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Conserved domains on  [gi|519083524|ref|WP_020239399|]
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MULTISPECIES: signal peptidase II [Escherichia]

Protein Classification

signal peptidase II( domain architecture ID 10001765)

signal peptidase II specifically catalyzes the removal of signal peptides from membrane prolipoproteins; it belongs to the peptidase family A8

EC:  3.4.23.36
Gene Ontology:  GO:0004190|GO:0006508
MEROPS:  A8
PubMed:  31214988

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-163 5.80e-60

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 182.61  E-value: 5.80e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPS-LNLHYARNYGAAFSFLADSGgwqrWFFAGIAIGISVILAVMMY 88
Cdd:COG0597    1 LLFLLLALLVLLLDQLTKLWVVANLALGESIPVIGGfFNLTYVENTGAAFGLLAGAG----WLLIILALVVLVGLLYYLR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 519083524  89 RSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFLPSKAKK 163
Cdd:COG0597   77 RLKKRSKLLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGGWHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-163 5.80e-60

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 182.61  E-value: 5.80e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPS-LNLHYARNYGAAFSFLADSGgwqrWFFAGIAIGISVILAVMMY 88
Cdd:COG0597    1 LLFLLLALLVLLLDQLTKLWVVANLALGESIPVIGGfFNLTYVENTGAAFGLLAGAG----WLLIILALVVLVGLLYYLR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 519083524  89 RSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFLPSKAKK 163
Cdd:COG0597   77 RLKKRSKLLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGGWHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 1-164 1.36e-59

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 182.56  E-value: 1.36e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524    1 MSQSIcSTGLRWLWLVVVVLI-IDLGSKYLILQNFALGDT--VPLFPSLNLHYARNYGAAFSFLADSGGwQRWFFAGIAI 77
Cdd:TIGR00077   1 MSQSL-SKGLLLYWLVAILFIgFDQLSKYLVLQNFDLGETyfVAFSGVFNITYVRNTGAAFSLLADQGG-QVYFLKGLAI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524   78 GISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFL 157
Cdd:TIGR00077  79 AISLGLFVFLLRYKELFKITNIAFGLIFGGALGNFIDRLVRGGVVDFFDFYFGNYHFPIFNFADSSICIGVILLLLYFFF 158


                  ....*..
gi 519083524  158 PSKAKKQ 164
Cdd:TIGR00077 159 PKRKKKK 165
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
15-157 3.81e-46

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 147.23  E-value: 3.81e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524   15 LVVVVLIIDLGSKYLILQNFALGDTVPLFP-SLNLHYARNYGAAFSFLADsggwQRWFFAGIAIGISVILAVMMYRSKAT 93
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPgFFNLTYVENTGAAFGLLAG----QRWLLIILTLVAIILLIYLLLKLKKK 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 519083524   94 QKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFL 157
Cdd:pfam01252  77 SRLLRIALALILGGALGNLIDRLFYGYVVDFIDFHIGFINFPVFNVADIAITVGVILLIIDLLF 140
PRK14785 PRK14785
lipoprotein signal peptidase; Provisional
 10-163 4.03e-40

lipoprotein signal peptidase; Provisional


Pssm-ID: 184820  Cd Length: 171  Bit Score: 133.02  E-value: 4.03e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLF-PSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMY 88
Cdd:PRK14785  15 LNWYLLSLVVLILDQWTKWLAETKLTFLEPVPVIePFLNWTLAYNYGAAFSFLADAGGWQKWFFAGLALIMSLFLIVYLK 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 519083524  89 RSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDF-YVGGWHFATFNLADTAICVGAAMIVLEG-FLPSKAKK 163
Cdd:PRK14785  95 KAPRQAKLLSLGLALVLGGAIGNLIDRLLHGHVIDFIHVhYADVWHYPIFNIADIGICVGVALIVIDMlFLEKKRNA 171
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-163 5.80e-60

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 182.61  E-value: 5.80e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPS-LNLHYARNYGAAFSFLADSGgwqrWFFAGIAIGISVILAVMMY 88
Cdd:COG0597    1 LLFLLLALLVLLLDQLTKLWVVANLALGESIPVIGGfFNLTYVENTGAAFGLLAGAG----WLLIILALVVLVGLLYYLR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 519083524  89 RSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFLPSKAKK 163
Cdd:COG0597   77 RLKKRSKLLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGGWHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 1-164 1.36e-59

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 182.56  E-value: 1.36e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524    1 MSQSIcSTGLRWLWLVVVVLI-IDLGSKYLILQNFALGDT--VPLFPSLNLHYARNYGAAFSFLADSGGwQRWFFAGIAI 77
Cdd:TIGR00077   1 MSQSL-SKGLLLYWLVAILFIgFDQLSKYLVLQNFDLGETyfVAFSGVFNITYVRNTGAAFSLLADQGG-QVYFLKGLAI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524   78 GISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFL 157
Cdd:TIGR00077  79 AISLGLFVFLLRYKELFKITNIAFGLIFGGALGNFIDRLVRGGVVDFFDFYFGNYHFPIFNFADSSICIGVILLLLYFFF 158


                  ....*..
gi 519083524  158 PSKAKKQ 164
Cdd:TIGR00077 159 PKRKKKK 165
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
15-157 3.81e-46

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 147.23  E-value: 3.81e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524   15 LVVVVLIIDLGSKYLILQNFALGDTVPLFP-SLNLHYARNYGAAFSFLADsggwQRWFFAGIAIGISVILAVMMYRSKAT 93
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPgFFNLTYVENTGAAFGLLAG----QRWLLIILTLVAIILLIYLLLKLKKK 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 519083524   94 QKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFL 157
Cdd:pfam01252  77 SRLLRIALALILGGALGNLIDRLFYGYVVDFIDFHIGFINFPVFNVADIAITVGVILLIIDLLF 140
PRK14785 PRK14785
lipoprotein signal peptidase; Provisional
 10-163 4.03e-40

lipoprotein signal peptidase; Provisional


Pssm-ID: 184820  Cd Length: 171  Bit Score: 133.02  E-value: 4.03e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLF-PSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMY 88
Cdd:PRK14785  15 LNWYLLSLVVLILDQWTKWLAETKLTFLEPVPVIePFLNWTLAYNYGAAFSFLADAGGWQKWFFAGLALIMSLFLIVYLK 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 519083524  89 RSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDF-YVGGWHFATFNLADTAICVGAAMIVLEG-FLPSKAKK 163
Cdd:PRK14785  95 KAPRQAKLLSLGLALVLGGAIGNLIDRLLHGHVIDFIHVhYADVWHYPIFNIADIGICVGVALIVIDMlFLEKKRNA 171
PRK14776 PRK14776
lipoprotein signal peptidase; Provisional
 23-162 1.02e-35

lipoprotein signal peptidase; Provisional


Pssm-ID: 173237  Cd Length: 170  Bit Score: 121.97  E-value: 1.02e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  23 DLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKatQKLNNIAYA 102
Cdd:PRK14776  24 DQAVKWLVQQSMAYGEYVSVTPFFNWVHLWNTGAAFSLFANGGGWQRYFFIGIAVVVSIFLIKLILENR--HKGEAIAYS 101

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524 103 LIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFLPSKAK 162
Cdd:PRK14776 102 LILGGAMGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLFVSSSLLGKKAN 161
PRK14791 PRK14791
lipoprotein signal peptidase; Provisional
 12-152 8.12e-30

lipoprotein signal peptidase; Provisional


Pssm-ID: 237817 [Multi-domain]  Cd Length: 146  Bit Score: 106.18  E-value: 8.12e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  12 WLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSL-NLHYARNYGAAFSFLADsggwQRWFFAGIAIGISVILAVMMYRS 90
Cdd:PRK14791   2 EIIIIILGIFLDQLTKIWALKNLASGGDIPVIKNFfSLTYVENRGAAFGILQN----KTLFLILITIIVILGLIYYIIKY 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 519083524  91 KATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIV 152
Cdd:PRK14791  78 KPTSKLYKISLSLIISGAIGNLIDRIRYGYVVDFIDFHFKDYYFPVFNVADILVVVGTILLA 139
PRK14770 PRK14770
lipoprotein signal peptidase; Provisional
 15-157 4.63e-25

lipoprotein signal peptidase; Provisional


Pssm-ID: 173231  Cd Length: 167  Bit Score: 94.50  E-value: 4.63e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  15 LVVVVLIIDLGSKYLILQNFALGD--TVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSka 92
Cdd:PRK14770  16 LLVAVLLLDQASKYWILYGLDLPDrgSVPVLPFLNFTMVWNHAVTFGMLGGLGGIGRVVFSAVSLAAVLLLGVWLTRT-- 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 519083524  93 TQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFL 157
Cdd:PRK14770  94 PRPLVAAALGAIMGGAIGNVIDRMRYGAVVDFLHAHAFGWSWYVFNLADAAIDCGVAVLLIDSLL 158
PRK14779 PRK14779
lipoprotein signal peptidase; Provisional
 10-163 2.38e-22

lipoprotein signal peptidase; Provisional


Pssm-ID: 184818  Cd Length: 159  Bit Score: 87.07  E-value: 2.38e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLIlQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAvMMYR 89
Cdd:PRK14779   6 LAYLGTFFLVLVLDLITKYLA-EKYLFDKDISVIPFLDLVLVYNKGVAFGLLSEAPDFIRLPILLLTPIIALIIT-FLYA 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 519083524  90 SKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVGAAMIVLEGFLPSKAKK 163
Cdd:PRK14779  84 LKSNDKLSNLSMGLIGGGALGNLYDRFFLGQVRDFIDIYIGDFHWPAFNIADASISIGIALFILYEHFFKKRKK 157
PRK14773 PRK14773
lipoprotein signal peptidase; Provisional
 41-164 1.86e-20

lipoprotein signal peptidase; Provisional


Pssm-ID: 173234  Cd Length: 192  Bit Score: 83.36  E-value: 1.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  41 PLFPSLNLHYARNYGAAFSFLAD-SGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHG 119
Cdd:PRK14773  65 VWRPVWRMNYVENPGAAWGLFRGhSEEFRNAFFTLVSLAAVAFILHYYRKLRQEQRYLQVALALVLGGAVGNFVDRLARG 144

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 519083524 120 FVVDMIDFY---VGGWHFATFNLADTAICVGAAMIVLEGFLPSKAKKQ 164
Cdd:PRK14773 145 YVIDFIEWYwwnRPDIRWPTFNVADSLIVVGVAMLVLHPGSRKEAPRA 192
PRK14784 PRK14784
lipoprotein signal peptidase; Provisional
 20-153 5.42e-14

lipoprotein signal peptidase; Provisional


Pssm-ID: 184819 [Multi-domain]  Cd Length: 160  Bit Score: 65.65  E-value: 5.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  20 LIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSggwQRWFFAGIAIGISVILAVMMYRSKA---TQKL 96
Cdd:PRK14784  15 ILADQLSKFIITANLTTGTSIPESGFFQIVHVHNTGAAFSIFRGH---IEWLIAASVLGVILAMTAFFIRKKLpflDTRP 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 519083524  97 NNIAYALIIGGALGNLFDRLWHGFVVDMIDfyVGGWhfATFNLADTAICVGAAMIVL 153
Cdd:PRK14784  92 GLIALGVILAGTVGNLIDRVRLGYVTDFIR--VGDF--PTFNIADSCLTVGVIGLLL 144
PRK14789 PRK14789
lipoprotein signal peptidase; Provisional
 11-153 1.56e-13

lipoprotein signal peptidase; Provisional


Pssm-ID: 173250  Cd Length: 191  Bit Score: 65.06  E-value: 1.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  11 RWLWLVVV---VLIIDLGSKYLiLQNFALGDTVP---LFPSLNLHYARNYGAAFSFLADSGGwqrwfFAGIAIGISVILA 84
Cdd:PRK14789   4 RWMLLVLVaipVFVIDQLSKVW-LSDVLLRYNRPiplLFDWVQLAYHENTGVAFGLFPDQGG-----VLSVGAGLVLLLL 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 519083524  85 VMMYRS--KATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFyvgGWhFATFNLADTAICVGAAMIVL 153
Cdd:PRK14789  78 ALTYQYilPADSRWITVAVGMIFGGGLSNLVDRIRQGYVVDFIQF---GW-WPVFNLADSAITIGVAALAF 144
PRK14787 PRK14787
lipoprotein signal peptidase; Provisional
 15-153 1.62e-13

lipoprotein signal peptidase; Provisional


Pssm-ID: 173248  Cd Length: 159  Bit Score: 64.25  E-value: 1.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  15 LVVVVLIIDLGSKYL-ILQNFALGDTVPLFPS-LNLHYARNYGAAFSFLADSggwqRWFFAGIAIGISVILAVMMYRSKA 92
Cdd:PRK14787   7 LALAVIVLDQFTKKLaITFLRDGPQSITIIPDwFKLTYAENRGIAFGLEFAP----PEVLLLLTGAISAGVLWYVLRSKN 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 519083524  93 TQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDF-----YVGGWHFA---TFNLADTAICVGAAMIVL 153
Cdd:PRK14787  83 RTPLFLLAFGLILGGGIGNLIDRITSGRVVDFIYFdlyqgYIFGIWVSlwpIFNIADSAITIGACMLLL 151
PRK14767 PRK14767
lipoprotein signal peptidase; Provisional
 15-153 2.10e-13

lipoprotein signal peptidase; Provisional


Pssm-ID: 237811  Cd Length: 174  Bit Score: 64.34  E-value: 2.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  15 LVVVVLIIDLGSKYLILQNFALGDTVPLFP-SLNLHYARNYGAAFSFLADsggwQRWFFAGIAIGISVILAVMMYRSKAT 93
Cdd:PRK14767  16 LFVILVILDQITKYLAVSHLADKPSFVIIPgVFELIYLENSGAAFGMLSG----KAVFFLVITVAVVIIMAFVFFKLPAT 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 519083524  94 QKLN--NIAYALIIGGALGNLFDRLWHGFVVDMIDFYVggWHFATFNLADTAICVGAAMIVL 153
Cdd:PRK14767  92 KKYNplHIILVFIVAGAAGNLIDRILNGYVVDFIYFKL--INFPIFNVADIYVTVSTFLFII 151
PRK14788 PRK14788
lipoprotein signal peptidase; Provisional
 15-153 1.06e-11

lipoprotein signal peptidase; Provisional


Pssm-ID: 237816  Cd Length: 200  Bit Score: 59.98  E-value: 1.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  15 LVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLAdSGGWQRWF---FAGIAI-GISVILAVMMYRS 90
Cdd:PRK14788   7 IILLVLLIDQISKIYVKTHFVLGQSVLVFDWFKIHFVENPGMAFGMEL-GGEYGKLFltlFRIVAVgGIGYYLWKLVKKN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  91 KATQKLnnIAYALIIGGALGNLFDR---------------------------LWHGFVVDMIDF------------YVGG 131
Cdd:PRK14788  86 SSKGLI--ICISLILAGAIGNIIDSvfygvifdngsygqiatffpegggystWFHGKVVDMFYFpiidgylpewvpFWGG 163

                        170       180
                 ....*....|....*....|....*.
gi 519083524 132 WHFAT----FNLADTAICVGAAMIVL 153
Cdd:PRK14788 164 EHFVFfkpvFNIADSAISIGVILLLL 189
PRK14772 PRK14772
lipoprotein signal peptidase; Provisional
 17-153 1.50e-11

lipoprotein signal peptidase; Provisional


Pssm-ID: 237812 [Multi-domain]  Cd Length: 190  Bit Score: 59.50  E-value: 1.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  17 VVVLIIDLGSKYLILQNFALGDTVPLFPS-LNLHYARNYGAAFSFladsGGWQRWFFAGIAIGISVilAVMMYRSKATQK 95
Cdd:PRK14772  33 VFAYVFDQLTKLWVTSTMVEGERIPVLPPlLHWYYIRNSGAAFSI----GENVTWVFSIIMAAVAV--AILVQLRKLGSA 106

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 519083524  96 LNNIAYALIIGGALGNLFDRLWH------GFVVDMIDFYvggwHFATFNLADTAICVGAAMIVL 153
Cdd:PRK14772 107 WWALALGLLLGGALGNLTDRLFRepsfgmGHVVDFIQLP----NFAIFNIADSAVVSGVVIICL 166
PRK14775 PRK14775
lipoprotein signal peptidase; Provisional
 16-147 1.83e-11

lipoprotein signal peptidase; Provisional


Pssm-ID: 237813  Cd Length: 170  Bit Score: 59.13  E-value: 1.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  16 VVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLA--DSGGWqrwFFAGIAIGISVILAVMMYRSKAT 93
Cdd:PRK14775  11 IVLVFALDQVSKAYAIDWYSQSGATEVFKFCSLVEVWNRGISFGMFGalESSNL---IFTYVSLGVILMLFVLFVQSKCN 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 519083524  94 QKlnNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFATFNLADTAICVG 147
Cdd:PRK14775  88 KS--TICMGVVIGGALGNLADRLRFGAVYDFISLHAGEFHWPAFNFADVCVTCG 139
PRK14781 PRK14781
lipoprotein signal peptidase; Provisional
 44-160 1.86e-11

lipoprotein signal peptidase; Provisional


Pssm-ID: 237815  Cd Length: 153  Bit Score: 58.67  E-value: 1.86e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  44 PSLNLHYARNYGAAFSFLADSGGWqrWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVD 123
Cdd:PRK14781  37 GLINIRLLYNTGVAFSLGAGLPTW--FVIAGTGLIIAALLWYLTSSAPKMSRLSRAGAALLLGGAVGNFIDRLDGRGVVD 114

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 519083524 124 MIDfyvGGWhFATFNLADTAICVGAAMIVLEGFLPSK 160
Cdd:PRK14781 115 YLH---SGW-FPTFNLADVFVTTGVALLVLGMLRPPK 147
PRK14790 PRK14790
lipoprotein signal peptidase; Provisional
 11-153 4.27e-11

lipoprotein signal peptidase; Provisional


Pssm-ID: 173251  Cd Length: 169  Bit Score: 57.95  E-value: 4.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  11 RWLWLVVVVLII---DLGSKYLILQNFALGDTVPLFP----SLNLHYARNYGAAFSFLAdsgGWQRWFFAGIAIGISVIL 83
Cdd:PRK14790   8 RWITPALVAATIlalDQASKRWILATLGPVPMTKFIPligeDIRLAYSHNTGIAFSLFD---GKSDILTVVALVISLGAI 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  84 AVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFyvgGWhFATFNLADTAICVGAAMIVL 153
Cdd:PRK14790  85 YLYRTQLPNRRLLIQVAMGLILGGALGNVIDRIRLGYVVDFIQV---GW-FPIFNLADSAITVGAALLML 150
PRK14778 PRK14778
lipoprotein signal peptidase; Provisional
 13-156 1.67e-10

lipoprotein signal peptidase; Provisional


Pssm-ID: 173239  Cd Length: 186  Bit Score: 56.75  E-value: 1.67e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  13 LWLVVVVLIIDLGSKYLILQNFALGDTVPLFpsLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVmmyrsKA 92
Cdd:PRK14778   2 MFVIVLTIVLDQLTKRIASEIHGTFFIVPGF--LRFVKATNRGVALGLFSNLSEQVLWTVLFVVVFLSLLPYI-----FR 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 519083524  93 TQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYvggWHFATFNLADTAICVGAAMIVLEGF 156
Cdd:PRK14778  75 FSRLERMAMGFILGGALGNLLDRIRFGYVLDFLNLT---FLPTIFNLADVFIIVGGALMILGVF 135
PRK14774 PRK14774
lipoprotein signal peptidase; Provisional
 18-153 1.39e-09

lipoprotein signal peptidase; Provisional


Pssm-ID: 173235  Cd Length: 185  Bit Score: 54.25  E-value: 1.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  18 VVLIIDLGSKYLILQNFAL---GDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATq 94
Cdd:PRK14774  10 GVFVLDQLTKWLVVWGLDLanrGAIDLVAPWLTFRMAWNRGINFGIGSSDQEIVRWGLVIVSLAISAWVWRWVWRSTPT- 88

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  95 KLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGGWHFA-TFNLADTAICVGAAMIVL 153
Cdd:PRK14774  89 RLARISGGLLIGGALGNVVDRVLYGAVADFLNMSCCGIENPyAFNVADIAIFAGAFGLVL 148
PRK14768 PRK14768
lipoprotein signal peptidase; Provisional
 13-153 4.24e-09

lipoprotein signal peptidase; Provisional


Pssm-ID: 173229  Cd Length: 148  Bit Score: 52.21  E-value: 4.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  13 LWLVVVVLIIDLG--SKYLILQNFALGDTVPLFPSL-NLHYARNYGAAFSFLADSggwqRWFFAGIAIgISVILAVMMYR 89
Cdd:PRK14768   2 LYILIIILLIGLDqlSKIWVLNNLVDVSTIPIINNVfHLTYVENRGAAFGLLQNN----QWIFIIVAL-LATVFGLYYLN 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 519083524  90 SKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVgGWHFaTFNLADTAICVGAAMIVL 153
Cdd:PRK14768  77 TRKVHIFGRLGIILIISGALGNLIDRVRLGFVVDYFDFRV-IWEY-VFNVADVFVVVGTVFLCI 138
PRK14786 PRK14786
lipoprotein signal peptidase; Provisional
 10-164 4.99e-09

lipoprotein signal peptidase; Provisional


Pssm-ID: 173247  Cd Length: 154  Bit Score: 52.29  E-value: 4.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSL-NLHYARNYGAAFSFLADsggwQRWFFAGIAIGISVILAVMMY 88
Cdd:PRK14786   1 MFYIFIITILTGIDQWTKYLIETQLKPIGAIPIVKDIfHLTYARNTGAAFSILRD----KQAFLILVTTIVVGALIYYLI 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 519083524  89 RSKATQK-LNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVggWHFATFNLADTAICVGAAMIVLEGFLPSKAKKQ 164
Cdd:PRK14786  77 KILKTGEvAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTL--INYPIFNLADVFVVSGVVMLSYMLLFKGDMPKI 151
PRK14769 PRK14769
lipoprotein signal peptidase; Provisional
 17-164 6.31e-09

lipoprotein signal peptidase; Provisional


Pssm-ID: 173230  Cd Length: 156  Bit Score: 51.85  E-value: 6.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  17 VVVLIIDLGSKYLILQNFAlGDTVPLfPSLNLHYARNYGAAFSfLADSggWQRWFFAGIAIGISVILAVMMYRSKATQKL 96
Cdd:PRK14769  13 VIIAGIDLGAKAWSERQLA-GSSVDL-GLLHLRLAFNSGVAFS-MGDT--LPVGVIVAVTAVIVVALAVYAWRRAPTAGW 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 519083524  97 -NNIAYALIIGGALGNLFDRLWHGFVVDMIDfyvGGWhFATFNLADTAICVGAAMIVLEGFLPSKAKKQ 164
Cdd:PRK14769  88 vERIAGGAVIGGALANVVDRARDGLVTDYLH---TGW-WPTFNLADTFLVTGFAVIALLHARPERTADT 152
PRK14771 PRK14771
lipoprotein signal peptidase; Provisional
 15-153 2.26e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 184816  Cd Length: 165  Bit Score: 47.89  E-value: 2.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  15 LVVVVLIIDLGSKYLILQNFALGDTVPLFPS-LNLHYARNYGAAFSFladsGGWQRWFFAGIAIGISVILAVMMYRSKAT 93
Cdd:PRK14771  18 IAIAALIVDQLTKAWAQAALSDGQTIRVIPGlLSLTLVRNPGASLGM----GSGATWVISLLAIVACVALVVAAVRTISM 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 519083524  94 QKlnNIAYALIIGGALGNLFDRLWH------GFVVDMIDFyvgGWHFAtfNLADTAICVGAAMIVL 153
Cdd:PRK14771  94 KW--TVALALAFAGALGNLIDRVMYaqgflnGKVVDFLNY---GWSVG--NVADIFLMIAGIALVI 152
PRK14777 PRK14777
lipoprotein signal peptidase; Provisional
 11-162 3.99e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 237814 [Multi-domain]  Cd Length: 184  Bit Score: 47.54  E-value: 3.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  11 RWLWLVVVVLII--DLGSKYLILQNFALG-DTVPLFPS-LNLHYARNYGAAFSFLadSGGWQRWFFAGIAIGISVILAVM 86
Cdd:PRK14777  26 AWAPLVLATLLIvlDQALKAWALANLQLGaPAIPVLPGvLDWVLTFNTGAAWSLF--SGSALPLALMRLLVGLGLLVYLL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  87 MyrsKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDM--------IDFYVGGWHFATFNLADTAICVGAAMIVLEGFLP 158
Cdd:PRK14777 104 R---RPQPRFLTVVLSLIAAGAIGNAIDGLRFGRVTDMlhspalsaVTRALGQGDFPIFNLADMCVVGGTLLLLFASFQQ 180


                 ....
gi 519083524 159 SKAK 162
Cdd:PRK14777 181 DRKR 184
PRK14783 PRK14783
lipoprotein signal peptidase; Provisional
 12-153 7.05e-03

lipoprotein signal peptidase; Provisional


Pssm-ID: 173244  Cd Length: 182  Bit Score: 35.61  E-value: 7.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  12 WLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPS-LNLHYARNYGAAFSFLADSGgwqrwFFAGIAIGISVILaVMMYRS 90
Cdd:PRK14783  16 YLGVIFLGIFLDLVTKFLVILYFYPHRYLEVLGSfFRMTLTFNTGFVFGAFQDNA-----IPSLIATGFAIVF-LIGYRW 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519083524  91 KATQKLNNIAYALIIGGALGNLFDRLW---------HGF---------VVDMIDF----YVGGWHFATFNLADTAICVGA 148
Cdd:PRK14783  90 KNSDLGNPWGWNLVMAGAFGNFLDKFFvkipgtgfrFGFqpnkgeyigVVDFLDFdwpdFLLFSRWPAFNVADSCVTIGL 169


                 ....*
gi 519083524 149 AMIVL 153
Cdd:PRK14783 170 TILIF 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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