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Conserved domains on  [gi|515568154|ref|WP_017000983|]
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MULTISPECIES: GNAT family N-acetyltransferase [Mammaliicoccus]

Protein Classification

N-acetyltransferase( domain architecture ID 1000386)

N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate; similar to Drosophila melanogaster arylalkylamine N-acetyltransferase 1 that catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin, and octopamine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RimI super family cl33885
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 64-144 4.70e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG0456:

Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 36.94  E-value: 4.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515568154  64 GFIWAKFDNKDNEVKVYNLFVSESYRN--------NkiaaklkkKLETWAIDKGASSIVSTVHAQNKSMLHINESMGYET 135
Cdd:COG0456    1 GFALLGLVDGGDEAEIEDLAVDPEYRGrgigrallE--------AALERARERGARRLRLEVREDNEAAIALYEKLGFEE 72

                         90
                 ....*....|....*....
gi 515568154 136 EK----------YIMRKHL 144
Cdd:COG0456   73 VGerpnyygddaLVMEKEL 91
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 64-144 4.70e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 36.94  E-value: 4.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515568154  64 GFIWAKFDNKDNEVKVYNLFVSESYRN--------NkiaaklkkKLETWAIDKGASSIVSTVHAQNKSMLHINESMGYET 135
Cdd:COG0456    1 GFALLGLVDGGDEAEIEDLAVDPEYRGrgigrallE--------AALERARERGARRLRLEVREDNEAAIALYEKLGFEE 72

                         90
                 ....*....|....*....
gi 515568154 136 EK----------YIMRKHL 144
Cdd:COG0456   73 VGerpnyygddaLVMEKEL 91
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 26-133 4.82e-04

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 37.50  E-value: 4.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515568154   26 REDQSTKVAESLEFEAIKRSLAYEESVVFGALDNQKCIGFIWA-KFDNKDNEVKVYNLFVSESYRNNKIAAKLKKKLETW 104
Cdd:pfam00583   8 LSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLsIIDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEW 87

                          90       100
                  ....*....|....*....|....*....
gi 515568154  105 AIDKGASSIVSTVHAQNKSMLHINESMGY 133
Cdd:pfam00583  88 ARERGCERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 64-144 4.70e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 36.94  E-value: 4.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515568154  64 GFIWAKFDNKDNEVKVYNLFVSESYRN--------NkiaaklkkKLETWAIDKGASSIVSTVHAQNKSMLHINESMGYET 135
Cdd:COG0456    1 GFALLGLVDGGDEAEIEDLAVDPEYRGrgigrallE--------AALERARERGARRLRLEVREDNEAAIALYEKLGFEE 72

                         90
                 ....*....|....*....
gi 515568154 136 EK----------YIMRKHL 144
Cdd:COG0456   73 VGerpnyygddaLVMEKEL 91
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 26-133 4.82e-04

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 37.50  E-value: 4.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515568154   26 REDQSTKVAESLEFEAIKRSLAYEESVVFGALDNQKCIGFIWA-KFDNKDNEVKVYNLFVSESYRNNKIAAKLKKKLETW 104
Cdd:pfam00583   8 LSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLsIIDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEW 87

                          90       100
                  ....*....|....*....|....*....
gi 515568154  105 AIDKGASSIVSTVHAQNKSMLHINESMGY 133
Cdd:pfam00583  88 ARERGCERIFLEVAADNLAAIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 40-134 7.22e-04

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 37.34  E-value: 7.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515568154  40 EAIKRSLAYEESVVFGAL-----DNQKCIGFIWAK-FDNKDNEVKvyNLFVSESYRNNKIAAKLKKKLETWAIDKGASSI 113
Cdd:COG0454   18 EALDAELKAMEGSLAGAEfiavdDKGEPIGFAGLRrLDDKVLELK--RLYVLPEYRGKGIGKALLEALLEWARERGCTAL 95

                         90       100
                 ....*....|....*....|.
gi 515568154 114 VSTVHAQNKSMLHINESMGYE 134
Cdd:COG0454   96 ELDTLDGNPAAIRFYERLGFK 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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