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Conserved domains on  [gi|516376670|ref|WP_017766703|]
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MULTISPECIES: type IVa pilus ATPase TapW [Aeromonas]

Protein Classification

PilT/PilU family type 4a pilus ATPase( domain architecture ID 11472029)

PilT/PilU family type 4a pilus ATPase is a hexameric ATPase that drives pilus retraction, which provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PilU COG5008
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
1-369 0e+00

Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];


:

Pssm-ID: 444032  Cd Length: 370  Bit Score: 713.02  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   1 MELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLPQIGR 80
Cdd:COG5008    1 MDLEDLLKLMVEKKASDLFITAGAPPSIKIDGKLTPLSQQPLTPEQVRELAYSIMNEEQREEFERTKECNFAISLPGVGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  81 FRINIFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIED 160
Cdd:COG5008   81 FRVNAFRQRGSVGMVLRRIETEIPTLDELGLPPVLKDLIMEKRGLVLFVGATGSGKSTTLAAMIDHRNENSSGHILTIED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 161 PVEFVHRHRKSIINQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRI 240
Cdd:COG5008  161 PIEFVHKHKKSIVTQREVGVDTESYEVALKNALRQAPDVILIGEIRDRETMEHAIAFAETGHLCLATLHANNANQALDRI 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 241 INFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDGGRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSAL 320
Cdd:COG5008  241 INFFPEERRPQLLMDLSLNLRAIVSQRLVPTKDGGRVAAVEVLLNTPLIADLIRKGEIHEIKEAMEKSRELGMQTFDQAL 320

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 516376670 321 FDLVVEGVIDEEEAVKNADSANNLRLKIKLW-KEKGQIASSSDATGWSLE 369
Cdd:COG5008  321 FRLYEAGKISYEEALRNADSANNLRLRIKLGsEGAAKADLDAGFDGLTLD 370
 
Name Accession Description Interval E-value
PilU COG5008
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
1-369 0e+00

Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];


Pssm-ID: 444032  Cd Length: 370  Bit Score: 713.02  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   1 MELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLPQIGR 80
Cdd:COG5008    1 MDLEDLLKLMVEKKASDLFITAGAPPSIKIDGKLTPLSQQPLTPEQVRELAYSIMNEEQREEFERTKECNFAISLPGVGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  81 FRINIFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIED 160
Cdd:COG5008   81 FRVNAFRQRGSVGMVLRRIETEIPTLDELGLPPVLKDLIMEKRGLVLFVGATGSGKSTTLAAMIDHRNENSSGHILTIED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 161 PVEFVHRHRKSIINQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRI 240
Cdd:COG5008  161 PIEFVHKHKKSIVTQREVGVDTESYEVALKNALRQAPDVILIGEIRDRETMEHAIAFAETGHLCLATLHANNANQALDRI 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 241 INFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDGGRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSAL 320
Cdd:COG5008  241 INFFPEERRPQLLMDLSLNLRAIVSQRLVPTKDGGRVAAVEVLLNTPLIADLIRKGEIHEIKEAMEKSRELGMQTFDQAL 320

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 516376670 321 FDLVVEGVIDEEEAVKNADSANNLRLKIKLW-KEKGQIASSSDATGWSLE 369
Cdd:COG5008  321 FRLYEAGKISYEEALRNADSANNLRLRIKLGsEGAAKADLDAGFDGLTLD 370
pilT_fam TIGR01420
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ...
 2-343 2.39e-158

pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]


Pssm-ID: 273613  Cd Length: 343  Bit Score: 448.31  E-value: 2.39e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670    2 ELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLPQIGRF 81
Cdd:TIGR01420   1 SLEEILREAVKLGASDIHLTAGAPPAMRIDGDLVRIEFEPLTPEDTQKLAREILSEKQREEFEENGELDFSFSLPGVGRF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   82 RINIFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIEDP 161
Cdd:TIGR01420  81 RVNAFYQRGGVALVLRLIPSKIPTFEELGLPPVLRELAERPRGLILVTGPTGSGKSTTLASMIDYINKNKAYHIITIEDP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  162 VEFVHRHRKSIINQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRII 241
Cdd:TIGR01420 161 IEYVHTNKRSLINQREVGEDTLSFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTLHTNSAAQTIERII 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  242 NFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDG-GRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSAL 320
Cdd:TIGR01420 241 DVFPAEEQEQIRTQLAESLVAIISQRLLPKADGgGRVLAVEILINTPAVRNLIREGKTHQIKSLIQTGQQLGMQTFDQHL 320

                         330       340
                  ....*....|....*....|...
gi 516376670  321 FDLVVEGVIDEEEAVKNADSANN 343
Cdd:TIGR01420 321 AQLYKKGLITLEDALEAAPSPHE 343
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
 103-324 7.34e-120

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 346.06  E-value: 7.34e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 103 IPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIEDPVEFVHRHRKSIINQREVGVDT 182
Cdd:cd01131    1 IPTFEELGLPPVLKDLALKPRGLVLVTGPTGSGKSTTLAAMIDYINETRSKHIITIEDPIEFVHKHKKSLINQREVGRDT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 183 RSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEERRPQLLNDLGNNLKA 262
Cdd:cd01131   81 ESFAAALRAALREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIIDVFPPEQQEQVRIQLASSLRG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516376670 263 FVSQRLVKTTDG-GRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSALFDLV 324
Cdd:cd01131  161 VISQRLLPKKDGgGRVAAFEILINTPAIRNLIREGKTHQIPSLIQTGARDGMQTMDQSLYELY 223
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
 80-270 5.87e-36

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 132.02  E-value: 5.87e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   80 RFRINIFKQRNEVSLVARNIK--TEIPRFEDLKLPTVLLDTIME----KRGLVLFVGGTGSGKSTSLAALIDHRNRnSGG 153
Cdd:pfam00437  81 RVRVSTLPTAGGEKLVIRLLDpsNVALSLDELGMTGAQDEALLEflrqPRGNILVTGPTGSGKTTTLYAALGELNT-RDE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  154 HIITIEDPVEFVHRHrksiINQreVGVDTR---SFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHA 230
Cdd:pfam00437 160 NIVTVEDPVEIQLEG----INQ--VQLNARagvTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHT 233

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 516376670  231 NNANQALDRIINFFPEErrpqllNDLGNNLKAFVSQRLVK 270
Cdd:pfam00437 234 NSAAGALTRLQDMGVPP------FELASSLLLVIAQRLVR 267
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
70-271 5.48e-35

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 129.49  E-value: 5.48e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  70 NLAIS---LPQIGRFRINIFKQR-------------NEvSLVAR------NIKTEIPRFEDLKLptvLLDTIMEKRGLVL 127
Cdd:NF041000  57 GMDIGekrRPQSGAFTYELNEQQislrlstvgdflgRE-SLVIRllyqleQIKPQLFFPEQFQL---LKQLLQRRSGLIL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 128 FVGGTGSGKSTSLAALIdhRNRNSGGHIITIEDPVEFVHRHrksiINQREV----GVDtrsFHAALKNTLRQAPDVILIG 203
Cdd:NF041000 133 FSGPTGSGKTTTMYSLA--RKLALNKQVITIEDPVEIKEPN----FLQLQVnekaGMT---YDTLLKAALRHRPDILIIG 203

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 516376670 204 EIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEErrpqllNDLGNNLKAFVSQRLVKT 271
Cdd:NF041000 204 EIRDAETAKAAIRAALTGHLVLSTVHAKSAAGVIYRLLELGISK------EELEQTLIGISYQRLIPT 265
PRK10436 PRK10436
hypothetical protein; Provisional
 107-270 2.29e-24

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 103.85  E-value: 2.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 107 EDLKLPTVLLDTIMEK----RGLVLFVGGTGSGKSTSLAALIDHRNRNSGgHIITIEDPVEfvhrhrksI----INQREV 178
Cdd:PRK10436 198 ETLGMTPAQLAQFRQAlqqpQGLILVTGPTGSGKTVTLYSALQTLNTAQI-NICSVEDPVE--------IplagINQTQI 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 179 ----GVDtrsFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRiinffpeerrpqlLN 254
Cdd:PRK10436 269 hpkaGLT---FQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTSETLVR-------------LQ 332

                        170       180
                 ....*....|....*....|...
gi 516376670 255 DLG-------NNLKAFVSQRLVK 270
Cdd:PRK10436 333 QMGiarwmlaSALKLVIAQRLVR 355
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 122-205 7.91e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   122 KRGLVLFVGGTGSGKSTSLAALIDHRNRNSGG-HIITIEDPVEFVHRHRKSIINQREVGVDTR--SFHAALKNTLRQAPD 198
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGvIYIDGEDILEEVLDQLLLIIVGGKKASGSGelRLRLALALARKLKPD 80


                   ....*..
gi 516376670   199 VILIGEI 205
Cdd:smart00382  81 VLILDEI 87
 
Name Accession Description Interval E-value
PilU COG5008
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
1-369 0e+00

Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];


Pssm-ID: 444032  Cd Length: 370  Bit Score: 713.02  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   1 MELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLPQIGR 80
Cdd:COG5008    1 MDLEDLLKLMVEKKASDLFITAGAPPSIKIDGKLTPLSQQPLTPEQVRELAYSIMNEEQREEFERTKECNFAISLPGVGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  81 FRINIFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIED 160
Cdd:COG5008   81 FRVNAFRQRGSVGMVLRRIETEIPTLDELGLPPVLKDLIMEKRGLVLFVGATGSGKSTTLAAMIDHRNENSSGHILTIED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 161 PVEFVHRHRKSIINQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRI 240
Cdd:COG5008  161 PIEFVHKHKKSIVTQREVGVDTESYEVALKNALRQAPDVILIGEIRDRETMEHAIAFAETGHLCLATLHANNANQALDRI 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 241 INFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDGGRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSAL 320
Cdd:COG5008  241 INFFPEERRPQLLMDLSLNLRAIVSQRLVPTKDGGRVAAVEVLLNTPLIADLIRKGEIHEIKEAMEKSRELGMQTFDQAL 320

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 516376670 321 FDLVVEGVIDEEEAVKNADSANNLRLKIKLW-KEKGQIASSSDATGWSLE 369
Cdd:COG5008  321 FRLYEAGKISYEEALRNADSANNLRLRIKLGsEGAAKADLDAGFDGLTLD 370
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
 1-338 3.10e-170

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


Pssm-ID: 442056  Cd Length: 342  Bit Score: 478.43  E-value: 3.10e-170
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   1 MELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLPQIGR 80
Cdd:COG2805    3 MDLDELLKLAVEQGASDLHLTVGSPPMLRIDGELVPLDDPPLTPEDLEALLKEILTEEQRERLEEEGELDFSYSLPGLGR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  81 FRINIFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIED 160
Cdd:COG2805   83 FRVNIFRQRGGVAAVLRLIPSEIPTLEELGLPPVLKELAELPRGLVLVTGPTGSGKSTTLAAMIDYINETRAKHIITIED 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 161 PVEFVHRHRKSIINQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRI 240
Cdd:COG2805  163 PIEFVHKHKKSLINQREVGRDTPSFANALRAALREDPDVILVGEMRDLETIEAALTAAETGHLVFATLHTNSAAQTIDRI 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 241 INFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDGGRR-AAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSA 319
Cdd:COG2805  243 IDVFPPEEQAQIRSQLAESLRGVISQRLLPRADGGGRvAAREILVNTPAVRNLIREGKTHQIPSLIQTGKKLGMQTMDQS 322

                        330
                 ....*....|....*....
gi 516376670 320 LFDLVVEGVIDEEEAVKNA 338
Cdd:COG2805  323 LAELVKEGLITEETALAYA 341
pilT_fam TIGR01420
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ...
 2-343 2.39e-158

pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]


Pssm-ID: 273613  Cd Length: 343  Bit Score: 448.31  E-value: 2.39e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670    2 ELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLPQIGRF 81
Cdd:TIGR01420   1 SLEEILREAVKLGASDIHLTAGAPPAMRIDGDLVRIEFEPLTPEDTQKLAREILSEKQREEFEENGELDFSFSLPGVGRF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   82 RINIFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIEDP 161
Cdd:TIGR01420  81 RVNAFYQRGGVALVLRLIPSKIPTFEELGLPPVLRELAERPRGLILVTGPTGSGKSTTLASMIDYINKNKAYHIITIEDP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  162 VEFVHRHRKSIINQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRII 241
Cdd:TIGR01420 161 IEYVHTNKRSLINQREVGEDTLSFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTLHTNSAAQTIERII 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  242 NFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDG-GRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSAL 320
Cdd:TIGR01420 241 DVFPAEEQEQIRTQLAESLVAIISQRLLPKADGgGRVLAVEILINTPAVRNLIREGKTHQIKSLIQTGQQLGMQTFDQHL 320

                         330       340
                  ....*....|....*....|...
gi 516376670  321 FDLVVEGVIDEEEAVKNADSANN 343
Cdd:TIGR01420 321 AQLYKKGLITLEDALEAAPSPHE 343
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
 103-324 7.34e-120

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 346.06  E-value: 7.34e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 103 IPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNSGGHIITIEDPVEFVHRHRKSIINQREVGVDT 182
Cdd:cd01131    1 IPTFEELGLPPVLKDLALKPRGLVLVTGPTGSGKSTTLAAMIDYINETRSKHIITIEDPIEFVHKHKKSLINQREVGRDT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 183 RSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEERRPQLLNDLGNNLKA 262
Cdd:cd01131   81 ESFAAALRAALREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIIDVFPPEQQEQVRIQLASSLRG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516376670 263 FVSQRLVKTTDG-GRRAAVEIMLGTHTIRDMVKRGEFGGLKEVMEKSKALGMVTFDSALFDLV 324
Cdd:cd01131  161 VISQRLLPKKDGgGRVAAFEILINTPAIRNLIREGKTHQIPSLIQTGARDGMQTMDQSLYELY 223
DotB_TraJ cd19516
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ...
 115-281 1.73e-50

dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.


Pssm-ID: 410924 [Multi-domain]  Cd Length: 179  Bit Score: 167.17  E-value: 1.73e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 115 LLDTIMEKRGLVLFVGGTGSGKSTSLAALIDH--RNRNSGGHIITIEDPVEFVHR--HRK-SIINQREVGVDTRSFHAAL 189
Cdd:cd19516    3 LVEALFPREGLVYVAGATGSGKSTLLAAIYRYilENDPPDRKIITYEDPIEFVYDgiKSKhSIIVQSQIPRHFKSFAKAV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 190 KNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEERRPQLLNDLGNNLKAFVSQRLV 269
Cdd:cd19516   83 REALRRKPSLIGVGELRDQETISAAVEASLTGHPVYSTVHTKSVAETIRRLISLFPPEERDAAAYDLLSTLRFIIVQRLV 162

                        170
                 ....*....|..
gi 516376670 270 KTTDGGRRAAVE 281
Cdd:cd19516  163 RTTDGKRVAVRE 174
plasmid_TraJ TIGR02525
plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated ...
 2-334 3.65e-50

plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated with plasmid transfer loci in bacteria. This family is most similar to the DotB ATPase of a type-IV secretion-like system of obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii (TIGR02524). [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 131577 [Multi-domain]  Cd Length: 372  Bit Score: 172.30  E-value: 3.65e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670    2 ELRDMLQILAKQDGSDLYLSTGAPPCAKFNGGLRPLSETPLEPGEVASIADAIMDGEQKQQFEKELEMNLAISLP----- 76
Cdd:TIGR02525  11 TLRRFFVHCSRHEVSDIHLQGGSPIVVERHGRQVPASSFPLDNLELERLVDEVFGPEIKPTVKSGAPVDRAIQLRgdeng 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   77 QIG-------RFRIN-----IFKQRNEVSLVARNIKTEIPRFEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALI 144
Cdd:TIGR02525  91 RYGlgrgervRFRCNfiqatIGKLETAISLTLRVIPSDIPDLKQMGIEPDLFNSLLPAAGLGLICGETGSGKSTLAASIY 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  145 DH-RNRNSGGHIITIEDPVEFVHRHRKSII--NQREVGVDTRSFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETG 221
Cdd:TIGR02525 171 QHcGETYPDRKIVTYEDPIEYILGSPDDLLppAQSQIGRDVDSFANGIRLALRRAPKIIGVGEIRDLETFQAAVLAGQSG 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  222 HLAISTLHANNANQALDRIINFFPEERRPQLLNDLGNNLKAFVSQRLVKTTDGGRRAAVEIMLGTHTIRDMVKRGEFGGL 301
Cdd:TIGR02525 251 HFCLGTLHVKSPGEAISRCLQMYPPEMREAAAFDLLSILQYIIVQRLLRTTDGKRQAVREYIVFDDSLRRKLYDVDYSKW 330

                         330       340       350
                  ....*....|....*....|....*....|...
gi 516376670  302 KEVMEKSKALGMVTFDSALFDLVVEGVIDEEEA 334
Cdd:TIGR02525 331 GRYIDDILRAEQRRIADQAWAMHQEGRIDEREA 363
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
 123-286 1.82e-49

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 163.81  E-value: 1.82e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 123 RGLVLFVGGTGSGKSTSLAALIDHRNRNsGGHIITIEDPVEFVHrhrkSIINQREVGVDT-RSFHAALKNTLRQAPDVIL 201
Cdd:cd01129   11 HGLILVTGPTGSGKTTTLYAMLRELNGP-ERNIITIEDPVEYQI----PGINQSQVNEKIgLTFADALRAILRQDPDIIM 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 202 IGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEErrpqllNDLGNNLKAFVSQRLVkttdgGRRAAVE 281
Cdd:cd01129   86 VGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEP------FLLASALRGVIAQRLV-----GRTAIAE 154


                 ....*
gi 516376670 282 IMLGT 286
Cdd:cd01129  155 VLVLD 159
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
 70-336 1.16e-43

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 159.20  E-value: 1.16e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  70 NLAIS---LPQIGRFRINIfkQRNEV-------------SLVAR--NIKTEIPRFEDLKLPTVLLDTIME--KR--GLVL 127
Cdd:COG2804  240 NLDIAerrLPQDGRIKLRL--GGREIdlrvstlptvygeKVVLRilDKSAALLDLEQLGFSPDQLERLRRliRRphGIIL 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 128 FVGGTGSGKSTSLAALIDHRN---RNsgghIITIEDPVEFVHRHrksiINQ----REVGVDtrsFHAALKNTLRQAPDVI 200
Cdd:COG2804  318 VTGPTGSGKTTTLYAALNELNtpeRN----IITVEDPVEYQLPG----INQvqvnPKIGLT---FASALRSILRQDPDVI 386

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 201 LIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEerrPQLLNDlgnNLKAFVSQRLVKT--------- 271
Cdd:COG2804  387 MVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVE---PFLLAS---SLLGVLAQRLVRRlcphckepy 460

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 272 ----------------TDG------------------GRRAAVEIMLGTHTIRDMVKRGefGGLKEVMEKSKALGMVT-F 316
Cdd:COG2804  461 epdpeelerlglppeeLAPltfyrgvgcehcngtgykGRTGIYELLVIDDELRELIAEG--ASAAELREAARKEGMRTlR 538

                        330       340
                 ....*....|....*....|
gi 516376670 317 DSALfDLVVEGVIDEEEAVK 336
Cdd:COG2804  539 EDGL-EKVLQGITTLEEVLR 557
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
 80-270 5.87e-36

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 132.02  E-value: 5.87e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   80 RFRINIFKQRNEVSLVARNIK--TEIPRFEDLKLPTVLLDTIME----KRGLVLFVGGTGSGKSTSLAALIDHRNRnSGG 153
Cdd:pfam00437  81 RVRVSTLPTAGGEKLVIRLLDpsNVALSLDELGMTGAQDEALLEflrqPRGNILVTGPTGSGKTTTLYAALGELNT-RDE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  154 HIITIEDPVEFVHRHrksiINQreVGVDTR---SFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHA 230
Cdd:pfam00437 160 NIVTVEDPVEIQLEG----INQ--VQLNARagvTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHT 233

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 516376670  231 NNANQALDRIINFFPEErrpqllNDLGNNLKAFVSQRLVK 270
Cdd:pfam00437 234 NSAAGALTRLQDMGVPP------FELASSLLLVIAQRLVR 267
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
70-271 5.48e-35

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 129.49  E-value: 5.48e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  70 NLAIS---LPQIGRFRINIFKQR-------------NEvSLVAR------NIKTEIPRFEDLKLptvLLDTIMEKRGLVL 127
Cdd:NF041000  57 GMDIGekrRPQSGAFTYELNEQQislrlstvgdflgRE-SLVIRllyqleQIKPQLFFPEQFQL---LKQLLQRRSGLIL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 128 FVGGTGSGKSTSLAALIdhRNRNSGGHIITIEDPVEFVHRHrksiINQREV----GVDtrsFHAALKNTLRQAPDVILIG 203
Cdd:NF041000 133 FSGPTGSGKTTTMYSLA--RKLALNKQVITIEDPVEIKEPN----FLQLQVnekaGMT---YDTLLKAALRHRPDILIIG 203

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 516376670 204 EIRDRETMEHALAFSETGHLAISTLHANNANQALDRIINFFPEErrpqllNDLGNNLKAFVSQRLVKT 271
Cdd:NF041000 204 EIRDAETAKAAIRAALTGHLVLSTVHAKSAAGVIYRLLELGISK------EELEQTLIGISYQRLIPT 265
PRK10436 PRK10436
hypothetical protein; Provisional
 107-270 2.29e-24

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 103.85  E-value: 2.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 107 EDLKLPTVLLDTIMEK----RGLVLFVGGTGSGKSTSLAALIDHRNRNSGgHIITIEDPVEfvhrhrksI----INQREV 178
Cdd:PRK10436 198 ETLGMTPAQLAQFRQAlqqpQGLILVTGPTGSGKTVTLYSALQTLNTAQI-NICSVEDPVE--------IplagINQTQI 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 179 ----GVDtrsFHAALKNTLRQAPDVILIGEIRDRETMEHALAFSETGHLAISTLHANNANQALDRiinffpeerrpqlLN 254
Cdd:PRK10436 269 hpkaGLT---FQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTSETLVR-------------LQ 332

                        170       180
                 ....*....|....*....|...
gi 516376670 255 DLG-------NNLKAFVSQRLVK 270
Cdd:PRK10436 333 QMGiarwmlaSALKLVIAQRLVR 355
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
 115-242 1.09e-22

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 93.76  E-value: 1.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 115 LLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNsgGHIITIEDPVEfVHRHRKSII-------NQREVGVDTRSfha 187
Cdd:cd01130    4 FLRLAVRARKNILISGGTGSGKTTLLNALLSFIPPD--ERIVTIEDTRE-LQLPHPNVVhlltrpgGGEKGEVTMAD--- 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516376670 188 ALKNTLRQAPDVILIGEIRDRETME--HALAfseTGHL-AISTLHANNANQALDRIIN 242
Cdd:cd01130   78 LLKAALRMRPDRIIVGEVRGGEAYDmlQAMN---TGHPgSITTIHANSAEDAIDRLAT 132
type_II_IV_secretion_ATPases cd19477
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ...
 124-273 1.33e-21

type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410885 [Multi-domain]  Cd Length: 168  Bit Score: 90.53  E-value: 1.33e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 124 GLVLFVGGTGSGKSTSLAALIDHRNRNSggHIITIEDPVEFVHRHRKSIiNQREVGVDTrSFHAALKNTLRQAPDVILIG 203
Cdd:cd19477   11 KNVIVCGGTGSGKTTYIKSILEFIPKEE--RIISIEDTEEIVFKHHKNY-TQLFFGGNI-TSADCLKSCLRQRPDRIILG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 204 EIRDrETMEHALAFSETGH-LAISTLHANNANQALDRIINF---------FPEERRPQLLNDLgnnLKAFVSQRLVKTTD 273
Cdd:cd19477   87 ELRS-SEAYDFYNVLCSGHkGTLTTLHAGSSEEAFIRLAN*sssnsaarnIKFESLIEGFKDL---IDGIVHINHHKQCD 162
VirB11 COG0630
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ...
 115-283 3.08e-21

Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440395 [Multi-domain]  Cd Length: 462  Bit Score: 94.76  E-value: 3.08e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 115 LLDTIMEKRGLVLFVGGTGSGKSTSLAAL---IDHRNRnsgghIITIEDPVEFVHRHRKSIinqREVgvdTR-SFHAA-- 188
Cdd:COG0630  282 YLWLLLENGKSVLVAGGTASGKTTLLNALlsfIPPDAK-----IVTIEDTRELNLPHENWI---SLV---TReSFGGEeg 350

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 189 -------LKNTLRQAPDVILIGEIRDRE--TMEHALAfseTGHLAISTLHANNANQALDRIINffPEERRPQLLNDlgnN 259
Cdd:COG0630  351 dvtmfdlLKAALRQRPDYIVVGEVRGEEayTLFQAMA---TGHGVLSTFHADSVESAINRLTS--PPINVPRTLLQ---A 422

                        170       180
                 ....*....|....*....|....
gi 516376670 260 LKAFVSQRLVKTTDGGRRAAVEIM 283
Cdd:COG0630  423 LDLVVFQKRVRVGGKRVRRVTSIV 446
VirB11 TIGR02788
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ...
 119-283 1.25e-16

P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.


Pssm-ID: 274301  Cd Length: 308  Bit Score: 79.70  E-value: 1.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  119 IMEKRGLVLFvGGTGSGKSTSLAALIDHRNRNSggHIITIEDPVEFVHRHrKSIINQREVGVDTRSFH----AALKNTLR 194
Cdd:TIGR02788 141 IASRKNIIIS-GGTGSGKTTFLKSLVDEIPKDE--RIITIEDTREIFLPH-PNYVHLFYSKGGQGLAKvtpkDLLQSCLR 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  195 QAPDVILIGEIRDRETMEHALAFSeTGHL-AISTLHANNANQALDRIINFFpeerrpqLLNDLGNNLKAFVSQRLVKTT- 272
Cdd:TIGR02788 217 MRPDRIILGELRGDEAFDFIRAVN-TGHPgSITTLHAGSPEEAFEQLALMV-------KSSQAGLGLDFAYIVKLVREVi 288

                         170
                  ....*....|....*....
gi 516376670  273 --------DGGRRAAVEIM 283
Cdd:TIGR02788 289 divvqinrRGGGRKITEVY 307
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 115-242 1.01e-15

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 77.90  E-value: 1.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 115 LLDTIMEKRGLVLFVGGTGSGKSTSLAAL---IDHRNRnsgghIITIEDPVE--FVHRH-------RKSIINQREVgvdt 182
Cdd:COG4962  174 FLRAAVRARLNILVSGGTGSGKTTLLNALsgfIPPDER-----IVTIEDAAElqLQHPHvvrletrPPNVEGAGEV---- 244

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516376670 183 rSFHAALKNTLRQAPDVILIGEIRDRE--TMEHALafsETGHL-AISTLHANNANQALDRIIN 242
Cdd:COG4962  245 -TLRDLVRNALRMRPDRIIVGEVRGAEalDMLQAM---NTGHDgSMSTLHANSARDALARLET 303
PRK13894 PRK13894
conjugal transfer ATPase TrbB; Provisional
 114-240 1.82e-13

conjugal transfer ATPase TrbB; Provisional


Pssm-ID: 184377  Cd Length: 319  Bit Score: 70.54  E-value: 1.82e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 114 VLLDTIMEKRGlVLFVGGTGSGKSTSLAALIDHR-NRNSGGHIITIEDPVE-------FVHRHrKSIinqrEVgvdtrSF 185
Cdd:PRK13894 140 AIIAAVRAHRN-ILVIGGTGSGKTTLVNAIINEMvIQDPTERVFIIEDTGEiqcaaenYVQYH-TSI----DV-----NM 208

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 516376670 186 HAALKNTLRQAPDVILIGEIRDRETMEHALAFSeTGHL-AISTLHANNANQALDRI 240
Cdd:PRK13894 209 TALLKTTLRMRPDRILVGEVRGPEALDLLMAWN-TGHEgGAATLHANNAKAGLDRL 263
PRK13851 PRK13851
type IV secretion system protein VirB11; Provisional
 123-240 1.37e-09

type IV secretion system protein VirB11; Provisional


Pssm-ID: 172375  Cd Length: 344  Bit Score: 59.14  E-value: 1.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 123 RGLVLFVGGTGSGKSTSLAALIDHRNRNSggHIITIEDPVEFV---HRHRKSIINQREVGVDTRSFHAALKNTLRQAPDV 199
Cdd:PRK13851 162 RLTMLLCGPTGSGKTTMSKTLISAIPPQE--RLITIEDTLELViphENHVRLLYSKNGAGLGAVTAEHLLQASLRMRPDR 239

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 516376670 200 ILIGEIRDretmEHALAF-SE--TGHL-AISTLHANNANQALDRI 240
Cdd:PRK13851 240 ILLGEMRD----DAAWAYlSEvvSGHPgSISTIHGANPVQGFKKL 280
PRK13833 PRK13833
conjugal transfer protein TrbB; Provisional
 130-277 2.89e-08

conjugal transfer protein TrbB; Provisional


Pssm-ID: 172360 [Multi-domain]  Cd Length: 323  Bit Score: 54.80  E-value: 2.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 130 GGTGSGKSTSLAALIDHRNRNSGGHIITI-EDPVEFVHRHRKSIINQREvgvDTRSFHAALKNTLRQAPDVILIGEIRDR 208
Cdd:PRK13833 151 GGTGSGKTTLANAVIAEIVASAPEDRLVIlEDTAEIQCAAENAVALHTS---DTVDMARLLKSTMRLRPDRIIVGEVRDG 227

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 209 ETMEHALAFSeTGHL-AISTLHANNANQALDRIINFFPEERRPQLLNDLGNNLKAFVSqrlVKTTDGGRR 277
Cdd:PRK13833 228 AALTLLKAWN-TGHPgGVTTIHSNTAMSALRRLEQLTAEASQQPMQEVIGEAVDLIVS---IERTGKGRR 293
PRK13900 PRK13900
type IV secretion system ATPase VirB11; Provisional
 119-284 2.70e-07

type IV secretion system ATPase VirB11; Provisional


Pssm-ID: 184381  Cd Length: 332  Bit Score: 51.68  E-value: 2.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 119 IMEKRGLVLfVGGTGSGKST-SLAAL--IDHRNRnsgghIITIEDPVEFV---HRHRKSII----NQREVGVDTRSFHAA 188
Cdd:PRK13900 157 VISKKNIII-SGGTSTGKTTfTNAALreIPAIER-----LITVEDAREIVlsnHPNRVHLLaskgGQGRAKVTTQDLIEA 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670 189 lknTLRQAPDVILIGEIRDREtmehalAFS-----ETGHL-AISTLHANNANQALDRI--------INFFPEERRPQLLn 254
Cdd:PRK13900 231 ---CLRLRPDRIIVGELRGAE------AFSflraiNTGHPgSISTLHADSPAMAIEQLklmvmqagLGMPPDQIKKYIL- 300

                        170       180       190
                 ....*....|....*....|....*....|
gi 516376670 255 dlgnNLKAFVSQrlVKTTDGGRRAAVEIML 284
Cdd:PRK13900 301 ----NVVDIVVQ--LKRGSGGKRYVSEIYF 324
PRK13764 PRK13764
ATPase; Provisional
 18-161 1.84e-06

ATPase; Provisional


Pssm-ID: 184311 [Multi-domain]  Cd Length: 602  Bit Score: 49.84  E-value: 1.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670  18 LYLSTGAPPCAKfNGG-----LRPLSETPLEPGEVASIADAIMDgEQKQQFEK--ELEMNLAISLpQIGRFRINI----F 86
Cdd:PRK13764 147 VHLKEGVPPMAK-KGKpgewkLVKIRDEPLTEEELEEIAREILE-RAKRDPDGfiEIERRGATVV-QLGNYRIVIarppF 223

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516376670  87 KQRNEVSLVARNIKTEIprfEDLKLPTVLLDTIMEKRGLVLFVGGTGSGKSTSLAALIDHRNRNsgGHII-TIEDP 161
Cdd:PRK13764 224 SDGIEITAVRPVVKLSL---EDYNLSEKLKERLEERAEGILIAGAPGAGKSTFAQALAEFYADM--GKIVkTMESP 294
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 122-205 7.91e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   122 KRGLVLFVGGTGSGKSTSLAALIDHRNRNSGG-HIITIEDPVEFVHRHRKSIINQREVGVDTR--SFHAALKNTLRQAPD 198
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGvIYIDGEDILEEVLDQLLLIIVGGKKASGSGelRLRLALALARKLKPD 80


                   ....*..
gi 516376670   199 VILIGEI 205
Cdd:smart00382  81 VLILDEI 87
FlhF TIGR03499
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility]
 63-158 1.11e-03

flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274609 [Multi-domain]  Cd Length: 282  Bit Score: 40.40  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516376670   63 FEKELEMNLAISLPQIGRFRINifkQRNEVSLVARNIKTEIPRfedlklptvllDTIMEKRGLVLFVGGTGSGKSTSLA- 141
Cdd:TIGR03499 148 VSEELARELLEKLPEDADAEDA---WRWLREALEGMLPVKPEE-----------DPILEQGGVIALVGPTGVGKTTTLAk 213

                          90       100
                  ....*....|....*....|.
gi 516376670  142 ----ALIDHRNRNSGghIITI 158
Cdd:TIGR03499 214 laarFALEHGKKKVA--LITT 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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