NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|517055082|ref|WP_018243900|]
View 

MULTISPECIES: ABC transporter permease [Rhizobium]

Protein Classification

ABC transporter permease( domain architecture ID 10003093)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 16-284 4.27e-52

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


:

Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 172.25  E-value: 4.27e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  16 RRDAALTLGPALLVFAFGFLSPLINLAIESlkeFTPGRVGSVENAAATVQNYYE-LANQAFASVLLTTFWIGGVAAIIGQ 94
Cdd:COG1176    8 RLRPLLLLLPALLWLLLFFVLPLLLLLVYS---FTTRDPYGGVVPGFTLENYARlFTDPLYLKVLLRTLWIALLTTLICL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  95 LVAFPLAYFIVRRiSPRMRALTLGFLITLVLSSVLIKTYAIELTFGSVGILRPLLLTL--GLSPNSREYINIVVTAGLVH 172
Cdd:COG1176   85 LLGYPIAYFLARA-PPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALglIDEPLRLLYTEFAVVIGLVY 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 173 SIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLFISNV 252
Cdd:COG1176  164 VYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNL 243

                        250       260       270
                 ....*....|....*....|....*....|..
gi 517055082 253 IYTRFSDIANYPSGAAISLVMLTAALAVVAVI 284
Cdd:COG1176  244 IYQQFLSALNWPLAAALAVVLLLIVLLVLLLY 275
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 16-284 4.27e-52

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 172.25  E-value: 4.27e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  16 RRDAALTLGPALLVFAFGFLSPLINLAIESlkeFTPGRVGSVENAAATVQNYYE-LANQAFASVLLTTFWIGGVAAIIGQ 94
Cdd:COG1176    8 RLRPLLLLLPALLWLLLFFVLPLLLLLVYS---FTTRDPYGGVVPGFTLENYARlFTDPLYLKVLLRTLWIALLTTLICL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  95 LVAFPLAYFIVRRiSPRMRALTLGFLITLVLSSVLIKTYAIELTFGSVGILRPLLLTL--GLSPNSREYINIVVTAGLVH 172
Cdd:COG1176   85 LLGYPIAYFLARA-PPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALglIDEPLRLLYTEFAVVIGLVY 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 173 SIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLFISNV 252
Cdd:COG1176  164 VYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNL 243

                        250       260       270
                 ....*....|....*....|....*....|..
gi 517055082 253 IYTRFSDIANYPSGAAISLVMLTAALAVVAVI 284
Cdd:COG1176  244 IYQQFLSALNWPLAAALAVVLLLIVLLVLLLY 275
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 63-280 2.68e-26

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 104.77  E-value: 2.68e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  63 TVQNYYELANQAFASVLLTTFWIGGVAAIIGQLVAFPLAYFIVRrISPRMRALTLGFLITLVLSSVLIKTYAIELTFGSV 142
Cdd:PRK09497  49 TLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAK-LPHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTK 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 143 GIL--RPLLLTLGLSPNSREYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPAL 220
Cdd:PRK09497 128 GYLneFLLWLGVIDTPIRIMFTESAVIIGLVYILLPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGI 207

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 221 ISSTLVSLTFAISAFVIPMVLGRGRVLFISNVIYTRFSDIANYPSGAAISlVMLTAALAV 280
Cdd:PRK09497 208 IAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAATS-ITLTIVMGL 266
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 70-289 1.77e-12

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 67.40  E-value: 1.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082   70 LANQAFASVLLTTFWIGGVAAIIGQLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLiktYAIELT--FGSVGILRP 147
Cdd:TIGR03262  47 FATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLL---PAISLIylFGNQGLLKG 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  148 LLLTLGLspnsreYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVS 227
Cdd:TIGR03262 124 LLGGFSI------YGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVV 197

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517055082  228 LTFAISAFVIPMVLGrGRVLFISNVIYTRFSDIANYPSGAAISLVMLTAALAVVAVITFAQA 289
Cdd:TIGR03262 198 FTLVITDFGVPKVIG-GDYNVLATDIYKQVIGQQNFPMGAVVGVLLLLPALLAFGIDRAIQR 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-280 8.98e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 51.13  E-value: 8.98e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  79 LLTTFWIGGVAAIIGQLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLIktyaieltfgsvGILRPLLLTLGLSPNS 158
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVL------------GLLLVLLFGVLLGWGI 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 159 REYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIP 238
Cdd:cd06261   69 LPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 517055082 239 MVLGRGRVLFISNVIYTRFSDIANYPSGAAISLVMLTAALAV 280
Cdd:cd06261  149 SFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 173-290 2.21e-03

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 38.43  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  173 SIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLfisNV 252
Cdd:pfam00528  62 GWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL---GL 138

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 517055082  253 IYTRFSDIANYPSGAAISLVMLTAALAVVAVITFAQAW 290
Cdd:pfam00528 139 LLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRL 176
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 16-284 4.27e-52

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 172.25  E-value: 4.27e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  16 RRDAALTLGPALLVFAFGFLSPLINLAIESlkeFTPGRVGSVENAAATVQNYYE-LANQAFASVLLTTFWIGGVAAIIGQ 94
Cdd:COG1176    8 RLRPLLLLLPALLWLLLFFVLPLLLLLVYS---FTTRDPYGGVVPGFTLENYARlFTDPLYLKVLLRTLWIALLTTLICL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  95 LVAFPLAYFIVRRiSPRMRALTLGFLITLVLSSVLIKTYAIELTFGSVGILRPLLLTL--GLSPNSREYINIVVTAGLVH 172
Cdd:COG1176   85 LLGYPIAYFLARA-PPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALglIDEPLRLLYTEFAVVIGLVY 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 173 SIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLFISNV 252
Cdd:COG1176  164 VYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNL 243

                        250       260       270
                 ....*....|....*....|....*....|..
gi 517055082 253 IYTRFSDIANYPSGAAISLVMLTAALAVVAVI 284
Cdd:COG1176  244 IYQQFLSALNWPLAAALAVVLLLIVLLVLLLY 275
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 63-280 2.68e-26

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 104.77  E-value: 2.68e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  63 TVQNYYELANQAFASVLLTTFWIGGVAAIIGQLVAFPLAYFIVRrISPRMRALTLGFLITLVLSSVLIKTYAIELTFGSV 142
Cdd:PRK09497  49 TLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAK-LPHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTK 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 143 GIL--RPLLLTLGLSPNSREYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPAL 220
Cdd:PRK09497 128 GYLneFLLWLGVIDTPIRIMFTESAVIIGLVYILLPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGI 207

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 221 ISSTLVSLTFAISAFVIPMVLGRGRVLFISNVIYTRFSDIANYPSGAAISlVMLTAALAV 280
Cdd:PRK09497 208 IAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAATS-ITLTIVMGL 266
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-283 4.53e-26

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 107.17  E-value: 4.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  12 SIPDRRDAALTLGPALLVFAFgFLSPLINLAIESLkeftpgrVGSVENAAATvqnyyeLANQAFASVLLTTFWIGGVAAI 91
Cdd:COG1178    3 TRPRRRPRLLLLLLALLLALL-VLLPLLALLLRAF-------TDGLANFWAL------LSDPYLWRALGNTLLLALLVTL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  92 IGQLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLIkTYAIELTFGSVGILRPLLLTLG--LSPNSREYINIVVTAG 169
Cdd:COG1178   69 LSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVV-ALAWIALFGPNGLLNTLLRALFglEPPDIYGLGGIILVLV 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 170 LVHsiIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGrGRVLFI 249
Cdd:COG1178  148 LFN--YPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLG-GGYTTL 224

                        250       260       270
                 ....*....|....*....|....*....|....
gi 517055082 250 SNVIYTRFSDIANYPSGAAISLVMLTAALAVVAV 283
Cdd:COG1178  225 TTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLL 258
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 26-294 2.69e-19

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 85.16  E-value: 2.69e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  26 ALLVFAFgFLSPLINLAIESlkeFTPGRVGSVENAAATVQNYYEL-ANQAFASVLLTTFWIGGVAAIIGQLVAFPLAYFI 104
Cdd:COG1177   13 LALVLLF-LYLPILVLVLYS---FNDSWFLTFPPEGFTLRWYAELfSDPRLLDALLNSLLIALLSTLLATVLGTPAALAL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 105 VRRISPRMRALTLGFLITLVLSSVLIkTYAIELTFGSVGILrpllltlglspnsreyiNIVVTAGLVHSI--IPVATLTL 182
Cdd:COG1177   89 ARYRFRGRRLLLALLLLPLVVPGIVL-GVALLLLFSALGLS-----------------GGLWGLILAHVVftLPFVVLVV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 183 IGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLFISNVIYTRFSDiAN 262
Cdd:COG1177  151 LARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYIYSMIRR-GI 229

                        250       260       270
                 ....*....|....*....|....*....|..
gi 517055082 263 YPSGAAISLVMLTAALAVVAVITFAQAWKVSR 294
Cdd:COG1177  230 SPEINALSTLLILLSLLLLLLAERLRRRGERR 261
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
1-284 3.36e-19

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 87.14  E-value: 3.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082   1 MTKVRRQPVAISIPDRRDAALTLgpALLVFAFGFLSPLINLAIESLKEFTPGrvgsvenaAATVQNY-YELANQAFASVL 79
Cdd:COG1178  271 VGGRARRPRRVKLGRWRWLALAL--CLLLVLLGLLLPLLALLLWSLTKALDD--------NLTLDNYrFVLLDPSLLRAL 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  80 LTTFWIGGVAAIIGQLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLIktyaieltfgsvGILRPLLLTLGLSPNSR 159
Cdd:COG1178  341 LNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVL------------GLGLLLLFNRPLPLLLY 408

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 160 EYINIVVTAGLVHSIiPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPM 239
Cdd:COG1178  409 GTLAILVLAYVVRFL-PFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATL 487

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 517055082 240 VLGRGRVLFISNVIYTRFSDiANYPSGAAISLVMLTAALAVVAVI 284
Cdd:COG1178  488 LLRPPGFETLAVLIYQLASS-GRYGEAAALALLLVLVSLLPVLLL 531
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
2-294 1.02e-17

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 81.33  E-value: 1.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082   2 TKVRRQPVAISIPDRRDAALTLGPALLVFAFGFLSPLINLAIESlkeFTPGRVGSVENAAATVQNYYEL-ANQAFASVLL 80
Cdd:COG1175    3 TTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLS---FTDWNLLGPPPEFVGLDNYARLfTDPRFWNALG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  81 TTFWIGGVAAIIGQLVAFPLAYFIVRRIspRMRaltlGFLITLVLSSVLIKTYAIELTF-----GSVGILRPLLLTLGLS 155
Cdd:COG1175   80 NTLLFTVVSVPLQLVLGLLLALLLNRKL--RGR----GFFRTLFFLPWVISPVVVALIWkwlfnPDYGLLNALLGALGLE 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 156 P----NSREYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFA 231
Cdd:COG1175  154 PinwlGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGA 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517055082 232 ISAFVIPMVLGRG----RVLFISNVIYTRFSDIANYPSGAAISLVMltaaLAVVAVITFAQAWKVSR 294
Cdd:COG1175  234 LQVFDLVYVLTGGgpgnSTTTLVLYIYQTAFQQFDFGYASAIAVVL----FLIILVLTLLQLRLLRR 296
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 21-290 1.41e-12

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 66.31  E-value: 1.41e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  21 LTLGPALLVFAFGFLSPLINLAIESLkEFTPGRVGSVenaaatvqnyyeLANQAFASVLLTTFWIGGVAAIIGQLVAFPL 100
Cdd:COG0555   11 LTLGLTLLYLSLIVLLPLAALVLKAA-GLGWAEFWAV------------LTSPRVLAALKLSLGTALIAALINLVFGLPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 101 AYFIVRRISPRMRALTLGFLITLVLSSVLIkTYAIELTFGSVGILRPLLLTLGlspnsreyINIV-----VTAGLVHSII 175
Cdd:COG0555   78 AWVLVRYRFPGKRLVDALVDLPFALPTAVA-GIALLLLFGPNGWLGQLLAPLG--------IKVAftplgIVLAQTFVSL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 176 PVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAF--VIpMVLG--RGRVLFISN 251
Cdd:COG0555  149 PFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFgaVI-FIAGnlPMKTEILPL 227

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 517055082 252 VIYTRFSDIaNYPSGAAISLVMLTAALAVVAVITFAQAW 290
Cdd:COG0555  228 LIYLKLEEG-DYAGATAIALVLLLISFLLLLLINLLQRR 265
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 70-289 1.77e-12

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 67.40  E-value: 1.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082   70 LANQAFASVLLTTFWIGGVAAIIGQLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLiktYAIELT--FGSVGILRP 147
Cdd:TIGR03262  47 FATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLL---PAISLIylFGNQGLLKG 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  148 LLLTLGLspnsreYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVS 227
Cdd:TIGR03262 124 LLGGFSI------YGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVV 197

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517055082  228 LTFAISAFVIPMVLGrGRVLFISNVIYTRFSDIANYPSGAAISLVMLTAALAVVAVITFAQA 289
Cdd:TIGR03262 198 FTLVITDFGVPKVIG-GDYNVLATDIYKQVIGQQNFPMGAVVGVLLLLPALLAFGIDRAIQR 258
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 14-283 2.09e-12

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 66.18  E-value: 2.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  14 PDRRDAALTLGPALLVFAFGFLSPLINLAIESLkefTPGRVGSVENAAATvqnyyeLANQAFASVLLTTFWIGGVAAIIG 93
Cdd:PRK15050  19 RRRLRPLLWLLLPLLVLAPLVVYPLVRVVLQSL---TGEHGLGLATYRAV------LGSPDFRGALLTTLQIAFASTAGC 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  94 QLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLIktyAIELTF-----GSVGILRPLLLTLGLSPNSREYINIVVTA 168
Cdd:PRK15050  90 LVLGVLLALVLAFVPFPGASLVGRFIDTFVAFPSFLI---TLAFTFlygsaGSVNIALQRLFGLEAPPLDFLYSPGGVIL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 169 GLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLF 248
Cdd:PRK15050 167 AEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVT 246

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 517055082 249 ISNVIYTRFSDIANYPSGAAISLVMLTAALAVVAV 283
Cdd:PRK15050 247 LPVLIYSKAIVDFDYPTACAIAVVNLALSLGLYAL 281
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 80-286 7.43e-11

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 61.65  E-value: 7.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  80 LTTFWIGGVAAIIGQLVAFPLAYFIVRRiSPRMRALTLGFLITLVLSSVLIKTYAIELTFGSVGIL--RPLLLTLGLSPN 157
Cdd:PRK10683 100 LQSLQVAAISTLCCLLIGYPLAWAVAHS-KPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLnnFLLWLGVIDQPL 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 158 SREYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVI 237
Cdd:PRK10683 179 TILHTNLAVYIGIVYAYLPFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVI 258

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 517055082 238 PMVLGRGRVLFISNVIYTRFSDIANYPSGAAISLVMLTaaLAVVAVITF 286
Cdd:PRK10683 259 PELLGGPDSIMIGRVLWQEFFNNRDWPVASAVAIIMLL--LLIVPIMWF 305
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 74-294 1.68e-09

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 56.60  E-value: 1.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  74 AFASVLLTTFWIGGVAAIIGQLVAFPLAYFIVRRISPRMRALT-------------LGFLITLVLS------SVLIKTYA 134
Cdd:COG4149    4 EDWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEalvtlplvlpptvLGFYLLLLFGrngplgQLLEELFG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 135 IELTFGSVGilrpllltlglspnsreyiniVVTAGLVHSIiPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLP 214
Cdd:COG4149   84 ISLVFTWTG---------------------AVLASVVVSL-PLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLP 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 215 LSFPALISSTL-----------VSLTFAISafvIPmvlGRGRVLFISnvIYTRFSDiANYPSGAAISLVMLTAALAVVAV 283
Cdd:COG4149  142 LAKPGILAGAVlafaralgefgATLMFAGN---IP---GKTQTLPLA--IYDAVEA-GDYAAAHALSLILLAISFVVLLL 212

                        250
                 ....*....|.
gi 517055082 284 ITFAQAWKVSR 294
Cdd:COG4149  213 LNLLNRRRRRR 223
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-280 8.98e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 51.13  E-value: 8.98e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  79 LLTTFWIGGVAAIIGQLVAFPLAYFIVRRISPRMRALTLGFLITLVLSSVLIktyaieltfgsvGILRPLLLTLGLSPNS 158
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVL------------GLLLVLLFGVLLGWGI 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 159 REYINIVVTAGLVHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIP 238
Cdd:cd06261   69 LPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 517055082 239 MVLGRGRVLFISNVIYTRFSDIANYPSGAAISLVMLTAALAV 280
Cdd:cd06261  149 SFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 26-241 1.48e-07

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 51.63  E-value: 1.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  26 ALLVFAFGFLSPLINLAIESLKefTPGRVGSVENAA----ATVQNYYELANQA-FASVLLTTFWIGGVAAIIGQLVAFPL 100
Cdd:COG0395   20 LLILLALLFLFPLYWMVVTSFK--PPAEIFSGPPSLlpseFTLENYRAAFTDGpFGRYLLNSLIVAVVSTVLSLLLSSLA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 101 AYFIVRRISPRMRALTLGFLITLVLS--SVLIKTYaieLTFGSVGILrpllltlglspNSREYINIVVTAGLvhsiIPVA 178
Cdd:COG0395   98 AYALARFRFRGRKLLFLLILATLMIPgqVLLIPLY---LLFRQLGLL-----------NTYWGLILPYLAFG----LPFG 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517055082 179 TLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVL 241
Cdd:COG0395  160 IFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLIL 222
modB PRK09421
molybdate ABC transporter permease subunit;
185-284 3.24e-06

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 47.22  E-value: 3.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 185 AMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFvipmvlgRGRVLFISNVI-YTRFSDIANY 263
Cdd:PRK09421 114 SLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEF-------GATITFVSNIPgETQTIPSAMY 186

                         90       100
                 ....*....|....*....|....*...
gi 517055082 264 -----PSG--AAISLVMLTAALAVVAVI 284
Cdd:PRK09421 187 tliqtPGGesAAARLCIISIAIALASLL 214
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 175-236 6.85e-05

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 43.43  E-value: 6.85e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517055082 175 IPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFA-----ISAFV 236
Cdd:PRK09500 139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSlddvvVSSFV 205
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
 176-246 3.69e-04

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 41.78  E-value: 3.69e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517055082 176 PVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRV 246
Cdd:COG4135  439 PYVFLSLAGPWRALDPRYAQVAASLGASPWRVFWRVKLPLLLRPILTAAAVGFAVSVAQYLPTLLIGAGRV 509
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
175-289 5.08e-04

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 40.89  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082 175 IPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFvipmvlgrGRVLFI----- 249
Cdd:PRK10971 152 IPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEF--------GAVIFIagnia 223

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 517055082 250 ------SNVIYTRFSDIaNYPSGAAISLVMLTAALAVVAVITFAQA 289
Cdd:PRK10971 224 wktevtSLMIFVRLQEF-DYPAASAIASVILAASLLLLFSINTLQS 268
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 173-290 2.21e-03

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 38.43  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517055082  173 SIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAISAFVIPMVLGRGRVLfisNV 252
Cdd:pfam00528  62 GWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL---GL 138

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 517055082  253 IYTRFSDIANYPSGAAISLVMLTAALAVVAVITFAQAW 290
Cdd:pfam00528 139 LLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRL 176
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 171-232 8.25e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 37.05  E-value: 8.25e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517055082 171 VHSIIPVATLTLIGAMQSIDPRLLDAAQSLGAPGWRAHLSITLPLSFPALISSTLVSLTFAI 232
Cdd:COG0600  133 FLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAW 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH