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pyrimidine/purine nucleoside phosphorylase [Hahella ganghwensis]
pyrimidine/purine nucleoside phosphorylase( domain architecture ID 10006942)
pyrimidine/purine nucleoside phosphorylase catalyzes the phosphorolysis of diverse nucleosides, such as uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine, yielding D-ribose 1-phosphate and the respective free bases; also catalyzes the reverse reactions
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
PpnP | COG3123 | Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family [Nucleotide ... |
1-91 | 3.56e-55 | |||
Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family [Nucleotide transport and metabolism]; : Pssm-ID: 442357 Cd Length: 99 Bit Score: 165.72 E-value: 3.56e-55
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Name | Accession | Description | Interval | E-value | |||
PpnP | COG3123 | Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family [Nucleotide ... |
1-91 | 3.56e-55 | |||
Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family [Nucleotide transport and metabolism]; Pssm-ID: 442357 Cd Length: 99 Bit Score: 165.72 E-value: 3.56e-55
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Ppnp | pfam06865 | Pyrimidine/purine nucleoside phosphorylase; This family consist of YaiE and related proteins. ... |
2-92 | 3.68e-54 | |||
Pyrimidine/purine nucleoside phosphorylase; This family consist of YaiE and related proteins. YaiE from E. coli catalyzes phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and free bases. Pssm-ID: 462023 Cd Length: 92 Bit Score: 163.04 E-value: 3.68e-54
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cupin_PpnP-like | cd20296 | pyrimidine/purine nucleoside phosphorylase and related proteins, cupin domain; This family ... |
4-92 | 1.58e-44 | |||
pyrimidine/purine nucleoside phosphorylase and related proteins, cupin domain; This family includes cupin domain proteins that are homologous to pyrimidine/purine nucleoside phosphorylase PpnP. Purine and pyrimidine nucleoside phosphorylases are key enzymes of the nucleoside salvage pathway; they catalyze the reversible phosphorolytic cleavage of the glycosidic bond of purine and pyrimidine nucleosides. Nucleoside phosphorylases are of medical interest since phosphorylases can be used in activating prodrugs; high-molecular mass purine nucleoside phosphorylases may be used in gene therapy of some solid tumors and their inhibitors could be selective immunosuppressive, anticancer, and antiparasitic agents. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization. Pssm-ID: 380430 Cd Length: 90 Bit Score: 138.48 E-value: 1.58e-44
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PRK10579 | PRK10579 | pyrimidine/purine nucleoside phosphorylase; |
1-92 | 8.19e-37 | |||
pyrimidine/purine nucleoside phosphorylase; Pssm-ID: 182565 Cd Length: 94 Bit Score: 119.13 E-value: 8.19e-37
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Name | Accession | Description | Interval | E-value | |||
PpnP | COG3123 | Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family [Nucleotide ... |
1-91 | 3.56e-55 | |||
Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family [Nucleotide transport and metabolism]; Pssm-ID: 442357 Cd Length: 99 Bit Score: 165.72 E-value: 3.56e-55
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Ppnp | pfam06865 | Pyrimidine/purine nucleoside phosphorylase; This family consist of YaiE and related proteins. ... |
2-92 | 3.68e-54 | |||
Pyrimidine/purine nucleoside phosphorylase; This family consist of YaiE and related proteins. YaiE from E. coli catalyzes phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and free bases. Pssm-ID: 462023 Cd Length: 92 Bit Score: 163.04 E-value: 3.68e-54
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cupin_PpnP-like | cd20296 | pyrimidine/purine nucleoside phosphorylase and related proteins, cupin domain; This family ... |
4-92 | 1.58e-44 | |||
pyrimidine/purine nucleoside phosphorylase and related proteins, cupin domain; This family includes cupin domain proteins that are homologous to pyrimidine/purine nucleoside phosphorylase PpnP. Purine and pyrimidine nucleoside phosphorylases are key enzymes of the nucleoside salvage pathway; they catalyze the reversible phosphorolytic cleavage of the glycosidic bond of purine and pyrimidine nucleosides. Nucleoside phosphorylases are of medical interest since phosphorylases can be used in activating prodrugs; high-molecular mass purine nucleoside phosphorylases may be used in gene therapy of some solid tumors and their inhibitors could be selective immunosuppressive, anticancer, and antiparasitic agents. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization. Pssm-ID: 380430 Cd Length: 90 Bit Score: 138.48 E-value: 1.58e-44
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PRK10579 | PRK10579 | pyrimidine/purine nucleoside phosphorylase; |
1-92 | 8.19e-37 | |||
pyrimidine/purine nucleoside phosphorylase; Pssm-ID: 182565 Cd Length: 94 Bit Score: 119.13 E-value: 8.19e-37
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cupin_Mj0764-like | cd20290 | uncharacterized Methanocaldococcus jannaschii Mj0764 and related proteins, cupin domain; This ... |
28-81 | 5.41e-04 | |||
uncharacterized Methanocaldococcus jannaschii Mj0764 and related proteins, cupin domain; This family includes archaeal and bacterial proteins homologous to MJ0764, a Methanocaldococcus jannaschii protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization. Pssm-ID: 380424 [Multi-domain] Cd Length: 100 Bit Score: 35.64 E-value: 5.41e-04
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cupin_TcmJ-like | cd06991 | TcmJ monooxygenase and related proteins, cupin domain; This family includes TcmJ, a subunit of ... |
23-73 | 2.08e-03 | |||
TcmJ monooxygenase and related proteins, cupin domain; This family includes TcmJ, a subunit of the tetracenomycin (TCM) polyketide synthase (PKS) type II complex in Streptomyces glaucescens. TcmJ is a quinone-forming monooxygenase involved in the modification of aromatic polyketides synthesized by polyketide synthases of types II and III. Orthologs of TcmJ include the Streptomyces BenD (benastatin biosynthetic pathway), the Streptomyces olivaceus ElmJ (polyketide antibiotic elloramycin biosynthetic pathway), the Actinomadura hibisca PdmL (pradimicin biosynthetic pathway), the Streptomyces cyaneus CurC (curamycin biosynthetic pathway), the Streptomyces rishiriensis Lct30 (lactonamycin biosynthetic pathway), and the Streptomyces WhiE II (spore pigment polyketide biosynthetic pathway). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization. Pssm-ID: 380396 [Multi-domain] Cd Length: 105 Bit Score: 34.19 E-value: 2.08e-03
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COG3450 | COG3450 | Predicted enzyme of the cupin superfamily [General function prediction only]; |
15-77 | 4.39e-03 | |||
Predicted enzyme of the cupin superfamily [General function prediction only]; Pssm-ID: 442673 Cd Length: 108 Bit Score: 33.42 E-value: 4.39e-03
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Blast search parameters | ||||
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