|
Name |
Accession |
Description |
Interval |
E-value |
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-395 |
2.13e-153 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 439.30 E-value: 2.13e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 1 MSRKCIIGQSGGPTVVINATLAGVIQGALK-ADYEKIYGMINGIDGLLDEKMVDLSSfKDQKNLFKLIHTPAMYLGSCRY 79
Cdd:PRK14072 2 MKGNALYAQSGGPTAVINASAAGVIEEARKhKKIGKVYGARNGIIGILDEDLIDLSK-ESDEALAALAHTPSGALGSCRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 80 KI--FEKDQSIKQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSACH 157
Cdd:PRK14072 81 KLksLEEDRAEYERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQLAKKMGYPIRCIGIPKTIDNDLPGTDHCPGFGSAAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 158 YVATSLCEIAFDSVIYPIKS-VTIVEIMGRDAGWLTASAQLVNEVYPDSIDLIYMPENIFDENDFLEQIKDKLKKKDHCI 236
Cdd:PRK14072 161 YIATSVLEAALDVAAMANTSkVFILEVMGRHAGWLAAAAALAKQNPDDAPHLIYLPERPFDEEKFLADVRAIVKRYGYCV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 237 IAVSEGIRDQYGMCVSlDSGIQKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRCAAHLASYIDIENALRIGSY 316
Cdd:PRK14072 241 VVVSEGIRDADGKFIA-EAGLAEDAFGHAQLGGVAPVLANLIKEKLGKKVHWAVLDYLQRAARHIASKTDVEEAYAVGKA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 317 AINCALDKRTGIMVTISKNRNEFLLS---HVDIHKVANHVKPFPLEWIDEKNKKIKKEYIDYVVPLI-------YKSGqi 386
Cdd:PRK14072 320 AVEYALAGKNGVMPAIRRTSDDPYKWkigLVPLSKVANKEKKMPPEFINEDGNGITEAFRRYLRPLIqgepyppYKNG-- 397
|
....*....
gi 537995004 387 eLPQYLQLN 395
Cdd:PRK14072 398 -LPDYVRLK 405
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
3-363 |
1.32e-109 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 325.11 E-value: 1.32e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 3 RKCIIGQSGGPTVVINATLAGVIQGALKADYEkIYGMINGIDGLLDEKMVDLSSfkdqKNLFKLIHTPAMYLGSCRYKIF 82
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKYGIE-VYGIRDGYEGLLEGDIIDLTR----EDVSGILQRGGTILGSSRSKPF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 83 eKDQSIKQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYakvcnCPINFIGIPKTIDNDLMNIDYTPGYPSACHYVATS 162
Cdd:COG0205 77 -KTEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEE-----YGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 163 LCEIAFDSviypiKS---VTIVEIMGRDAGWLTASAQLVNEVypdsiDLIYMPENIFDENDFLEQIKDKLKK-KDHCIIA 238
Cdd:COG0205 151 IDRLRDTA-----ASherVFVVEVMGRHAGWLALAAGLAGGA-----DLILIPEVPFDLDKLLEKLKERRKRgKGYSIIV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 239 VSEGIRDQYGMCVSLDSgiqKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRCAAhlASYIDIENALRIGSYAI 318
Cdd:COG0205 221 VAEGAGDEDGEAVLEAD---TDAFGHVRLGGIGEYLAKEIEERTGIETRVTVLGHLQRGGS--PSAFDRVLASRLGAAAV 295
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 537995004 319 NCALDKRTGIMVTISKNRneflLSHVDIHKVANHVKPFPL--EWIDE 363
Cdd:COG0205 296 ELLLEGKTGVMVGIRRGE----IVLVPLEEVANKEKPVDPdsPLIQL 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
7-319 |
1.31e-62 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 202.18 E-value: 1.31e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 7 IGQSGGPTVVINATLAGVIQGALKADYEkIYGMINGIDGLLDEKMVDLssfkDQKNLFKLIHTPAMYLGSCRYKIFEKDQ 86
Cdd:pfam00365 4 ILTSGGDAPGMNAAIRAVVRTAIYRGHE-VYGIRNGYEGLVEGDIDEL----TWRDVSGILNRGGTILGTSRSKPFKTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 87 SIKqRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKvcncpINFIGIPKTIDNDLMNIDYTPGYPSACHYVATSLCEI 166
Cdd:pfam00365 79 GRE-KIAENLKKLGIDALVVIGGDGSLTGANKLSEERG-----IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 167 AFDSviypiKS---VTIVEIMGRDAGWLTASAQLVNEVypdsiDLIYMPENIFDENDFLEQIKDKLKKKDHCIIAVSEGI 243
Cdd:pfam00365 153 RDTA-----SShnrVFVVEVMGRHCGWLALMAGLAGGA-----DAILIPEIPFDIEELCEKIKELRKGKRFSIIVVAEGA 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 537995004 244 RDqygmcvsldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQLSTLQRCAAhlASYIDIENALRIGSYAIN 319
Cdd:pfam00365 223 SD-------------------------GEFLAKLIEEGTGIETRVTVLGHVQRGGT--PSAFDRILATRLGVKAVE 271
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
10-336 |
7.19e-37 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 136.28 E-value: 7.19e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGAL-KADYEkIYGMINGIDGLLDEKMVDLSsfkDQKNLFKLIHTPAMYLGSCRYKIFEKDQSI 88
Cdd:TIGR02483 7 GGGDCPGLNAVIRGVVRRAIaEYGWE-VIGIRDGWRGLLEGDTVPLL---DLEDVRGILPRGGTILGSSRTNPFKYEEDG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 89 KQRIITILNKYEITDFFYIGGNDSMDTIEKLStyakvcNCPINFIGIPKTIDNDLMNIDYTPGYPSACHyVATSlceiAF 168
Cdd:TIGR02483 83 DDKIVANLKELGLDALIAIGGDGTLGIARRLA------DKGLPVVGVPKTIDNDLEATDYTFGFDTAVE-IATE----AL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 169 DSVIYPIKS---VTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDFLEQIKDK-LKKKDHCIIAVSEGIR 244
Cdd:TIGR02483 152 DRLHTTAEShhrVMVVEVMGRHAGWIALHSGIAG-----GADVILIPEIPFDIDSVCEKVRERfARGKRFAIVVVAEGAK 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 245 DQYGMCVSLDSGiqKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRCAAhlASYIDIENALRIGSYAINCALDK 324
Cdd:TIGR02483 227 PKGGEMVVQEGV--KDAFGHVRLGGIGNWLAEEIERRTGIETRATVLGHLQRGGS--PSAFDRVLATRFGVAAVDLVHEG 302
|
330
....*....|..
gi 537995004 325 RTGIMVTISKNR 336
Cdd:TIGR02483 303 QFGHMVALRGTD 314
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
10-360 |
1.12e-33 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 128.19 E-value: 1.12e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGAlKADYEKIYGMINGIDGLLDEKMVDLssfkDQKNLFKLIHTPAMYLGSCRYKIFEkDQSIK 89
Cdd:cd00363 8 SGGDAPGMNAAIRGVVRSA-IAEGLEVYGIYEGYAGLVEGDIKEL----DWESVSDIINRGGTIIGSARCKEFR-TEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 90 QRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSACHYVATSLCEIAFD 169
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 170 SVIYpiKSVTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDFlEQIKDKLKK-----KDHCIIAVSEGIR 244
Cdd:cd00363 162 ASSH--QRTFVVEVMGRHCGDIALEAGLAT-----GADIIFIPEEPAADEWE-EEMVDVIKKrrergKRHGIVIVAEGAI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 245 DQYGMCVSldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQLSTLQRCAahLASYIDIENALRIGSYAINCALDK 324
Cdd:cd00363 234 DFIPKPIT------------------EKLLAKLVEERLGFDTRATVLGHVQRGG--TPTAFDRILASRLGAEAVELLLEG 293
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 537995004 325 RTGIMVTIsKNRNEFLLSHVDI---------HKVANHVKPFPLEW 360
Cdd:cd00363 294 TGGTPVGI-QNLNENQVVRHPLteavnmtkrVGVDLEGRPFKKFA 337
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-395 |
2.13e-153 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 439.30 E-value: 2.13e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 1 MSRKCIIGQSGGPTVVINATLAGVIQGALK-ADYEKIYGMINGIDGLLDEKMVDLSSfKDQKNLFKLIHTPAMYLGSCRY 79
Cdd:PRK14072 2 MKGNALYAQSGGPTAVINASAAGVIEEARKhKKIGKVYGARNGIIGILDEDLIDLSK-ESDEALAALAHTPSGALGSCRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 80 KI--FEKDQSIKQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSACH 157
Cdd:PRK14072 81 KLksLEEDRAEYERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQLAKKMGYPIRCIGIPKTIDNDLPGTDHCPGFGSAAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 158 YVATSLCEIAFDSVIYPIKS-VTIVEIMGRDAGWLTASAQLVNEVYPDSIDLIYMPENIFDENDFLEQIKDKLKKKDHCI 236
Cdd:PRK14072 161 YIATSVLEAALDVAAMANTSkVFILEVMGRHAGWLAAAAALAKQNPDDAPHLIYLPERPFDEEKFLADVRAIVKRYGYCV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 237 IAVSEGIRDQYGMCVSlDSGIQKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRCAAHLASYIDIENALRIGSY 316
Cdd:PRK14072 241 VVVSEGIRDADGKFIA-EAGLAEDAFGHAQLGGVAPVLANLIKEKLGKKVHWAVLDYLQRAARHIASKTDVEEAYAVGKA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 317 AINCALDKRTGIMVTISKNRNEFLLS---HVDIHKVANHVKPFPLEWIDEKNKKIKKEYIDYVVPLI-------YKSGqi 386
Cdd:PRK14072 320 AVEYALAGKNGVMPAIRRTSDDPYKWkigLVPLSKVANKEKKMPPEFINEDGNGITEAFRRYLRPLIqgepyppYKNG-- 397
|
....*....
gi 537995004 387 eLPQYLQLN 395
Cdd:PRK14072 398 -LPDYVRLK 405
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
3-363 |
1.32e-109 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 325.11 E-value: 1.32e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 3 RKCIIGQSGGPTVVINATLAGVIQGALKADYEkIYGMINGIDGLLDEKMVDLSSfkdqKNLFKLIHTPAMYLGSCRYKIF 82
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKYGIE-VYGIRDGYEGLLEGDIIDLTR----EDVSGILQRGGTILGSSRSKPF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 83 eKDQSIKQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYakvcnCPINFIGIPKTIDNDLMNIDYTPGYPSACHYVATS 162
Cdd:COG0205 77 -KTEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEE-----YGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 163 LCEIAFDSviypiKS---VTIVEIMGRDAGWLTASAQLVNEVypdsiDLIYMPENIFDENDFLEQIKDKLKK-KDHCIIA 238
Cdd:COG0205 151 IDRLRDTA-----ASherVFVVEVMGRHAGWLALAAGLAGGA-----DLILIPEVPFDLDKLLEKLKERRKRgKGYSIIV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 239 VSEGIRDQYGMCVSLDSgiqKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRCAAhlASYIDIENALRIGSYAI 318
Cdd:COG0205 221 VAEGAGDEDGEAVLEAD---TDAFGHVRLGGIGEYLAKEIEERTGIETRVTVLGHLQRGGS--PSAFDRVLASRLGAAAV 295
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 537995004 319 NCALDKRTGIMVTISKNRneflLSHVDIHKVANHVKPFPL--EWIDE 363
Cdd:COG0205 296 ELLLEGKTGVMVGIRRGE----IVLVPLEEVANKEKPVDPdsPLIQL 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
7-319 |
1.31e-62 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 202.18 E-value: 1.31e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 7 IGQSGGPTVVINATLAGVIQGALKADYEkIYGMINGIDGLLDEKMVDLssfkDQKNLFKLIHTPAMYLGSCRYKIFEKDQ 86
Cdd:pfam00365 4 ILTSGGDAPGMNAAIRAVVRTAIYRGHE-VYGIRNGYEGLVEGDIDEL----TWRDVSGILNRGGTILGTSRSKPFKTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 87 SIKqRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKvcncpINFIGIPKTIDNDLMNIDYTPGYPSACHYVATSLCEI 166
Cdd:pfam00365 79 GRE-KIAENLKKLGIDALVVIGGDGSLTGANKLSEERG-----IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 167 AFDSviypiKS---VTIVEIMGRDAGWLTASAQLVNEVypdsiDLIYMPENIFDENDFLEQIKDKLKKKDHCIIAVSEGI 243
Cdd:pfam00365 153 RDTA-----SShnrVFVVEVMGRHCGWLALMAGLAGGA-----DAILIPEIPFDIEELCEKIKELRKGKRFSIIVVAEGA 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 537995004 244 RDqygmcvsldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQLSTLQRCAAhlASYIDIENALRIGSYAIN 319
Cdd:pfam00365 223 SD-------------------------GEFLAKLIEEGTGIETRVTVLGHVQRGGT--PSAFDRILATRLGVKAVE 271
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
10-368 |
1.97e-40 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 145.61 E-value: 1.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGG--PTvvINATLAGVIQGALKADYEkIYGMINGIDGLLDEKMVDLssfkDQKNLFKLIHTPAMYLGSCRYKIFeKDQS 87
Cdd:PRK03202 9 SGGdaPG--MNAAIRAVVRTAISEGLE-VYGIYDGYAGLLEGDIVKL----DLKSVSDIINRGGTILGSARFPEF-KDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 88 IKQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAkvcncpINFIGIPKTIDNDLMNIDYTPGYPSAchyvatslCEIA 167
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHG------IPVIGLPGTIDNDIAGTDYTIGFDTA--------LNTA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 168 FDSvIYPIKS-------VTIVEIMGRDAGWLTASAQLVNEVypdsiDLIYMPENIFDENDFLEQIKDKLKK-KDHCIIAV 239
Cdd:PRK03202 147 VEA-IDRLRDtassherVFIVEVMGRHAGDLALHAGIAGGA-----EVILIPEVPFDIEELCAKIKKGRERgKKHAIIVV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 240 SEGIRDqygmcvsldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQLSTLQR----CAAhlasyiDIENALRIGS 315
Cdd:PRK03202 221 AEGVMP-------------------------AEELAKEIEERTGLETRVTVLGHIQRggspTAF------DRVLASRMGA 269
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 537995004 316 YAINCALDKRTGIMVTISKNRneflLSHVDIHK-VANHVKPFPLEWIdEKNKKI 368
Cdd:PRK03202 270 HAVELLLEGKGGRMVGIQNNK----IVHVPIEEaVENMKHPFDKDLY-ELAKKL 318
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
10-336 |
7.19e-37 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 136.28 E-value: 7.19e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGAL-KADYEkIYGMINGIDGLLDEKMVDLSsfkDQKNLFKLIHTPAMYLGSCRYKIFEKDQSI 88
Cdd:TIGR02483 7 GGGDCPGLNAVIRGVVRRAIaEYGWE-VIGIRDGWRGLLEGDTVPLL---DLEDVRGILPRGGTILGSSRTNPFKYEEDG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 89 KQRIITILNKYEITDFFYIGGNDSMDTIEKLStyakvcNCPINFIGIPKTIDNDLMNIDYTPGYPSACHyVATSlceiAF 168
Cdd:TIGR02483 83 DDKIVANLKELGLDALIAIGGDGTLGIARRLA------DKGLPVVGVPKTIDNDLEATDYTFGFDTAVE-IATE----AL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 169 DSVIYPIKS---VTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDFLEQIKDK-LKKKDHCIIAVSEGIR 244
Cdd:TIGR02483 152 DRLHTTAEShhrVMVVEVMGRHAGWIALHSGIAG-----GADVILIPEIPFDIDSVCEKVRERfARGKRFAIVVVAEGAK 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 245 DQYGMCVSLDSGiqKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRCAAhlASYIDIENALRIGSYAINCALDK 324
Cdd:TIGR02483 227 PKGGEMVVQEGV--KDAFGHVRLGGIGNWLAEEIERRTGIETRATVLGHLQRGGS--PSAFDRVLATRFGVAAVDLVHEG 302
|
330
....*....|..
gi 537995004 325 RTGIMVTISKNR 336
Cdd:TIGR02483 303 QFGHMVALRGTD 314
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
10-360 |
1.12e-33 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 128.19 E-value: 1.12e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGAlKADYEKIYGMINGIDGLLDEKMVDLssfkDQKNLFKLIHTPAMYLGSCRYKIFEkDQSIK 89
Cdd:cd00363 8 SGGDAPGMNAAIRGVVRSA-IAEGLEVYGIYEGYAGLVEGDIKEL----DWESVSDIINRGGTIIGSARCKEFR-TEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 90 QRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSACHYVATSLCEIAFD 169
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 170 SVIYpiKSVTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDFlEQIKDKLKK-----KDHCIIAVSEGIR 244
Cdd:cd00363 162 ASSH--QRTFVVEVMGRHCGDIALEAGLAT-----GADIIFIPEEPAADEWE-EEMVDVIKKrrergKRHGIVIVAEGAI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 245 DQYGMCVSldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQLSTLQRCAahLASYIDIENALRIGSYAINCALDK 324
Cdd:cd00363 234 DFIPKPIT------------------EKLLAKLVEERLGFDTRATVLGHVQRGG--TPTAFDRILASRLGAEAVELLLEG 293
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 537995004 325 RTGIMVTIsKNRNEFLLSHVDI---------HKVANHVKPFPLEW 360
Cdd:cd00363 294 TGGTPVGI-QNLNENQVVRHPLteavnmtkrVGVDLEGRPFKKFA 337
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
10-362 |
1.04e-32 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 125.21 E-value: 1.04e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGALKADYEkIYGMINGIDGLLDEKMVDLssfkDQKNLFKLIHTPAMYLGSCRYKIFeKDQSIK 89
Cdd:cd00763 8 SGGDAPGMNAAIRGVVRSAIAEGLE-VYGIRDGYAGLIAGDIVPL----DRYSVSDIINRGGTFLGSARFPEF-KDEEGQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 90 QRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAkvcncpINFIGIPKTIDNDLMNIDYTPGYPSACHYVATSLCEIAFD 169
Cdd:cd00763 82 AKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHG------FPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 170 SVIYpiKSVTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDFLEQIKDKLKK-KDHCIIAVSEGIRDQYG 248
Cdd:cd00763 156 SSSH--QRISVVEVMGRHCGDIALAAGIAG-----GAEFIVIPEAEFDREEVANRIKAGIERgKKHAIVVVAEGVYDVDE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 249 mcvsldsgiqkdafghlsnngcsnyLKKLIGDHLGCKVRAIQLSTLQRCAAHLASyiDIENALRIGSYAINCALDKRTGI 328
Cdd:cd00763 229 -------------------------LAKEIEEATGFETRATVLGHIQRGGSPTAF--DRILASRMGAYAVELLLAGKGGL 281
|
330 340 350
....*....|....*....|....*....|....
gi 537995004 329 MVTIsknRNEFLLSHvDIHKVANHVKPFPLEWID 362
Cdd:cd00763 282 AVGI---QNEQLVHH-DIIDAIENMKPFKKDWLA 311
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
24-278 |
7.66e-25 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 105.51 E-value: 7.66e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 24 VIQG---ALKADY--EKIYGMINGIDGLLDEKMVDLSSfkdqkNLFKLIH-TPAMYLGSCRYKifekdQSIKQrIITILN 97
Cdd:PTZ00286 105 VIRElvmNLINNYgvKTIYGAKYGYKGLYKEDWIKLDP-----KDVKTIHrLGGTILGSSRGG-----FDPKV-MVDTLI 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 98 KYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSachyvATSLCEIAFDSVIYPIKS 177
Cdd:PTZ00286 174 RHGINILFTLGGDGTHRGALAIYKELRRRKLNISVVGIPKTIDNDIPIIDESFGFQT-----AVEEAQNAIRAAYVEAKS 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 178 ----VTIVEIMGRDAGWLTASAQLVNEvypdSIDLIYMPENIFDENDFLEQIKDKLKKKDHCIIAVSEGIRDQYgMCVSL 253
Cdd:PTZ00286 249 akngVGIVKLMGRDSGFIALHASVASA----DVNVCLIPEFDIPLEGVLEYIEQRLQKKGHCVIVVAEGAGQSL-KDADL 323
|
250 260
....*....|....*....|....*
gi 537995004 254 DSGiqKDAFGHLSNNGCSNYLKKLI 278
Cdd:PTZ00286 324 DLG--TDASGNKKLWDIGVYLKDEI 346
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
84-331 |
8.93e-22 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 95.52 E-value: 8.93e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 84 KDQSikQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKvcncpINFIGIPKTIDNDLMNIDYTPGYPSACHyVATSl 163
Cdd:PRK14071 93 RDRS--QEIIDGYHSLGLDALIGIGGDGSLAILRRLAQQGG-----INLVGIPKTIDNDVGATEVSIGFDTAVN-IATE- 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 164 ceiAFDSVIYPIKS---VTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDFLEQIKDKLKK-KDHCIIAV 239
Cdd:PRK14071 164 ---ALDRLHFTAAShnrVMILEVMGRDAGHIALAAGIAG-----GADVILIPEIPYTLENVCKKIRERQEEgKNFCLVVV 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 240 SEGIRDQYGMCVSldsgiQKDAFGHLSNNGCSNYLKKLIGDHLGCKVRAIQLSTLQRcaAHLASYIDIENALRIGSYAIN 319
Cdd:PRK14071 236 SEAVRTEEGEQVT-----KTQALGEDRYGGIGQYLAEQIAERTGAETRVTVLGHIQR--GGIPSPRDRLLASAFGVAAVD 308
|
250
....*....|..
gi 537995004 320 CALDKRTGIMVT 331
Cdd:PRK14071 309 LIAQGKFDRMVA 320
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
96-355 |
1.38e-18 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 86.85 E-value: 1.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 96 LNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSAChYVATSLCEIAFDSVIYPI 175
Cdd:PRK06830 168 LERMNINILFVIGGDGTLRGASAIAEEIERRGLKISVIGIPKTIDNDINFIQKSFGFETAV-EKATEAIRCAHVEANGAP 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 176 KSVTIVEIMGRDAGWLTASAQL----VNEVypdsidLIymPENIFD---ENDFLEQIKDKLKKKDHCIIAVSEGIRDQYg 248
Cdd:PRK06830 247 NGIGLVKLMGRHSGFIAAYAALaskdVNFV------LI--PEVPFDlegPNGLLAALEKRLAERGHAVIVVAEGAGQEL- 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 249 mcvsLDSGIQKDAFGHLSNNGCSNYLKKLIGDHlgCKVRAIQLsTLQrcaahlasYID--------IENA------LRIG 314
Cdd:PRK06830 318 ----FDDTGETDASGNPKLGDIGLFLKDRIKEY--FKARGIPI-NLK--------YIDpsyiirsvPANAndsvycGFLG 382
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 537995004 315 SYAINCALDKRTGiMVtISKNRNEFLlsHVDIHKVA---NHVKP 355
Cdd:PRK06830 383 QNAVHAAMAGKTG-MV-VGRWNNRFV--HLPIDLAVskrKKVNP 422
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
107-356 |
1.02e-15 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 78.13 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 107 IGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSACHYVAtslceIAFDSVI-----YPiKSVTIV 181
Cdd:PRK06555 119 IGGDDTNTTAADLAAYLAENGYDLTVVGLPKTIDNDVVPIRQSLGAWTAAEQGA-----RFFDNVInehsaNP-RMLIIH 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 182 EIMGRDAGWLTASAQLV-------NEVYPD--------SIDLIYMPENIFDENDFLEQIKDKLKKKDHCIIAVSEgirdq 246
Cdd:PRK06555 193 EVMGRNCGWLTAATARAyrewldrQEYVPGfglsaerwDIHAVYLPEMAFDLEAEAERLKAVMDEVGNVNIFLSE----- 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 247 yGMCVS------LDSG--IQKDAFGHLS----NNGcsNYLKKLIGDHLGCKVRAIQLST-LQRCAAhlASYIDIENALRI 313
Cdd:PRK06555 268 -GAGLDaivaemEAAGeeVKRDAFGHVKldtiNPG--AWFAKQFAELLGAEKVMVQKSGyFARSAP--ANAEDLRLIKSM 342
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 537995004 314 GSYAINCALDKRTGimVTISKNRNEFLLSHVDIHKVANHvKPF 356
Cdd:PRK06555 343 VDLAVECALRGVSG--VIGHDEEQGGKLRAIEFPRIKGG-KAF 382
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
4-354 |
6.15e-12 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 67.36 E-value: 6.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 4 KCI-IGQSGGPTVVINATLAGVIQGALK------ADYEKIYGMINGIDGLLDEKMVDLSSfkdqknlfkLIHTPAMYLGS 76
Cdd:TIGR02478 1 KRIaVLTSGGDAQGMNAAVRAVVRMAIYvgcrvyAIREGYQGLVDGGDNIEEAQWEDVRG---------ILSLGGTIIGT 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 77 CRYKIF-EKDQSIKQRIITILNKyeITDFFYIGGNDSM-----------DTIEKLSTYAKVCN------CPINFIGIPKT 138
Cdd:TIGR02478 72 ARCKEFrERPGRLKAARNLVSNG--IDALVVIGGDGSLtgadlfreewpSLLEELVDTGKITAeqaeehRHLTIVGLVGS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 139 IDNDLMNIDYTPGYPSACHYVatslCEiAFDSVIYPIKS---VTIVEIMGRDAGWLTASAQLVNEVypdsiDLIYMPENI 215
Cdd:TIGR02478 150 IDNDMCGTDMTIGADSALHRI----CE-AIDAISSTAQShqrAFVVEVMGRHCGYLALMAAIATGA-----DYVFIPERP 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 216 FDENdFLEQIKDKLKK-----KDHCIIAVSEGIRDQYGMCVSldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQ 290
Cdd:TIGR02478 220 PEEG-WEDQLCHKLKRnrkagKRKTIVIVAEGAIDRDLNPIT------------------SEDVKDVLVERLGLDTRITV 280
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 291 LSTLQRCAAhlASYIDIENALRIGSYAINCALD---KRTGIMVTISKN---RNEFLLSHVDIHKVANHVK 354
Cdd:TIGR02478 281 LGHVQRGGA--PSAFDRILATRQGVEAVLAVLEstpETPSPVISLRGNkivRKPLVEAVAQTKTVAKAIE 348
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
10-156 |
1.31e-11 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 66.10 E-value: 1.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTvvinatlAG---VIQG---ALKA--DYEKIYGMINGIDGLLDEKMVDL--SSFKDQKNL--FKLIhtpamylGSC 77
Cdd:PRK07085 78 SGGQA-------PGghnVIAGlfdGLKKlnPDSKLFGFIGGPLGLLNGKYIEIteEVIDEYRNTggFDMI-------GSG 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 78 RYKIFEKDQsiKQRIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMN--IDYTPGYPSA 155
Cdd:PRK07085 144 RTKIETEEQ--KEACLETVKKLKLDGLVIIGGDDSNTNAAILAEYFAKHGCKTQVIGVPKTIDGDLKNefIETSFGFDTA 221
|
.
gi 537995004 156 C 156
Cdd:PRK07085 222 T 222
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
10-243 |
1.08e-10 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 63.52 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGALKADYE-KIYGMINGIDGLLDEKMVDLSSfkDQKNLFKLIHTPAMyLGSCRYKIFEKDQSI 88
Cdd:PTZ00287 185 SGGPAPGGHNVISGIYDYAKRYNEQsQVIGFLGGIDGLYSKNYVTITD--SLMNRFRNLGGFNM-LWSGRGKVRNKDDLI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 89 KqrIITILNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMN--IDYTPGYPSACHY---VATSL 163
Cdd:PTZ00287 262 A--IENIVAKLKLNGLVIIGGDGSNSNAALISEYFAERQIPISIIGIPKTIDGDLKSeaIEISFGFDTATKTyseVIGNL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 164 C-EIAFDSVIYpiksvTIVEIMGRDAGWLTASAQLvnEVYPdsiDLIYMPENIFDENDFLEQI---------KDKLKKKD 233
Cdd:PTZ00287 340 CtDVKTGHNVY-----HVVRVMGRSASHVVLECAL--QTRP---NIVLIGEEVEKENLSLKDIvsnivntilKRRSLNKN 409
|
250
....*....|
gi 537995004 234 HCIIAVSEGI 243
Cdd:PTZ00287 410 YGVILIPEGL 419
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
34-242 |
1.94e-10 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 62.14 E-value: 1.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 34 EKIYGMINGIDGLLDEKMVDLSSFKdqkNLFKLIH-TPAMYLGSCR--YKIFEKDQSIKQRIITILnkyeitdfFYIGGN 110
Cdd:PLN02884 85 KNIVGIPFGYRGFFEKGLSEMPLSR---KVVQNIHlSGGSLLGVSRggAKTSDIVDSIEARGINML--------FVLGGN 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 111 DSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMNIDYTPGYPSACHyVATSLCEIAFDSVIYPIKSVTIVEIMGRDAGW 190
Cdd:PLN02884 154 GTHAGANAIHNECRKRKMKVSVVGVPKTIDNDILLMDKTFGFDTAVE-EAQRAINSAYIEAHSAYHGIGLVKLMGRSSGF 232
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 537995004 191 LTASAQLVNevypDSIDLIYMPENIFD---ENDFLEQIKDKLKKKDHCIIAVSEG 242
Cdd:PLN02884 233 IAMHASLAS----GQVDICLIPEVPFTldgPNGVLRHLEHLIETKGSAVVCVAEG 283
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
35-243 |
2.72e-09 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 59.22 E-value: 2.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 35 KIYGMINGIDGLLDEKMVDL-----SSFKDQKNlFKLIhtpamylGSCRYKIFEKDQsiKQRIITILNKYEITDFFYIGG 109
Cdd:PTZ00468 136 QLFGFLGGPEGVYSERYRELteddiNGILNQGG-FNII-------CSGRHKIETEEQ--MRASLEICEKLKLHGLVVIGG 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 110 NDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMN--IDYTPGYPSACHYVATSLCEIaFDSVIYPIKSVTIVEIMGRD 187
Cdd:PTZ00468 206 DDSNTNAAVLAEYFKRNSSSTVVVGCPKTIDGDLKNevIETSFGYDTAVKTYSEQIGSI-MDAIKTEGYGYYFVRLMGRS 284
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 537995004 188 AGWLTASAQLvnEVYPdsiDLIYMPENIFDENDFLEQIKDKLKK---------KDHCIIAVSEGI 243
Cdd:PTZ00468 285 ASHITLECGL--QTRA---NMILIGEEIKEENRSLMSIVDEIVEmilkrdslgKKHGIVLLPEGL 344
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
134-263 |
1.28e-08 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 56.68 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 134 GIPKTIDNDLMNIDYTPGYPSA----------CHYVATSLceiafdsviypIKSVTIVEIMGRDAGWLTASAQLVNEvyp 203
Cdd:PLN02564 210 GIPKTIDNDIPVIDKSFGFDTAveeaqrainaAHVEAESV-----------ENGIGLVKLMGRYSGFIAMYATLASR--- 275
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 537995004 204 dSIDLIYMPENIF---DENDFLEQIKDKLKKKDHCIIAVSEGIRDQYgMCVSLDSGIQKDAFG 263
Cdd:PLN02564 276 -DVDCCLIPESPFyleGKGGLFEFIEKRLKENGHMVIVVAEGAGQDL-IAESMESSDLQDASG 336
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
10-296 |
1.29e-08 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 56.75 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGALK------ADYEKIYGMINGIDGLldeKMVDlssFKDQKNLFKLIHTpamYLGSCRYKIFE 83
Cdd:cd00764 11 SGGDAQGMNAAVRAVVRMGIYvgakvfFVYEGYEGLVKGGDYI---KQAE---WESVSNWLQEGGT---IIGSARCKEFR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 84 KDQSIKQRIITILnKYEITDFFYIGGNDSM-----------DTIEKLSTYAKVCNCP------INFIGIPKTIDNDLMNI 146
Cdd:cd00764 82 EREGRLQAAYNLI-QRGITNLCVIGGDGSLtgadlfrsewpSLLEELVKDGKITEEEvakyqhLNIVGMVGSIDNDFCGT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 147 DYTPGYPSACHYVatslCEIaFDSVIYPIKS---VTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDEnDFLE 223
Cdd:cd00764 161 DMTIGTDSALHRI----CEV-VDAITTTAQShqrTFVLEVMGRHCGYLALVSGLAT-----GADWIFIPERPPED-GWED 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 537995004 224 QIKDKL-----KKKDHCIIAVSEGIRDQYGMCVSldsgiqkdafghlsnngcSNYLKKLIGDHLGCKVRAIQLSTLQR 296
Cdd:cd00764 230 QMCRRLsehrsRGKRLNIIIVAEGAIDDQLKPIT------------------SEDVKDLVVERLGLDTRVTTLGHVQR 289
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
10-192 |
1.77e-06 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 49.87 E-value: 1.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 10 SGGPTVVINATLAGVIQGALK-ADYEKIYGMINGIDGLLDEKMVDLS-----SFKDQKNlFKLIhtpamylGSCRYKIfE 83
Cdd:cd00765 80 SGGQAPGGHNVISGLFDYLKErAKGSTLYGFKGGPAGILKCDYIELNaeyiqPYRNTGG-FDMI-------CSGRTKI-E 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 84 KDQSIKQRIITIlNKYEITDFFYIGGNDSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDLMN--IDYTPGYPSACHYVAT 161
Cdd:cd00765 151 TEDQFKQAEETA-KKLDLDALVVIGGDDSNTNAALLAENFRSKGLKTRVIGVPKTIDGDLKNkeIETSFGFDTATKIYSE 229
|
170 180 190
....*....|....*....|....*....|.
gi 537995004 162 SLCEIAFDSVIYPiKSVTIVEIMGRDAGWLT 192
Cdd:cd00765 230 LIGNVMRDARSTG-KYWHFVKLMGRSASHIA 259
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
11-230 |
2.66e-05 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 46.35 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 11 GGPTVVINA-----TLAGVIQGalkadyEKIYGMINGIDGLLDEKMVDLSsFKDQKNLFKL--------IHTPAMYLGSC 77
Cdd:cd00764 398 GAPAAGMNAavrsaVRYGLAHG------HRPYAIYDGFEGLAKGQIVELG-WIDVGGWTGRggselgtkRTLPKKDLETI 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 78 RYKIfekdqsikqriitilNKYEITDFFYIGGNDSMDTIEKLS----TYAKVCncpINFIGIPKTIDNDLMNIDYTPGYP 153
Cdd:cd00764 471 AYNF---------------QKYGIDGLIIVGGFEAYKGLLQLReareQYEEFC---IPMVLIPATVSNNVPGTDFSLGSD 532
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 154 SACHYVATSlCEIAFDSVIYPIKSVTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDF---LEQIKDKLK 230
Cdd:cd00764 533 TALNALMKY-CDRIKQSASGTKRRVFIVETMGGYCGYLATMTGLAV-----GADAAYVFEEPFNIRDLqenVEHLTEKMK 606
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
36-192 |
3.82e-04 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 42.47 E-value: 3.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 36 IYGMINGIDGLLDEKMVDLSS-----FKDQKNlFKLIhtpamylGSCRYKIfEKDQSIKQRIITIlNKYEITDFFYIGGN 110
Cdd:PLN02251 131 LYGFKGGPAGIMKCKYVELTAefiypYRNQGG-FDMI-------CSGRDKI-ETPEQFKQAEETA-TKLDLDGLVVIGGD 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 111 DSMDTIEKLSTYAKVCNCPINFIGIPKTIDNDL--MNIDYTPGYPSACHYVATSLCEIAFDSVIYPiKSVTIVEIMGRDA 188
Cdd:PLN02251 201 DSNTNACLLAEYFRAKNLKTRVIGCPKTIDGDLksKEVPTSFGFDTACKIYSEMIGNVMIDARSTG-KYYHFVRLMGRAA 279
|
....
gi 537995004 189 GWLT 192
Cdd:PLN02251 280 SHIT 283
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
96-232 |
1.06e-03 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 41.17 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537995004 96 LNKYEITDFFYIGGNDSMDTIEKLST----YAKVCncpINFIGIPKTIDNDLMNIDYTPGYPSACHYVaTSLCEIAFDSV 171
Cdd:TIGR02478 474 FQQHKIDGLIIIGGFEAFEALYQLDAarekYPAFR---IPMVVIPATISNNVPGTEYSLGSDTALNEI-TEYCDNIKQSA 549
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 537995004 172 IYPIKSVTIVEIMGRDAGWLTASAQLVNevypdSIDLIYMPENIFDENDfLEQIKDKLKKK 232
Cdd:TIGR02478 550 SASKRRVFVVETMGGYSGYLATMAGLAT-----GADAAYIPEEGISLKD-LQEDIEHLKET 604
|
|
| |
