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Conserved domains on  [gi|521983411|ref|WP_020494682|]
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nitroreductase family deazaflavin-dependent oxidoreductase [Sciscionella marina]

Protein Classification

nitroreductase family deazaflavin-dependent oxidoreductase( domain architecture ID 10513519)

nitroreductase family deazaflavin-dependent oxidoreductase similar to Mycobacterium tuberculosis deazaflavin-dependent nitroreductase and F420H(2)-dependent quinone reductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
F420H2_quin_red pfam04075
F420H(2)-dependent quinone reductase; This family of proteins is found in the genera ...
 9-139 2.93e-39

F420H(2)-dependent quinone reductase; This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.


:

Pssm-ID: 281995  Cd Length: 129  Bit Score: 128.72  E-value: 2.93e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521983411    9 LRTHQRIYEKTGGALGHRLLGMPTLLLRTIGRRSGQARTSALVYAREDDAYLVVASDGGARTSPAWLHNLRAEPECEIQI 88
Cdd:pfam04075   2 YREHVARYRRTGGTVGRRLPGVPVLLLTTTGRKTGQPRTTPLGGVRDGDSYLVVASKGGAPRHPGWYYNLKANPRVRVQI 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 521983411   89 GRRRRPATAEIVSrdDDRHAALLAKCDAVNRGrYSAYQHRTERPIPIVVLT 139
Cdd:pfam04075  82 GGRWLDGTARLAP--DDERARLWQLPVLNSPG-YAVYQSGTDRPIPVVVLT 129
 
Name Accession Description Interval E-value
F420H2_quin_red pfam04075
F420H(2)-dependent quinone reductase; This family of proteins is found in the genera ...
 9-139 2.93e-39

F420H(2)-dependent quinone reductase; This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.


Pssm-ID: 281995  Cd Length: 129  Bit Score: 128.72  E-value: 2.93e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521983411    9 LRTHQRIYEKTGGALGHRLLGMPTLLLRTIGRRSGQARTSALVYAREDDAYLVVASDGGARTSPAWLHNLRAEPECEIQI 88
Cdd:pfam04075   2 YREHVARYRRTGGTVGRRLPGVPVLLLTTTGRKTGQPRTTPLGGVRDGDSYLVVASKGGAPRHPGWYYNLKANPRVRVQI 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 521983411   89 GRRRRPATAEIVSrdDDRHAALLAKCDAVNRGrYSAYQHRTERPIPIVVLT 139
Cdd:pfam04075  82 GGRWLDGTARLAP--DDERARLWQLPVLNSPG-YAVYQSGTDRPIPVVVLT 129
hi_GC_TIGR00026 TIGR00026
deazaflavin-dependent oxidoreductase, nitroreductase family; This model represents a family of ...
 24-139 9.10e-30

deazaflavin-dependent oxidoreductase, nitroreductase family; This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 211538  Cd Length: 113  Bit Score: 104.03  E-value: 9.10e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521983411   24 GHRLLGMPTLLLRTIGRRSGQARTSALVYAREDDAYLVVASDGGARTSPAWLHNLRAEPECEIQIGRRRRPATAEIVSRD 103
Cdd:TIGR00026   1 GGIARGLPVLLLTTTGRKTGKPRTTPVYYVRHDPGVLVVASNGGAPRHPDWYKNLKANPRVRVRVGGKVFVATARLVSGD 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 521983411  104 DDRHaaLLAKCDAVNrGRYSAYQHRTERPIPIVVLT 139
Cdd:TIGR00026  81 ERAQ--LWAGVVRLY-PRYQRYQSRTDRPIPVVVLT 113
 
Name Accession Description Interval E-value
F420H2_quin_red pfam04075
F420H(2)-dependent quinone reductase; This family of proteins is found in the genera ...
 9-139 2.93e-39

F420H(2)-dependent quinone reductase; This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.


Pssm-ID: 281995  Cd Length: 129  Bit Score: 128.72  E-value: 2.93e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521983411    9 LRTHQRIYEKTGGALGHRLLGMPTLLLRTIGRRSGQARTSALVYAREDDAYLVVASDGGARTSPAWLHNLRAEPECEIQI 88
Cdd:pfam04075   2 YREHVARYRRTGGTVGRRLPGVPVLLLTTTGRKTGQPRTTPLGGVRDGDSYLVVASKGGAPRHPGWYYNLKANPRVRVQI 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 521983411   89 GRRRRPATAEIVSrdDDRHAALLAKCDAVNRGrYSAYQHRTERPIPIVVLT 139
Cdd:pfam04075  82 GGRWLDGTARLAP--DDERARLWQLPVLNSPG-YAVYQSGTDRPIPVVVLT 129
hi_GC_TIGR00026 TIGR00026
deazaflavin-dependent oxidoreductase, nitroreductase family; This model represents a family of ...
 24-139 9.10e-30

deazaflavin-dependent oxidoreductase, nitroreductase family; This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 211538  Cd Length: 113  Bit Score: 104.03  E-value: 9.10e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521983411   24 GHRLLGMPTLLLRTIGRRSGQARTSALVYAREDDAYLVVASDGGARTSPAWLHNLRAEPECEIQIGRRRRPATAEIVSRD 103
Cdd:TIGR00026   1 GGIARGLPVLLLTTTGRKTGKPRTTPVYYVRHDPGVLVVASNGGAPRHPDWYKNLKANPRVRVRVGGKVFVATARLVSGD 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 521983411  104 DDRHaaLLAKCDAVNrGRYSAYQHRTERPIPIVVLT 139
Cdd:TIGR00026  81 ERAQ--LWAGVVRLY-PRYQRYQSRTDRPIPVVVLT 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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