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Conserved domains on  [gi|518384895|ref|WP_019555102|]
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tagatose bisphosphate family class II aldolase [Propionispira raffinosivorans]

Protein Classification

tagatose-bisphosphate aldolase subunit GatY( domain architecture ID 10793695)

tagatose-bisphosphate aldolase subunit GatY is the catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
2-285 0e+00

tagatose-bisphosphate aldolase subunit GatY;


:

Pssm-ID: 183710  Cd Length: 284  Bit Score: 513.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   2 HTILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALH 81
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  82 LDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAA 161
Cdd:PRK12737  81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAMYTNPDAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 162 KLFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFS 241
Cdd:PRK12737 161 AEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 518384895 242 GAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANRY 285
Cdd:PRK12737 241 DAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
 
Name Accession Description Interval E-value
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
2-285 0e+00

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 513.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   2 HTILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALH 81
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  82 LDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAA 161
Cdd:PRK12737  81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAMYTNPDAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 162 KLFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFS 241
Cdd:PRK12737 161 AEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 518384895 242 GAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANRY 285
Cdd:PRK12737 241 DAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
tag_bisphos_ald TIGR01858
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ...
 4-284 3.20e-162

class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.


Pssm-ID: 130917  Cd Length: 282  Bit Score: 452.00  E-value: 3.20e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:TIGR01858   1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKHAGTEYIVALCSAASTTYNMPLALHLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAKL 163
Cdd:TIGR01858  81 HHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDDLSVDEEDALYTDPQEAKE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  164 FVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGA 243
Cdd:TIGR01858 161 FVEATGVDSLAVAIGTAHGLYKKTPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIAFSGA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 518384895  244 IKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:TIGR01858 241 VKAYFAENPQANDPRYYMRPGKDAMKKVVRNKINVCGSAGR 281
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 6-284 1.51e-150

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 422.19  E-value: 1.51e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   6 STKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLDHH 85
Cdd:COG0191    4 SLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYLAAMVRAAAEEASVPVALHLDHG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  86 ENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAKLFV 165
Cdd:COG0191   84 ASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDDAEALYTDPEEAAEFV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 166 EATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIK 245
Cdd:COG0191  164 EETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVR 243

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 518384895 246 EFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:COG0191  244 EYLAENPDKYDPRKYLKPAREAMKEVVKEKIRLFGSAGK 282
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 7-283 2.76e-139

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 393.43  E-value: 2.76e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   7 TKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLDHHE 86
Cdd:cd00947    1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELLVAMVKAAAERASVPVALHLDHGS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  87 NVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEAdsAYTNPDAAKLFVE 166
Cdd:cd00947   81 SFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDEG--LLTDPEEAEEFVE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 167 ATGIDSLAIAIGTAHGLYKG-TPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIK 245
Cdd:cd00947  159 ETGVDALAVAIGTSHGAYKGgEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALR 238

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 518384895 246 EFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSAN 283
Cdd:cd00947  239 EYLAENPKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
6-284 4.19e-139

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 392.93  E-value: 4.19e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    6 STKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTY--ANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:pfam01116   2 NLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKyaGGAEALAALVRAAAEAAGVPVALHLD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEAdsAYTNPDAAKL 163
Cdd:pfam01116  82 HGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEK--LYTDPEEAAE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  164 FVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGA 243
Cdd:pfam01116 160 FVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAA 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 518384895  244 IKEFflanPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:pfam01116 240 VREY----PPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
 
Name Accession Description Interval E-value
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
2-285 0e+00

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 513.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   2 HTILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALH 81
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  82 LDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAA 161
Cdd:PRK12737  81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAMYTNPDAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 162 KLFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFS 241
Cdd:PRK12737 161 AEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 518384895 242 GAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANRY 285
Cdd:PRK12737 241 DAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 4-284 4.89e-170

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 471.53  E-value: 4.89e-170
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:PRK09195   3 LVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYAGTEYLLAIVSAAAKQYHHPLALHLD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAKL 163
Cdd:PRK09195  83 HHEKFDDIAQKVRSGVRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDLQVDEADALYTDPAQARE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 164 FVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGA 243
Cdd:PRK09195 163 FVEATGIDSLAVAIGTAHGMYKGEPKLDFDRLENIRQWVNIPLVLHGASGLPTKDIQQTIKLGICKVNVATELKIAFSQA 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 518384895 244 IKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK09195 243 LKNYLTEHPEANDPRHYLQPAKSAMKDVVSKVIADCGCEGK 283
tag_bisphos_ald TIGR01858
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ...
 4-284 3.20e-162

class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.


Pssm-ID: 130917  Cd Length: 282  Bit Score: 452.00  E-value: 3.20e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:TIGR01858   1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKHAGTEYIVALCSAASTTYNMPLALHLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAKL 163
Cdd:TIGR01858  81 HHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDDLSVDEEDALYTDPQEAKE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  164 FVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGA 243
Cdd:TIGR01858 161 FVEATGVDSLAVAIGTAHGLYKKTPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIAFSGA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 518384895  244 IKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:TIGR01858 241 VKAYFAENPQANDPRYYMRPGKDAMKKVVRNKINVCGSAGR 281
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 6-284 1.51e-150

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 422.19  E-value: 1.51e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   6 STKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLDHH 85
Cdd:COG0191    4 SLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYLAAMVRAAAEEASVPVALHLDHG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  86 ENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAKLFV 165
Cdd:COG0191   84 ASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDDAEALYTDPEEAAEFV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 166 EATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIK 245
Cdd:COG0191  164 EETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVR 243

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 518384895 246 EFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:COG0191  244 EYLAENPDKYDPRKYLKPAREAMKEVVKEKIRLFGSAGK 282
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 7-283 2.76e-139

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 393.43  E-value: 2.76e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   7 TKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLDHHE 86
Cdd:cd00947    1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELLVAMVKAAAERASVPVALHLDHGS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  87 NVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEAdsAYTNPDAAKLFVE 166
Cdd:cd00947   81 SFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDEG--LLTDPEEAEEFVE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 167 ATGIDSLAIAIGTAHGLYKG-TPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIK 245
Cdd:cd00947  159 ETGVDALAVAIGTSHGAYKGgEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALR 238

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 518384895 246 EFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSAN 283
Cdd:cd00947  239 EYLAENPKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
6-284 4.19e-139

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 392.93  E-value: 4.19e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    6 STKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTY--ANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:pfam01116   2 NLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKyaGGAEALAALVRAAAEAAGVPVALHLD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEAdsAYTNPDAAKL 163
Cdd:pfam01116  82 HGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEK--LYTDPEEAAE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  164 FVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGA 243
Cdd:pfam01116 160 FVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAA 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 518384895  244 IKEFflanPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:pfam01116 240 VREY----PPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
3-284 2.29e-131

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 373.99  E-value: 2.29e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   3 TILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHL 82
Cdd:PRK12738   2 SIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  83 DHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAK 162
Cdd:PRK12738  82 DHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAK 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 163 LFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSG 242
Cdd:PRK12738 162 RFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAG 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 518384895 243 AIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK12738 242 AVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANR 283
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 3-284 1.49e-121

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 348.92  E-value: 1.49e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    3 TILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTY-ANCEYLIAMAQVAARQ--TDIPIA 79
Cdd:TIGR00167   2 MLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYiAGLGAISAMVKAMSEAypYGVPVA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   80 LHLDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPD 159
Cdd:TIGR00167  82 LHLDHGASEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGVSVADESALYTDPE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  160 AAKLFVEATGIDSLAIAIGTAHGLYKGTPK-LDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKI 238
Cdd:TIGR00167 162 EAKEFVKLTGVDSLAAAIGNVHGVYKGEPKgLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQI 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 518384895  239 PFSGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:TIGR00167 242 AFAAAVRNYYAENKDYYDPRVWLRPGEKAMKEVVLEKIKLFGSANK 287
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
3-284 1.42e-111

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 323.60  E-value: 1.42e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   3 TILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHL 82
Cdd:PRK12857   2 MLVTVAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKYAGIEYISAMVRTAAEKASVPVALHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  83 DHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAK 162
Cdd:PRK12857  82 DHGTDFEQVMKCIRNGFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDITVDEREAAMTDPEEAR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 163 LFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSG 242
Cdd:PRK12857 162 RFVEETGVDALAIAIGTAHGPYKGEPKLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIREAFVA 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 518384895 243 AIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK12857 242 RLREVLEKNPDEIDPRKILGPAREAAKEVIREKIRLFGSAGK 283
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 4-284 3.47e-109

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 317.38  E-value: 3.47e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANC-EYLIAMAQVAARQ-TDIPIALH 81
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGyKMAVAMVKTLIERmSIVPVALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   82 LDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDliVTEADSAYTNPDAA 161
Cdd:TIGR01859  81 LDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDG--VDEKEAELADPDEA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  162 KLFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFS 241
Cdd:TIGR01859 159 EQFVKETGVDYLAAAIGTSHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFT 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 518384895  242 GAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:TIGR01859 239 AAIRKVLTEKKDEYDPRKILGPAREAIKETVKEKMRLFGSAGK 281
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
4-284 3.14e-90

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 270.30  E-value: 3.14e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQV-AARQTDIPIALHL 82
Cdd:PRK05835   2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKImCERYPHIPVALHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  83 DHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAK 162
Cdd:PRK05835  82 DHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 163 LFVEATGIDSLAIAIGTAHGL--YKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPD---------------------ELV 219
Cdd:PRK05835 162 QFVKESQVDYLAPAIGTSHGAfkFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDdvrksyldaggdlkgskgvpfEFL 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 518384895 220 QKAIAMGICKVNVATDLKIPFSGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK05835 242 QESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANK 306
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 7-283 2.99e-85

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 258.97  E-value: 2.99e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   7 TKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTY----------------ANCEYLIAMAQVA 70
Cdd:cd00453    1 VQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFiagkgvksdvpqgaaiLGAISGAHHVHQM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  71 ARQTDIPIALHLDHHENVAT--IKTDIDAG-----------FRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELG 137
Cdd:cd00453   81 AEHYGVPVILHTDHCAKKLLpwIDGLLDAGekhfaatgkplFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 138 KLVGQEDDLIVTEADSA--YTNPDAAKLFVEATG----IDSLAIAIGTAHGLYK-GTPKLDFDRLQQIRSKV-------- 202
Cdd:cd00453  161 CTGGEEDGVDNSHMDASalYTQPEDVDYAYTELSkispRFTIAASFGNVHGVYKkGNVVLTPTILRDSQEYVskkhnlph 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 203 -DIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIKEFFLANPSA------------------NDPRRYMTP 263
Cdd:cd00453  241 nSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYlqgqlgnpkgedqpnkkyYDPRVWLRA 320

                        330       340
                 ....*....|....*....|
gi 518384895 264 GKDAMAKVVEHKIKICGSAN 283
Cdd:cd00453  321 GQTSMIARLEKAFQELNAID 340
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
4-284 3.95e-85

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 257.73  E-value: 3.95e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVA---ARQ--TDIPI 78
Cdd:PRK07084   9 LVNTREMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANATLLRYMAQGAveyAKElgCPIPI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  79 ALHLDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDliVTEADSAYTNP 158
Cdd:PRK07084  89 VLHLDHGDSFELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDE--VSAEHHTYTQP 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 159 DAAKLFVEATGIDSLAIAIGTAHGLYKGTP-----KLDFDRLQQIRSKV-DIPLVLHGASDVPDELVQ------------ 220
Cdd:PRK07084 167 EEVEDFVKKTGVDSLAISIGTSHGAYKFKPgqcppPLRFDILEEIEKRIpGFPIVLHGSSSVPQEYVKtineyggklkda 246

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518384895 221 ---------KAIAMGICKVNVATDLKIPFSGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIK-ICGSANR 284
Cdd:PRK07084 247 igipeeqlrKAAKSAVCKINIDSDGRLAMTAAIRKVFDEKPEEFDPRKYLGPARDELKKLYKHKIInVLGSNGK 320
PRK08185 PRK08185
hypothetical protein; Provisional
 8-284 8.13e-85

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 255.42  E-value: 8.13e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   8 KQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYlIAMAQVAARQTDIPIALHLDHHEN 87
Cdd:PRK08185   2 KELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLGDNF-FAYVRERAKRSPVPFVIHLDHGAT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  88 VATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKlVGQEDDLIVTEADSA-YTNPDAAKLFVE 166
Cdd:PRK08185  81 IEDVMRAIRCGFTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGT-IGNTGTSIEGGVSEIiYTDPEQAEDFVS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 167 ATGIDSLAIAIGTAHGLYK--GTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAI 244
Cdd:PRK08185 160 RTGVDTLAVAIGTAHGIYPkdKKPELQMDLLKEINERVDIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKV 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 518384895 245 KEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK08185 240 REILSDNPSLYEPNQIYPSAIEAAKEVVRHKMDLFNSTGK 279
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 4-284 4.29e-82

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 248.75  E-value: 4.29e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEY-LIAMAQVAARQTDI--PIAL 80
Cdd:PRK08610   3 LVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYtVVKMVEGLMHDLNItiPVAI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  81 HLDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIvteADSA-YTNPD 159
Cdd:PRK08610  83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVV---ADGIiYADPK 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 160 AAKLFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIP 239
Cdd:PRK08610 160 ECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIA 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 518384895 240 FSGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK08610 240 SAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNR 284
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 4-284 6.03e-80

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 243.42  E-value: 6.03e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTY-ANCEYLIAMAQVAARQTDI--PIAL 80
Cdd:PRK07709   3 LVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHmTGFKTVVAMVKALIEEMNItvPVAI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  81 HLDHHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEAdsAYTNPDA 160
Cdd:PRK07709  83 HLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGV--IYADPAE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 161 AKLFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPF 240
Cdd:PRK07709 161 CKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQIEF 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 518384895 241 SGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK07709 241 TKAVREVLNKDQEVYDPRKFIGPGRDAIKATVIGKIREFGSNGK 284
PRK06806 PRK06806
class II aldolase;
4-284 5.22e-79

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 240.81  E-value: 5.22e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:PRK06806   3 LVQMKELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAEVRLNHSPLHLIGPLMVAAAKQAKVPVAVHFD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIvtEADSAYTNPDAAKL 163
Cdd:PRK06806  83 HGMTFEKIKEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSE--DIEMLLTSTTEAKR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 164 FVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGA 243
Cdd:PRK06806 161 FAEETDVDALAVAIGNAHGMYNGDPNLRFDRLQEINDVVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNSVITA 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 518384895 244 IKEFFLANPSANDPRRYMTPGKDAMAKVVEHkIKICGSANR 284
Cdd:PRK06806 241 VNNLVLNTPYSDYFTYHQDVIKAAYENVKKH-MQIFGSENK 280
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
6-282 1.21e-70

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 221.37  E-value: 1.21e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   6 STKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQ-TDIPIALHLDH 84
Cdd:PRK09196   5 SLRQLLDHAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKYAGEPFLRHLILAAVEEyPHIPVVMHQDH 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  85 HENVATIKTDIDAGFRSAMIDASHE-------SFEKNIEIVKEVVAYAHKYDTTVEAELGKL------VGQEDDLIVTEA 151
Cdd:PRK09196  85 GNSPATCQRAIQLGFTSVMMDGSLKadgktpaSYEYNVDVTRKVVEMAHACGVSVEGELGCLgsletgMGGEEDGHGAEG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 152 ----DSAYTNPDAAKLFVEATGIDSLAIAIGTAHGLYKGTPK-----LDFDRLQQIRSKvdIP---LVLHGASDVPDEL- 218
Cdd:PRK09196 165 klshDQLLTDPEEAADFVKKTQVDALAIAIGTSHGAYKFTRKptgdvLAIDRIKEIHAR--LPnthLVMHGSSSVPQELl 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 219 --------------------VQKAIAMGICKVNVATDLKIPFSGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKI 278
Cdd:PRK09196 243 diineyggdmpetygvpveeIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAENPSEFDPRKYLKPAMEAMKKICKARYEA 322


                 ....
gi 518384895 279 CGSA 282
Cdd:PRK09196 323 FGTA 326
gatY PRK07998
class II aldolase;
11-278 2.51e-70

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 218.48  E-value: 2.51e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  11 LLNAQKENYAV-PAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLDHHENVA 89
Cdd:PRK07998   9 LLDRIQEKHVLaGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLHLDHGKTFE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  90 TIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLiVTEADsAYTNPDAAKLFVEATG 169
Cdd:PRK07998  89 DVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDDH-VSEAD-CKTEPEKVKDFVERTG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 170 IDSLAIAIGTAHGLYKgTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIKEFFL 249
Cdd:PRK07998 167 CDMLAVSIGNVHGLED-IPRIDIPLLKRIAEVSPVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDLRKAFITTVGKAYV 245

                        250       260
                 ....*....|....*....|....*....
gi 518384895 250 ANPSANDPRRYMTPGKDAMAKVVEHKIKI 278
Cdd:PRK07998 246 NNHNEANLARVMAKAKQAVEEDVYSKIKM 274
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
4-284 4.24e-68

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 213.07  E-value: 4.24e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQTDIPIALHLD 83
Cdd:PRK06801   3 LISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLESLVEAVKFEAARHDIPVVLNLD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  84 HHENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSA-YTNPDAAK 162
Cdd:PRK06801  83 HGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSAkFTDPQLAR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 163 LFVEATGIDSLAIAIGTAHGLYKGTPKLDFDRLQQIRSKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSG 242
Cdd:PRK06801 163 DFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAALA 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 518384895 243 AI-KEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK06801 243 AVeQRMTHRHAIYDEFAELLLGIEEAISDTVAQQMRIFGSAGQ 285
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
5-282 1.29e-63

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 203.47  E-value: 1.29e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   5 LSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCEYLIAMAQVAARQ-TDIPIALHLD 83
Cdd:PRK13399   4 ITLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAGDAMLRHMVLAAAEMyPDIPICLHQD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  84 HHENVATIKTDIDAGFRSAMIDASHE-------SFEKNIEIVKEVVAYAHKYDTTVEAELGKL------VGQEDDLIVTE 150
Cdd:PRK13399  84 HGNSPATCQSAIRSGFTSVMMDGSLLadgktpaSYDYNVDVTRRVTEMAHAVGVSVEGELGCLgsletgEAGEEDGVGAE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 151 A----DSAYTNPDAAKLFVEATGIDSLAIAIGTAHGLYKGTPK-----LDFDRLQQIRSKV-DIPLVLHGASDVPDEL-- 218
Cdd:PRK13399 164 GklshDQMLTDPDQAVDFVQRTGVDALAIAIGTSHGAYKFTRKpdgdiLAIDRIEEIHARLpNTHLVMHGSSSVPQELqe 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 219 -------------------VQKAIAMGICKVNVATDLKIPFSGAIKEFFLANPSANDPRRYMTPGKDAMAKVVEHKIKIC 279
Cdd:PRK13399 244 iinayggkmketygvpveeIQRGIKHGVRKVNIDTDIRLAMTGAIRKVLAEHPSEFDPRKALKPAMKAMTALCKQRFEAF 323


                 ...
gi 518384895 280 GSA 282
Cdd:PRK13399 324 GTA 326
PLN02858 PLN02858
fructose-bisphosphate aldolase
 6-284 1.47e-62

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 213.17  E-value: 1.47e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895    6 STKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYANCeYLIAMAQVAARQTDIPIALHLDHH 85
Cdd:PLN02858 1101 STKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALKQGGI-PLVSCCIAAAEQASVPITVHFDHG 1179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   86 ENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIVTEADSAYTNPDAAKLFV 165
Cdd:PLN02858 1180 TSKHELLEALELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGTEDGLTVEEYEAKLTDVDQAKEFI 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  166 EATGIDSLAIAIGTAHGLYKGT-PKLDFDRLQQIR---SKVDIPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFS 241
Cdd:PLN02858 1260 DETGIDALAVCIGNVHGKYPASgPNLRLDLLKELRalsSKKGVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRTAYM 1339

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 518384895  242 GAIKEfflanPSANDPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PLN02858 1340 EALSS-----PKKTDLIDVMSAAKEAMKAVVAEKLRLFGSAGK 1377
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 4-284 4.32e-54

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 177.39  E-value: 4.32e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   4 ILSTKQMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIAATPSTVTYAN----CEYLIAMAqVAARQTDIPIA 79
Cdd:PRK07315   3 IVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGgykvCKNLIENL-VESMGITVPVA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  80 LHLDHHENVATIKTdIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVGQEDDLIvteADSAYTNPD 159
Cdd:PRK07315  82 IHLDHGHYEDALEC-IEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGII---GKGELAPIE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 160 AAKLFVEaTGIDSLAIAIGTAHGLYKGTPK-LDFDRLQQIRSKV-DIPLVLHGASDVPDELVQKAIAMGICKVNVATDLK 237
Cdd:PRK07315 158 DAKAMVE-TGIDFLAAGIGNIHGPYPENWEgLDLDHLEKLTEAVpGFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQ 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 518384895 238 IPFSGAIKEfFLANPSAN----------DPRRYMTPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK07315 237 IAFANATRK-FARDYEANeaeydkkklfDPRKFLAPGVKAIQASVEERIDVFGSANK 292
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 9-284 6.61e-33

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 123.37  E-value: 6.61e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895   9 QMLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIaatpsTVTYANCEYL-----------------IAMAQ--- 68
Cdd:PRK09197  11 EMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVII-----QFSNGGAAFIagkgvkddgqgaavlgaIAGAKhvh 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  69 VAARQTDIPIALHLDH--HENVATIKTDIDAG-----------FRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAE 135
Cdd:PRK09197  86 EVAEHYGVPVILHTDHcaKKLLPWIDGLLDAGekhfaaggkplFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTLEIE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 136 LGKLVGQEDDLIVTEADSA--YTNPDAAKLFVEATGIDS----LAIAIGTAHGLYK-GTPKLDFDRLQQIRSKVD----- 203
Cdd:PRK09197 166 LGVTGGEEDGVDNSHEDNSklYTQPEDVLYAYEALGKISgrftIAASFGNVHGVYKpGNVKLRPEILKDSQEYVSkkfgl 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 204 ----IPLVLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIKEFFLA----------NPSAN--------DPRRYM 261
Cdd:PRK09197 246 pakpFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKnydylqgqvgNPEGEdkpnkkyyDPRVWL 325

                        330       340
                 ....*....|....*....|...
gi 518384895 262 TPGKDAMAKVVEHKIKICGSANR 284
Cdd:PRK09197 326 RAAEASMAARLEEAFEDLNSIGV 348
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 10-285 1.94e-31

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 119.40  E-value: 1.94e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  10 MLLNAQKENYAVPAFNIHNMETLQVVVETASKMHSPLIIA------------ATPSTVTYANCEYLIAMA---QVAARQT 74
Cdd:cd00946    7 LFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQfsnggaafyagkGLKNEKQKASIAGAIAAAhhvRSMAEHY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895  75 DIPIALHLDH-------------HENVATIKTDIDAGFRSAMIDASHESFEKNIEIVKEVVAYAHKYDTTVEAELGKLVG 141
Cdd:cd00946   87 GVPVVLHTDHcakkllpwfdgllEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEMEIGITGG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 142 QEDDLIVTEADSA--YTNP-DAAKLFVEATGID---SLAIAIGTAHGLYKG-----TPKLDFDRLQQIRSKV----DIPL 206
Cdd:cd00946  167 EEDGVDNSGVDNAelYTQPeDVWYVYEALSKISpnfSIAAAFGNVHGVYKPgnvklQPEILGEHQDYVREKLgladDKPL 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518384895 207 --VLHGASDVPDELVQKAIAMGICKVNVATDLKIPFSGAIKEFFLAN----------------PSAN--DPRRYMTPGKD 266
Cdd:cd00946  247 yfVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNedylqgqignpegpdkPNKKyyDPRVWLREGEK 326

                        330
                 ....*....|....*....
gi 518384895 267 AMAKVVEHKIKICGSANRY 285
Cdd:cd00946  327 SMVARVKKAFEDLNSVNKL 345
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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