|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-613 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 690.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 1 MKKKKIIIPLVIAGSTIVLSFIGYLTILFLGHYVI----------DEKKLVFHASSKIIDQNGKELTSMYSENRDPVSLK 70
Cdd:COG0744 1 MAKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVAlyvadlpdpeELEDLALPQTSTIYDRDGTLIATLGDENREWVPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 71 EVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKEVIIAINLER 150
Cdd:COG0744 81 QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 151 DYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDTILNLMNEQ 230
Cdd:COG0744 161 KYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 231 GYLSSTETVEAKGRTLGIH-LKKKSETPWVDSYVDLMIKEAESQYSIshEQLLQGGYTITVPIDMNLQKVAYDAMKNNrY 309
Cdd:COG0744 241 GYITQAEADAAKAEPLTLVpPPNGAAAGKYPYFVDYVRRELEELLGE--DDLYRGGLKIYTTLDPKLQKAAEKAVKNV-L 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 310 FPGKSGSPEGSAVFIDNASGGVKAAIGGREYQARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSLLEDKEKSYDG 388
Cdd:COG0744 318 PEGKPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATqAKRQPGSTFKPF-VYAAAL-EQGYTPATTVDDEPVTFPG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 389 --YSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDIS-DKGLAIALGGLEkgVSPLQIAGAFH 465
Cdd:COG0744 396 ggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGITSPlDPNPSLALGTSE--VSPLEMASAYA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 466 TFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSVQNAWNMTRMLQQVVKGGTAQSGSYAG-DLAGKTGTTTysgvk 544
Cdd:COG0744 474 TFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGrPVAGKTGTTN----- 548
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515929724 545 gATKDAWFAGYTPSTTGAIWMGYDKTDNSHYLTGGSqYPVQLMKDILTTA--QITNETFQKPEGIKELQSP 613
Cdd:COG0744 549 -DNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTGGS-LPAPIWRDFMEAAleGLPVEDFPKPSGVVRIDEP 617
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
63-594 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 600.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 63 NRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKEV 142
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 143 IIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDT 222
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 223 ILNLMNEQGYLSSTETVEAKGRTLGIHLK-KKSETPWVDSYVDLMIKEAESQYsisHEQLLQGGYTITVPIDMNLQKVAY 301
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQtKKSEQYKAPYFVDYVIQELEEEY---GEELYTGGLKIYTTLDLDAQKAAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 302 DAMKNNRYFPGKSGS--PEGSAVFIDNASGGVKAAIGGREYQARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSL 378
Cdd:TIGR02074 238 KVLNTGLRVAGRRDGddLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATqAKRQPGSTFKPF-VYAAAL-EKGLTPATI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 379 LEDKEKSYDG---YSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDIS-DKGLAIALGGLEkg 454
Cdd:TIGR02074 316 VNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPlDPVLSLALGTVE-- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 455 VSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSVQNAWNMTRMLQQVVKGGTAQSGSYAG-DLAG 533
Cdd:TIGR02074 394 VSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARLPGrPVAG 473
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515929724 534 KTGTTTYSgvkgatKDAWFAGYTPSTTGAIWMGYDKTDNSHYLTGGSQYPVQLMKDILTTA 594
Cdd:TIGR02074 474 KTGTTQNW------RDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGGLAAPIWRDFMAEA 528
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
52-228 |
8.14e-89 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 275.55 E-value: 8.14e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 52 NGKELTSMYSENRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTN 131
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 132 DKTFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVL 211
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 515929724 212 HPDKNKQRRDTILNLMN 228
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
55-568 |
4.68e-81 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 275.47 E-value: 4.68e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 55 ELTSMYSENRD-PVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDK 133
Cdd:PRK11636 56 ELIAQYGEKRRiPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPER 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 134 TFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHP 213
Cdd:PRK11636 136 TLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSM 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 214 DKNKQRRDTILNLMNEQGYLSSTETVEAKGRTlgihLKKKSETPWVD---SYVDLMIK-EAESQYSishEQLLQGGYTIT 289
Cdd:PRK11636 216 DRAVARRNVVLSRMLDEGYITQAQYDQARSEP----IVANYHAPEIAfsaPYLSEMVRqEMYNRYG---ENAYEDGYRVY 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 290 VPIDMNLQKVAYDAMKNN-------------------------------------------------------------- 307
Cdd:PRK11636 289 TTITRKVQQAAQQAVRNNvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpavvtsanpqeatamlad 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 308 -----------RYF-PGKSGSPEG-----------------------------------SAVFIDNASGGVKAAIGGREY 340
Cdd:PRK11636 369 gssvalpmegvRWArPYRSDTQQGptprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsALVSINPQNGAVMALVGGFDF 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 341 QARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSLLEDKEKS-YDG-----YSPKNYDGQYEGRVTMVEALMKSKN 413
Cdd:PRK11636 449 NQSKFNRATqALRQVGSNIKPF-LYTAAM-DKGLTLASMLNDVPISrWDAgagsdWRPKNSPPQYAGPIRLRQGLGQSKN 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 414 TSAVWTLSQLGIDTSKSYLEKMGMDISD--KGLAIALGGleKGVSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGET-- 489
Cdd:PRK11636 527 VVMVRAMRAMGVDYAAEYLQRFGFPAQNivHTESLALGS--ASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVif 604
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 490 ------------------------VEKNRNKEERVFSVQNAWNMTRM--LQQVVKGGTAQSG--SYA------------- 528
Cdd:PRK11636 605 eakpkvacpecdipviygdtqksnVLENDDVENVATSQEQQNSSVPMpqLEQANQALVAQNGaqEYAphvintplaflik 684
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515929724 529 --------------------------GDLAGKTGTTTYSgvkgatKDAWFAGYTPSTTGAIWMGYD 568
Cdd:PRK11636 685 salntnifgepgwmgtgwragrdlkrRDIGGKTGTTNSS------KDAWFSGYGPGVVTSVWIGFD 744
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-613 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 690.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 1 MKKKKIIIPLVIAGSTIVLSFIGYLTILFLGHYVI----------DEKKLVFHASSKIIDQNGKELTSMYSENRDPVSLK 70
Cdd:COG0744 1 MAKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVAlyvadlpdpeELEDLALPQTSTIYDRDGTLIATLGDENREWVPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 71 EVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKEVIIAINLER 150
Cdd:COG0744 81 QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 151 DYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDTILNLMNEQ 230
Cdd:COG0744 161 KYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 231 GYLSSTETVEAKGRTLGIH-LKKKSETPWVDSYVDLMIKEAESQYSIshEQLLQGGYTITVPIDMNLQKVAYDAMKNNrY 309
Cdd:COG0744 241 GYITQAEADAAKAEPLTLVpPPNGAAAGKYPYFVDYVRRELEELLGE--DDLYRGGLKIYTTLDPKLQKAAEKAVKNV-L 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 310 FPGKSGSPEGSAVFIDNASGGVKAAIGGREYQARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSLLEDKEKSYDG 388
Cdd:COG0744 318 PEGKPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATqAKRQPGSTFKPF-VYAAAL-EQGYTPATTVDDEPVTFPG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 389 --YSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDIS-DKGLAIALGGLEkgVSPLQIAGAFH 465
Cdd:COG0744 396 ggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGITSPlDPNPSLALGTSE--VSPLEMASAYA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 466 TFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSVQNAWNMTRMLQQVVKGGTAQSGSYAG-DLAGKTGTTTysgvk 544
Cdd:COG0744 474 TFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGrPVAGKTGTTN----- 548
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515929724 545 gATKDAWFAGYTPSTTGAIWMGYDKTDNSHYLTGGSqYPVQLMKDILTTA--QITNETFQKPEGIKELQSP 613
Cdd:COG0744 549 -DNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTGGS-LPAPIWRDFMEAAleGLPVEDFPKPSGVVRIDEP 617
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
63-594 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 600.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 63 NRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKEV 142
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 143 IIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDT 222
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 223 ILNLMNEQGYLSSTETVEAKGRTLGIHLK-KKSETPWVDSYVDLMIKEAESQYsisHEQLLQGGYTITVPIDMNLQKVAY 301
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQtKKSEQYKAPYFVDYVIQELEEEY---GEELYTGGLKIYTTLDLDAQKAAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 302 DAMKNNRYFPGKSGS--PEGSAVFIDNASGGVKAAIGGREYQARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSL 378
Cdd:TIGR02074 238 KVLNTGLRVAGRRDGddLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATqAKRQPGSTFKPF-VYAAAL-EKGLTPATI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 379 LEDKEKSYDG---YSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDIS-DKGLAIALGGLEkg 454
Cdd:TIGR02074 316 VNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPlDPVLSLALGTVE-- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 455 VSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSVQNAWNMTRMLQQVVKGGTAQSGSYAG-DLAG 533
Cdd:TIGR02074 394 VSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARLPGrPVAG 473
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515929724 534 KTGTTTYSgvkgatKDAWFAGYTPSTTGAIWMGYDKTDNSHYLTGGSQYPVQLMKDILTTA 594
Cdd:TIGR02074 474 KTGTTQNW------RDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGGLAAPIWRDFMAEA 528
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
46-607 |
6.15e-180 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 532.43 E-value: 6.15e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 46 SKIIDQNGKELTSMYSENRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAK 125
Cdd:COG5009 48 SRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAK 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 126 NIFLTNDKTFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPS 205
Cdd:COG5009 128 NFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 206 TYSPVLHPDKNKQRRDTILNLMNEQGYLSSTETVEAKGRTLGIHLKKKSETPWVDSYVDLMIKEAESQYSIshEQLLQGG 285
Cdd:COG5009 208 RYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGE--DALYTGG 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 286 YTITVPIDMNLQKVAYDAMKNN---------------------------------------------------------- 307
Cdd:COG5009 286 LKVYTTLDPRLQEAAEKALRDGllaydrrhgyrgpeahldlaeedwdealaevpdvgdlrpavvlevddksarvglrdge 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 308 -------------RYFPGKSGSP---------------------------------EGSAVFIDNASGGVKAAIGGREYQ 341
Cdd:COG5009 366 tgtlpleglkwarPYINDNRRGPapksasdvlkpgdvirvrpvadggwrlrqipevQGALVALDPHTGAVLALVGGFDFE 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 342 ARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSLLEDKEKSYDG------YSPKNYDGQYEGRVTMVEALMKSKNT 414
Cdd:COG5009 446 QSKFNRATqAKRQPGSSFKPF-VYAAAL-DNGYTPATIINDAPIVFDDgggggvWRPKNYSGKFYGPTTLREALEKSRNL 523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 415 SAVWTLSQLGIDTSKSYLEKMGmdISDK---GLAIALGGLEkgVSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVE 491
Cdd:COG5009 524 VTVRLLQDVGIDYVIDYAERFG--IYSKlppNLSLALGSGE--VTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIY 599
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 492 KN---------------------RNKEERVFSVQNAWNMTRMLQQVVKGGTAQSGSYAG-DLAGKTGTTTYSgvkgatKD 549
Cdd:COG5009 600 RAdparacedcdaaewdgaeprlPDPAEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGrDIAGKTGTTNDS------KD 673
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515929724 550 AWFAGYTPSTTGAIWMGYDktDNS---HYLTGGS-------QYpvqlMKDILttAQITNETFQKPEGI 607
Cdd:COG5009 674 AWFVGFTPDLVAGVWVGFD--DPRslgRGETGGRaalpiwiDF----MKAAL--KDKPEKPFPVPEGI 733
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
64-610 |
6.14e-107 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 342.58 E-value: 6.14e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 64 RDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKnIFLTNDKTFLRKTKEVI 143
Cdd:COG4953 65 RLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR-LLEPRPRTLSGKLRQIL 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 144 IAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDTI 223
Cdd:COG4953 144 RALQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRV 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 224 LNLMNEQGYLSSTETVEAkgrtlgihlkkKSETPWVDSYVdlMIKEAesqysiSH--EQLLQ---GGYTITVPIDMNLQ- 297
Cdd:COG4953 224 LARLAEAGVIDAEEAALA-----------LLEPVPARRRP--LPQLA------PHlaRRLLRqlpGGTRIRTTLDAGLQr 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 298 ---KVAYDAMKNNRYFPGKSgspeGSAVFIDNASGGVKAAIGGREY--QARG--YNRVTAVRQPGSVFKPIaVYGPAMQE 370
Cdd:COG4953 285 rleRLVRRYVRRLKQNGIHN----AAVLVVDNRTGEVLAYVGSADFfdASRQgqVDMVRALRSPGSTLKPF-LYGLALDQ 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 371 KKFRPYSLLEDKEKSYDGYSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDISDK-----GLA 445
Cdd:COG4953 360 GLIHPETLLADVPTSFGGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLPpaehyGLS 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 446 IALGGLEkgVSPLQIAGAFHTFANEGVYKKPFFIQkitnddgetvEKNRNKEERVFSVQNAWNMTRMLQQV---VKGGTA 522
Cdd:COG4953 440 LILGGAE--VTLEELVGLYAALARGGEARPLRLLA----------GEPASPGRRLLSPGAAWLVRDILSDVprpDGAFGW 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 523 QSGSYAGDLAGKTGTTT-YsgvkgatKDAWFAGYTPSTTGAIWMG-YDKTDNSHyLTgGSQYPVQLMKDILTT--AQITN 598
Cdd:COG4953 508 RALDSPPPIAWKTGTSYgF-------RDAWAVGFTGRYTVGVWVGnPDGTPVPG-LT-GAEAAAPLLFDIFDLlpASRWP 578
|
570
....*....|..
gi 515929724 599 ETFQKPEGIKEL 610
Cdd:COG4953 579 LPFPPPAGLLRV 590
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
56-608 |
4.72e-106 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 339.39 E-value: 4.72e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 56 LTSMYSENRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTF 135
Cdd:TIGR02071 139 LYSPNGEQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 136 LRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGH----GVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVL 211
Cdd:TIGR02071 219 WRKANEAYMALILDARYSKDRILELYLNEVYLGQsgddAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWR 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 212 HPDKNKQRRDTILNLMNEQGYLSSTETVEAKGRTLGIHLKKKSETPWVdSYVDLMikEAESQYSISHEQLLQGGYTITVP 291
Cdd:TIGR02071 299 NPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQKKGGIISRQP-AFLQLV--RRELRQKLGDKVKDLSGLRIFTT 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 292 IDMNLQKVAYDAMKNN-RYFPGKSGSP--EGSAVFIDNASGGVKAAIGGREYQARGYNRV-TAVRQPGSVFKPiAVYGPA 367
Cdd:TIGR02071 376 LDPVSQSAAEQAVQETiPALKKKKKLPdlEAAMVVTDRFTGEVRAMVGGSDPQFAGFNRAlQARRQIGSLVKP-AVYLTA 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 368 M-QEKKFRPYSLLEDKEKSYDG-----YSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGM--DI 439
Cdd:TIGR02071 455 LsQPDKYRLNTWIEDQPLSIKLsngqvWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGInkDE 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 440 SDKGLAIALGGLEkgVSPLQIAGAFHTFANEGvYKKPFF-IQKITNDDGETVEKNRNKEERVFSVQNAWNMTRMLQQVVK 518
Cdd:TIGR02071 535 IPPVPSMLLGAIN--LTPYEVAQLYQTIASGG-NRAPLSaVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQ 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 519 GGTAQS-----GSYAgdLAGKTGTTTYSgvkgatKDAWFAGYTPSTTGAIWMGYDktDNSHY-LTGGSQyPVQLMKDILT 592
Cdd:TIGR02071 612 RGTARSlgadfPSLS--LAGKTGTTNDN------RDSWFAGIDGKEVTIIWLGRD--DNGPTkLTGASG-ALQVYARYLS 680
|
570
....*....|....*.
gi 515929724 593 TAQITNETFQKPEGIK 608
Cdd:TIGR02071 681 YQTPEPLLLVPPEGID 696
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
52-228 |
8.14e-89 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 275.55 E-value: 8.14e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 52 NGKELTSMYSENRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTN 131
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 132 DKTFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVL 211
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 515929724 212 HPDKNKQRRDTILNLMN 228
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
55-568 |
4.68e-81 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 275.47 E-value: 4.68e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 55 ELTSMYSENRD-PVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDK 133
Cdd:PRK11636 56 ELIAQYGEKRRiPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPER 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 134 TFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHP 213
Cdd:PRK11636 136 TLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSM 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 214 DKNKQRRDTILNLMNEQGYLSSTETVEAKGRTlgihLKKKSETPWVD---SYVDLMIK-EAESQYSishEQLLQGGYTIT 289
Cdd:PRK11636 216 DRAVARRNVVLSRMLDEGYITQAQYDQARSEP----IVANYHAPEIAfsaPYLSEMVRqEMYNRYG---ENAYEDGYRVY 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 290 VPIDMNLQKVAYDAMKNN-------------------------------------------------------------- 307
Cdd:PRK11636 289 TTITRKVQQAAQQAVRNNvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpavvtsanpqeatamlad 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 308 -----------RYF-PGKSGSPEG-----------------------------------SAVFIDNASGGVKAAIGGREY 340
Cdd:PRK11636 369 gssvalpmegvRWArPYRSDTQQGptprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsALVSINPQNGAVMALVGGFDF 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 341 QARGYNRVT-AVRQPGSVFKPIaVYGPAMqEKKFRPYSLLEDKEKS-YDG-----YSPKNYDGQYEGRVTMVEALMKSKN 413
Cdd:PRK11636 449 NQSKFNRATqALRQVGSNIKPF-LYTAAM-DKGLTLASMLNDVPISrWDAgagsdWRPKNSPPQYAGPIRLRQGLGQSKN 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 414 TSAVWTLSQLGIDTSKSYLEKMGMDISD--KGLAIALGGleKGVSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGET-- 489
Cdd:PRK11636 527 VVMVRAMRAMGVDYAAEYLQRFGFPAQNivHTESLALGS--ASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVif 604
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 490 ------------------------VEKNRNKEERVFSVQNAWNMTRM--LQQVVKGGTAQSG--SYA------------- 528
Cdd:PRK11636 605 eakpkvacpecdipviygdtqksnVLENDDVENVATSQEQQNSSVPMpqLEQANQALVAQNGaqEYAphvintplaflik 684
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515929724 529 --------------------------GDLAGKTGTTTYSgvkgatKDAWFAGYTPSTTGAIWMGYD 568
Cdd:PRK11636 685 salntnifgepgwmgtgwragrdlkrRDIGGKTGTTNSS------KDAWFSGYGPGVVTSVWIGFD 744
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
62-568 |
1.71e-77 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 264.01 E-value: 1.71e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 62 ENRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKE 141
Cdd:PRK14850 155 KKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 142 VIIAINLERDYSKDKLLEMYLNQLYFGHG----VYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNK 217
Cdd:PRK14850 235 IYMALILDRFYSKDRILELYLNEVYLGQDgneqIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 218 QRRDTILNLMNEQGYLSSTETVEAKGRTLGIhlKKKSETPWV-DSYVDLMIKEAESQYSISHEQLlqGGYTITVPIDMNL 296
Cdd:PRK14850 315 KRRNLVLFLLYKQKVITRKLYKDLCSRPLNV--QSKGNIISShPAFIQLVCEEFHKKIHYPFKNF--SGTKIFTTLDYIS 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 297 QKVAYDAMK------NNRYfpgKSGSPEGSAVFIDNASGGVKAAIGGREYQARGYNRVTAVRQP-GSVFKPIAVYGPAMQ 369
Cdd:PRK14850 391 QNAAEQAVKigipilKRKK---RLKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSiGSLSKPITYLTALSQ 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 370 EKKFRPYSLLED-----KEKSYDGYSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGmdISDKGL 444
Cdd:PRK14850 468 PEKYHLNTWISDtpisiKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLG--ISSNYI 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 445 ----AIALGGLEkgVSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSVQNAWNMTRMLQQVVKGG 520
Cdd:PRK14850 546 tplpSISLGAIN--LTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSG 623
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 515929724 521 TAQSGSY---AGDLAGKTGTTTYSgvkgatKDAWFAGYTPSTTGAIWMGYD 568
Cdd:PRK14850 624 TAKSLGTifkEFSLAGKTGTTNNL------VDSWFVGIDGKQVVITWIGRD 668
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
54-610 |
3.68e-77 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 264.32 E-value: 3.68e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 54 KELTSMYS---ENRDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLT 130
Cdd:PRK09506 198 RLITMLQSpngEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLS 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 131 NDKTFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHG----VYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPST 206
Cdd:PRK09506 278 NERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGQSgddqIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASL 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 207 YSPVLHPDKNKQRRDTILNLMNEQGYLSSTETVEAKGRTLGIHLKKKSETPWvDSYVDLMIKEAESQYSISHEQLlqGGY 286
Cdd:PRK09506 358 YNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPKGGVISPQ-PAFMQMVRQELQAKLGDKVKDL--SGV 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 287 TITVPIDMNLQKVAYDAMknnryfpgKSGSP-----------EGSAVFIDNASGGVKAAIGGREYQARGYNRVTAVRQP- 354
Cdd:PRK09506 435 KIFTTLDPVSQDAAEKAV--------EEGIPalkkqrklsdlETAMVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSi 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 355 GSVFKPiAVYGPAM-QEKKFRPYSLLED-----KEKSYDGYSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTS 428
Cdd:PRK09506 507 GSLAKP-ATYLTALsQPDKYRLNTWIADapislRQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAV 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 429 KSYLEKMGM--DISDKGLAIALGGLekGVSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSVQNA 506
Cdd:PRK09506 586 TDTWIKLGVpkDQLNPVPAMLLGAL--NLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAA 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 507 WNMTRMLQQVVKGGTAQS--GSYAG-DLAGKTGTTTysgvkgATKDAWFAGYTPSTTGAIWMGYDKTDNSHyLTGGSQyP 583
Cdd:PRK09506 664 YLTLYTMQQVVQRGTGRQlgAKYPNlHLAGKTGTTN------DLVDSWFAGIDGKEVTITWVGRDNNQPTK-LYGASG-A 735
|
570 580
....*....|....*....|....*..
gi 515929724 584 VQLMKDILTTAQITNETFQKPEGIKEL 610
Cdd:PRK09506 736 MTIYQRYLENQTPTPLNLTPPEDIVDM 762
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
64-566 |
4.28e-54 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 199.16 E-value: 4.28e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 64 RDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKnIFLTNDKTFLRKTKEVI 143
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR-LLDPHPRTFGGKIRQLW 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 144 IAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDTI 223
Cdd:PRK11240 141 RALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKV 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 224 LNLMNEQGYLSSTETVEAkgrtlgihlkkKSETPW-----VDSYVDLMIKEAESQysiSHEQLlqggytITVPIDMNLQK 298
Cdd:PRK11240 221 LERMAEQGVWSAEQVKES-----------REEPVWlaprqMPQLAPLFARMMLGK---SKSDK------IVTTLDAGLQR 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 299 VAYDAMKNNRY-FPGKSGSpegSAVFIDNASGGVKAAIGGREYQ--AR-GY-NRVTAVRQPGSVFKPIaVYGPAMQEKKF 373
Cdd:PRK11240 281 RLEDLALNWKGrLPPRSSL---AMIVVDHTDMAVRGWVGSVDLNddSRfGHvDMVNAIRSPGSVLKPF-VYGLALDDGLI 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 374 RPYSLLEDKEKSYDGYSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDI-----SDKGLAIAL 448
Cdd:PRK11240 357 HPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLylpagAEPNLSLIL 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 449 GGleKGVSPLQIAGAFHTFANEGVYKKPffiqKITNDDgetveknRNKEERVFSVQNAWNMTRMLqqvvkGGTAQ----- 523
Cdd:PRK11240 437 GG--AGARLEDMVAAYSAFARHGKAAKL----RLQPDD-------PLLERPLMSPGAAWIIRRIM-----ADEAQplpda 498
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 515929724 524 SGSYAGDLAGKTGtTTYsgvkgATKDAWFAGYTPSTTGAIWMG 566
Cdd:PRK11240 499 ALPRVVPLAWKTG-TSY-----GYRDAWAIGVNARYVIGIWTG 535
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
2-241 |
1.00e-43 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 157.27 E-value: 1.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 2 KKKKIIIPLVIAGSTIVLSFIGyltilflghyvidekkLVFHASSKIidqNGKELTSMySENRDPVSLKEVPDKVAKAFV 81
Cdd:PRK13481 3 KSKRILLKILLTILIIIALFIG----------------IMYFLSTRD---NVDELRKI-ENKSSFVSADNMPEYVKGAFI 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 82 AVEDKRFYEHHGIDAQSISRAVYRDIlAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKEVIIAINLERDYSKDKLLEMY 161
Cdd:PRK13481 63 SMEDERFYKHHGFDLKGTTRALFSTI-SDRDVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQYSKNEILSFY 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 162 LNQLYFGHGVYGIQAAANYYF-------SKDVKDLTVSEGATLAAMPKAPSTYSPVLHPDKNKQRRDTILNLMNEQGYLS 234
Cdd:PRK13481 142 LNNIYFGDNQYTLEGAANHYFgttvnknSTTMSHITVLQSAILASKVNAPSVYNINDMSENFTQRVSTNLEKMKQQNYIN 221
|
....*..
gi 515929724 235 STETVEA 241
Cdd:PRK13481 222 ETQYQQA 228
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
64-227 |
4.18e-43 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 155.31 E-value: 4.18e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 64 RDPVSLKEVPDKVAKAFVAVEDKRFYEHHGIDAQSISRAVYRDILAGGKVEGGSTITQQLAKNIFLTNDKTFLRKTKEVI 143
Cdd:TIGR02070 55 HRWRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAW 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 144 IAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAAANYYFSKDVKDLTVSEGATLAAMPKAPSTYSpVLHPDKNKQRRDT- 222
Cdd:TIGR02070 135 ATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYD-ENRPGPYVRRKATw 213
|
....*
gi 515929724 223 ILNLM 227
Cdd:TIGR02070 214 ILKQM 218
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
319-591 |
7.98e-43 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 156.81 E-value: 7.98e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 319 GSAVFIDNASGGVKAAIGGREYQARGYNR------VTAVRQPGSVFKPIAVyGPAMQEKKFRPYSLLEDKEKSYDGYSP- 391
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIGplrnraVTSRYEPGSTFKPFTA-LAALDNGVLKPDETIFDWPGKQQGGKSi 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 392 KNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSYLEKMGMDISDK-GLAIALGGLEK---------------GV 455
Cdd:pfam00905 80 GDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGiGLPGENAGYLTpywlegatasfgiglTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 456 SPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVEKnrnkeERVFSVQNAWNMTRMLQQVVK--GGTAQSGSYAGDLAG 533
Cdd:pfam00905 160 TPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLN-----KLPISKSTAEKVKDMLRLVVNdgTGTGTAAVPGYKVAG 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515929724 534 KTGTTTYSGVKG-----ATKDAWFAGYTPStTGAIWMGYDKTDNSHYLTGGSqYPVQLMKDIL 591
Cdd:pfam00905 235 KTGTAQVAGPKGggyydGAQIGWFVGYAPA-DNPKYAFAVLIDDPKRYYGGK-VAAPIFKDIL 295
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
285-557 |
6.68e-37 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 146.12 E-value: 6.68e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 285 GYTITVPIDMNLQKVAYDAMKNN-RYFPGKSGSpegsAVFIDNASGGVKAA----------IGGREYQARgYNR-VTAVR 352
Cdd:COG0768 218 GKDLVLTIDSDLQKIAEEALKKAvEEYKAKSGA----VVVMDPKTGEILAMasypsfdpnlFVGGPDEPL-RNRaVQGTY 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 353 QPGSVFKPIAVYGpAMQEKKFRPYSLLEDK-EKSYDGYSPKNYDGQYEGRVTMVEALMKSKNTSAVWTLSQLGIDTSKSY 431
Cdd:COG0768 293 EPGSTFKPFTAAA-ALEEGVITPDTTFDCPgYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDY 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 432 LEKMGMDisdKGLAIALGGLEKG-----------------------VSPLQIAGAFHTFANEGVYKKPFFIQKITNDDGE 488
Cdd:COG0768 372 LKKFGLG---QKTGIDLPGEASGllpspkrwypgetatmsigqglsVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGE 448
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515929724 489 TVEKNRNKEERVFSVQNAWNMTRMLQQVV--KGGTAQSGSYAG-DLAGKTGTT-TYSGVKGATKD----AWFAGYTP 557
Cdd:COG0768 449 VVKEEPEVLRRVISPETAETVREGMEGVVnePGGTARRAAIPGyRVAGKTGTAqVVDIGNGGYYKgrhiASFVGFAP 525
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
283-557 |
1.70e-22 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 102.22 E-value: 1.70e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 283 QGGYTITVPIDMNLQKVAYDAMKNNRyfpgksgspeGSAVFIDNASGGVKAA--------------IGGREYQA------ 342
Cdd:TIGR03423 223 VPGKDLVLTIDARLQQAAEKALGGRR----------GAVVVMDPRTGEILAMvstpsfdpnlfvdgISSKDYKAllndpd 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 343 RG-YNRVT-AVRQPGSVFKPIaVYGPAMQEKKFRPYslledkEKSYDGyspknydGQYE--------------GRVTMVE 406
Cdd:TIGR03423 293 RPlLNRAIqGVYPPGSTFKPV-VALAALEEGVITPE------TRIYCP-------GYFQlggrrfrcwkrgghGRVDLRK 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 407 ALMKSKNTSAVWTLSQLGIDTSKSYL------EKMGMDISD--KGL-----------------------AIALGGLekGV 455
Cdd:TIGR03423 359 AIEESCDVYFYQLALRLGIDKIAEYAkrfgfgQKTGIDLPGekSGLvpsrewkrkrfgqpwypgdtlnvSIGQGYV--LV 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515929724 456 SPLQIAGAFHTFANEGVYKKPFFIQKITNDDGETVEKNRNKEERVFSV-QNAWN-MTRMLQQVVK--GGTAQ-SGSYAG- 529
Cdd:TIGR03423 437 TPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPLPIsPENLDvVREGMRDVVNgpGGTARrARLGLPy 516
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 515929724 530 DLAGKTGTT-TYSGVKGATKD-----------AWFAGYTP 557
Cdd:TIGR03423 517 KMAGKTGTAqVVSLKQGEKYDaeqiperlrdhALFVAFAP 556
|
|
| |
