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Conserved domains on  [gi|516238986|ref|WP_017642949|]
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MULTISPECIES: iron ABC transporter permease [Pseudomonadaceae]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 35-341 1.03e-90

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 273.48  E-value: 1.03e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  35 FGEMPIAPLTSLQAIANglglgpYPVERIVQGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGAS 114
Cdd:COG0609    4 LGAVPISLSDVLRALLG------PDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 115 TGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVVL---PFLGSGGSTRIILAGVAASQLFNALTAYIVATAaNAEQARSVM 191
Cdd:COG0609   78 LGAVLAIVLGGGLSALGLPLAAFLGALLAALLVYllaRRGGGLSPLRLVLAGVAVSALFSALTSLLLLLA-DPEQLRSIV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 192 FWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGF 271
Cdd:COG0609  157 FWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGF 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 272 VGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:COG0609  237 VGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 35-341 1.03e-90

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 273.48  E-value: 1.03e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  35 FGEMPIAPLTSLQAIANglglgpYPVERIVQGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGAS 114
Cdd:COG0609    4 LGAVPISLSDVLRALLG------PDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 115 TGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVVL---PFLGSGGSTRIILAGVAASQLFNALTAYIVATAaNAEQARSVM 191
Cdd:COG0609   78 LGAVLAIVLGGGLSALGLPLAAFLGALLAALLVYllaRRGGGLSPLRLVLAGVAVSALFSALTSLLLLLA-DPEQLRSIV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 192 FWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGF 271
Cdd:COG0609  157 FWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGF 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 272 VGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:COG0609  237 VGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 67-339 9.12e-68

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 215.08  E-value: 9.12e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986   67 IVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAV 146
Cdd:pfam01032  37 IVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAILLGGSLSLFALPLAAFIGALLAALL 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  147 VLPFLGSGG---STRIILAGVAASQLFNALTAYIVATAaNAEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLAC 223
Cdd:pfam01032 117 VYFLSRGRGgasPLRLILAGIAVSALLSALTSLLLLLL-NPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLL 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  224 ARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFM 303
Cdd:pfam01032 196 ARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLL 275

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 516238986  304 VLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYR 339
Cdd:pfam01032 276 LLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
68-341 2.08e-51

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 180.81  E-value: 2.08e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  68 VWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVV 147
Cdd:PRK10577 393 LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALI 472

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 148 LPFLGSGG--STRIILAGVAASQLFNALTAYIVATAAnaEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACAR 225
Cdd:PRK10577 473 LLLARRGGfaPERLLLTGIALSALFTALIQLLLASGD--PRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRR 550

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 226 ALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFMVL 305
Cdd:PRK10577 551 WLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVL 630

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 516238986 306 ADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:PRK10577 631 ADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSR 666
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 77-337 7.66e-47

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 159.26  E-value: 7.66e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  77 LVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVVLPFLGSGGS 156
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 157 T--RIILAGVAASQLFNALTAYIVATAANAEQarSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGE 234
Cdd:cd06550   82 SpsKLILIGIVLSAFFSAGVILISLLSDDSLQ--DLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 235 DAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIVARTLV 314
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 516238986 315 AKQtLPIGVVTALVGAPAFAFIL 337
Cdd:cd06550  240 PSE-LPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 35-341 1.03e-90

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 273.48  E-value: 1.03e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  35 FGEMPIAPLTSLQAIANglglgpYPVERIVQGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGAS 114
Cdd:COG0609    4 LGAVPISLSDVLRALLG------PDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 115 TGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVVL---PFLGSGGSTRIILAGVAASQLFNALTAYIVATAaNAEQARSVM 191
Cdd:COG0609   78 LGAVLAIVLGGGLSALGLPLAAFLGALLAALLVYllaRRGGGLSPLRLVLAGVAVSALFSALTSLLLLLA-DPEQLRSIV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 192 FWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGF 271
Cdd:COG0609  157 FWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGF 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 272 VGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:COG0609  237 VGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 67-339 9.12e-68

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 215.08  E-value: 9.12e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986   67 IVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAV 146
Cdd:pfam01032  37 IVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAILLGGSLSLFALPLAAFIGALLAALL 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  147 VLPFLGSGG---STRIILAGVAASQLFNALTAYIVATAaNAEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLAC 223
Cdd:pfam01032 117 VYFLSRGRGgasPLRLILAGIAVSALLSALTSLLLLLL-NPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLL 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  224 ARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFM 303
Cdd:pfam01032 196 ARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLL 275

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 516238986  304 VLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYR 339
Cdd:pfam01032 276 LLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 65-344 2.10e-56

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 186.21  E-value: 2.10e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  65 QGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTG-AVLVMLLGVGGGVLGVSLGAFLGAVLA 143
Cdd:COG4139   48 QLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGlVLVVLLGGGLLPPWLLSLAAIAGALLV 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 144 FAVVLPFLGSGGST-RIILAGVAASQLFNALTAYIVaTAANAEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLA 222
Cdd:COG4139  128 TLLLLAFARRRLSNaRLLLIGVALGIICSAIMTWAV-YFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPVLLWLCLQ 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 223 cARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALF 302
Cdd:COG4139  207 -GKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAAL 285

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 516238986 303 MVLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAREVR 344
Cdd:COG4139  286 LLLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRRRKIR 327
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
68-341 2.08e-51

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 180.81  E-value: 2.08e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  68 VWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVV 147
Cdd:PRK10577 393 LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALI 472

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 148 LPFLGSGG--STRIILAGVAASQLFNALTAYIVATAAnaEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACAR 225
Cdd:PRK10577 473 LLLARRGGfaPERLLLTGIALSALFTALIQLLLASGD--PRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRR 550

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 226 ALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFMVL 305
Cdd:PRK10577 551 WLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVL 630

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 516238986 306 ADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:PRK10577 631 ADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSR 666
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 65-344 5.61e-51

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 172.45  E-value: 5.61e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  65 QGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVL-GVSLGAFLGAVLA 143
Cdd:PRK03784  51 ELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPwALSLCAIAGALLI 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 144 FAVVLPFLGSG--GSTRIILAGVAASQLFNALTAYIVATAANAEqARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCL 221
Cdd:PRK03784 131 TLILLRFARRHrlSTSRLLLAGVALGIICSALMTWAVYFSTSLD-LRQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLCC 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 222 aCARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGAL 301
Cdd:PRK03784 210 -QGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAS 288

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 516238986 302 FMVLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAREVR 344
Cdd:PRK03784 289 LLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRAR 331
btuC PRK09535
cobalamin ABC transporter permease BtuC;
58-344 8.43e-51

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 173.01  E-value: 8.43e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  58 YPVERIVQGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLgAF 137
Cdd:PRK09535  81 FAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFGLQAA-AF 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 138 LGAVLAFAVVLPFLGSGGST---RIILAGVAASQLFNALTAYIVATAAnaEQARSVMFWLLGSLAGVRWPDVWLAAGVVL 214
Cdd:PRK09535 160 AGALVAAFGVYAIATENGRTpvaTLLLAGVAVQTFLGAVISYLLLHSG--ESLRRAVYWLMGHLHGSTWSDVEVALPVVV 237

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 215 AGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPT 294
Cdd:PRK09535 238 VGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPT 317

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 516238986 295 CALIGALFMVLADIVARTLVAKqtLPIGVVTALVGAPAFAFILyRAREVR 344
Cdd:PRK09535 318 SALAGASFLVATDTVARSGPAE--VPVGIVTAALGAPFFLYLL-RTREVH 364
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
39-341 4.28e-47

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 161.79  E-value: 4.28e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  39 PIAPLTSLQAIANGLGLGpypverIVQGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTG-A 117
Cdd:PRK11228  24 PISAADALNALLPGHTPT------LPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAmA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 118 VLVMLLGVGGGVLGVSLGAFLGAVLAFAVVlpFLGSGG------STRIILAGVAASQLFNALTAYIVATAAnaEQARSVM 191
Cdd:PRK11228  98 LTSALSPTPFAGYSLAFIAACGGGLSWLLV--MTAGGGwrhthdRNRLILAGIALSALCMALTRITLLLAE--DHAYGIF 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 192 FWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGF 271
Cdd:PRK11228 174 YWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAF 253

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 272 VGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIVARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:PRK11228 254 IGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARRRG 323
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 77-337 7.66e-47

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 159.26  E-value: 7.66e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  77 LVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVVLPFLGSGGS 156
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 157 T--RIILAGVAASQLFNALTAYIVATAANAEQarSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGE 234
Cdd:cd06550   82 SpsKLILIGIVLSAFFSAGVILISLLSDDSLQ--DLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 235 DAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIVARTLV 314
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 516238986 315 AKQtLPIGVVTALVGAPAFAFIL 337
Cdd:cd06550  240 PSE-LPVGPVTALLGAPYFLYLL 261
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
70-341 4.90e-45

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 156.36  E-value: 4.90e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  70 EYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAVVLP 149
Cdd:PRK09777  49 EYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASLASVGALLLFPSLPVMWLPLLAFIGGMAGLILLKM 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 150 FLGSGGSTRIILAGVAASQLFNALTAYIVATaaNAEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDA 229
Cdd:PRK09777 129 LAGTHQPMKLALTGVALSALWASLTDYLMLS--RPQDINNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDL 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 230 FAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFMVLADIV 309
Cdd:PRK09777 207 LALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLL 286

                        250       260       270
                 ....*....|....*....|....*....|..
gi 516238986 310 ARTLVAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:PRK09777 287 ARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
67-341 8.22e-43

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 156.92  E-value: 8.22e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  67 IVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAFAV 146
Cdd:PRK10577  57 LLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAFAGGLLAAAL 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 147 VLPFLGSGGST--RIILAGVAASQLFNALTAYIVAtaANAEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACA 224
Cdd:PRK10577 137 VFALAGGKRLSplRLVLAGMVVSLYLGALTTLLLL--FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLA 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 225 RALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGALFMV 304
Cdd:PRK10577 215 RPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLL 294

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 516238986 305 LADIVARTL--VAKQTLPIGVVTALVGAPAFAFILYRAR 341
Cdd:PRK10577 295 LTDQLVRLLagVGGELLPTGAVTALIGAPLLLWLLPRLR 333
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
42-329 3.23e-31

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 120.20  E-value: 3.23e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  42 PLTSLQAIANGLGLGPypveRIVQGIVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVM 121
Cdd:PRK10440  33 TLETSQVFAALMGDAP----RSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAM 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 122 LLGVGGGVLGVSLGAFLGAVLAFAVVLPFLGSGGST-RIILAGVAASQLFNALTAYIVATAAnAEQARSVMFWLLGSLAG 200
Cdd:PRK10440 109 VLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTfRLIIIGIGVRAMLVAFNTWLLLKAS-LETALTAGLWNAGSLNG 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 201 VRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVA 280
Cdd:PRK10440 188 LTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIA 267

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 516238986 281 RFLVGPGHGRLLpTCALIGALFMVLADIVARTLVAKQTLPIGVVTALVG 329
Cdd:PRK10440 268 RRLSGTARWGLT-QAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLG 315
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
67-341 5.70e-30

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 116.73  E-value: 5.70e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  67 IVWEYRLSRALVAACCGAGLAVSGAILQALLRNALAEPYVLGLSAGASTGAVLVMLLGVGGGVLGVSLGAFLGAVLAfAV 146
Cdd:PRK10441  55 IVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVA-SL 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 147 VLPFLGSGGST-----RIILAGVAASQLFNALTAYIvaTAANAEQARSVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCL 221
Cdd:PRK10441 134 IVAFTGSQGGGqlspvRLTLAGVALAAVLEGLTSGI--ALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATAL 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 222 ACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVGLVIPHVARFLVGPGHGRLLPTCALIGAL 301
Cdd:PRK10441 212 LLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPA 291

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 516238986 302 FMVLADIVARTLVAKQtLPIGVVTALVGAPAFAFILYRAR 341
Cdd:PRK10441 292 LLLFADIIGRLLVPGE-LRVSVVSAFIGAPVLIFLVRRKT 330
ZnuB COG1108
ABC-type Mn2+/Zn2+ transport system, permease component [Inorganic ion transport and ...
 194-305 5.52e-06

ABC-type Mn2+/Zn2+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440725  Cd Length: 260  Bit Score: 46.96  E-value: 5.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986 194 LLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGAVGFVG 273
Cdd:COG1108  114 LFGSILAVSRSDLLLLAVLAAVVLLLLLLFYRELLLVSFDPELARASGLPVRLLHLLLLVLLALTVVAALQAVGALLVSA 193

                         90       100       110
                 ....*....|....*....|....*....|...
gi 516238986 274 L-VIPHVARFLVGPGHGRLLPTCALIGALFMVL 305
Cdd:COG1108  194 LlIIPAATARLLTRSLRRMLLLAVLIGVLSSVL 226
ABC-3 pfam00950
ABC 3 transport family;
189-305 2.05e-03

ABC 3 transport family;


Pssm-ID: 334323  Cd Length: 258  Bit Score: 39.14  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516238986  189 SVMFWLLGSLAGVRWPDVWLAAGVVLAGLLVCLACARALDAFAFGEDAAASLGVAVGPLRLLLLAVTGLITACLVSLVGA 268
Cdd:pfam00950 110 DLDSYLFGNILTISQQDLIQIAIITAVILILLLLFWKELLLITFDPDHAKVIGLPVQFLYLLLLALIALTIVVALQAVGA 189

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 516238986  269 VGFVG-LVIPHVARFLVGPGHGRLLPTCALIGALFMVL 305
Cdd:pfam00950 190 ILVIAlLIIPAATARRLTRSFDSMLIIAILIGMVSCVA 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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