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Conserved domains on  [gi|515952199|ref|WP_017382782|]
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MULTISPECIES: recombination regulator RecX [Enterobacteriaceae]

Protein Classification

regulatory protein RecX( domain architecture ID 10011252)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
3-166 1.97e-57

recombination regulator RecX; Reviewed


:

Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 176.62  E-value: 1.97e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   3 EPTSRRPAYSRLLDRAVRILAVRDHSEQELRRKLSAPvmskngpediDATAEDYDRVVAWCYEHHYLDDGRFAARFLASR 82
Cdd:PRK00117   2 EDTARRRMYASARARALRLLARREHSRAELRRKLAAK----------GFSEEVIEAVLDRLKEEGLLDDERFAESFVRSR 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199  83 GRKGYGPARIRQELNQKGVARESIEKAMRESEIDWCELAREQAVRKYGEPLPREFSEKVKIQRFLLYRGFLMEDIQDIWR 162
Cdd:PRK00117  72 ARKGYGPRRIRQELRQKGVDREIIEEALAELDIDWEELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLR 151

                 ....
gi 515952199 163 NFTD 166
Cdd:PRK00117 152 NALD 155
 
Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
3-166 1.97e-57

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 176.62  E-value: 1.97e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   3 EPTSRRPAYSRLLDRAVRILAVRDHSEQELRRKLSAPvmskngpediDATAEDYDRVVAWCYEHHYLDDGRFAARFLASR 82
Cdd:PRK00117   2 EDTARRRMYASARARALRLLARREHSRAELRRKLAAK----------GFSEEVIEAVLDRLKEEGLLDDERFAESFVRSR 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199  83 GRKGYGPARIRQELNQKGVARESIEKAMRESEIDWCELAREQAVRKYGEPLPREFSEKVKIQRFLLYRGFLMEDIQDIWR 162
Cdd:PRK00117  72 ARKGYGPRRIRQELRQKGVDREIIEEALAELDIDWEELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLR 151

                 ....
gi 515952199 163 NFTD 166
Cdd:PRK00117 152 NALD 155
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
7-166 6.21e-41

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 134.53  E-value: 6.21e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   7 RRPAYSRLLDRAVRILAVRDHSEQELRRKLSAPVMSkngPEDIDAtaedydrVVAWCYEHHYLDDGRFAARFLASR-GRK 85
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFD---EEEIEE-------VLDRLKEEGYLDDERFAESYVRSRlRRK 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199  86 GYGPARIRQELNQKGVARESIEKAMRE-SEIDWCELAREQAVRKYGEPLPRE-FSEKVKIQRFLLYRGFLMEDIQDIWRN 163
Cdd:COG2137   71 GYGPRRIRQELRQKGIDEELIEEALEElDEEDELEAARELARKKFGSLKPLDpAKEKQKLARFLARRGFSSDLIRRVLRE 150

                 ...
gi 515952199 164 FTD 166
Cdd:COG2137  151 LLE 153
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
50-163 2.26e-28

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 101.51  E-value: 2.26e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   50 DATAEDYDRVVAWCYEHHYLDDGRFAARFLASRGR-KGYGPARIRQELNQKGVARESIEKAMreSEIDWCEL-AREQAVR 127
Cdd:pfam02631   5 GFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARtRGKGPRRIRQELRQKGVDEEIIEEAL--EEFDEEEQiARELAEK 82
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 515952199  128 KYGEPLPR-EFSEKVKIQRFLLYRGFLMEDIQDIWRN 163
Cdd:pfam02631  83 KFKRYPAEsDRKLKQKLIRFLARRGFSSEVIRAALQE 119
 
Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
3-166 1.97e-57

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 176.62  E-value: 1.97e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   3 EPTSRRPAYSRLLDRAVRILAVRDHSEQELRRKLSAPvmskngpediDATAEDYDRVVAWCYEHHYLDDGRFAARFLASR 82
Cdd:PRK00117   2 EDTARRRMYASARARALRLLARREHSRAELRRKLAAK----------GFSEEVIEAVLDRLKEEGLLDDERFAESFVRSR 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199  83 GRKGYGPARIRQELNQKGVARESIEKAMRESEIDWCELAREQAVRKYGEPLPREFSEKVKIQRFLLYRGFLMEDIQDIWR 162
Cdd:PRK00117  72 ARKGYGPRRIRQELRQKGVDREIIEEALAELDIDWEELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLR 151

                 ....
gi 515952199 163 NFTD 166
Cdd:PRK00117 152 NALD 155
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
7-166 6.21e-41

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 134.53  E-value: 6.21e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   7 RRPAYSRLLDRAVRILAVRDHSEQELRRKLSAPVMSkngPEDIDAtaedydrVVAWCYEHHYLDDGRFAARFLASR-GRK 85
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFD---EEEIEE-------VLDRLKEEGYLDDERFAESYVRSRlRRK 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199  86 GYGPARIRQELNQKGVARESIEKAMRE-SEIDWCELAREQAVRKYGEPLPRE-FSEKVKIQRFLLYRGFLMEDIQDIWRN 163
Cdd:COG2137   71 GYGPRRIRQELRQKGIDEELIEEALEElDEEDELEAARELARKKFGSLKPLDpAKEKQKLARFLARRGFSSDLIRRVLRE 150

                 ...
gi 515952199 164 FTD 166
Cdd:COG2137  151 LLE 153
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
50-163 2.26e-28

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 101.51  E-value: 2.26e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   50 DATAEDYDRVVAWCYEHHYLDDGRFAARFLASRGR-KGYGPARIRQELNQKGVARESIEKAMreSEIDWCEL-AREQAVR 127
Cdd:pfam02631   5 GFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARtRGKGPRRIRQELRQKGVDEEIIEEAL--EEFDEEEQiARELAEK 82
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 515952199  128 KYGEPLPR-EFSEKVKIQRFLLYRGFLMEDIQDIWRN 163
Cdd:pfam02631  83 KFKRYPAEsDRKLKQKLIRFLARRGFSSEVIRAALQE 119
recX PRK14135
recombination regulator RecX; Provisional
10-160 1.78e-13

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 66.00  E-value: 1.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199  10 AYSRLLDRAVRILAVRDHSEQELRRKLsapvmskngpEDIDATAEDYDRVVAWCYEHHYLDDGRFAARFLASR---GRKG 86
Cdd:PRK14135  55 QVSKGKNLALYYLSYQMRTEKEVRDYL----------KKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNintGDKG 124
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515952199  87 ygPARIRQELNQKGVARESIEKAMRE-SEIDWCELAREQA---VRKYGEPLPREFSEKVKIQrfLLYRGFLMEDIQDI 160
Cdd:PRK14135 125 --PRVIKQKLLQKGIEDEIIEEALSEyTEEDQIEVAQKLAeklLKKYQKLPFKALKQKIIQS--LLTKGFSYEVIKAA 198
recX PRK14136
recombination regulator RecX; Provisional
2-152 5.10e-10

recombination regulator RecX; Provisional


Pssm-ID: 237620 [Multi-domain]  Cd Length: 309  Bit Score: 56.55  E-value: 5.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   2 SEPTSRRPAYSrLLDRAVRILAVRDHSEQELRRKLSAPVMSKNGPEDI-DATAEDydrvvawcyehHYLDDGRFAARFLA 80
Cdd:PRK14136 153 RSRASSRPARS-LKGRALGYLSRREYSRAELARKLAPYADESDSVEPLlDALERE-----------GWLSDARFAESLVH 220
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515952199  81 SRGRKgYGPARIRQELNQKGVAR---ESIEKAMRESeidwcELAREQAV-RKYGEPLPREFSEKVKIQRFLLYRGF 152
Cdd:PRK14136 221 RRASR-VGSARIVSELKRHAVGDalvESVGAQLRET-----EFERAQAVwRKKFGALPQTPAERAKQARFLAARGF 290
recX PRK14137
recombination regulator RecX; Provisional
4-110 5.52e-03

recombination regulator RecX; Provisional


Pssm-ID: 172626  Cd Length: 195  Bit Score: 35.73  E-value: 5.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952199   4 PTSRRPAYSRLLDRAVRILAVRDHSEQELRRKLsapvmsKNGPEDIDATAEDYDRVvawcYEHHYLDDGRFAArflASRG 83
Cdd:PRK14137  32 PPTPDEAREALLAYAFRALAARAMTAAELRAKL------ERRSEDEALVTEVLERV----QELGYQDDAQVAR---AENS 98
                         90       100
                 ....*....|....*....|....*..
gi 515952199  84 RKGYGPARIRQELNQKGVARESIEKAM 110
Cdd:PRK14137  99 RRGVGALRVRQTLRRRGVEETLIEETL 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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