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Conserved domains on  [gi|517259200|ref|WP_018448018|]
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MULTISPECIES: DNA polymerase III subunit gamma/tau [Rhizobium]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11483564)

DNA polymerase III subunit gamma/tau (DnaX) is involved in cell cycle control

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
8-622 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 1009.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   8 SKDAASTGTGYRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEID- 86
Cdd:PRK09111   1 APDAAAAATPYRVLARKYRPQTFDDL-IGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPDGDg 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  87 KPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEP 166
Cdd:PRK09111  80 GPTIDLCGVGEHCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 167 PEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIA 246
Cdd:PRK09111 160 PPHVKFIFATTEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIA 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 247 HGAGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPS 326
Cdd:PRK09111 240 HGAGEVTAEAVRDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAEDPS 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 327 LSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLAEFSGDNSGPRP 406
Cdd:PRK09111 320 LSEAERTRGAEFAKKLSMRVLSRLWQMLLKGIEEVQGAPRPLAAAEMVLIRLAYAADLPTPDEALRRLQEGPPSPGGGGG 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 407 AAPPSgngggngtRVSYQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAealkPLVPVNSVNDIVN 486
Cdd:PRK09111 400 GPPGG--------GGAPGAPAAAAAPGAAAAAPAAGGPAAALAAVPDAAAAAAAPPAPAAAPQ----PAVRLNSFEDIVA 467
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 487 LATEKRDPKLKAMVRTFLRPVRIEAGRLDVSLAPGAPTTLLNELAVKLKEWTGIHWIVSLSRDEGQPTLVEAEARTREQH 566
Cdd:PRK09111 468 LAEEKRDIKLKAAVERDVRLVRFEPGRLEFALAPGAPRDLAQRLARKLEEWTGRRWVVSVSREGGQPTLAEQEAAAREER 547
                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 567 VIDARQDPDVAAILAHFPGAKIIDVRVRapepeEEGEATPPAAAESEEGDILPGDD 622
Cdd:PRK09111 548 EAAAEADPLVAAVLAAFPGAKIVDVRDL-----APEAAEEEPAAEAEDPDALPDDD 598
 
Name Accession Description Interval E-value
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
8-622 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 1009.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   8 SKDAASTGTGYRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEID- 86
Cdd:PRK09111   1 APDAAAAATPYRVLARKYRPQTFDDL-IGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPDGDg 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  87 KPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEP 166
Cdd:PRK09111  80 GPTIDLCGVGEHCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 167 PEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIA 246
Cdd:PRK09111 160 PPHVKFIFATTEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIA 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 247 HGAGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPS 326
Cdd:PRK09111 240 HGAGEVTAEAVRDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAEDPS 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 327 LSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLAEFSGDNSGPRP 406
Cdd:PRK09111 320 LSEAERTRGAEFAKKLSMRVLSRLWQMLLKGIEEVQGAPRPLAAAEMVLIRLAYAADLPTPDEALRRLQEGPPSPGGGGG 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 407 AAPPSgngggngtRVSYQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAealkPLVPVNSVNDIVN 486
Cdd:PRK09111 400 GPPGG--------GGAPGAPAAAAAPGAAAAAPAAGGPAAALAAVPDAAAAAAAPPAPAAAPQ----PAVRLNSFEDIVA 467
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 487 LATEKRDPKLKAMVRTFLRPVRIEAGRLDVSLAPGAPTTLLNELAVKLKEWTGIHWIVSLSRDEGQPTLVEAEARTREQH 566
Cdd:PRK09111 468 LAEEKRDIKLKAAVERDVRLVRFEPGRLEFALAPGAPRDLAQRLARKLEEWTGRRWVVSVSREGGQPTLAEQEAAAREER 547
                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 567 VIDARQDPDVAAILAHFPGAKIIDVRVRapepeEEGEATPPAAAESEEGDILPGDD 622
Cdd:PRK09111 548 EAAAEADPLVAAVLAAFPGAKIVDVRDL-----APEAAEEEPAAEAEDPDALPDDD 598
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
18-379 3.51e-159

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 460.50  E-value: 3.51e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   18 YRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGE 97
Cdd:TIGR02397   1 YQVLARKYRPQTFED-VIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPC----NECE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:TIGR02397  76 SCKEINSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATT 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:TIGR02397 156 EPHKIPATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDV 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPdaANDPSLSEVERTKAAE 337
Cdd:TIGR02397 236 NELLGLVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTP--SNLLAVLESEQEFLKE 313
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 517259200  338 FAKGVAVTTLSRIWQMLLKGIPETEGS--SRTagAAEMVLIRLA 379
Cdd:TIGR02397 314 LALKLSLEFLLRLLDILLEALKDLRFSndPRI--WLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
27-380 1.18e-155

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 450.80  E-value: 1.18e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  27 PKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPtidlrtPGE--HCQAIME 104
Cdd:COG2812    6 PQTFDDV-VGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEP------CGEceSCRAIAA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 105 GRHVDVIEMDA-ASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVP 183
Cdd:COG2812   79 GSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 184 ITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAgvvqaeavrgmlgL 263
Cdd:COG2812  159 PTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFGL-------------L 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 264 ADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAanDPSLSEVERTKAAEFAKGVA 343
Cdd:COG2812  226 DRRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDA--ELLVNEDERERLQELARRLS 303
                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 517259200 344 VTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAH 380
Cdd:COG2812  304 PERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
252-394 7.74e-58

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 190.94  E-value: 7.74e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  252 VQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSEVE 331
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPDAADDLLLPEEE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517259200  332 RTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRL 394
Cdd:pfam12169  81 RARLAELAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLRLAYAASLPPPEELLRRL 143
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
198-262 1.40e-22

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 91.41  E-value: 1.40e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517259200 198 ISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRGMLG 262
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
55-198 3.09e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.84  E-value: 3.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200    55 QAYMLTGVRGVGKTTTARILARALNYKTSEIdkptIDLRTPGEHCQAiMEGRHVDVIEMDAASHTGIDDIREIIEQVRYR 134
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGPPGGGV----IYIDGEDILEEV-LDQLLLIIVGGKKASGSGELRLRLALALARKL 77
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517259200   135 pvsaRYKVYIIDEVHMLSTQAFNGLL-------KTLEEPPEHVKFIFATTEIRKVPITVLSR---CQRFDLRRI 198
Cdd:smart00382  78 ----KPDVLILDEITSLLDAEQEALLllleelrLLLLLKSEKNLTVILTTNDEKDLGPALLRrrfDRRIVLLLI 147
 
Name Accession Description Interval E-value
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
8-622 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 1009.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   8 SKDAASTGTGYRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEID- 86
Cdd:PRK09111   1 APDAAAAATPYRVLARKYRPQTFDDL-IGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPDGDg 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  87 KPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEP 166
Cdd:PRK09111  80 GPTIDLCGVGEHCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 167 PEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIA 246
Cdd:PRK09111 160 PPHVKFIFATTEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIA 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 247 HGAGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPS 326
Cdd:PRK09111 240 HGAGEVTAEAVRDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAEDPS 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 327 LSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLAEFSGDNSGPRP 406
Cdd:PRK09111 320 LSEAERTRGAEFAKKLSMRVLSRLWQMLLKGIEEVQGAPRPLAAAEMVLIRLAYAADLPTPDEALRRLQEGPPSPGGGGG 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 407 AAPPSgngggngtRVSYQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAealkPLVPVNSVNDIVN 486
Cdd:PRK09111 400 GPPGG--------GGAPGAPAAAAAPGAAAAAPAAGGPAAALAAVPDAAAAAAAPPAPAAAPQ----PAVRLNSFEDIVA 467
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 487 LATEKRDPKLKAMVRTFLRPVRIEAGRLDVSLAPGAPTTLLNELAVKLKEWTGIHWIVSLSRDEGQPTLVEAEARTREQH 566
Cdd:PRK09111 468 LAEEKRDIKLKAAVERDVRLVRFEPGRLEFALAPGAPRDLAQRLARKLEEWTGRRWVVSVSREGGQPTLAEQEAAAREER 547
                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 567 VIDARQDPDVAAILAHFPGAKIIDVRVRapepeEEGEATPPAAAESEEGDILPGDD 622
Cdd:PRK09111 548 EAAAEADPLVAAVLAAFPGAKIVDVRDL-----APEAAEEEPAAEAEDPDALPDDD 598
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
18-379 3.51e-159

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 460.50  E-value: 3.51e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   18 YRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGE 97
Cdd:TIGR02397   1 YQVLARKYRPQTFED-VIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPC----NECE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:TIGR02397  76 SCKEINSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATT 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:TIGR02397 156 EPHKIPATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDV 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPdaANDPSLSEVERTKAAE 337
Cdd:TIGR02397 236 NELLGLVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTP--SNLLAVLESEQEFLKE 313
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 517259200  338 FAKGVAVTTLSRIWQMLLKGIPETEGS--SRTagAAEMVLIRLA 379
Cdd:TIGR02397 314 LALKLSLEFLLRLLDILLEALKDLRFSndPRI--WLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
27-380 1.18e-155

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 450.80  E-value: 1.18e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  27 PKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPtidlrtPGE--HCQAIME 104
Cdd:COG2812    6 PQTFDDV-VGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEP------CGEceSCRAIAA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 105 GRHVDVIEMDA-ASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVP 183
Cdd:COG2812   79 GSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 184 ITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAgvvqaeavrgmlgL 263
Cdd:COG2812  159 PTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFGL-------------L 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 264 ADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAanDPSLSEVERTKAAEFAKGVA 343
Cdd:COG2812  226 DRRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDA--ELLVNEDERERLQELARRLS 303
                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 517259200 344 VTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAH 380
Cdd:COG2812  304 PERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
17-390 3.78e-130

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 393.85  E-value: 3.78e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  17 GYRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTpg 96
Cdd:PRK05563   2 MYQALYRKWRPQTFED-VVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEI-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 ehCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFAT 176
Cdd:PRK05563  79 --CKAITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILAT 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 177 TEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEA 256
Cdd:PRK05563 157 TEPHKIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYED 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 257 VRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAAnDPSLSEVERTKAA 336
Cdd:PRK05563 237 ALEVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELE-ILDESTENDELFK 315
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 517259200 337 EFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDA 390
Cdd:PRK05563 316 ELSEKLDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASPEYDT 369
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
21-394 1.04e-127

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 385.29  E-value: 1.04e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYktseIDKPTIDLRTPGEHCQ 100
Cdd:PRK14964   3 LALKYRPSSFKDL-VGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNC----SNGPTSDPCGTCHNCI 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 AIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR 180
Cdd:PRK14964  78 SIKNSNHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVK 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 181 KVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRGM 260
Cdd:PRK14964 158 KIPVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 261 LGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAgANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSEVERTKAaefAK 340
Cdd:PRK14964 238 LGCVDKHILEDLVEAILLGDAQSALNVFRELCNT-SNPVIILEGMLQIIYEICYFSITKEIDFLLGEDLITRIKS---LK 313
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 517259200 341 GVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRL 394
Cdd:PRK14964 314 IGSTIFLSRLWQMLLKGIQEVKSSTCVKQAAEMMIIRLCYLSDLPSPQQIIKKI 367
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
18-586 8.54e-122

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 372.92  E-value: 8.54e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSeidkPTIDLRTPGE 97
Cdd:PRK14965   3 YLVLARKYRPQTFSD-LTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQG----LTAEPCNVCP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK14965  78 PCVEITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK14965 158 EPHKVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDV 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSEVERTKAAE 337
Cdd:PRK14965 238 AELLGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAVGEPGDLLDLSEAELAELRA 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 338 FAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAA----------HLPAPEDAARRLAEFSGDNSGPRPA 407
Cdd:PRK14965 318 QAAAADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMATLApgapvselldRLEALERGAPAPPSAAWGAPTPAAP 397
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 408 APPSGNGGGNGTRVSYQNSVAARAAEtapsppqpsapvAMLRAVPSSQPETMSVGRIEPKPAEALKPLVPVnsvndivnl 487
Cdd:PRK14965 398 AAPPPAAAPPVPPAAPARPAAARPAP------------APAPPAAAAPPARSADPAAAASAGDRWRAFVAF--------- 456
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 488 aTEKRDPKLKAMVRtFLRPVRIEAGRLDVSLAPGAP-------TTLLNELAVKLKEWTG---IHWIVSLSRDEGQ--PTL 555
Cdd:PRK14965 457 -VKGKKPALGASLE-QGSPLGVSAGLLEIGFPEGSFelsamqdPDSRAELKALAEQFFGrptRLRITVLAAPPGAapPSL 534
                        570       580       590
                 ....*....|....*....|....*....|....*
gi 517259200 556 VE---AEARTREQHVID-ARQDPDVAAILAHFPGA 586
Cdd:PRK14965 535 AEkkaAEREQRQARLREeAREHPLVQEALRVFGGE 569
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
18-494 3.85e-117

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 363.03  E-value: 3.85e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrtpGE 97
Cdd:PRK07994   3 YQVLARKWRPQTFAE-VVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPC------GE 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 --HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFA 175
Cdd:PRK07994  76 cdNCREIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 176 TTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAE 255
Cdd:PRK07994 156 TTDPQKLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTD 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 256 AVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSEVERtkA 335
Cdd:PRK07994 236 DVSAMLGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELR--L 313
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 336 AEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIR-LAHAAHLPAPEDAARRlAEFSGDNSGPRPAAPPSGNG 414
Cdd:PRK07994 314 RELARTLPPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRmLAFHPAAPLPEPEVPP-QSAAPAASAQATAAPTAAVA 392
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 415 GGNGTRVSyQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAE-------ALKPLVPVNSVNDIVNL 487
Cdd:PRK07994 393 PPQAPAVP-PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASrarpvnsALERLASVRPAPSALEK 471

                 ....*..
gi 517259200 488 ATEKRDP 494
Cdd:PRK07994 472 APAKKEA 478
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
20-294 2.07e-114

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 352.41  E-value: 2.07e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  20 VLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGEHC 99
Cdd:PRK08451   3 ALALKYRPKHFDEL-IGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPC----DTCIQC 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 QAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEI 179
Cdd:PRK08451  78 QSALENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDP 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 180 RKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRG 259
Cdd:PRK08451 158 LKLPATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVAD 237
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 517259200 260 MLGLADRARIVDLFQHIVKGDVAAALG---EFQNqYEA 294
Cdd:PRK08451 238 MLGLLDPSKLEDFFQAILNQDKEKLFEllkELED-YEA 274
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
16-411 5.33e-114

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 350.97  E-value: 5.33e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  16 TGYRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrtp 95
Cdd:PRK14969   1 MSYQVLARKWRPKSFSEL-VGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPC------ 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  96 G--EHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFI 173
Cdd:PRK14969  74 GvcSACLEIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFI 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 174 FATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQ 253
Cdd:PRK14969 154 LATTDPQKIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVN 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 254 AEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDpslSEVERT 333
Cdd:PRK14969 234 ESEVRAMLGAIDQDYLFALLEALLAQDGAALLAIADAMEERSLSFDAALQDLAALLHRLAIAQTVPDSIAD---DLPERD 310
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517259200 334 KAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIR-LAHAAHLPAPEDAARRLAEFSGDNSGPRPAAPPS 411
Cdd:PRK14969 311 RLLDLAKRLSPEDIQLYYQIALHGRRDLGLAPDEYAGFTMTLLRmLAFRPSEQDSGAGRAPGAVPGVNRTRAVPTAAPA 389
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
19-591 2.32e-111

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 346.03  E-value: 2.32e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  19 RVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEidkPTIDLRTPGEH 98
Cdd:PRK14950   4 QVLYRKWRSQTFAEL-VGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTND---PKGRPCGTCEM 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  99 CQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTE 178
Cdd:PRK14950  80 CRAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTE 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 179 IRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVR 258
Cdd:PRK14950 160 VHKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQ 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 259 GMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGAnpvvvltDLADFTH-LVTRLKYVP--DAANDPSLSEVERTKA 335
Cdd:PRK14950 240 SLLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGA-------DLRQFTRdLVEYLRQVMllNSGADRSLLDLTADEK 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 336 AEFAKGVAVTTLSRIWQMlLKGIPETEGSSRTAG----AAEMVLIRlAHAAHLPAPEDAARRLAEFSGDNSGPRPAAPPS 411
Cdd:PRK14950 313 AALQKVSQIANLEALTKW-VKAFSQLDFQLRTTSygqlPLELAVIE-ALLVPVPAPQPAKPTAAAPSPVRPTPAPSTRPK 390
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 412 GNGGGNGTRVSYQNSVAARaaETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAEALKPLVPVNSVNDIVNLA--- 488
Cdd:PRK14950 391 AAAAANIPPKEPVRETATP--PPVPPRPVAPPVPHTPESAPKLTRAAIPVDEKPKYTPPAPPKEEEKALIADGDVLEqle 468
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 489 ---------TEKRDPKLKAMVRTFLRPVRIEAGRLDVSLAPGAPTTLLNELAVK------LKEWTGIHWIVSLSRDEGQP 553
Cdd:PRK14950 469 aiwkqilrdVPPRSPAVQALLSSGVRPVSVEKNTLTLSFKSKFHKDKIEEPENRkiteelLSNFVGKTCAVRCTIEEKSE 548
                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 517259200 554 TLVEAEARTREqhvidARQDPDVAAILAHFpGAKIIDV 591
Cdd:PRK14950 549 EPGDLREQIRE-----ARKDHLVKAAQNIF-DAQIISV 580
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
18-390 1.47e-105

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 328.36  E-value: 1.47e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTPGE 97
Cdd:PRK06645   8 YIPFARKYRPSNFAEL-QGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENTTIKTCEQCT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK06645  87 NCISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAI---AHGAGVVQA 254
Cdd:PRK06645 167 EVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAAsmsAKSDNIISP 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 255 EAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSEVERTK 334
Cdd:PRK06645 247 QVINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFIAYLNKVKMLPNYSLPIYESFNDRTK 326
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 335 AaeFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDA 390
Cdd:PRK06645 327 S--ILDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIKSIYSTSLPLLTDF 380
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
18-358 3.92e-105

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 330.77  E-value: 3.92e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSeiDKPTIdlrTP-G 96
Cdd:PRK14948   3 YEPLHHKYRPQRFDEL-VGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNS--DKPTP---EPcG 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 --EHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIF 174
Cdd:PRK14948  77 kcELCRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVL 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 175 ATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQaIAHGAGVVQA 254
Cdd:PRK14948 157 ATTDPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITP 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 255 EAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTH-LVtrlkyVPDAANDPS----LSE 329
Cdd:PRK14948 236 EAVWDLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFYRdLL-----LAKTAPNRPdlvaVSQ 310
                        330       340
                 ....*....|....*....|....*....
gi 517259200 330 VERTKAAEFAKGVAVTTLSRiWQMLLKGI 358
Cdd:PRK14948 311 QTWDELCKLAKQINLERILQ-WQQHLKGS 338
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
18-525 4.60e-105

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 330.91  E-value: 4.60e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYK--------TSeidkpt 89
Cdd:PRK14951   3 YLVLARKYRPRSFSE-MVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQgpdgqggiTA------ 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  90 idlrTPGEHCQA---IMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEP 166
Cdd:PRK14951  76 ----TPCGVCQAcrdIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEP 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 167 PEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIA 246
Cdd:PRK14951 152 PEYLKFVLATTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIA 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 247 HGAGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPS 326
Cdd:PRK14951 232 FGSGQLQEAAVRQMLGSVDRSHVFRLIDALAQGDGRTVVETADELRLNGLSAASTLEEMAAVLQRMAVLQAVPQAAAAAT 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 327 LSEvertkAAEFAKGVAV-----TTLsrIWQMLLKGIPETEGSSRTAGAAEMVLIRLahAAHLPApedaarrlaeFSGDN 401
Cdd:PRK14951 312 DPE-----AAEVARLAALmpadeTQL--LYSICLHGRAELGLAPDEYAALTMVLLRL--LAFKPA----------AAAEA 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 402 SGPRPAAPPsgngggngTRVSYQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAEALKPLVPVNSV 481
Cdd:PRK14951 373 AAPAEKKTP--------ARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA 444
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*
gi 517259200 482 NDIVNLATEKRDPKLKAM-VRTFLRPVRIEAGRLDVSLAPGAPTT 525
Cdd:PRK14951 445 VALAPAPPAQAAPETVAIpVRVAPEPAVASAAPAPAAAPAAARLT 489
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
18-474 3.62e-104

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 330.86  E-value: 3.62e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTpge 97
Cdd:PRK14960   2 YQVLARKYRPRNFNEL-VGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCAT--- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 hCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK14960  78 -CKAVNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATT 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK14960 157 DPQKLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDV 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGD---VAAALGEFQNQyeaGANPVVVLTDLADFTHLVTRLKYVPDAAndPSLSEVERTK 334
Cdd:PRK14960 237 KEMLGLIDRTIIYDLILAVHQNQrekVSQLLLQFRYQ---ALDVSLVLDQLISTLHELALLQYLPELG--LKYSEEINAK 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 335 AAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLahAAHLP-APEDAArrLAEFSGDNSGPRPAAPPSGN 413
Cdd:PRK14960 312 ILQLSKLISAQDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRL--LAFRPlAPNEIL--VSEPVQQNGQAEVGLNSQAQ 387
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517259200 414 GGGNGTRVSYQNSVAARAAEtapsppqpsapvAMLRAVPSSQPETMSVGRIEPKPAEALKP 474
Cdd:PRK14960 388 TAQEITPVSAVQPVEVISQP------------AMVEPEPEPEPEPEPEPEPEPEPEPEPEP 436
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
18-494 7.11e-102

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 325.12  E-value: 7.11e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLrtpgE 97
Cdd:PRK08691   3 YQVLARKWRPKTFADL-VGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVC----Q 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK08691  78 SCTQIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK08691 158 DPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDV 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPD--AANDPslsevERTKA 335
Cdd:PRK08691 238 RQMIGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGELAILLQQLALIQAVPSalAHDDP-----DSDIL 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 336 AEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLAEFSGDNSgprpaaPPSGNGG 415
Cdd:PRK08691 313 HRLAQTISGEQIQLYYQIAVHGKRDLSLAPDEYAGFMMTLLRMLAFAPLAAASCDANAVIENTELQS------PSAQTAE 386
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 416 GNGTRVSYQNSVAARAAETAPSPPQPSAPVAMLRAV-PSSQPETMSVGRIEPKPAEALKPLVPVNSVNDIVNLATEKRDP 494
Cdd:PRK08691 387 KETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAgPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETP 466
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
16-308 8.82e-96

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 301.31  E-value: 8.82e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  16 TGYRVLARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKtseidKPTIDlRTP 95
Cdd:PRK06305   2 TSYQVSSRKYRPQTFSE-ILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQ-----NPTED-QEP 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  96 GEHC---QAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKF 172
Cdd:PRK06305  75 CNQCascKEISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 173 IFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVV 252
Cdd:PRK06305 155 FLATTEIHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSL 234
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 253 QAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADF 308
Cdd:PRK06305 235 DPDSVAKALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLF 290
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
18-285 2.75e-95

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 301.36  E-value: 2.75e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGE 97
Cdd:PRK14953   3 YIPFARKYRPKFFKEV-IGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPC----GKCE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK14953  78 NCVEIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK14953 158 EYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVV 237
                        250       260
                 ....*....|....*....|....*...
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAAL 285
Cdd:PRK14953 238 EEFLGIVSQESVRKFLNLLLESDVDEAI 265
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
18-305 2.59e-94

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 305.59  E-value: 2.59e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEidkptiDLRTPGE 97
Cdd:PRK07133   5 YKALYRKYRPKTFDDI-VGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHKT------DLLEPCQ 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEgRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK07133  78 ECIENVN-NSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATT 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK07133 157 EVHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNV 236
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDL 305
Cdd:PRK07133 237 EELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISL 284
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
18-621 1.94e-92

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 299.87  E-value: 1.94e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNykTSEIDKPTIDLRTPGE 97
Cdd:PRK12323   3 YQVLARKWRPRDFTTL-VGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLN--CTGADGEGGITAQPCG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIME---GRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIF 174
Cdd:PRK12323  80 QCRACTEidaGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFIL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 175 ATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQA 254
Cdd:PRK12323 160 ATTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSE 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 255 EAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDA--ANDPSLSEVER 332
Cdd:PRK12323 240 EAVRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRSLSFAGALQDLASLLQKIALAQVVPAAvqDDWPEADDIRR 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 333 TKAAEFAKGVAVttlsrIWQMLLKGIPETEGSSRTAGAAEMVLIRLAhaahlpapedaARRLAEFSGDNSGPRPAAPPsg 412
Cdd:PRK12323 320 LAGRFDAQEVQL-----FYQIANLGRSELALAPDEYAGFTMTLLRML-----------AFRPGQSGGGAGPATAAAAP-- 381
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 413 ngGGNGTRVSYQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAEALKPLVPVNSVNDIVNLATEKR 492
Cdd:PRK12323 382 --VAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPA 459
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 493 DPKLKAMVRtfLRPVRIEAGRLDVSLAPGAPTTLLNELAVKLKEWTGIHWIVSLSRDEGQPTLVEAEARTREQhvidARQ 572
Cdd:PRK12323 460 AAARPAAAG--PRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPA----TAD 533
                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*....
gi 517259200 573 DPDVAAILAHFPGAKIidVRVRAPEPEEEGEATPPAAAESEEGDILPGD 621
Cdd:PRK12323 534 PDDAFETLAPAPAAAP--APRAAAATEPVVAPRPPRASASGLPDMFDGD 580
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
18-474 1.48e-91

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 295.15  E-value: 1.48e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFtDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTseidkPTIDLRTPG- 96
Cdd:PRK14971   4 YIVSARKYRPSTF-ESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQN-----LTADGEACNe 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 -EHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFA 175
Cdd:PRK14971  78 cESCVAFNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILA 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 176 TTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAE 255
Cdd:PRK14971 158 TTEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYK 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 256 AVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTH--LVTRlkyvpDAANDPSL--SEVE 331
Cdd:PRK14971 238 SVIENLNILDYDYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGLASHFRdlLVCK-----DAATLQLLevGESI 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 332 RTKAAEFAKGVAVttlsriwQMLLKGIPETEGSSRTAGAA-------EMVLIRLAH-----AAHLPAPEDAARRLAEFSG 399
Cdd:PRK14971 313 RQRYLEQAQKCPM-------SFLYRALKLCNQCDLNYRASknkrllvELTLIQLAQltqkgDDASGGRGPKQHIKPVFTQ 385
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517259200 400 DNSGPRPAAPPSGNGGGNGTRVSYQNSVAARAaeTAPSPPQPSAPVAMLRAVPSSQPETMSvGRIEPKPAEALKP 474
Cdd:PRK14971 386 PAAAPQPSAAAAASPSPSQSSAAAQPSAPQSA--TQPAGTPPTVSVDPPAAVPVNPPSTAP-QAVRPAQFKEEKK 457
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
18-332 3.02e-91

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 292.83  E-value: 3.02e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSeidkPTIdlrTP-G 96
Cdd:PRK06647   3 YRGTATKRRPRDFNSL-EGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNG----PTP---MPcG 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 E--HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIF 174
Cdd:PRK06647  75 EcsSCKSIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 175 ATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQA 254
Cdd:PRK06647 155 ATTEVHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITL 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 255 EAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADF-------THLVTRLKYVPDAANDP-- 325
Cdd:PRK06647 235 EQIRSKMGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFfrellflKHGIKNEAFIGIKAERLpe 314
                        330
                 ....*....|..
gi 517259200 326 -----SLSEVER 332
Cdd:PRK06647 315 klrefDLSQIER 326
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
18-377 1.28e-90

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 284.78  E-value: 1.28e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGE 97
Cdd:PRK14961   3 YQILARKWRPQYFRDI-IGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPC----RKCI 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK14961  78 ICKEIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK14961 158 DVEKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNV 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDaANDPSLSEVERTKAAE 337
Cdd:PRK14961 238 TDMLGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQSFPK-IWNTIFIKNYKNQIQK 316
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 517259200 338 FAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIR 377
Cdd:PRK14961 317 IAQNNKKTNIQLCYQILLNGRKELKFAPDQKIGVEMTLLR 356
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
18-357 4.63e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 293.55  E-value: 4.63e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFtDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrtpGE 97
Cdd:PRK14949   3 YQVLARKWRPATF-EQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPC------GV 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 --HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFA 175
Cdd:PRK14949  76 csSCVEIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 176 TTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAE 255
Cdd:PRK14949 156 TTDPQKLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLT 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 256 AVRGMLGLADRARIVDLFQHIVKGDVAAALgefqnQYEA-----GANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSev 330
Cdd:PRK14949 236 QVQTMLGSIDEQHVIALLKALTDADIGVLM-----QTCAqvlafGADAQEVLRSLLELLHQITLTQFAPAAAQQSLYS-- 308
                        330       340
                 ....*....|....*....|....*..
gi 517259200 331 ERTKAaeFAKGVAVTTLSRIWQMLLKG 357
Cdd:PRK14949 309 EQIRA--FAEQLSPEQVQLYYQILLTG 333
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
18-474 1.13e-85

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 285.20  E-value: 1.13e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTpge 97
Cdd:PRK07003   3 YQVLARKWRPKDFASL-VGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRA--- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 hCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK07003  79 -CREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK07003 158 DPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAV 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAAND--PSLSEVERTKA 335
Cdd:PRK07003 238 SGMLGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLLHRIAWAQFAPASVLDewPEAADLRRFAE 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 336 AEFAKGV----AVTTLSR------------IWQMLLKGI---PETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLAE 396
Cdd:PRK07003 318 LLSPEQVqlfyQIATVGRgelglapdeyagFTMTLLRMLafePAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVP 397
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517259200 397 FSGDNSGPRPAAP-PSGNGGGNGTRVSYQNSVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMSVGRIEPKPAEALKP 474
Cdd:PRK07003 398 AVTAVTGAAGAALaPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGS 476
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
20-338 5.36e-85

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 277.88  E-value: 5.36e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  20 VLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYktseIDKPTIDLRTPGEHC 99
Cdd:PRK05896   5 TFYRKYRPHNFKQI-IGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINC----LNPKDGDCCNSCSVC 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 QAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEI 179
Cdd:PRK05896  80 ESINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEF 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 180 RKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRG 259
Cdd:PRK05896 160 QKIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINK 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 260 MLGLADRARIVDLFQHIVKGDVAAALgEFQNQYEA-GANPVVVLTDLadFTHLVTRLKY--VPDAANDPSLSEvERTKAA 336
Cdd:PRK05896 240 TFGLVDNNKKINLIELIQKNDIEELR-NLINELESkGINFEAFCRDL--INLLIDLLVYqkTKNINLLKKLSK-EQLKTL 315

                 ..
gi 517259200 337 EF 338
Cdd:PRK05896 316 NL 317
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
20-305 8.43e-85

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 273.18  E-value: 8.43e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  20 VLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTpgehC 99
Cdd:PRK14962   3 ALYRKYRPKTFSEV-VGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRA----C 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 QAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEI 179
Cdd:PRK14962  78 RSIDEGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 180 RKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRG 259
Cdd:PRK14962 158 EKVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHE 237
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 517259200 260 MLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDL 305
Cdd:PRK14962 238 ALGLIPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQA 283
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
18-324 2.74e-84

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 274.27  E-value: 2.74e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGE 97
Cdd:PRK14957   3 YQALARKYRPQSFAEV-AGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPC----NKCE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PRK14957  78 NCVAINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAV 257
Cdd:PRK14957 158 DYHKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQI 237
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLAD--FTHLVTRLKYVPDAAND 324
Cdd:PRK14957 238 KQMLGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEiwFACCIYSFTQSLDAVND 306
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
21-519 1.13e-80

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 263.62  E-value: 1.13e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFtDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYkTSEIDKPTIDLrtpgEHCQ 100
Cdd:PRK14963   4 LYQRARPITF-DEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGEC----ESCL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 AIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR 180
Cdd:PRK14963  78 AVRRGAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPE 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 181 KVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEaVRGM 260
Cdd:PRK14963 158 KMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALGTPVTRKQ-VEEA 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 261 LGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLadfthlvtrlkyvpdaandpslseVERTKAAEFAK 340
Cdd:PRK14963 237 LGLPPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGL------------------------LEAFRAALYAE 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 341 gvavttlsriwqMLLKGIPETEGSSRTAGAAEMVL----IRLAHAAHLPAPEDA---ARRLAEFSGDNSGPRPAAPPSGN 413
Cdd:PRK14963 293 ------------LGLGGGPRLEGAEPRLLAAMTALdeqmERFARRSDALSLELAllhALLALGGAPSEGVAAVAPPAPAP 360
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 414 GGGNGTRVSYQNSVA-ARAAETapsppqpsapvAMLRAVPSSQPETMSVGRIEPKP--AEALKPLVPVNSVNDIVNLATE 490
Cdd:PRK14963 361 ADLTQRLNRLEKEVRsLRSAPT-----------AAATAAGAPLPDFDPRPRGPPAPepARSAEAPPLVAPAAAPAGLALR 429
                        490       500       510
                 ....*....|....*....|....*....|.
gi 517259200 491 KRD--PKLKAMVRTFLRPVRIEAGRLDVSLA 519
Cdd:PRK14963 430 WRDvlAALKMQLRAFLREARPHVEEGYVSLT 460
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
18-285 4.74e-78

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 253.28  E-value: 4.74e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTPG- 96
Cdd:PRK14955   3 YQVIARKYRPKKFADI-TAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDADYLQEVTEPc 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 ---EHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFI 173
Cdd:PRK14955  82 gecESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFI 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 174 FATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIA-----HG 248
Cdd:PRK14955 162 FATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAfsvesEG 241
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 517259200 249 AGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAAL 285
Cdd:PRK14955 242 EGSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAML 278
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
21-404 1.08e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 258.84  E-value: 1.08e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrTPGEHCQ 100
Cdd:PRK14959   6 LTARYRPQTFAEV-AGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPC----NTCEQCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 AIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR 180
Cdd:PRK14959  81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 181 KVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRGM 260
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 261 LGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANdPSLS--EVERTKAAEF 338
Cdd:PRK14959 241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLRQAGEAAL-ASLDlpEDEARQWLGW 319
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 339 AKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARrlaefSGDNSGP 404
Cdd:PRK14959 320 AKRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLNLAMLPRLMPVESLRP-----SGGGASA 380
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
14-325 2.68e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 254.10  E-value: 2.68e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  14 TGTgYRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLR 93
Cdd:PRK14956   2 SGT-HEVLSRKYRPQFFRDV-IHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECT 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  94 TpgehCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFI 173
Cdd:PRK14956  80 S----CLEITKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFI 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 174 FATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQ 253
Cdd:PRK14956 156 LATTEFHKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLT 235
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517259200 254 AEAVRGMLGLADRARIVDLFQHIVKGDVAAALGE-FQNQYEAGANPVVVLTDLADFTHlvtRLKYVPDAANDP 325
Cdd:PRK14956 236 GVKIRKMIGYHGIEFLTSFIKSLIDPDNHSKSLEiLESLYQEGQDIYKFLWDSIEFTH---TLNLIRDSLADR 305
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
18-285 4.49e-76

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 254.48  E-value: 4.49e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  18 YRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSeIDKPTI--DLRTP 95
Cdd:PRK14954   3 YQVIARKYRPSKFADI-TAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRM-IDDPVYlqEVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  96 GEHCQAIME---GRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKF 172
Cdd:PRK14954  81 CGECESCRDfdaGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 173 IFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAG-- 250
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSVGse 240
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 517259200 251 ---VVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAAL 285
Cdd:PRK14954 241 aekVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKML 278
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
17-378 4.30e-74

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 246.18  E-value: 4.30e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  17 GYRVLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLrtpg 96
Cdd:PRK14958   2 AHQVLARKWRPRCFQEV-IGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDC---- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 EHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFAT 176
Cdd:PRK14958  77 ENCREIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILAT 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 177 TEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEA 256
Cdd:PRK14958 157 TDHHKLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIAD 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 257 VRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAandpsLSEVERTKAA 336
Cdd:PRK14958 237 VKTMLGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVPEA-----LIENDSEQLR 311
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 517259200 337 EFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRL 378
Cdd:PRK14958 312 QLAKLLDREDVQLFYQIGLIGQRDLAYSPTPQTGFEMTLLRM 353
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
20-288 9.88e-74

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 240.93  E-value: 9.88e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  20 VLARKYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNykTSEIDKPTidlrtpgehc 99
Cdd:PRK14970   6 VSARKYRPQTFDDV-VGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKIN--QPGYDDPN---------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 qaimEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEI 179
Cdd:PRK14970  73 ----EDFSFNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEK 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 180 RKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRG 259
Cdd:PRK14970 149 HKIIPTILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTE 228
                        250       260
                 ....*....|....*....|....*....
gi 517259200 260 MLGLADRARIVDLFQHIVKGDVAAALGEF 288
Cdd:PRK14970 229 NLNILDYDTYINVTDLILENKIPELLLAF 257
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
21-394 4.78e-73

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 245.56  E-value: 4.78e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYktseIDKPTidlRTPGEHCQ 100
Cdd:PRK14952   3 LYRKYRPATFAE-VVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNC----AQGPT---ATPCGVCE 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 AIME-GR----HVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFA 175
Cdd:PRK14952  75 SCVAlAPngpgSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFA 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 176 TTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGV-VQA 254
Cdd:PRK14952 155 TTEPEKVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAADThVTY 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 255 EAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAAN----DPSLSEV 330
Cdd:PRK14952 235 QRALGLLGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQAVPDAAArgvvDAPEDVL 314
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517259200 331 ERTKaaEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAhaahLPAPEDAARRL 394
Cdd:PRK14952 315 ERMR--EQAARIGLATLTRYAEVVQAGLGEMRGATAPRLLLEVVCARLL----LPSASDAESAL 372
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
21-471 3.55e-63

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 223.71  E-value: 3.55e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPT------IDLRT 94
Cdd:PRK07764   5 LYRRYRPATFAE-VIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCgecdscVALAP 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  95 --PGEhcqaimegrhVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKF 172
Cdd:PRK07764  84 ggPGS----------LDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKF 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 173 IFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAhGAG-- 250
Cdd:PRK07764 154 IFATTEPDKVIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLA-GAGpe 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 251 VVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLAD-FTHLVTrLKYVPDAAN----DP 325
Cdd:PRK07764 233 GVTYERAVALLGVTDSALIDEAVDALAAGDGAALFGTVDRVIEAGHDPRRFAEDLLErLRDLIV-LQAVPDAAErglvDA 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 326 SLSEVERTKAAEFAKGVAvtTLSRIW-------------------------QMLLKGIPETEGSsrTAGAAEMVLIRLAH 380
Cdd:PRK07764 312 PADQLDRMRAQAQRLGPA--ELTRAAdvvndgltemrgatsprlllellcaRMLLPSASDDERG--LLARLERLERRLGV 387
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 381 AAHLPAPEDAARRLAEfsgdnSGPRPAAPPSGNGGGNGTRVSYQnsVAARAAETAPSPPQPSAPVAMLRAVPSSQPETMS 460
Cdd:PRK07764 388 AGGAGAPAAAAPSAAA-----AAPAAAPAPAAAAPAAAAAPAPA--AAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAA 460
                        490
                 ....*....|.
gi 517259200 461 VGRIEPKPAEA 471
Cdd:PRK07764 461 APSAQPAPAPA 471
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
252-394 7.74e-58

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 190.94  E-value: 7.74e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  252 VQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDAANDPSLSEVE 331
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPDAADDLLLPEEE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517259200  332 RTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRL 394
Cdd:pfam12169  81 RARLAELAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLRLAYAASLPPPEELLRRL 143
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
37-293 3.66e-47

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 167.46  E-value: 3.66e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  37 QEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDlrtpgEHCQAIMEGRHVDVIEM--D 114
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQ-----CHSRLMAAGNHPDLLELnpE 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 115 AASHT-GIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRF 193
Cdd:COG0470   76 EKSDQiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVI 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 194 DLRRISASDLVglftTIAAKEGIeaEADALAMIARAAEGSARDGLSLLdQAIAHGAGVVQAeavrgMLGLADRARIVDLF 273
Cdd:COG0470  156 RFRPPSEEEAL----AWLREEGV--DEDALEAILRLAGGDPRAAINLL-QALAGRKELLED-----LAALLSRDRALELL 223
                        250       260
                 ....*....|....*....|
gi 517259200 274 QHIVKGDVAAALGEFQNQYE 293
Cdd:COG0470  224 DALLKAEALELLDWLLKWLL 243
DUF3646 pfam12362
DNA polymerase III gamma and tau subunits C terminal; This domain family is found in bacteria, ...
478-591 3.41e-43

DNA polymerase III gamma and tau subunits C terminal; This domain family is found in bacteria, and is approximately 120 amino acids in length. The family is found in association with pfam00004. The proteins in this family are frequently annotated as the gamma and tau subunits of DNA polymerase III, however there is little accompanying literature to back this up.


Pssm-ID: 432506 [Multi-domain]  Cd Length: 114  Bit Score: 150.41  E-value: 3.41e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  478 VNSVNDIVNLATEKRDPKLKAMVRTFLRPVRIEAGRLDVSLAPGAPTTLLNELAVKLKEWTGIHWIVSLSRDEGQPTLVE 557
Cdd:pfam12362   1 LPSFEDLVALAEEKRDIKLKAELERYVRLVRFEPGRLEFALAPGAPRDLAQRLARKLKEWTGRRWTVSLSSEPGEPTLAE 80
                          90       100       110
                  ....*....|....*....|....*....|....
gi 517259200  558 AEARTREQHVIDARQDPDVAAILAHFPGAKIIDV 591
Cdd:pfam12362  81 QEAAAKAARRAAARAHPLVAAVLAAFPGAEIVDV 114
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
36-199 3.88e-41

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 146.59  E-value: 3.88e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   36 GQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTpgehCQAIMEGRHVDV--IEM 113
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRS----CRRIESGNHPDLviIEP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  114 DAASHtGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRF 193
Cdd:pfam13177  77 EGQSI-KIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQII 155

                  ....*.
gi 517259200  194 DLRRIS 199
Cdd:pfam13177 156 RFKPLS 161
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
42-235 1.00e-39

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 143.92  E-value: 1.00e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   42 RTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPtiDLRTPGehCQAIMEGRHVDV--IEMDAASHt 119
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEP--CGECHS--CRLIEAGNHPDLhrLEPEGQSI- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  120 GIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRIS 199
Cdd:TIGR00678  77 KVDQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLS 156
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 517259200  200 ASDLVglftTIAAKEGIEAEADALAmiARAAEGSAR 235
Cdd:TIGR00678 157 EEALL----QWLIRQGISEEAAELL--LALAGGSPG 186
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
24-320 5.18e-23

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 100.45  E-value: 5.18e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  24 KYRPKDFtDLMVGQEPMVRTLTNAFETGrIAQAYMLTGVRGVGKTTTARILARAL---NYKTSEIDKPTIDLRTPGeHCQ 100
Cdd:PRK12402   8 KYRPALL-EDILGQDEVVERLSRAVDSP-NLPHLLVQGPPGSGKTAAVRALARELygdPWENNFTEFNVADFFDQG-KKY 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 AIMEGRHVDVIEMDAASHTG-IDDIREII-EQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTE 178
Cdd:PRK12402  85 LVEDPRFAHFLGTDKRIRSSkIDNFKHVLkEYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATRQ 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 179 IRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLdQAIAHGAGVVQAEAVR 258
Cdd:PRK12402 165 PSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTL-QTAALAAGEITMEAAY 243
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517259200 259 GMLGLADR-ARIVDLFQHIVKGDVAAALGEFQN-QYEAGANPVVVLTDLadftHLVTRLKYVPD 320
Cdd:PRK12402 244 EALGDVGTdEVIESLLDAAEAGDFTDARKTLDDlLIDEGLSGGEVLEEL----LRVARSRYRGD 303
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
21-246 7.54e-23

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 101.31  E-value: 7.54e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFTDlMVGQEPMV---RTLTNAFETGRIAQAyMLTGVRGVGKTTTARILARALNYKtseidkptidlrtpge 97
Cdd:PRK13342   2 LAERMRPKTLDE-VVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATDAP---------------- 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 hcqaimegrhvdVIEMDAAShTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLST--QAFngLLKTLEEppEHVKFIFA 175
Cdd:PRK13342  64 ------------FEALSAVT-SGVKDLREVIEEARQRRSAGRRTILFIDEIHRFNKaqQDA--LLPHVED--GTITLIGA 126
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517259200 176 TTE-----IRKvPItvLSRCQRFDLRRISASDLVGLFTTIAAKEG---IEAEADALAMIARAAEGSARDGLSLLDQAIA 246
Cdd:PRK13342 127 TTEnpsfeVNP-AL--LSRAQVFELKPLSEEDIEQLLKRALEDKErglVELDDEALDALARLANGDARRALNLLELAAL 202
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
41-285 9.93e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 99.61  E-value: 9.93e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  41 VRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRtpgeHCQAIMEGRHVDV--IEMDAASh 118
Cdd:PRK08058  15 VKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCT----NCKRIDSGNHPDVhlVAPDGQS- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 119 TGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRI 198
Cdd:PRK08058  90 IKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 199 SASDLVGLFTtiaaKEGIeaeADALAMIARAAEGSARDGLSLL-DQAIAhgagvvQAeavrgmlgladRARIVDLFQHIV 277
Cdd:PRK08058 170 PPESLIQRLQ----EEGI---SESLATLLAGLTNSVEEALALSeDDWFA------QA-----------RALVIKLYEALH 225

                 ....*...
gi 517259200 278 KGDVAAAL 285
Cdd:PRK08058 226 EKDLQSFV 233
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
26-288 1.14e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 100.10  E-value: 1.14e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  26 RPKDFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILAR-ALNYKTSEID---KPTIDLRTPGEH--C 99
Cdd:PRK07471  14 HPRETTAL-FGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARfLLATPPPGGDgavPPPTSLAIDPDHpvA 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 QAIMEGRHVD--VIEMDAASHTG-------IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHV 170
Cdd:PRK07471  93 RRIAAGAHGGllTLERSWNEKGKrlrtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARS 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 171 KFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLfttiAAKEGIEAEADALAMIARAAEGSARDGLSLLDQaiahGAG 250
Cdd:PRK07471 173 LFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDA----LAAAGPDLPDDPRAALAALAEGSVGRALRLAGG----DGL 244
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 517259200 251 VVQAEAVRGMLGL--ADRARIVDLFQHIVKGDVAAALGEF 288
Cdd:PRK07471 245 ALYRRLTALLDTLprLDRRALHALADAAAGRDRAARFALF 284
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
198-262 1.40e-22

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 91.41  E-value: 1.40e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517259200 198 ISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHGAGVVQAEAVRGMLG 262
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
rfc PRK00440
replication factor C small subunit; Reviewed
24-284 3.03e-22

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 98.02  E-value: 3.03e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  24 KYRPKDFTDlMVGQEPMVRTLTNAFETGRIAQaYMLTGVRGVGKTTTARILARALnYktseidkptidlrtpGEHCQAIM 103
Cdd:PRK00440  10 KYRPRTLDE-IVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALAREL-Y---------------GEDWRENF 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 104 egrhvdvIEMDAASHTGIDDIREIIEQ-VRYRPV-SARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRK 181
Cdd:PRK00440  72 -------LELNASDERGIDVIRNKIKEfARTAPVgGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSK 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 182 V--PITvlSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLdQAIAHGAGVVQAEAVRG 259
Cdd:PRK00440 145 IidPIQ--SRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYK 221
                        250       260
                 ....*....|....*....|....*
gi 517259200 260 MLGLADRARIVDLFQHIVKGDVAAA 284
Cdd:PRK00440 222 ITGTARPEEIREMIELALNGDFTEA 246
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
34-203 2.38e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 92.02  E-value: 2.38e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  34 MVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTttarILARALNYKTseIDKPTIDlrtpgehcqaimegRHVDVIE- 112
Cdd:PRK05564   6 IIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKS----LLAKEIALKI--LGKSQQR--------------EYVDIIEf 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 113 --MDAAShTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRC 190
Cdd:PRK05564  66 kpINKKS-IGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRC 144
                        170
                 ....*....|...
gi 517259200 191 QRFDLRRISASDL 203
Cdd:PRK05564 145 QIYKLNRLSKEEI 157
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
32-232 3.20e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 93.05  E-value: 3.20e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  32 DLMVGQEPMVRTLTNA---------FETGRIAQAYMLTGVRGVGKTTTARILARALNyktseidkpTIDLRTPG----EH 98
Cdd:PRK07940   5 DDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQ---------CTDPDEPGcgecRA 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  99 CQAIMEGRHVDV--IEMDAAShTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFAT 176
Cdd:PRK07940  76 CRTVLAGTHPDVrvVAPEGLS-IGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCA 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 177 TEIRKVPITVLSRCQRFDLRRISASDLVGLFTtiaAKEGIEAEADALAmiARAAEG 232
Cdd:PRK07940 155 PSPEDVLPTIRSRCRHVALRTPSVEAVAEVLV---RRDGVDPETARRA--ARASQG 205
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
29-233 5.85e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 91.12  E-value: 5.85e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  29 DFTDLmVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALnyKTSEIDKPTIDLRtpgehcqaIMEGRHV 108
Cdd:PRK07399   2 LFANL-IGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL--LSQGSPSKNIRRR--------LEEGNHP 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 109 DV-------------IEMDAASHTG----------IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEE 165
Cdd:PRK07399  71 DLlwveptyqhqgklITASEAEEAGlkrkappqirLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 166 pPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLvglfTTIAAKEGIEAEADAL--AMIARAAeGS 233
Cdd:PRK07399 151 -PGNGTLILIAPSPESLLPTIVSRCQIIPFYRLSDEQL----EQVLKRLGDEEILNINfpELLALAQ-GS 214
PRK04195 PRK04195
replication factor C large subunit; Provisional
24-274 3.47e-19

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 90.75  E-value: 3.47e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  24 KYRPKDFTDLmVGQEPMVRTLT---NAFETGRIAQAYMLTGVRGVGKTTTARILARALNYktseidkptidlrtpgehcq 100
Cdd:PRK04195   7 KYRPKTLSDV-VGNEKAKEQLRewiESWLKGKPKKALLLYGPPGVGKTSLAHALANDYGW-------------------- 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 aimegrhvDVIEMDAAshtgidDIR--EIIEQV-----RYRPVS-ARYKVYIIDEVHMLSTQAFNG----LLKTLEEPpe 168
Cdd:PRK04195  66 --------EVIELNAS------DQRtaDVIERVageaaTSGSLFgARRKLILLDEVDGIHGNEDRGgaraILELIKKA-- 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 169 hvkfifatteirKVPI-------------TVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSAR 235
Cdd:PRK04195 130 ------------KQPIiltandpydpslrELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLR 197
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 517259200 236 DGLSLLdQAIAHGAGVVQAEAVRgmlGLADRARIVDLFQ 274
Cdd:PRK04195 198 SAINDL-QAIAEGYGKLTLEDVK---TLGRRDREESIFD 232
PLN03025 PLN03025
replication factor C subunit; Provisional
24-305 1.36e-17

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 84.01  E-value: 1.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  24 KYRPKDFTDLmVGQEPMVRTLTNAFETGRIAQaYMLTGVRGVGKTTTARILARAL---NYKTSeidkptidlrtpgehcq 100
Cdd:PLN03025   6 KYRPTKLDDI-VGNEDAVSRLQVIARDGNMPN-LILSGPPGTGKTTSILALAHELlgpNYKEA----------------- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 101 aimegrhvdVIEMDAASHTGIDDIREIIEQVRYRPVS---ARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:PLN03025  67 ---------VLELNASDDRGIDVVRNKIKMFAQKKVTlppGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACN 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EIRKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLdQAIAHGAGVVQAEAV 257
Cdd:PLN03025 138 TSSKIIEPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNL-QATHSGFGFVNQENV 216
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 517259200 258 RGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDL 305
Cdd:PLN03025 217 FKVCDQPHPLHVKNIVRNCLKGKFDDACDGLKQLYDLGYSPTDIITTL 264
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
8-262 3.23e-17

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 84.34  E-value: 3.23e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   8 SKDAASTGTGYRVLARKYRPKDFTDlMVGQEPMV---RTLTNAFETGRIAQayM-LTGVRGVGKTTTARILARALNYKts 83
Cdd:COG2256    2 DDAAAEASAANAPLAERMRPRTLDE-VVGQEHLLgpgKPLRRAIEAGRLSS--MiLWGPPGTGKTTLARLIANATDAE-- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  84 eidkptidlrtpgehcqaimegrhvdVIEMDAAShTGIDDIREIIEQVRYRPVSARYKVYIIDEVHmlstqAFN-----G 158
Cdd:COG2256   77 --------------------------FVALSAVT-SGVKDIREVIEEARERRAYGRRTILFVDEIH-----RFNkaqqdA 124
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 159 LLKTLEEppEHVKFIFATTE-----IRKvPItvLSRCQRFDLRRISASDLVGLFTTIAAKEG-------IEAEADALAMI 226
Cdd:COG2256  125 LLPHVED--GTITLIGATTEnpsfeVNS-AL--LSRCRVFVLKPLSEEDLEQLLERALADDErglggykLELDDEALEAL 199
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 517259200 227 ARAAEGSARDGLSLLDQAIA----HGAGVVQAEAVRGMLG 262
Cdd:COG2256  200 ARLADGDARRALNALELAVLsappDGVIEITLELVEEALQ 239
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
42-202 1.77e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 81.07  E-value: 1.77e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  42 RTLTNAFEtgRIAQAYMLTGVRGVGKTTTARILARALnyktsEIDKPTIDLRTPGE--HCQAIMEGRHVDVIEMDAAS-- 117
Cdd:PRK08699  11 RQIAEHWE--RRPNAWLFAGKKGIGKTAFARFAAQAL-----LCETPAPGHKPCGEcmSCHLFGQGSHPDFYEITPLSde 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 118 --------HTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSR 189
Cdd:PRK08699  84 pengrkllQIKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSR 163
                        170
                 ....*....|...
gi 517259200 190 CQRFDLRRISASD 202
Cdd:PRK08699 164 CRKMVLPAPSHEE 176
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
51-316 1.82e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 77.82  E-value: 1.82e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  51 GRIAQAYMLTGVRGVGKTTTARILARALNyktseIDKPTiDLRTPGE--HCQAIMEGRHVD--VIEMDAASHT-GIDDIR 125
Cdd:PRK05707  19 GRHPHAYLLHGPAGIGKRALAERLAAALL-----CEAPQ-GGGACGSckGCQLLRAGSHPDnfVLEPEEADKTiKVDQVR 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 126 EIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFdlrrisasdlvg 205
Cdd:PRK05707  93 ELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQ------------ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 206 LFTtiaakegIEAEADALAMIARA-AEGSARDGLSLLDQAiahGAGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAa 284
Cdd:PRK05707 161 ACP-------LPSNEESLQWLQQAlPESDERERIELLTLA---GGSPLRALQLHEQGVREQRARVLDGVKKLLKQQQSA- 229
                        250       260       270
                 ....*....|....*....|....*....|...
gi 517259200 285 lgeFQNQYEAGANPVVVLTD-LADFTHLVTRLK 316
Cdd:PRK05707 230 ---SQLAESWLKVPLLLLFDwFCDWAHDILRYQ 259
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
31-248 7.00e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 76.23  E-value: 7.00e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  31 TDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTA-----RILARALNYKTSE----IDKPTIDLR--TPGEHC 99
Cdd:PRK09112  22 NTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAfhlanHILSHPDPAEAPEtladPDPASPVWRqiAQGAHP 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 QAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEI 179
Cdd:PRK09112 102 NLLHITRPFDEKTGKFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSS 181
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517259200 180 RKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEadALAMIARAAEGSARDGLSLldqaIAHG 248
Cdd:PRK09112 182 GRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGSDGE--ITEALLQRSKGSVRKALLL----LNYG 244
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
38-191 1.54e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 68.99  E-value: 1.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  38 EPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEIDKPTidlrtpGE--HCQAIMEGRHVDVIEMDA 115
Cdd:PRK06871   8 QPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPC------GQchSCHLFQAGNHPDFHILEP 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517259200 116 ASHT--GIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQ 191
Cdd:PRK06871  82 IDNKdiGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
123-199 1.57e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 65.51  E-value: 1.57e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517259200 123 DIREIIEQVRYRP-VSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRIS 199
Cdd:PRK07132  73 EFLSAINKLYFSSfVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPD 150
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
118-216 2.55e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 64.82  E-value: 2.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 118 HTgIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRC-----QR 192
Cdd:PRK05917  75 HS-IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSlsihiPM 153
                         90       100
                 ....*....|....*....|....
gi 517259200 193 FDLRRISASDLVGLFTTIAAKEGI 216
Cdd:PRK05917 154 EEKTLVSKEDIAYLIGYAQGKESV 177
PRK04132 PRK04132
replication factor C small subunit; Provisional
106-272 2.81e-11

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 66.79  E-value: 2.81e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 106 RHvDVIEMDAASHTGIDDIREIIEQ-VRYRPV-SARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVP 183
Cdd:PRK04132 596 RH-NFLELNASDERGINVIREKVKEfARTKPIgGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKII 674
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 184 ITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLdQAIAHGAGVVQAEAVrgmLGL 263
Cdd:PRK04132 675 EPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINIL-QAAAALDDKITDENV---FLV 750

                 ....*....
gi 517259200 264 ADRARIVDL 272
Cdd:PRK04132 751 ASRARPEDI 759
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
99-190 5.84e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 64.32  E-value: 5.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  99 CQAIMEGRHVD--VIEMDAASHT-GIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFA 175
Cdd:PRK07993  65 CQLMQAGTHPDyyTLTPEKGKSSlGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLA 144
                         90
                 ....*....|....*
gi 517259200 176 TTEIRKVPITVLSRC 190
Cdd:PRK07993 145 CREPARLLATLRSRC 159
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
35-192 6.59e-11

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 61.01  E-value: 6.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  35 VGQEPMVRTLTNAFEtGRIAQAYMLTGVRGVGKTTTARILARALNYktseidkptidlrtpgehcqaimegRHVDVIEMD 114
Cdd:cd00009    1 VGQEEAIEALREALE-LPPPKNLLLYGPPGTGKTTLARAIANELFR-------------------------PGAPFLYLN 54
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 115 AASHTGIDDIREIIEQVRYR-----PVSARYKVYIIDEVHMLSTQAFNGLLKTLEE------PPEHVKFIFATT--EIRK 181
Cdd:cd00009   55 ASDLLEGLVVAELFGHFLVRllfelAEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNrpLLGD 134
                        170
                 ....*....|.
gi 517259200 182 VPITVLSRCQR 192
Cdd:cd00009  135 LDRALYDRLDI 145
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
47-254 1.67e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 59.59  E-value: 1.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  47 AFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEidkPTIDLRTPgehcQAIMEGRHVDV-----IEMDAA----S 117
Cdd:PRK08769  19 ALDAGRLGHGLLICGPEGLGKRAVALALAEHVLASGPD---PAAAQRTR----QLIAAGTHPDLqlvsfIPNRTGdklrT 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 118 HTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRR 197
Cdd:PRK08769  92 EIVIEQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFKL 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517259200 198 ISASDLVGL-----FTTIAAKEGIEAeadALAMIARAAEGSARDGLSL-------LDQAIAHGAGVVQA 254
Cdd:PRK08769 172 PPAHEALAWllaqgVSERAAQEALDA---ARGHPGLAAQWLREDGLALrravaqdLEQIASGRAGAVDV 237
44 PHA02544
clamp loader, small subunit; Provisional
24-224 2.14e-09

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 59.23  E-value: 2.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  24 KYRPKDFTDLMVGQEpmVRTLTNAF-ETGRIAQAYMLTGVRGVGKTTTARILARALNYktseidkptidlrtpgehcqai 102
Cdd:PHA02544  14 KYRPSTIDECILPAA--DKETFKSIvKKGRIPNMLLHSPSPGTGKTTVAKALCNEVGA---------------------- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 103 megrhvDVIEMDAAShTGIDDIR-EIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTL-EEPPEHVKFIFATTEIR 180
Cdd:PHA02544  70 ------EVLFVNGSD-CRIDFVRnRLTRFASTVSLTGGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKN 142
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 517259200 181 KVPITVLSRCQRFDLRRISASDLVGLF-------TTIAAKEGIEAEADALA 224
Cdd:PHA02544 143 GIIEPLRSRCRVIDFGVPTKEEQIEMMkqmivrcKGILEAEGVEVDMKVLA 193
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
100-321 2.46e-09

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 59.11  E-value: 2.46e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 100 QAIMEGRHVDVIEMDAAShtgiDDIREIIEQVRYRPVSARYKVYIIDEVHMLS--TQAFNGLLKTLEEPPEHVKFIFATT 177
Cdd:COG1466   27 AALAEDDGFNRTRLDGAE----TDWAELLDEAQTLSLFGERRLVIVRNAEFLKkpGEGLEALEAYLANPPPDTVLVLTAG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 178 EI---RKVPITVLSRCQRFDLRRISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSardgLSLLDQAI------AHG 248
Cdd:COG1466  103 KLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERVGGD----LLALAQELeklalyAGD 178
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517259200 249 AGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLTDLADFTHLVTRLKYVPDA 321
Cdd:COG1466  179 GGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLLAEGEEPVLILAALARQFRLLLQVKALLAQ 251
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
55-198 3.09e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.84  E-value: 3.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200    55 QAYMLTGVRGVGKTTTARILARALNYKTSEIdkptIDLRTPGEHCQAiMEGRHVDVIEMDAASHTGIDDIREIIEQVRYR 134
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGPPGGGV----IYIDGEDILEEV-LDQLLLIIVGGKKASGSGELRLRLALALARKL 77
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517259200   135 pvsaRYKVYIIDEVHMLSTQAFNGLL-------KTLEEPPEHVKFIFATTEIRKVPITVLSR---CQRFDLRRI 198
Cdd:smart00382  78 ----KPDVLILDEITSLLDAEQEALLllleelrLLLLLKSEKNLTVILTTNDEKDLGPALLRrrfDRRIVLLLI 147
PRK13341 PRK13341
AAA family ATPase;
21-245 5.52e-09

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 59.30  E-value: 5.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  21 LARKYRPKDFTDLmVGQEPMV---RTLTNAFETGRIAQAyMLTGVRGVGKTTTARILARalnyktseidkptidlrtpge 97
Cdd:PRK13341  18 LADRLRPRTLEEF-VGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIAN--------------------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  98 HCQAimegrhvDVIEMDAASHtGIDDIREIIEQVRYRpvSARY---KVYIIDEVHMLSTQAFNGLLKTLEEPPehVKFIF 174
Cdd:PRK13341  75 HTRA-------HFSSLNAVLA-GVKDLRAEVDRAKER--LERHgkrTILFIDEVHRFNKAQQDALLPWVENGT--ITLIG 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 175 ATTE--IRKVPITVLSRCQRFDLRRISASDLVG-LFTTIAAKEG------IEAEADALAMIARAAEGSARDGLSLLDQAI 245
Cdd:PRK13341 143 ATTEnpYFEVNKALVSRSRLFRLKSLSDEDLHQlLKRALQDKERgygdrkVDLEPEAEKHLVDVANGDARSLLNALELAV 222
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
39-195 4.14e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 55.20  E-value: 4.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  39 PMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYKTSEiDKPTidlrtpG--EHCQAIMEGRHVD--VI--E 112
Cdd:PRK06090  10 PVWQNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQ-SEAC------GfcHSCELMQSGNHPDlhVIkpE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 113 MDAASHTgIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQR 192
Cdd:PRK06090  83 KEGKSIT-VEQIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQ 161

                 ...
gi 517259200 193 FDL 195
Cdd:PRK06090 162 WVV 164
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
57-193 5.38e-08

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 51.83  E-value: 5.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   57 YMLTGVRGVGKTTTARILARALNYKTSEIDKPTIDLRTPGEhcqaimegrhvdviemdaashtGIDDIREIIEQVRyrpv 136
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGE----------------------SEKRLRELFEAAK---- 54
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517259200  137 SARYKVYIIDEVHML-----------STQAFNGLLKTLEEP---PEHVKFIFATTEIRKVPITVLSRCQRF 193
Cdd:pfam00004  55 KLAPCVIFIDEIDALagsrgsggdseSRRVVNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRFDRI 125
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
121-249 1.59e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 53.61  E-value: 1.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 121 IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISA 200
Cdd:PRK06964 114 IEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPTILSRCRQFPMTVPAP 193
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 517259200 201 SDLVGLFTT--IAAKEGIEAEADA--LAMIArAAEGSARDGLSLLDQAIAHGA 249
Cdd:PRK06964 194 EAAAAWLAAqgVADADALLAEAGGapLAALA-LASDENRPLRDWTLGQLAAGA 245
AAA_22 pfam13401
AAA domain;
54-182 4.74e-07

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 49.26  E-value: 4.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   54 AQAYMLTGVRGVGKTTTARILARALNYKTSE---IDKPtiDLRTPGEHCQAIMEGrhvdvIEMDAASHTGIDDIREIIEQ 130
Cdd:pfam13401   5 AGILVLTGESGTGKTTLLRRLLEQLPEVRDSvvfVDLP--SGTSPKDLLRALLRA-----LGLPLSGRLSKEELLAALQQ 77
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 517259200  131 VRYRpvSARYKVYIIDEVHMLSTQAFNgLLKTLEEPPEH-VKFIFA-TTEIRKV 182
Cdd:pfam13401  78 LLLA--LAVAVVLIIDEAQHLSLEALE-ELRDLLNLSSKlLQLILVgTPELREL 128
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
97-193 1.11e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 50.60  E-value: 1.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  97 EHCQAIMEGRHVDVIEM-DAASHTGIDDIREIIEQVRYRPVSAR-YKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIF 174
Cdd:PRK05818  44 ESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINKLNRPSVESNgKKIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIF 123
                         90
                 ....*....|....*....
gi 517259200 175 ATTEIRKVPITVLSRCQRF 193
Cdd:PRK05818 124 TTRNENNILNTILSRCVQY 142
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
121-196 5.46e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 47.72  E-value: 5.46e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517259200 121 IDDIREIIEQVrYrpVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLR 196
Cdd:PRK08485  39 IEDAKEVIAEA-Y--IAESEEKIIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRK 111
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
210-261 6.96e-05

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 41.30  E-value: 6.96e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 517259200 210 IAAKEGIEAEADALAMIARAAEGSARDGLSLLDQAIAHG-AGVVQAEAVRGML 261
Cdd:cd18133   13 IAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGdDGKISLDRVYQAV 65
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
198-257 2.01e-04

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 39.82  E-value: 2.01e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 198 ISASDLVGLFTTIAAKEGIEAEADALAMIARAAEGSARDGLSLLdQAIAHGAGVVQAEAV 257
Cdd:cd18140    1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDV 59
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
58-159 6.78e-04

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 41.70  E-value: 6.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  58 MLTGVRGVGKTTTARILARAL--NYKTSEIDKPTIdlrTPGEHCQAIMEGRHVDVIEMDAAShtGIDDIREIIEQVRyrp 135
Cdd:COG3267   47 VLTGEVGTGKTTLLRRLLERLpdDVKVAYIPNPQL---SPAELLRAIADELGLEPKGASKAD--LLRQLQEFLLELA--- 118
                         90       100
                 ....*....|....*....|....*
gi 517259200 136 vSARYKVY-IIDEVHMLSTQAFNGL 159
Cdd:COG3267  119 -AAGRRVVlIIDEAQNLPPETLEEL 142
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
107-196 7.61e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 41.75  E-value: 7.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 107 HVDVIEMDAASHT---GIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVP 183
Cdd:PRK06581  54 HFIARETSATSNAkniSIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASII 133
                         90
                 ....*....|...
gi 517259200 184 ITVLSRCQRFDLR 196
Cdd:PRK06581 134 STIRSRCFKINVR 146
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
49-231 1.40e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 41.16  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  49 ETGRIAQAYMLTGvrGVGKTTTARILARALNYKTSEIDKPTIDLRTpgehCQAIMEGRHVDVIEMDAASHT-GIDDIREI 127
Cdd:PRK07276  19 EQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRS----CRLIEQGEFSDVTVIEPQGQViKTDTIREL 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 128 IEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASdLVGLf 207
Cdd:PRK07276  93 VKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFPKNEAY-LIQL- 170
                        170       180
                 ....*....|....*....|....*
gi 517259200 208 ttiAAKEGI-EAEADALAMIARAAE 231
Cdd:PRK07276 171 ---LEQKGLlKTQAELLAKLAQSTS 192
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
59-81 1.86e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 39.08  E-value: 1.86e-03
                         10        20
                 ....*....|....*....|...
gi 517259200  59 LTGVRGVGKTTTARILARALNYK 81
Cdd:cd00464    4 LIGMMGAGKTTVGRLLAKALGLP 26
holA TIGR01128
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ...
159-352 2.88e-03

DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273455 [Multi-domain]  Cd Length: 302  Bit Score: 39.94  E-value: 2.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  159 LLKTLEEPPEHVKFIF----------ATTEIRKVPITVLSRCQRfdlrrISASDLVGLFTTIAAKEGIEAEADALAMIAR 228
Cdd:TIGR01128  67 LEEYLANPPPDTLLLIeapkldkrkkLTKWLKALKNAEIVECKT-----PKEQELPRWIQARLKKLGLRIDPDAVQLLAE 141
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  229 AAEGSardgLSLLDQAIA-----HGAGVVQAEAVRGMLGLADRARIVDLFQHIVKGDVAAALGEFQNQYEAGANPVVVLT 303
Cdd:TIGR01128 142 LVEGN----LLAIAQELEklalyAPDGKITLEDVEEAVSDSARFNVFDLTDALLEGKAARALRILKGLLGEGEEPLILLA 217
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 517259200  304 DLADFTHLVTRLKyvpdaandpSLSEVERTKAAEFAKGvavttlsRIWQ 352
Cdd:TIGR01128 218 LLQRQLRLLLQLK---------RLAQQGGPLAQLASKL-------GIWP 250
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
56-205 4.05e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 37.95  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   56 AYMLTGVRGVGKTTTARILARALNYKTSEIdkpTIDLRTPgehcqaimegrhvdviemDAASHTGIDDIREIIEQVRYRP 135
Cdd:pfam13173   4 ILVITGPRQVGKTTLLLQLIKELLPPENIL---YINLDDP------------------RLLKLADFELLELFLELLYPGK 62
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  136 vsaryKVYIIDEVHMlstqafngllktLEEPPEHVKFIFATTEIRKVpitVLSRCQRFDLRRISASDLVG 205
Cdd:pfam13173  63 -----TYLFLDEIQR------------VPDWELALKRLYDDGPNGRV---ILTGSSALLLSKEIAESLAG 112
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
58-236 4.69e-03

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 39.89  E-value: 4.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  58 MLTGVRGVGKTTTARILARALNyktseidkptidlrtpgehcqaimegrhVDVIEMDAAS-------HTGIDdIREIIEQ 130
Cdd:COG0464  195 LLYGPPGTGKTLLARALAGELG----------------------------LPLIEVDLSDlvskyvgETEKN-LREVFDK 245
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 131 VR-YRPVsarykVYIIDEVHML-----------STQAFNGLLKTLEEPPEHVKFIFATTEIRKVPITVLSRCQR-FDLRR 197
Cdd:COG0464  246 ARgLAPC-----VLFIDEADALagkrgevgdgvGRRVVNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFDEiIFFPL 320
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 517259200 198 ISASDLVGLFTTIAAKEGIEAEADaLAMIARAAEG-SARD 236
Cdd:COG0464  321 PDAEERLEIFRIHLRKRPLDEDVD-LEELAEATEGlSGAD 359
AAA_18 pfam13238
AAA domain;
58-143 4.80e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.41  E-value: 4.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200   58 MLTGVRGVGKTTTARILARALNYKTSEID-KPTIDLRTPGEH----CQAIMEGRHVDVIE--MDAASHTGIDDIreIIEQ 130
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGFGDNVRDlALENGLVLGDDPetreSKRLDEDKLDRLLDllEENAALEEGGNL--IIDG 79
                          90
                  ....*....|...
gi 517259200  131 VRYRPVSARYKVY 143
Cdd:pfam13238  80 HLAELEPERAKDL 92
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
56-151 6.71e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 39.16  E-value: 6.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  56 AYMLTGVRGVGKTTTARILARALNyktseiDKPTIDLrtpgehcqaimegrhvdviEMDAASHTGIDDIREIIEqvRYRP 135
Cdd:COG1373   22 AVVITGPRQVGKTTLLKQLAKELE------NILYINL-------------------DDPRLRALAEEDPDDLLE--ALKE 74
                         90
                 ....*....|....*.
gi 517259200 136 VSARYKVYIIDEVHML 151
Cdd:COG1373   75 LYPGKTYLFLDEIQRV 90
COG2842 COG2842
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ...
41-247 7.91e-03

Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];


Pssm-ID: 442090 [Multi-domain]  Cd Length: 254  Bit Score: 38.39  E-value: 7.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200  41 VRTLTNAFETGRIAQAYML-TGVRGVGKTTTARILARAlnyktseiDKPTI-----DLRTPGEHCQAIMEgrhvdVIEMD 114
Cdd:COG2842   36 VRRFAEALDEARALPGIGVvYGESGVGKTTAAREYANR--------NPNVIyvtasPSWTSKELLEELAE-----ELGIP 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517259200 115 AASHTGIDDIREIIEQVRY--RPVsarykvyIIDEVHMLSTQAFngllktleeppEHVKFIFATTEIrkvPI-------- 184
Cdd:COG2842  103 APPGTIADLRDRILERLAGtgRLL-------IIDEADHLKPKAL-----------EELRDIHDETGV---GVvligmerl 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517259200 185 -TVLSRCQRFD--------LRRISASDlvgLFTTIAAKEGIEaEADALAMIARAAEGSARdglsLLDQAIAH 247
Cdd:COG2842  162 pAKLKRYEQLYsrigfwveFKPLSLED---VRALAEAWGELT-DPDLLELLHRITRGNLR----RLDRTLRL 225
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
35-79 8.48e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 37.48  E-value: 8.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 517259200   35 VGQEPMVRTLTNAFETGRI--AQAYMLTGVRGVGKTTTARILARALN 79
Cdd:pfam13191   3 VGREEELEQLLDALDRVRSgrPPSVLLTGEAGTGKTTLLRELLRALE 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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