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Conserved domains on  [gi|527035752|ref|WP_020882635|]
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MULTISPECIES: autotransporter domain-containing protein [Enterobacter]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhjY super family cl44262
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
 80-232 9.04e-11

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


The actual alignment was detected with superfamily member COG5571:

Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 61.05  E-value: 9.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752  80 PSGSTPAGAMSVGWNIPVsGRITTGPVMAWRY-----DGTApmminEFGDSATTQGLTDPLWHASVSTLGWRVDTQY-GE 153
Cdd:COG5571  489 TDGSQWGARLTAGYDFTA-GRLRTGPFAGLDYqkvkvDGYT-----ETGAGSTALSFGDQDRDSLVGSLGWRADYQLlGR 562

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752 154 LRPWAQISYNQQFGENQWKS-------QFGMPQTPAPTQSGNWMDVTVGTDIPFNTHMAAYASL----AQGEYTTTGeef 222
Cdd:COG5571  563 FNPYAEVAYEHEFGDDDRDVtaglaslPAGSFSLPAAAPDKNWGRATLGASAALTNGVSLFAGYsgtfGRDDGRQTS--- 639

                        170
                 ....*....|
gi 527035752 223 mYTLGVSANF 232
Cdd:COG5571  640 -VNLGLSARF 648
 
Name Accession Description Interval E-value
YhjY COG5571
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
 80-232 9.04e-11

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 61.05  E-value: 9.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752  80 PSGSTPAGAMSVGWNIPVsGRITTGPVMAWRY-----DGTApmminEFGDSATTQGLTDPLWHASVSTLGWRVDTQY-GE 153
Cdd:COG5571  489 TDGSQWGARLTAGYDFTA-GRLRTGPFAGLDYqkvkvDGYT-----ETGAGSTALSFGDQDRDSLVGSLGWRADYQLlGR 562

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752 154 LRPWAQISYNQQFGENQWKS-------QFGMPQTPAPTQSGNWMDVTVGTDIPFNTHMAAYASL----AQGEYTTTGeef 222
Cdd:COG5571  563 FNPYAEVAYEHEFGDDDRDVtaglaslPAGSFSLPAAAPDKNWGRATLGASAALTNGVSLFAGYsgtfGRDDGRQTS--- 639

                        170
                 ....*....|
gi 527035752 223 mYTLGVSANF 232
Cdd:COG5571  640 -VNLGLSARF 648
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 81-209 6.00e-04

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 40.06  E-value: 6.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752   81 SGSTPAGAMSVGWNIPVSGRITTGPVMAWRYDGTApmmINEFGDSATTQGLTDPL--WHASVSTLGWRVDTQY----GEL 154
Cdd:pfam03797 114 DGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLR---LDGFTESGGAAALSVDSqsYDSLTGRLGLRLSYTFdlggGTL 190

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 527035752  155 RPWAQISYNQQFGENQ--------WKSQFGMPQTPAPTQSGNWMDVTVGTDIPFNTHMAAYAS 209
Cdd:pfam03797 191 TPYARLGWRHEFGDDDpvttaafaGLSGAGSFTVAGADLARDSLELGAGLSAQLSDNLSLYAN 253
 
Name Accession Description Interval E-value
YhjY COG5571
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
 80-232 9.04e-11

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 61.05  E-value: 9.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752  80 PSGSTPAGAMSVGWNIPVsGRITTGPVMAWRY-----DGTApmminEFGDSATTQGLTDPLWHASVSTLGWRVDTQY-GE 153
Cdd:COG5571  489 TDGSQWGARLTAGYDFTA-GRLRTGPFAGLDYqkvkvDGYT-----ETGAGSTALSFGDQDRDSLVGSLGWRADYQLlGR 562

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752 154 LRPWAQISYNQQFGENQWKS-------QFGMPQTPAPTQSGNWMDVTVGTDIPFNTHMAAYASL----AQGEYTTTGeef 222
Cdd:COG5571  563 FNPYAEVAYEHEFGDDDRDVtaglaslPAGSFSLPAAAPDKNWGRATLGASAALTNGVSLFAGYsgtfGRDDGRQTS--- 639

                        170
                 ....*....|
gi 527035752 223 mYTLGVSANF 232
Cdd:COG5571  640 -VNLGLSARF 648
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 81-209 6.00e-04

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 40.06  E-value: 6.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527035752   81 SGSTPAGAMSVGWNIPVSGRITTGPVMAWRYDGTApmmINEFGDSATTQGLTDPL--WHASVSTLGWRVDTQY----GEL 154
Cdd:pfam03797 114 DGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLR---LDGFTESGGAAALSVDSqsYDSLTGRLGLRLSYTFdlggGTL 190

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 527035752  155 RPWAQISYNQQFGENQ--------WKSQFGMPQTPAPTQSGNWMDVTVGTDIPFNTHMAAYAS 209
Cdd:pfam03797 191 TPYARLGWRHEFGDDDpvttaafaGLSGAGSFTVAGADLARDSLELGAGLSAQLSDNLSLYAN 253
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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