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Conserved domains on  [gi|515951937|ref|WP_017382520|]
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MULTISPECIES: TonB-dependent siderophore receptor [Enterobacter]

Protein Classification

TonB-dependent siderophore receptor( domain architecture ID 11486670)

TonB-dependent siderophore receptor acts as a channel to allow import of iron-siderophore complexes, such as Escherichia coli ferrienterobactin receptor, which is involved in the initial step of iron uptake by binding ferrienterobactin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-749 0e+00

FepA family TonB-dependent siderophore receptor;


:

Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1450.23  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   1 MNKKIHSLALLVNLGIYGVALPVMADDNT---ASAQHEDTMVITAAEQNLQAPGVSTITADEIRKNPPARDVAEIIRTMP 77
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKtddTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  78 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRLGWRGERDTRGDTGWVPPEMIERIEVIRGPAAARY 157
Cdd:PRK13524  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 158 GNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGDFSFRMYGNLDKTQADAWDINQGHQSDR 237
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 238 TGAYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNsssgLVKKNYGKETNRIYRQNF 317
Cdd:PRK13524 241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDA----LVKSLYGKETNRMYRQNY 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 318 AVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEGLFNSN--KFTDTDLADVMLHSEINLPIDFIVNQNLTLGTEWN 395
Cdd:PRK13524 317 ALTHRGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKatQFSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWN 396
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 396 QQRMKDSTSFTQTQ-QGGTIPGMS-EDRSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLG 473
Cdd:PRK13524 397 QQRMKDPSSNTQALtSGGAIPGVSaTGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLG 476
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 474 DDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGvGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRND 553
Cdd:PRK13524 477 DDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAGN-GCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRND 555
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 554 YRNKIEAGYAPIGQTSTGKvtTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKETGDRLSIIPEYTLN 633
Cdd:PRK13524 556 YRNKIEAGYVPVGTNSVGK--TDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLN 633
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 634 STLSWQVHQDVSLQSTFTWYGKQQPKKYNYKGQPVTGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGN 713
Cdd:PRK13524 634 STLSWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGN 713
                        730       740       750
                 ....*....|....*....|....*....|....*.
gi 515951937 714 AQTTGNTttgayMYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:PRK13524 714 AQTTGDL-----IAGAGAYTYNEPGRTYYMSLNTHF 744
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-749 0e+00

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1450.23  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   1 MNKKIHSLALLVNLGIYGVALPVMADDNT---ASAQHEDTMVITAAEQNLQAPGVSTITADEIRKNPPARDVAEIIRTMP 77
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKtddTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  78 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRLGWRGERDTRGDTGWVPPEMIERIEVIRGPAAARY 157
Cdd:PRK13524  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 158 GNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGDFSFRMYGNLDKTQADAWDINQGHQSDR 237
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 238 TGAYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNsssgLVKKNYGKETNRIYRQNF 317
Cdd:PRK13524 241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDA----LVKSLYGKETNRMYRQNY 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 318 AVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEGLFNSN--KFTDTDLADVMLHSEINLPIDFIVNQNLTLGTEWN 395
Cdd:PRK13524 317 ALTHRGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKatQFSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWN 396
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 396 QQRMKDSTSFTQTQ-QGGTIPGMS-EDRSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLG 473
Cdd:PRK13524 397 QQRMKDPSSNTQALtSGGAIPGVSaTGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLG 476
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 474 DDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGvGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRND 553
Cdd:PRK13524 477 DDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAGN-GCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRND 555
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 554 YRNKIEAGYAPIGQTSTGKvtTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKETGDRLSIIPEYTLN 633
Cdd:PRK13524 556 YRNKIEAGYVPVGTNSVGK--TDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLN 633
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 634 STLSWQVHQDVSLQSTFTWYGKQQPKKYNYKGQPVTGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGN 713
Cdd:PRK13524 634 STLSWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGN 713
                        730       740       750
                 ....*....|....*....|....*....|....*.
gi 515951937 714 AQTTGNTttgayMYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:PRK13524 714 AQTTGDL-----IAGAGAYTYNEPGRTYYMSLNTHF 744
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
51-749 1.07e-128

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 396.82  E-value: 1.07e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  51 GVSTITADEIRKNPpARDVAEIIRTMPGVNLTGNStsgqRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRlgwrgerd 130
Cdd:cd01347    1 SVSVITAEDIEKQP-ATSLADLLRRIPGVSVTRGG----GGGGSTISIRGFGPDRTLVLVDGLPLASSNYGR-------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 131 tRGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEhkdEGSTKRTNFSLSGPLGGD 210
Cdd:cd01347   68 -GVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDN---SGSSGGGGFDVSGALADD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 211 FSFRMYGNLDKTQADAWdinqghqsdrtgaYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQN 290
Cdd:cd01347  144 GAFGARLYGAYRDGDGT-------------IDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLP 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 291 TNNDNSSSGLVKK-----NYGKETNRIYRQNFAVTWNGGW-DNGITTSNWAQYEHTRNSRLGEGLAGGLEGLF----NSN 360
Cdd:cd01347  211 ANGTGSSLGGGPSsntngDRDWDYRDRYRKRASLGLEHDLnDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGgdlgRSG 290
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 361 KFTDTDLADVMLHSEINLPID-FIVNQNLTLGTEWNQQRmkdstsFTQTQqggtipgmsedrspytsaeiFSLFAENNME 439
Cdd:cd01347  291 YSSERDTTQLGFDAGLNAPFGtGPVAHTLTLGVEYRREE------LDEKQ--------------------TALYAQDTIE 344
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 440 LTDSTMLTPALRFDHHTI--------------VGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYLLYskgq 505
Cdd:cd01347  345 LTDDLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHG---- 420
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 506 gcyassdgvGCYMMGNDDLKAETSINKEIGLEWKRD-GWLAGVTWFRNDYRNKIEAGYAPIGQTStgkvttdIYQWENVP 584
Cdd:cd01347  421 ---------GTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVSTPTNTGLGL-------VTVYVNGG 484
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 585 KAVVEGLEGSLNVPVSDTINWTNNITYM----LQSKNKETGDRLSIIPEYTLNSTLSWQVHQD-VSLQSTFTWYGKQQPK 659
Cdd:cd01347  485 KARIRGVELEASYDLTDGLGLTGSYTYTdtevKRTDGATTGNRLPGIPKHTANLGLDYELPDEgLTAGGGVRYRGKQYAD 564
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 660 KYNykgqpvtGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAqttgntttgaymYGAGAYTYNEPGR 739
Cdd:cd01347  565 TAN-------GNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSV------------RGSGLYGYYGPGR 625
                        730
                 ....*....|
gi 515951937 740 TWYMSVNTRF 749
Cdd:cd01347  626 TYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
25-697 3.03e-120

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 373.81  E-value: 3.03e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  25 ADDNTASAQHEDTMVITA---AEQNLQAPG-VSTITADEIRKNPpARDVAEIIRTMPGVNLTgnsTSGQRGNNRQIDIRG 100
Cdd:COG4771   17 ADALAEDATELEEVVVTAtrtEQSLSDAPAsVSVITAEEIEKLG-ATDLADALRLLPGVSVT---RSGGRGGSSGISIRG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 101 MGPENTLILIDGKPVTSRNsirlgwrgeRDTRGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGS 180
Cdd:COG4771   93 LGGDRVLVLIDGVPVNNPA---------LGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGS 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 181 WNTYLNAPEHkdegSTKRTNFSLSGPlGGDFSFRMYGNldktqadawdinqGHQSDRTGAYADTLPAGREGVENKDINGV 260
Cdd:COG4771  164 VSLGYGSNGN----GTYSGSLSLGGP-GDKLSFLLSGS-------------YRDRDGYLDYRNGGFVGNSGYERYNLNAK 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 261 VRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNSSsglvkkNYGKETNRIYRQNFAVTWNGGWDNGITTSnwAQYEHT 340
Cdd:COG4771  226 LGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSD------NAGDRDTTTDRGNYSLRYNGDLGDNLDLS--LYYSRT 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 341 RNSRlgeglaGGLEGLFNSNKFTDTDLADVMLHSEINLPIDfiVNQNLTLGTEWNQQRMKDSTSFTQTQQggtipgmsed 420
Cdd:COG4771  298 DRDS------TNGSLGGSTGSFSDSDDTTYGLELDLTYPLG--GNHTLTLGAEYRYDDLDSSSFLGGADA---------- 359
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 421 rspytSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVG----NNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNP 496
Cdd:COG4771  360 -----SRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYG 434
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 497 NYLLYSkgqgcyassdgvGCYMMGNDDLKAETSINKEIGLEWK--RDGWLAGVTWFRNDYRNKIEagyapigQTSTGKVT 574
Cdd:COG4771  435 SGTGTP------------GRYVLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDLIV-------LVPVGPGP 495
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 575 TDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYmLQSKNK--ETGDRLSIIPEYTLNSTLSWQVHQDVSLQSTFTW 652
Cdd:COG4771  496 GDVLQYENVGKARTYGLELELKYRLGKGLTLTASYTY-LDSKIDdgDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRY 574
                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....*
gi 515951937 653 YGKQQPkkynykgQPVTGSEKDEVSPYSIVGLSATWDVTKNVSLT 697
Cdd:COG4771  575 YGGRYV-------TPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
52-749 2.35e-111

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 352.10  E-value: 2.35e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   52 VSTITADEIRKNPpARDVAEIIRTMPGVNLTGNSTSGQRGNnrqIDIRGMGPEntlILIDGkpvTSRNSIRLGWRGERDt 131
Cdd:TIGR01783   6 VSVITRQELEDQQ-AGSLSEALQRVPGVVVGGSGGTTQFGN---ITIRGFGLE---VDIDN---VYLDGVPLLSRGNLA- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  132 rgdtgWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSwntylnAPEHKDEGSTKRTNFSLSGPLGGDF 211
Cdd:TIGR01783  75 -----IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGS------VTFGAGTRSGYRTAFDLGGPLGADG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  212 SFRMYGNLDKTQADAWDINQGHqsdRTGAYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEA-----GYSRQNNLYAG 286
Cdd:TIGR01783 144 TFRGRLNGARQDGDSFYDGAGE---ETRLGATATDWQLDDRTLLRLGAYYQKERDRGGYGGLPAsggtsGRDLSSDRYLG 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  287 DTQNTNNDNSSSglvkKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEGlfNSNKFTDTD 366
Cdd:TIGR01783 221 TSSNRNYDDREY----LSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVN--VKQDRVQID 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  367 LADVMLHSEINLPIDFIVNQ-NLTLGTE-WNQQRMKDS--TSFTQTQQGGTIPGMS-EDRSPYTSAEIFSLFAENNMELT 441
Cdd:TIGR01783 295 AGLDGEFETGPIEHDLLLGVsYGQRTTNrFNNTGYPSDniYSLTATSSARTDIGDSpKDRALSSTTKALNGVALQRILLA 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  442 DSTMLTPALRFDHHTIVGNNwspSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGVgcymmGN 521
Cdd:TIGR01783 375 DKWTLTLGGRYDSVDVKSNN---GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN-----SG 446
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  522 DDLKAETSINKEIGLEWKR-DGWLAGVTWFRNDYRNKIEAGYApigqTSTGKVTTDIYQWENVPKAVVEGLegSLNVPVS 600
Cdd:TIGR01783 447 DILEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQDPV----NGTFSVNAGKTRNRGVELEARGYL--TPGLSLS 520
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  601 DTINWTNNITYMLqSKNKETGDRLSIIPEYTLNSTLSWQVhQDVSLQSTFTWYGKQQPKKYNYKGqpvtgsEKDEVSPYS 680
Cdd:TIGR01783 521 AGYTYTDAEFTED-TNGDTQGNTVPFVPKHTASLWASYAP-PVGDNGLTLGGGVQYTGKAYVDGG------NTGKVPSYT 592
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515951937  681 IVGLSATWDVT--KNVSLTGGVDNVFDKRQWRAGnaqttgntttgaYMYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:TIGR01783 593 VVDLSVRYDLTkkKNLTLALNVNNLFDRDYYTSG------------YRWGPSAYIYPGAPRTVGLSVSYDF 651
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
276-748 6.04e-46

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 171.11  E-value: 6.04e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  276 GYSRQNNLYAGDTQNTNNDNSSSGLVKKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEG 355
Cdd:pfam00593  26 DGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAG 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  356 LFNSNKFTDTDLADVmlhseINLPIDFIVNQNLTLGTEWNQQRMKDSTSFTQTQQGGTIPGMSEDRSPYTSAEIFSLFAE 435
Cdd:pfam00593 106 DYLSDDRLYGLYGLD-----GDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQ 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  436 NNMELTDSTMLTPALRFDHHTIVGNN--------------WSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYlly 501
Cdd:pfam00593 181 DNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSG--- 257
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  502 skgqgcyaSSDGVGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRNDYRNKIEAgyapigQTSTGKVTTDIYQWE 581
Cdd:pfam00593 258 --------SGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITS------DPDGPGLGGTVYTYT 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  582 NVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKE---TGDRLSIIPEYTLNSTLSWQVHQD---VSLQSTFTWYGK 655
Cdd:pfam00593 324 NVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADaddTGNPLPNVPRHTANLGLTYDFPLGgwgARLGARYVGSGE 403
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  656 QQPKKYNykgqpvtgsEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAQttgntttgaymyGAGAYTYN 735
Cdd:pfam00593 404 RRYGDAA---------NTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSG------------GGNLGGYP 462
                         490
                  ....*....|...
gi 515951937  736 EPGRTWYMSVNTR 748
Cdd:pfam00593 463 GPGRTFYLGLSYK 475
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-749 0e+00

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1450.23  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   1 MNKKIHSLALLVNLGIYGVALPVMADDNT---ASAQHEDTMVITAAEQNLQAPGVSTITADEIRKNPPARDVAEIIRTMP 77
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKtddTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  78 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRLGWRGERDTRGDTGWVPPEMIERIEVIRGPAAARY 157
Cdd:PRK13524  81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 158 GNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGDFSFRMYGNLDKTQADAWDINQGHQSDR 237
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 238 TGAYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNsssgLVKKNYGKETNRIYRQNF 317
Cdd:PRK13524 241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDA----LVKSLYGKETNRMYRQNY 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 318 AVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEGLFNSN--KFTDTDLADVMLHSEINLPIDFIVNQNLTLGTEWN 395
Cdd:PRK13524 317 ALTHRGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKatQFSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWN 396
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 396 QQRMKDSTSFTQTQ-QGGTIPGMS-EDRSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLG 473
Cdd:PRK13524 397 QQRMKDPSSNTQALtSGGAIPGVSaTGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLG 476
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 474 DDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGvGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRND 553
Cdd:PRK13524 477 DDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAGN-GCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRND 555
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 554 YRNKIEAGYAPIGQTSTGKvtTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKETGDRLSIIPEYTLN 633
Cdd:PRK13524 556 YRNKIEAGYVPVGTNSVGK--TDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLN 633
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 634 STLSWQVHQDVSLQSTFTWYGKQQPKKYNYKGQPVTGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGN 713
Cdd:PRK13524 634 STLSWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGN 713
                        730       740       750
                 ....*....|....*....|....*....|....*.
gi 515951937 714 AQTTGNTttgayMYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:PRK13524 714 AQTTGDL-----IAGAGAYTYNEPGRTYYMSLNTHF 744
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
5-749 0e+00

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 972.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   5 IHSLALLVNLGIYGVALPVMADDNTASAQHEDTMVITAAEQNL-QAPGVSTITADEIRKNPPARDVAEIIRTMPGVNLTG 83
Cdd:PRK13528   5 VNKILWLLTVLLVGLNSPVSAAESSDDDNGETMVVEATAEQELkQQPGVSIITAEDIKKRPPVNDLSDIIRKMPGVNLTG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  84 NSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRLGWRGERDTRGDTGWVPPEMIERIEVIRGPAAARYGNGAAG 163
Cdd:PRK13528  85 NSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEVIRGPAAARYGSGAAG 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 164 GVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGD-FSFRMYGNLDKTQADAWDINQGHQSdrtgaya 242
Cdd:PRK13528 165 GVVNIITKRPTNDWHGSLSLYTNQPESSKEGATRRANFSLSGPLAGDaLTMRLYGNLNKTDADSWDINSSAGT------- 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 243 dTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNSSSGLVKKnyGKETNRIYRQNFAVTWN 322
Cdd:PRK13528 238 -KNAAGREGVRNKDINGVLSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSSAVTESLAKS--GKETNRLYRQNYGLTHN 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 323 GGWDNGiTTSNWAQYEHTRNSRLGEGLAGGLEGLFNSN-KFTDTDLADVMLHSEINLPIDFIVNQNLTLGTEWNQQRMKD 401
Cdd:PRK13528 315 GIWDWG-QSRLGFYYEKTNNTRMNEGLAGGGEGRITADqTFTTSRLESYRTSGELNVPLNWLFEQTLTVGAEWNRDELND 393
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 402 STSFTQTQQGGTIPGMSED---RSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTL 478
Cdd:PRK13528 394 PSSTSLTVKDGDIGGISGSaadRSSKNKSEISALYVEDNIEPVPGTNLIPGLRFDYHSEFGSNWSPSLNLSQELGDYFKV 473
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 479 KMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGVGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRNDYRNKI 558
Cdd:PRK13528 474 KAGIARAFKAPNLYQSSEGYLLYSRGNGCPKDITSGGCYLVGNKNLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQNKI 553
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 559 EAGYAPIGQTSTGkvtTDIYQWENVPKAVVEGLEGSLNVPV-SDTINWTNNITYMLQSKNKETGDRLSIIPEYTLNSTLS 637
Cdd:PRK13528 554 VAGDDVIGRTASG---AYILQWQNGGKAVVEGLEGNLLVPLmKDRLNWNTNATYMITSEQKDTGNPLSVIPKYTINSTLD 630
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 638 WQVHQDVSLQSTFTWYGKQQPKKYNYKGQPVT-GSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNaqt 716
Cdd:PRK13528 631 WQITQALSANVNWTLYGKQKPRTHAESRSEETgGLSGKELGAYSLVGVNVNYDINKNLRLNVGVSNLFDKQIYREGE--- 707
                        730       740       750
                 ....*....|....*....|....*....|...
gi 515951937 717 tgntttgaymygaGAYTYNEPGRTWYMSVNTRF 749
Cdd:PRK13528 708 -------------GANTYNEPGRAYYAGVTASF 727
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
51-749 1.07e-128

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 396.82  E-value: 1.07e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  51 GVSTITADEIRKNPpARDVAEIIRTMPGVNLTGNStsgqRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRlgwrgerd 130
Cdd:cd01347    1 SVSVITAEDIEKQP-ATSLADLLRRIPGVSVTRGG----GGGGSTISIRGFGPDRTLVLVDGLPLASSNYGR-------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 131 tRGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEhkdEGSTKRTNFSLSGPLGGD 210
Cdd:cd01347   68 -GVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDN---SGSSGGGGFDVSGALADD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 211 FSFRMYGNLDKTQADAWdinqghqsdrtgaYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQN 290
Cdd:cd01347  144 GAFGARLYGAYRDGDGT-------------IDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLP 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 291 TNNDNSSSGLVKK-----NYGKETNRIYRQNFAVTWNGGW-DNGITTSNWAQYEHTRNSRLGEGLAGGLEGLF----NSN 360
Cdd:cd01347  211 ANGTGSSLGGGPSsntngDRDWDYRDRYRKRASLGLEHDLnDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGgdlgRSG 290
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 361 KFTDTDLADVMLHSEINLPID-FIVNQNLTLGTEWNQQRmkdstsFTQTQqggtipgmsedrspytsaeiFSLFAENNME 439
Cdd:cd01347  291 YSSERDTTQLGFDAGLNAPFGtGPVAHTLTLGVEYRREE------LDEKQ--------------------TALYAQDTIE 344
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 440 LTDSTMLTPALRFDHHTI--------------VGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYLLYskgq 505
Cdd:cd01347  345 LTDDLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHG---- 420
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 506 gcyassdgvGCYMMGNDDLKAETSINKEIGLEWKRD-GWLAGVTWFRNDYRNKIEAGYAPIGQTStgkvttdIYQWENVP 584
Cdd:cd01347  421 ---------GTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVSTPTNTGLGL-------VTVYVNGG 484
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 585 KAVVEGLEGSLNVPVSDTINWTNNITYM----LQSKNKETGDRLSIIPEYTLNSTLSWQVHQD-VSLQSTFTWYGKQQPK 659
Cdd:cd01347  485 KARIRGVELEASYDLTDGLGLTGSYTYTdtevKRTDGATTGNRLPGIPKHTANLGLDYELPDEgLTAGGGVRYRGKQYAD 564
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 660 KYNykgqpvtGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAqttgntttgaymYGAGAYTYNEPGR 739
Cdd:cd01347  565 TAN-------GNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSV------------RGSGLYGYYGPGR 625
                        730
                 ....*....|
gi 515951937 740 TWYMSVNTRF 749
Cdd:cd01347  626 TYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
25-697 3.03e-120

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 373.81  E-value: 3.03e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  25 ADDNTASAQHEDTMVITA---AEQNLQAPG-VSTITADEIRKNPpARDVAEIIRTMPGVNLTgnsTSGQRGNNRQIDIRG 100
Cdd:COG4771   17 ADALAEDATELEEVVVTAtrtEQSLSDAPAsVSVITAEEIEKLG-ATDLADALRLLPGVSVT---RSGGRGGSSGISIRG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 101 MGPENTLILIDGKPVTSRNsirlgwrgeRDTRGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGS 180
Cdd:COG4771   93 LGGDRVLVLIDGVPVNNPA---------LGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGS 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 181 WNTYLNAPEHkdegSTKRTNFSLSGPlGGDFSFRMYGNldktqadawdinqGHQSDRTGAYADTLPAGREGVENKDINGV 260
Cdd:COG4771  164 VSLGYGSNGN----GTYSGSLSLGGP-GDKLSFLLSGS-------------YRDRDGYLDYRNGGFVGNSGYERYNLNAK 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 261 VRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNSSsglvkkNYGKETNRIYRQNFAVTWNGGWDNGITTSnwAQYEHT 340
Cdd:COG4771  226 LGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSD------NAGDRDTTTDRGNYSLRYNGDLGDNLDLS--LYYSRT 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 341 RNSRlgeglaGGLEGLFNSNKFTDTDLADVMLHSEINLPIDfiVNQNLTLGTEWNQQRMKDSTSFTQTQQggtipgmsed 420
Cdd:COG4771  298 DRDS------TNGSLGGSTGSFSDSDDTTYGLELDLTYPLG--GNHTLTLGAEYRYDDLDSSSFLGGADA---------- 359
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 421 rspytSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVG----NNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNP 496
Cdd:COG4771  360 -----SRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYG 434
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 497 NYLLYSkgqgcyassdgvGCYMMGNDDLKAETSINKEIGLEWK--RDGWLAGVTWFRNDYRNKIEagyapigQTSTGKVT 574
Cdd:COG4771  435 SGTGTP------------GRYVLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDLIV-------LVPVGPGP 495
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 575 TDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYmLQSKNK--ETGDRLSIIPEYTLNSTLSWQVHQDVSLQSTFTW 652
Cdd:COG4771  496 GDVLQYENVGKARTYGLELELKYRLGKGLTLTASYTY-LDSKIDdgDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRY 574
                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....*
gi 515951937 653 YGKQQPkkynykgQPVTGSEKDEVSPYSIVGLSATWDVTKNVSLT 697
Cdd:COG4771  575 YGGRYV-------TPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
52-749 2.35e-111

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 352.10  E-value: 2.35e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   52 VSTITADEIRKNPpARDVAEIIRTMPGVNLTGNSTSGQRGNnrqIDIRGMGPEntlILIDGkpvTSRNSIRLGWRGERDt 131
Cdd:TIGR01783   6 VSVITRQELEDQQ-AGSLSEALQRVPGVVVGGSGGTTQFGN---ITIRGFGLE---VDIDN---VYLDGVPLLSRGNLA- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  132 rgdtgWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSwntylnAPEHKDEGSTKRTNFSLSGPLGGDF 211
Cdd:TIGR01783  75 -----IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGS------VTFGAGTRSGYRTAFDLGGPLGADG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  212 SFRMYGNLDKTQADAWDINQGHqsdRTGAYADTLPAGREGVENKDINGVVRWDFAPMQSLEFEA-----GYSRQNNLYAG 286
Cdd:TIGR01783 144 TFRGRLNGARQDGDSFYDGAGE---ETRLGATATDWQLDDRTLLRLGAYYQKERDRGGYGGLPAsggtsGRDLSSDRYLG 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  287 DTQNTNNDNSSSglvkKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEGlfNSNKFTDTD 366
Cdd:TIGR01783 221 TSSNRNYDDREY----LSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVN--VKQDRVQID 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  367 LADVMLHSEINLPIDFIVNQ-NLTLGTE-WNQQRMKDS--TSFTQTQQGGTIPGMS-EDRSPYTSAEIFSLFAENNMELT 441
Cdd:TIGR01783 295 AGLDGEFETGPIEHDLLLGVsYGQRTTNrFNNTGYPSDniYSLTATSSARTDIGDSpKDRALSSTTKALNGVALQRILLA 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  442 DSTMLTPALRFDHHTIVGNNwspSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGVgcymmGN 521
Cdd:TIGR01783 375 DKWTLTLGGRYDSVDVKSNN---GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN-----SG 446
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  522 DDLKAETSINKEIGLEWKR-DGWLAGVTWFRNDYRNKIEAGYApigqTSTGKVTTDIYQWENVPKAVVEGLegSLNVPVS 600
Cdd:TIGR01783 447 DILEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQDPV----NGTFSVNAGKTRNRGVELEARGYL--TPGLSLS 520
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  601 DTINWTNNITYMLqSKNKETGDRLSIIPEYTLNSTLSWQVhQDVSLQSTFTWYGKQQPKKYNYKGqpvtgsEKDEVSPYS 680
Cdd:TIGR01783 521 AGYTYTDAEFTED-TNGDTQGNTVPFVPKHTASLWASYAP-PVGDNGLTLGGGVQYTGKAYVDGG------NTGKVPSYT 592
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515951937  681 IVGLSATWDVT--KNVSLTGGVDNVFDKRQWRAGnaqttgntttgaYMYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:TIGR01783 593 VVDLSVRYDLTkkKNLTLALNVNNLFDRDYYTSG------------YRWGPSAYIYPGAPRTVGLSVSYDF 651
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
7-749 4.09e-109

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 346.49  E-value: 4.09e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   7 SLALLVNLGIYGVALpVMADDNTASAQHEDTMVITAA--EQNLQ-APG-VSTITADEIRKNPpARDVAEIIRTMPGVNLT 82
Cdd:PRK10064   3 RLNPFVRVGLCASAI-SCAWPVLAVDDDGETMVVTASavEQNLKdAPAsISVITQEDLQRKP-VQNLKDVLKEVPGVQLT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  83 GNSTsgqrgNNRQIDIRGMGPENTLILIDGKPVTSRNSIRlgwrgeRDTRGDTGWVPPEMIERIEVIRGPAAARYGNGAA 162
Cdd:PRK10064  81 NEGD-----NRKGVSIRGLDSSYTLILIDGKRVNSRNAVF------RHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDAL 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 163 GGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPL-GGDFSFRMYGNLDKTQADAwdiNQGHQSDRTGay 241
Cdd:PRK10064 150 GGVVNIITKKIGQKWHGTVTVDTTIQEHRDRGDTYNGQFFTSGPLiDGVLGMKAYGSLAKREKDD---PQNSTTTDTG-- 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 242 adtLPAGREGVENKDINGVVRWdfAPMQSLEFEAGY--SRQnnlyagdtqntnnDNSSSGLVKknygketNRIYRQNFAV 319
Cdd:PRK10064 225 ---ETPRIEGFTSRDGNVEFAW--TPNQNHDFTAGYgfDRQ-------------DRDSDSLDK-------NRLERQNYSL 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 320 TWNGGWDNGitTSNWAQY-EHTRNSRLGeglaggleglfNSNKFTDTDLAdvmLHSEINLPIDFIvNQNLTLGTEWNQQR 398
Cdd:PRK10064 280 SHNGRWDYG--NSELKYYgEKVENKNPG-----------NSSPITSESNS---IDGKYTLPLTAI-NQFLTFGGEWRHDK 342
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 399 MKDSTSFTqtqqGGTipgmsedrSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTL 478
Cdd:PRK10064 343 LSDAVNLT----GGT--------SSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTV 410
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 479 KMGIARAYKAPSLYQTNPNYLlyskgqgcyASSDGVGCYMMGNDDLKAETSINKEIGLEWK-RDGWLAGV----TWFRND 553
Cdd:PRK10064 411 KGGWATAFKAPSLLQLSPDWT---------SNSCRGACKIVGSPDLKPETSESWELGLYYMgEEGWLEGVessvTVFRND 481
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 554 YRNKI------EAGYAP-----IGQTSTGKVTTD-IYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYmLQSKNKETG 621
Cdd:PRK10064 482 VDDRIsisrtsDVNAAPgyqnfVGFETNGRGRRVpVFRYYNVNKARIQGVETELKIPFNDEWKLSLNYTY-NDGRDVSNG 560
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 622 DR--LSIIPEYTLNSTLSWQVHQdvSLQSTFTWYGkqqpkkyNYKGQPVTGSEkDEVSP--YSIVGLSATWDVTKNVSLT 697
Cdd:PRK10064 561 ENkpLSDLPFHTANGTLDWKPLA--LEDWSFYVSG-------NYTGQKRADSA-TAKTPggYTIWNTGAAWQVTKDVKLR 630
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|..
gi 515951937 698 GGVDNVFDKRQWRagnaqttgntttgaymygaGAYTYNEPGRTWYMSVNTRF 749
Cdd:PRK10064 631 AGVLNLGDKDLSR-------------------DDYSYNEDGRRYFMAVDYRF 663
PRK13483 PRK13483
ligand-gated channel protein;
1-749 3.98e-90

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 296.30  E-value: 3.98e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   1 MNKKIHSLALLVNLGIYGVALPVMADDNTASAQheDTMVITAA--EQNLQ-APG-VSTITADEIrKNPPARDVAEIIRTM 76
Cdd:PRK13483   1 MKKYLAQVISALCLLPAVFVTHALAQAAPDKTM--ETVVVTASgyEQQIRdAPAsISVITREDL-ENRFYRDLTDALLDV 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  77 PGVNLTGNstsgqrGNNRQIDIRGMGPENTLILIDGKPVTSRNSirlgwRGERDTRG-DTGWVPP-EMIERIEVIRGPAA 154
Cdd:PRK13483  78 PGVVVTGG------GDRTDISLRGMGSQYTLILVDGKRQSSRET-----RPNSDGPGvEQAWTPPlAAIERIEVIRGPMS 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 155 ARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGD-FSFRMYGNLDKTQADawDINQGH 233
Cdd:PRK13483 147 SLYGSDAIGGVINIITRKVPNEWQGEVRLDTTLQENSDSGNVYQANFFVNGPLIKDlLGLQLYGQYTQREED--DIEGGY 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 234 QsDRTgayADTLPAGREGVENKDingvvrwdfapmQSLEFEAGYSRQN-NLYAGDTQNTNNDNSSSGlvKKNYGKETNRI 312
Cdd:PRK13483 225 R-DKD---ARSLTAKLALTPNED------------HDIMLEVGTSNQErDSTVGKTVAPLAPGESCG--RRGCPESSTTE 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 313 YRQN-FAVTWNGGWDNGiTTSNWAQYEHTRN-SRLGeglaggleglfnsnKFTDTDladvmLHSEINLPIDfiVNQNLTL 390
Cdd:PRK13483 287 YERStVSLSHTGRWDFG-TSDTYIQHEEFDNkSREM--------------KIKNTD-----FQSSLVAPLG--QEHTLTF 344
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 391 GTEWNQQRMKDSTSftqtqqgGTIPGMSEdrspyTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQ 470
Cdd:PRK13483 345 GAAYNHQDLTDETS-------NQISDLTD-----ISRTQWAVFSEDEWRIADDFALTGGLRLDHDENFGGHVSPRVYGVW 412
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 471 GLGDDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYassdgvgcymmGNDDLKAETSINKEIGLEW-KRDGWLAGVTW 549
Cdd:PRK13483 413 NLAPSWTVKGGVSTGFRAPSLRQTTPDWGQVSRGGNIY-----------GNPDLKPETSLNKELGLYYdLGSGLTASLTV 481
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 550 FRNDYRNKIEAGYAPIGQTSTG------KVTTDIyqweNVPKAVVEGLEGSLNVPVSDTINWTNNITYMlQSKNKE---T 620
Cdd:PRK13483 482 FYNEFKDKITRVACPATQCTDGpnqfgaDPTTYV----NIDEAVTQGVEASLSYPITSTLSLSGNYTYT-DSEQKSgayK 556
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 621 GDRLSIIPEYTLNSTLSWQVHQDVSlqstfTWygkqqpKKYNYKG---QPVTG-SEKDEVSP-YSIVGLSATWDVTKNVS 695
Cdd:PRK13483 557 GSPLNQLPKHLFQASLNWEPTDRLN-----SW------ARVNYRGeesQPTTGpSSSSFIAPsYTFLDLGANYQLTDNLK 625
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....
gi 515951937 696 LTGGVDNVFDKRqwragnaqttgntttgaymYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:PRK13483 626 LSAGIYNLFDKE-------------------INYEEYGYVEDGRRYWLGMTYSF 660
PRK13513 PRK13513
ligand-gated channel protein;
3-707 3.67e-89

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 293.60  E-value: 3.67e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   3 KKIHSLALLVnlgIYGVALPVMADDNTASAQHEDTMVITAA--EQNLQ-APG-VSTITADEIRKNPpARDVAEIIRTMPG 78
Cdd:PRK13513   6 RKTHKAALVI---AAAISSQAYAAEKTNTATPTDTMVVTASgfQQRIQdAPAsISVVTREQLENKA-YRDVTDALKDVPG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  79 VNLTGNstsgqrGNNRQIDIRGMGPENTLILIDGKPVTSRNSirlgwRGERDTRG-DTGWVPP-EMIERIEVIRGPAAAR 156
Cdd:PRK13513  82 VVVTGG------GSTSDISIRGMAAKYTLILVDGKRVDTRST-----RPNSDGSGiEQGWLPPlAAIERIEVVRGPMSSL 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 157 YGNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPL-GGDFSFRMYGNLDKTQADawdinqghqs 235
Cdd:PRK13513 151 YGSDAMGGVINIITRKVQKEWHGSLRADATLQEDSKSGDIFQTNAYASGPLiDGLLGLKVSGLLSHRSED---------- 220
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 236 DRTGAYAdtlpagregvENKDINGVVRWDFAP--MQSLEFEAGYSRQN-NLYAGDTQNTNNDNSssglvkknygkeTNRI 312
Cdd:PRK13513 221 KIIDGYN----------EQRMRNGTATFSLTPddNNEFDFEIGRYVQDrNSTPGRTLALNGTNS------------DTQY 278
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 313 YRQNFAVTWNGGWDNGITTSnWAQYEHTRN-SRlgeglaggleglfnsnkftDTDLADVMLHSEINLPIDfivNQNLTLG 391
Cdd:PRK13513 279 DRNNYAITHNGYYDFGNSTS-YIQRDETRNpSR-------------------QMKSVDTIFNTQTSFLLD---DHTLSLG 335
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 392 TEWNQQRMKDstsftqtqqGGTIPGMSEDRSPYTSAEiFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQG 471
Cdd:PRK13513 336 GQYRYEELYD---------KGNQLPSASDLNKLTRWS-WALFAEDEWQMTNDFALTGGIRMDQDQNYGTHWTPRLYGVWH 405
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 472 LGDDFTLKMGIARAYKAPSLYQTNPNYLLYSKGqgcyASSDGVgcyMMGNDDLKAETSINKEIGLEW-KRDGWLAGVTWF 550
Cdd:PRK13513 406 LADQWTLKGGVSTGYRSPDLRQATDNWGQLTGG----GGLPAL---ILGNSDLKPEKSISQEIGILWdNQENLNASVTLF 478
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 551 RNDYRNKI-EAGYAPIGQTS-----TGKVTTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMlQSKNKE---TG 621
Cdd:PRK13513 479 NTDFKDKItEVRNCDTTNTDgqcvfNGINYDFISDRINVDKANMRGVEATFNWDINQAWSLATNYTFT-QSEQKSgafAG 557
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 622 DRLSIIPEYTLNSTLSWQVHQDVSLQSTFTWYGKQQPKKYNYKGQPVTGSekdevspYSIVGLSATWDVTKNVSLTGGVD 701
Cdd:PRK13513 558 QPLNQMPKHMANATLNWQTTEDFATWIRINYRGKTSEYLNRTSMGSGTPS-------YTFVDLGASYQLTKELRLMGGVY 630

                 ....*.
gi 515951937 702 NVFDKR 707
Cdd:PRK13513 631 NLLDKR 636
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
15-707 3.82e-81

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 273.04  E-value: 3.82e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  15 GIYGVALPVMADDNTASAQHEDTMVITA---AEQNLQAPG-VSTITADEIRKNPpARDVAEIIRTMPGVNLTGNStsgqr 90
Cdd:PRK13484  10 GIAVMCSAVISSGYASSDKKEDTLVVTAsgfTQQLRNAPAsVSVITSEQLQKKP-VSDLVDAVKDVEGISITGGN----- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  91 gNNRQIDIRGMGPENTLILIDGKPVTSRNSIRLGWRGErdtrgDTGWVPP-EMIERIEVIRGPAAARYGNGAAGGVVNII 169
Cdd:PRK13484  84 -EKPDISIRGLSGDYTLILVDGRRQSGRESRPNGSGGF-----EAGFIPPvEAIERIEVIRGPMSSLYGSDAIGGVINII 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 170 TKKFDDQ-WHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGD-FSFRMYGNLDKTQADAwdINQGHQSDrtgayadtlpa 247
Cdd:PRK13484 158 TKPVNNQtWDGVLGLGGIIQEHGKFGNSTTNDFYLSGPLIKDkLGLQLYGGMNYRKEDS--ISQGTPAK----------- 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 248 gregvENKDINGVVRWDFAPMQSLEFEAGysrQNNLYAGDTQNTNND--NSSSGLVKKNYGKETNRiYRQNFAVTWNGGW 325
Cdd:PRK13484 225 -----DNKNITATLQFTPTESQKFVFEYG---KNNQVHTLTPGESLDawTMRGNLKQPNSKRETHN-SRSHWVAAWNAQG 295
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 326 DngITTSNWAQY-EHTRNSRLGEGLaggleglfnsNKFTDTDLADVMLHSEI-NLPID-----FIVNQNLTLGTEWNQQR 398
Cdd:PRK13484 296 E--ILHPEIAVYqEKVIREVKSGKK----------DKYNHWDLNYESRKPEItNTIIDakvtaFLPENVLTIGGQFQHAE 363
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 399 MKDSTSFtqtqqggtipGMSEDRSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTL 478
Cdd:PRK13484 364 LRDDSAT----------GKKTTETQSVSIKQKAVFIENEYAATDSLALTGGLRLDNHEIYGSYWNPRLYAVYNLTDNLTL 433
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 479 KMGIARAYKAPSLYQTNPNYllyskgqgcYASSDGVGCYMMGNDDLKAETSINKEIGLEWKR-DGWLAGVTWFRNDYRNK 557
Cdd:PRK13484 434 KGGIAKAFRAPSIREVSPGF---------GTLTQGGASIMYGNRDLKPETSVTEEIGIIYSNdSGFSASATLFNTDFKNK 504
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 558 IEAGYAPIGQTSTGkvtTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYmLQSKNKETGDRLS----------II 627
Cdd:PRK13484 505 LTSYDIGTKDPVTG---LNTFIYDNVGEANIRGVELATQIPVYDKWHVSANYTF-TDSRRKSDDESLNgkslkgepleRT 580
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 628 PEYTLNSTLSWQVHQDVSLQSTFTWYGKQ--QPKKYNYKGQPVTgsekdevSPYSIVGLSATWDVTKNVSLTGGVDNVFD 705
Cdd:PRK13484 581 PRHAANAKLEWDYTQDITFYSSLNYTGKQiwAAQRNGAKVPRVR-------NGFTSMDIGLNYQILPDTLINFAVLNVTD 653

                 ..
gi 515951937 706 KR 707
Cdd:PRK13484 654 RK 655
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
36-721 1.22e-76

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 259.76  E-value: 1.22e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  36 DTMVITA---AEQNLQAPG-VSTITADEIRKNPpARDVAEIIRTMPGVNLTGNStsgqrGNNRQIDIRGMG--PENTLIL 109
Cdd:COG1629    2 EEVVVTAtrtDESLQDVPGsVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAG-----GGAGQISIRGFGggGNRVLVL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 110 IDGKPVTSRNSIRLGWRgerdtrgdtgWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNApe 189
Cdd:COG1629   76 VDGVPLNDPSGGDGGLS----------YIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGS-- 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 190 hkdeGSTKRTNFSLSGPlGGDFSFRMYGNldKTQADAWDINQghqsdrtgayadtlpagreGVENKDINGVVRWDFAPMQ 269
Cdd:COG1629  144 ----YGTYRASLSLSGG-NGKLAYRLSAS--YRDSDGYRDNS-------------------DSDRYNLRAKLGYQLGDDT 197
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 270 SLEFEAGYSRQNNLYAGDTQNTN---NDNSSSGLVKKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLG 346
Cdd:COG1629  198 RLTLSASYSDSDQDSPGYLTLAAlrpRGAMDDGTNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSD 277
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 347 EGLAGGLEGLFNSNKFTDTDLAdvmLHSEINLPIDFIVNQNLTLGTEWNQQRMkDSTSFTQTQQGGTIPGMSEDRSPYTS 426
Cdd:COG1629  278 FTPTPADGGTLEQTDFDNRTYG---LELRLTYDLGFGGKHTLLVGLDYQRQDL-DGSGYPLDLGSGSLPTLTSGADDDGT 353
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 427 AEIFSLFAENNMELTDSTMLTPALRFDHHTIVG----------------NNWSPSLNLSQGLGDDFTLKMGIARAYKAPS 490
Cdd:COG1629  354 TTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVddtvtgtdsasgsrsySAFSPSLGLTYQLSPNLSLYASYSRGFRAPT 433
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 491 LYQTNPNyllyskgqgcyassdGVGCYMMGNDDLKAETSINKEIGL--EWKRDGWLAGVTWFRNDYRNKIEAGYAPigqT 568
Cdd:COG1629  434 FGELYAN---------------GTDPYSVGNPDLKPETSTNYELGLryRLLDGRLSLSLALFYSDVDNEILSVPLP---N 495
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 569 STGKVTtdiyQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMlQSKNKE--------TGDRLSIIPEYTLNSTLSWQV 640
Cdd:COG1629  496 DSGFST----YYTNAGKARSYGVELELSYQLTPGLSLNASYSYT-DAKFDDdtdgsadlDGNRLPGVPPLTANLGLTYEF 570
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 641 HQDVSLQSTFTWYGKQQPKKYNYKGQPvtgsekdevSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAQTTGNT 720
Cdd:COG1629  571 PGGWSLGLGVRYVGDRYLDDANTQGAP---------GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVR 641

                 .
gi 515951937 721 T 721
Cdd:COG1629  642 G 642
OM_channels cd01345
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
462-746 2.14e-73

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


Pssm-ID: 238655 [Multi-domain]  Cd Length: 253  Bit Score: 238.87  E-value: 2.14e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 462 WSPSLNLSQGLG----DDFTLKMGIARAYKAPSLYQTNPNyllyskgqgcyassdgvgcymmgNDDLKAETSINKEIGLE 537
Cdd:cd01345    7 FNPVLNIRQGLGqtpdDDLTLK*GYARANKAPSLYQTNPG-----------------------NDDAKAETSDGKEIGLE 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 538 WKR-DGWLAGVTWFRNDYRNKIEAGYAPIGQTSTGkvtTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSK 616
Cdd:cd01345   64 FKRdGGWLAGVTYARNDYTNKIEAGYVAVGQNAVG---TDLYQWDNVPKAVVEGLEGSLNVPVSETV*WTNNYTY*LKSE 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 617 NKetGDRLSIIPEYTLNSTLSWQVHQDVSLQSTFTWYGKQQPKKYNykgqpvtgsekdEVSPYSIVGLSATWDVTKNVSL 696
Cdd:cd01345  141 NK--TTRLSIIPEYTLNVTLSWQAREDLS*QVTYTWYKKQQPKKYK------------EIDPYSIVGLSATWDVTKNVSL 206
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 515951937 697 TGGVDNVFDKRQWRAGNAQTTGNtttGAYMYGAGAYTYNEPGRTWYMSVN 746
Cdd:cd01345  207 TGGYDNLFDKRLWRAGNAQTTGD---ANYIAGAGAYTYNEPGDTWY*GVN 253
PRK13486 PRK13486
TonB-dependent receptor;
19-749 1.39e-67

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 236.46  E-value: 1.39e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  19 VALPVMADDNTASAQHEDTMVITAA--EQNLQ--APGVSTITADEIRKNPpARDVAEIIRTMPGVNLtgNSTSGQRGNnR 94
Cdd:PRK13486   9 VVIPCLGFSASSIAAAEDVMIVSASgyEKKLTnaAASVSVISQEELQSSQ-YHDLAEALRSVEGVDV--ESGTGKTGG-L 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  95 QIDIRGMGPENTLILIDGkpvtsrnsIRLGWRGERDTRG----DTGWVPP-EMIERIEVIRGPAAARYGNGAAGGVVNII 169
Cdd:PRK13486  85 EISIRGMPASYTLILIDG--------VRQGGSSDVTPNGfsamNTGFMPPlAAIERIEVIRGPMSTLYGSDAMGGVVNII 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 170 TKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPL-GGDFSFRMYGNLDKTQADAwdinqghQSDRTGAYADTLPAG 248
Cdd:PRK13486 157 TRKNADKWLSSVNAGLNLQESNKWGNSSQFNFWSSGPLvDDSVSLQVRGSTQQRQGSS-------VTSLSDTAATRIPYP 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 249 REGvENKDINGVVRWDFAPMQSLEFEAGYSRQnnlyagdtqntNNDNSSSGLVKKNYGKETNRIYRQNfavTWNGGWDNG 328
Cdd:PRK13486 230 TES-QNYNLGARLDWKASEQDVLWFDMDTTRQ-----------RYDNRDGQLGSLTGGYDRTLRYERN---KISAGYDHT 294
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 329 ITTSNWAQY----EHTRNSRLGEGLAGGLEGLFNSNKFTDTDLADVMLHSEINLPIDfiVNQNLTLGTEWNQQRMKDSTS 404
Cdd:PRK13486 295 FTFGTWKSYlnwnETENKGRELVRSVLKRDKWGLAGQPRELKESNLILNSLLLTPLG--ESHLVTVGGEFQSSSMKDGVV 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 405 FTQTqqGGTIPGMSedrspytsaeiFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTLKMGIAR 484
Cdd:PRK13486 373 LAST--GETFRQKS-----------WSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTT 439
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 485 AYKAPSLYQTNpNYLLYSKGQGcyassdgvGCYMMGNDDLKAETSINKEIGLEWKR-DGWLAGVTWFRNDYRNKIeAGYA 563
Cdd:PRK13486 440 GYKAPRMGQLH-KGISGVSGQG--------KTNLLGNPDLKPEESVSYEAGVYYDNpAGLNANVTGFMTDFSNKI-VSYS 509
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 564 PIGQTSTgkvttdiyqWENVPKAVVEGLEGSLNVPV-SDTINWTNNITYMlQSKNKE---TGDRLSIIPEYTLNSTLSWQ 639
Cdd:PRK13486 510 INDNTNS---------YVNSGKARLHGVEFAGTLPLwSEDVTLSLNYTWT-RSEQRDgdnKGAPLSYTPEHMVNAKLNWQ 579
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 640 VHQDVSLQSTFTWYGKQQPKKYNYKG-----QPVTGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDK-----RQW 709
Cdd:PRK13486 580 ITEEVASWLGARYRGKTPRFTQNYSSlsavqKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKdysdvSLY 659
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|.
gi 515951937 710 RAGnaqtTGNTTTGAYMYGAGAYT-YNEPGRTWYMSVNTRF 749
Cdd:PRK13486 660 SAG----KSTLYAGDYFQTGSSTTgYVIPERNYWMSLNYQF 696
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
36-749 1.78e-59

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 214.20  E-value: 1.78e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   36 DTMVITAAEQNL--------QAPGVSTITADEIRKNPPaRDVAEIIRTMPGVNLTGnstsGQRGNNRQIDIRGMGPENTL 107
Cdd:TIGR01786   1 DTITVTATRTADpqrrdlsvTPASVSVISREQLKSQQV-RNLRDLLRYEPGVSVVE----GGRGGSQGINIRGLDKNRVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  108 ILIDGkpvtsrnsIRLGWR--GERDTRGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDD------QWHG 179
Cdd:TIGR01786  76 VLVDG--------IRQNTSygGQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADllkpgkDLGG 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  180 -SWNTYlnapehkdegSTKRTNFSLSGPLGGdfsfrMYGNLDK-TQADAWDINQGHQSDRTGAYADTLPAGREGVENKDI 257
Cdd:TIGR01786 148 lSKLGY----------SSANNRFTQSVAAAG-----RNDDVDAlVQATYRRGHELKNGNKANIGNESKRSKPNPSDYKSQ 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  258 NGVVR--WDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNSSSGLVKKNYGKETN-RIYRQNFAVT--WNG--GWDNgiT 330
Cdd:TIGR01786 213 SFLAKlgWQLNDAHRLGLSLEYTQTDYDEPEMTNTSYLTKPLGAPLLSSTVVLGDsKTRDRRTGLDyeLNPdnSWLD--T 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  331 TSNWAQYEHTRNSRLGEGLAGGLEGLFNSNKFTDTDLADVMLHSEINLPIDFIV-NQNLTLGTEWNQQRMKDSTSFTQTQ 409
Cdd:TIGR01786 291 VKLALDKQYIQLYNYLNATSASDYPGVDKNGRYKDKYDYYTLGFDTNNKIEFSVhSLSLTYGLDRFKDKVSTGDSRRNLP 370
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  410 QGG-TIPGMSEDRSPYTSaEIFSLFAENNMELTDSTMLTPALRFDHHTIVG---------------NNWSPSLNLSQGLG 473
Cdd:TIGR01786 371 TAAyNLYGYEGENRPVKG-SNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPkadeskdygaisktySRWSPSLGLTYKPT 449
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  474 DDFTLKMGIARAYKAPSLYQtnpnylLYskgqGCYASSDGVGCYMMGNDDLKAETSINKEIGLEWKRDgWLAG-VTWFRN 552
Cdd:TIGR01786 450 PWLTLYYSYSQGFRAPSFDE------LY----GTGAHPGGGPYTFLPNPNLKPETSKNWEIGINLHFD-QLDFkVSYFRN 518
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  553 DYRNKIEAGY---APIGQTSTGKVTtdIYQWENVPKAVVEGLE--GSLNV----PVSDTINWTNNITYMlQSKNKETGDR 623
Cdd:TIGR01786 519 DYKDFIDLGIgvtAKGNMAQVGSNT--ITNYVNIDNARIRGIElsGRYDLgsffSGPDGWTTTLKYGYT-KGKDSDTNPW 595
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  624 LSIIPEYTLNSTLSWQVHQDV-SLQSTFTWYGKQ--QPKKYNYKGQPVTGSEKDEVSP-YSIVGLSATWDVTKNVSLTGG 699
Cdd:TIGR01786 596 LNAITPLKVVLGLGYDHPDEKwGVGLTLTFSGAKdaVDAYATYYENGEAAKAGPLRTPsYTVVDLYGYYKPNKNLTLRFG 675
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|
gi 515951937  700 VDNVFDKRQWRAgnaqttgnttTGAYMYGAGAYTYNEPGRTWYMSVNTRF 749
Cdd:TIGR01786 676 VYNLLDRKYTTW----------ESARQAGPLATGYTAPGRNYKASVEYKF 715
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
36-727 2.16e-58

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 209.94  E-value: 2.16e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   36 DTMVITAA--EQNLQ--APGVSTITADEIRKNPPaRDVAEIIRTMPGVNLTGnstsGQRGNNRQIDIRGMGPENTLILID 111
Cdd:TIGR01785   2 DTVTVTATrtRQVLSeaPASVSVISGEQIESKQA-NNLADALNTVPGVDVTG----GGRPPGQSINIRGLQDNRVLVVVD 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  112 GkpvtsrnsIRLGWRGERDTRGDTgWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNApehk 191
Cdd:TIGR01785  77 G--------ARQNYQRGGAHNGSL-FVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLA---- 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  192 degSTKRTNFSLSGPLGGDFSFRMYGNLDK-TQADAWDINQGHQSDRTgayadtlPAGREGVENKDINGVVRWDFAPMQS 270
Cdd:TIGR01785 144 ---KLSYGSNNNSFGGSVAVAGRLDDNLDAlVAATYRDGGNYRNGNKE-------EATNSAYVQKNLLAKLGWQLDDAQR 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  271 LEFEAGYSR-QNNLYAGDTQNTNNDNSSSGLVKKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEH-TRNSRlgeg 348
Cdd:TIGR01785 214 LEFSYFTTEgSLDEAQNSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPEDNPWLDATASLYYNRTENDnDRSAR---- 289
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  349 laggleGLFNSNKFTDTDL-ADVMLHSEINLpidfIVNQNLTLGTEWNQQRMKdSTSFTQTQQGGTIPgmsedrSPYTSA 427
Cdd:TIGR01785 290 ------GVGREEGYQYTTYgATLQNTSRFDV----ASWSTLTYGVDWMKDKRR-TESFDPNSVTTIVP------NPPSAK 352
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  428 E-IFSLFAENNMELTDSTM-LTPALRFDHHTIVGNN-------------WSPSLNLSQGLGDDFTLKMGIARAYKAPSLY 492
Cdd:TIGR01785 353 EyFFGLFLQDNIPLLDDRLtLSAGLRYDHYKLSPKTtadteavdrsysrWSPSLGLSYKPVDWLTLYASYSQGFRAPSID 432
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  493 QTNPNYllyskgqgcYASSDGVGCYMMGNDDLKAETSINKEIGLEWKRDGWLAG-------VTWFRNDYRNKIEAGYAPI 565
Cdd:TIGR01785 433 ELYGTG---------DHPGTPGGYTFAPNPNLKPETSKTWELGANLSFDNLLLDndqlqfkVAYFYNDVKDFIDLTIGVT 503
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  566 GQTSTGKVTtdIYQWENVPKAVVEGLEGSLNVpvsDTINWTNNITYM-LQSKNKETGDRLSIIPEYTLNSTLSWQVHQ-D 643
Cdd:TIGR01785 504 DNVTAGMNN--ITQYVNIDGARIRGIEASASY---DAGLWATGLSYGyTIGKDQNTNQWLSNIPPLKLVVTVGYRFPDrR 578
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  644 VSLQSTFTWYGKQQPkkyNYKGQPVTGSEKDEVSPYSIVGLSATWDVT--KNVSLTGGVDNVFDKRQWRAGN--AQTTGN 719
Cdd:TIGR01785 579 LDLGAKAAYYERQSE---SPTTEDVAANGLLTTPGYTVVDLYATYQPNavKGLTVRFGVNNLTDRKYTPAQSvpGAGPGR 655

                  ....*...
gi 515951937  720 TTTGAYMY 727
Cdd:TIGR01785 656 NFKGSVKY 663
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
20-749 3.28e-58

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 209.78  E-value: 3.28e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  20 ALPVMADDNTASAQHE----DTMVITA---AEQNLQA-PG-VSTITADEIRkNPPARDVAEIIRTMPGVNLTGNSTSGQR 90
Cdd:COG4772    4 ALAAALLLAAAAAAEAattlETVVVTGsraAEARLKDvPGsVSVVDREELE-NQAATSLREVLRRVPGVNVQEEDGFGLR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  91 GNnrqIDIRGMGPE---NTLILIDGKPVTSrnsirlgwrgerDTRGDTGWV---PPEMIERIEVIRGPAAARYGNGAAGG 164
Cdd:COG4772   83 PN---IGIRGLGPRrsrGITLLEDGIPIAP------------APYGDPAAYyfpDLERMERIEVLRGAAALRYGPQTVGG 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 165 VVNIITKKFDDQWHGSWNTYLnapehkdeGS--TKRTNFSLSGPLGgdfSFRMYGNLDKTQADAWDINQGHQSDrtgaya 242
Cdd:COG4772  148 AINFVTRTIPTAFGGELRVTG--------GSfgYRRTHASVGGTVG---NFGYLVEYSRKRGDGFRDNSGFDIN------ 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 243 dtlpagregvenkDINGVVRWDFAPMQSLEFEAGYSRQN-NLYAGDTQNTNNDNSSSGLVKKNYGKetnrIYRQNFAVTW 321
Cdd:COG4772  211 -------------DFNAKLGYRLSDRQELTLKFQYYDEDaNTPGGLTDAQFDADPRQSYRPADQFD----TRRTQLSLRY 273
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 322 NGGWDNG--ITTSNWAqYEHTRNS--RLGEGLAGGLEGLFNSNKFTDTDL-ADVMLHSEINLpidFIVNQNLTLGTEWNQ 396
Cdd:COG4772  274 EHQLSDNttLTTTAYY-NDFSRNWyiRQNTADPNTPGLGLRGNPRGYRSYgIEPRLTHRFEL---GGVPHTLEVGLRYHR 349
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 397 QRMKDSTSFTQTQQGGTipGMSEDRSPYTSAEIFSLFAENNMELTDSTMLTPALRFDH-------HTIVGNN-------- 461
Cdd:COG4772  350 EEEDRKQYVNTYGQGRS--GAGLRRDRRFSADALAAYAQNRFELTGRLTLTPGLRYEHirrdrtdRYSTRTGgddsgsns 427
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 462 ---WSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQtnpnyLLYSKGqgcyassdgvgcymmGNDDLKAETSINKEIGLEW 538
Cdd:COG4772  428 yseFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGD-----LAYGNG---------------GNPDLKPEKSWNYELGTRG 487
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 539 KRDGWLAG-VTWFRNDYRNKIEAGYAPIGQTSTgkvttdiyqWENVPKAVVEGLEGSLNV----PVSDTINWTNNITYmL 613
Cdd:COG4772  488 RIGNGLSAeVALFYIDYDNELGSCSAAGGDRST---------FTNAGETRHQGLELALDYdllkGGGLGLPLFAAYTY-T 557
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 614 QSKNKET------GDRLSIIPEYTLNSTLSWQvHQDVSLQSTFTWYGKQqpkkYNYKGQPVTGSEKDEVSPYSIVGLSAT 687
Cdd:COG4772  558 DAEFTSDfgpvfaGNRLPYVPRHQLTAGLGYE-HGGWTANLNGRYVSEQ----FTDAANTVADGSFGKIPSYTVLDLSAS 632
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515951937 688 WDVTKNVSLTGGVDNVFDKRQWragnaqttgntTTGAYMYGAGAYTynEPGRTWYMSVNTRF 749
Cdd:COG4772  633 YDFGKNLSLFAGVNNLFDKRYI-----------ASRAPNYAAGIRP--GPPRTVYAGLRLKF 681
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
52-749 7.33e-47

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 177.39  E-value: 7.33e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  52 VSTITADEIR-KNppARDVAEIIRTMPGVNLTGNSTSGQRgnnrQIDIRGMGPENtlILIDGKPVTSRNSIRlgwrgerd 130
Cdd:COG4773   69 VSVVTRQLIEdQG--ATTLDDALRNVPGVTVSSYDGGGRD----SFSIRGFSIDN--YLRDGLPLGGFGGGQ-------- 132
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 131 trgdtgwVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWH-------GSWNTYlnapehkdegstkRTNFSL 203
Cdd:COG4773  133 -------PDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAEPQgevslsaGSWDTY-------------RATADV 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 204 SGPLGGDFSFRMYGNLDKTQADAWdinQGHQSDRTGAyadtlpagregvenkdINGVVRWDFAPmqSLEFEAGYSRQNNL 283
Cdd:COG4773  193 GGPLNEDGTLRYRLNAAYEDGDSF---RDGVDNRRTL----------------IAPSLDWDLTD--DTTLTLGAEYQDDD 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 284 YAGDTQNTNNDNSSSGL-VKKNYGKETNRI--YRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLE------ 354
Cdd:COG4773  252 STGDRGFLPLDGTLLDLpRSTNLGEPWDYYdtETTTLFAELEHRFNDDWSLRANARYSDSDRDGRSAYAYGAPDaatgtl 331
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 355 --GLFNSNKFTDTDLADVMLHSEINLpidFIVNQNLTLGTEWNQQRMKDSTSFTQTQ-----QGGTIPGMSEDRSPYTS- 426
Cdd:COG4773  332 trYASARDGDSRSDSLDANLNGKFET---GGLEHTLLVGADYSRYDSDSDSATAGTIniynpVYGNLPEPDFDASDTDTt 408
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 427 AEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGlGDDFTLKMGIaraykapsLYQTNPN---YLLYSK 503
Cdd:COG4773  409 TRQTGLYAQDQISLTDRLSLLLGGRYDWYETDSTNRLGGSTTSYD-DSAFTPRAGL--------VYDLTPGlslYASYSE 479
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 504 G--QGCYASSDGvgcymmgnDDLKAETSINKEIGL--EWKRDGWLAGVTWFRNDYRN-KIEAGYAPIGQTSTGKVTTdiy 578
Cdd:COG4773  480 SfePQSGADNNG--------NPLDPETGKQYEAGVkgELFDGRLNATLAVFDITQKNvATTDPDNPNFYVQVGEVRS--- 548
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 579 qwenvpkavvEGLEGSLNVPVSDTINWTNNITYM----LQSKNKETGDRLSIIPEYTLNSTLSWQVHQ----DVSLQSTF 650
Cdd:COG4773  549 ----------RGVELELSGELTPGLNLIAGYTYTdakiTKDADALEGKRLTNVPRHTASLWTTYRFPSgalkGLGLGGGV 618
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 651 TWYGKQQpkkynykgqpVTGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWragnaqtTGNTTTGAYMYGAg 730
Cdd:COG4773  619 RYVGERY----------GDAANTFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYY-------ASSGSRGYVYYGA- 680
                        730
                 ....*....|....*....
gi 515951937 731 aytynepGRTWYMSVNTRF 749
Cdd:COG4773  681 -------PRNVRLSLSYKF 692
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
276-748 6.04e-46

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 171.11  E-value: 6.04e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  276 GYSRQNNLYAGDTQNTNNDNSSSGLVKKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEG 355
Cdd:pfam00593  26 DGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAG 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  356 LFNSNKFTDTDLADVmlhseINLPIDFIVNQNLTLGTEWNQQRMKDSTSFTQTQQGGTIPGMSEDRSPYTSAEIFSLFAE 435
Cdd:pfam00593 106 DYLSDDRLYGLYGLD-----GDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQ 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  436 NNMELTDSTMLTPALRFDHHTIVGNN--------------WSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYlly 501
Cdd:pfam00593 181 DNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSG--- 257
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  502 skgqgcyaSSDGVGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRNDYRNKIEAgyapigQTSTGKVTTDIYQWE 581
Cdd:pfam00593 258 --------SGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITS------DPDGPGLGGTVYTYT 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  582 NVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKE---TGDRLSIIPEYTLNSTLSWQVHQD---VSLQSTFTWYGK 655
Cdd:pfam00593 324 NVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADaddTGNPLPNVPRHTANLGLTYDFPLGgwgARLGARYVGSGE 403
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  656 QQPKKYNykgqpvtgsEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAQttgntttgaymyGAGAYTYN 735
Cdd:pfam00593 404 RRYGDAA---------NTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSG------------GGNLGGYP 462
                         490
                  ....*....|...
gi 515951937  736 EPGRTWYMSVNTR 748
Cdd:pfam00593 463 GPGRTFYLGLSYK 475
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
52-749 3.98e-45

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 171.60  E-value: 3.98e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  52 VSTITADEIRkNPPARDVAEIIRTMPGVnltgnSTSGQRGNNR-QIDIRGMGPENTlILIDGKPVTSRNSIrlgwrgerd 130
Cdd:COG4774   13 VTVVTRELIE-DQGATSLADALRNVPGV-----TFGAGEGGNGdSFSIRGFSASGD-IYVDGLRDPGQYRR--------- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 131 trgdtgwvPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLnapehkDEGSTKRTNFSLSGPLGGD 210
Cdd:COG4774   77 --------DTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVTLTY------GSDGQRRATLDVNGPLGDD 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 211 FSFRMygNLDKTQADAWdinqghqsdrtgayadtlpagREGVENKD--INGVVRWDFAPMQSLEFEAGYSRQNNLYAGDT 288
Cdd:COG4774  143 LAYRL--NGMYRDSDSY---------------------RDGVDNDRwgIAPSLTWRLGDRTRLTLDYEYQDDDRTPDYGV 199
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 289 QNTNNDNSSSGLVKKNYGKETNRIYRQNFAVTWNGGWD--NGITTSNWAQYEHTRNSRLGEGLAGGLEGLFNSNKFTDTD 366
Cdd:COG4774  200 PAVANGRPVDVDRSTFYGQPDDYSDSETDSATLRLEHDfnDNWTLRNALRYSDYDRDYRNTYPTGGNATGTVTRSAYRRD 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 367 LADVMLHSEINLPIDF---IVNQNLTLGTEWNQQRMkDSTSFTQTQQGGTI---------PGMSEDRSPY---TSAEIFS 431
Cdd:COG4774  280 QDNDTLSNQTDLTGKFdtgGVKHTLLAGVEYSREDS-DNARYSGGGTAPTVnlynpvygaPVTGPTLGGAdndSRTDTTG 358
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 432 LFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTLKMGIaraykapsLYQTNPN---YLLYSKGqgcY 508
Cdd:COG4774  359 LYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTTGATTSSYDDSAFSPRAGL--------VYKPTPNlslYASYSTS---F 427
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 509 ASSDGVGCYMMGNDDLKAETSINKEIGL--EWKRDGWLAGVTWFRNDYRNkieagyapigQTSTGKVTTDIYQweNVPKA 586
Cdd:COG4774  428 NPGGGAPSLSNAGQALDPEKSRQYEVGVkwDLLDGRLSLTAALFRIEKTN----------VRTTDPANPGVYV--QTGEQ 495
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 587 VVEGLEGSLNVPVSDTINWTNNITYMlQSKNKET------GDRLSIIPEYTLNSTLSWQVH-QDVSLQSTFTWYGKQqpk 659
Cdd:COG4774  496 RSRGVELEATGELTPGWSVLAGYTYL-DAEITKSanaanvGNRLPNVPRHSASLWTTYDLPlPGLTLGGGVRYVGSR--- 571
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 660 kynYKGQPVTgsekDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAqttgnttTGAYMYGAgaytynepGR 739
Cdd:COG4774  572 ---YADAANT----VKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASAYG-------SGYVTPGA--------PR 629
                        730
                 ....*....|
gi 515951937 740 TWYMSVNTRF 749
Cdd:COG4774  630 TVLLSASYRF 639
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
32-749 3.10e-37

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 148.09  E-value: 3.10e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   32 AQHEDTMVITA------AEQNLQApgVSTITADEIRKNPpARDVAEIIRTMPGVNLTGNstsGQRGNNRQIDIRGMGPEN 105
Cdd:TIGR01779  25 AQPLDTVVVTAnrfaqtASQTLAP--VTIITRQDIERTQ-AKSLPELLRRLPGVSIAQN---GGRGQNTSLFLRGTESDH 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  106 TLILIDGkpvtsrnsIRLGwrgeRDTRGDTGW--VPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQwhgsWNT 183
Cdd:TIGR01779  99 VLVLIDG--------IRFG----SAAAGAADFqqLPVELVERIEYVRGPRSSLYGSEAIGGVINIITRRRSGG----QGT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  184 YLNApehkDEGSTKRTNFSLSGPLGGDFSFRMYGNLDKTQADAWDINQGhqsdrTGAYADtlpAGREGVENKDINGVVRW 263
Cdd:TIGR01779 163 TLSA----GLGSLDYQEYSIASGVAIGENGWYSVALGTESTKGINVRPG-----GPGVYD---PDRDGFRSDSLLLGGGH 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  264 dfapmqslEFEAGYSRQNNLYAGDTQNtNNDNSSSGlvkkNYGKETNRIYRQNF--AVTWNGGWDNGITTSnwaQYEHTR 341
Cdd:TIGR01779 231 --------RFDESWSLFVNALRYENRN-DYDNYSFG----TRLYKEAEKGDQSFtgGRQRQSERDVSELTL---STGKSK 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  342 NsrlgeglaggLEGLFNSNKFTDTdlADVMLHSEINLPIDFIVNQN--LTLGTEWNQQRMKDSTSFTQTQQGGTipgmse 419
Cdd:TIGR01779 295 D----------WDYAYSKGRYSST--SDTREQRNIQWQNDLLVGDGwvLAGGVDWQKDSIISSTADKEDDRSNT------ 356
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  420 drspytsaeifSLFAENNMELTDSTmLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQT-NPNY 498
Cdd:TIGR01779 357 -----------AAFAQVLQQWGQQL-LEASLRRDDNQQFGSHTTGSIAWGYQFIEELRFTASYGTAFKAPNLNQLyYPSY 424
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  499 llyskgqgcyassdgvgcymmGNDDLKAETSINKEIGLEwkrdGWLAGVTWFRNDYRNKIE--AGYAPIGQTstgkvttd 576
Cdd:TIGR01779 425 ---------------------GNPNLQPETSKSAELGFY----GLFSGGKWSISGYRTKINdlIDYDSHPKG-------- 471
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  577 iyQWENVPKAVVEGLEGSLNvpvSDTINWTNNITY-MLQSKNKETGDRLSIIPEYTLNSTLSWQVhQDVSLQSTFTWYGK 655
Cdd:TIGR01779 472 --YPNNIGEARIKGVEATAE---FATGGWTHQLSVdLLDAQNVNTGNTLPRRARQMYKWNADRAF-EQFDWGASYQYVGK 545
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  656 QQPKKYN-YKGQPVTgsekdeVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKrqwragNAQTtgntttgaymygagAYTY 734
Cdd:TIGR01779 546 RYDDDYNtYPTQNVR------LGGYSLLDLRVSYYVTDSWTVQGRIANLFDK------DYET--------------AYGY 599
                         730
                  ....*....|....*
gi 515951937  735 NEPGRTWYMSVNTRF 749
Cdd:TIGR01779 600 PQAGRAYYLSIRYQF 614
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
38-343 4.53e-36

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 137.31  E-value: 4.53e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  38 MVITA--AEQNLQAPG--VSTITADEIRKNPpARDVAEIIRTMPGVNLtgnSTSGQRGNNRQIDIRGMGPENTLILIDGK 113
Cdd:COG4206    1 VVVTAtrLEQSKSDLTgsVTVIDAEELERSG-ATSLADALRRVPGVQV---SSSGGPGSAASISIRGLGSNQTLVLIDGV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 114 PVtsrNSIRLGWRgerdtrgDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNapehkdE 193
Cdd:COG4206   77 PL---NDPSLGGV-------DLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYG------S 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 194 GSTKRTNFSLSGPLGGdfsFRMYGNLDKTQADAWDinqghqsdrtgaYADTLPAGREGVENKDINGVVRWDFAPMQSLEF 273
Cdd:COG4206  141 FGTRRLSASLSGGAGK---FSYSLSASYRRSDGYR------------YNDPDLRNNDGYENTSLNARLGYKLGDNGSLSL 205
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 274 EAGYSRQNNLYAGDTQNTNNDNSSSGLVKKNYGKETNRiyRQNFAVTWNGGWDNGITTSNWAQYEHTRNS 343
Cdd:COG4206  206 SGGYSDSERGYPGAVGSDRNLRLSLSLEYKLSDGWSLL--LLAYYYYDRDYEDGGGDSAGTSNTDGARAG 273
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
1-744 1.01e-33

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 137.43  E-value: 1.01e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   1 MNKKIHSLAllvnlgiygvALPVMADDNTASAQHEDTMVITAaeQNLQAPgVSTI-------TADEIRKnPPARDVAEII 73
Cdd:PRK10641   1 MIKKASLLT----------ALSVTAFSGWAQDTSPDTLVVTA--NRFQQP-VSTVlapttvvTRDDIDR-WQSKSVNDVL 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  74 RTMPGVNLTGNSTSGQRGNnrqIDIRGMGPENTLILIDGKPVTsrnsiRLGWRGErdtrGDTGWVPPEMIERIEVIRGPA 153
Cdd:PRK10641  67 RRLPGVDIAQNGGLGQLSS---LFIRGTNSSHVLVLIDGVRLN-----QAGISGS----ADLSQIPISLVQRIEYIRGPR 134
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 154 AARYGNGAAGGVVNIITKKFDDQwhgswnTYLNApehkDEGSTKRTNF--SLSGPLGGDFSFRMYGNLDKT-----QADA 226
Cdd:PRK10641 135 SAVYGSDAIGGVVNIITTRDKPG------TTLSA----GWGSNGYQNYdgSTQQQLGDNTRVTLAGDYTYTkgfdvVAYG 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 227 wDINQGHQSDRTGAYADTLPAGREGVENKDINGVVRwdfapmqslefeaGYsrqnnlyaGDTQNTNNDNSSSGlvkKNYG 306
Cdd:PRK10641 205 -NTGTQAQPDRDGFMSKTLWGGLEHQFNDQWSGFVR-------------GY--------GYDNRTDYDAYYSP---GSPL 259
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 307 KETNRIYRQnfavTWNGG--WDNGITTSNW-AQYEHTRNSRLGEGLaggleglfnsNKFTDTDLADVMLHSEINLPIDFI 383
Cdd:PRK10641 260 IDTRQLYSQ----SWDAGlrYNGGIYSSQLiASYSHSKDYNYDPHY----------GRYDSSATLDDMKQYNVQWGNTVQ 325
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 384 VNQ-NLTLGTEWNQQRMKDSTSFTQTQQGGTIPGMsedrspYTSAeifslfaennMELTDSTMLTPALRFDHHTIVGnnW 462
Cdd:PRK10641 326 VGHgNISAGVDWQKQTTTPGTGYVPDGYDQRNTGI------YLTG----------QQQIGDVTLEGAARSDDNSQFG--W 387
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 463 SPSLNLSQG--LGDDFTLKMGIARAYKAPSLYQtnpnylLYSKGqgcyassdgvgcymmGNDDLKAETSINKEIGLEwkr 540
Cdd:PRK10641 388 HGTWQTSAGweFIDGYRFIASYGTAFKAPNLGQ------LYGFY---------------GNPNLKPEESKQWEGGFE--- 443
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 541 dGWLAGVTWFRNDYRNKIE--AGYAPIGqtstgkvttdiYQWENVPKAVVEGLEGSLNVpvsDTINWTNNITY-MLQSKN 617
Cdd:PRK10641 444 -GLTGPVNWRLSGYRNDIDnlIDYDDHT-----------LKYYNVGKATIKGVEWTGNF---DTGPLTHQVTLdYVDPRN 508
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 618 KETGDRLSIIPEYTLNSTLSWQVHqDVSLQSTFTWYGKQQPKKYNykgqpVTGSEKDEVSPYSIVGLSATWDVTKNVSLT 697
Cdd:PRK10641 509 AITDEPLARRAKQQVKYQLDWQLY-DFDWGVTYQYLGTRYDKDYS-----TYPYQTVKLGGVSLWDLAVSYPVTSHLTVR 582
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|....*..
gi 515951937 698 GGVDNVFDKrqwragNAQTtgntttgaymygagAYTYNEPGRTWYMS 744
Cdd:PRK10641 583 GKIANLFDK------DYET--------------VYGYQTAGREYTLS 609
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
52-165 1.18e-28

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 110.44  E-value: 1.18e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   52 VSTITADEIRKNPpARDVAEIIRTMPGVNltgnSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNsirlgwrgerDT 131
Cdd:pfam07715   9 VSVVTAEDIEDQG-ATNLADALRGVPGVS----VSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGG----------GG 73
                          90       100       110
                  ....*....|....*....|....*....|....
gi 515951937  132 RGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGV 165
Cdd:pfam07715  74 SVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
52-749 1.50e-12

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 71.21  E-value: 1.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   52 VSTITADEIRKNPpARDVAEIIRTMPGVnltgnSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRlgwrgeRDT 131
Cdd:TIGR01782  27 VDVISAEDIGKLP-DVNVAEALQRVPGV-----SIERDQGEGRYVSVRGLGPSYNRTTLNGRTIASTDSGG------RAF 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  132 RGDTgwVPPEMIERIEVIRGPAAARYGnGAAGGVVNIITKK-FD-DQWHGSWNTYLNAPEH-KDEGSTKRTNFSLSGPLG 208
Cdd:TIGR01782  95 SLDL--LPSELVSGVEVYKTPTADMDE-GGIGGTVDLRTRSpFDyDGRTLSGSAQGGYNDLaGKDKPGPRGAASYSWTFG 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  209 -GDF---------------------SFRMYGNLDKTQADAWdINQGHQS-------DRTGA--------------YADTL 245
Cdd:TIGR01782 172 dGQFgvllsasyqkrdfaednveteNWGTYTSADGGAQGLY-FPRGVRYrsyrndrERKGVngslqwrpsdalelYLDTL 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  246 pAGREGVENKDINGVVRWDFAPMQ--------------------------------------------------SLEFEA 275
Cdd:TIGR01782 251 -YSKYDDDETRQQIEFRTLNGGSTvitsnqtatsgalvqgtvanlqilvearyneeketttsltlggewtgdrwTLDGDL 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  276 GYSR---------------QNNLYAGDTQNTNNDNSS---SGLVKKNYGKETN------RIYRQN-----FAVTWNGGWD 326
Cdd:TIGR01782 330 GYSKatrdrpdrvtrfftaPTPGYDFDYRGGPTLTLGtpaDGDDASNYTNPANgelrrtQISYQKaedseDAAQLDATFD 409
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  327 nGITTS-----NWAQYEHTRNSRlGEGLAGGLEGLFNSNKFTDTDLADVMLHSEINLPIDFIVNQNltLGTEWNQQRmKD 401
Cdd:TIGR01782 410 -GPFTSlkfgvRYRRRDKTNRGS-RYRRSIIGATGASGLAGVPSDLAGAGLDGGLGGPLTGWDPAD--LDAFLNAAR-GD 484
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  402 STSFTQTQQGGTIPGMsedrspYTSAE-IFSLFAENNMELTDSTMLTPALRFDH--HTIVG------------------- 459
Cdd:TIGR01782 485 AAGGGTYTYASTAPNT------YTVTEdTTAAYAMANFDTGLRLRGNVGVRYERtdQTSDGwqsqpaangtgsvlvpvsa 558
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  460 ----NNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGvgcymmGNDDLKAETSINKEIG 535
Cdd:TIGR01782 559 drdyTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDGTGGTVTVSG------GNPDLKPYESDNLDLS 632
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  536 LEWK-RDGWLAGVTWFRNDYRNKIeaGYAPIGQTSTGKVTTDIYQWE-----NVPKA-VVEGLEgslnvpvsdtINWTN- 607
Cdd:TIGR01782 633 LEWYfGPGGLLSAAVFYKDIKNFI--VTTTSTETNDGGGGLVVAGVLvsrpvNGGKAgKIRGVE----------LGYQQt 700
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  608 ---------------NITYMLQSKNKETG------DRLSIIPEYTLNSTLSWQVHQ---DVSlqstftwygkqqpkkYNY 663
Cdd:TIGR01782 701 fdflpgplsgfgvqaNYTYVDSEADPSVDgvqrrkLPLPGLSKNTANATLYYEKGGfsaRLS---------------YNY 765
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  664 KGQPVTGS-------EKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDkrqwragnaqttgnttTGAYMYGAG---AYT 733
Cdd:TIGR01782 766 RSDYLLDVggsninrLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTN----------------EPSRWYTGGkqrPRE 829
                         890
                  ....*....|....*.
gi 515951937  734 YNEPGRTWYMSVNTRF 749
Cdd:TIGR01782 830 YVETGRTYMLGLRYKF 845
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
3-706 5.43e-12

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 69.45  E-value: 5.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   3 KKIHSLALLVNL--GIYGVALpVMADDNTASAqhEDTMVITAAEQNLQAPGVS----------------TITADEIRKNP 64
Cdd:PRK09840  10 RQFHSLAFFAGLciGITPVAQ-ALAAEGQTNA--DDTLVVEASTPSLYAPDQSadpkfsqpladttqtiTVISEQVIKDQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  65 PARDVAEIIRTMPGVNL-----TGNSTSGQrgnnrQIDIRGMGPENTlILIDGkpvtsrnsIRlgwrgerdtrgDTGWVP 139
Cdd:PRK09840  87 GATNLTEALRNVPGVGTffageNGNTTTGD-----AIYMRGFDTSNS-IYVDG--------IR-----------DIGSIS 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 140 PEM--IERIEVIRGPAAARYGNGAAGGVVNIITKK--FDDQWHGSWNTylnapehkDEGSTKRTNFSLSGPLGGDFSFRM 215
Cdd:PRK09840 142 RDTfnTEQVEVIKGPSGTDYGRSAPTGSINMISKQprNDSGIDASASI--------GSAWFRRGTLDVNQVIGDTTAVRL 213
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 216 ygNLDKTQADAwdinqghqsdrtgayadtlpAGREGVENKdingvvRWDFAPmqSLEFEAG----------YSRQNNLYA 285
Cdd:PRK09840 214 --NVMGEKTHD--------------------AGRDKVKNE------RYGVAP--SVAFGLGtanrlylnylHVTQNNTPD 263
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 286 GDTQNTNNDNSSSGLVKKNYGKETNRIYRQNFAVTwNGGWDNGITTSNWAQYEH-----------TRNSRLGEGLAGGLE 354
Cdd:PRK09840 264 GGIPTIGLPGYSAPSAGRAALNHAGKVDTHNFYGT-DSDYDDSTTDTATMRFEHdindnttlrntTRWSRVKQDYLLTAI 342
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 355 GLfNSNKFTDTDLADV-----------------MLHSEINLPIDF---IVNQNLTLGTEWNQQRMKDSTSFTQTQQGGTI 414
Cdd:PRK09840 343 MG-GASNITTPTPSDVntwtwsrtantkdvsnkILTNQTNLTSTFytgSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNL 421
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 415 --PGMSEDRSPYT--------SAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNW---------SPSLNLSQGLG-- 473
Cdd:PRK09840 422 yhPDSSIHPGGLTrnganangQTDTFAIYAFDTLQLTRDWELNGGIRLDNYHTEYDSAtacggsgrgAITCPAGVAKGsp 501
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 474 --DDFTLKMGIARAYKAPSLYQTNPNYLLY-----SK---GQGCYASSDGVGCYMMGNDDLKAETSINKEIGLEW----K 539
Cdd:PRK09840 502 vtTVDTAKSGNLVNWKAGALYKLTENGNVYinyavSQqppGGSNFALAQSGSGNSANRTDFKPQKANTSEIGTKWqvldK 581
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 540 RDGWLAGVtwFRNDYRNKIeagyapigqtstgkVTTDIYQWENVPKAVVEGLEgsLNVPVSDTINWTNNITYMLQSKNKE 619
Cdd:PRK09840 582 RLLLTAAL--FRTDIENEV--------------EQNDDGTYSQYGKKRVEGYE--LSVAGNITPAWQVIAGYTQQKATVK 643
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 620 TG--------DRLSIIPEYTLNSTLSWQVHQDVSLQSTFTWYGKQQPKKYNYKGQPvtgsekDEVSPYSIVGLSATWDVT 691
Cdd:PRK09840 644 NGkdvaqdgsSSLPYTPEHAFTLWSQYQATDDLSVGGGARYIGSMHRGSDGAVGTP------AFTEGYWVADAKLGYRVN 717
                        810
                 ....*....|....*
gi 515951937 692 KNVSLTGGVDNVFDK 706
Cdd:PRK09840 718 RNLDLQLNVYNLFDT 732
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
52-172 9.46e-08

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 55.67  E-value: 9.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   52 VSTITADEIRKNPpardVAEIIRT----MPGVNLTgnSTSGQRGNNRQIDIRGM----GPENTLILIDGKPVTSR-NSIr 122
Cdd:TIGR04056  98 VSTVKAKELKKVP----VSNLSNAlqgkVAGVIIT--QSSGEPGGDAEIWIRGIssfgGNNSPLYVIDGVPRDNGlSDL- 170
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 515951937  123 lgwrgerdtrgdtgwvPPEMIERIEVIRGPAA-ARYGNGAAGGVVNIITKK 172
Cdd:TIGR04056 171 ----------------NPEDIESISVLKDASAtAIYGSRGANGVILITTKR 205
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
2-172 1.87e-07

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 54.77  E-value: 1.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937   2 NKKIHSLALLVNLGIYGVALPVMAddntASAQHEDTMVITAA---EQNLQAPgVSTITADE----------IRKNPPA-- 66
Cdd:PRK10044  10 NHSLRKIAVVVATAVSGMSVYAQA----AVEPKEETITVTAApapQESAWGP-AATIAAKRsatgtktdtpIEKTPQSis 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  67 ------------RDVAEIIRTMPGVnltgnsTSGQRGNNRQID---IRGMGPENTlilidgkpvtSRNSIRLGWRGERDT 131
Cdd:PRK10044  85 vvtaeemalhqpKSVKEALSYTPGV------SVGTRGASNTYDhliIRGFAASGQ----------SQNNYLDGLKLQGNF 148
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 515951937 132 RGDTGwVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKK 172
Cdd:PRK10044 149 YNDAV-IDPYMLERAELMRGPVSVLYGKSNPGGLLNMVSKR 188
PRK14050 PRK14050
TonB-dependent siderophore receptor;
52-176 2.79e-06

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 50.96  E-value: 2.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  52 VSTITADEIRKNPPARDVAEIIRTMPGVnltgnsTSGQRGNNRQID---IRGMGPENTLILIDGKPVTSrnsirLGWRGE 128
Cdd:PRK14050  83 VSVVGRQEMDDRGVTNKVDEALRYTPGV------LSQPFGTDGDTDwfyIRGFDATQTGVFLDGLNLFS-----YGFGGF 151
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 515951937 129 RdtrgdtgwVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQ 176
Cdd:PRK14050 152 Q--------IDPFMLERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDE 191
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
460-722 2.71e-04

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 44.19  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  460 NNWSPSLNLSQGLGDD--FTLKMGIARAYKAPSLYQTNPNYLLYSKGQgcyassdgvgcYMMGNDDLKAETSINKEIGLE 537
Cdd:pfam14905 157 FNLFPSASLSYKLNDNnsLQLSLYYRRIINRPSYWDLNPFRNYSDPYN-----------YSQGNPNLKPEYTNSFELGYT 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  538 WKrdgWLAGVTWFRNDYRNKIEAGYApigQTSTGKVTtdIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNIT-YMLQSK 616
Cdd:pfam14905 226 YK---WKLSLSLSYRYTNDVIQQTFI---TDDNDNVT--YTTYENLGKSNSYGLELSASFNPTKWWSLNGNLNgYYNKYK 297
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  617 NKETGDRLSIIPEYTLNSTLSWQVHQDVSLQSTFTWYGKQqpkkYNYKGqpvtgsekdEVSPYSIVGLSATWDVTKN-VS 695
Cdd:pfam14905 298 IDGSLNSDFSNFGFNWNLNNTFTLPKGWSLQLNGNYRSPR----VTGQG---------KIKPFYSLDLGLSKSFLKKkLT 364
                         250       260
                  ....*....|....*....|....*..
gi 515951937  696 LTGGVDNVFDKRQWRAGNAQTTGNTTT 722
Cdd:pfam14905 365 LSLNVNDIFNTRKFRSTTNYDNGFIQS 391
PRK10003 PRK10003
ferric-rhodotorulic acid outer membrane transporter; Provisional
18-706 8.42e-04

ferric-rhodotorulic acid outer membrane transporter; Provisional


Pssm-ID: 236640 [Multi-domain]  Cd Length: 729  Bit Score: 42.93  E-value: 8.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  18 GVALPVMADDNTASAQHEDTMVITAAEQNLQAPG-----VSTITADEIRKNPPaRDVAEII-------------RTMPGV 79
Cdd:PRK10003  23 CIALALLPSAAFAAPATEDTVIVEGSATAPVDDGeqdysVKTTSAGTKMQMTQ-RDIPQSVsivsqqrmedqqlQTLGEV 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  80 --NLTGNSTSGQRGNNRQIDIRGMGPENtlILIDGKPVTSRNSIRLGwrgerDTRGDTGwvppeMIERIEVIRGPAAARY 157
Cdd:PRK10003 102 meNTLGISKSQADSDRALYYSRGFQIDN--YMVDGIPTYFESRWNLG-----DALSDTA-----LFERVEVVRGATGLMT 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 158 GNGAAGGVVNIITKKFDDQ--------WHGSWNTylnapehkdegstKRTNFSLSGPLGGDFSFRMygnldktqadawDI 229
Cdd:PRK10003 170 GTGNPSAAINMVRKHATSRefkgdvsaEYGSWNK-------------QRYVADLQSPLTEDGKVRA------------RI 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 230 NQGHQSDRTgaYADtlpagREGVENKDINGVVRWDFAPMQSLEfeAGYSRQ----NNLYAGDTQNTNNDNSSSGLVKKN- 304
Cdd:PRK10003 225 VAGYQNNDS--WLD-----RYNSEKTFFSGIVDADLGDLTTLS--AGYEYQridvNSPTWGGLPRWNTDGSSNSYDRARs 295
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 305 ------YG-KETNRIY---RQNFAVTWNGGW----------------------DNGITTSNWAQYehtrnsrlGEGLAGG 352
Cdd:PRK10003 296 tapdwaYNdKEINKVFmtlKQRFADTWQATLnathsevefdskmmyvdayvdkATGMLVGPYSNY--------GPGFDYV 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 353 LEGLFNSNKfTDTDLADVMLHSEINLpidFIVNQNLTLGTEWNQQRMKDSTSFTQT---------QQGGTIPgmSEDRSP 423
Cdd:PRK10003 368 GGTGWNSGK-RKVDALDLFADGSYEL---FGRQHNLMFGGSYSKQNNRYFSSWANIfpdeigsfyNFNGNFP--QTDWSP 441
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 424 YTSAE-----IFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSlnlsqglGDDFTLKMGIaraykapsLYQTNPNY 498
Cdd:PRK10003 442 QSLAQddtthMKSLYAATRVSLADPLHLILGARYTNWRVDTLTYSME-------KNHTTPYAGL--------VYDINDNW 506
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 499 LLYSKGQGCYASS---DGVGCYmmgnddLKAETSINKEIGL--EWKRDGWLAGVTWFRNDYRNKIEAGYAPIgQTSTGKV 573
Cdd:PRK10003 507 STYASYTSIFQPQndrDSSGKY------LAPITGNNYELGLksDWMNSRLTTTLAIFRIEQDNVAQSTGTPI-PGSNGET 579
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 574 TtdiyqWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKE---------------TGDRLSIIPEYTLNSTLSW 638
Cdd:PRK10003 580 A-----YKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGnavnpnlprttvklfTRYRLPVMPELTVGGGVNW 654
                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937 639 Q--VHQDVSLQSTfTWYGKQqpkkynykgqpvtGSekdevspYSIVGLSATWDVTKNVSLTGGVDNVFDK 706
Cdd:PRK10003 655 QnrVYTDTVTPYG-TFRAEQ-------------GS-------YALVDLFTRYQVTKNFSVQGNVNNLFDK 703
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
10-217 1.48e-03

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 42.20  E-value: 1.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  10 LLVNLGIYGValpVMADDNTASAQHEDTMVITAAEQNLQApgVSTITADEIRKNPPaRDVAEIIRTMPGVNltgnstsgq 89
Cdd:PRK14049  46 LVVNGGSGGV---ITADGYVATSSATGAKVDTPFLETPQS--ISSVTEQQLKDRNP-QTLLETLAYTPGAR--------- 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515951937  90 rgnnrqIDIRGMGPENTLILIDGKPVTSRNSIRlgwRGERDTRGDTGW--VPPEMIERIEVIRGPAAARYGNGAAGGVVN 167
Cdd:PRK14049 111 ------VGAFGFDPRFDAFFVRGFDVTYTGVFR---DNLRQPGASSSIfkTEPYGLEGVSILRGPSSALYGASGAGGLFN 181
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 515951937 168 IITKKFDDQ-------WHGSWNTYlnapehkdegstkRTNFSLSGPL--GGDFSFRMYG 217
Cdd:PRK14049 182 LITKRPTEEplrevqvQYGTNNRY-------------QGQFDFSGPVneTDPVYYRLTG 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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