|
Name |
Accession |
Description |
Interval |
E-value |
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
2-420 |
0e+00 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 676.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 2 KNQPLAYRMRPTCLEEIVGQQHLVAPGKIIARMIAAKQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDTKKEL 81
Cdd:COG2256 11 ANAPLAERMRPRTLDEVVGQEHLLGPGKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANATDAEFVALSAVTSGVKDI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 82 QIVIEEAKM----SGTVILLLDEIHRLDKPKQDFLLPHLENGRVILIGATTENPYIAINPAIRSRTQIFELIPLTPEEIH 157
Cdd:COG2256 91 REVIEEARErrayGRRTILFVDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNSALLSRCRVFVLKPLSEEDLE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 158 QALNRALTDETKGLGQYDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPENEdrKIIITEEIAGNCLQRKVFAHDKN 237
Cdd:COG2256 171 QLLERALADDERGLGGYKLELDDEALEALARLADGDARRALNALELAVLSAPPDG--VIEITLELVEEALQRRALRYDKD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 238 GDQHYDVISAFQKSIRGSDVDAALHYMARLIEAGE-LITLIRRLLVIAYEDIGLANPAGASRAVLAVQAAEKLGLPEARI 316
Cdd:COG2256 249 GDEHYDLISAFIKSIRGSDPDAALYWLARMLEAGEdPRFIARRLVIMASEDIGLADPQALQIAVAAAQAVERLGMPEGRI 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 317 PLANAVIELALSPKSNTAILSIDAALSDVRQGKSGKIPSHLQDAHYQGAQKLGRGTNYQYPHNYPNHWVKQQYLPDTLKH 396
Cdd:COG2256 329 ALAQAVIYLATAPKSNAAYLAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPGGYVGQQYLPDELKG 408
|
410 420
....*....|....*....|....
gi 537925014 397 TQYFHPDPTsKFEEALKEQYKKFR 420
Cdd:COG2256 409 RRYYEPTER-GFERKIKERLEKLR 431
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
5-420 |
0e+00 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 665.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 5 PLAYRMRPTCLEEIVGQQHLVAPGKIIARMIAAKQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDTKKELQIV 84
Cdd:PRK13342 1 PLAERMRPKTLDEVVGQEHLLGPGKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGATDAPFEALSAVTSGVKDLREV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 85 IEEAK----MSGTVILLLDEIHRLDKPKQDFLLPHLENGRVILIGATTENPYIAINPAIRSRTQIFELIPLTPEEIHQAL 160
Cdd:PRK13342 81 IEEARqrrsAGRRTILFIDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNPALLSRAQVFELKPLSEEDIEQLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 161 NRALTDETKGLgqydVEVEDGAMHTFTHFSNGDVRSSLNALELAVKStpenedrKIIITEEIAGNCLQRKVFAHDKNGDQ 240
Cdd:PRK13342 161 KRALEDKERGL----VELDDEALDALARLANGDARRALNLLELAALG-------VDSITLELLEEALQKRAARYDKDGDE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 241 HYDVISAFQKSIRGSDVDAALHYMARLIEAGE-LITLIRRLLVIAYEDIGLANPAGASRAVLAVQAAEKLGLPEARIPLA 319
Cdd:PRK13342 230 HYDLISALHKSIRGSDPDAALYYLARMLEAGEdPLFIARRLVIIASEDIGLADPNALQVAVAAADAVERIGMPEGRIALA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 320 NAVIELALSPKSNTAILSIDAALSDVRQGKSGKIPSHLQDAHYQGAQKLGRGTNYQYPHNYPNHWVKQQYLPDTLKHTQY 399
Cdd:PRK13342 310 QAVIYLALAPKSNAAYTAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPNGYVGQQYLPDELKGKRY 389
|
410 420
....*....|....*....|.
gi 537925014 400 FHPdPTSKFEEALKEQYKKFR 420
Cdd:PRK13342 390 YEP-TERGFEKKIKERLEKLK 409
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
5-420 |
2.32e-153 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 451.05 E-value: 2.32e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 5 PLAYRMRPTCLEEIVGQQHLVAPGKIIARMIAAKQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDTKKELQIV 84
Cdd:PRK13341 17 PLADRLRPRTLEEFVGQDHILGEGRLLRRAIKADRVGSLILYGPPGVGKTTLARIIANHTRAHFSSLNAVLAGVKDLRAE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 85 IEEAKMS-----GTVILLLDEIHRLDKPKQDFLLPHLENGRVILIGATTENPYIAINPAIRSRTQIFELIPLTPEEIHQA 159
Cdd:PRK13341 97 VDRAKERlerhgKRTILFIDEVHRFNKAQQDALLPWVENGTITLIGATTENPYFEVNKALVSRSRLFRLKSLSDEDLHQL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 160 LNRALTDETKGLGQYDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPENEDRKIIITEEIAGNCLQRKVFAHDKNGD 239
Cdd:PRK13341 177 LKRALQDKERGYGDRKVDLEPEAEKHLVDVANGDARSLLNALELAVESTPPDEDGLIDITLAIAEESIQQRAVLYDKEGD 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 240 QHYDVISAFQKSIRGSDVDAALHYMARLIEAGELITLI-RRLLVIAYEDIGLANPAGASRAVLAVQAAEKLGLPEARIPL 318
Cdd:PRK13341 257 AHFDTISAFIKSLRGSDPDAALYWLARMVEAGEDPRFIfRRMLIAASEDVGLADPQALVVVEACAAAFERVGLPEGLYPL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 319 ANAVIELALSPKSNTAILSIDaALSDVRQGKSGKIPSHLQDAHYQGAqKLGRGTNYQYPHNYPNHWVKQQYLPDTLKHTQ 398
Cdd:PRK13341 337 AQAALYLATAPKSNSVLGFFD-ALKKVREEQVQDVPNHLRDANRDGK-AFGDGVGYRYPHAFRDHWVAQQYLPEALQGEV 414
|
410 420
....*....|....*....|..
gi 537925014 399 YFHPDPTSkFEEALKEQYKKFR 420
Cdd:PRK13341 415 FWQPSRQG-WEGERRERLARRR 435
|
|
| MgsA_C |
pfam12002 |
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA ... |
254-411 |
5.38e-90 |
|
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication. Additionally, MgsA may play a role in chromosomal segregation. This is consistent with a report that MgsA co-localizes with the replisome and affects chromosome segregation. This domain represents the C terminal region of MgsA.
Pssm-ID: 463426 [Multi-domain] Cd Length: 158 Bit Score: 269.21 E-value: 5.38e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 254 GSDVDAALHYMARLIEAGE-LITLIRRLLVIAYEDIGLANPAGASRAVLAVQAAEKLGLPEARIPLANAVIELALSPKSN 332
Cdd:pfam12002 1 GSDPDAALYWLARMLEAGEdPLFIARRLVIIASEDIGLADPQALVVAVAAAQAVERIGMPEARIPLAQAVIYLALAPKSN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 537925014 333 TAILSIDAALSDVRQGKSGKIPSHLQDAHYQGAQKLGRGTNYQYPHNYPNHWVKQQYLPDTLKHTQYFHPdPTSKFEEA 411
Cdd:pfam12002 81 SAYLAIDAALADVREGGSLPVPLHLRNAPTKLMKKLGYGKGYKYPHDYPNGYVKQQYLPDELKGRRYYEP-TDNGYEKK 158
|
|
| PRK14700 |
PRK14700 |
recombination factor protein RarA; Provisional |
113-415 |
3.31e-57 |
|
recombination factor protein RarA; Provisional
Pssm-ID: 173163 [Multi-domain] Cd Length: 300 Bit Score: 189.84 E-value: 3.31e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 113 LPHLENGRVILIGATTENPYIAINPAIRSRTQIFELIPLTPEEIHQALNRALT-DETkgLGQYDVEVEDGAMHTFTHFSN 191
Cdd:PRK14700 1 MPYVESGKIILIGATTENPTYYLNDALVSRLFILRLKRLSLVATQKLIEKALSqDEV--LAKHKFKIDDGLYNAMHNYNE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 192 GDVRSSLNALE-LAVKSTPENEdrkIIITEEIAGNCLQRKVFAHDKNGDQHYDVISAFQKSIRGSDVDAALHYMARLIEA 270
Cdd:PRK14700 79 GDCRKILNLLErMFLISTRGDE---IYLNKELFDQAVGETSRDFHREGKEFYEQLSAFHKSVRGTDPDAAIFWLSVMLDN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 271 G-ELITLIRRLLVIAYEDIGLANPAGASRAVLAVQAAEKLGLPEARIPLANAVIELALSPKSNTAILSIDAALSDVRQGK 349
Cdd:PRK14700 156 GvDPLVIARRMLCIASEDIGNADPQALRVAMDAWNAYEKLGMPEGRLVLAQAAIYLAVAPKSNACYKALAQAQQLVKSLG 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 537925014 350 SGKIPSHLQDAhyqgaqklgRGTNYQYPHNYPNHWVKQQYLPDTLKHTQYfhpDPTSK-FEEALKEQ 415
Cdd:PRK14700 236 NIDVPQHLKNY---------KDSNYLYPHNYPNSYVIQQYLPDNIIQNFY---QPTASgFEAKIKTK 290
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
172-253 |
4.93e-34 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 121.81 E-value: 4.93e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 172 GQYDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPENeDRKIIITEEIAGNCLQRKVFAHDKNGDQHYDVISAFQKS 251
Cdd:pfam16193 1 GGLKIELDDEALEALAELADGDARRALNALELAVLSTPPD-DGGIHITLEILEEALQRKALRYDKDGDEHYDLISAFHKS 79
|
..
gi 537925014 252 IR 253
Cdd:pfam16193 80 IR 81
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
151-228 |
4.42e-20 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 83.84 E-value: 4.42e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 537925014 151 LTPEEIHQALNRALTDETKGlGQYDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPenEDRKIIITEEIAGNCLQ 228
Cdd:cd18139 1 LSEEDLEKLLKRALEDKERG-GDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAE--EDGGIVITLEDLEEVLQ 75
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
43-151 |
6.47e-20 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 84.95 E-value: 6.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL----------- 104
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSElvskyvgESEKRLRELFEAAKKLAPCVIFIDEIDALagsrgsggdse 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 537925014 105 DKPKQDFLLPHLE-----NGRVILIGATTeNPYIaINPAIRSRTQIFELIPL 151
Cdd:pfam00004 81 SRRVVNQLLTELDgftssNSKVIVIAATN-RPDK-LDPALLGRFDRIIEFPL 130
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
12-285 |
6.15e-18 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 84.47 E-value: 6.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 12 PTCLEEIVGQQHLVapgKIIARMIAAKQLS-SMILYGPPGIGKTSIASAIAgttkyafRTLN------------------ 72
Cdd:COG2812 6 PQTFDDVVGQEHVV---RTLKNALASGRLAhAYLFTGPRGVGKTTLARILA-------KALNcengptgepcgecescra 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 73 --------------AATDTKKElQI--VIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLE--NGRVILIGATTEn 130
Cdd:COG2812 76 iaagshpdvieidaEASNIGVD-DIreLIEKVSYAPVEgrykVYIIDEAHMLTTEAFNALLKTLEepPPHVVFILATTE- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 131 PYiAINPAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRsslNALELAvkstpe 210
Cdd:COG2812 154 PQ-KLLPTILSRCQRFDFRRLPPEEIAEHLAKIAERE-------GIEIEPEALALIARAADGSMR---DALSLL------ 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 211 nedrkiiiTEEIAGNCLQRKvfahdkngDQHYDVISAfqksIRGSDVDAALHYMARLIEAG--------ELITLIRRLLV 282
Cdd:COG2812 217 --------DQAIAFGLLDRR--------ELLLDLLEA----LLAGDVAALLALAEELAKRGrdlkrfldDLLSLLRDLLL 276
|
...
gi 537925014 283 IAY 285
Cdd:COG2812 277 LKL 279
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
19-151 |
2.66e-17 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 78.34 E-value: 2.66e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 19 VGQQHLVapgKIIARMIAAKQLSSMILYGPPGIGKTSIASAIA---GTTKYAFRTLNAATDTKK----------ELQIVI 85
Cdd:cd00009 1 VGQEEAI---EALREALELPPPKNLLLYGPPGTGKTTLARAIAnelFRPGAPFLYLNASDLLEGlvvaelfghfLVRLLF 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 537925014 86 EEAKMSGTVILLLDEIHRLDKPKQDFLLPHLE--------NGRVILIGATTENPYIAINPAIRSRTQIFELIPL 151
Cdd:cd00009 78 ELAEKAKPGVLFIDEIDSLSRGAQNALLRVLEtlndlridRENVRVIGATNRPLLGDLDRALYDRLDIRIVIPL 151
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
11-272 |
7.75e-17 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 80.69 E-value: 7.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 11 RPTCLEEIVGQQHlvapgkIIARM---IAAKQLSSMILYGPPGIGKTSIASAIA----GTT-KYAFRTLNAAtdtkKELQ 82
Cdd:PRK00440 12 RPRTLDEIVGQEE------IVERLksyVKEKNMPHLLFAGPPGTGKTTAALALArelyGEDwRENFLELNAS----DERG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 83 I-VIEE-------AKMSGTV---ILLLDEIHRLDKPKQDFLLPHLE----NGRVILIGatteNpYIA-INPAIRSRTQIF 146
Cdd:PRK00440 82 IdVIRNkikefarTAPVGGApfkIIFLDEADNLTSDAQQALRRTMEmysqNTRFILSC----N-YSSkIIDPIQSRCAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 147 ELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELA--------------VKSTPENE 212
Cdd:PRK00440 157 RFSPLKKEAVAERLRYIAENE-------GIEITDDALEAIYYVSEGDMRKAINALQAAaatgkevteeavykITGTARPE 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 537925014 213 DRKIIITEEIAGNCLQ-RKV---FAHDKnGDQHYDVISAFQKSIRGSDVDAALhyMARLIEA-GE 272
Cdd:PRK00440 230 EIREMIELALNGDFTEaREKlrdLMIDY-GLSGEDIIKQIHREVWSLDIPEEL--KVELIDAiGE 291
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
1-283 |
3.56e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 77.17 E-value: 3.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 1 MKNQPLAYRMRPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILY-GPPGIGKTSIASAIAGT---------------- 63
Cdd:PRK14953 1 MMYIPFARKYRPKFFKEVIGQEIVV---RILKNAVKLQRVSHAYIFaGPRGTGKTTIARILAKVlnclnpqegepcgkce 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 64 -----TKYAFRTL-------NAATDTKKELQIVIEEAKMSGTV-ILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGATT 128
Cdd:PRK14953 78 ncveiDKGSFPDLieidaasNRGIDDIRALRDAVSYTPIKGKYkVYIIDEAHMLTKEAFNALLKTLEEppPRTIFILCTT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 129 EnpYIAINPAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKST 208
Cdd:PRK14953 158 E--YDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEE-------KIEYEEKALDLLAQASEGGMRDAASLLDQASTYG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 209 PENEDRKIIitEEIAGNCLQrkvfahdkngdqhyDVISAFQKSIRGSDVDAALHYMARLIEAG--------ELITLIRRL 280
Cdd:PRK14953 229 EGKVTIKVV--EEFLGIVSQ--------------ESVRKFLNLLLESDVDEAIKFLRTLEEKGynlnkfwkQLEEEIRNI 292
|
...
gi 537925014 281 LVI 283
Cdd:PRK14953 293 LLN 295
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
11-261 |
3.05e-14 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 74.19 E-value: 3.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 11 RPTCLEEIVGQQhlvapgKIIARMIA----------AKQLssmILYGPPGIGKTSIASAIAGTTKYAFRTLNaATD--TK 78
Cdd:PRK04195 9 RPKTLSDVVGNE------KAKEQLREwieswlkgkpKKAL---LLYGPPGVGKTSLAHALANDYGWEVIELN-ASDqrTA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 79 KELQIVIEEAKMSGTV------ILLLDE---IHrldkPKQDF-----LLPHLENGR--VILigaTTENPYiaiNPA---I 139
Cdd:PRK04195 79 DVIERVAGEAATSGSLfgarrkLILLDEvdgIH----GNEDRggaraILELIKKAKqpIIL---TANDPY---DPSlreL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 140 RSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPEnedrkiiIT 219
Cdd:PRK04195 149 RNACLMIEFKRLSTRSIVPVLKRICRKE-------GIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGK-------LT 214
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 537925014 220 EEIAGNCLQRkvfahdkngDQHYDVISAFQKSIRGSDVDAAL 261
Cdd:PRK04195 215 LEDVKTLGRR---------DREESIFDALDAVFKARNADQAL 247
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
43-177 |
9.78e-14 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 70.68 E-value: 9.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVIlLLDEIHRLDKPKQDF---- 111
Cdd:COG1223 38 ILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSligsylgETARNLRKLFDFARRAPCVI-FFDEFDAIAKDRGDQndvg 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 112 --------LLPHLE--NGRVILIGATteNPYIAINPAIRSRtqiFEL---IPL-TPEEIHQALNR--------------A 163
Cdd:COG1223 117 evkrvvnaLLQELDglPSGSVVIAAT--NHPELLDSALWRR---FDEvieFPLpDKEERKEILELnlkkfplpfeldlkK 191
|
170
....*....|....
gi 537925014 164 LTDETKGLGQYDVE 177
Cdd:COG1223 192 LAKKLEGLSGADIE 205
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
9-202 |
1.19e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 69.48 E-value: 1.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 9 RMRPTCLEEIVGQQHLVAPgkiIARMIAAKQLSSMILY-GPPGIGKTSIASAIAGTTK---------------YAFRT-- 70
Cdd:PRK14963 7 RARPITFDEVVGQEHVKEV---LLAALRQGRLGHAYLFsGPRGVGKTTTARLIAMAVNcsgedpkpcgecescLAVRRga 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 71 ------LNAAT----DTKKELQIVIEEAKMSGT-VILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGATTENPYIAinP 137
Cdd:PRK14963 84 hpdvleIDAASnnsvEDVRDLREKVLLAPLRGGrKVYILDEAHMMSKSAFNALLKTLEEppEHVIFILATTEPEKMP--P 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 537925014 138 AIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALE 202
Cdd:PRK14963 162 TILSRTQHFRFRRLTEEEIAGKLRRLLEAE-------GREAEPEALQLVARLADGAMRDAESLLE 219
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
10-125 |
5.42e-12 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 63.67 E-value: 5.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 10 MRPTCLEEIVGQQHLVAPGKIIARmiAAKQ----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAtdtkkelqiVI 85
Cdd:pfam05496 1 LRPRTLDEYIGQEKVKENLKIFIE--AAKQrgeaLDHVLLYGPPGLGKTTLANIIANEMGVNIRITSGP---------AI 69
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 537925014 86 EEA--------KMSGTVILLLDEIHRLDKPKQDFLLPHLENGRV-ILIG 125
Cdd:pfam05496 70 ERPgdlaailtNLEPGDVLFIDEIHRLNRAVEEILYPAMEDFRLdIVIG 118
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
43-206 |
1.16e-11 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 66.09 E-value: 1.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL----DKPKQDF 111
Cdd:COG0464 194 LLLYGPPGTGKTLLARALAGELGLPLIEVDLSDlvskyvgETEKNLREVFDKARGLAPCVLFIDEADALagkrGEVGDGV 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 112 -------LLPHLEN--GRVILIGATteNPYIAINPAIRSR-TQIFELIPLTPEEIHQALNRALTDetKGLGQyDVEVEDG 181
Cdd:COG0464 274 grrvvntLLTEMEElrSDVVVIAAT--NRPDLLDPALLRRfDEIIFFPLPDAEERLEIFRIHLRK--RPLDE-DVDLEEL 348
|
170 180
....*....|....*....|....*
gi 537925014 182 AMHTFtHFSNGDVRsslNALELAVK 206
Cdd:COG0464 349 AEATE-GLSGADIR---NVVRRAAL 369
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
7-218 |
1.37e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 65.67 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 7 AYRMRPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILY-GPPGIGKTSIASAIAGTTK------------YAFRTLNA 73
Cdd:PRK14970 8 ARKYRPQTFDDVVGQSHIT---NTLLNAIENNHLAQALLFcGPRGVGKTTCARILARKINqpgyddpnedfsFNIFELDA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 74 ATDTK-KELQIVIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGATTENPYIAinPAIRSRTQIF 146
Cdd:PRK14970 85 ASNNSvDDIRNLIDQVRIPPQTgkykIYIIDEVHMLSSAAFNAFLKTLEEppAHAIFILATTEKHKII--PTILSRCQIF 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 537925014 147 ELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPENEDRKIII 218
Cdd:PRK14970 163 DFKRITIKDIKEHLAGIAVKE-------GIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVT 227
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
11-291 |
4.35e-11 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 63.85 E-value: 4.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 11 RPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILYGPPGIGKTSIASAIAG-----TTKYAFRTLNAA---TDTKKEL- 81
Cdd:PRK12402 10 RPALLEDILGQDEVV---ERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARelygdPWENNFTEFNVAdffDQGKKYLv 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 82 ------------------------QIVIEEAKM---SGTV-ILLLDEIHRLDKPKQDFLL----PHLENGRVILigaTTE 129
Cdd:PRK12402 87 edprfahflgtdkrirsskidnfkHVLKEYASYrplSADYkTILLDNAEALREDAQQALRrimeQYSRTCRFII---ATR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 130 NPYiAINPAIRSRT-QIFeLIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKST 208
Cdd:PRK12402 164 QPS-KLIPPIRSRClPLF-FRAPTDDELVDVLESIAEAE-------GVDYDDDGLELIAYYAGGDLRKAILTLQTAALAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 209 PEnedrkiiITEEIAGNCLQRkvfahdkNGDQhyDVISAFQKSIRGSDVDAALHYMARLI-----EAGELITLIRRLLVI 283
Cdd:PRK12402 235 GE-------ITMEAAYEALGD-------VGTD--EVIESLLDAAEAGDFTDARKTLDDLLideglSGGEVLEELLRVARS 298
|
....*...
gi 537925014 284 AYEDIGLA 291
Cdd:PRK12402 299 RYRGDNLA 306
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
8-125 |
5.29e-11 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 63.23 E-value: 5.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 8 YRMRPTCLEEIVGQQHLVAPGKIiarMI-AAKQ----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAtdtkkelq 82
Cdd:PRK00080 17 RSLRPKSLDEFIGQEKVKENLKI---FIeAAKKrgeaLDHVLLYGPPGLGKTTLANIIANEMGVNIRITSGP-------- 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 537925014 83 iVIEEAK---------MSGTViLLLDEIHRLDKPKQDFLLPHLENGRV-ILIG 125
Cdd:PRK00080 86 -ALEKPGdlaailtnlEEGDV-LFIDEIHRLSPVVEEILYPAMEDFRLdIMIG 136
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
15-244 |
7.45e-11 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 62.70 E-value: 7.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 15 LEEIVGQQHLVAPGKIIARmiAAK----QLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNA-ATDTKKELqIVIEEAK 89
Cdd:TIGR00635 3 LAEFIGQEKVKEQLQLFIE--AAKmrqeALDHLLLYGPPGLGKTTLAHIIANEMGVNLKITSGpALEKPGDL-AAILTNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 90 MSGTViLLLDEIHRLDKPKQDFLLPHLE------------NGRVI--------LIGATTEnPYIAINPaIRSRTQIFELI 149
Cdd:TIGR00635 80 EEGDV-LFIDEIHRLSPAVEELLYPAMEdfrldivigkgpSARSVrldlppftLVGATTR-AGMLTSP-LRDRFGIILRL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 150 PL-TPEEIHQALNRAltdetkgLGQYDVEVEDGAMHTFTHFSNGDVRSSLNALElAVKSTPENEDRKiIITEEIAGNCLQ 228
Cdd:TIGR00635 157 EFyTVEELAEIVSRS-------AGLLNVEIEPEAALEIARRSRGTPRIANRLLR-RVRDFAQVRGQK-IINRDIALKALE 227
|
250
....*....|....*.
gi 537925014 229 rkVFAHDKNGDQHYDV 244
Cdd:TIGR00635 228 --MLMIDELGLDEIDR 241
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
1-202 |
1.01e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 63.68 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 1 MKNQPLA-YRM-RPTCLEEIVGQQHLVAPGKIIarmIAAKQLSSMILY-GPPGIGKTSIASAIAGTTKYAFRT------- 70
Cdd:PRK07133 1 MRMKYKAlYRKyRPKTFDDIVGQDHIVQTLKNI---IKSNKISHAYLFsGPRGTGKTSVAKIFANALNCSHKTdllepcq 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 71 --------------LNAATDTK-KELQIVIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGATTE 129
Cdd:PRK07133 78 ecienvnnsldiieMDAASNNGvDEIRELIENVKNLPTQskykIYIIDEVHMLSKSAFNALLKTLEEppKHVIFILATTE 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 537925014 130 NPYIAInpAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALE 202
Cdd:PRK07133 158 VHKIPL--TILSRVQRFNFRRISEDEIVSRLEFILEKE-------NISYEKNALKLIAKLSSGSLRDALSIAE 221
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
31-204 |
3.19e-10 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 60.76 E-value: 3.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 31 IARMIAAKQLS-SMILYGPPGIGKTSIASAIA--------------GTTKYA---------FRTLNAaTDTKKEL---QI 83
Cdd:COG0470 8 LLAAAESGRLPhALLLHGPPGIGKTTLALALArdllcenpeggkacGQCHSRlmaagnhpdLLELNP-EEKSDQIgidQI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 84 --VIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLE----NGRVILIgatTENPYiAINPAIRSRTQIFELIPLTP 153
Cdd:COG0470 87 reLGEFLSLTPLEggrkVVIIDEADAMNEAAANALLKTLEeppkNTPFILI---ANDPS-RLLPTIRSRCQVIRFRPPSE 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 537925014 154 EEIHQALNRALtdetkglgqydveVEDGAMHTFTHFSNGDVRSSLNALELA 204
Cdd:COG0470 163 EEALAWLREEG-------------VDEDALEAILRLAGGDPRAAINLLQAL 200
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
1-202 |
5.82e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 61.01 E-value: 5.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 1 MKNQPLAYRMRPTCLEEIVGQQHLVapgKIIARMIAAKQLS-SMILYGPPGIGKTSIASAIAGttkyAFRTLN------- 72
Cdd:PRK05896 1 MSEITFYRKYRPHNFKQIIGQELIK---KILVNAILNNKLThAYIFSGPRGIGKTSIAKIFAK----AINCLNpkdgdcc 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 73 ---------------------AATDTK-KELQIVIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLENG--RVILI 124
Cdd:PRK05896 74 nscsvcesintnqsvdiveldAASNNGvDEIRNIIDNINYLPTTfkykVYIIDEAHMLSTSAWNALLKTLEEPpkHVVFI 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 537925014 125 GATTEnpYIAINPAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALE 202
Cdd:PRK05896 154 FATTE--FQKIPLTIISRCQRYNFKKLNNSELQELLKSIAKKE-------KIKIEDNAIDKIADLADGSLRDGLSILD 222
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
1-201 |
7.17e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 60.85 E-value: 7.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 1 MKNQPLAYRMRPTCLEEIVGQQHLVApgkIIARMIAAKQLSSMILY-GPPGIGKTSIASAIAgttkyafRTLNAAT---- 75
Cdd:PRK14959 1 MSHASLTARYRPQTFAEVAGQETVKA---ILSRAAQENRVAPAYLFsGTRGVGKTTIARIFA-------KALNCETaptg 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 76 -------------------------------DTKKELQIVIEEAKMSGTV-ILLLDEIHRLDKPKQDFLLPHLEN--GRV 121
Cdd:PRK14959 71 epcntceqcrkvtqgmhvdvveidgasnrgiDDAKRLKEAIGYAPMEGRYkVFIIDEAHMLTREAFNALLKTLEEppARV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 122 ILIGATTENPYIAInpAIRSRTQIFELIPLTPEEIHQALnraltdeTKGLGQYDVEVEDGAMHTFTHFSNGDVRSSLNAL 201
Cdd:PRK14959 151 TFVLATTEPHKFPV--TIVSRCQHFTFTRLSEAGLEAHL-------TKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLL 221
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
1-217 |
7.44e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 60.21 E-value: 7.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 1 MKNQPLAYRMRPTCLEEIVGQQHLVApgKIIARMIAAKQLSSMILYGPPGIGKTSIASAIA-------GTTKYAFRT--- 70
Cdd:PRK14961 1 MNYQILARKWRPQYFRDIIGQKHIVT--AISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAkslncqnGITSNPCRKcii 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 71 --------------LNAATDTK----KELQIVIEEAKMSGTV-ILLLDEIHRLDKPKQDFLLPHLENG--RVILIGATTE 129
Cdd:PRK14961 79 ckeiekglcldlieIDAASRTKveemREILDNIYYSPSKSRFkVYLIDEVHMLSRHSFNALLKTLEEPpqHIKFILATTD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 130 NPYIAInpAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTP 209
Cdd:PRK14961 159 VEKIPK--TILSRCLQFKLKIISEEKIFNFLKYILIKE-------SIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGK 229
|
....*...
gi 537925014 210 ENEDRKII 217
Cdd:PRK14961 230 GNINIKNV 237
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
11-128 |
1.19e-09 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 59.32 E-value: 1.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 11 RPTCLEEIVGQQHLVAPGKIiarMI-AAKQ----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAtdtkkelqiVI 85
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKI---FIeAAKKrgeaLDHVLLYGPPGLGKTTLAHIIANEMGVNIRITSGP---------AI 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 537925014 86 EEAkmsGTV-----------ILLLDEIHRLDKPKQDFLLPHLENGR---VI-----------------LIGATT 128
Cdd:COG2255 91 EKP---GDLaailtnleegdVLFIDEIHRLSRVVEEILYPAMEDFRldiVIgkgpaarsirldlppftLVGATT 161
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
7-211 |
2.04e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 59.40 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 7 AYRMRPTCLEEIVGQQHLVAPGKiiaRMIAAKQLSSMILY-GPPGIGKTSIASAIAGTTK-------------------- 65
Cdd:PRK14971 8 ARKYRPSTFESVVGQEALTTTLK---NAIATNKLAHAYLFcGPRGVGKTTCARIFAKTINcqnltadgeacnecescvaf 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 66 -----YAFRTLNAATDTKKE-LQIVIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGATTENPYI 133
Cdd:PRK14971 85 neqrsYNIHELDAASNNSVDdIRNLIEQVRIPPQIgkykIYIIDEVHMLSQAAFNAFLKTLEEppSYAIFILATTEKHKI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 537925014 134 AinPAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVKSTPEN 211
Cdd:PRK14971 165 L--PTILSRCQIFDFNRIQVADIVNHLQYVASKE-------GITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGN 233
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
44-140 |
2.86e-09 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 55.76 E-value: 2.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 44 ILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLdKPKQDF----- 111
Cdd:cd19503 38 LLHGPPGTGKTLLARAVANEAGANFLSISGPSivskylgESEKNLREIFEEARSHAPSIIFIDEIDAL-APKREEdqrev 116
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 537925014 112 ----------LLPHLEN-GRVILIGATteNPYIAINPAIR 140
Cdd:cd19503 117 errvvaqlltLMDGMSSrGKVVVIAAT--NRPDAIDPALR 154
|
|
| RecA-like_CDC48_r1-like |
cd19519 |
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ... |
43-140 |
3.83e-09 |
|
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410927 [Multi-domain] Cd Length: 166 Bit Score: 55.52 E-value: 3.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNA-------ATDTKKELQIVIEEAKMSGTVILLLDEIHRLdKPKQDFLLPH 115
Cdd:cd19519 37 ILLYGPPGTGKTLIARAVANETGAFFFLINGpeimsklAGESESNLRKAFEEAEKNAPAIIFIDEIDAI-APKREKTHGE 115
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 537925014 116 LE----------------NGRVILIGATteNPYIAINPAIR 140
Cdd:cd19519 116 VErrivsqlltlmdglkqRAHVIVMAAT--NRPNSIDPALR 154
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
42-151 |
9.36e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.92 E-value: 9.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 42 SMILYGPPGIGKTSIASAIAG---TTKYAFRTLNA---------------------ATDTKKELQIVIEEAKMSGTVILL 97
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARelgPPGGGVIYIDGedileevldqllliivggkkaSGSGELRLRLALALARKLKPDVLI 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 537925014 98 LDEIHRLDKPKQDFLL----------PHLENGRVILIGATT-ENPYIAINPAIRSRTQIFELIPL 151
Cdd:smart00382 84 LDEITSLLDAEQEALLllleelrlllLLKSEKNLTVILTTNdEKDLGPALLRRRFDRRIVLLLIL 148
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
41-151 |
1.44e-08 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 53.44 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 41 SSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAA-------TDTKKELQIVIEEAKMSGTVILLLDEIHRL--------D 105
Cdd:cd19481 27 KGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSsllskyvGESEKNLRKIFERARRLAPCILFIDEIDAIgrkrdssgE 106
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 537925014 106 KPKQDFLLPHL--------ENGRVILIGATteNPYIAINPAIRSRTQIFELIPL 151
Cdd:cd19481 107 SGELRRVLNQLlteldgvnSRSKVLVIAAT--NRPDLLDPALLRPGRFDEVIEF 158
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
44-223 |
1.67e-08 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 55.78 E-value: 1.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 44 ILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEI-----HRLD------ 105
Cdd:COG1222 116 LLYGPPGTGKTLLAKAVAGELGAPFIRVRGSElvskyigEGARNVREVFELAREKAPSIIFIDEIdaiaaRRTDdgtsge 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 106 -KPKQDFLLPHLE----NGRVILIGATteNPYIAINPAIRsRTQIFE---LIPL-TPEEIHQALNRALTD-ETKGlgqyD 175
Cdd:COG1222 196 vQRTVNQLLAELDgfesRGDVLIIAAT--NRPDLLDPALL-RPGRFDrviEVPLpDEEAREEILKIHLRDmPLAD----D 268
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 537925014 176 VEVEDGAMHTfTHFSNGDVRSSLN-ALELAVKstpenEDRKIIITEEIA 223
Cdd:COG1222 269 VDLDKLAKLT-EGFSGADLKAIVTeAGMFAIR-----EGRDTVTMEDLE 311
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
44-161 |
2.98e-08 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 55.83 E-value: 2.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 44 ILYGPPGIGKTSIASAIA----------GTTKYAFRTLN-----AATDTKKE----LQIVIEEAKMSGTVILLLDEIHRL 104
Cdd:CHL00095 204 ILIGEPGVGKTAIAEGLAqrivnrdvpdILEDKLVITLDiglllAGTKYRGEfeerLKRIFDEIQENNNIILVIDEVHTL 283
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 537925014 105 --------DKPKQDFLLPHLENGRVILIGATTENPY---IAINPAIRSRTQIFELIPLTPEEIHQALN 161
Cdd:CHL00095 284 igagaaegAIDAANILKPALARGELQCIGATTLDEYrkhIEKDPALERRFQPVYVGEPSVEETIEILF 351
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1-349 |
7.87e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 54.43 E-value: 7.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 1 MKNQPLAYRMRPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILY-GPPGIGKTSIA---------------------- 57
Cdd:PRK14950 1 MTVQVLYRKWRSQTFAELVGQEHVV---QTLRNAIAEGRVAHAYLFtGPRGVGKTSTArilakavncttndpkgrpcgtc 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 58 ---SAIAGTTKYAFRTLNAATDTKKE-LQIVIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGAT 127
Cdd:PRK14950 78 emcRAIAEGSAVDVIEMDAASHTSVDdAREIIERVQFRPALarykVYIIDEVHMLSTAAFNALLKTLEEppPHAIFILAT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 128 TEnpYIAINPAIRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALE-LAVK 206
Cdd:PRK14950 158 TE--VHKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAE-------GINLEPGALEAIARAATGSMRDAENLLQqLATT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 207 STPEnedrkiiITEEIAGNCLqrkvfahdknGDQHYDVISAFQKSIRGSDVDAALHYMARLIEAGELITLIRRLLVIAYE 286
Cdd:PRK14950 229 YGGE-------ISLSQVQSLL----------GISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLR 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 287 DIGLANpAGASRAVLAVQAAEKLGL-----------------------------PEARIPLANAVIELALSPKSNTAILS 337
Cdd:PRK14950 292 QVMLLN-SGADRSLLDLTADEKAALqkvsqianlealtkwvkafsqldfqlrttSYGQLPLELAVIEALLVPVPAPQPAK 370
|
410
....*....|..
gi 537925014 338 IDAALSDVRQGK 349
Cdd:PRK14950 371 PTAAAPSPVRPT 382
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
43-140 |
1.24e-07 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 53.76 E-value: 1.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLdKPKQDFLLPH 115
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGPEimskyygESEERLREIFKEAEENAPSIIFIDEIDAI-APKREEVTGE 293
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 537925014 116 LEN----------------GRVILIGATteNPYIAINPAIR 140
Cdd:TIGR01243 294 VEKrvvaqlltlmdglkgrGRVIVIGAT--NRPDALDPALR 332
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
5-204 |
2.17e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 52.94 E-value: 2.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 5 PLAYRMRPTCLEEIVGQQHLVapgKIIARMIAAKQLS-SMILYGPPGIGKTSIASAIAG--------TTKYAFRT----- 70
Cdd:PRK06645 10 PFARKYRPSNFAELQGQEVLV---KVLSYTILNDRLAgGYLLTGIRGVGKTTSARIIAKavncsaliTENTTIKTceqct 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 71 ---------------LNAATDTK-KELQIVIEEAK----MSGTVILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGATT 128
Cdd:PRK06645 87 ncisfnnhnhpdiieIDAASKTSvDDIRRIIESAEykplQGKHKIFIIDEVHMLSKGAFNALLKTLEEppPHIIFIFATT 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 537925014 129 ENPYIainPA-IRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELA 204
Cdd:PRK06645 167 EVQKI---PAtIISRCQRYDLRRLSFEEIFKLLEYITKQE-------NLKTDIEALRIIAYKSEGSARDAVSILDQA 233
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
43-140 |
2.98e-07 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 50.10 E-value: 2.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLdKPKQDF---- 111
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGELKVPFLKISATEivsgvsgESEEKIRELFDQAISNAPCIVFIDEIDAI-TPKRESaqre 115
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 537925014 112 --------LLPHLEN--------GRVILIGATTENPyiAINPAIR 140
Cdd:cd19518 116 merrivsqLLTCMDElnnektagGPVLVIGATNRPD--SLDPALR 158
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
5-202 |
4.87e-07 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 51.27 E-value: 4.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 5 PLAYRMRPTCLEEIVGQQHLVAPGKIIARmiaAKQLSSMILYGPPGIGKTSIASAIA----GTT-KYAFRTLNAATDtkK 79
Cdd:PLN03025 2 PWVEKYRPTKLDDIVGNEDAVSRLQVIAR---DGNMPNLILSGPPGTGKTTSILALAhellGPNyKEAVLELNASDD--R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 80 ELQIVIEEAKMSG----------TVILLLDEIHRLDKPKQDFLLPHLEngrviLIGATTE-----NPYIAINPAIRSRTQ 144
Cdd:PLN03025 77 GIDVVRNKIKMFAqkkvtlppgrHKIVILDEADSMTSGAQQALRRTME-----IYSNTTRfalacNTSSKIIEPIQSRCA 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 537925014 145 IFELIPLTPEEIhqaLNRALtdetKGLGQYDVEVEDGAMHTFTHFSNGDVRSSLNALE 202
Cdd:PLN03025 152 IVRFSRLSDQEI---LGRLM----KVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQ 202
|
|
| RecA-like_Yta7-like |
cd19517 |
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ... |
44-140 |
8.40e-07 |
|
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410925 [Multi-domain] Cd Length: 170 Bit Score: 48.66 E-value: 8.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 44 ILYGPPGIGKTSIASAIA-----GTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL---DKPK 108
Cdd:cd19517 38 LFHGPPGTGKTLMARALAaecskGGQKVSFFMRKGADclskwvgEAERQLRLLFEEAYRMQPSIIFFDEIDGLapvRSSK 117
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 537925014 109 QD-----------FLLPHLEN-GRVILIGATteNPYIAINPAIR 140
Cdd:cd19517 118 QEqihasivstllALMDGLDNrGQVVVIGAT--NRPDALDPALR 159
|
|
| RecA-like_VPS4-like |
cd19509 |
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ... |
41-127 |
1.06e-06 |
|
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410917 [Multi-domain] Cd Length: 163 Bit Score: 48.50 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 41 SSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL--------- 104
Cdd:cd19509 33 RGILLYGPPGTGKTLLARAVASESGSTFFSISASSlvskwvgESEKIVRALFALARELQPSIIFIDEIDSLlsergsgeh 112
|
90 100 110
....*....|....*....|....*....|.
gi 537925014 105 ---DKPKQDFL-----LPHLENGRVILIGAT 127
Cdd:cd19509 113 easRRVKTEFLvqmdgVLNKPEDRVLVLGAT 143
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
42-142 |
2.40e-06 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 46.52 E-value: 2.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 42 SMILYGPPGIGKTSIASAIA---GTTKYAFRTLNAAT--------------DTKKELQIVIEEAKMSGtvILLLDEIHRL 104
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAaalSNRPVFYVQLTRDTteedlfgrrnidpgGASWVDGPLVRAAREGE--IAVLDEINRA 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 537925014 105 DKPKQDFLLPHLENGR----------------VILIGATTENPYIA--INPAIRSR 142
Cdd:pfam07728 79 NPDVLNSLLSLLDERRlllpdggelvkaapdgFRLIATMNPLDRGLneLSPALRSR 134
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
44-139 |
3.31e-06 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 46.89 E-value: 3.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 44 ILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLDKPK-------- 108
Cdd:cd19511 31 LLYGPPGCGKTLLAKALASEAGLNFISVKGPElfskyvgESERAVREIFQKARQAAPCIIFFDEIDSLAPRRgqsdssgv 110
|
90 100 110
....*....|....*....|....*....|....*...
gi 537925014 109 QDFLLPHL-------ENGRVILIGATTENPYIaINPAI 139
Cdd:cd19511 111 TDRVVSQLlteldgiESLKGVVVIAATNRPDM-IDPAL 147
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
34-201 |
3.94e-06 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 49.07 E-value: 3.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 34 MIAAKQLSSMILYGPPGIGKTSIASAIA----GTTKYAFRTLNAATDTKKELQIVIE-EAKMSGTV------ILLLDEIH 102
Cdd:TIGR03922 306 LPVAQTSNHMLFAGPPGTGKTTIARVVAkiycGLGVLRKPLVREVSRADLIGQYIGEsEAKTNEIIdsalggVLFLDEAY 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 103 RL----DKPKQDF-------LLPHLENGR--VILIGATTEN---PYIAINPAIRSR-TQIFELIPLTPEEIhQALNRALT 165
Cdd:TIGR03922 386 TLvetgYGQKDPFgleaidtLLARMENDRdrLVVIGAGYRKdldKFLEVNEGLRSRfTRVIEFPSYSPDEL-VEIARRMA 464
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 537925014 166 DETKGLgqYDVEVEDGAMHTFTHFS-------NGDVRSSLNAL 201
Cdd:TIGR03922 465 TERDSV--LDDAAADALLEAATTLAqdttpdaNGDLRRGLDIA 505
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
9-155 |
4.16e-05 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 45.37 E-value: 4.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 9 RMRPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILYGP-PGIGKTSIASAIAGTTKYAFRTLNAATDtkkELQIVIEE 87
Cdd:PHA02544 14 KYRPSTIDECILPAADK---ETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEVGAEVLFVNGSDC---RIDFVRNR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 88 AK-----MS---GTVILLLDEIHRLDKPK-QDFLLPHLE----NGRVILigatTENPYIAINPAIRSRTQIFELIPLTPE 154
Cdd:PHA02544 88 LTrfastVSltgGGKVIIIDEFDRLGLADaQRHLRSFMEayskNCSFII----TANNKNGIIEPLRSRCRVIDFGVPTKE 163
|
.
gi 537925014 155 E 155
Cdd:PHA02544 164 E 164
|
|
| hflB |
PRK10733 |
ATP-dependent zinc metalloprotease FtsH; |
22-101 |
8.95e-05 |
|
ATP-dependent zinc metalloprotease FtsH;
Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 44.64 E-value: 8.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 22 QHLVAPGKIiaRMIAAKQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDTK-------KELQIVIEEAKMSGTV 94
Cdd:PRK10733 169 EYLREPSRF--QKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEmfvgvgaSRVRDMFEQAKKAAPC 246
|
....*..
gi 537925014 95 ILLLDEI 101
Cdd:PRK10733 247 IIFIDEI 253
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
15-101 |
3.65e-04 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 41.06 E-value: 3.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 15 LEEIVgqQHLVAPGKIiaRMIAAKQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDTK-------KELQIVIEE 87
Cdd:cd19501 16 LKEVV--EFLKNPEKF--TKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEmfvgvgaSRVRDLFEQ 91
|
90
....*....|....
gi 537925014 88 AKMSGTVILLLDEI 101
Cdd:cd19501 92 AKKNAPCIVFIDEI 105
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
43-210 |
4.40e-04 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 42.59 E-value: 4.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEI--------HRLDKP 107
Cdd:TIGR01243 490 VLLFGPPGTGKTLLAKAVATESGANFIAVRGPEilskwvgESEKAIREIFRKARQAAPAIIFFDEIdaiapargARFDTS 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 108 KQDFLLPHL--------ENGRVILIGATTEnPYIaINPAIRsRTQIFELIPLTPEEIHQALNRALTDETKG--LGQyDVE 177
Cdd:TIGR01243 570 VTDRIVNQLltemdgiqELSNVVVIAATNR-PDI-LDPALL-RPGRFDRLILVPPPDEEARKEIFKIHTRSmpLAE-DVD 645
|
170 180 190
....*....|....*....|....*....|....*...
gi 537925014 178 VEDGAMHTfTHFSNGDV-----RSSLNALELAVKSTPE 210
Cdd:TIGR01243 646 LEELAEMT-EGYTGADIeavcrEAAMAALRESIGSPAK 682
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
43-139 |
5.90e-04 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 40.16 E-value: 5.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLdKPKQDF---- 111
Cdd:cd19530 33 VLLYGPPGCGKTLLAKAVANESGANFISVKGPEllnkyvgESERAVRQVFQRARASAPCVIFFDEVDAL-VPKRGDggsw 111
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 537925014 112 --------LLPHLENG----RVILIGATTEnPYIaINPAI 139
Cdd:cd19530 112 aservvnqLLTEMDGLeersNVFVIAATNR-PDI-IDPAM 149
|
|
| RecA-like_VCP_r2 |
cd19529 |
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
33-139 |
6.16e-04 |
|
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 40.17 E-value: 6.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 33 RMIAAKQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLd 105
Cdd:cd19529 20 KRLGIRPPKGILLYGPPGTGKTLLAKAVATESNANFISVKGPEllskwvgESEKAIREIFRKARQVAPCVIFFDEIDSI- 98
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 537925014 106 KPKQ-------------DFLLPHL----ENGRVILIGATTEnPYIaINPAI 139
Cdd:cd19529 99 APRRgttgdsgvtervvNQLLTELdgleEMNGVVVIAATNR-PDI-IDPAL 147
|
|
| RecA-like_VPS4 |
cd19521 |
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ... |
38-142 |
7.19e-04 |
|
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410929 [Multi-domain] Cd Length: 170 Bit Score: 40.23 E-value: 7.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 38 KQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLDKP--- 107
Cdd:cd19521 38 KPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDlvskwmgESEKLVKQLFAMARENKPSIIFIDEVDSLCGTrge 117
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 537925014 108 ---------KQDFLLPH----LENGRVILIGATTeNPYIaINPAIRSR 142
Cdd:cd19521 118 geseasrriKTELLVQMngvgNDSQGVLVLGATN-IPWQ-LDSAIRRR 163
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
29-170 |
7.51e-04 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 41.09 E-value: 7.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 29 KIIARMIAAKQLSSM-ILYGPPGIGKTSIASAIAG--------------TTKYAFRTL------NAATDTKKELQIVIEE 87
Cdd:COG2842 38 RFAEALDEARALPGIgVVYGESGVGKTTAAREYANrnpnviyvtaspswTSKELLEELaeelgiPAPPGTIADLRDRILE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 88 aKMSGTVILL-LDEIHRLDKPKQDFLlphlengR---------VILIGatteNPYIAINpaIRSRTQIF-------ELIP 150
Cdd:COG2842 118 -RLAGTGRLLiIDEADHLKPKALEEL-------RdihdetgvgVVLIG----MERLPAK--LKRYEQLYsrigfwvEFKP 183
|
170 180 190
....*....|....*....|....*....|.
gi 537925014 151 LTPEEIH-----------QALNRALTDETKG 170
Cdd:COG2842 184 LSLEDVRalaeawgeltdPDLLELLHRITRG 214
|
|
| RecA-like_BCS1 |
cd19510 |
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ... |
44-101 |
7.88e-04 |
|
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410918 [Multi-domain] Cd Length: 153 Bit Score: 39.64 E-value: 7.88e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 537925014 44 ILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT--DTKKELQIVIEEA-KMSgtvILLLDEI 101
Cdd:cd19510 27 LLYGPPGTGKSSFIAALAGELDYDICDLNLSEvvLTDDRLNHLLNTApKQS---IILLEDI 84
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
8-283 |
8.15e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 41.78 E-value: 8.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 8 YRM-RPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILY-GPPGIGKTSIASAIAgttkyafRTLN------------- 72
Cdd:PRK05563 7 YRKwRPQTFEDVVGQEHIT---KTLKNAIKQGKISHAYLFsGPRGTGKTSAAKIFA-------KAVNclnppdgepcnec 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 73 ------------------AATDTK-KELQIVIEEAKMSGTV----ILLLDEIHRLDKPKQDFLLPHLEN--GRVILIGAT 127
Cdd:PRK05563 77 eickaitngslmdvieidAASNNGvDEIRDIRDKVKYAPSEakykVYIIDEVHMLSTGAFNALLKTLEEppAHVIFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 128 TENPYIainPA-IRSRTQIFELIPLTPEEIHQALNRALTDEtkglgqyDVEVEDGAMHTFTHFSNGDVRSSLNALELAVk 206
Cdd:PRK05563 157 TEPHKI---PAtILSRCQRFDFKRISVEDIVERLKYILDKE-------GIEYEDEALRLIARAAEGGMRDALSILDQAI- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 207 STPENEdrkiiITEEIAGNCLqrkvfahdknGDQHYDVISAFQKSIRGSDVDAALHYMARLIEAG--------ELITLIR 278
Cdd:PRK05563 226 SFGDGK-----VTYEDALEVT----------GSVSQEALDDLVDAIVEGDVAKALKILEELLDEGkdpnrfieDLIYYLR 290
|
....*
gi 537925014 279 RLLVI 283
Cdd:PRK05563 291 DLLLV 295
|
|
| RecA-like_Figl-1 |
cd19525 |
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ... |
43-144 |
9.62e-04 |
|
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410933 [Multi-domain] Cd Length: 186 Bit Score: 39.97 E-value: 9.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDT-------KKELQIVIEEAKMSGTVILLLDEIHRL----------- 104
Cdd:cd19525 58 ILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTskwvgegEKMVRALFSVARCKQPAVIFIDEIDSLlsqrgegehes 137
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 537925014 105 -DKPKQDFLLpHLE------NGRVILIGATteNPYIAINPAIRSRTQ 144
Cdd:cd19525 138 sRRIKTEFLV-QLDgattssEDRILVVGAT--NRPQEIDEAARRRLV 181
|
|
| RecA-like_KTNA1 |
cd19522 |
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ... |
43-104 |
1.17e-03 |
|
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410930 [Multi-domain] Cd Length: 170 Bit Score: 39.58 E-value: 1.17e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL 104
Cdd:cd19522 36 VLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTltskyrgESEKLVRLLFEMARFYAPTTIFIDEIDSI 104
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
15-62 |
1.39e-03 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 39.83 E-value: 1.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 537925014 15 LEEIVGQQHlvapgkiiAR---MIAAKQLSSMILYGPPGIGKTSIASAIAG 62
Cdd:pfam01078 2 LADVKGQEQ--------AKralEIAAAGGHNLLMIGPPGSGKTMLAKRLPG 44
|
|
| RecA-like_PEX1_r2 |
cd19526 |
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ... |
41-100 |
1.55e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410934 [Multi-domain] Cd Length: 158 Bit Score: 38.95 E-value: 1.55e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 537925014 41 SSMILYGPPGIGKTSIASAIAGTTKYAF------RTLNAATDTKKE-LQIVIEEAKMSGTVILLLDE 100
Cdd:cd19526 28 SGILLYGPPGCGKTLLASAIASECGLNFisvkgpELLNKYIGASEQnVRDLFSRAQSAKPCILFFDE 94
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
4-53 |
1.68e-03 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 40.59 E-value: 1.68e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 537925014 4 QPLAYRMRPTCLEEIVGQQHLVapgKIIARMIAAKQLSSMILYGPPGIGK 53
Cdd:PRK04132 7 KPWVEKYRPQRLDDIVGQEHIV---KRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| RecA-like_spastin |
cd19524 |
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ... |
43-127 |
2.82e-03 |
|
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410932 [Multi-domain] Cd Length: 164 Bit Score: 38.29 E-value: 2.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL----------- 104
Cdd:cd19524 36 LLLFGPPGNGKTMLAKAVAAESNATFFNISAASltskyvgEGEKLVRALFAVARELQPSIIFIDEVDSLlsersegehea 115
|
90 100
....*....|....*....|....*....
gi 537925014 105 -DKPKQDFL-----LPHLENGRVILIGAT 127
Cdd:cd19524 116 sRRLKTEFLiefdgVQSNGDDRVLVMGAT 144
|
|
| RecA-like_Lon |
cd19500 |
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ... |
35-61 |
3.18e-03 |
|
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410908 [Multi-domain] Cd Length: 182 Bit Score: 38.31 E-value: 3.18e-03
10 20 30
....*....|....*....|....*....|...
gi 537925014 35 IAAKQLSSMI------LYGPPGIGKTSIASAIA 61
Cdd:cd19500 26 LAVRKLKGSMkgpilcLVGPPGVGKTSLGKSIA 58
|
|
| PRK12422 |
PRK12422 |
chromosomal replication initiator protein DnaA; |
45-206 |
3.42e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 183521 [Multi-domain] Cd Length: 445 Bit Score: 39.43 E-value: 3.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 45 LYGPPGIGKTSIASAIAGTTKYA-FRTLNAATDTKKE-LQIVIEEAKMS-------GTVILLLDEIHRLDKP---KQDFL 112
Cdd:PRK12422 146 LFGPEGSGKTHLMQAAVHALRESgGKILYVRSELFTEhLVSAIRSGEMQrfrqfyrNVDALFIEDIEVFSGKgatQEEFF 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 113 LP----HLENGRVILIGATTENPYIAINPAIRSRtqiFE------LIPLTPEEIHQALNRaltdETKglgQYDVEVEDGA 182
Cdd:PRK12422 226 HTfnslHTEGKLIVISSTCAPQDLKAMEERLISR---FEwgiaipLHPLTKEGLRSFLER----KAE---ALSIRIEETA 295
|
170 180
....*....|....*....|....
gi 537925014 183 MHTFTHFSNGDVRSSLNALELAVK 206
Cdd:PRK12422 296 LDFLIEALSSNVKSLLHALTLLAK 319
|
|
| RecA-like_PEX6_r2 |
cd19527 |
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ... |
38-104 |
3.92e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410935 [Multi-domain] Cd Length: 160 Bit Score: 37.88 E-value: 3.92e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 537925014 38 KQLSSMILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRL 104
Cdd:cd19527 24 RKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPElinmyigESEANVREVFQKARDAKPCVIFFDELDSL 97
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
43-108 |
4.20e-03 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 37.87 E-value: 4.20e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 537925014 43 MILYGPPGIGKTSIASAIAGTTKYAFRTLNAAT-------DTKKELQIVIEEAKMSGTVILLLDEIHRLDKPK 108
Cdd:cd19528 30 VLFYGPPGCGKTLLAKAIANECQANFISVKGPElltmwfgESEANVRDIFDKARAAAPCVLFFDELDSIAKAR 102
|
|
| RecA-like_PAN_like |
cd19502 |
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ... |
44-101 |
4.32e-03 |
|
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410910 [Multi-domain] Cd Length: 171 Bit Score: 37.70 E-value: 4.32e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 537925014 44 ILYGPPGIGKTSIASAIAGTTKYAFRTLNAATDTKKEL-------QIVIEEAKMSGTVILLLDEI 101
Cdd:cd19502 41 LLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIgegarlvRELFEMAREKAPSIIFIDEI 105
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
16-120 |
5.28e-03 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 37.54 E-value: 5.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 537925014 16 EEIVGQQHLVAPgkiIARMIAA---------KQLSSMILYGPPGIGKTSIASAIAGT---TKYAFRTLN---------AA 74
Cdd:cd19499 11 ERVVGQDEAVKA---VSDAIRRaraglsdpnRPIGSFLFLGPTGVGKTELAKALAELlfgDEDNLIRIDmseymekhsVS 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 537925014 75 TDT--------KKELQIVIEEAKMSGTVILLLDEIHRLDKPKQDFLLPHLENGR 120
Cdd:cd19499 88 RLIgappgyvgYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGR 141
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
45-68 |
8.16e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 38.27 E-value: 8.16e-03
10 20
....*....|....*....|....
gi 537925014 45 LYGPPGIGKTSIASAIAGTTKYAF 68
Cdd:PRK03992 170 LYGPPGTGKTLLAKAVAHETNATF 193
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