|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
7-316 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 560.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 7 KKLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRAS 86
Cdd:COG0462 2 KDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 87 ARHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKME 166
Cdd:COG0462 82 ARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKDLE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 167 DLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKS 246
Cdd:COG0462 162 DLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGAKS 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 247 VMACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:COG0462 242 VYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEKRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
9-316 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 557.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 9 LKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASAR 88
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 89 HITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKMEDL 168
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNLENL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 169 IVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVM 248
Cdd:PRK01259 161 VVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVY 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 546349052 249 ACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHK-LPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:PRK01259 241 AYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKkCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
9-316 |
1.25e-152 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 429.78 E-value: 1.25e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 9 LKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIV-QPTSYPVNDNLIELLVMADALKRASA 87
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 88 RHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKMED 167
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILDN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 168 LIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQP-GVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKS 246
Cdd:TIGR01251 161 PVVVSPDAGGVERAKKVADALGCPLAIIDKRRISAtNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKR 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 247 VMACVTHAVLTDPACERIENSNIKELIVTNTIdlPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:TIGR01251 241 VIAAATHGVFSGPAIERIANAGVEEVIVTNTI--PHEKHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
9-125 |
4.02e-77 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 231.15 E-value: 4.02e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 9 LKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASAR 88
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 546349052 89 HITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAG 125
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
153-277 |
1.54e-28 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 106.71 E-value: 1.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 153 ASILAKYINEKKMEDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPG------VAKVMNLIGNVEGKNCIIIDDIV 226
Cdd:cd06223 2 GRLLAEEIREDLLEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGrtpsepYGLELPLGGDVKGKRVLLVDDVI 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 546349052 227 DTAGSLVEGAKALKEFGAKSVMACVTHAVLTDpaCERIENSNIKELIVTNT 277
Cdd:cd06223 82 ATGGTLLAAIELLKEAGAKVVGVAVLLDKPEG--GARELASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
7-316 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 560.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 7 KKLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRAS 86
Cdd:COG0462 2 KDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 87 ARHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKME 166
Cdd:COG0462 82 ARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKDLE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 167 DLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKS 246
Cdd:COG0462 162 DLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGAKS 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 247 VMACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:COG0462 242 VYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEKRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
9-316 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 557.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 9 LKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASAR 88
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 89 HITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKMEDL 168
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNLENL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 169 IVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVM 248
Cdd:PRK01259 161 VVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVY 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 546349052 249 ACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHK-LPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:PRK01259 241 AYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKkCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
9-316 |
1.25e-152 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 429.78 E-value: 1.25e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 9 LKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIV-QPTSYPVNDNLIELLVMADALKRASA 87
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 88 RHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKMED 167
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILDN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 168 LIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQP-GVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKS 246
Cdd:TIGR01251 161 PVVVSPDAGGVERAKKVADALGCPLAIIDKRRISAtNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKR 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 247 VMACVTHAVLTDPACERIENSNIKELIVTNTIdlPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:TIGR01251 241 VIAAATHGVFSGPAIERIANAGVEEVIVTNTI--PHEKHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
5-315 |
2.44e-146 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 414.91 E-value: 2.44e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 5 DGKKLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKR 84
Cdd:PRK02812 18 DNNRLRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 85 ASARHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKK 164
Cdd:PRK02812 98 ASARQITAVIPYYGYARADRKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASKN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 165 MEDLIVVSPDLGGVTRARDLADRI-GAPIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFG 243
Cdd:PRK02812 178 LEDIVVVSPDVGGVARARAFAKKLnDAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKEG 257
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 546349052 244 AKSVMACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLF 315
Cdd:PRK02812 258 AKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVPEERRFPQLKVLSVANMLGEAIWRIHEESSVSSMF 329
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
8-316 |
7.67e-144 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 408.03 E-value: 7.67e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 8 KLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASA 87
Cdd:PRK02269 5 DLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 88 RHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKM-- 165
Cdd:PRK02269 85 ESINVVMPYYGYARQDRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLvg 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 166 EDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRP--QPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFG 243
Cdd:PRK02269 165 DDVVVVSPDHGGVTRARKLAQFLKTPIAIIDKRRSvdKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADALAEAG 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 546349052 244 AKSVMACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:PRK02269 245 ATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEERLIDKIEQISIADLLGEAIIRIHEKRPLSPLFE 317
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
18-316 |
9.75e-141 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 399.45 E-value: 9.75e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 18 PELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASARHITAVVPYY 97
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 98 GYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKKM--EDLIVVSPDL 175
Cdd:PLN02369 81 GYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTIssPDLVVVSPDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 176 GGVTRARDLADRIG-APIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMACVTHA 254
Cdd:PLN02369 161 GGVARARAFAKKLSdAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 546349052 255 VLTDPACERIENSNIKELIVTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:PLN02369 241 VFSPPAIERLSSGLFQEVIVTNTIPVSEKNYFPQLTVLSVANLLGETIWRVHDDCSVSSIFD 302
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
20-316 |
1.05e-132 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 379.29 E-value: 1.05e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 20 LAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASARHITAVVPYYGY 99
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 100 ARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEK-KMEDLIVVSPDLGGV 178
Cdd:PRK03092 81 ARQDKKHRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKyDLDNVTVVSPDAGRV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 179 TRARDLADRIG-APIAIIEKKRP--QPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMACVTHAV 255
Cdd:PRK03092 161 RVAEQWADRLGgAPLAFIHKTRDptVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHGV 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 546349052 256 LTDPACERIENSNIKELIVTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:PRK03092 241 LSGPAAERLKNCGAREVVVTDTLPIPEEKRFDKLTVLSIAPLLARAIREVFEDGSVTSLFD 301
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
4-315 |
2.41e-129 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 371.57 E-value: 2.41e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 4 EDGKKLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALK 83
Cdd:PRK04923 2 QDQRNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 84 RASARHITAVVPYYGYARQDRKTRG-REPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYI-N 161
Cdd:PRK04923 82 RASAASVTAVIPYFGYSRQDRRMRSsRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIwR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 162 EKKMEDLIVVSPDLGGVTRARDLADRIG-APIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALK 240
Cdd:PRK04923 162 AYGTDNLIVVSPDVGGVVRARAVAKRLDdADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAAALK 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 546349052 241 EFGAKSVMACVTHAVLTDPACERIENSNIKELIVTNTIDLPEEHKL-PNITSLSVAPLLGEAIMRIFHEVSVSNLF 315
Cdd:PRK04923 242 QRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARAcAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
11-316 |
9.94e-115 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 338.77 E-value: 9.94e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 11 IFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASARHI 90
Cdd:PTZ00145 122 LFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASAKKI 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 91 TAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFF--NVPVDHLFGASILAKYINEKKMEDL 168
Cdd:PTZ00145 202 TAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFgpRVPVDNLEAQLIGLDYFTKKDLYKP 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 169 IVVSPDLGGVTRARDLADRIGA------PIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEF 242
Cdd:PTZ00145 282 VIVSPDAGGVYRARKFQDGLNHrgisdcGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAAKQLKKH 361
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 546349052 243 GAKSVMACVTHAVLTDPACERIENSNIKELIVTNTIDL-PEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFD 316
Cdd:PTZ00145 362 GARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSnKNIDSCKKITKLSVSVLVADAIRRIHQKESLNDLFN 436
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
5-315 |
2.33e-112 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 328.24 E-value: 2.33e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 5 DGKKLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKR 84
Cdd:PRK02458 6 ADKQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 85 ASARHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEKK 164
Cdd:PRK02458 86 ASANTVNVVLPYFGYARQDRIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 165 M--EDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMnLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEF 242
Cdd:PRK02458 166 LsgSDVVVVSPKNSGIKRARSLAEYLDAPIAIIDYAQDDSEREEGY-IIGDVAGKKAILIDDILNTGKTFAEAAKIVERE 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 546349052 243 GAKSVMACVTHAVLTDPACERIENSNIKELIVTNTIDlpEEHKLP-NITSLSVAPLLGEAIMRIFHEVSVSNLF 315
Cdd:PRK02458 245 GATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVA--TKERVPkNVTYLSASELIADAIIRIHERKPLSPLF 316
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
5-317 |
4.24e-104 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 307.61 E-value: 4.24e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 5 DGKKLKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKR 84
Cdd:PRK00553 6 DKSNHVIFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 85 ASARHITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGITRLVTIDLHAGQIQGFFNVPVDHLFGASI-LAKYINEK 163
Cdd:PRK00553 86 GSAKSITAILPYYGYARQDRKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVfLSRVLELL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 164 KMEDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFG 243
Cdd:PRK00553 166 GKKDLVVVSPDYGGVKRARLIAESLELPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQK 245
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 546349052 244 AKSVMACVTHAVLTDPACERIENSNIKELI----VTNTIDLPEEHKLPNITSLSVAPLLGEAIMRIFHEVSVSNLFDK 317
Cdd:PRK00553 246 AKKVCVMATHGLFNKNAIQLFDEAFKKKLIdklfVSNSIPQTKFEKKPQFKVVDLAHLYEEVLLCYANGGSISAIYTR 323
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
9-125 |
4.02e-77 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 231.15 E-value: 4.02e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 9 LKIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPVNDNLIELLVMADALKRASAR 88
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 546349052 89 HITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAG 125
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
10-302 |
8.22e-72 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 223.64 E-value: 8.22e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 10 KIFTGNANPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQpTSYPVNDNLIELLVMADALKRASARH 89
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIIS-TTYPQDENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 90 ITAVVPYYGYARQDRKTRGREPITAKLVADLMQTAGiTRLVTIDLHAGQIQGFFNVPVDHLFGASILAKYINEkKMEDLI 169
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFKPGEPISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGD-KLDDPL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 170 VVSPDLGGVTRARDLADRIGAPIAIIEKKR--PQPGVAKVMNLigNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSV 247
Cdd:PRK00934 158 VLAPDKGALELAKEAAEILGCEYDYLEKTRisPTEVEIAPKNL--DVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKV 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 546349052 248 MACVTHAVLTDPACERIENSNIKELIVTNTIDLPEehklpniTSLSVAPLLGEAI 302
Cdd:PRK00934 236 YVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEV-------SKISVAPLIADLL 283
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
39-317 |
4.12e-48 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 165.51 E-value: 4.12e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 39 RFNNGEVQIMIDESVRGKDVFIVQP-TSYPV-------------NDNLIELLVMADALkRASARHITAVVPYYGYARQDR 104
Cdd:PRK06827 61 RFSNGEAKGEILESVRGKDIYILQDvGNYSVtynmfgeknhmspDDHFQDLKRTIDAI-RGKARRITVIMPFLYESRQHK 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 105 KTrGREPITAKLVADLMQTAGITRLVTIDLHAGQIQ------GFFNVPVDHLFGASILAKYIN-EKKMEDLIVVSPDLGG 177
Cdd:PRK06827 140 RK-GRESLDCALALQELEELGVDNIITFDAHDPRIEnaiplmGFENLYPSYQIIKALLKNEKDlEIDKDHLMVISPDTGA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 178 VTRARDLADRIGAPIAIIEKKRPQPGVAK------VMNLIG-NVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMAC 250
Cdd:PRK06827 219 MDRAKYYASVLGVDLGLFYKRRDYSRVVNgrnpivAHEFLGrDVEGKDVLIVDDMIASGGSMIDAAKELKSRGAKKIIVA 298
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 546349052 251 VTHAVLTDpACERI----ENSNIKELIVTNTIDLPEE--HKlPNITSLSVAPLLGEAIMRIFHEVSVSNLFDK 317
Cdd:PRK06827 299 ATFGFFTN-GLEKFdkayEEGYFDRIIGTNLVYHPEEllSK-PWYIEVDMSKLIARIIDALNHDVSLSKLLDP 369
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
17-307 |
1.40e-43 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 151.24 E-value: 1.40e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 17 NPELAKEICDYLGLPLGEAFVGRFNNGEVQIMIDESVRGKDVFIVQPTSYPvNDNLIELLVMADALKRASARHITAVVPY 96
Cdd:PRK07199 11 NEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVGLVAPY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 97 YGYARQDRKTRGREPITAKLVADLMqTAGITRLVTID--LH-AGQIQGFFNVPVDHLFGASILAKYINEKkMEDLIVVSP 173
Cdd:PRK07199 90 LAYMRQDIAFHPGEAISQRHFARLL-SGSFDRLVTVDphLHrYPSLSEVYPIPAVVLSAAPAIAAWIRAH-VPRPLLIGP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 174 DLGGVTRARDLADRIGAPIAIIEKKR---PQPGVAkVMNLIGnVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMAC 250
Cdd:PRK07199 168 DEESEQWVAAVAERAGAPHAVLRKTRhgdRDVEIS-LPDAAP-WAGRTPVLVDDIVSTGRTLIEAARQLRAAGAASPDCV 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 546349052 251 VTHAVLTDPACERIENSNIKELIVTNTIdlpeehklPNITS-LSVAPLLGEAIMRIFH 307
Cdd:PRK07199 246 VVHALFAGDAYSALAAAGIARVVSTDTV--------PHPSNaISLAPLLAEALRREFD 295
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
153-277 |
1.54e-28 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 106.71 E-value: 1.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 153 ASILAKYINEKKMEDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPG------VAKVMNLIGNVEGKNCIIIDDIV 226
Cdd:cd06223 2 GRLLAEEIREDLLEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGrtpsepYGLELPLGGDVKGKRVLLVDDVI 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 546349052 227 DTAGSLVEGAKALKEFGAKSVMACVTHAVLTDpaCERIENSNIKELIVTNT 277
Cdd:cd06223 82 ATGGTLLAAIELLKEAGAKVVGVAVLLDKPEG--GARELASPGDPVYSLFT 130
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
179-315 |
4.19e-23 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 94.11 E-value: 4.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 179 TRARDLADRIGAPIAIIEKKRPqpgvakvMNLIGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMACVTHAVLTD 258
Cdd:pfam14572 53 YRSRTVSRSLGLPEIIPKEKPP-------MTVVGDVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSS 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 259 PACERIENSNIKELIVTNTIdlPEEHKL---PNITSLSVAPLLGEAIMRIFHEVSVSNLF 315
Cdd:pfam14572 126 DAPRLLEASPIDEVVVTNTI--PHEIQKmqcHKIKTIDISQLIAEAIRRIHNGESMSYLF 183
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
153-254 |
1.80e-17 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 77.79 E-value: 1.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 153 ASILAKYINEKKMEDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKR---PQPGVAKVMNLIGNVEGKNCIIIDDIVDTA 229
Cdd:pfam00156 16 ARLAAQINEDYGGKPDVVVGILRGGLPFAGILARRLDVPLAFVRKVSynpDTSEVMKTSSALPDLKGKTVLIVDDILDTG 95
|
90 100
....*....|....*....|....*
gi 546349052 230 GSLVEGAKALKEFGAKSVMACVTHA 254
Cdd:pfam00156 96 GTLLKVLELLKNVGPKEVKIAVLID 120
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
40-268 |
5.50e-14 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 71.26 E-value: 5.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 40 FNNGEVQIMID--ESVRGKDV-FIvqpTSYPVNDNLIELLVMADALKRASARHITAVVPYYGYARQDRKTRGREPITAKL 116
Cdd:PLN02297 49 FPDGFPNLFINnaHGIRGQHVaFL---ASFSSPAVIFEQLSVIYALPKLFVASFTLVLPFFPTGTSERVEREGDVATAFT 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 117 VADLMQT-----AGITRLVTIDLHAGQIQGFFNVPVDHLF--GASILAKYINEKKMEDLIVVS-PDLGGVTRARDLADri 188
Cdd:PLN02297 126 LARILSNipisrGGPTSLVIFDIHALQERFYFGDNVLPCFesGIPLLKKRLQQLPDSDNIVIAfPDDGAWKRFHKQFE-- 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 189 GAPIAIIEKKRPqpGVAKVMNLI-GNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMACVTHAVLTDPACERIENS 267
Cdd:PLN02297 204 HFPMVVCTKVRE--GDKRIVRIKeGNPAGRHVVIVDDLVQSGGTLIECQKVLAAHGAAKVSAYVTHGVFPNESWERFTHD 281
|
.
gi 546349052 268 N 268
Cdd:PLN02297 282 N 282
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
153-270 |
1.76e-08 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 53.62 E-value: 1.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 153 ASILAKYINEKKMEDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVakvMNLI--GNVEGKNCIIIDDIVDTAG 230
Cdd:COG0461 50 GEALAELIKELGPEFDAVAGPATGGIPLAAAVARALGLPAIFVRKEAKDHGT---GGQIegGLLPGERVLVVEDVITTGG 126
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 546349052 231 SLVEGAKALKEFGAKsVMACVthAVLT--DPACERIENSNIK 270
Cdd:COG0461 127 SVLEAVEALREAGAE-VVGVA--VIVDreEGAAENLEEAGVP 165
|
|
| PRK02277 |
PRK02277 |
orotate phosphoribosyltransferase-like protein; Provisional |
153-279 |
6.66e-08 |
|
orotate phosphoribosyltransferase-like protein; Provisional
Pssm-ID: 235023 [Multi-domain] Cd Length: 200 Bit Score: 51.79 E-value: 6.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 153 ASILAKYINEKKMEDLIVVSPDLGGVTRARDLADRIGAPIAI-IEKKRPQPGVAKVMNLI----GNVEGKNCIIIDDIVD 227
Cdd:PRK02277 72 ASAMADMLEKEDEEVDVVVGIAKSGVPLATLVADELGKDLAIyHPKKWDHGEGEKKTGSFsrnfASVEGKRCVIVDDVIT 151
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 546349052 228 TAGSLVEGAKALKEFGAKSVmACVthaVLTDP-ACERIENSNIKELIVTNTID 279
Cdd:PRK02277 152 SGTTMKETIEYLKEHGGKPV-AVV---VLIDKsGIDEIDGVPVYSLIRVVRVD 200
|
|
| pyrE |
PRK00455 |
orotate phosphoribosyltransferase; Validated |
153-245 |
8.17e-07 |
|
orotate phosphoribosyltransferase; Validated
Pssm-ID: 234771 Cd Length: 202 Bit Score: 48.61 E-value: 8.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 153 ASILAKYINEKKMEDLIVVSPDLGGVTRARDLADRIGAPIAIIEKKRPQPGVAKVMnlIGN-VEGKNCIIIDDIVDTAGS 231
Cdd:PRK00455 51 GRFLAEAIKDSGIEFDVVAGPATGGIPLAAAVARALDLPAIFVRKEAKDHGEGGQI--EGRrLFGKRVLVVEDVITTGGS 128
|
90
....*....|....
gi 546349052 232 LVEGAKALKEFGAK 245
Cdd:PRK00455 129 VLEAVEAIRAAGAE 142
|
|
| HptA |
COG0634 |
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; ... |
213-251 |
2.33e-05 |
|
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Hypoxanthine-guanine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 440399 Cd Length: 176 Bit Score: 44.25 E-value: 2.33e-05
10 20 30
....*....|....*....|....*....|....*....
gi 546349052 213 NVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMACV 251
Cdd:COG0634 88 DIEGRDVLIVEDIIDTGLTLSYLLELLKSRGPASVKIAT 126
|
|
| PLN02238 |
PLN02238 |
hypoxanthine phosphoribosyltransferase |
213-263 |
1.22e-04 |
|
hypoxanthine phosphoribosyltransferase
Pssm-ID: 215132 Cd Length: 189 Bit Score: 42.33 E-value: 1.22e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 546349052 213 NVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSVMACvthaVLTDPACER 263
Cdd:PLN02238 94 DVKGKHVLLVEDIVDTGNTLSALVAHLEAKGAASVSVC----ALLDKRARR 140
|
|
| Hpt1 |
COG2236 |
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ... |
176-251 |
3.99e-04 |
|
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 441837 [Multi-domain] Cd Length: 153 Bit Score: 40.21 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 176 GGVTRARDLADRIGAP-IAII--------EKKRPQPGVAKVMNliGNVEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKS 246
Cdd:COG2236 41 GGLVPARILADALGVPdLASIrvssytgtAKRLEEPVVKGPLD--EDLAGKRVLIVDDVADTGRTLEAVRDLLKEAGPAE 118
|
....*
gi 546349052 247 VMACV 251
Cdd:COG2236 119 VRTAV 123
|
|
| PRK05793 |
PRK05793 |
amidophosphoribosyltransferase; Provisional |
167-276 |
1.23e-03 |
|
amidophosphoribosyltransferase; Provisional
Pssm-ID: 235611 [Multi-domain] Cd Length: 469 Bit Score: 40.40 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 167 DLIVVSPDlGGVTRARDLADRIGAPIAI--IEKK-------------RPQPGVAKVMNLIGNVEGKNCIIIDD-IV--DT 228
Cdd:PRK05793 290 DIVIGVPD-SGIPAAIGYAEASGIPYGIgfIKNKyvgrtfiapsqelRERAVRVKLNPLKVNVEGKRVVLIDDsIVrgTT 368
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 546349052 229 AGSLVEgakALKEFGAKSVMACVTHAVLTDPACERIENSNIKELIVTN 276
Cdd:PRK05793 369 SKRLVE---LLRKAGAKEVHFRVSSPPVKYPCYFGIDTPYRKELIGAN 413
|
|
| ComFC |
COG1040 |
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General ... |
181-247 |
3.94e-03 |
|
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General function prediction only];
Pssm-ID: 440662 [Multi-domain] Cd Length: 196 Bit Score: 37.88 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 546349052 181 ARDLADRIGAPIA--IIEKKR---PQPG---------VAKVMNLIGN--VEGKNCIIIDDIVdTAGS-LVEGAKALKEFG 243
Cdd:COG1040 104 ARALARALGIPVLpdLLRRVRatpSQAGlsraerrrnLRGAFAVRPParLAGKHVLLVDDVL-TTGAtLAEAARALKAAG 182
|
....
gi 546349052 244 AKSV 247
Cdd:COG1040 183 AARV 186
|
|
| PTZ00149 |
PTZ00149 |
hypoxanthine phosphoribosyltransferase; Provisional |
214-247 |
3.96e-03 |
|
hypoxanthine phosphoribosyltransferase; Provisional
Pssm-ID: 240293 Cd Length: 241 Bit Score: 38.21 E-value: 3.96e-03
10 20 30
....*....|....*....|....*....|....
gi 546349052 214 VEGKNCIIIDDIVDTAGSLVEGAKALKEFGAKSV 247
Cdd:PTZ00149 148 LKDKHVLIVEDIIDTGNTLVKFCEYLKKFEPKTI 181
|
|
| |
