87
Cdd:COG4988  332 AGPPSIELEDVSFSYPGGRP-ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPY----SGSILINGVDLSDLDP 406

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANLrgseLAMIFQEPMTslnPAFTLGDQLseavmrhqTLSRAEAMTVAL-QILEKVQIPAAEMRLkvyPH------- 159
Cdd:COG4988  407 ASWRRQ----IAWVPQNPYL---FAGTIRENL--------RLGRPDASDEELeAALEAAGLDEFVAAL---PDgldtplg 468

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 ----QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMY 235
Cdd:COG4988  469 eggrGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALLAQ-ADRILVLD 545

                        250
                 ....*....|..
gi 550714244 236 AGQVVEQGSVEA 247
Cdd:COG4988  546 DGRIVEQGTHEE 557

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

11-260

1.17e-31

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 119.73 E-value: 1.17e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMhfrrhdlrKLSPRE 89
Cdd:PRK13635   4 EIIRVEHISFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLlPEAGTITVGGM--------VLSEET 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRgSELAMIFQEPMTSLNPAfTLGDQLSEAvMRHQTLSRAEamtvalqILEKVQIPAAEMRLKVY----PHQLSGGM 165
Cdd:PRK13635  76 VWDVR-RQVGMVFQNPDNQFVGA-TVQDDVAFG-LENIGVPREE-------MVERVDQALRQVGMEDFlnrePHRLSGGQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSV 245
Cdd:PRK13635 146 KQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTP 224

                        250
                 ....*....|....*
gi 550714244 246 EAIFADPQHPYTIGL 260
Cdd:PRK13635 225 EEIFKSGHMLQEIGL 239

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

11-220

1.52e-31

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 117.58 E-value: 1.52e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKsiTSL--ALMGLLPASArivsGEMHFRRHDLRKlSPR 88
Cdd:COG4133    1 MMLEAENLSCRRGERLL--FSGLSFTLAAGEALALTGPNGSGK--TTLlrILAGLLPPSA----GEVLWNGEPIRD-ARE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYAnlrgSELAMIFQEPMtsLNPAFTLGDQLSEAVMRHQTLSRAEAmtvALQILEKVQIPAaemRLKVYPHQLSGGMRQR 168
Cdd:COG4133   72 DYR----RRLAYLGHADG--LKPELTVRENLRFWAALYGLRADREA---IDEALEAVGLAG---LADLPVRQLSAGQKRR 139

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHD 220
Cdd:COG4133  140 VALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLAR-GGAVLLTTHQ 190

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

26-255

2.24e-31

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 118.27 E-value: 2.24e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  26 PVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMhfRRHDLRKLSPREYANLRGSELAMIFQEp 105
Cdd:PRK09493  13 PTQVLHNIDLNIDQGEVVVIIGPSGSGKS----TLLRCINKLEEITSGDL--IVDGLKVNDPKVDERLIRQEAGMVFQQ- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 106 mtslnpaFTLGDQLS--EAVM----RHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHP 179
Cdd:PRK09493  86 -------FYLFPHLTalENVMfgplRVRGASKEEAEKQARELLAKVGL---AERAHHYPSELSGGQQQRVAIARALAVKP 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 180 KLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLmITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHP 255
Cdd:PRK09493 156 KLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVI-VTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQ 230

PhnT2

TIGR03265

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...

9-292

4.10e-31

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 120.14 E-value: 4.10e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    9 STPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGL-LPASARIVSGEmhfrrHDLRKLSP 87
Cdd:TIGR03265   1 SSPYLSIDNIRKRFGA--FTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLeRQTAGTIYQGG-----RDITRLPP 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   88 --REYAnlrgselaMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEmrlKVYPHQLSGGM 165
Cdd:TIGR03265  74 qkRDYG--------IVFQS--YALFPNLTVADNIAYG-LKNRGMGRAEVAERVAELLDLVGLPGSE---RKYPGQLSGGQ 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:TIGR03265 140 QQRVALARALATSPGLLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTP 219

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244  246 EAIFADPQHPYT---IGLMGSIP-------SLGVRKGQLSTIPGSVPLPESMPQGCR 292
Cdd:TIGR03265 220 QEIYRHPATPFVadfVGEVNWLPgtrgggsRARVGGLTLACAPGLAQPGASVRLAVR 276

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

32-252

6.44e-31

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 119.44 E-value: 6.44e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  32 DISLAVRAGETLALVGESGCGKsiTSL--ALMGLL-PASARIVSGEMHF----RRHDLrklsPREyanLRGseLAMIFQE 104
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGK--TTLlrAIAGLErPDSGRIRLGGEVLqdsaRGIFL----PPH---RRR--IGYVFQE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 105 PmtSLNPAFTLGDQLsEAVMRHqtlSRAEAMTVAL-QILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLI 183
Cdd:COG4148   86 A--RLFPHLSVRGNL-LYGRKR---APRAERRISFdEVVELLGI---GHLLDRRPATLSGGERQRVAIGRALLSSPRLLL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 184 ADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:COG4148  157 MDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

8-256

8.76e-31

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 122.18 E-value: 8.76e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSP 87
Cdd:COG4987  329 PGGPSLELEDVSFRYPGAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQ----SGSITLGGVDLRDLDE 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 reyANLRgSELAMIFQEPmtslnPAF--TLGDQLSEAVmrhQTLSRAEAMTValqiLEKVQIPAAEMRLK------VYPH 159
Cdd:COG4987  405 ---DDLR-RRIAVVPQRP-----HLFdtTLRENLRLAR---PDATDEELWAA----LERVGLGDWLAALPdgldtwLGEG 468

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 --QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLgVVAEVAQQVAVMYAG 237
Cdd:COG4987  469 grRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHRL-AGLERMDRILVLEDG 545

                        250
                 ....*....|....*....
gi 550714244 238 QVVEQGSVEAIFADPQHPY 256
Cdd:COG4987  546 RIVEQGTHEELLAQNGRYR 564

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

11-253

8.86e-31

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 116.89 E-value: 8.86e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGS--PVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMhfrRHDLRKLS- 86
Cdd:COG4525    2 SMLTVRHVSVRYPGGgqPQPALQDVSLTIESGEFVVALGASGCGKT-TLLNLIaGFLAPS----SGEI---TLDGVPVTg 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PreyanlrGSELAMIFQE----PMTSL--NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQ 160
Cdd:COG4525   74 P-------GADRGVVFQKdallPWLNVldNVAFGL---------RLRGVPKAERRARAEELLALVGLADFARR---RIWQ 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDlgvVAE---VAQQVAVM--Y 235
Cdd:COG4525  135 LSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS---VEEalfLATRLVVMspG 211

                        250       260       270
                 ....*....|....*....|....*....|
gi 550714244 236 AGQVVEQ------------GSVEAIFADPQ 253
Cdd:COG4525  212 PGRIVERleldfsrrflagEDARAIKSDPA 241

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

14-240

1.08e-30

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 115.05 E-value: 1.08e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEmhfrrhdlRKLSPREyan 92
Cdd:cd03226    1 RIENISFSYKKGT-EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIkESSGSILLNG--------KPIKAKE--- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGSELAMIFQEPmtslnpaftlGDQL-SEAVMRHQTLSR---AEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQR 168
Cdd:cd03226   69 -RRKSIGYVMQDV----------DYQLfTDSVREELLLGLkelDAGNEQAETVLKDLDLYALKER---HPLSLSGGQKQR 134

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:cd03226  135 LAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

11-239

1.56e-30

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 114.07 E-value: 1.56e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKfagspvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREy 90
Cdd:cd03215    3 PVLEVRGLSVK------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPA----SGEITLDGKPVTRRSPRD- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRGSelamifqepmtslnpAFTLGDQLSEAVMrhQTLSRAEAMTValqilekvqipaaemrlkvyPHQLSGGMRQRVM 170
Cdd:cd03215   72 AIRAGI---------------AYVPEDRKREGLV--LDLSVAENIAL--------------------SSLLSGGNQQKVV 114

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:cd03215  115 LARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182

3a0106s01

TIGR00968

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

29-267

2.47e-30

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 115.28 E-value: 2.47e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGL-LPASARIVsgemhFRRHDLRKLSPREyanlrgSELAMIFQEpmt 107
Cdd:TIGR00968  15 ALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLeQPDSGRIR-----LNGQDATRVHARD------RKIGFVFQH--- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  108 slnpaftlgdqlsEAVMRHQTLSRAEAMTvalqiLEKVQIPAAEMRLKV---------------YPHQLSGGMRQRVMIA 172
Cdd:TIGR00968  81 -------------YALFKHLTVRDNIAFG-----LEIRKHPKAKIKARVeellelvqleglgdrYPNQLSGGQRQRVALA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:TIGR00968 143 RALAVEPQVLLLDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHP 222

                         250
                  ....*....|....*
gi 550714244  253 QHPYTIGLMGSIPSL 267
Cdd:TIGR00968 223 ANPFVMSFLGEVNVL 237

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

5-261

2.47e-30

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 120.13 E-value: 2.47e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   5 PFKDSTPVLRLQNLNVKfAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRK 84
Cdd:COG3845  250 PAEPGEVVLEVENLSVR-DDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPA----SGSIRLDGEDITG 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  85 LSPREYANLRgseLAMIFQEPM-TSLNPAFT------LGDQLSEAVMRHQTLSRAEAMTVALQILEK--VQIPAAEMRLK 155
Cdd:COG3845  325 LSPRERRRLG---VAYIPEDRLgRGLVPDMSvaenliLGRYRRPPFSRGGFLDRKAIRAFAEELIEEfdVRTPGPDTPAR 401

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 vyphQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:COG3845  402 ----SLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMY 476

                        250       260
                 ....*....|....*....|....*.
gi 550714244 236 AGQVVeqGSVEAIFADPQhpyTIGLM 261
Cdd:COG3845  477 EGRIV--GEVPAAEATRE---EIGLL 497

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

10-251

6.55e-30

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 114.41 E-value: 6.55e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTslalmgLLpasaRIVSGEMH------------- 76
Cdd:COG1119    1 DPLLELRNVTVRRGGKTI--LDDISWTVKPGEHWAILGPNGAGKS-T------LL----SLITGDLPptygndvrlfger 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  77 FRRHDLRKLSPR-EYANlrgSELAMIFQEPMTSLN---PAF--TLGdqlseavmRHQTLSRAEAMTvALQILEKVQIPA- 149
Cdd:COG1119   68 RGGEDVWELRKRiGLVS---PALQLRFPRDETVLDvvlSGFfdSIG--------LYREPTDEQRER-ARELLELLGLAHl 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 150 AEMRLkvypHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQ 229
Cdd:COG1119  136 ADRPF----GTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGIT 211

                        250       260
                 ....*....|....*....|..
gi 550714244 230 QVAVMYAGQVVEQGSVEAIFAD 251
Cdd:COG1119  212 HVLLLKDGRVVAAGPKEEVLTS 233

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

7-264

8.37e-30

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 116.86 E-value: 8.37e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   7 KDSTPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLS 86
Cdd:PRK11607  14 KALTPLLEIRNLTKSFDGQHA--VDDVSLTIYKGEIFALLGASGCGKS----TLLRMLAGFEQPTAGQIMLDGVDLSHVP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PREyanlrgSELAMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMR 166
Cdd:PRK11607  88 PYQ------RPINMMFQS--YALFPHMTVEQNIAFG-LKQDKLPKAEIASRVNEMLGLVHMQEFAKR---KPHQLSGGQR 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVE 246
Cdd:PRK11607 156 QRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPE 235

                        250
                 ....*....|....*...
gi 550714244 247 AIFADPQHPYTIGLMGSI 264
Cdd:PRK11607 236 EIYEHPTTRYSAEFIGSV 253

PhnT

TIGR03258

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...

13-281

9.07e-30

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.

Pssm-ID: 132302 [Multi-domain] Cd Length: 362 Bit Score: 116.63 E-value: 9.07e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   13 LRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAriVSGEMHFRRHDLRKLSPREyan 92
Cdd:TIGR03258   6 IRIDHLRVAYGAN--TVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAG--LTGRIAIADRDLTHAPPHK--- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   93 lRGseLAMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIA 172
Cdd:TIGR03258  79 -RG--LALLFQN--YALFPHLKVEDNVAFG-LRAQKMPKADIAERVADALKLVGLGDAAAH---LPAQLSGGMQQRIAIA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEE-TGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:TIGR03258 150 RAIAIEPDVLLLDEPLSALDANIRANMREEIAALHEElPELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDA 229

                         250       260       270
                  ....*....|....*....|....*....|
gi 550714244  252 PQHPYTIGLMGSIPSLGVRKGQLSTIPGSV 281
Cdd:TIGR03258 230 PADGFAAEFLGAANILPAIALGITEAPGLV 259

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

13-243

9.32e-30

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 113.12 E-value: 9.32e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLlpasARIVSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03301    1 VELENVTKRFGN--VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGL----EEPTSGRIYIGGRDVTDLPPKD--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGseLAMIFQEpmTSLNPAFTLGDQLSEAV-MRHQtlSRAEamtvalqILEKVQiPAAEMrLKV------YPHQLSGGM 165
Cdd:cd03301   72 -RD--IAMVFQN--YALYPHMTVYDNIAFGLkLRKV--PKDE-------IDERVR-EVAEL-LQIehlldrKPKQLSGGQ 135

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03301  136 RQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213

PRK10619

histidine ABC transporter ATP-binding protein HisP;

29-255

1.10e-29

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 113.91 E-value: 1.10e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARIVSGEMHFR----RHDLRKLSPREYANLRGSELAMIF 102
Cdd:PRK10619  20 VLKGVSLQANAGDVISIIGSSGSGKS-TFLRCINFLekPSEGSIVVNGQTINlvrdKDGQLKVADKNQLRLLRTRLTMVF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 103 QEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIpaAEMRLKVYPHQLSGGMRQRVMIAMALINHPKLL 182
Cdd:PRK10619  99 QH--FNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGI--DERAQGKYPVHLSGGQQQRVSIARALAMEPEVL 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 183 IADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHP 255
Cdd:PRK10619 175 LFDEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSP 246

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

10-253

1.21e-29

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 113.15 E-value: 1.21e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPRE 89
Cdd:COG0410    1 MPMLEVENLHAGYGGIHV--LHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPR----SGSIRFDGEDITGLPPHR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANL--------RGselamIFQEpMTSL-N---PAFTLGDQLSEAvmrhqtlsraeamtvalQILEKVqipaAEM--RLK 155
Cdd:COG0410   75 IARLgigyvpegRR-----IFPS-LTVEeNlllGAYARRDRAEVR-----------------ADLERV----YELfpRLK 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 VYPHQ----LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQV 231
Cdd:COG0410  128 ERRRQragtLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRA 206

                        250       260
                 ....*....|....*....|..
gi 550714244 232 AVMYAGQVVEQGSVEAIFADPQ 253
Cdd:COG0410  207 YVLERGRIVLEGTAAELLADPE 228

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

12-248

1.57e-29

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 114.44 E-value: 1.57e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFrrhDLRKLSPREYA 91
Cdd:COG4152    1 MLELKGLTKRFGD--KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPD----SGEVLW---DGEPLDPEDRR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NL------RGselamifqepmtsLNPAFTLGDQLSEAVMRHQtLSRAEAMTVALQILEKVQIPAAEMRlKVypHQLSGGM 165
Cdd:COG4152   72 RIgylpeeRG-------------LYPKMKVGEQLVYLARLKG-LSKAEAKRRADEWLERLGLGDRANK-KV--EELSKGN 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVtIQAQILA-LLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:COG4152  135 QQKVQLIAALLHDPELLILDEPFSGLDP-VNVELLKdVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGS 212


                 ....
gi 550714244 245 VEAI 248
Cdd:COG4152  213 VDEI 216

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

13-251

4.67e-29

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 111.55 E-value: 4.67e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSpreYAN 92
Cdd:cd03251    1 VEFKNVTFRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKS----TLVNLIPRFYDVDSGRILIDGHDVRDYT---LAS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEPM---TSL--NPAFTLGDQLSEAVMRhqTLSRAEAMTVALQILEKVQIPAAEMRLKvyphqLSGGMRQ 167
Cdd:cd03251   74 LR-RQIGLVSQDVFlfnDTVaeNIAYGRPGATREEVEE--AARAANAHEFIMELPEGYDTVIGERGVK-----LSGGQRQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVaEVAQQVAVMYAGQVVEQGSVEA 247
Cdd:cd03251  146 RIAIARALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTI-ENADRIVVLEDGKIVERGTHEE 222


                 ....
gi 550714244 248 IFAD 251
Cdd:cd03251  223 LLAQ 226

cbiO

PRK13640

energy-coupling factor transporter ATPase;

25-260

6.53e-29

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 112.59 E-value: 6.53e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  25 SPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-----PASARIVSGemhfrrhdlRKLSPREYANLRgSELA 99
Cdd:PRK13640  18 SKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpddnPNSKITVDG---------ITLTAKTVWDIR-EKVG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 100 MIFQEPMTSLNPAfTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAemrLKVYPHQLSGGMRQRVMIAMALINHP 179
Cdd:PRK13640  88 IVFQNPDNQFVGA-TVGDDVAFG-LENRAVPRPEMIKIVRDVLADVGMLDY---IDSEPANLSGGQKQRVAIAGILAVEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 180 KLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGvVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIG 259
Cdd:PRK13640 163 KIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDID-EANMADQVLVLDDGKLLAQGSPVEIFSKVEMLKEIG 241


                 .
gi 550714244 260 L 260
Cdd:PRK13640 242 L 242

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

19-244

7.32e-29

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 111.48 E-value: 7.32e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFAgSP----VSVLEDISLAVRAGETLALVGESGCGKSITslalMGLLPASARIVSGEMHFRRHDLRKLSPREYANLr 94
Cdd:cd03249    5 NVSFR-YPsrpdVPILKGLSLTIPPGKTVALVGSSGCGKSTV----VSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQ- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 gseLAMIFQEPM---TSL--NPAFTLGDQLSEAVMRHQTLSRAEAMTVALQilEKVQIPAAEmrlkvYPHQLSGGMRQRV 169
Cdd:cd03249   79 ---IGLVSQEPVlfdGTIaeNIRYGKPDATDEEVEEAAKKANIHDFIMSLP--DGYDTLVGE-----RGSQLSGGQKQRI 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGS 244
Cdd:cd03249  149 AIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGT 220

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

29-298

1.13e-28

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 113.64 E-value: 1.13e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyanlrgSELAMIFQ----- 103
Cdd:PRK10851  17 VLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQT----SGHIRFHGTDVSRLHARD------RKVGFVFQhyalf 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 104 EPMTSL-NPAFTLgdqlsEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIAMALINHPKLL 182
Cdd:PRK10851  87 RHMTVFdNIAFGL-----TVLPRRERPNAAAIKAKVTQLLEMVQLAHLADR---YPAQLSGGQKQRVALARALAVEPQIL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 183 IADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGLMG 262
Cdd:PRK10851 159 LLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMG 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 550714244 263 SIPSL-GVRKG----------QLSTIP---GSVPL---PESMPQGCRFATRCP 298
Cdd:PRK10851 239 EVNRLqGTIRGgqfhvgahrwPLGYTPayqGPVDLflrPWEVDISRRTSLDSP 291

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

11-248

2.88e-28

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 114.35 E-value: 2.88e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKfagspvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREy 90
Cdd:COG1129  255 VVLEVEGLSVG------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPAD----SGEIRLDGKPVRIRSPRD- 323

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRGseLAMIfqeP----MTSLNPAFTLGDQLSEAVMRHQT----LSRAEAMTVALQILEKVQIPAAEMRLKVypHQLS 162
Cdd:COG1129  324 AIRAG--IAYV---PedrkGEGLVLDLSIRENITLASLDRLSrgglLDRRRERALAEEYIKRLRIKTPSPEQPV--GNLS 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 GGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVV-- 240
Cdd:COG1129  397 GGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDRILVMREGRIVge 475

                        250
                 ....*....|.
gi 550714244 241 ---EQGSVEAI 248
Cdd:COG1129  476 ldrEEATEEAI 486

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

13-249

4.17e-28

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 109.72 E-value: 4.17e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSItslalmgLLPASARI---VSGEMHFRRHDLRKLSPRE 89
Cdd:PRK11231   3 LRTENLTVGYGTKRI--LNDLSLSLPTGKITALIGPNGCGKST-------LLKCFARLltpQSGTVFLGDKPISMLSSRQ 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANlrgsELAMIFQEPMT------------SLNPAFTLGDQLSEAvmRHQTLSRAEAMTvalQILEKVQIPAAEmrlkvy 157
Cdd:PRK11231  74 LAR----RLALLPQHHLTpegitvrelvayGRSPWLSLWGRLSAE--DNARVNQAMEQT---RINHLADRRLTD------ 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 phqLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:PRK11231 139 ---LSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANG 214

                        250
                 ....*....|..
gi 550714244 238 QVVEQGSVEAIF 249
Cdd:PRK11231 215 HVMAQGTPEEVM 226

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

13-243

5.43e-28

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 108.14 E-value: 5.43e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAgsPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03269    1 LEVENVTKRFG--RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPD----SGEVLFDGKPLDIAARNRIGY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 L---RGselamifqepmtsLNPAFTLGDQLSeAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRLKvyphQLSGGMRQR 168
Cdd:cd03269   75 LpeeRG-------------LYPKMKVIDQLV-YLAQLKGLKKEEARRRIDEWLERLELsEYANKRVE----ELSKGNQQK 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03269  137 VQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

12-257

1.13e-27

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 108.46 E-value: 1.13e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGL--LPASARiVSGEMHFRRHDLRKLSPRE 89
Cdd:PRK14247   3 KIEIRDLKVSFGQ--VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLieLYPEAR-VSGEVYLDGQDIFKMDVIE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanLRgSELAMIFQEP----MTSLNPAFTLGDQLSEAVMrhqtlSRAEAMTVALQILEKVQI-PAAEMRLKVYPHQLSGG 164
Cdd:PRK14247  80 ---LR-RRVQMVFQIPnpipNLSIFENVALGLKLNRLVK-----SKKELQERVRWALEKAQLwDEVKDRLDAPAGKLSGG 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:PRK14247 151 QQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGP 228

                        250
                 ....*....|...
gi 550714244 245 VEAIFADPQHPYT 257
Cdd:PRK14247 229 TREVFTNPRHELT 241

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

13-253

2.13e-27

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 107.86 E-value: 2.13e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASArivsGEMHFrrhDLRKLS-Prey 90
Cdd:PRK11248   2 LQISHLYADYGGKPA--LEDINLTLESGELLVVLGPSGCGKT-TLLNLIaGFVPYQH----GSITL---DGKPVEgP--- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anlrGSELAMIFQE----PMTSLNPAFTLGDQLseavmrhQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMR 166
Cdd:PRK11248  69 ----GAERGVVFQNegllPWRNVQDNVAFGLQL-------AGVEKMQRLEIAHQMLKKVGLEGAEKR---YIWQLSGGQR 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMY--AGQVVEQ-- 242
Cdd:PRK11248 135 QRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSpgPGRVVERlp 214

                        250       260
                 ....*....|....*....|.
gi 550714244 243 ----------GSVEAIFADPQ 253
Cdd:PRK11248 215 lnfarrfvagESSRSIKSDPQ 235

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

19-244

2.17e-27

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 112.57 E-value: 2.17e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFA-GSPVSVLEDISLAVRAGETLALVGESGCGKS-ITSLaLMGLLPASA-RI-VSGemhfrrHDLRKLSPREyanLR 94
Cdd:COG1132  344 NVSFSyPGDRPVLKDISLTIPPGETVALVGPSGSGKStLVNL-LLRFYDPTSgRIlIDG------VDIRDLTLES---LR 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 gSELAMIFQEPM---TSL--NPAFTLGDQLSEAVMrhqtlsraEAMTVAlQILEKVqipaaeMRLkvyPHQ--------- 160
Cdd:COG1132  414 -RQIGVVPQDTFlfsGTIreNIRYGRPDATDEEVE--------EAAKAA-QAHEFI------EAL---PDGydtvvgerg 474

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 --LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMYAGQ 238
Cdd:COG1132  475 vnLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLSTIRN-ADRILVLDDGR 551


                 ....*.
gi 550714244 239 VVEQGS 244
Cdd:COG1132  552 IVEQGT 557

drrA

TIGR01188

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...

30-246

2.71e-27

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]

Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 108.63 E-value: 2.71e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASA--RIVSGemhfrrHDLrklsPREYANLRGSeLAMIFQEPmt 107
Cdd:TIGR01188   9 VDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSgtARVAG------YDV----VREPRKVRRS-IGIVPQYA-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  108 SLNPAFTlGDQLSEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRLKVYphqlSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:TIGR01188  76 SVDEDLT-GRENLEMMGRLYGLPKDEAEERAEELLELFELgEAADRPVGTY----SGGMRRRLDIAASLIHQPDVLFLDE 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  187 PTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVE 246
Cdd:TIGR01188 151 PTTGLDPRTRRAIWDYIRALKEE-GVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPE 209

FtsE

TIGR02673

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...

12-238

3.06e-27

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]

Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 106.18 E-value: 3.06e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   12 VLRLQNLNVKFAGsPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREYA 91
Cdd:TIGR02673   1 MIEFHNVSKAYPG-GVAALHDVSLHIRKGEFLFLTGPSGAGKT----TLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   92 NLRGSeLAMIFQE-----PMTSL-NPAFTLGDQLSEAVMRHQTLSRaeamtvalqILEKVQIpaaEMRLKVYPHQLSGGM 165
Cdd:TIGR02673  76 LLRRR-IGVVFQDfrllpDRTVYeNVALPLEVRGKKEREIQRRVGA---------ALRQVGL---EHKADAFPEQLSGGE 142

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244  166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:TIGR02673 143 QQRVAIARAIVNSPPLLLADEPTGNLDPDLSERILDLLKRLNKR-GTTVIVATHDLSLVDRVAHRVIILDDGR 214

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

45-264

3.50e-27

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 108.74 E-value: 3.50e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   45 LVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPreyaNLRGseLAMIFQEpmTSLNPAFTLGDQLSEAvM 124
Cdd:TIGR01187   1 LLGPSGCGKT----TLLRLLAGFEQPDSGSIMLDGEDVTNVPP----HLRH--INMVFQS--YALFPHMTVEENVAFG-L 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  125 RHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLN 204
Cdd:TIGR01187  68 KMRKVPRAEIKPRVLEALRLVQL---EEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELK 144

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  205 TLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGLMGSI 264
Cdd:TIGR01187 145 TIQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEI 204

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

13-229

5.71e-27

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 105.64 E-value: 5.71e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARiVSGEMHFRRHDLRKLSPREyan 92
Cdd:COG4136    2 LSLENLTITLGGRPL--LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAFS-ASGEVLLNGRRLTALPAEQ--- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGseLAMIFQEPMtsLNPAFTLGDQLSEAVMRhqTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIA 172
Cdd:COG4136   76 -RR--IGILFQDDL--LFPHLSVGENLAFALPP--TIGRAQRRARVEQALEEAGLAGFADR---DPATLSGGQRARVALL 145

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQ 229
Cdd:COG4136  146 RALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAAGR 202

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

13-244

9.79e-27

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 110.58 E-value: 9.79e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSpreYAN 92
Cdd:TIGR02203 331 VEFRNVTFRYPGRDRPALDSISLVIEPGETVALVGRSGSGKS----TLVNLIPRFYEPDSGQILLDGHDLADYT---LAS 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   93 LRgSELAMIFQEPM-----TSLNPAFTLGDQLSEAVMRhQTLSRAEAMTVALQILEKVQIPAAEMRLKvyphqLSGGMRQ 167
Cdd:TIGR02203 404 LR-RQVALVSQDVVlfndtIANNIAYGRTEQADRAEIE-RALAAAYAQDFVDKLPLGLDTPIGENGVL-----LSGGQRQ 476

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244  168 RVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTavLMITHDLGVVaEVAQQVAVMYAGQVVEQGS 244
Cdd:TIGR02203 477 RLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQGRTT--LVIAHRLSTI-EKADRIVVMDDGRIVERGT 550

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

8-260

3.06e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 105.22 E-value: 3.06e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   8 DSTPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHdlrKLSP 87
Cdd:PRK13648   3 DKNSIIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVK----SGEIFYNNQ---AITD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANLRgSELAMIFQEP-------MTSLNPAFTLGDQLSEAVMRHQTLSraeamtvalQILEKVQIPAaemRLKVYPHQ 160
Cdd:PRK13648  76 DNFEKLR-KHIGIVFQNPdnqfvgsIVKYDVAFGLENHAVPYDEMHRRVS---------EALKQVDMLE---RADYEPNA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEvAQQVAVMYAGQVV 240
Cdd:PRK13648 143 LSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVY 221

                        250       260
                 ....*....|....*....|
gi 550714244 241 EQGSVEAIFADPQHPYTIGL 260
Cdd:PRK13648 222 KEGTPTEIFDHAEELTRIGL 241

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

27-225

3.26e-26

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 104.09 E-value: 3.26e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYANLRGSELAMIFQEPM 106
Cdd:PRK10584  23 LSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGS----SGEVSLVGQPLHQMDEEARAKLRAKHVGFVFQSFM 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 107 --TSLNpafTLGDQLSEAVMRHQtlSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIA 184
Cdd:PRK10584  99 liPTLN---ALENVELPALLRGE--SSRQSRNGAKALLEQLGL---GKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 550714244 185 DEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVA 225
Cdd:PRK10584 171 DEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAA 211

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

11-251

3.97e-26

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 108.35 E-value: 3.97e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   11 PVLRLQNLNVKFAG---SPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRH----DLR 83
Cdd:TIGR03269 278 PIIKVRNVSKRYISvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPT----SGEVNVRVGdewvDMT 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   84 KLSPreyaNLRGSE---LAMIFQEpmTSLNPAFTLGDQLSEAVmrHQTLSRAEAMTVALQILEKVQI--PAAEMRLKVYP 158
Cdd:TIGR03269 354 KPGP----DGRGRAkryIGILHQE--YDLYPHRTVLDNLTEAI--GLELPDELARMKAVITLKMVGFdeEKAEEILDKYP 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:TIGR03269 426 DELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGK 505

                         250
                  ....*....|...
gi 550714244  239 VVEQGSVEAIFAD 251
Cdd:TIGR03269 506 IVKIGDPEEIVEE 518

OpuBA

COG1125

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

14-263

5.19e-26

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 105.17 E-value: 5.19e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARI-VSGEmhfrrhDLRKLSPREy 90
Cdd:COG1125    3 EFENVTKRYPDGTV-AVDDLSLTIPAGEFTVLVGPSGCGKT-TTLRMINRLiePTSGRIlIDGE------DIRDLDPVE- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anLRGSelamI---FQEpmTSLNPAFTLGDQLSeAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRlKVYPHQLSGGMRQ 167
Cdd:COG1125   74 --LRRR----IgyvIQQ--IGLFPHMTVAENIA-TVPRLLGWDKERIRARVDELLELVGLDPEEYR-DRYPHELSGGQQQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALD-VT---IQAQILALlntlKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:COG1125  144 RVGVARALAADPPILLMDEPFGALDpITreqLQDELLRL----QRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYD 219

                        250       260
                 ....*....|....*....|
gi 550714244 244 SVEAIFADPQHPYTIGLMGS 263
Cdd:COG1125  220 TPEEILANPANDFVADFVGA 239

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

9-264

7.15e-26

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 104.41 E-value: 7.15e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKS--ITSLALM-----GLLPASARIVSGEMHFRRHD 81
Cdd:PRK14271  18 AAPAMAAVNLTLGFAGK--TVLDQVSMGFPARAVTSLMGPTGSGKTtfLRTLNRMndkvsGYRYSGDVLLGGRSIFNYRD 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  82 LRKLSPReyanlrgseLAMIFQEPmtslNP-AFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRLKVYPH 159
Cdd:PRK14271  96 VLEFRRR---------VGMLFQRP----NPfPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLwDAVKDRLSDSPF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:PRK14271 163 RLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRL 240

                        250       260
                 ....*....|....*....|....*....
gi 550714244 240 VEQGSVEAIFADPQHP----YTIGLMGSI 264
Cdd:PRK14271 241 VEEGPTEQLFSSPKHAetarYVAGLSGDV 269

cbiO

PRK13642

energy-coupling factor transporter ATPase;

12-260

1.48e-25

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 103.63 E-value: 1.48e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAG-SPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVsgemhfrRHDLRKLSPREY 90
Cdd:PRK13642   4 ILEVENLVFKYEKeSDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKV-------KIDGELLTAENV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRgSELAMIFQEPMTSLNPAfTLGDQLS-----EAVMRHQTLSRAEAMTVALQILE-KVQIPAaemrlkvyphQLSGG 164
Cdd:PRK13642  77 WNLR-RKIGMVFQNPDNQFVGA-TVEDDVAfgmenQGIPREEMIKRVDEALLAVNMLDfKTREPA----------RLSGG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGS 244
Cdd:PRK13642 145 QKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAA 223

                        250
                 ....*....|....*.
gi 550714244 245 VEAIFADPQHPYTIGL 260
Cdd:PRK13642 224 PSELFATSEDMVEIGL 239

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

17-262

1.65e-25

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 102.61 E-value: 1.65e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  17 NLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGL--LPASARiVSGEMHFRRHDL--RKLSPREYAN 92
Cdd:PRK14267   9 NLRVYYGSN--HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLleLNEEAR-VEGEVRLFGRNIysPDVDPIEVRR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgsELAMIFQEPmtSLNPAFTLGDQLSEAVMRHQTL-SRAEAMTVALQILEKVQI-PAAEMRLKVYPHQLSGGMRQRVM 170
Cdd:PRK14267  86 ----EVGMVFQYP--NPFPHLTIYDNVAIGVKLNGLVkSKKELDERVEWALKKAALwDEVKDRLNDYPSNLSGGQRQRLV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:PRK14267 160 IARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFE 237

                        250
                 ....*....|....*.
gi 550714244 251 DPQHP----YTIGLMG 262
Cdd:PRK14267 238 NPEHEltekYVTGALG 253

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

12-251

2.11e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 103.00 E-value: 2.11e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSpVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIvsgemhfrrhdLRKLSPREY 90
Cdd:PRK13636   5 ILKVEELNYNYSDG-THALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILkPSSGRI-----------LFDGKPIDY 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 A-----NLRGSeLAMIFQEPMTSLNPAFTLGDqLSEAVMRHQtLSRAEAMTVALQILEKVQIPaaemRLKVYP-HQLSGG 164
Cdd:PRK13636  73 SrkglmKLRES-VGMVFQDPDNQLFSASVYQD-VSFGAVNLK-LPEDEVRKRVDNALKRTGIE----HLKDKPtHCLSFG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:PRK13636 146 QKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGN 225


                 ....*..
gi 550714244 245 VEAIFAD 251
Cdd:PRK13636 226 PKEVFAE 232

oligo_HPY

pfam08352

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...

240-304

2.60e-25

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.

Pssm-ID: 400588 [Multi-domain] Cd Length: 65 Bit Score: 96.70 E-value: 2.60e-25

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244  240 VEQGSVEAIFADPQHPYTIGLMGSIPSLGVRKGQLSTIPGSVPLPESMPQGCRFATRCPFAQTRC 304
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDPPKRPLYTIPGNVPSLLELPEGCPFAPRCPFATEEC 65

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

27-239

3.06e-25

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 100.95 E-value: 3.06e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREYANLRGSeLAMIFQEpm 106
Cdd:cd03292   14 TAALDGINISISAGEFVFLVGPSGAGKS----TLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRRK-IGVVFQD-- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 107 TSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:cd03292   87 FRLLPDRNVYENVAFA-LEVTGVPPREIRKRVPAALELVGL---SHKHRALPAELSGGEQQRVAIARAIVNSPTILIADE 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 550714244 187 PTTALDVTIQAQILALLNTLkEETGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:cd03292  163 PTGNLDPDTTWEIMNLLKKI-NKAGTTVVVATHAKELVDTTRHRVIALERGKL 214

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

10-264

3.12e-25

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 104.26 E-value: 3.12e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSP- 87
Cdd:PRK09452  12 SPLVELRGISKSFDGKEV--ISNLDLTINNGEFLTLLGPSGCGKT-TVLRLIaGFETPD----SGRIMLDGQDITHVPAe 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANlrgselaMIFQE----P-MTSL-NPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIPA-AEMRlkvyPHQ 160
Cdd:PRK09452  85 NRHVN-------TVFQSyalfPhMTVFeNVAFGL---------RMQKTPAAEITPRVMEALRMVQLEEfAQRK----PHQ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:PRK09452 145 LSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIE 224

                        250       260
                 ....*....|....*....|....
gi 550714244 241 EQGSVEAIFADPQHPYTIGLMGSI 264
Cdd:PRK09452 225 QDGTPREIYEEPKNLFVARFIGEI 248

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

10-240

4.96e-25

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 105.96 E-value: 4.96e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKF-AG-SPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSP 87
Cdd:PRK10535   2 TALLELKDIRRSYpSGeEQVEVLKGISLDIYAGEMVAIVGASGSGKS----TLMNILGCLDKPTSGTYRVAGQDVATLDA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANLRGSELAMIFQE--PMTSLN-------PAFTLGdqlseaVMRHQTLSRAEAMTVALQILEkvqipaaemRLKVYP 158
Cdd:PRK10535  78 DALAQLRREHFGFIFQRyhLLSHLTaaqnvevPAVYAG------LERKQRLLRAQELLQRLGLED---------RVEYQP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEvAQQVAVMYAGQ 238
Cdd:PRK10535 143 SQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDR-GHTVIIVTHDPQVAAQ-AERVIEIRDGE 220


                 ..
gi 550714244 239 VV 240
Cdd:PRK10535 221 IV 222

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

32-256

5.12e-25

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 103.27 E-value: 5.12e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   32 DISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIV-SGEMHFRRHDLRKLSPREYAnlrgseLAMIFQEpmTSL 109
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTrPDEGEIVlNGRTLFDSRKGIFLPPEKRR------IGYVFQE--ARL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  110 NPAFTLGDQLSEAVMR---HQTLSRAEAMTVALQIlekvqipaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:TIGR02142  87 FPHLSVRGNLRYGMKRarpSERRISFERVIELLGI---------GHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDE 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  187 PTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPY 256
Cdd:TIGR02142 158 PLAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW 227

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

30-254

7.28e-25

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 100.23 E-value: 7.28e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   30 LEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPreyanlrgsELAMIFQEpmTSL 109
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKS----TLLNLISGLAQPTSGGVILEGKQITEPGP---------DRMVVFQN--YSL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  110 NPAFTLGDQLSEAVMR-HQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIAMALINHPKLLIADEPT 188
Cdd:TIGR01184  66 LPWLTVRENIALAVDRvLPDLSKSERRAIVEEHIALVGLTEAADK---RPGQLSGGMKQRVAIARALSIRPKVLLLDEPF 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244  189 TALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV-EAIFADPQH 254
Cdd:TIGR01184 143 GALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQIlEVPFPRPRD 209

galliderm_ABC

TIGR03740

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...

13-245

7.45e-25

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.

Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 100.17 E-value: 7.45e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   13 LRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFRRHDLRKL-----S 86
Cdd:TIGR03740   1 LETKNLSKRFGKQ--TAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILrPTSGEIIFDGHPWTRKDLHKIgslieS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   87 PREYANLRGSELAMIfqepmtslnpaftlgdqlsEAVMRHQTLSRAEamtvalQILEKVQIPAAEmrlKVYPHQLSGGMR 166
Cdd:TIGR03740  79 PPLYENLTARENLKV-------------------HTTLLGLPDSRID------EVLNIVDLTNTG---KKKAKQFSLGMK 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  167 QRVMIAMALINHPKLLIADEPTTALD-VTIQaQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:TIGR03740 131 QRLGIAIALLNHPKLLILDEPTNGLDpIGIQ-ELRELIRSFPEQ-GITVILSSHILSEVQQLADHIGIISEGVLGYQGKI 208

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

7-253

9.72e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 101.22 E-value: 9.72e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   7 KDSTPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFRRHDLRKL 85
Cdd:PRK13632   2 KNKSVMIKVENVSFSYPNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLkPQSGEIKIDGITISKENLKEI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SpreyanlrgSELAMIFQepmtslNP-------------AFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIpaaEM 152
Cdd:PRK13632  82 R---------KKIGIIFQ------NPdnqfigatveddiAFGL---------ENKKVPPKKMKDIIDDLAKKVGM---ED 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 153 RLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGvvaEV--AQQ 230
Cdd:PRK13632 135 YLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMD---EAilADK 211

                        250       260
                 ....*....|....*....|...
gi 550714244 231 VAVMYAGQVVEQGSVEAIFADPQ 253
Cdd:PRK13632 212 VIVFSEGKLIAQGKPKEILNNKE 234

PRK14239

phosphate transporter ATP-binding protein; Provisional

9-257

1.45e-24

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 100.24 E-value: 1.45e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFagSPVSVLEDISLAVRAGETLALVGESGCGKS--ITSLALMG-LLPASAriVSGEMHFRRHDLrkL 85
Cdd:PRK14239   2 TEPILQVSDLSVYY--NKKKALNSVSLDFYPNEITALIGPSGSGKStlLRSINRMNdLNPEVT--ITGSIVYNGHNI--Y 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPR-EYANLRgSELAMIFQEPmtslNP-AFTLGDQLS-----EAVMRHQTLSRA-EAMTVALQILEKVQipaaeMRLKVY 157
Cdd:PRK14239  76 SPRtDTVDLR-KEIGMVFQQP----NPfPMSIYENVVyglrlKGIKDKQVLDEAvEKSLKGASIWDEVK-----DRLHDS 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:PRK14239 146 ALGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD--YTMLLVTRSMQQASRISDRTGFFLDG 223

                        250       260
                 ....*....|....*....|
gi 550714244 238 QVVEQGSVEAIFADPQHPYT 257
Cdd:PRK14239 224 DLIEYNDTKQMFMNPKHKET 243

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

40-243

2.93e-24

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 98.14 E-value: 2.93e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  40 GETLALVGESGCGKSITSLALMGLL-PASARIV-SGEMHFrrhDLRK---LSPREyanlRGseLAMIFQEpmTSLNPAFT 114
Cdd:cd03297   23 EEVTGIFGASGAGKSTLLRCIAGLEkPDGGTIVlNGTVLF---DSRKkinLPPQQ----RK--IGLVFQQ--YALFPHLN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 115 LGDQLSEAVMRH---QTLSRAEAMTVALQIlekvqipaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTAL 191
Cdd:cd03297   92 VRENLAFGLKRKrnrEDRISVDELLDLLGL---------DHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 550714244 192 DVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03297  163 DRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

15-243

3.43e-24

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 98.43 E-value: 3.43e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyanLR 94
Cdd:cd03245    5 FRNVSFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPT----SGSVLLDGTDIRQLDPAD---LR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 gSELAMIFQEPMT---SLNPAFTLGDQLS--EAVMRHQTLSRAEAMT------VALQILEKVQipaaemrlkvyphQLSG 163
Cdd:cd03245   78 -RNIGYVPQDVTLfygTLRDNITLGAPLAddERILRAAELAGVTDFVnkhpngLDLQIGERGR-------------GLSG 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVaEVAQQVAVMYAGQVVEQG 243
Cdd:cd03245  144 GQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLG--DKTLIIITHRPSLL-DLVDRIIVMDSGRIVADG 220

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

28-257

3.69e-24

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 99.35 E-value: 3.69e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  28 SVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPA--SARIVSGEMHFRRHDLRKLsprEYANLRgSELAMIFQEP 105
Cdd:PRK14246  24 AILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIydSKIKVDGKVLYFGKDIFQI---DAIKLR-KEVGMVFQQP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 106 mtSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIA 184
Cdd:PRK14246 100 --NPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLwKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLM 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 185 DEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYT 257
Cdd:PRK14246 178 DEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELT 248

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

13-249

4.02e-24

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 98.76 E-value: 4.02e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKfagspvSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivsGEMHFRRHDLRKLSPREYA 91
Cdd:COG4138    1 LQLNDVAVA------GRLGPISAQVNAGELIHLIGPNGAGKS-TLLARMaGLLPGQ-----GEILLNGRPLSDWSAAELA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRgselAMIFQEPMTSLN-PAF---TLGdqlseavmRHQTLSRAEAMTVALQILEKVQIPAAEMRLKvypHQLSGGMRQ 167
Cdd:COG4138   69 RHR----AYLSQQQSPPFAmPVFqylALH--------QPAGASSEAVEQLLAQLAEALGLEDKLSRPL---TQLSGGEWQ 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMAL------IN-HPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:COG4138  134 RVRLAAVLlqvwptINpEGQLLLLDEPMNSLDVAQQAALDRLLRELCQQ-GITVVMSSHDLNHTLRHADRVWLLKQGKLV 212


                 ....*....
gi 550714244 241 EQGSVEAIF 249
Cdd:COG4138  213 ASGETAEVM 221

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

13-246

7.40e-24

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 97.83 E-value: 7.40e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLlPASaRIVSGEMHFRRHDLRKLSPREYAN 92
Cdd:COG0396    1 LEIKNLHVSVEGKEI--LKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGH-PKY-EVTSGSILLDGEDILELSPDERAR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LrGseLAMIFQEPmtslnPAF---TLGDQLSEAV--MRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHqLSGGMRQ 167
Cdd:COG0396   77 A-G--IFLAFQYP-----VEIpgvSVSNFLRTALnaRRGEELSAREFLKLLKEKMKELGLDEDFLDRYVNEG-FSGGEKK 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIA-MALINhPKLLIADEPTTALDvtIQA-QILA-LLNTLKEEtGTAVLMITHDLGVVAEV-AQQVAVMYAGQVVEQG 243
Cdd:COG0396  148 RNEILqMLLLE-PKLAILDETDSGLD--IDAlRIVAeGVNKLRSP-DRGILIITHYQRILDYIkPDFVHVLVDGRIVKSG 223


                 ...
gi 550714244 244 SVE 246
Cdd:COG0396  224 GKE 226

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

16-244

8.80e-24

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 101.96 E-value: 8.80e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  16 QNLNVKFAGSPVSVlEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARI-VSGEmhfrrhDLRKLSpreYAN 92
Cdd:PRK13657 338 DDVSFSYDNSRQGV-EDVSFEAKPGQTVAIVGPTGAGKS-TLINLLQRVfdPQSGRIlIDGT------DIRTVT---RAS 406

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRGSeLAMIFQEPMTsLNPafTLGDQL-------SEAVMRhQTLSRAEAMTVALQILEKVQIPAAEMRLkvyphQLSGGM 165
Cdd:PRK13657 407 LRRN-IAVVFQDAGL-FNR--SIEDNIrvgrpdaTDEEMR-AAAERAQAHDFIERKPDGYDTVVGERGR-----QLSGGE 476

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVlmITHDLGVVAEvAQQVAVMYAGQVVEQGS 244
Cdd:PRK13657 477 RQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFI--IAHRLSTVRN-ADRILVFDNGRVVESGS 552

ProV

COG4175

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

32-256

1.39e-23

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 99.79 E-value: 1.39e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  32 DISLAVRAGETLALVGESGCGKSitSL--ALMGLLPASArivsGEMHFRRHDLRKLSPREYANLRGSELAMIFQE----P 105
Cdd:COG4175   45 DASFDVEEGEIFVIMGLSGSGKS--TLvrCLNRLIEPTA----GEVLIDGEDITKLSKKELRELRRKKMSMVFQHfallP 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 106 -MTSL-NPAFTLgdQLseavmrhQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIAMALINHPKLLI 183
Cdd:COG4175  119 hRTVLeNVAFGL--EI-------QGVPKAERRERAREALELVGLAGWEDS---YPDELSGGMQQRVGLARALATDPDILL 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 184 ADEPTTALDVTI----QAQILALLNTLKEetgTAVLmITHDLgvvAE---VAQQVAVMYAGQVVEQGSVEAIFADPQHPY 256
Cdd:COG4175  187 MDEAFSALDPLIrremQDELLELQAKLKK---TIVF-ITHDL---DEalrLGDRIAIMKDGRIVQIGTPEEILTNPANDY 259

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

30-256

1.80e-23

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 99.72 E-value: 1.80e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSiTSLALMGLLPASARivsGEMHFRRHDLRKLSPREYANLRGSELAMIFQEpmTSL 109
Cdd:PRK10070  44 VKDASLAIEEGEIFVIMGLSGSGKS-TMVRLLNRLIEPTR---GQVLIDGVDIAKISDAELREVRRKKIAMVFQS--FAL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 110 NPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTT 189
Cdd:PRK10070 118 MPHMTVLDNTAFG-MELAGINAEERREKALDALRQVGL---ENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFS 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 190 ALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPY 256
Cdd:PRK10070 194 ALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDY 260

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

13-239

2.51e-23

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 94.59 E-value: 2.51e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMhfrrhDLRKLSPREYa 91
Cdd:cd03246    1 LEVENVSFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLrPTSGRVRLDGA-----DISQWDPNEL- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 nlrGSELAMIFQEpmtslnpaftlgDQLSEAvmrhqtlsraeamTVALQILekvqipaaemrlkvyphqlSGGMRQRVMI 171
Cdd:cd03246   75 ---GDHVGYLPQD------------DELFSG-------------SIAENIL-------------------SGGQRQRLGL 107

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 172 AMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVlMITHDLGVVAEvAQQVAVMYAGQV 239
Cdd:cd03246  108 ARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAGATRI-VIAHRPETLAS-ADRILVLEDGRV 173

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

13-244

2.57e-23

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 96.02 E-value: 2.57e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03244    3 IEFKNVSLRYRPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELS----SGSILIDGVDISKIGLHD--- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEPMT-------SLNPaftlGDQLSEAvMRHQTLSRAeamtvalQILEKVQIPAA--EMRLKVYPHQLSG 163
Cdd:cd03244   76 LR-SRISIIPQDPVLfsgtirsNLDP----FGEYSDE-ELWQALERV-------GLKEFVESLPGglDTVVEEGGENLSV 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILallNTLKEE-TGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQ 242
Cdd:cd03244  143 GQRQLLCLARALLRKSKILVLDEATASVDPETDALIQ---KTIREAfKDCTVLTIAHRLDTIID-SDRILVLDKGRVVEF 218


                 ..
gi 550714244 243 GS 244
Cdd:cd03244  219 DS 220

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

13-262

3.80e-23

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 98.25 E-value: 3.80e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARI-VSGEmhfrrhDLRKLSpre 89
Cdd:PRK11432   7 VVLKNITKRFGSN--TVIDNLNLTIKQGTMVTLLGPSGCGKT-TVLRLVAGLekPTEGQIfIDGE------DVTHRS--- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanLRGSELAMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRV 169
Cdd:PRK11432  75 ---IQQRDICMVFQS--YALFPHMSLGENVGYG-LKMLGVPKEERKQRVKEALELVDLAGFEDR---YVDQISGGQQQRV 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIF 249
Cdd:PRK11432 146 ALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELY 225

                        250
                 ....*....|...
gi 550714244 250 ADPQHPYTIGLMG 262
Cdd:PRK11432 226 RQPASRFMASFMG 238

cbiO

PRK13650

energy-coupling factor transporter ATPase;

30-260

4.86e-23

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 96.72 E-value: 4.86e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAR--IVSGEmhfrrhdlrKLSPREYANLRgSELAMIFQEPMT 107
Cdd:PRK13650  23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGqiIIDGD---------LLTEENVWDIR-HKIGMVFQNPDN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 SLNPAfTLGDQLSEAvMRHQTLSRAEAMTVALQILEKVQIPAAEMRlkvYPHQLSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:PRK13650  93 QFVGA-TVEDDVAFG-LENKGIPHEEMKERVNEALELVGMQDFKER---EPARLSGGQKQRVAIAGAVAMRPKIIILDEA 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 188 TTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAeVAQQVAVMYAGQVVEQGSVEAIFADPQHPYTIGL 260
Cdd:PRK13650 168 TSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRELFSRGNDLLQLGL 239

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

19-250

6.06e-23

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 95.37 E-value: 6.06e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFAGSP-VSVLEDISLAVRAGETLALVGESGCGKSitslALMGLL-----PASARI-VSGemhfrrHDLRKLSpreYA 91
Cdd:cd03253    5 NVTFAYDPgRPVLKDVSFTIPAGKKVAIVGPSGSGKS----TILRLLfrfydVSSGSIlIDG------QDIREVT---LD 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRgSELAMIFQEpmTSL-------NPAFTLGDQLSEAVMrhqtlsraEAMTVAlQILEKV-QIPAA------EMRLKvy 157
Cdd:cd03253   72 SLR-RAIGVVPQD--TVLfndtigyNIRYGRPDATDEEVI--------EAAKAA-QIHDKImRFPDGydtivgERGLK-- 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 phqLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeeTGTAVLMITHDLGVVAEvAQQVAVMYAG 237
Cdd:cd03253  138 ---LSGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVS--KGRTTIVIAHRLSTIVN-ADKIIVLKDG 211

                        250
                 ....*....|...
gi 550714244 238 QVVEQGSVEAIFA 250
Cdd:cd03253  212 RIVERGTHEELLA 224

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

13-243

6.74e-23

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 94.59 E-value: 6.74e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03268    1 LKTNDLTKTYGKKRV--LDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPD----SGEITFDGKSYQKNIEAL--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgSELAMIFQEPmtSLNPAFTLGDQLSEAVMRHQtLSRAEAMtvalQILEKVQIPAAEmRLKVypHQLSGGMRQRVMIA 172
Cdd:cd03268   72 ---RRIGALIEAP--GFYPNLTARENLRLLARLLG-IRKKRID----EVLDVVGLKDSA-KKKV--KGFSLGMKQRLGIA 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03268  139 LALLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208

cbiO

PRK13637

energy-coupling factor transporter ATPase;

13-260

7.24e-23

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 96.27 E-value: 7.24e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLN-VKFAGSPVS--VLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARI-VSG----EMHFRRHDLR 83
Cdd:PRK13637   3 IKIENLThIYMEGTPFEkkALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLkPTSGKIiIDGvditDKKVKLSDIR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  84 KlspreyanlrgsELAMIFQEPMTSL-------NPAF---TLGDQLSEAVMRHQtlsraEAMtvalqilEKVQIPAAEMR 153
Cdd:PRK13637  83 K------------KVGLVFQYPEYQLfeetiekDIAFgpiNLGLSEEEIENRVK-----RAM-------NIVGLDYEDYK 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 154 LKVyPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAV 233
Cdd:PRK13637 139 DKS-PFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIV 217

                        250       260
                 ....*....|....*....|....*..
gi 550714244 234 MYAGQVVEQGSVEAIFADPQHPYTIGL 260
Cdd:PRK13637 218 MNKGKCELQGTPREVFKEVETLESIGL 244

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

30-260

1.46e-22

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 95.47 E-value: 1.46e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEM----HFRRHDLRKLSPReyanlrgseLAMIFQE 104
Cdd:PRK13634  23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLqPTSGTVTIGERvitaGKKNKKLKPLRKK---------VGIVFQF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 105 PMTSLnpaftlgdqLSEAVMRHQT-------LSRAEAMTVALQILEKVQIPaaEMRLKVYPHQLSGGMRQRVMIAMALIN 177
Cdd:PRK13634  94 PEHQL---------FEETVEKDICfgpmnfgVSEEDAKQKAREMIELVGLP--EELLARSPFELSGGQMRRVAIAGVLAM 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 178 HPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQHPYT 257
Cdd:PRK13634 163 EPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDELEA 242


                 ...
gi 550714244 258 IGL 260
Cdd:PRK13634 243 IGL 245

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

32-243

1.62e-22

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 93.71 E-value: 1.62e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  32 DISLAVRAGETLALVGESGCGKSiTSLALMG--LLPASARIVSGEMhfrrhDLRKLSPREyanlrgSELAMIFQEpmTSL 109
Cdd:cd03298   16 HFDLTFAQGEITAIVGPSGSGKS-TLLNLIAgfETPQSGRVLINGV-----DVTAAPPAD------RPVSMLFQE--NNL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 110 NPAFTLGDQLSEAVMRHQTLSRAEAMTVAlQILEKVQIPAAEMRLkvyPHQLSGGMRQRVMIAMALINHPKLLIADEPTT 189
Cdd:cd03298   82 FAHLTVEQNVGLGLSPGLKLTAEDRQAIE-VALARVGLAGLEKRL---PGELSGGERQRVALARVLVRDKPVLLLDEPFA 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 550714244 190 ALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03298  158 ALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

28-253

2.05e-22

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 94.76 E-value: 2.05e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  28 SVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLrKLSPREYANLRgSELAMIFQEPMT 107
Cdd:PRK13639  16 EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPT----SGEVLIKGEPI-KYDKKSLLEVR-KTVGIVFQNPDD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 SLNpAFTLGDQLSEAVMrHQTLSRAEAMTVALQILEKVQIPAAEmrlKVYPHQLSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:PRK13639  90 QLF-APTVEEDVAFGPL-NLGLSKEEVEKRVKEALKAVGMEGFE---NKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEP 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 188 TTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQ 253
Cdd:PRK13639 165 TSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIE 229

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

34-248

2.16e-22

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 93.88 E-value: 2.16e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  34 SLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDLRKLSPREyanlrgSELAMIFQEpmTSLNPA 112
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKS-TLLNLIaGFLTPA----SGSLTLNGQDHTTTPPSR------RPVSMLFQE--NNLFSH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 113 FTLGDQLSEAVMRHQTLSRAEAMTVAlQILEKVQIPAAEMRLkvyPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALD 192
Cdd:PRK10771  86 LTVAQNIGLGLNPGLKLNAAQREKLH-AIARQMGIEDLLARL---PGQLSGGQRQRVALARCLVREQPILLLDEPFSALD 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 193 VTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:PRK10771 162 PALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

27-243

2.68e-22

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 93.55 E-value: 2.68e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARI-VSGEMHFRRHD--LRK--------------LSPR 88
Cdd:cd03267   34 VEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLqPTSGEVrVAGLVPWKRRKkfLRRigvvfgqktqlwwdLPVI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLrgseLAMIFQepmtsLNPAftlgdqlseavmRHQTlsRAEAMTVALQILEKVQIPAaemrlkvypHQLSGGMRQR 168
Cdd:cd03267  114 DSFYL----LAAIYD-----LPPA------------RFKK--RLDELSELLDLEELLDTPV---------RQLSLGQRMR 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03267  162 AEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

13-252

3.34e-22

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 92.99 E-value: 3.34e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03218    1 LRAENLSKRYGKRKV--VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPD----SGKILLDGQDITKLPMHKRAR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRGSELAmifQEPmtSLNPAFTLGDQLSeAVMRHQTLSRAEAMTVALQILEKVQIpaAEMRlKVYPHQLSGGMRQRVMIA 172
Cdd:cd03218   75 LGIGYLP---QEA--SIFRKLTVEENIL-AVLEIRGLSKKEREEKLEELLEEFHI--THLR-KSKASSLSGGERRRVEIA 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:cd03218  146 RALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDR-GIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANE 224

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

11-252

3.91e-22

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 96.06 E-value: 3.91e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivsGEMHFRRHDLRKLSPREY 90
Cdd:PRK09536   2 PMIDVSDLSVEFGD--TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTA----GTVLVAGDDVEALSARAA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anlrGSELAMIFQEpmTSLNPAFTlGDQLSEaVMRHQTLSRAEAMT-----VALQILEKVQIPAAEMRLKVyphQLSGGM 165
Cdd:PRK09536  76 ----SRRVASVPQD--TSLSFEFD-VRQVVE-MGRTPHRSRFDTWTetdraAVERAMERTGVAQFADRPVT---SLSGGE 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMItHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:PRK09536 145 RQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAI-HDLDLAARYCDELVLLADGRVRAAGPP 223


                 ....*..
gi 550714244 246 EAIFADP 252
Cdd:PRK09536 224 ADVLTAD 230

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

13-243

5.10e-22

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 92.26 E-value: 5.10e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSpvSVLEDISLAVRAGeTLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKlSPREYAn 92
Cdd:cd03264    1 LQLENLTKRYGKK--RALDGVSLTLGPG-MYGLLGPNGAGKT----TLMRILATLTPPSSGTIRIDGQDVLK-QPQKLR- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgSELAMIFQEPMTSlnPAFTLGDQLSE-AVMRHQTLSRAEAMtvALQILEKVQIpaaEMRLKVYPHQLSGGMRQRVMI 171
Cdd:cd03264   72 ---RRIGYLPQEFGVY--PNFTVREFLDYiAWLKGIPSKEVKAR--VDEVLELVNL---GDRAKKKIGSLSGGMRRRVGI 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 172 AMALINHPKLLIADEPTTALDVtiqAQILALLNTLKE-ETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03264  142 AQALVGDPSILIVDEPTAGLDP---EERIRFRNLLSElGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211

PRK10908

cell division ATP-binding protein FtsE;

30-240

6.91e-22

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 92.25 E-value: 6.91e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREYANLRgSELAMIFQEPMTSL 109
Cdd:PRK10908  18 LQGVTFHMRPGEMAFLTGHSGAGKS----TLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLR-RQIGMIFQDHHLLM 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 110 ------NPAFTL--GDQLSEAVMRhqtlsRAEAMTVALQILEKVqipaaemrlKVYPHQLSGGMRQRVMIAMALINHPKL 181
Cdd:PRK10908  93 drtvydNVAIPLiiAGASGDDIRR-----RVSAALDKVGLLDKA---------KNFPIQLSGGEQQRVGIARAVVNKPAV 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 182 LIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:PRK10908 159 LLADEPTGNLDDALSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

12-252

6.95e-22

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 94.15 E-value: 6.95e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKF---AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPAS------ARIVSGEMHFRRHDL 82
Cdd:PRK13631  21 ILRVKNLYCVFdekQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKygtiqvGDIYIGDKKNNHELI 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  83 RKLSPREYAN---LRgSELAMIFQEPMTSLnpaftLGDQLSEAVMRHQT---LSRAEAMTVALQILEKVQIpaAEMRLKV 156
Cdd:PRK13631 101 TNPYSKKIKNfkeLR-RRVSMVFQFPEYQL-----FKDTIEKDIMFGPValgVKKSEAKKLAKFYLNKMGL--DDSYLER 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 157 YPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTaVLMITHDLGVVAEVAQQVAVMYA 236
Cdd:PRK13631 173 SPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKT-VFVITHTMEHVLEVADEVIVMDK 251

                        250
                 ....*....|....*.
gi 550714244 237 GQVVEQGSVEAIFADP 252
Cdd:PRK13631 252 GKILKTGTPYEIFTDQ 267

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

13-243

7.31e-22

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 90.84 E-value: 7.31e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHFRRHDlrklsPREYA 91
Cdd:cd03247    1 LSINNVSFSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKS-TLLQLLtGDLKPQ----QGEITLDGVP-----VSDLE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGSELAMIFQEPMTSlnpAFTLGDQLSEavmrhqtlsraeamtvalqilekvqipaaemrlkvyphQLSGGMRQRVMI 171
Cdd:cd03247   71 KALSSLISVLNQRPYLF---DTTLRNNLGR--------------------------------------RFSGGERQRLAL 109

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 172 AMALINHPKLLIADEPTTALDVTIQAQILALL-NTLKEETgtaVLMITHDLGVVaEVAQQVAVMYAGQVVEQG 243
Cdd:cd03247  110 ARILLQDAPIVLLDEPTVGLDPITERQLLSLIfEVLKDKT---LIWITHHLTGI-EHMDKILFLENGKIIMQG 178

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

13-246

8.27e-22

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 91.43 E-value: 8.27e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLlpASARIVSGEMHFRRHDLRKLSPREYAN 92
Cdd:cd03217    1 LEIKDLHVSVGGKEI--LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGH--PKYEVTEGEILFKGEDITDLPPEERAR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LrGseLAMIFQEPMTSlnPAFTLGDQLSEavmrhqtlsraeamtvalqILEKvqipaaemrlkvyphqLSGGMRQRVMIA 172
Cdd:cd03217   77 L-G--IFLAFQYPPEI--PGVKNADFLRY-------------------VNEG----------------FSGGEKKRNEIL 116

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHdLGVVAE--VAQQVAVMYAGQVVEQGSVE 246
Cdd:cd03217  117 QLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITH-YQRLLDyiKPDRVHVLYDGRIVKSGDKE 190

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

1-239

9.55e-22

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 92.43 E-value: 9.55e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   1 MTTIPFKDSTPVLrLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARIVSGE--MH 76
Cdd:PRK11247   2 MNTARLNQGTPLL-LNAVSKRYGER--TVLNQLDLHIPAGQFVAVVGRSGCGKS-TLLRLLAGLetPSAGELLAGTapLA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  77 FRRHDLRklspreyanlrgselaMIFQEpmTSLNPAFTLGDQLSEAVmrhqtlsRAEAMTVALQILEKVQIpaaEMRLKV 156
Cdd:PRK11247  78 EAREDTR----------------LMFQD--ARLLPWKKVIDNVGLGL-------KGQWRDAALQALAAVGL---ADRANE 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 157 YPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYA 236
Cdd:PRK11247 130 WPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEE 209


                 ...
gi 550714244 237 GQV 239
Cdd:PRK11247 210 GKI 212

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

15-250

9.85e-22

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 92.16 E-value: 9.85e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKS-ITSLALMGLLPASARI-VSGemhfrrHDLRKLSPreyAN 92
Cdd:cd03252    3 FEHVRFRYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKStLTKLIQRFYVPENGRVlVDG------HDLALADP---AW 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEPMT---SLNPAFTLGDqlsEAVMRHQTL---SRAEAMTVALQILEKVQIPAAEMRLKvyphqLSGGMR 166
Cdd:cd03252   74 LR-RQVGVVLQENVLfnrSIRDNIALAD---PGMSMERVIeaaKLAGAHDFISELPEGYDTIVGEQGAG-----LSGGQR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILAllNTLKEETGTAVLMITHDLGVVaEVAQQVAVMYAGQVVEQGSVE 246
Cdd:cd03252  145 QRIAIARALIHNPRILIFDEATSALDYESEHAIMR--NMHDICAGRTVIIIAHRLSTV-KNADRIIVMEKGRIVEQGSHD 221


                 ....
gi 550714244 247 AIFA 250
Cdd:cd03252  222 ELLA 225

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

27-250

1.21e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 93.61 E-value: 1.21e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLL-PASARI-VSGEMHFRRhdlRKlspreyANLRgsELAMIF- 102
Cdd:COG4586   35 VEAVDDISFTIEPGEIVGFIGPNGAGKS-TTIKMLtGILvPTSGEVrVLGYVPFKR---RK------EFAR--RIGVVFg 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 103 QE--------PMTSLNpafTLGD--QLSEAVMRHqtlsRAEAMTVALQILEKVQIPAaemrlkvypHQLSGGMRQRVMIA 172
Cdd:COG4586  103 QRsqlwwdlpAIDSFR---LLKAiyRIPDAEYKK----RLDELVELLDLGELLDTPV---------RQLSLGQRMRCELA 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:COG4586  167 AALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEELKE 244

cbiO

PRK13641

energy-coupling factor transporter ATPase;

19-253

1.25e-21

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 92.97 E-value: 1.25e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFAGSPVSVLE-----DISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARI-VSGEmhfrrHDLRKLSPREYA 91
Cdd:PRK13641   7 NVDYIYSPGTPMEkkgldNISFELEEGSFVALVGHTGSGKSTLMQHFNALLkPSSGTItIAGY-----HITPETGNKNLK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRgSELAMIFQEPMTSLNPAFTLGDqlseaVM---RHQTLSRAEAMTVALQILEKVQIPaaEMRLKVYPHQLSGGMRQR 168
Cdd:PRK13641  82 KLR-KKVSLVFQFPEAQLFENTVLKD-----VEfgpKNFGFSEDEAKEKALKWLKKVGLS--EDLISKSPFELSGGQMRR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:PRK13641 154 VAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEI 232


                 ....*
gi 550714244 249 FADPQ 253
Cdd:PRK13641 233 FSDKE 237

cbiO

PRK13646

energy-coupling factor transporter ATPase;

30-251

1.55e-21

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 92.54 E-value: 1.55e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFrrhdLRKLSPREYANLRgSELAMIFQEPMTS 108
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLkPTTGTVTVDDITI----THKTKDKYIRPVR-KRIGMVFQFPESQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 LnpaftLGDQLSEAVM---RHQTLSRAEAMTVALQILEKVQIPAAEMRLKvyPHQLSGGMRQRVMIAMALINHPKLLIAD 185
Cdd:PRK13646  98 L-----FEDTVEREIIfgpKNFKMNLDEVKNYAHRLLMDLGFSRDVMSQS--PFQMSGGQMRKIAIVSILAMNPDIIVLD 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 186 EPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PRK13646 171 EPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD 236

PRK13549

xylose transporter ATP-binding subunit; Provisional

9-238

2.21e-21

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 94.61 E-value: 2.21e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAriVSGEMHFRRHDLRklspr 88
Cdd:PRK13549   2 MEYLLEMKNITKTFGG--VKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGT--YEGEIIFEGEELQ----- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 eYANLRGSE---LAMIFQEPMtsLNPAFTLGDQ--LSEAVMRHQTLSRAEAMTVALQILEKVQI---PAaemrLKVYphQ 160
Cdd:PRK13549  73 -ASNIRDTEragIAIIHQELA--LVKELSVLENifLGNEITPGGIMDYDAMYLRAQKLLAQLKLdinPA----TPVG--N 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:PRK13549 144 LGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220

GguA

NF040905

sugar ABC transporter ATP-binding protein;

12-241

2.40e-21

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 94.47 E-value: 2.40e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAriVSGEMHFRRhdlrklSPREYA 91
Cdd:NF040905   1 ILEMRGITKTFPG--VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGS--YEGEILFDG------EVCRFK 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGSE---LAMIFQE----PMTSLNPAFTLGDQLSE--AVMRHQTLSRAEAMtvalqiLEKVqipaaemRLKVYPHQLS 162
Cdd:NF040905  71 DIRDSEalgIVIIHQElaliPYLSIAENIFLGNERAKrgVIDWNETNRRAREL------LAKV-------GLDESPDTLV 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 G----GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:NF040905 138 TdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216


                 ...
gi 550714244 239 VVE 241
Cdd:NF040905 217 TIE 219

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

12-252

2.59e-21

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 91.79 E-value: 2.59e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSpVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYA 91
Cdd:PRK13652   3 LIETRDLCYSYSGS-KEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPT----SGSVLIRGEPITKENIREVR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGselaMIFQEPmtslnpaftlGDQLSEAVMRHQ------TLSRAEAmTVALQILEKVQIPAAEMRLKVYPHQLSGGM 165
Cdd:PRK13652  78 KFVG----LVFQNP----------DDQIFSPTVEQDiafgpiNLGLDEE-TVAHRVSSALHMLGLEELRDRVPHHLSGGE 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSV 245
Cdd:PRK13652 143 KKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTV 222


                 ....*..
gi 550714244 246 EAIFADP 252
Cdd:PRK13652 223 EEIFLQP 229

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

19-244

2.76e-21

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 90.75 E-value: 2.76e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFA-GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSpreYANLRgSE 97
Cdd:cd03254    7 NVNFSyDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQ----KGQILIDGIDIRDIS---RKSLR-SM 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  98 LAMIFQEPMTslnpaftlgdqLSEAVMRHQTLSRAEA-MTVALQILEKVQIPAAEMRL-KVYPHQ-------LSGGMRQR 168
Cdd:cd03254   79 IGVVLQDTFL-----------FSGTIMENIRLGRPNAtDEEVIEAAKEAGAHDFIMKLpNGYDTVlgenggnLSQGERQL 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDV----TIQAQILALLNtlkeetGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGS 244
Cdd:cd03254  148 LAIARAMLRDPKILILDEATSNIDTetekLIQEALEKLMK------GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGT 220

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

13-240

4.17e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 90.92 E-value: 4.17e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKF-AGSP--VSVLEDISLAVRAGETLALVGESGCGKSiTslaLMGLLPASARIVSGEMHFRRHDLRKLSprE 89
Cdd:COG1101    2 LELKNLSKTFnPGTVneKRALDGLNLTIEEGDFVTVIGSNGAGKS-T---LLNAIAGSLPPDSGSILIDGKDVTKLP--E 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YAnlRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQ--TLSRA------EAMTVALQI----LEKvqipaaemRLKVY 157
Cdd:COG1101   76 YK--RAKYIGRVFQDPMMGTAPSMTIEENLALAYRRGKrrGLRRGltkkrrELFRELLATlglgLEN--------RLDTK 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:COG1101  146 VGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEG 225


                 ...
gi 550714244 238 QVV 240
Cdd:COG1101  226 RII 228

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

15-237

5.27e-21

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 93.59 E-value: 5.27e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTslalmgLLpasaRIVSGEMH------FRRHDLR----- 83
Cdd:COG0488    1 LENLSKSFGGRPL--LDDVSLSINPGDRIGLVGRNGAGKS-T------LL----KILAGELEpdsgevSIPKGLRigylp 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  84 -------KLSPREY---ANLRGSELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTL------SRAEamtvalQILEKVQI 147
Cdd:COG0488   68 qepplddDLTVLDTvldGDAELRALEAELEELEAKLAEPDEDLERLAELQEEFEALggweaeARAE------EILSGLGF 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 148 PAAEMRLKVypHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDvtIQAqILALLNTLKEETGTaVLMITHD---L--- 221
Cdd:COG0488  142 PEEDLDRPV--SELSGGWRRRVALARALLSEPDLLLLDEPTNHLD--LES-IEWLEEFLKNYPGT-VLVVSHDryfLdrv 215

                        250
                 ....*....|....*..
gi 550714244 222 -GVVAEVAQQVAVMYAG 237
Cdd:COG0488  216 aTRILELDRGKLTLYPG 232

PRK03695

vitamin B12-transporter ATPase; Provisional

13-244

7.95e-21

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 89.61 E-value: 7.95e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKfagspvSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPAsarivSGEMHFRRHDLRKLSPREYA 91
Cdd:PRK03695   1 MQLNDVAVS------TRLGPLSAEVRAGEILHLVGPNGAGKS-TLLARMaGLLPG-----SGSIQFAGQPLEAWSAAELA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGSeLAMifQEPMTSLNPAF-----TLGDQLSEAVMRHqTLSRaeaMTVALQILEKVQIPAaemrlkvypHQLSGGMR 166
Cdd:PRK03695  69 RHRAY-LSQ--QQTPPFAMPVFqyltlHQPDKTRTEAVAS-ALNE---VAEALGLDDKLGRSV---------NQLSGGEW 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMAL------IN-HPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:PRK03695 133 QRVRLAAVVlqvwpdINpAGQLLLLDEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKL 211


                 ....*
gi 550714244 240 VEQGS 244
Cdd:PRK03695 212 LASGR 216

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

8-233

8.15e-21

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 93.12 E-value: 8.15e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    8 DSTPVLRLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEmhfrrhdlRKLS 86
Cdd:TIGR02857 317 APASSLEFSGVSVAYPGRRP-ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVdPTEGSIAVNG--------VPLA 387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   87 PREYANLRGSeLAMIFQEPM---TSL--NPAFTLGDQlSEAVMRhQTLSRAEAMTVALQILEKVQIPAAEmrlkvYPHQL 161
Cdd:TIGR02857 388 DADADSWRDQ-IAWVPQHPFlfaGTIaeNIRLARPDA-SDAEIR-EALERAGLDEFVAALPQGLDTPIGE-----GGAGL 459

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244  162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEVAQQVAV 233
Cdd:TIGR02857 460 SGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALADRIVVL 529

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

30-253

1.27e-20

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 89.79 E-value: 1.27e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGL-LPASARI-VSGemhfrrhdlRKLSPREYANLRgSELAMIFQEPmt 107
Cdd:PRK13647  21 LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIyLPQRGRVkVMG---------REVNAENEKWVR-SKVGLVFQDP-- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 slnpaftlGDQLSEAVM--------RHQTLSRAEamtvalqILEKVQIPAAEMRLKVY----PHQLSGGMRQRVMIAMAL 175
Cdd:PRK13647  89 --------DDQVFSSTVwddvafgpVNMGLDKDE-------VERRVEEALKAVRMWDFrdkpPYHLSYGQKKRVAIAGVL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 176 INHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEaIFADPQ 253
Cdd:PRK13647 154 AMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS-LLTDED 229

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

10-224

1.30e-20

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 89.40 E-value: 1.30e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSgemhfRRHDLRklspre 89
Cdd:PRK09544   2 TSLVSLENVSVSFGQR--RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK-----RNGKLR------ 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanlrgseLAMIFQEpmTSLNPAFTLgdqlseAVMRHQTLSRAEAMTVALQILEKVQipaAEMRLKVYPHQLSGGMRQRV 169
Cdd:PRK09544  69 --------IGYVPQK--LYLDTTLPL------TVNRFLRLRPGTKKEDILPALKRVQ---AGHLIDAPMQKLSGGETQRV 129

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 170 MIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVV 224
Cdd:PRK09544 130 LLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLV 184

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

13-243

1.41e-20

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 88.58 E-value: 1.41e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKF--AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARI--VSGemhFRRHDlrklSPR 88
Cdd:cd03266    2 ITADALTKRFrdVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFatVDG---FDVVK----EPA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EyANLRgselaMIFQEPMTSLNPAFTLGDQLS-----EAVMRHQTLSRAEAMTVALQILEKVQIPAAEMrlkvyphqlSG 163
Cdd:cd03266   75 E-ARRR-----LGFVSDSTGLYDRLTARENLEyfaglYGLKGDELTARLEELADRLGMEELLDRRVGGF---------ST 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03266  140 GMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

34-243

1.62e-20

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 87.99 E-value: 1.62e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   34 SLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREyanlrgSELAMIFQEpmTSLNPAF 113
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKS----TLLNLIAGFIEPASGSIKVNDQSHTGLAPYQ------RPVSMLFQE--NNLFAHL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  114 TLGDQLSEAVMRHQTLSRAEAmtvalqilEKVQIPAAEMRLKVY----PHQLSGGMRQRVMIAMALINHPKLLIADEPTT 189
Cdd:TIGR01277  86 TVRQNIGLGLHPGLKLNAEQQ--------EKVVDAAQQVGIADYldrlPEQLSGGQRQRVALARCLVRPNPILLLDEPFS 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 550714244  190 ALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:TIGR01277 158 ALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211

cbiO

PRK13644

energy-coupling factor transporter ATPase;

12-267

1.70e-20

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 89.66 E-value: 1.70e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA-GSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVsgemhfrrhdLRKLSPRE 89
Cdd:PRK13644   1 MIRLENVSYSYPdGTPA--LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLrPQKGKVL----------VSGIDTGD 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLRGSE--LAMIFQEPMTSLnpaftLGDQLSEAVmrhqTLSRAEAMTVALQILEKVQIPAAEMRLKVY----PHQLSG 163
Cdd:PRK13644  69 FSKLQGIRklVGIVFQNPETQF-----VGRTVEEDL----AFGPENLCLPPIEIRKRVDRALAEIGLEKYrhrsPKTLSG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVaEVAQQVAVMYAGQVVEQG 243
Cdd:PRK13644 140 GQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEEL-HDADRIIVMDRGKIVLEG 217

                        250       260
                 ....*....|....*....|....
gi 550714244 244 SVEAIFADPQHPYtIGLmgSIPSL 267
Cdd:PRK13644 218 EPENVLSDVSLQT-LGL--TPPSL 238

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

13-219

3.89e-20

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 91.02 E-value: 3.89e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFA-GSPVsvLEDISLAVRAGETLALVGESGCGKSitSL--ALMGLLPASarivSGEMHFrrhdlrklsPRe 89
Cdd:COG4178  363 LALEDLTLRTPdGRPL--LEDLSLSLKPGERLLITGPSGSGKS--TLlrAIAGLWPYG----SGRIAR---------PA- 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanlrGSELAMIFQEPMTslnPAFTLGDQLS--EAvmrHQTLSRAEAmtvaLQILEKVQIPAAEMRLKV---YPHQLSGG 164
Cdd:COG4178  425 -----GARVLFLPQRPYL---PLGTLREALLypAT---AEAFSDAEL----REALEAVGLGHLAERLDEeadWDQVLSLG 489

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLntLKEETGTAVLMITH 219
Cdd:COG4178  490 EQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLL--REELPGTTVISVGH 542

PRK13633

energy-coupling factor transporter ATPase;

29-260

5.32e-20

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 88.22 E-value: 5.32e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSprEYANLRgSELAMIFQEPmts 108
Cdd:PRK13633  25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPS----EGKVYVDGLDTSDEE--NLWDIR-NKAGMVFQNP--- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 lnpaftlGDQLSEAVMRHQtlsraeamtVALQIlEKVQIPAAEMRLKV-----------Y----PHQLSGGMRQRVMIAM 173
Cdd:PRK13633  95 -------DNQIVATIVEED---------VAFGP-ENLGIPPEEIRERVdeslkkvgmyeYrrhaPHLLSGGQKQRVAIAG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 174 ALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSVEAIFADPQ 253
Cdd:PRK13633 158 ILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKEVE 236


                 ....*..
gi 550714244 254 HPYTIGL 260
Cdd:PRK13633 237 MMKKIGL 243

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

10-251

1.08e-19

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 89.84 E-value: 1.08e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFagSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPRE 89
Cdd:PRK09700   3 TPYISMAGIGKSF--GPVHALKSVNLTVYPGEIHALLGENGAGKS----TLMKVLSGIHEPTKGTITINNINYNKLDHKL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLrgsELAMIFQEpmtslnpaFTLGDQLSEA----VMRHQTlsrAEAMTVALQILEKVQIPAAEMRLKVYPH------ 159
Cdd:PRK09700  77 AAQL---GIGIIYQE--------LSVIDELTVLenlyIGRHLT---KKVCGVNIIDWREMRVRAAMMLLRVGLKvdldek 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 --QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:PRK09700 143 vaNLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDG 221

                        250
                 ....*....|....
gi 550714244 238 QVVEQGSVEAIFAD 251
Cdd:PRK09700 222 SSVCSGMVSDVSND 235

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

13-242

1.90e-19

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 87.59 E-value: 1.90e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLnVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitSLALM--GLlpasARIVSGEMHFRRHDLRKLSPREy 90
Cdd:PRK11650   4 LKLQAV-RKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKS--TLLRMvaGL----ERITSGEIWIGGRVVNELEPAD- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anlRGseLAMIFQEpmTSLNPAFTLGDQLSEAvMRHQTLSRAEamtVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRVM 170
Cdd:PRK11650  76 ---RD--IAMVFQN--YALYPHMSVRENMAYG-LKIRGMPKAE---IEERVAEAARILELEPLLDRKPRELSGGQRQRVA 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGqVVEQ 242
Cdd:PRK11650 145 MGRAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGG-VAEQ 215

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

13-250

1.98e-19

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 89.04 E-value: 1.98e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitSLA--LMGLLPASarivSGEMHFRRHDLRKLSPREY 90
Cdd:COG4618  331 LSVENLTVVPPGSKRPILRGVSFSLEPGEVLGVIGPSGSGKS--TLArlLVGVWPPT----AGSVRLDGADLSQWDREEL 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRG-----SEL--AMIFQepmtslNPAfTLGDQLSEAVMRHQTLSRAEAMtvalqILekvQIPAA-EMRLKVYPHQLS 162
Cdd:COG4618  405 GRHIGylpqdVELfdGTIAE------NIA-RFGDADPEKVVAAAKLAGVHEM-----IL---RLPDGyDTRIGEGGARLS 469

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 GGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAeVAQQVAVMYAGQVVEQ 242
Cdd:COG4618  470 GGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPSLLA-AVDKLLVLRDGRVQAF 547


                 ....*...
gi 550714244 243 GSVEAIFA 250
Cdd:COG4618  548 GPRDEVLA 555

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

13-250

2.53e-19

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 88.71 E-value: 2.53e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   13 LRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGL---LPASARIV------------------ 71
Cdd:TIGR03269   1 IEVKNLTKKFDG--KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqyEPTSGRIIyhvalcekcgyverpskv 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   72 -------SGEMHFRRHDLRKLSPREYANLRgSELAMIFQEpmtslnpAFTL-GDQ-LSEAVMR--HQT-LSRAEAMTVAL 139
Cdd:TIGR03269  79 gepcpvcGGTLEPEEVDFWNLSDKLRRRIR-KRIAIMLQR-------TFALyGDDtVLDNVLEalEEIgYEGKEAVGRAV 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  140 QILEKVQIpaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITH 219
Cdd:TIGR03269 151 DLIEMVQL---SHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSH 227

                         250       260       270
                  ....*....|....*....|....*....|.
gi 550714244  220 DLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:TIGR03269 228 WPEVIEDLSDKAIWLENGEIKEEGTPDEVVA 258

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

22-226

3.11e-19

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 84.21 E-value: 3.11e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  22 FAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVsgemhfRRHdlrklspreyanlRGSELAMI 101
Cdd:NF040873   2 YGGRPV--LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV------RRA-------------GGARVAYV 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 102 FQEpmTSLNPAF--TLGDQLSEAVMRHQTLSR---AEAMTVALQILEKVQIPA-AEMRLkvypHQLSGGMRQRVMIAMAL 175
Cdd:NF040873  61 PQR--SEVPDSLplTVRDLVAMGRWARRGLWRrltRDDRAAVDDALERVGLADlAGRQL----GELSGGQRQRALLAQGL 134

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 550714244 176 INHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAE 226
Cdd:NF040873 135 AQEADLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRR 184

cbiO

PRK13645

energy-coupling factor transporter ATPase;

30-251

3.26e-19

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 86.22 E-value: 3.26e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFRRhDLRKLspREYANLRgSELAMIFQEPMTS 108
Cdd:PRK13645  27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIiSETGQTIVGDYAIPA-NLKKI--KEVKRLR-KEIGLVFQFPEYQ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 LNPAFTLGDQLSEAVmrHQTLSRAEAMTVALQILEKVQIPaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPT 188
Cdd:PRK13645 103 LFQETIEKDIAFGPV--NLGENKQEAYKKVPELLKLVQLP--EDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPT 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 189 TALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PRK13645 179 GGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN 241

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

29-250

5.44e-19

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 85.06 E-value: 5.44e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLrKLSPREYANLRgSELAMIFQEPMTS 108
Cdd:PRK13638  16 VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLL----RPQKGAVLWQGKPL-DYSKRGLLALR-QQVATVFQDPEQQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 LnpAFTlgDQLSEAVMRHQTLSRAEAmTVALQILEKVQIPAAEmRLKVYPHQ-LSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:PRK13638  90 I--FYT--DIDSDIAFSLRNLGVPEA-EITRRVDEALTLVDAQ-HFRHQPIQcLSHGQKKRVAIAGALVLQARYLLLDEP 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 188 TTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:PRK13638 164 TAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFA 225

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

10-251

7.50e-19

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 87.03 E-value: 7.50e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVK-FAgspvsvleDISLAVRAGETLALVGESGCGKsiTSLA--LMGLLPASarivSGEMHFRRHDLRKLS 86
Cdd:PRK15439 266 APVLTVEDLTGEgFR--------NISLEVRAGEILGLAGVVGAGR--TELAetLYGLRPAR----GGRIMLNGKEINALS 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PREyANLRG-------SELAMIFQEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQI-LEKVQIPAaemrlkvyp 158
Cdd:PRK15439 332 TAQ-RLARGlvylpedRQSSGLYLDAPLAWNVCALTHNRRGFWIKPARENAVLERYRRALNIkFNHAEQAA--------- 401

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:PRK15439 402 RTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGE 480

                        250
                 ....*....|...
gi 550714244 239 VVEQGSVEAIFAD 251
Cdd:PRK15439 481 ISGALTGAAINVD 493

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

11-257

8.33e-19

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 84.70 E-value: 8.33e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNvkFAGSPVSVLEDISLAVRAGETLALVGESGCGKS--ITSLALMGLLPASARiVSGEMHF-------RRHD 81
Cdd:PRK14258   6 PAIKVNNLS--FYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKStfLKCLNRMNELESEVR-VEGRVEFfnqniyeRRVN 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  82 LRKLSpreyanlrgSELAMIFQEPmtSLNPaFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIpAAEMRLKVYPH-- 159
Cdd:PRK14258  83 LNRLR---------RQVSMVHPKP--NLFP-MSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADL-WDEIKHKIHKSal 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYA--- 236
Cdd:PRK14258 150 DLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnen 229

                        250       260
                 ....*....|....*....|...
gi 550714244 237 --GQVVEQGSVEAIFADPQHPYT 257
Cdd:PRK14258 230 riGQLVEFGLTKKIFNSPHDSRT 252

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

19-250

9.06e-19

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 87.00 E-value: 9.06e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFA--GSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRklsprEY--ANLR 94
Cdd:PRK11176 346 NVTFTypGKEVPALRNINFKIPAGKTVALVGRSGSGKS----TIANLLTRFYDIDEGEILLDGHDLR-----DYtlASLR 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 gSELAMIFQE-----PMTSLNPAFTLGDQLSeavmRHQtLSRAEAMTVALQILEKVqipaaemrlkvyPH---------- 159
Cdd:PRK11176 417 -NQVALVSQNvhlfnDTIANNIAYARTEQYS----REQ-IEEAARMAYAMDFINKM------------DNgldtvigeng 478

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 -QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTL-KEETgtaVLMITHDLGVVaEVAQQVAVMYAG 237
Cdd:PRK11176 479 vLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELqKNRT---SLVIAHRLSTI-EKADEILVVEDG 554

                        250
                 ....*....|...
gi 550714244 238 QVVEQGSVEAIFA 250
Cdd:PRK11176 555 EIVERGTHAELLA 567

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

27-252

9.29e-19

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 87.08 E-value: 9.29e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   27 VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARI-VSGEmhfrrhDLRKLsprEYANLRgSELAMIFQE 104
Cdd:TIGR00958 494 VPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYqPTGGQVlLDGV------PLVQY---DHHYLH-RQVALVGQE 563

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  105 PM-----TSLNPAFTLGDQLSEAVMrhqtlSRAEAMTVALQILEKVQIPAAEMRLKvyPHQLSGGMRQRVMIAMALINHP 179
Cdd:TIGR00958 564 PVlfsgsVRENIAYGLTDTPDEEIM-----AAAKAANAHDFIMEFPNGYDTEVGEK--GSQLSGGQKQRIAIARALVRKP 636

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244  180 KLLIADEPTTALDvtiqAQILALLNTLKEETGTAVLMITHDLGVVaEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:TIGR00958 637 RVLILDEATSALD----AECEQLLQESRSRASRTVLLIAHRLSTV-ERADQILVLKKGSVVEMGTHKQLMEDQ 704

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

19-250

1.02e-18

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 87.08 E-value: 1.02e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFA-GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMhfrRHDLRKLSPREYANLRGSe 97
Cdd:PRK10790 345 NVSFAyRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLT----EGEI---RLDGRPLSSLSHSVLRQG- 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  98 LAMIFQEPMTSLNPAF---TLGDQLSEAVMrhqtlsraeamtvaLQILEKVQIpaAEM----------RLKVYPHQLSGG 164
Cdd:PRK10790 417 VAMVQQDPVVLADTFLanvTLGRDISEEQV--------------WQALETVQL--AELarslpdglytPLGEQGNNLSVG 480

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGS 244
Cdd:PRK10790 481 QKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH--TTLVVIAHRLSTIVE-ADTILVLHRGQAVEQGT 557


                 ....*.
gi 550714244 245 VEAIFA 250
Cdd:PRK10790 558 HQQLLA 563

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

7-244

1.03e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 86.80 E-value: 1.03e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   7 KDSTPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLS 86
Cdd:PRK11160 333 AADQVSLTLNNVSFTYPDQPQPVLKGLSLQIKAGEKVALLGRTGCGKS----TLLQLLTRAWDPQQGEILLNGQPIADYS 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PreyANLRGSelamifqepMTSLNP-----AFTLGDQLSEAvmrhQTLSRAEAMTVALQI--LEKV--QIPAAEMRLKVY 157
Cdd:PRK11160 409 E---AALRQA---------ISVVSQrvhlfSATLRDNLLLA----APNASDEALIEVLQQvgLEKLleDDKGLNAWLGEG 472

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLntLKEETGTAVLMITHDLGVVAEVaQQVAVMYAG 237
Cdd:PRK11160 473 GRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELL--AEHAQNKTVLMITHRLTGLEQF-DRICVMDNG 549


                 ....*..
gi 550714244 238 QVVEQGS 244
Cdd:PRK11160 550 QIIEQGT 556

cbiO

PRK13649

energy-coupling factor transporter ATPase;

15-271

1.03e-18

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 84.41 E-value: 1.03e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKF-AGSPVS--VLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFRRHDLRKlsprEY 90
Cdd:PRK13649   5 LQNVSYTYqAGTPFEgrALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHvPTQGSVRVDDTLITSTSKNK----DI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRgSELAMIFQEPMTSLnpaftlgdqLSEAVMRHQT-------LSRAEAMTVALQILEKVQIpaAEMRLKVYPHQLSG 163
Cdd:PRK13649  81 KQIR-KKVGLVFQFPESQL---------FEETVLKDVAfgpqnfgVSQEEAEALAREKLALVGI--SESLFEKNPFELSG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLkEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:PRK13649 149 GQMRRVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKL-HQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSG 227

                        250       260
                 ....*....|....*....|....*...
gi 550714244 244 SVEAIFADpqhpytIGLMGSIpSLGVRK 271
Cdd:PRK13649 228 KPKDIFQD------VDFLEEK-QLGVPK 248

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

33-252

1.39e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 86.44 E-value: 1.39e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  33 ISLAVRAGETLALVGESGCGKsiTSL--ALMGLLPasariVSGEMHFRRHDLRKLSPREYAnlrgSELAMIFQEPM---T 107
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGK--TSLlnALLGFLP-----YQGSLKINGIELRELDPESWR----KHLSWVGQNPQlphG 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 SLNPAFTLGD-QLSEAVMrHQTLSRAEAMTVALQILEKVQIPAAEMRLKvyphqLSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:PRK11174 438 TLRDNVLLGNpDASDEQL-QQALENAWVSEFLPLLPQGLDTPIGDQAAG-----LSVGQAQRLALARALLQPCQLLLLDE 511

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 187 PTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEVaQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:PRK11174 512 PTASLDAHSEQLVMQALNAASR--RQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQGDYAELSQAG 574

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

13-244

1.97e-18

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 82.07 E-value: 1.97e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREyan 92
Cdd:cd03369    7 IEVENLSVRYAPDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAE----EGKIEIDGIDISTIPLED--- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEPM-------TSLNPAftlgDQLSEavmrhqtlsraeamtvalqilekVQIPAAeMRLKVYPHQLSGGM 165
Cdd:cd03369   80 LR-SSLTIIPQDPTlfsgtirSNLDPF----DEYSD-----------------------EEIYGA-LRVSEGGLNLSQGQ 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQIlalLNTLKEE-TGTAVLMITHDLGVVAEVAqQVAVMYAGQVVEQGS 244
Cdd:cd03369  131 RQLLCLARALLKRPRVLVLDEATASIDYATDALI---QKTIREEfTNSTILTIAHRLRTIIDYD-KILVMDAGEVKEYDH 206

cbiO

PRK13643

energy-coupling factor transporter ATPase;

12-251

2.78e-18

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 83.63 E-value: 2.78e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFA-GSPVS--VLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFRRHDLRKlsp 87
Cdd:PRK13643   1 MIKFEKVNYTYQpNSPFAsrALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLqPTEGKVTVGDIVVSSTSKQK--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 rEYANLRgSELAMIFQEPMTSLNPAFTLGDQLSEAvmRHQTLSRAEAMTVALQILEKVQIpAAEMRLKVyPHQLSGGMRQ 167
Cdd:PRK13643  78 -EIKPVR-KKVGVVFQFPESQLFEETVLKDVAFGP--QNFGIPKEKAEKIAAEKLEMVGL-ADEFWEKS-PFELSGGQMR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLkEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEA 247
Cdd:PRK13643 152 RVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESI-HQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSD 230


                 ....
gi 550714244 248 IFAD 251
Cdd:PRK13643 231 VFQE 234

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

14-248

6.09e-18

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 81.67 E-value: 6.09e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  14 RLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSLALMG-LLPASarivSGEMHFRRHDLRKLSPREYAN 92
Cdd:COG4604    3 EIKNVSKRYGGKVV--LDDVSLTIPKGGITALIGPNGAGKS-TLLSMISrLLPPD----SGEVLVDGLDVATTPSRELAK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgsELAMIFQEPmtSLNPAFTLgdqlSEAVM--R---HQ---TLSRAEAMTVALQILEkvqipAAEMRLKvYPHQLSGG 164
Cdd:COG4604   76 ----RLAILRQEN--HINSRLTV----RELVAfgRfpySKgrlTAEDREIIDEAIAYLD-----LEDLADR-YLDELSGG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:COG4604  140 QRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGT 219


                 ....
gi 550714244 245 VEAI 248
Cdd:COG4604  220 PEEI 223

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

12-253

6.13e-18

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 81.86 E-value: 6.13e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivsGEMHFRRHDLRKLSPREYA 91
Cdd:PRK10895   3 TLTAKNLAKAYKGR--RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDA----GNIIIDDEDISLLPLHARA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 nLRGseLAMIFQEPmtSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKvypHQLSGGMRQRVMI 171
Cdd:PRK10895  77 -RRG--IGYLPQEA--SIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMG---QSLSGGERRRVEI 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 172 AMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PRK10895 149 ARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLR-DSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQD 227


                 ..
gi 550714244 252 PQ 253
Cdd:PRK10895 228 EH 229

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

19-244

6.49e-18

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 84.49 E-value: 6.49e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFAGSPVS-VLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARI-VSGemhfrrHDLRKLSPreyANLRG 95
Cdd:COG5265  362 NVSFGYDPERpILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYdVTSGRIlIDG------QDIRDVTQ---ASLRA 432

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  96 SeLAMIFQEpmTSLnpaF--TLGDQLS----EAvmrhqtlSRAEAMTVA--LQIL-------EKVQIPAAEMRLKvyphq 160
Cdd:COG5265  433 A-IGIVPQD--TVL---FndTIAYNIAygrpDA-------SEEEVEAAAraAQIHdfieslpDGYDTRVGERGLK----- 494

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMYAGQVV 240
Cdd:COG5265  495 LSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVAR--GRTTLVIAHRLSTIVD-ADEILVLEAGRIV 571


                 ....
gi 550714244 241 EQGS 244
Cdd:COG5265  572 ERGT 575

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

12-259

6.52e-18

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 84.49 E-value: 6.52e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAriVSGEMHFRRhdlrklSPREYA 91
Cdd:TIGR02633   1 LLEMKGIVKTFGG--VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGT--WDGEIYWSG------SPLKAS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   92 NLRGSE---LAMIFQEPMtsLNPAFTLGDQL---SEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVypHQLSGGM 165
Cdd:TIGR02633  71 NIRDTEragIVIIHQELT--LVPELSVAENIflgNEITLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPV--GDYGGGQ 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  166 RQRVMIAMALINHPKLLIADEPTTALdvtIQAQILALLNTLKE--ETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:TIGR02633 147 QQLVEIAKALNKQARLLILDEPSSSL---TEKETEILLDIIRDlkAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATK 223

                         250       260       270
                  ....*....|....*....|....*....|.
gi 550714244  244 SVEAIFAD---------------PQHPYTIG 259
Cdd:TIGR02633 224 DMSTMSEDdiitmmvgreitslyPHEPHEIG 254

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

12-243

7.81e-18

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 80.29 E-value: 7.81e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVS----VLEDISLAVRAGETLALVGESGCGKsiTSL--ALMGLLpaSARIVSGEMHFRRHDLRKL 85
Cdd:cd03213    3 TLSFRNLTVTVKSSPSKsgkqLLKNVSGKAKPGELTAIMGPSGAGK--STLlnALAGRR--TGLGVSGEVLINGRPLDKR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPReyanlrgSELAMIFQEpmtslnpaftlgDQLseavmrHQTLSRAEAMTVAlqilekvqipaAEMRlkvyphQLSGGM 165
Cdd:cd03213   79 SFR-------KIIGYVPQD------------DIL------HPTLTVRETLMFA-----------AKLR------GLSGGE 116

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDL-GVVAEVAQQVAVMYAGQVVEQG 243
Cdd:cd03213  117 RKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLA-DTGRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

12-239

1.39e-17

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 80.21 E-value: 1.39e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSP-VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFrrhDLRKLSPREY 90
Cdd:cd03248   11 IVKFQNVTFAYPTRPdTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQ----GGQVLL---DGKPISQYEH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRgSELAMIFQEPMTSL-----NPAFTLGDQLSEAVMRHQTLSRAEAMtvalqILEKVQIPAAEMRLKvyPHQLSGGM 165
Cdd:cd03248   84 KYLH-SKVSLVGQEPVLFArslqdNIAYGLQSCSFECVKEAAQKAHAHSF-----ISELASGYDTEVGEK--GSQLSGGQ 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550714244 166 RQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVaEVAQQVAVMYAGQV 239
Cdd:cd03248  156 KQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPER--RTVLVIAHRLSTV-ERADQILVLDGGRI 226

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

11-253

1.61e-17

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 80.46 E-value: 1.61e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREY 90
Cdd:COG1137    2 MTLEAENLVKSYGKRTV--VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPD----SGRIFLDGEDITHLPMHKR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRGSELAmifQEPmtSLnpaF---TLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQIpaAEMRlKVYPHQLSGGMRQ 167
Cdd:COG1137   76 ARLGIGYLP---QEA--SI---FrklTVEDNI-LAVLELRKLSKKEREERLEELLEEFGI--THLR-KSKAYSLSGGERR 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALD-VTIqAQILALLNTLKEEtGTAVLmIT-HD----LGVVaevaQQVAVMYAGQVVE 241
Cdd:COG1137  144 RVEIARALATNPKFILLDEPFAGVDpIAV-ADIQKIIRHLKER-GIGVL-ITdHNvretLGIC----DRAYIISEGKVLA 216

                        250
                 ....*....|..
gi 550714244 242 QGSVEAIFADPQ 253
Cdd:COG1137  217 EGTPEEILNNPL 228

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

13-234

1.67e-17

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 77.87 E-value: 1.67e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTslalmgLLpasaRIVSGEMhfrrhdlrklspreyan 92
Cdd:cd03221    1 IELENLSKTYGGKLL--LKDISLTINPGDRIGLVGRNGAGKS-T------LL----KLIAGEL----------------- 50

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lrgselamifqEPmtslnpafTLGdqlseavmrhqTLSRAEAMTVAlqilekvqipaaemrlkvYPHQLSGGMRQRVMIA 172
Cdd:cd03221   51 -----------EP--------DEG-----------IVTWGSTVKIG------------------YFEQLSGGEKMRLALA 82

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244 173 MALINHPKLLIADEPTTALDVTiqaQILALLNTLKEETGTaVLMITHDLGVVAEVAQQVAVM 234
Cdd:cd03221   83 KLLLENPNLLLLDEPTNHLDLE---SIEALEEALKEYPGT-VILVSHDRYFLDQVATKIIEL 140

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

11-241

2.20e-17

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 82.81 E-value: 2.20e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSiTSL-ALMGLLPASarivSGEMHfrrhdlrklspre 89
Cdd:COG0488  314 KVLELEGLSKSYGDKTL--LDDLSLRIDRGDRIGLIGPNGAGKS-TLLkLLAGELEPD----SGTVK------------- 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanlRGSELAMIF--QEpMTSLNPAFTLGDQLSEAvmrHQTLSRAEAMtvalQILEKVQIPAAEMRLKVypHQLSGGMRQ 167
Cdd:COG0488  374 ----LGETVKIGYfdQH-QEELDPDKTVLDELRDG---APGGTEQEVR----GYLGRFLFSGDDAFKPV--GVLSGGEKA 439

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALDV-TIQaqilALLNTLKEETGTaVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:COG0488  440 RLALAKLLLSPPNVLLLDEPTNHLDIeTLE----ALEEALDDFPGT-VLLVSHDRYFLDRVATRILEFEDGGVRE 509

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

27-250

2.47e-17

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 80.13 E-value: 2.47e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMHfrrhdlrklspreyanLRGSELAMIfqEP 105
Cdd:COG1134   39 FWALKDVSFEVERGESVGIIGRNGAGKS-TLLKLIaGILEPT----SGRVE----------------VNGRVSALL--EL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 106 MTSLNPAFTlGDQLSEAVMRHQTLSRAEAMTVALQILEKVQI-PAAEMRLKVYphqlSGGMRQRVMIAMALINHPKLLIA 184
Cdd:COG1134   96 GAGFHPELT-GRENIYLNGRLLGLSRKEIDEKFDEIVEFAELgDFIDQPVKTY----SSGMRARLAFAVATAVDPDILLV 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 185 DEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:COG1134  171 DEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIA 235

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

11-221

3.28e-17

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 82.41 E-value: 3.28e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   11 PVLRLQNLNVKFAGSPVsVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREY 90
Cdd:TIGR02868 333 PTLELRDLSAGYPGAPP-VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPL----QGEVTLDGVPVSSLDQDEV 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   91 ANLRG--SELAMIFqepmtslnpAFTLGDQLSEAvmrHQTLSRAEAMTValqiLEKVQ--IPAAE----MRLKVYPH--Q 160
Cdd:TIGR02868 408 RRRVSvcAQDAHLF---------DTTVRENLRLA---RPDATDEELWAA----LERVGlaDWLRAlpdgLDTVLGEGgaR 471

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244  161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLntLKEETGTAVLMITHDL 221
Cdd:TIGR02868 472 LSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVLITHHL 530

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

12-245

3.98e-17

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 79.87 E-value: 3.98e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVkfAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASAR----IVSGEMHFRRHDLRKLSP 87
Cdd:PRK13547   1 MLTADHLHV--ARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGAprgaRVTGDVTLNGEPLAAIDA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 REYANLRgselAMIFQEPmtslNPAFTLGDQLSEAVMRHQTLSRAEAMT-----VALQILEKVQIPAAEMRLKVyphQLS 162
Cdd:PRK13547  79 PRLARLR----AVLPQAA----QPAFAFSAREIVLLGRYPHARRAGALThrdgeIAWQALALAGATALVGRDVT---TLS 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 GGMRQRVMIAMAL---------INHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAV 233
Cdd:PRK13547 148 GGELARVQFARVLaqlwpphdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAM 227

                        250
                 ....*....|..
gi 550714244 234 MYAGQVVEQGSV 245
Cdd:PRK13547 228 LADGAIVAHGAP 239

PRK14243

phosphate transporter ATP-binding protein; Provisional

12-257

4.20e-17

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 79.83 E-value: 4.20e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVkFAGSPVSVlEDISLAVRAGETLALVGESGCGKSiTSLA----LMGLLPaSARiVSGEMHFRRHDL--RKL 85
Cdd:PRK14243  10 VLRTENLNV-YYGSFLAV-KNVWLDIPKNQITAFIGPSGCGKS-TILRcfnrLNDLIP-GFR-VEGKVTFHGKNLyaPDV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 SPREyanLRgSELAMIFQEPmtslNP---------AF---TLG-----DQLSEAVMRHQTLsraeamtvalqiLEKVQip 148
Cdd:PRK14243  85 DPVE---VR-RRIGMVFQKP----NPfpksiydniAYgarINGykgdmDELVERSLRQAAL------------WDEVK-- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 149 aaeMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVA 228
Cdd:PRK14243 143 ---DKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQAARVS 217

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 550714244 229 QQVAVMYA---------GQVVEQGSVEAIFADPQHPYT 257
Cdd:PRK14243 218 DMTAFFNVeltegggryGYLVEFDRTEKIFNSPQQQAT 255

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

7-220

4.25e-17

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 78.99 E-value: 4.25e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   7 KDSTPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSItslalmgLLPASARIVS---GEMHFRRHDLR 83
Cdd:PRK10247   2 QENSPLLQLQNVGYLAGDAKI--LNNISFSLRAGEFKLITGPSGCGKST-------LLKIVASLISptsGTLLFEGEDIS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  84 KLSPREYANlrgsELAMIFQEPMtslnpafTLGDQLSEAV-----MRHQtlsrAEAMTVALQILEKVQIPaaEMRLKVYP 158
Cdd:PRK10247  73 TLKPEIYRQ----QVSYCAQTPT-------LFGDTVYDNLifpwqIRNQ----QPDPAIFLDDLERFALP--DTILTKNI 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHD 220
Cdd:PRK10247 136 AELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

1-265

6.60e-17

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 79.06 E-value: 6.60e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   1 MTTIPFKDSTPVLRlqnlNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGllpasarivsgemhfrRH 80
Cdd:PRK10575   2 QEYTNHSDTTFALR----NVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKS-TLLKMLG----------------RH 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  81 DlrklSPREyanlrGSelAMIFQEPMTSLNpaftlgdqlSEAVMRH-----QTLSRAEAMTV-------------ALQIL 142
Cdd:PRK10575  61 Q----PPSE-----GE--ILLDAQPLESWS---------SKAFARKvaylpQQLPAAEGMTVrelvaigrypwhgALGRF 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 143 -----EKVQIPAAEMRLKVYPHQL----SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTA 213
Cdd:PRK10575 121 gaadrEKVEEAISLVGLKPLAHRLvdslSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLT 200

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 550714244 214 VLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADP--QHPYTIGlMGSIP 265
Cdd:PRK10575 201 VIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGEtlEQIYGIP-MGILP 253

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

15-263

1.11e-16

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 80.07 E-value: 1.11e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGSPVSvlEDISLAVRAGETLALVGESGCGKSITSLALMGLlpasARIVSGEMHFRRHDLRKLSPREyanlR 94
Cdd:PRK11000   6 LRNVTKAYGDVVIS--KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGL----EDITSGDLFIGEKRMNDVPPAE----R 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 GseLAMIFQepmtslnpaftlgdqlSEAVMRHqtLSRAEAMTVALQI--LEKVQIP-----AAEMR-----LKVYPHQLS 162
Cdd:PRK11000  76 G--VGMVFQ----------------SYALYPH--LSVAENMSFGLKLagAKKEEINqrvnqVAEVLqlahlLDRKPKALS 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 163 GGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQ 242
Cdd:PRK11000 136 GGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQV 215

                        250       260
                 ....*....|....*....|.
gi 550714244 243 GSVEAIFADPQHPYTIGLMGS 263
Cdd:PRK11000 216 GKPLELYHYPANRFVAGFIGS 236

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

12-248

1.26e-16

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 78.49 E-value: 1.26e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLL-PASARIVSGEMHFRRHDLRKLSPRey 90
Cdd:PRK10253   5 VARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMtPAHGHVWLDGEHIQHYASKEVARR-- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 anlrgseLAMIFQEpmtslnpAFTLGD-QLSEAVMR----HQTL------SRAEAMTVALQILEKVQIPAAEMrlkvypH 159
Cdd:PRK10253  83 -------IGLLAQN-------ATTPGDiTVQELVARgrypHQPLftrwrkEDEEAVTKAMQATGITHLADQSV------D 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:PRK10253 143 TLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKI 222


                 ....*....
gi 550714244 240 VEQGSVEAI 248
Cdd:PRK10253 223 VAQGAPKEI 231

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

154-256

1.45e-16

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 79.53 E-value: 1.45e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 154 LKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAV 233
Cdd:PRK11144 122 LDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVV 201

                         90       100
                 ....*....|....*....|....
gi 550714244 234 MYAGQVVEQGSVEAIFADPQ-HPY 256
Cdd:PRK11144 202 LEQGKVKAFGPLEEVWASSAmRPW 225

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

18-219

2.03e-16

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 76.93 E-value: 2.03e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  18 LNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIvSGEMHFRRHDL-RKLSPREYANLRGS 96
Cdd:cd03234   11 LKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTT-SGQILFNGQPRkPDQFQKCVAYVRQD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  97 ELamifqepmtsLNPAFTLGDQLSEAVM----RHQTLSRAEAMTVALQILEKVQIPAAEMRLKvyphQLSGGMRQRVMIA 172
Cdd:cd03234   90 DI----------LLPGLTVRETLTYTAIlrlpRKSSDAIRKKRVEDVLLRDLALTRIGGNLVK----GISGGERRRVSIA 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITH 219
Cdd:cd03234  156 VQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLARR-NRIVILTIH 201

PRK13651

cobalt transporter ATP-binding subunit; Provisional

29-251

2.69e-16

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 78.20 E-value: 2.69e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKS--ITSL-ALmgLLPASARI-------------VSGEMHFRRHDLRKLSPREYAN 92
Cdd:PRK13651  22 ALDNVSVEINQGEFIAIIGQTGSGKTtfIEHLnAL--LLPDTGTIewifkdeknkkktKEKEKVLEKLVIQKTRFKKIKK 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRG--SELAMIFQEPMTSLNPAFTLGDQLSEAVmrHQTLSRAEAMTVALQILEKVQIPaaEMRLKVYPHQLSGGMRQRVM 170
Cdd:PRK13651 100 IKEirRRVGVVFQFAEYQLFEQTIEKDIIFGPV--SMGVSKEEAKKRAAKYIELVGLD--ESYLQRSPFELSGGQKRRVA 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:PRK13651 176 LAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDILS 254


                 .
gi 550714244 251 D 251
Cdd:PRK13651 255 D 255

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

4-243

2.74e-16

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 76.80 E-value: 2.74e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   4 IPFKDSTPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASarivSGEMhfrrhdl 82
Cdd:cd03220   12 TYKGGSSSLKKLGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKS-TLLRLLaGIYPPD----SGTV------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  83 rklspreyaNLRGSELAMIfqEPMTSLNPAFTlGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAA-EMRLKVYphql 161
Cdd:cd03220   80 ---------TVRGRVSSLL--GLGGGFNPELT-GRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFiDLPVKTY---- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:cd03220  144 SSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELL-KQGKTVILVSHDPSSIKRLCDRALVLEKGKIRF 222


                 ..
gi 550714244 242 QG 243
Cdd:cd03220  223 DG 224

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

19-254

5.24e-16

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 76.73 E-value: 5.24e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMG--LLPASarivsGEMHFRRHDLRKLSPREYANLRgS 96
Cdd:PRK11831  12 GVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKT-TLLRLIGgqIAPDH-----GEILFDGENIPAMSRSRLYTVR-K 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  97 ELAMIFQEpmTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEmrlKVYPHQLSGGMRQRVMIAMALI 176
Cdd:PRK11831  85 RMSMLFQS--GALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAA---KLMPSELSGGMARRAALARAIA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 177 NHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFADPQH 254
Cdd:PRK11831 160 LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDP 237

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

29-219

9.28e-16

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 73.73 E-value: 9.28e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKsiTSL--ALMGLLPASarivSGEMHFrrhdlrklspreyanLRGSELAMIFQEPM 106
Cdd:cd03223   16 LLKDLSFEIKPGDRLLITGPSGTGK--SSLfrALAGLWPWG----SGRIGM---------------PEGEDLLFLPQRPY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 107 TslnPAFTLGDQLseavmrhqtlsraeamtvalqilekvqipaaemrlkVYP--HQLSGGMRQRVMIAMALINHPKLLIA 184
Cdd:cd03223   75 L---PLGTLREQL------------------------------------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFL 115

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 550714244 185 DEPTTALDVTIQAQILALLNTLkeetGTAVLMITH 219
Cdd:cd03223  116 DEATSALDEESEDRLYQLLKEL----GITVISVGH 146

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

3-248

3.35e-15

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 75.25 E-value: 3.35e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   3 TIPFKDSTPVLRLQNLNVKFAGSPVS-----VLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGemhf 77
Cdd:PRK13536  25 GISEAKASIPGSMSTVAIDLAGVSKSygdkaVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITV---- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  78 rrhdLRKLSPREyANLRGSELAMIFQepMTSLNPAFTLGDQLSeAVMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVY 157
Cdd:PRK13536 101 ----LGVPVPAR-ARLARARIGVVPQ--FDNLDLEFTVRENLL-VFGRYFGMSTREIEAVIPSLLEFARL---ESKADAR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 158 PHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAG 237
Cdd:PRK13536 170 VSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAG 248

                        250
                 ....*....|.
gi 550714244 238 QVVEQGSVEAI 248
Cdd:PRK13536 249 RKIAEGRPHAL 259

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

28-255

3.73e-15

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 76.24 E-value: 3.73e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   28 SVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLP-----ASARIVSGemhfRRHDLRKLSPREyanlrgselAMIF 102
Cdd:TIGR00955  39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPkgvkgSGSVLLNG----MPIDAKEMRAIS---------AYVQ 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  103 QEPMtsLNPAFTLGDQLS-EAVMR-HQTLSRAEAMTVALQILEKVQI-PAAEMRLKVyPHQ---LSGGMRQRVMIAMALI 176
Cdd:TIGR00955 106 QDDL--FIPTLTVREHLMfQAHLRmPRRVTKKEKRERVDEVLQALGLrKCANTRIGV-PGRvkgLSGGERKRLAFASELL 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  177 NHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVE---AIFADPQ 253
Cdd:TIGR00955 183 TDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDqavPFFSDLG 262


                  ..
gi 550714244  254 HP 255
Cdd:TIGR00955 263 HP 264

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

9-252

9.15e-15

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 73.10 E-value: 9.15e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivsGEMHFRRHDLRKLSPR 88
Cdd:PRK11300   2 SQPLLSVSGLMMRFGG--LLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTG----GTILLRGQHIEGLPGH 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANL---RGSELAMIFQEpMTSLNPAFtlgdqlseaVMRHQTL----------------SRAEAMTVALQILEKVQIPA 149
Cdd:PRK11300  76 QIARMgvvRTFQHVRLFRE-MTVIENLL---------VAQHQQLktglfsgllktpafrrAESEALDRAATWLERVGLLE 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 150 AEMRlkvYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQ 229
Cdd:PRK11300 146 HANR---QAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISD 222

                        250       260
                 ....*....|....*....|...
gi 550714244 230 QVAVMYAGQVVEQGSVEAIFADP 252
Cdd:PRK11300 223 RIYVVNQGTPLANGTPEEIRNNP 245

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

9-250

9.52e-15

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 73.69 E-value: 9.52e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGL-LPASARI-VSGEMHFRRhdlrkls 86
Cdd:PRK13537   4 SVAPIDFRNVEKRYGDK--LVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLtHPDAGSIsLCGEPVPSR------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 preyANLRGSELAMIFQepMTSLNPAFTLGDQLsEAVMRHQTLSRAEAMTVALQILEKVQIpaaEMRLKVYPHQLSGGMR 166
Cdd:PRK13537  75 ----ARHARQRVGVVPQ--FDNLDPDFTVRENL-LVFGRYFGLSAAAARALVPPLLEFAKL---ENKADAKVGELSGGMK 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 167 QRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVE 246
Cdd:PRK13537 145 RRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLL-ARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPH 223


                 ....
gi 550714244 247 AIFA 250
Cdd:PRK13537 224 ALIE 227

ycf16

CHL00131

sulfate ABC transporter protein; Validated

9-246

1.02e-14

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 72.75 E-value: 1.02e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGlLPASaRIVSGEMHFRRHDLRKLSPR 88
Cdd:CHL00131   4 NKPILEIKNLHASVNENEI--LKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG-HPAY-KILEGDILFKGESILDLEPE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLrGSELAmiFQEPMTSlnPAFTLGDQLS---EAVMRHQTLSRAEAMTVALQILEKVQIpaaemrLKVYPHQL---- 161
Cdd:CHL00131  80 ERAHL-GIFLA--FQYPIEI--PGVSNADFLRlayNSKRKFQGLPELDPLEFLEIINEKLKL------VGMDPSFLsrnv 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 162 ----SGGMRQRVMI-AMALINhPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITHD---LGVVaeVAQQVAV 233
Cdd:CHL00131 149 negfSGGEKKRNEIlQMALLD-SELAILDETDSGLDIDALKIIAEGINKLM-TSENSIILITHYqrlLDYI--KPDYVHV 224

                        250
                 ....*....|...
gi 550714244 234 MYAGQVVEQGSVE 246
Cdd:CHL00131 225 MQNGKIIKTGDAE 237

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

160-267

1.45e-14

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 71.81 E-value: 1.45e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVaVMYAGQV 239
Cdd:TIGR03771 113 ELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELFIELAGA-GTAILMTTHDLAQAMATCDRV-VLLNGRV 190

                          90       100       110
                  ....*....|....*....|....*....|
gi 550714244  240 VEQGsVEAIFADPQhPY--TIGLMGSIPSL 267
Cdd:TIGR03771 191 IADG-TPQQLQDPA-PWmtTFGVSDSSPLL 218

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

9-241

1.52e-14

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 74.18 E-value: 1.52e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRhdlrklSPR 88
Cdd:PRK11288   1 SSPYLSFDGIGKTFPG--VKALDDISFDCRAGQVHALMGENGAGKS----TLLKILSGNYQPDAGSILIDG------QEM 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLR---GSELAMIFQEpmTSLNPAFT------LGdQLSEavmRHQTLSRAEAMTVALQILEkvqipaaEMRLKVYPH 159
Cdd:PRK11288  69 RFASTTaalAAGVAIIYQE--LHLVPEMTvaenlyLG-QLPH---KGGIVNRRLLNYEAREQLE-------HLGVDIDPD 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 160 Q----LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:PRK11288 136 TplkyLSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFK 214


                 ....*.
gi 550714244 236 AGQVVE 241
Cdd:PRK11288 215 DGRYVA 220

PRK15056

manganese/iron ABC transporter ATP-binding protein;

28-249

1.64e-14

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 72.61 E-value: 1.64e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  28 SVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLRKLspreyanLRGSELAMIFQEPMT 107
Cdd:PRK15056  21 TALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFV----RLASGKISILGQPTRQA-------LQKNLVAYVPQSEEV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 SLNPAFTLGDQLSEAVMRHQT-LSRAEAmtvalQILEKVQIPAAEMRLKVYPH----QLSGGMRQRVMIAMALINHPKLL 182
Cdd:PRK15056  90 DWSFPVLVEDVVMMGRYGHMGwLRRAKK-----RDRQIVTAALARVDMVEFRHrqigELSGGQKKRVFLARAIAQQGQVI 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 183 IADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAqQVAVMYAGQVVEQGSVEAIF 249
Cdd:PRK15056 165 LLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFC-DYTVMVKGTVLASGPTETTF 229

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

34-251

5.72e-14

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 72.35 E-value: 5.72e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  34 SLAVRAGETLALVGESGCGKSITSLALMGLLPasarIVSGEmhfRRHDLRKLspreyANLRGSELAMIfqepmtslnpaf 113
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGELP----LLSGE---RQSQFSHI-----TRLSFEQLQKL------------ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 114 tlgdqLSEAVMRHQT--LSRAE---AMTVALQILEKVQIPAAEMRLKVYPH----------QLSGGMRQRVMIAMALINH 178
Cdd:PRK10938  79 -----VSDEWQRNNTdmLSPGEddtGRTTAEIIQDEVKDPARCEQLAQQFGitalldrrfkYLSTGETRKTLLCQALMSE 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550714244 179 PKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMIT--HDlgvVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PRK10938 154 PDLLILDEPFDGLDVASRQQLAELLASLHQSGITLVLVLNrfDE---IPDFVQFAGVLADCTLAETGEREEILQQ 225

PRK10762

D-ribose transporter ATP binding protein; Provisional

18-250

6.99e-14

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 72.34 E-value: 6.99e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  18 LNVK-FAGSPVsvlEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPRE-YANlrG 95
Cdd:PRK10762 258 LKVDnLSGPGV---NDVSFTLRKGEILGVSGLMGAGRT----ELMKVLYGALPRTSGYVTLDGHEVVTRSPQDgLAN--G 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  96 ----SE--------LAMIFQEPM--TSLnpaftlgDQLSEAV--MRHQtlsrAEAMTVALQI-LEKVQIPAAEMRLKVyp 158
Cdd:PRK10762 329 ivyiSEdrkrdglvLGMSVKENMslTAL-------RYFSRAGgsLKHA----DEQQAVSDFIrLFNIKTPSMEQAIGL-- 395

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 hqLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:PRK10762 396 --LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGR 472

                        250
                 ....*....|....*..
gi 550714244 239 V-----VEQGSVEAIFA 250
Cdd:PRK10762 473 IsgeftREQATQEKLMA 489

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

12-239

7.33e-14

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 72.16 E-value: 7.33e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   12 VLRLQNLNVKFAGSP-VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivSGEMHFrrhDLRKLSPREY 90
Cdd:TIGR02633 257 ILEARNLTCWDVINPhRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKF---EGNVFI---NGKPVDIRNP 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   91 ANLRGSELAMIFQE-PMTSLNPAFTLGDQLSEAVM-RHQTLSRAEAMTVALQILEKVQipaaemRLKV---YPH----QL 161
Cdd:TIGR02633 331 AQAIRAGIAMVPEDrKRHGIVPILGVGKNITLSVLkSFCFKMRIDAAAELQIIGSAIQ------RLKVktaSPFlpigRL 404

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244  162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:TIGR02633 405 SGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

12-250

1.50e-13

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 71.22 E-value: 1.50e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   12 VLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGL-LPASARIVSGEMHFRRHDLRKLS---- 86
Cdd:TIGR01842 316 HLSVENVTIVPPGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIwPPTSGSVRLDGADLKQWDRETFGkhig 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   87 --PREYANLRGSELAMI--FQEPMTSlnpaftlgdqlsEAVMRHQTLSRAEAMTVAL-QILEKVQIPAAEmrlkvyphQL 161
Cdd:TIGR01842 396 ylPQDVELFPGTVAENIarFGENADP------------EKIIEAAKLAGVHELILRLpDGYDTVIGPGGA--------TL 455

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLmITHDLGVVaEVAQQVAVMYAGQVVE 241
Cdd:TIGR01842 456 SGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKARGITVVV-ITHRPSLL-GCVDKILVLQDGRIAR 533


                  ....*....
gi 550714244  242 QGSVEAIFA 250
Cdd:TIGR01842 534 FGERDEVLA 542

PTZ00265

multidrug resistance protein (mdr1); Provisional

14-252

1.61e-13

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 71.60 E-value: 1.61e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   14 RLQNLNVKF---AGSPVSVLEDISLAVRAGETLALVGESGCGKSiTSLALMGLL--PASARIVSGEMH---------FR- 78
Cdd:PTZ00265  382 KIQFKNVRFhydTRKDVEIYKDLNFTLTEGKTYAFVGESGCGKS-TILKLIERLydPTEGDIIINDSHnlkdinlkwWRs 460

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   79 --------------------RHDLRKLSPREYANLRGSELAMIFQEPMTSLNPAF-------------TLGDQLSEAVMR 125
Cdd:PTZ00265  461 kigvvsqdpllfsnsiknniKYSLYSLKDLEALSNYYNEDGNDSQENKNKRNSCRakcagdlndmsntTDSNELIEMRKN 540

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  126 HQTLSRAEAMTVALQILEKVQIPAA----EMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILA 201
Cdd:PTZ00265  541 YQTIKDSEVVDVSKKVLIHDFVSALpdkyETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQK 620

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 550714244  202 LLNTLKEETGTAVLMITHDLGVVaEVAQQVAVMYAGQVVEQGSVEAIFADP 252
Cdd:PTZ00265  621 TINNLKGNENRITIIIAHRLSTI-RYANTIFVLSNRERGSTVDVDIIGEDP 670

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

10-246

1.63e-13

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 71.24 E-value: 1.63e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPRE 89
Cdd:PRK15439   9 PPLLCARSISKQYSG--VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPD----SGTLEIGGNPCARLTPAK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 YANLrgsELAMIFQEPMtsLNPAFTLGDQLSEAVMRHQ-TLSRAEAMTVALQILEKVQIPAAEmrLKVYPHQLsggmrqr 168
Cdd:PRK15439  83 AHQL---GIYLVPQEPL--LFPNLSVKENILFGLPKRQaSMQKMKQLLAALGCQLDLDSSAGS--LEVADRQI------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDV----TIQAQILALLNtlkeeTGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:PRK15439 149 VEILRGLMRDSRILILDEPTASLTPaeteRLFSRIRELLA-----QGVGIVFISHKLPEIRQLADRISVMRDGTIALSGK 223


                 ..
gi 550714244 245 VE 246
Cdd:PRK15439 224 TA 225

PRK10762

D-ribose transporter ATP binding protein; Provisional

10-251

2.44e-13

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 70.42 E-value: 2.44e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivsGEMHFRRHDLRKLSPRE 89
Cdd:PRK10762   2 QALLQLKGIDKAFPG--VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDA----GSILYLGKEVTFNGPKS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanlrgSELA---MIFQEpmtsLN--PAFTLGDQL---SEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKvypHQL 161
Cdd:PRK10762  76 ------SQEAgigIIHQE----LNliPQLTIAENIflgREFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLV---GEL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:PRK10762 143 SIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQFIA 221

                        250
                 ....*....|
gi 550714244 242 QGSVEAIFAD 251
Cdd:PRK10762 222 EREVADLTED 231

PRK13549

xylose transporter ATP-binding subunit; Provisional

12-239

2.52e-13

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 70.34 E-value: 2.52e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSP-VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASArivSGEMHFRRHDLRKLSPREy 90
Cdd:PRK13549 259 ILEVRNLTAWDPVNPhIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRW---EGEIFIDGKPVKIRNPQQ- 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRGseLAMIFQE-------PMTSLNPAFTLG--DQLSeavmRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVypHQL 161
Cdd:PRK13549 335 AIAQG--IAMVPEDrkrdgivPVMGVGKNITLAalDRFT----GGSRIDDAAELKTILESIQRLKVKTASPELAI--ARL 406

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQV 239
Cdd:PRK13549 407 SGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKL 483

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

24-221

4.50e-13

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 67.36 E-value: 4.50e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  24 GSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLpasaRIVSGEMHFRRHDLRKLSPREYANLRGSELAMIFQ 103
Cdd:cd03290   11 GSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEM----QTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 104 EPM---TSLNPAFTLGDQLSEavMRHQTLSRAEAMTVALQIL---EKVQIPAAEMrlkvyphQLSGGMRQRVMIAMALIN 177
Cdd:cd03290   87 KPWllnATVEENITFGSPFNK--QRYKAVTDACSLQPDIDLLpfgDQTEIGERGI-------NLSGGQRQRICVARALYQ 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 550714244 178 HPKLLIADEPTTALDVTIQAQIL--ALLNTLKEETGTAVLmITHDL 221
Cdd:cd03290  158 NTNIVFLDDPFSALDIHLSDHLMqeGILKFLQDDKRTLVL-VTHKL 202

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

32-241

7.96e-13

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 69.04 E-value: 7.96e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  32 DISLAVRAGETLALVGESGCGKSITSLALMGLLPasarIVSGEMHFRRHDLRKLSPREyANLRGseLAMIFQEPM-TSLN 110
Cdd:PRK09700 281 DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDK----RAGGEIRLNGKDISPRSPLD-AVKKG--MAYITESRRdNGFF 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 111 PAFTLGDQLseAVMRHQTLSR----------AEAMTVALQILEKVQIPAAEMRLKVypHQLSGGMRQRVMIAMALINHPK 180
Cdd:PRK09700 354 PNFSIAQNM--AISRSLKDGGykgamglfheVDEQRTAENQRELLALKCHSVNQNI--TELSGGNQQKVLISKWLCCCPE 429

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 181 LLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVE 241
Cdd:PRK09700 430 VIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

29-224

9.35e-12

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 63.15 E-value: 9.35e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKsiTSL--ALMGLLPAsariVSGEMHFRRHDLRKLSPreyanLRGSELAMIFQEPm 106
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGK--TTLlrILAGLLRP----DSGEVRWNGTPLAEQRD-----EPHENILYLGHLP- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  107 tSLNPAFTLGDQLSEAVMRHQTLSRAeamtvALQILEKVQIPAAEMRLKvypHQLSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:TIGR01189  83 -GLKPELSALENLHFWAAIHGGAQRT-----IEDALAAVGLTGFEDLPA---AQLSAGQQRRLALARLWLSRRPLWILDE 153

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 550714244  187 PTTALDVTIQAQILALLnTLKEETGTAVLMITH-DLGVV 224
Cdd:TIGR01189 154 PTTALDKAGVALLAGLL-RAHLARGGIVLLTTHqDLGLV 191

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

27-248

2.20e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 63.99 E-value: 2.20e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  27 VSVLEDISLAVRAGETLALVGESGCGKSitslalMGLLPASariVSGEMHFRRhdlrklsPREY----ANLRGSELAMIF 102
Cdd:NF000106  26 VKAVDGVDLDVREGTVLGVLGP*GAA**------RGALPAH---V*GPDAGRR-------PWRF*twcANRRALRRTIG* 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 103 QEPMTSLNPAFTLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVyphQLSGGMRQRVMIAMALINHPKLL 182
Cdd:NF000106  90 HRPVR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAA---KYSGGMRRRLDLAASMIGRPAVL 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 183 IADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:NF000106 167 YLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

29-231

2.41e-11

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 62.13 E-value: 2.41e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSgemhfrrhdlrkLSPREYANLRGSelamiFQEPMTS 108
Cdd:cd03231   15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVL------------LNGGPLDFQRDS-----IARGLLY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 LNPAFTLGDQLSeAVMRHQTLSRAEAMTVALQILEKVQIPAAEMRLKvypHQLSGGMRQRVMIAMALINHPKLLIADEPT 188
Cdd:cd03231   78 LGHAPGIKTTLS-VLENLRFWHADHSDEQVEEALARVGLNGFEDRPV---AQLSAGQQRRVALARLLLSGRPLWILDEPT 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 550714244 189 TALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQV 231
Cdd:cd03231  154 TALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGLSEAGAREL 196

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

8-246

4.42e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 64.26 E-value: 4.42e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244     8 DSTPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITslalMGLLPASARIVSGEmhfrrhdlrklsp 87
Cdd:TIGR01257 1933 NKTDILRLNELTKVYSGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTT----FKMLTGDTTVTSGD------------- 1995

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    88 reyANLRGSELAMIFQEPMTSLN--PAFTLGDQLSEAvmRHQTLSRAEAMTVALQILEKV-QIPAAEMRLKVYPHQL--- 161
Cdd:TIGR01257 1996 ---ATVAGKSILTNISDVHQNMGycPQFDAIDDLLTG--REHLYLYARLRGVPAEEIEKVaNWSIQSLGLSLYADRLagt 2070

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   162 -SGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:TIGR01257 2071 ySGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQ 2149


                   ....*.
gi 550714244   241 EQGSVE 246
Cdd:TIGR01257 2150 CLGTIQ 2155

PRK11147

ABC transporter ATPase component; Reviewed

12-220

4.48e-11

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 63.82 E-value: 4.48e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSiTSLALM--GLLPASARIVSGEmhfrrhdlrKLspre 89
Cdd:PRK11147 319 VFEMENVNYQIDGK--QLVKDFSAQVQRGDKIALIGPNGCGKT-TLLKLMlgQLQADSGRIHCGT---------KL---- 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  90 yanlrgsELAMiFQEPMTSLNPAFTLGDQLSEA---VM-----RHqtlsraeamtvALQILEKVQIPAAEMRLKVypHQL 161
Cdd:PRK11147 383 -------EVAY-FDQHRAELDPEKTVMDNLAEGkqeVMvngrpRH-----------VLGYLQDFLFHPKRAMTPV--KAL 441

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 162 SGGMRQRVMIAMALINHPKLLIADEPTTALDVtiqaQILALLNTLKEE-TGTaVLMITHD 220
Cdd:PRK11147 442 SGGERNRLLLARLFLKPSNLLILDEPTNDLDV----ETLELLEELLDSyQGT-VLLVSHD 496

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

29-223

5.15e-11

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 61.43 E-value: 5.15e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPAsariVSGEMHFRRHDLRKLSPREYANLRGSELAMifqepmt 107
Cdd:PRK13539  17 LFSGLSFTLAAGEALVLTGPNGSGKT-TLLRLIaGLLPP----AAGTIKLDGGDIDDPDVAEACHYLGHRNAM------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 slNPAFTLGDQLS-EAVMRHQTLSRAEAMTVALQILEKVQIPAAEmrlkvyphqLSGGMRQRVMIAMALINHPKLLIADE 186
Cdd:PRK13539  85 --KPALTVAENLEfWAAFLGGEELDIAAALEAVGLAPLAHLPFGY---------LSAGQKRRVALARLLVSNRPIWILDE 153

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 550714244 187 PTTALDVTIQAQILALLNTlKEETGTAVLMITH-DLGV 223
Cdd:PRK13539 154 PTAALDAAAVALFAELIRA-HLAQGGIVIAATHiPLGL 190

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

22-252

8.00e-11

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 62.81 E-value: 8.00e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  22 FAGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREYAnlrgSELAMI 101
Cdd:PRK10789 323 YPQTDHPALENVNFTLKPGQMLGICGPTGSGKS----TLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWR----SRLAVV 394

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 102 FQEPMTslnpaftlgdqLSEAVMRHQTLSRAEAmtVALQILEKVQIPAAE---MRL-KVYPHQ-------LSGGMRQRVM 170
Cdd:PRK10789 395 SQTPFL-----------FSDTVANNIALGRPDA--TQQEIEHVARLASVHddiLRLpQGYDTEvgergvmLSGGQKQRIS 461

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 171 IAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:PRK10789 462 IARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGE--GRTVIISAHRLSALTE-ASEILVMQHGHIAQRGNHDQLAQ 538


                 ..
gi 550714244 251 DP 252
Cdd:PRK10789 539 QS 540

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

37-235

9.69e-11

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 61.23 E-value: 9.69e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  37 VRAGETLALVGESGCGKSiTSLalmgllpasaRIVSGEM--HFRRHDlrklSPREY----ANLRGSELamifQEPMTSLn 110
Cdd:cd03236   23 PREGQVLGLVGPNGIGKS-TAL----------KILAGKLkpNLGKFD----DPPDWdeilDEFRGSEL----QNYFTKL- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 111 paftLGDQLSeAVMRHQTLSR--AEAMTVALQILEKVQ--------IPAAEMR--LKVYPHQLSGGMRQRVMIAMALINH 178
Cdd:cd03236   83 ----LEGDVK-VIVKPQYVDLipKAVKGKVGELLKKKDergkldelVDQLELRhvLDRNIDQLSGGELQRVAIAAALARD 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 179 PKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:cd03236  158 ADFYFFDEPSSYLDIKQRLNAARLIRELAED-DNYVLVVEHDLAVLDYLSDYIHCLY 213

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

29-244

1.02e-10

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 63.04 E-value: 1.02e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSpreYANLRgSELAMIFQEPM-- 106
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESA----EGEIIIDGLNIAKIG---LHDLR-FKITIIPQDPVlf 1372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   107 -----TSLNPaftLGDQLSEAVMRHQTLSRAEAMTVALQilEKVQIPAAEMrlkvyPHQLSGGMRQRVMIAMALINHPKL 181
Cdd:TIGR00957 1373 sgslrMNLDP---FSQYSDEEVWWALELAHLKTFVSALP--DKLDHECAEG-----GENLSVGQRQLVCLARALLRKTKI 1442

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244   182 LIADEPTTALDVTIQAQILALLNTLKEEtgTAVLMITHDLGVVAEVAqQVAVMYAGQVVEQGS 244
Cdd:TIGR00957 1443 LVLDEATAAVDLETDNLIQSTIRTQFED--CTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGA 1502

PRK09984

phosphonate ABC transporter ATP-binding protein;

12-247

1.41e-10

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 60.80 E-value: 1.41e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASaRIVSGEMHFRRHDLRKlSPREYA 91
Cdd:PRK09984   4 IIRVEKLAKTFNQH--QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGD-KSAGSHIELLGRTVQR-EGRLAR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGS--ELAMIFQEpmtslnpaFTLGDQLS--EAVMRH------------QTLSRAEAMTvALQILEKVQIPAaemrlk 155
Cdd:PRK09984  80 DIRKSraNTGYIFQQ--------FNLVNRLSvlENVLIGalgstpfwrtcfSWFTREQKQR-ALQALTRVGMVH------ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 156 vYPHQ----LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQV 231
Cdd:PRK09984 145 -FAHQrvstLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERI 223

                        250
                 ....*....|....*.
gi 550714244 232 AVMYAGQVVEQGSVEA 247
Cdd:PRK09984 224 VALRQGHVFYDGSSQQ 239

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

31-226

1.44e-10

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 59.82 E-value: 1.44e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  31 EDISLAVRAGETLALVGESGCGKsiTSL--ALMGLLPASArivsGEMHFRRHDLRKLSPREYANL------RG--SELAm 100
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGK--TSLlrILAGLARPDA----GEVLWQGEPIRRQRDEYHQDLlylghqPGikTELT- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 101 ifqePMTSLNPAFTLGDQLSEAVMRhqtlsraeamtvalQILEKV------QIPAaemrlkvypHQLSGGMRQRVMIAMA 174
Cdd:PRK13538  91 ----ALENLRFYQRLHGPGDDEALW--------------EALAQVglagfeDVPV---------RQLSAGQQRRVALARL 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 550714244 175 LINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAE 226
Cdd:PRK13538 144 WLTRAPLWILDEPFTAIDKQGVARLEALLAQHAEQGGMVILTTHQDLPVASD 195

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

31-240

1.76e-10

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 61.85 E-value: 1.76e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  31 EDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLSPREyANLRGselAMIFQEPMTSLN 110
Cdd:PRK11288 270 EPISFSVRAGEIVGLFGLVGAGRS----ELMKLLYGATRRTAGQVYLDGKPIDIRSPRD-AIRAG---IMLCPEDRKAEG 341

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 111 --PAFTLGDQLSEAVMRHQTL------SRAEAMTVALQI-LEKVQIPAAEMRLKvyphQLSGGMRQRVMIAMALINHPKL 181
Cdd:PRK11288 342 iiPVHSVADNINISARRHHLRagclinNRWEAENADRFIrSLNIKTPSREQLIM----NLSGGNQQKAILGRWLSEDMKV 417

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244 182 LIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVV 240
Cdd:PRK11288 418 ILLDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGRIA 475

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

9-243

7.98e-10

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 57.66 E-value: 7.98e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   9 STPVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARiVSGEMHFRRHDlrklsPR 88
Cdd:cd03233    2 STLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVS-VEGDIHYNGIP-----YK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  89 EYANLRGSELAMIFQEpmtslnpaftlgDqlseavmRHQTLsraeaMTVAlQILEKvqipAAEMRLKVYPHQLSGGMRQR 168
Cdd:cd03233   76 EFAEKYPGEIIYVSEE------------D-------VHFPT-----LTVR-ETLDF----ALRCKGNEFVRGISGGERKR 126

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 169 VMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVA-EVAQQVAVMYAGQVVEQG 243
Cdd:cd03233  127 VSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIyDLFDKVLVLYEGRQIYYG 202

PRK13540

cytochrome c biogenesis protein CcmA; Provisional

12-219

1.87e-09

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 56.50 E-value: 1.87e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKlspreya 91
Cdd:PRK13540   1 MLDVIELDFDYHDQPL--LQQISFHLPAGGLLHLKGSNGAGKT----TLLKLIAGLLNPEKGEILFERQSIKK------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  92 NLRGSELAMIFQEPMTSLNPAFTLgdqlseavmRHQTLSRAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRVMI 171
Cdd:PRK13540  68 DLCTYQKQLCFVGHRSGINPYLTL---------RENCLYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVAL 138

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 550714244 172 AMALINHPKLLIADEPTTALDvtiQAQILALLNTLKE--ETGTAVLMITH 219
Cdd:PRK13540 139 LRLWMSKAKLWLLDEPLVALD---ELSLLTIITKIQEhrAKGGAVLLTSH 185

PLN03232

ABC transporter C family member; Provisional

29-250

1.87e-09

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 59.22 E-value: 1.87e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSitslalmGLLPASARIVS---GEMHFRRHDLRKLSpreYANLRgSELAMIFQEP 105
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKS-------SMLNALFRIVElekGRIMIDDCDVAKFG---LTDLR-RVLSIIPQSP 1319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  106 -MTSLNPAFTLgDQLSEavmrHQTLSRAEAMTVAlQILEKVQIPAAEMRLKVYP--HQLSGGMRQRVMIAMALINHPKLL 182
Cdd:PLN03232 1320 vLFSGTVRFNI-DPFSE----HNDADLWEALERA-HIKDVIDRNPFGLDAEVSEggENFSVGQRQLLSLARALLRRSKIL 1393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244  183 IADEPTTALDVTIQAQIlalLNTLKEE-TGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSVEAIFA 250
Cdd:PLN03232 1394 VLDEATASVDVRTDSLI---QRTIREEfKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLS 1458

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

15-250

2.09e-09

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.80 E-value: 2.09e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    15 LQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHfrrhdlrklspreyanLR 94
Cdd:TIGR00957  639 VHNATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKS----SLLSALLAEMDKVEGHVH----------------MK 698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    95 GSeLAMIFQEPMT---SLNPAFTLGDQLSEAvmRHQTLSRAEAMTVALQIL---EKVQIPAAEMrlkvyphQLSGGMRQR 168
Cdd:TIGR00957  699 GS-VAYVPQQAWIqndSLRENILFGKALNEK--YYQQVLEACALLPDLEILpsgDRTEIGEKGV-------NLSGGQKQR 768

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   169 VMIAMALINHPKLLIADEPTTALDVTIQAQI----LALLNTLKEETGtavLMITHDLGVVAEVaQQVAVMYAGQVVEQGS 244
Cdd:TIGR00957  769 VSLARAVYSNADIYLFDDPLSAVDAHVGKHIfehvIGPEGVLKNKTR---ILVTHGISYLPQV-DVIIVMSGGKISEMGS 844


                   ....*.
gi 550714244   245 VEAIFA 250
Cdd:TIGR00957  845 YQELLQ 850

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

11-251

2.28e-09

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 56.81 E-value: 2.28e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLNVKFAgsPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRHDLRKLsprEY 90
Cdd:PRK11614   4 VMLSFDKVSAHYG--KIQALHEVSLHINQGEIVTLIGANGAGKT----TLLGTLCGDPRATSGRIVFDGKDITDW---QT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  91 ANLRGSELAM------IFQEPMTSLNPAftLGDQLSEAVMRHQTLSRAEAMTVALQilEKVQIPAAEMrlkvyphqlSGG 164
Cdd:PRK11614  75 AKIMREAVAIvpegrrVFSRMTVEENLA--MGGFFAERDQFQERIKWVYELFPRLH--ERRIQRAGTM---------SGG 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGS 244
Cdd:PRK11614 142 EQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVLEDT 220


                 ....*..
gi 550714244 245 VEAIFAD 251
Cdd:PRK11614 221 GDALLAN 227

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

29-238

7.03e-09

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 55.17 E-value: 7.03e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSitSLaLMGLLpasarivsGEMHfRRHDLRKLSPReyanlrgseLAMIFQEPM-- 106
Cdd:cd03250   20 TLKDINLEVPKGELVAIVGPVGSGKS--SL-LSALL--------GELE-KLSGSVSVPGS---------IAYVSQEPWiq 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 107 -TSL--NPAFtlGDQLSEAvmRHQTLSRAEAMTVALQILekvqipaaemrlkvyPHQ-----------LSGGMRQRVMIA 172
Cdd:cd03250   79 nGTIreNILF--GKPFDEE--RYEKVIKACALEPDLEIL---------------PDGdlteigekginLSGGQKQRISLA 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 173 MALINHPKLLIADEPTTALDVTIQAQIL--ALLNTLKEetGTAVLMITHDLGVVAEvAQQVAVMYAGQ 238
Cdd:cd03250  140 RAVYSDADIYLLDDPLSAVDAHVGRHIFenCILGLLLN--NKTRILVTHQLQLLPH-ADQIVVLDNGR 204

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

12-250

8.59e-09

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 57.06 E-value: 8.59e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  12 VLRLQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLpASARIV--------SGEMHFRRHdLR 83
Cdd:NF033858   1 VARLEGVSHRYGK--TVALDDVSLDIPAGCMVGLIGPDGVGKS----SLLSLI-AGARKIqqgrvevlGGDMADARH-RR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  84 KLSPReyanlrgselamIfqepmtslnpAFT---LGDQLseavmrHQTLSraeamtvalqILEKVQ-------IPAAEMR 153
Cdd:NF033858  73 AVCPR------------I----------AYMpqgLGKNL------YPTLS----------VFENLDffgrlfgQDAAERR 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 154 LKV---------YPH------QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEET-GTAVLmi 217
Cdd:NF033858 115 RRIdellratglAPFadrpagKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVL-- 192

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 550714244 218 thdlgvVA----EVAQQ---VAVMYAGQVVEQGSVEAIFA 250
Cdd:NF033858 193 ------VAtaymEEAERfdwLVAMDAGRVLATGTPAELLA 226

ABCC_SUR2

cd03288

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...

13-258

9.29e-09

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 55.30 E-value: 9.29e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPasarIVSGEMHFRRHDLRKLSpreYAN 92
Cdd:cd03288   20 IKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVD----IFDGKIVIDGIDISKLP---LHT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 LRgSELAMIFQEPMT-------SLNPAFTLGD-QLSEAVMRHQTLSRAEAMTVAlqiLEKVQIPAAEmrlkvyphQLSGG 164
Cdd:cd03288   93 LR-SRLSIILQDPILfsgsirfNLDPECKCTDdRLWEALEIAQLKNMVKSLPGG---LDAVVTEGGE--------NFSVG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDvtiqaqiLALLNTLKEETGTA-----VLMITHDLGVVAEvAQQVAVMYAGQV 239
Cdd:cd03288  161 QRQLFCLARAFVRKSSILIMDEATASID-------MATENILQKVVMTAfadrtVVTIAHRVSTILD-ADLVLVLSRGIL 232

                        250
                 ....*....|....*....
gi 550714244 240 VEQGSVEAIFADPQHPYTI 258
Cdd:cd03288  233 VECDTPENLLAQEDGVFAS 251

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

29-219

1.03e-08

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 54.96 E-value: 1.03e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSITSLALMGLL---PASARIVSGEMHFrrhdlrklspreyanlrGSELAMIfqep 105
Cdd:COG2401   45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgtPVAGCVDVPDNQF-----------------GREASLI---- 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 106 mtslnpaftlgDQLSeavmrhqtlsRAEAMTVALQILEKVQIPAAEMRLKVYPHqLSGGMRQRVMIAMALINHPKLLIAD 185
Cdd:COG2401  104 -----------DAIG----------RKGDFKDAVELLNAVGLSDAVLWLRRFKE-LSTGQKFRFRLALLLAERPKLLVID 161

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 550714244 186 EPTTALDVTiQAQILAL-LNTLKEETGTAVLMITH 219
Cdd:COG2401  162 EFCSHLDRQ-TAKRVARnLQKLARRAGITLVVATH 195

PLN03211

ABC transporter G-25; Provisional

28-243

4.85e-08

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 54.50 E-value: 4.85e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  28 SVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPAS---ARIVSGEMHFRRHDLRKLspreyanlrgselAMIFQE 104
Cdd:PLN03211  82 TILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnftGTILANNRKPTKQILKRT-------------GFVTQD 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 105 PMtsLNPAFTLGDQLSE-AVMR-HQTLSRAEAMTVALQILEKVQIPAAEMRL--KVYPHQLSGGMRQRVMIAMALINHPK 180
Cdd:PLN03211 149 DI--LYPHLTVRETLVFcSLLRlPKSLTKQEKILVAESVISELGLTKCENTIigNSFIRGISGGERKRVSIAHEMLINPS 226

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714244 181 LLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQG 243
Cdd:PLN03211 227 LLILDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFG 289

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

136-253

6.40e-08

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 51.80 E-value: 6.40e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 136 TVALQILEKVQIPAAE------MRLKVYPH--QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLK 207
Cdd:cd03222   39 TTAVKILAGQLIPNGDndewdgITPVYKPQyiDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLS 118

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 550714244 208 EETGTAVLMITHDLGVVAEVAQQVAVMYAgqvveQGSVEAIFADPQ 253
Cdd:cd03222  119 EEGKKTALVVEHDLAVLDYLSDRIHVFEG-----EPGVYGIASQPK 159

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

5-192

6.46e-08

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 53.98 E-value: 6.46e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   5 PFKDSTPVLRLQNLNVKFaGSPVSVlEDISLAVRAGETLALVGESGCGKSITSLALMGLLPAS---ARIVSGEMHFRRHD 81
Cdd:NF033858 259 ADDDDEPAIEARGLTMRF-GDFTAV-DHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASegeAWLFGQPVDAGDIA 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  82 LRK--------------LSPREyaNLrgsEL-AMIFQEPmtslnpaftlGDQLSEAVmrHQTLSRAEamtvalqiLEKVq 146
Cdd:NF033858 337 TRRrvgymsqafslygeLTVRQ--NL---ELhARLFHLP----------AAEIAARV--AEMLERFD--------LADV- 390

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 550714244 147 ipaaemrLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALD 192
Cdd:NF033858 391 -------ADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429

GguA

NF040905

sugar ABC transporter ATP-binding protein;

6-248

7.07e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 7.07e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   6 FKDSTP-----VLRLQNLNVkfaGSPVS----VLEDISLAVRAGETLALVGESGCGKsiTSLAlMGLLPAS-ARIVSGE- 74
Cdd:NF040905 246 YPERTPkigevVFEVKNWTV---YHPLHperkVVDDVSLNVRRGEIVGIAGLMGAGR--TELA-MSVFGRSyGRNISGTv 319

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  75 -MHFRRHDLRklSPRE-------YANLRGSELAMIFQEPMTSLNPAFTLGdqlseAVMRHQTLSRAEAMTVALQILEKVQ 146
Cdd:NF040905 320 fKDGKEVDVS--TVSDaidaglaYVTEDRKGYGLNLIDDIKRNITLANLG-----KVSRRGVIDENEEIKVAEEYRKKMN 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 147 IPAAEMRLKVypHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAE 226
Cdd:NF040905 393 IKTPSVFQKV--GNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLG 469

                        250       260
                 ....*....|....*....|....*..
gi 550714244 227 VAQQVAVMYAGQVV-----EQGSVEAI 248
Cdd:NF040905 470 MCDRIYVMNEGRITgelprEEASQERI 496

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

160-235

1.03e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 53.25 E-value: 1.03e-07

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTiqaQILALLNTLKE--ETGTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:COG1245  212 ELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIY---QRLNVARLIRElaEEGKYVLVVEHDLAILDYLADYVHILY 286

PLN03130

ABC transporter C family member; Provisional

29-251

1.03e-07

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 53.59 E-value: 1.03e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSitslalmGLLPASARIV---SGEMHFRRHDLRKLSpreYANLRgSELAMIFQEP 105
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKS-------SMLNALFRIVeleRGRILIDGCDISKFG---LMDLR-KVLGIIPQAP 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  106 MT-------SLNPAFTLGD-QLSEAVMR-H-QTLSRAEAMTVALQILEkvqipAAEmrlkvyphQLSGGMRQRVMIAMAL 175
Cdd:PLN03130 1323 VLfsgtvrfNLDPFNEHNDaDLWESLERaHlKDVIRRNSLGLDAEVSE-----AGE--------NFSVGQRQLLSLARAL 1389

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244  176 INHPKLLIADEPTTALDVTIQAQIlalLNTLKEETGT-AVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PLN03130 1390 LRRSKILVLDEATAAVDVRTDALI---QKTIREEFKScTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSN 1462

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

11-244

1.47e-07

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 53.09 E-value: 1.47e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    11 PVLRLQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRklsprey 90
Cdd:TIGR01257  927 PGVCVKNLVKIFEPSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPT----SGTVLVGGKDIE------- 995

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    91 anlrgSELAMIFQepmtslnpafTLGDQLSEAVMRHQtLSRAEAMTVALQI----LEKVQIPAAEMRLKVYPHQ------ 160
Cdd:TIGR01257  996 -----TNLDAVRQ----------SLGMCPQHNILFHH-LTVAEHILFYAQLkgrsWEEAQLEMEAMLEDTGLHHkrneea 1059

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   161 --LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLntLKEETGTAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:TIGR01257 1060 qdLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGR 1137


                   ....*.
gi 550714244   239 VVEQGS 244
Cdd:TIGR01257 1138 LYCSGT 1143

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

152-247

2.00e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 52.42 E-value: 2.00e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 152 MRLKVYPHQ-----LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAE 226
Cdd:PRK10982 378 MRVKTPGHRtqigsLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLG 456

                         90       100
                 ....*....|....*....|.
gi 550714244 227 VAQQVAVMYAGQVVeqGSVEA 247
Cdd:PRK10982 457 ITDRILVMSNGLVA--GIVDT 475

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

29-220

2.82e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 51.86 E-value: 2.82e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSiTSLALMgllpasARI---VSGEMhfrrhdlrKLSPreyanlrGSELAMIFQEP 105
Cdd:TIGR03719  20 ILKDISLSFFPGAKIGVLGLNGAGKS-TLLRIM------AGVdkdFNGEA--------RPQP-------GIKVGYLPQEP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  106 mtSLNPAFTLGDQLSEAVMR-HQTLSRAEAMTVA-----------------LQ-ILE---------KVQIPAAEMRL--- 154
Cdd:TIGR03719  78 --QLDPTKTVRENVEEGVAEiKDALDRFNEISAKyaepdadfdklaaeqaeLQeIIDaadawdldsQLEIAMDALRCppw 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550714244  155 --KVypHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDvtiqAQILALL-NTLKEETGTaVLMITHD 220
Cdd:TIGR03719 156 daDV--TKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD----AESVAWLeRHLQEYPGT-VVAVTHD 217

PTZ00265

multidrug resistance protein (mdr1); Provisional

157-224

4.00e-07

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 51.95 E-value: 4.00e-07

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244  157 YPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVV 224
Cdd:PTZ00265 1355 YGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASI 1422

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

19-200

7.58e-07

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 51.06 E-value: 7.58e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    19 NVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMG-LLPASARIvsgemhfrRHDLRklspreyanlrgse 97
Cdd:TIGR01271  433 NFSLYVTPV--LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGeLEPSEGKI--------KHSGR-------------- 488

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    98 lamIFQEPMTSLNPAFTLGDQ----LSEAVMRHQTLSRAEAMTVALQIL-EKVQIPAAEMRLkvyphQLSGGMRQRVMIA 172
Cdd:TIGR01271  489 ---ISFSPQTSWIMPGTIKDNiifgLSYDEYRYTSVIKACQLEEDIALFpEKDKTVLGEGGI-----TLSGGQRARISLA 560

                          170       180
                   ....*....|....*....|....*...
gi 550714244   173 MALINHPKLLIADEPTTALDVTIQAQIL 200
Cdd:TIGR01271  561 RAVYKDADLYLLDSPFTHLDVVTEKEIF 588

PRK11147

ABC transporter ATPase component; Reviewed

13-240

9.73e-07

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 50.33 E-value: 9.73e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEMHFRRhDLR--KLS---P 87
Cdd:PRK11147   4 ISIHGAWLSFSDAPL--LDNAELHIEDNERVCLVGRNGAGKS----TLMKILNGEVLLDDGRIIYEQ-DLIvaRLQqdpP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  88 ReyaNLRGS----------ELA-----------MIFQEPMTS-LNpaftlgdQLSE--AVMRHQTLSRAEAMTValQILE 143
Cdd:PRK11147  77 R---NVEGTvydfvaegieEQAeylkryhdishLVETDPSEKnLN-------ELAKlqEQLDHHNLWQLENRIN--EVLA 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 144 KVQIPAaEMRLKvyphQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTiqaQILALLNTLKEETGTAVLmITHDLGV 223
Cdd:PRK11147 145 QLGLDP-DAALS----SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIE---TIEWLEGFLKTFQGSIIF-ISHDRSF 215

                        250
                 ....*....|....*..
gi 550714244 224 VAEVAQQVAVMYAGQVV 240
Cdd:PRK11147 216 IRNMATRIVDLDRGKLV 232

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

27-244

1.10e-06

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 50.49 E-value: 1.10e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    27 VSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSPReyanLRG-----SELAMI 101
Cdd:TIGR00956   74 FDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHIGVEGVITYDGITPEEIKKH----YRGdvvynAETDVH 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   102 FqepmtslnPAFTLGDQLsEAVMRHQT----------LSRAEAMT-VALQIL-------EKVqipAAEMRLKVyphqlSG 163
Cdd:TIGR00956  150 F--------PHLTVGETL-DFAARCKTpqnrpdgvsrEEYAKHIAdVYMATYglshtrnTKV---GNDFVRGV-----SG 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   164 GMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVA-EVAQQVAVMYAGQVVEQ 242
Cdd:TIGR00956  213 GERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQDAyELFDKVIVLYEGYQIYF 292


                   ..
gi 550714244   243 GS 244
Cdd:TIGR00956  293 GP 294

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

161-221

1.24e-06

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 49.78 E-value: 1.24e-06

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDL 221
Cdd:COG1245  456 LSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDI 516

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

15-254

1.52e-06

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 49.91 E-value: 1.52e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    15 LQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRRHDLRKLSpreyanlr 94
Cdd:TIGR01271 1220 VQGLTAKYTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTEGEIQIDGVSWNSVTLQTWR-------- 1291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    95 gSELAMIFQEpmtslnpAFTLGDQLSEAVMRHQTLSRAEAMTVALQI-LEKV--QIPAA-EMRLKVYPHQLSGGMRQRVM 170
Cdd:TIGR01271 1292 -KAFGVIPQK-------VFIFSGTFRKNLDPYEQWSDEEIWKVAEEVgLKSVieQFPDKlDFVLVDGGYVLSNGHKQLMC 1363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   171 IAMALINHPKLLIADEPTTALD-VTIQaqilALLNTLKEE-TGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSVEAI 248
Cdd:TIGR01271 1364 LARSILSKAKILLLDEPSAHLDpVTLQ----IIRKTLKQSfSNCTVILSEHRVEALLE-CQQFLVIEGSSVKQYDSIQKL 1438


                   ....*.
gi 550714244   249 FADPQH 254
Cdd:TIGR01271 1439 LNETSL 1444

ABC_UvrA_II

cd03271

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...

15-225

1.81e-06

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 48.38 E-value: 1.81e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFagsPVSVLEDISlavragetlalvGESGCGKSitSLALMGLLPASARivsgemhfrRHDLRKLSPREYANLR 94
Cdd:cd03271   11 LKNIDVDI---PLGVLTCVT------------GVSGSGKS--SLINDTLYPALAR---------RLHLKKEQPGNHDRIE 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 GSE----LAMIFQEPM---TSLNPA-----FTL--------------GDQLSEAVMRHQTLSRAEAMTV--ALQILEKvq 146
Cdd:cd03271   65 GLEhidkVIVIDQSPIgrtPRSNPAtytgvFDEirelfcevckgkryNRETLEVRYKGKSIADVLDMTVeeALEFFEN-- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 147 IPAAEMRLKV-------YPH------QLSGGMRQRVMIAMALIN---HPKLLIADEPTTAL---DVtiqAQILALLNTLK 207
Cdd:cd03271  143 IPKIARKLQTlcdvglgYIKlgqpatTLSGGEAQRIKLAKELSKrstGKTLYILDEPTTGLhfhDV---KKLLEVLQRLV 219

                        250
                 ....*....|....*...
gi 550714244 208 EEtGTAVLMITHDLGVVA 225
Cdd:cd03271  220 DK-GNTVVVIEHNLDVIK 236

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

161-221

1.84e-06

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 49.42 E-value: 1.84e-06

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDL 221
Cdd:PRK13409 454 LSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDI 514

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

160-220

1.92e-06

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 49.16 E-value: 1.92e-06

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244  160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDV-TIQaqilALLNTLKEETGTAVLmITHD 220
Cdd:TIGR03719 443 QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVeTLR----ALEEALLNFAGCAVV-ISHD 499

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

161-220

2.16e-06

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 49.35 E-value: 2.16e-06

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDvtiqAQILALL-NTLKEETGTaVLMITHD 220
Cdd:PRK11819 164 LSGGERRRVALCRLLLEKPDMLLLDEPTNHLD----AESVAWLeQFLHDYPGT-VVAVTHD 219

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

40-226

2.19e-06

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 46.60 E-value: 2.19e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    40 GETLALVGESGCGKSITSLALMGLLPASAR---IVSGEMHFRRHDLRKLspreyanlrgselamifqepmtslnpaftlg 116
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGgviYIDGEDILEEVLDQLL------------------------------- 50

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   117 dqlseavmrhqtlsraeamtvalqilekvqipaaEMRLKVYPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQ 196
Cdd:smart00382  51 ----------------------------------LIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQE 96

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 550714244   197 AQILALLNT-----LKEETGTAVLMITHDLGVVAE 226
Cdd:smart00382  97 ALLLLLEELrllllLKSEKNLTVILTTNDEKDLGP 131

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

15-254

2.77e-06

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 47.93 E-value: 2.77e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPasariVSGEMHFRRHDLRKLSPREYANLR 94
Cdd:cd03289    5 VKDLTAKYTEGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-----TEGDIQIDGVSWNSVPLQKWRKAF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 G--SELAMIFQEPM-TSLNPAFTLGDQlseavmrhqtlsraEAMTVALQI-LEKV--QIPAA-EMRLKVYPHQLSGGMRQ 167
Cdd:cd03289   80 GviPQKVFIFSGTFrKNLDPYGKWSDE--------------EIWKVAEEVgLKSVieQFPGQlDFVLVDGGCVLSHGHKQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALD-VTIQaqilALLNTLKEE-TGTAVLMITHDLGVVAEvAQQVAVMYAGQVVEQGSV 245
Cdd:cd03289  146 LMCLARSVLSKAKILLLDEPSAHLDpITYQ----VIRKTLKQAfADCTVILSEHRIEAMLE-CQRFLVIEENKVRQYDSI 220


                 ....*....
gi 550714244 246 EAIFADPQH 254
Cdd:cd03289  221 QKLLNEKSH 229

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

161-248

2.94e-06

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.86 E-value: 2.94e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  161 LSGGMRQRVMIAMAL---INHPKLLIADEPTTAL---DVtiqAQILALLNTLKEEtGTAVLMITHDLGVVaEVAQQVAVM 234
Cdd:TIGR00630 830 LSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLhfdDI---KKLLEVLQRLVDK-GNTVVVIEHNLDVI-KTADYIIDL 904

                          90       100
                  ....*....|....*....|
gi 550714244  235 ------YAGQVVEQGSVEAI 248
Cdd:TIGR00630 905 gpeggdGGGTVVASGTPEEV 924

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

160-235

3.21e-06

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 48.65 E-value: 3.21e-06

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTiqaQILALLNTLKEET-GTAVLMITHDLGVVAEVAQQVAVMY 235
Cdd:PRK13409 212 ELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIR---QRLNVARLIRELAeGKYVLVVEHDLAVLDYLADNVHIAY 285

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

161-243

4.45e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 46.55 E-value: 4.45e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIA--MALINHPKLLIADEPTTALDvtiQAQILALLNTLKE--ETGTAVLMITHDLGVVAEVAQQVAV--- 233
Cdd:cd03238   88 LSGGELQRVKLAseLFSEPPGTLFILDEPSTGLH---QQDINQLLEVIKGliDLGNTVILIEHNLDVLSSADWIIDFgpg 164

                         90
                 ....*....|..
gi 550714244 234 --MYAGQVVEQG 243
Cdd:cd03238  165 sgKSGGKVVFSG 176

ABCG_PDR_domain2

cd03232

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...

11-219

5.78e-06

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 46.08 E-value: 5.78e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  11 PVLRLQNLN--VKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLpaSAR----IVSGEMHfrrhdlrk 84
Cdd:cd03232    2 SVLTWKNLNytVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKT----TLLDVL--AGRktagVITGEIL-------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  85 lspreyanLRGSELAMIFQ------EPMTSLNPAFTlgdqLSEAVMRHQTLsRAeamtvalqilekvqipaaemrlkvyp 158
Cdd:cd03232   68 --------INGRPLDKNFQrstgyvEQQDVHSPNLT----VREALRFSALL-RG-------------------------- 108

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 159 hqLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKeETGTAVLMITH 219
Cdd:cd03232  109 --LSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLA-DSGQAILCTIH 166

PLN03073

ABC transporter F family; Provisional

13-193

6.08e-06

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 47.93 E-value: 6.08e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVSVLEDISLAVraGETLALVGESGCGKSiTSLALMGL-----LPASARIVSGEMHFRRHDLRKL-- 85
Cdd:PLN03073 178 IHMENFSISVGGRDLIVDASVTLAF--GRHYGLVGRNGTGKT-TFLRYMAMhaidgIPKNCQILHVEQEVVGDDTTALqc 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  86 ---SPREYANLRGSELAMIFQEPMTSLNPAF--------------TLGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIp 148
Cdd:PLN03073 255 vlnTDIERTQLLEEEAQLVAQQRELEFETETgkgkgankdgvdkdAVSQRLEEIYKRLELIDAYTAEARAASILAGLSF- 333

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 550714244 149 AAEMRLKVyPHQLSGGMRQRVMIAMALINHPKLLIADEPTTALDV 193
Cdd:PLN03073 334 TPEMQVKA-TKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

30-251

6.48e-06

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 46.73 E-value: 6.48e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHfrrhdlrklspreyanlRGSELAMIFQEpmTSL 109
Cdd:PRK13546  40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPT----VGKVD-----------------RNGEVSVIAIS--AGL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 110 NPAFTlGDQLSEAVMRHQTLSRAEAMTVALQILEkvqipAAEMRLKVYP--HQLSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:PRK13546  97 SGQLT-GIENIEFKMLCMGFKRKEIKAMTPKIIE-----FSELGEFIYQpvKKYSSGMRAKLGFSINITVNPDILVIDEA 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550714244 188 TTALDVTIQAQILALLNTLKEETGTaVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAIFAD 251
Cdd:PRK13546 171 LSVGDQTFAQKCLDKIYEFKEQNKT-IFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPK 233

ABCC_CFTR1

cd03291

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...

19-199

8.27e-06

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 46.77 E-value: 8.27e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  19 NVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIV--SGEMHFrrhdlrklspreyanlrGS 96
Cdd:cd03291   44 NLCLVGAPV--LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIkhSGRISF-----------------SS 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  97 ELAMIFqePMTsLNPAFTLGdqLSEAVMRHQTLSRAEAMTVALQIL-EKVQIPAAEMRLkvyphQLSGGMRQRVMIAMAL 175
Cdd:cd03291  105 QFSWIM--PGT-IKENIIFG--VSYDEYRYKSVVKACQLEEDITKFpEKDNTVLGEGGI-----TLSGGQRARISLARAV 174

                        170       180
                 ....*....|....*....|....
gi 550714244 176 INHPKLLIADEPTTALDVTIQAQI 199
Cdd:cd03291  175 YKDADLYLLDSPFGYLDVFTEKEI 198

PLN03232

ABC transporter C family member; Provisional

5-249

9.43e-06

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 47.66 E-value: 9.43e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    5 PFKDSTPVLRLQNLNVKF-AGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGllpasarivsgemhfrrhdlr 83
Cdd:PLN03232  607 PLQPGAPAISIKNGYFSWdSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLG--------------------- 665

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   84 KLSPREYAN--LRGSeLAMIFQEPMtslnpaftlgdqLSEAVMRHQTL--SRAEAMtvalQILEKVQIPAAEMRLKVYPH 159
Cdd:PLN03232  666 ELSHAETSSvvIRGS-VAYVPQVSW------------IFNATVRENILfgSDFESE----RYWRAIDVTALQHDLDLLPG 728

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  160 Q-----------LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILAllNTLKEE-TGTAVLMITHDLGVVAEV 227
Cdd:PLN03232  729 RdlteigergvnISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFD--SCMKDElKGKTRVLVTNQLHFLPLM 806

                         250       260
                  ....*....|....*....|..
gi 550714244  228 aQQVAVMYAGQVVEQGSVEAIF 249
Cdd:PLN03232  807 -DRIILVSEGMIKEEGTFAELS 827

ABC_Class2

cd03227

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...

131-231

1.26e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.

Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 44.66 E-value: 1.26e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 131 RAEAMTVALQILEKVQIPAAEMRLKVYPHQLSGGMRQRVMIAMALINHPK----LLIADEPTTALDVTIQAqilALLNTL 206
Cdd:cd03227   48 AQSATRRRSGVKAGCIVAAVSAELIFTRLQLSGGEKELSALALILALASLkprpLYILDEIDRGLDPRDGQ---ALAEAI 124

                         90       100
                 ....*....|....*....|....*..
gi 550714244 207 KEET--GTAVLMITHDLGVVAEVAQQV 231
Cdd:cd03227  125 LEHLvkGAQVIVITHLPELAELADKLI 151

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

15-251

1.58e-05

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 46.26 E-value: 1.58e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  15 LQNLNVKFAGspVSVLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASarivSGEMHFRRHDLRKLSPREYANlr 94
Cdd:PRK10982   1 MSNISKSFPG--VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKD----SGSILFQGKEIDFKSSKEALE-- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  95 gSELAMIFQEpmtslnpaftLGDQLSEAVMRHQTLSR--AEAMTV-ALQILEKVQIPAAEMRLKVYPHQ----LSGGMRQ 167
Cdd:PRK10982  73 -NGISMVHQE----------LNLVLQRSVMDNMWLGRypTKGMFVdQDKMYRDTKAIFDELDIDIDPRAkvatLSVSQMQ 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 168 RVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEA 247
Cdd:PRK10982 142 MIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAG 220


                 ....
gi 550714244 248 IFAD 251
Cdd:PRK10982 221 LTMD 224

PRK10636

putative ABC transporter ATP-binding protein; Provisional

29-220

1.60e-05

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 46.70 E-value: 1.60e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  29 VLEDISLAVRAGETLALVGESGCGKSiTSLALM-GLLPASArivsGEMHFrrhdlrklsPREYAnlrgseLAMIFQEPMT 107
Cdd:PRK10636  16 LLDNATATINPGQKVGLVGKNGCGKS-TLLALLkNEISADG----GSYTF---------PGNWQ------LAWVNQETPA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 108 SLNPAFTL---GD--------QLSEAVMR---------HQTLSRAEAMTV---ALQILEKVQIPAAEMRLKVypHQLSGG 164
Cdd:PRK10636  76 LPQPALEYvidGDreyrqleaQLHDANERndghaiatiHGKLDAIDAWTIrsrAASLLHGLGFSNEQLERPV--SDFSGG 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 165 MRQRVMIAMALINHPKLLIADEPTTALDVTiqaQILALLNTLKEETGTAVLmITHD 220
Cdd:PRK10636 154 WRMRLNLAQALICRSDLLLLDEPTNHLDLD---AVIWLEKWLKSYQGTLIL-ISHD 205

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

160-220

1.77e-05

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 46.27 E-value: 1.77e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550714244 160 QLSGGMRQRVMIAMALINHPKLLIADEPTTALDV-TIQaqilALLNTLKEETGTAVLmITHD 220
Cdd:PRK11819 445 VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVeTLR----ALEEALLEFPGCAVV-ISHD 501

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

159-219

8.53e-05

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 44.24 E-value: 8.53e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITH 219
Cdd:PRK10938 400 HSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSH 460

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

30-243

1.04e-04

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 43.17 E-value: 1.04e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAG-----ETLALVGESGCGKSITSLALMGLLPASArivsGEMhfrrhdlrklspreyanlrGSELAMIFQE 104
Cdd:cd03237   10 LGEFTLEVEGGsisesEVIGILGPNGIGKTTFIKMLAGVLKPDE----GDI-------------------EIELDTVSYK 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 105 PMTsLNPAF--TLGDQLSEAVMRHQTLS--RAEAMTvALQIlEKV---QIPaaemrlkvyphQLSGGMRQRVMIAMALIN 177
Cdd:cd03237   67 PQY-IKADYegTVRDLLSSITKDFYTHPyfKTEIAK-PLQI-EQIldrEVP-----------ELSGGELQRVAIAACLSK 132

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714244 178 HPKLLIADEPTTALDVTIQAQILALLNTLKEETGTAVLMITHDLGVVAEVAQQVAVmYAGQVVEQG 243
Cdd:cd03237  133 DADIYLLDEPSAYLDVEQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV-FEGEPSVNG 197

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

30-248

1.65e-04

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 43.34 E-value: 1.65e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETLALVGESGCGKSITSLALMGL-LPASARIvsgemhfrrhdlrklspreyaNLRGSELAMIFQepmTS 108
Cdd:PRK13545  40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVtMPNKGTV---------------------DIKGSAALIAIS---SG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 109 LNPAFTlGDQLSEAVMRHQTLSRAEAMTVALQILEKVQIPA-AEMRLKVYphqlSGGMRQRVMIAMALINHPKLLIADEP 187
Cdd:PRK13545  96 LNGQLT-GIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKfIYQPVKTY----SSGMKSRLGFAISVHINPDILVIDEA 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550714244 188 TTALDVTIQAQILALLNTLKEEtGTAVLMITHDLGVVAEVAQQVAVMYAGQVVEQGSVEAI 248
Cdd:PRK13545 171 LSVGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230

PLN03130

ABC transporter C family member; Provisional

161-251

1.76e-04

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 43.57 E-value: 1.76e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  161 LSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAQILAllNTLKEETG--TAVLmITHDLGVVAEVaQQVAVMYAGQ 238
Cdd:PLN03130  741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFD--KCIKDELRgkTRVL-VTNQLHFLSQV-DRIILVHEGM 816

                          90
                  ....*....|...
gi 550714244  239 VVEQGSVEAIFAD 251
Cdd:PLN03130  817 IKEEGTYEELSNN 829

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

16-219

2.01e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 43.17 E-value: 2.01e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    16 QNLN--VKFAGSPVSVLEDISLAVRAGETLALVGESGCGKSITSLAL-----MGLLPASARIVSGemhfrrHDLRKLSPR 88
Cdd:TIGR00956  763 RNLTyeVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLaervtTGVITGGDRLVNG------RPLDSSFQR 836

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244    89 EYANLRGSELAMifqePMTSLNPAFtlgdQLSEAVMRHQTLSRAEAMTVALQILEKVQIPA-AEMRLKVYPHQLSGGMRQ 167
Cdd:TIGR00956  837 SIGYVQQQDLHL----PTSTVRESL----RFSAYLRQPKSVSKSEKMEYVEEVIKLLEMESyADAVVGVPGEGLNVEQRK 908

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 550714244   168 RVMIAMALINHPKLLI-ADEPTTALDVTIQAQILALLNTLKeETGTAVLMITH 219
Cdd:TIGR00956  909 RLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIH 960

PRK00635

excinuclease ABC subunit A; Provisional

161-224

2.77e-04

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.89 E-value: 2.77e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714244  161 LSGGMRQRVMIAMALIN---HPKLLIADEPTTALDV-TIQAQILALLNTLKEetGTAVLMITHDLGVV 224
Cdd:PRK00635  810 LSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHThDIKALIYVLQSLTHQ--GHTVVIIEHNMHVV 875

PRK15064

ABC transporter ATP-binding protein; Provisional

13-246

3.54e-04

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 42.19 E-value: 3.54e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  13 LRLQNLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVsgemhfrrhdlrklspreyan 92
Cdd:PRK15064 320 LEVENLTKGFDNGPL--FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV--------------------- 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  93 lRGSELAMI----------FQEPMtslnpafTLGDQLS--------EAVMRhQTLSRaeAMTVALQILEKVQIpaaemrl 154
Cdd:PRK15064 377 -KWSENANIgyyaqdhaydFENDL-------TLFDWMSqwrqegddEQAVR-GTLGR--LLFSQDDIKKSVKV------- 438

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 155 kvyphqLSGGMRQRVMIAMALINHPKLLIADEPTTALDVtiqAQILALLNTLKEETGTaVLMITHDLGVVAEVAQQVAVM 234
Cdd:PRK15064 439 ------LSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDM---ESIESLNMALEKYEGT-LIFVSHDREFVSSLATRIIEI 508

                        250
                 ....*....|...
gi 550714244 235 YAGQVVE-QGSVE 246
Cdd:PRK15064 509 TPDGVVDfSGTYE 521

PLN03140

ABC transporter G family member; Provisional

29-243

4.41e-04

ABC transporter G family member; Provisional

Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 42.14 E-value: 4.41e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244   29 VLEDISLAVRAGETLALVGESGCGKSitslALMGLLpaSARIVSGemhFRRHDLRkLS--PRE---YANLRGselamiFQ 103
Cdd:PLN03140  895 LLREVTGAFRPGVLTALMGVSGAGKT----TLMDVL--AGRKTGG---YIEGDIR-ISgfPKKqetFARISG------YC 958

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  104 EPMTSLNPAFTLGDQL-SEAVMR-HQTLSRAEAMTVALQILEKVQIPAAEMRLKVYP--HQLSGGMRQRVMIAMALINHP 179
Cdd:PLN03140  959 EQNDIHSPQVTVRESLiYSAFLRlPKEVSKEEKMMFVDEVMELVELDNLKDAIVGLPgvTGLSTEQRKRLTIAVELVANP 1038

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244  180 KLLIADEPTTALDVTIQAQIL-ALLNTLkeETGTAVLMITHDLGV-VAEVAQQVAVM-YAGQVVEQG 243
Cdd:PLN03140 1039 SIIFMDEPTSGLDARAAAIVMrTVRNTV--DTGRTVVCTIHQPSIdIFEAFDELLLMkRGGQVIYSG 1103

ABC_Rad50

cd03240

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...

44-220

4.89e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.

Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 40.67 E-value: 4.89e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  44 ALVGESGCGKSIT----SLALMGLLPASARIVsgemHFRRHDLRKLSPREYANLRGSELAmifQEPMT---SLNpaftlg 116
Cdd:cd03240   26 LIVGQNGAGKTTIiealKYALTGELPPNSKGG----AHDPKLIREGEVRAQVKLAFENAN---GKKYTitrSLA------ 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 117 dQLSEAVMRHQtlsraeamtvalqilEKVQIPAAEMRlkvypHQLSGGMRQ------RVMIAMALINHPKLLIADEPTTA 190
Cdd:cd03240   93 -ILENVIFCHQ---------------GESNWPLLDMR-----GRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTN 151

                        170       180       190
                 ....*....|....*....|....*....|.
gi 550714244 191 LDV-TIQAQILALLNTLKEETGTAVLMITHD 220
Cdd:cd03240  152 LDEeNIEESLAEIIEERKSQKNFQLIVITHD 182

YbjD

COG3593

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...

30-219

1.39e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];

Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 39.99 E-value: 1.39e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  30 LEDISLAVRAGETlALVGESGCGKSitSL--ALMGLLPASARIvsgemHFRRHD---------------------LRKLS 86
Cdd:COG3593   14 IKDLSIELSDDLT-VLVGENNSGKS--SIleALRLLLGPSSSR-----KFDEEDfylgddpdlpeieieltfgslLSRLL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  87 PREYANLRGSELAMIFQEPMTSLNPAF-TLGDQLSEAV---MRHQTLSRAEAMTVALQILEKVQIPAAEmRLKVYPHQLS 162
Cdd:COG3593   86 RLLLKEEDKEELEEALEELNEELKEALkALNELLSEYLkelLDGLDLELELSLDELEDLLKSLSLRIED-GKELPLDRLG 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550714244 163 GGMRQRVMIAMALI-------NHPKLLIADEPTTALDVTIQAQILALLNTLKEETGTaVLMITH 219
Cdd:COG3593  165 SGFQRLILLALLSAlaelkraPANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQ-VIITTH 227

PRK01156

chromosome segregation protein; Provisional

161-231

1.59e-03

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 40.27 E-value: 1.59e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQ------RVMIAMALINHPKLLIADEPTTALDVTIQAQILALLN-TLKEETGT-AVLMITH--DLGVVAEVAQQ 230
Cdd:PRK01156 802 LSGGEKTavafalRVAVAQFLNNDKSLLIMDEPTAFLDEDRRTNLKDIIEySLKDSSDIpQVIMISHhrELLSVADVAYE 881


                 .
gi 550714244 231 V 231
Cdd:PRK01156 882 V 882

UvrA

COG0178

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

161-224

1.65e-03

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 40.39 E-value: 1.65e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 161 LSGGMRQRVMIAMALI---NHPKLLIADEPTTAL---DVtiqAQILALLNTLKEEtGTAVLMITHDLGVV 224
Cdd:COG0178  827 LSGGEAQRVKLASELSkrsTGKTLYILDEPTTGLhfhDI---RKLLEVLHRLVDK-GNTVVVIEHNLDVI 892

PLN03073

ABC transporter F family; Provisional

159-239

1.80e-03

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 40.23 E-value: 1.80e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 159 HQLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTiqaQILALLNTLKEETGtAVLMITHDLGVVAEVAQQVAVMYAGQ 238
Cdd:PLN03073 626 YTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLD---AVEALIQGLVLFQG-GVLMVSHDEHLISGSVDELWVVSEGK 701


                 .
gi 550714244 239 V 239
Cdd:PLN03073 702 V 702

PRK10636

putative ABC transporter ATP-binding protein; Provisional

10-239

1.90e-03

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 40.15 E-value: 1.90e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  10 TPVLRLQNLNVKFAGSpvSVLEDISLAVRAGETLALVGESGCGKSitslALMGLLPASARIVSGEM---------HFRRH 80
Cdd:PRK10636 310 NPLLKMEKVSAGYGDR--IILDSIKLNLVPGSRIGLLGRNGAGKS----TLIKLLAGELAPVSGEIglakgiklgYFAQH 383

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  81 DLRKLSPREYANLRGSELAMifQEPMTSLNP---AFTL-GDQLSEAVMRhqtlsraeamtvalqilekvqipaaemrlkv 156
Cdd:PRK10636 384 QLEFLRADESPLQHLARLAP--QELEQKLRDylgGFGFqGDKVTEETRR------------------------------- 430

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244 157 yphqLSGGMRQRVMIAMALINHPKLLIADEPTTALDVTIQAqilALLNTLKEETGtAVLMITHDLGVVAEVAQQVAVMYA 236
Cdd:PRK10636 431 ----FSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQ---ALTEALIDFEG-ALVVVSHDRHLLRSTTDDLYLVHD 502


                 ...
gi 550714244 237 GQV 239
Cdd:PRK10636 503 GKV 505

PRK15064

ABC transporter ATP-binding protein; Provisional

17-220

4.18e-03

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 38.72 E-value: 4.18e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  17 NLNVKFAGSPVsvLEDISLAVRAGETLALVGESGCGKSITSLALMGLLPASARIVSGEMHFRrhdLRKLSPREYAnlrgs 96
Cdd:PRK15064   6 NITMQFGAKPL--FENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNER---LGKLRQDQFA----- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714244  97 elamiFQEpMTSLNpAFTLGDQLSEAVM--RHQTLSRAEA-----MTVA-LQ-----------------ILEKVQIPAae 151
Cdd:PRK15064  76 -----FEE-FTVLD-TVIMGHTELWEVKqeRDRIYALPEMseedgMKVAdLEvkfaemdgytaearageLLLGVGIPE-- 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 550714244 152 mrlkvypHQLSGGMRQ-------RVMIAMALINHPKLLIADEPTTALDV-TIQaqilALLNTLKEETGTAVLmITHD 220
Cdd:PRK15064 147 -------EQHYGLMSEvapgwklRVLLAQALFSNPDILLLDEPTNNLDInTIR----WLEDVLNERNSTMII-ISHD 211

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01