|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
109-483 |
8.42e-89 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 277.04 E-value: 8.42e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 109 LGGFILAIAMERWDLHTRIALTIISSIGTSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANalkteadsDE 188
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALG--------SE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 189 SIQKFERSLVLGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFKFIaFRHDMK 268
Cdd:COG0471 73 KRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRL-LPPEIK 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 269 TLPGGQKVIKDKLDALGKIKYEEKVVFVVFLLASFLWISREFLLskwaftelVADGTIAMFVSILLFLIpakhqhkRILD 348
Cdd:COG0471 152 EVPGSKEVIREELAELGPLSRREKIALAIFALTVLLWITGSLHG--------IPIAVVALLGAVLLLLT-------GVLT 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 349 WS-VAKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLT-LLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILA 426
Cdd:COG0471 217 WKdAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLpLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAI 296
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 517996080 427 TLSVAIDVHPLLLMAPAAMAANCAYMLPVGTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:COG0471 297 SLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNL 353
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
57-483 |
1.93e-60 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 203.59 E-value: 1.93e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 57 LAITAWIAIWWITEAIPIPATSLLPLVLLPLGHVMNSATVSAQYGNDIIYLFLGGFILAIAMERWDLHTRIALTIISSIG 136
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 137 TSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIikeanALKTEADSDesiqkferSLVLGIGYAGTIGGLGTLIGT 216
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGL-----AAKLDISPS--------RLLMPLAFAASIGGMLTLIGT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 217 PPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFkfiafrhdmktlpggqkvikdkldalgkikyeekvVFV 296
Cdd:cd01115 148 PPNLVASGYLESLGGQGFSFFEFTPIGLPLLIIGLLYLWFIF-----------------------------------RLA 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 297 VFLLASFLWIsreflLSKWAFTELVADGTIAMFVSILLFLipakhqhKRILDWSVAKELPWGVLILFGGGLALAKGIQQS 376
Cdd:cd01115 193 VLIITIVLLA-----ALAAITGLLPVSVAIAIGAIVLVFG-------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALESS 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 377 GLAAWLGEQLT-LLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILATLSVAIDVHPLLLMAPAAMAANCAYMLPV 455
Cdd:cd01115 261 GAAALIAEALIsLLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPV 340
|
410 420
....*....|....*....|....*...
gi 517996080 456 GTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:cd01115 341 GTPPNAIVLGPGGYKFSDFAKVGLPLSI 368
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
46-483 |
5.76e-56 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 193.33 E-value: 5.76e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 46 PDDLAFKGVYVLAITAWIAIWWITEAIPIPATSLLPLVLL-----PLGHVMNSATVSAqYGNDIIYLFLGGFILAIAMER 120
Cdd:TIGR00785 3 PDGLNSGAWLLLAIFVAAIVGWILEPLPLPVTALLAIPIIavllgVLSAFKFKNALSG-FADPTIWLFFGAFILATALVK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 121 WDLHTRIALTIISSIGTST-GRILLGFMVATGGLSMFVSNTA-AVMIMIPIGLAIikeANALKTEADSDESiqKFERSLV 198
Cdd:TIGR00785 82 TGLGKRIAYKLVGKMGGTTlGLGYFLVFLETLLAPMWPSNTArAGGILLPIIKSL---LPLLGSKPEKSPR--KIGKYLM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 199 LGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFkFIAFRHDMKTLPGGQKVIK 278
Cdd:TIGR00785 157 LGIAYSASIGSSGFLTGSAPNALAAGILSKILGIQISWGDWFLAGLPLGIILLLLVPLLL-YVLFPPELKLKDEVDLWAK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 279 DKLDALGKIKYEEKVVFVVFLLASFLWISREFLlskwafteLVADGTIAMFVSILLFLIpakhqhkRILDWSVAKELP-- 356
Cdd:TIGR00785 236 EELEEMGPMSFREKALLGIFLLALLLWIFGGSL--------GINASVVALLAVVLMLFL-------GIVTWKDIQKNKva 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 357 WGVLILFGGGLALAKGIQQSGLAAWLGEQLT--LLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILATLSVAIDV 434
Cdd:TIGR00785 301 WNTLILFGGLIGLAGGLKKSGFIKWFSEKLVgiLDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGI 380
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 517996080 435 HPLLLMAPAAMAANCA-YMLPVGTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:TIGR00785 381 PLELLALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGI 430
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
29-483 |
5.25e-52 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 183.34 E-value: 5.25e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 29 GLVLGPLLFALILLFVRPDDLAFKGVYVLAITAWIAIWWITEAIPIPATSLLPLVLLPLGHVMNSAT----VSAQYGNDI 104
Cdd:pfam00939 6 KLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKalswALSGFSSTT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 105 IYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRilLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALKTEA 184
Cdd:pfam00939 86 TWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRTLG--LGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAFGSD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 185 DSDESIQKFERSLVLGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFkFIAFR 264
Cdd:pfam00939 164 PEKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSILGVTITWASWFLAAIPPGVILLLLAPLLL-YVLYP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 265 HDMKTLPGGQKVIKDKLDALGKIKYEEKVVFVVFLLASFLWISREFLlskwafteLVADGTIAMFVSILLFLIpakhqhk 344
Cdd:pfam00939 243 PEIKSVPDAKAIAKTELKELGPMTFREKALLGLFVLLLLLWIFGGSL--------NIDATTVAIIGLALMLLL------- 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 345 RILDWS--VAKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLTLLKGVSPIIIVVVITVFILFLT--EITSNTATATM 420
Cdd:pfam00939 308 RILDWKdiVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSGFSPAMAFIIILSLFYLShyLFASATAHTAA 387
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517996080 421 ILPILATLSVAIDVHPLLLMAPAAMAANC--AYMLPVGTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:pfam00939 388 MLPIFAAVAQAIPGAPPLLAALLLGFAISlgGFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTI 452
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
109-483 |
8.42e-89 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 277.04 E-value: 8.42e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 109 LGGFILAIAMERWDLHTRIALTIISSIGTSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANalkteadsDE 188
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALG--------SE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 189 SIQKFERSLVLGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFKFIaFRHDMK 268
Cdd:COG0471 73 KRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRL-LPPEIK 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 269 TLPGGQKVIKDKLDALGKIKYEEKVVFVVFLLASFLWISREFLLskwaftelVADGTIAMFVSILLFLIpakhqhkRILD 348
Cdd:COG0471 152 EVPGSKEVIREELAELGPLSRREKIALAIFALTVLLWITGSLHG--------IPIAVVALLGAVLLLLT-------GVLT 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 349 WS-VAKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLT-LLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILA 426
Cdd:COG0471 217 WKdAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLpLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAI 296
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 517996080 427 TLSVAIDVHPLLLMAPAAMAANCAYMLPVGTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:COG0471 297 SLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNL 353
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
57-483 |
1.93e-60 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 203.59 E-value: 1.93e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 57 LAITAWIAIWWITEAIPIPATSLLPLVLLPLGHVMNSATVSAQYGNDIIYLFLGGFILAIAMERWDLHTRIALTIISSIG 136
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 137 TSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIikeanALKTEADSDesiqkferSLVLGIGYAGTIGGLGTLIGT 216
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGL-----AAKLDISPS--------RLLMPLAFAASIGGMLTLIGT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 217 PPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFkfiafrhdmktlpggqkvikdkldalgkikyeekvVFV 296
Cdd:cd01115 148 PPNLVASGYLESLGGQGFSFFEFTPIGLPLLIIGLLYLWFIF-----------------------------------RLA 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 297 VFLLASFLWIsreflLSKWAFTELVADGTIAMFVSILLFLipakhqhKRILDWSVAKELPWGVLILFGGGLALAKGIQQS 376
Cdd:cd01115 193 VLIITIVLLA-----ALAAITGLLPVSVAIAIGAIVLVFG-------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALESS 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 377 GLAAWLGEQLT-LLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILATLSVAIDVHPLLLMAPAAMAANCAYMLPV 455
Cdd:cd01115 261 GAAALIAEALIsLLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPV 340
|
410 420
....*....|....*....|....*...
gi 517996080 456 GTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:cd01115 341 GTPPNAIVLGPGGYKFSDFAKVGLPLSI 368
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
46-483 |
5.76e-56 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 193.33 E-value: 5.76e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 46 PDDLAFKGVYVLAITAWIAIWWITEAIPIPATSLLPLVLL-----PLGHVMNSATVSAqYGNDIIYLFLGGFILAIAMER 120
Cdd:TIGR00785 3 PDGLNSGAWLLLAIFVAAIVGWILEPLPLPVTALLAIPIIavllgVLSAFKFKNALSG-FADPTIWLFFGAFILATALVK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 121 WDLHTRIALTIISSIGTST-GRILLGFMVATGGLSMFVSNTA-AVMIMIPIGLAIikeANALKTEADSDESiqKFERSLV 198
Cdd:TIGR00785 82 TGLGKRIAYKLVGKMGGTTlGLGYFLVFLETLLAPMWPSNTArAGGILLPIIKSL---LPLLGSKPEKSPR--KIGKYLM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 199 LGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFkFIAFRHDMKTLPGGQKVIK 278
Cdd:TIGR00785 157 LGIAYSASIGSSGFLTGSAPNALAAGILSKILGIQISWGDWFLAGLPLGIILLLLVPLLL-YVLFPPELKLKDEVDLWAK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 279 DKLDALGKIKYEEKVVFVVFLLASFLWISREFLlskwafteLVADGTIAMFVSILLFLIpakhqhkRILDWSVAKELP-- 356
Cdd:TIGR00785 236 EELEEMGPMSFREKALLGIFLLALLLWIFGGSL--------GINASVVALLAVVLMLFL-------GIVTWKDIQKNKva 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 357 WGVLILFGGGLALAKGIQQSGLAAWLGEQLT--LLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILATLSVAIDV 434
Cdd:TIGR00785 301 WNTLILFGGLIGLAGGLKKSGFIKWFSEKLVgiLDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGI 380
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 517996080 435 HPLLLMAPAAMAANCA-YMLPVGTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:TIGR00785 381 PLELLALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGI 430
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
29-483 |
5.25e-52 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 183.34 E-value: 5.25e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 29 GLVLGPLLFALILLFVRPDDLAFKGVYVLAITAWIAIWWITEAIPIPATSLLPLVLLPLGHVMNSAT----VSAQYGNDI 104
Cdd:pfam00939 6 KLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKalswALSGFSSTT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 105 IYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRilLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALKTEA 184
Cdd:pfam00939 86 TWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRTLG--LGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAFGSD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 185 DSDESIQKFERSLVLGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFkFIAFR 264
Cdd:pfam00939 164 PEKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSILGVTITWASWFLAAIPPGVILLLLAPLLL-YVLYP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 265 HDMKTLPGGQKVIKDKLDALGKIKYEEKVVFVVFLLASFLWISREFLlskwafteLVADGTIAMFVSILLFLIpakhqhk 344
Cdd:pfam00939 243 PEIKSVPDAKAIAKTELKELGPMTFREKALLGLFVLLLLLWIFGGSL--------NIDATTVAIIGLALMLLL------- 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 345 RILDWS--VAKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLTLLKGVSPIIIVVVITVFILFLT--EITSNTATATM 420
Cdd:pfam00939 308 RILDWKdiVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSGFSPAMAFIIILSLFYLShyLFASATAHTAA 387
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517996080 421 ILPILATLSVAIDVHPLLLMAPAAMAANC--AYMLPVGTPPNAIVFGTGKIQIKEMAVKGFVMNL 483
Cdd:pfam00939 388 MLPIFAAVAQAIPGAPPLLAALLLGFAISlgGFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTI 452
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
64-435 |
4.99e-38 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 142.45 E-value: 4.99e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 64 AIWWITEAIPIPATSLLPLVLLPLGHVMNSATVSAQYGNDIIYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRIL 143
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 144 LGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALKteadsdesiqkfeRSLVLGIGYAGTIGGLGTLIGTPPLIILK 223
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPP-------------SPLLIALAFAANIGGTATPIGDPPNIIIA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 224 GQYATNFgGELSFAKWMIVGVPTVILLLFLAWLYFKFIAFRHDMKtlpggqkviKDKLDALGKIKYEEKVVFVVFLLASF 303
Cdd:pfam03600 148 SALGLSF-GDFGFFMFPPVGVALLLVGLLPLLLIFRKLLPVRKEE---------EAELEELRKRAIKDKLLLAISALVLA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 304 LWISREFLLSKWAFTELVADGTIamfvsillflipakhqhKRILDWSVAKELPWGVLILFGGGLALAKGIQQSGLAAWLG 383
Cdd:pfam03600 218 LVILGFLLLSVLALAGALLLLLT-----------------GVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALA 280
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 517996080 384 EQLTLLKGvsPIIIVVVITVFILFLTEITSNTATATMILPILATLSVAIDVH 435
Cdd:pfam03600 281 DALGGLSG--LLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLG 330
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
64-483 |
5.84e-36 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 137.77 E-value: 5.84e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 64 AIWWITEAIPIPATSLLPLVLLPLGHVMNSATVSAQYGNDIIYLFLGGFILAIAMERWDLHTRIAlTIISSIGTSTGRIL 143
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLA-AKLARASKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 144 LGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALKTeadsdesiqkfeRSLVLGIGYAGTIGGLGTLIGTPPLIILK 223
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPP------------VPLLLALAFAANIGGAATPIGNPPNLIIA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 224 GQYATNFGGELSFAKWMIVGVPTVILLLFLAWLYFKFIafrhdmktlpggqKVIKDKLDALGKIKYEEKVVFVVFLLASF 303
Cdd:cd00625 148 SLSGLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLL-------------LPDEDKLTVLAEPLPARPLLKKFLLLALL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 304 LwisreFLLSKWAFTELVADGTIAMFVSILLFLIPAKhqhkRILDWSVAKELPWGVLILFGGGLALAKGIQQSGLAAWLG 383
Cdd:cd00625 215 L-----LLLFVLLFFFLIPLGLIALLGALLLLLLLVR----GLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLA 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 384 EQLTLLKGVSPIIIVVVITVFILFLTEITSNTATATMILPILATLS-----VAIDVHPLLLMAPAAMAANCAYMLPVGTP 458
Cdd:cd00625 286 ELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAppepaWLALALGSTLGGNLTLIGSLANLIPLGAA 365
|
410 420
....*....|....*....|....*
gi 517996080 459 PNAIVfgtgKIQIKEMAVKGFVMNL 483
Cdd:cd00625 366 ENAGV----GISFGEFLKVGLPLTL 386
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
103-435 |
2.78e-16 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 80.94 E-value: 2.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 103 DIIYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALkt 182
Cdd:COG1055 54 NTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN-- 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 183 eadsdesiqkfERSLVLGIGYAGTIGGLGTLIGTPPLIILkGQYatnfgGELSFAKWMIVGVPTVILLLFLAWLYFKFIa 262
Cdd:COG1055 132 -----------PVPFLIAIVFAANIGGAATPIGNPTNIMI-ASA-----GGLSFLDFLANLFPPSLVSLLVTLLVLYLL- 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 263 FRHDMKTLPGGQKVIKDKLdalgKIKYEEKVVFVVFLLASFLWISREFLlskwafteLVADGTIAMFVSILLFLIpAKHQ 342
Cdd:COG1055 194 FRKELPAAPDLEDDPKEAI----KDRRLLRISLLVLALLLVGFVLHSFL--------GLPPALIALLGAAVLLLL-ARVD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 343 HKRILdwsvaKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLTLLKGVSPIIIVVVITVFILFLTEITSNTATATMIL 422
Cdd:COG1055 261 VREVL-----KKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALL 335
|
330
....*....|...
gi 517996080 423 PILATLSVAIDVH 435
Cdd:COG1055 336 PLIPDLGATGNPE 348
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
95-435 |
5.93e-11 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 64.20 E-value: 5.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 95 TVSAQYGNDIIYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAII 174
Cdd:cd01116 40 TIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLC 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 175 KEANalkteadsdesiqKFERSLVLGIGYAGTIGGLGTLIGTPPLIILkGQyatnfGGELSFAKWMIVGVPTVILLLFLA 254
Cdd:cd01116 120 EVLG-------------LNPVPVLISEVIAANIGGAATLIGDPPNIMI-GS-----AAGLTFNDFLLHMLPSVVLALVVT 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 255 WLYFKFIaFRHDMKTLPGGQkvikDKLDALGKIKYEEKVVFVVFLLASFLWISREFLLSKWAFTELvadGTIAMFVSILL 334
Cdd:cd01116 181 FILLYFL-YRNILKAREEDV----LALAELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPLGVSL---GWIALLGALLL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 335 FLIPAKHQHKRILdwsvaKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLTLLKGVSPIIIVVVITVFILFLTEITSN 414
Cdd:cd01116 253 LLLADKLDFEDVL-----SRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILWISALLSAFIDN 327
|
330 340
....*....|....*....|.
gi 517996080 415 TATATMILPILATLSVAIDVH 435
Cdd:cd01116 328 IPVTATMIPIVKDLASQLGIP 348
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
103-430 |
2.30e-10 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 62.30 E-value: 2.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 103 DIIYLFLGGFILAIAMERWDLHTRIALTIISSIGTStgRILLGFMV-ATGGLSMFVSNTAAVMIMIPIGLAIIKEANALk 181
Cdd:cd01117 42 DTIILLFGLMVVSAALELSGFFDALGSRILVKAGSP--RRLLFLLVlLSGILSALLTNDTACLVFTPIVLELARVAGLP- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 182 teadsdesiqkfERSLVLGIGYAGTIGGLGTLIGTPPLIILKGQYATNFGGelsFAKWMI-VGVPTVILLLFLAWLYFKF 260
Cdd:cd01117 119 ------------PIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPF---FLAAMApLALLGLLLLLILLLVLFPG 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 261 iafrhdmktlpggqKVIKDKLDALGKIKYEEKVVFVVFLLASFLWISREFLlskwAFTELVADGTIAMFVSILLFLIpak 340
Cdd:cd01117 184 --------------ELKGLPLDKATKEEGVGARKLAVKLLVLILLLLVAFL----ALLGVIPLWTAALVAAVLLLLT--- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 341 hqhkRILDWSVAKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLTLLKGvspiiiVVVITVFILFLTEITSNTATATM 420
Cdd:cd01117 243 ----RLKPRRVLKKVDWGLLLFFAGLFILVGGFAQGLPLEGLSRLLPLLDS------VLSLFLVSIGLSQLISNVPAVLL 312
|
330
....*....|
gi 517996080 421 ILPILATLSV 430
Cdd:cd01117 313 LLPFLPSADE 322
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
103-263 |
7.69e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 51.28 E-value: 7.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 103 DIIYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALkt 182
Cdd:COG1055 271 STLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPE-- 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 183 eadsdesiqkferSLVLGIGYAGTIGGLGTLIGTPPLIILKGQYATNfGGELSFAKWMIVGVPTVILLLFLAWLYFKFIA 262
Cdd:COG1055 349 -------------PLWLALALGATLGGNLTPIGSAANVIVLGIAEKK-GIKISFGEFLKVGLPLTLLTLLIALLYLLLLY 414
|
.
gi 517996080 263 F 263
Cdd:COG1055 415 F 415
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
28-253 |
9.61e-07 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 51.05 E-value: 9.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 28 IGLVLGPLLFALILLFVRpddlafKGVYVLAITAWIAIWWITEAIPIPATSLLPLVLLPLGHVMNSATVSAQYGNDIIYL 107
Cdd:cd01115 173 IGLPLLIIGLLYLWFIFR------LAVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 108 FLGGFILAIAMERWDLHTRIALTIISSIGTSTG-RILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANALKteads 186
Cdd:cd01115 247 FAGGIPLGKALESSGAAALIAEALISLLGGLPPfAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPP----- 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517996080 187 desiqkfeRSLVLGIGyAGTIGGLGTLIGTPP--LIILKGQYatnfggelSFAKWMIVGVPTVILLLFL 253
Cdd:cd01115 322 --------EALLLAVA-IGASCAFMLPVGTPPnaIVLGPGGY--------KFSDFAKVGLPLSILSLVV 373
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
28-260 |
3.34e-05 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 45.92 E-value: 3.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 28 IGLVLGPLLFALILLFVRPDDLAFKGV-------------------YVLAITAWIAIWWITEA---IPIPATSLLPLVLL 85
Cdd:COG0471 130 VALVGLLLLWLVLYRLLPPEIKEVPGSkevireelaelgplsrrekIALAIFALTVLLWITGSlhgIPIAVVALLGAVLL 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 86 PLGHVMNSATVSAQYGNDIIYLFLGGFILAIAMERWDLHTRIALTIISSI-GTSTGRILLGFMVATGGLSMFVSNTAAVM 164
Cdd:COG0471 210 LLTGVLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLgGLSPLLLLLLLALLTLLLTEFASNTATAA 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 165 IMIPIGLAIikeANALKTEAdsdesiqkfeRSLVLGIGYAGTIGGLgTLIGTPPLIILkgqYATnfgGELSFAKWMIVGV 244
Cdd:COG0471 290 LLLPIAISL---AQALGVNP----------LPLALAVAFAASCAFL-LPVGTPPNAIV---YGS---GYYKFKDFLKVGL 349
|
250 260
....*....|....*....|
gi 517996080 245 P----TVILLLFLAWLYFKF 260
Cdd:COG0471 350 PlnliGLVVLLLLGPLWWPL 369
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
101-389 |
3.37e-04 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 43.02 E-value: 3.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 101 GNDIIYLFLGGFILAIAMERWDLHTRIALTIISSIGTSTGRILLGFMVATGGLSMFVSNTAAVMIMIPIGLAIIKEANAL 180
Cdd:cd01118 51 VWDVTLTLIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAK 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 181 KteadsdesiqKFERSLVLGIGYAGTIGGLGTLIGTPPLIILkgqyATNFG-GELSFAKWMIVGVPTVIL--LLFLAWLY 257
Cdd:cd01118 131 K----------NRTLPFLYACAFIADAASLPLPISNLVNIVT----AGYFGiGFTEYAALMFLPSIVSILatYVVLYLFF 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517996080 258 FKFIAFRHDMKTLPGGQKVIKDKLDALgkikyeEKVVFVVFLLASFLWIsrEFLLSKWAFtelvadgtIAMFVSILLFLI 337
Cdd:cd01118 197 RRALPKRLETASVKKPSLAIKDPLLFG------LAWTLLVLLVVSAFGV--DILLIPPSF--------IAGVLALIFLLL 260
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 517996080 338 PAKHQHKRILDwsVAKELPWGVLILFGGGLALAKGIQQSGLAAWLGEQLTLL 389
Cdd:cd01118 261 ARRGGAINPLK--VLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWL 310
|
|
| |
