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Conserved domains on  [gi|517053978|ref|WP_018242796|]
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MULTISPECIES: nitrile hydratase accessory protein [Rhizobium]

Protein Classification

nitrile hydratase accessory protein( domain architecture ID 10024036)

nitrile hydratase accessory protein plays a role in maturation or activation of the alpha and beta subunits of nitrile hydratase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
nitrile_acc TIGR03889
nitrile hydratase accessory protein; Members of this protein family are found in operons with ...
 25-94 5.27e-29

nitrile hydratase accessory protein; Members of this protein family are found in operons with the alpha and beta subunits of nitrile hydratase, an enzyme with Fe(III) or Co(III) at the active site, and appear to be accessory proteins for maturation or activation of the enzyme. This protein is homologous to the beta subunit (see TIGR03888).


:

Pssm-ID: 188404  Cd Length: 74  Bit Score: 100.19  E-value: 5.27e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517053978   25 FPEPWAAEAFAMTVHLHAKGLFSWSEWAETLSAQLHKPG--RAEDGSD-YFDCWVAALSDLIVNRGIADADTI 94
Cdd:TIGR03889   1 FDEPWQAQAFALTVHLHEAGLFPWSEWAERLSAAIKRAGasRGLDGGDdYYDHWLAALERLVVELGLAAPEDI 73
 
Name Accession Description Interval E-value
nitrile_acc TIGR03889
nitrile hydratase accessory protein; Members of this protein family are found in operons with ...
 25-94 5.27e-29

nitrile hydratase accessory protein; Members of this protein family are found in operons with the alpha and beta subunits of nitrile hydratase, an enzyme with Fe(III) or Co(III) at the active site, and appear to be accessory proteins for maturation or activation of the enzyme. This protein is homologous to the beta subunit (see TIGR03888).


Pssm-ID: 188404  Cd Length: 74  Bit Score: 100.19  E-value: 5.27e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517053978   25 FPEPWAAEAFAMTVHLHAKGLFSWSEWAETLSAQLHKPG--RAEDGSD-YFDCWVAALSDLIVNRGIADADTI 94
Cdd:TIGR03889   1 FDEPWQAQAFALTVHLHEAGLFPWSEWAERLSAAIKRAGasRGLDGGDdYYDHWLAALERLVVELGLAAPEDI 73
NHase_beta pfam02211
Nitrile hydratase beta subunit; Nitrile hydratases EC:4.2.1.84 are unusual metalloenzymes that ...
 22-96 7.43e-06

Nitrile hydratase beta subunit; Nitrile hydratases EC:4.2.1.84 are unusual metalloenzymes that catalyze the hydration of nitriles to their corresponding amides. They are used as biocatalysts in acrylamide production, one of the few commercial scale bioprocesses, as well as in environmental remediation for the removal of nitriles from waste streams. Nitrile hydratases are composed of two subunits, alpha and beta, and they contain one iron atom per alpha beta unit.


Pssm-ID: 426662  Cd Length: 223  Bit Score: 43.00  E-value: 7.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517053978   22 EPVFPEPWAAEAFAMTVHLHAKGLFSWSE---------WAETLSAQlhkpgraedgsdYFDCWVAALSDLIVNRGIADAD 92
Cdd:pfam02211  22 EPVFHEEWEKRAFALTLAMGALGAWNLDEsrhgrermgPADYLRSS------------YYEKWLGGIERLLVEKGVITPA 89


                  ....
gi 517053978   93 TIQA 96
Cdd:pfam02211  90 ELDA 93
 
Name Accession Description Interval E-value
nitrile_acc TIGR03889
nitrile hydratase accessory protein; Members of this protein family are found in operons with ...
 25-94 5.27e-29

nitrile hydratase accessory protein; Members of this protein family are found in operons with the alpha and beta subunits of nitrile hydratase, an enzyme with Fe(III) or Co(III) at the active site, and appear to be accessory proteins for maturation or activation of the enzyme. This protein is homologous to the beta subunit (see TIGR03888).


Pssm-ID: 188404  Cd Length: 74  Bit Score: 100.19  E-value: 5.27e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517053978   25 FPEPWAAEAFAMTVHLHAKGLFSWSEWAETLSAQLHKPG--RAEDGSD-YFDCWVAALSDLIVNRGIADADTI 94
Cdd:TIGR03889   1 FDEPWQAQAFALTVHLHEAGLFPWSEWAERLSAAIKRAGasRGLDGGDdYYDHWLAALERLVVELGLAAPEDI 73
nitrile_beta TIGR03888
nitrile hydratase, beta subunit; Members of this protein family are the beta subunit of ...
 22-99 2.99e-06

nitrile hydratase, beta subunit; Members of this protein family are the beta subunit of nitrile hydratase. The alpha subunit is represented by model TIGR01323. While nitrile hydratase is given the specific EC number 4.2.1.84, nitriles are a class of compounds, and one genome may carry more than one nitrile hydratase. The enzyme occurs in both non-heme iron and non-corrin cobalt forms. [Energy metabolism, Amino acids and amines]


Pssm-ID: 274835  Cd Length: 223  Bit Score: 44.36  E-value: 2.99e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517053978   22 EPVFPEPWAAEAFAMTVHLHAKGLFSWSEW---AETLSAQLHKpgraedGSDYFDCWVAALSDLIVNRGIADADTIQALQ 98
Cdd:TIGR03888  22 KPVFHAEWEKRAFAMFAAAGALGAFNIDEVrhgIERMNPADYL------ESSYYEKWVIGVATLLVEKGYLTEDELDERA 95


                  .
gi 517053978   99 Q 99
Cdd:TIGR03888  96 G 96
NHase_beta pfam02211
Nitrile hydratase beta subunit; Nitrile hydratases EC:4.2.1.84 are unusual metalloenzymes that ...
 22-96 7.43e-06

Nitrile hydratase beta subunit; Nitrile hydratases EC:4.2.1.84 are unusual metalloenzymes that catalyze the hydration of nitriles to their corresponding amides. They are used as biocatalysts in acrylamide production, one of the few commercial scale bioprocesses, as well as in environmental remediation for the removal of nitriles from waste streams. Nitrile hydratases are composed of two subunits, alpha and beta, and they contain one iron atom per alpha beta unit.


Pssm-ID: 426662  Cd Length: 223  Bit Score: 43.00  E-value: 7.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517053978   22 EPVFPEPWAAEAFAMTVHLHAKGLFSWSE---------WAETLSAQlhkpgraedgsdYFDCWVAALSDLIVNRGIADAD 92
Cdd:pfam02211  22 EPVFHEEWEKRAFALTLAMGALGAWNLDEsrhgrermgPADYLRSS------------YYEKWLGGIERLLVEKGVITPA 89


                  ....
gi 517053978   93 TIQA 96
Cdd:pfam02211  90 ELDA 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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