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Conserved domains on  [gi|515558517|ref|WP_016991400|]
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TonB-dependent receptor [Flavobacterium sp. ACAM 123]

Protein Classification

TonB-dependent receptor( domain architecture ID 20710189)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0015891|GO:0015267|GO:0055085
PubMed:  12409204
TCDB:  1.B.14

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
70-808 1.90e-71

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


:

Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 247.08  E-value: 1.90e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  70 IEVNSASAAIVFKLDPNNSLDEVVVTGNRSKvRSVLNSAVPIDKLYAEDLKSSGQVTFDKMLAYkIPSFNSSSqaiSDAT 149
Cdd:COG4771    8 LLLALAAQAADALAEDATELEEVVVTATRTE-QSLSDAPASVSVITAEEIEKLGATDLADALRL-LPGVSVTR---SGGR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 150 AHFDPADLRGLGPSRTLVLVNGKRKNQSALVYindtpgkgevGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNII 229
Cdd:COG4771   83 GGSSGISIRGLGGDRVLVLIDGVPVNNPALGG----------GGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINII 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 230 LKKQTNFTEVSLTSGVTSQGDGfNFGADLNSGFKIaDKGFVNFNISYLAQNKTnragkpgkddlfgvaaddaqwgdwlsR 309
Cdd:COG4771  153 TKKPTDELEGSVSLGYGSNGNG-TYSGSLSLGGPG-DKLSFLLSGSYRDRDGY--------------------------L 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 310 NPDLGMTIGLPDSKMGAFVVNAEYPLSEVTTVYAFGDVNIRKGTSYALYrapywvsdpnnllheAGTTYNGFQPTFETDI 389
Cdd:COG4771  205 DYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPT---------------LGDTEISSDNAGDRDT 269
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 390 FDNLGSIGLRSN-VFGFNADFSLTAGSNKVDYTVGnSLNVSLGANSPTQfeaggytFSQLVGNADFSRTF-DKVTFGFGT 467
Cdd:COG4771  270 TTDRGNYSLRYNgDLGDNLDLSLYYSRTDRDSTNG-SLGGSTGSFSDSD-------DTTYGLELDLTYPLgGNHTLTLGA 341
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 468 EIRREQFEaragqEESYVGGGaqsfpglqpanalKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFG----DNISWK 543
Cdd:COG4771  342 EYRYDDLD-----SSSFLGGA-------------DASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPR 403
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 544 VSSRYKLTNDVAIRASFSTGFRAPALHQIYLSNIQTlvsggrisnqgtfnnvdPAVIGLGVPKLDAEESQNIATGITFR- 622
Cdd:COG4771  404 LGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGT-----------------PGRYVLGNPDLKPETSDNYELGLEYRl 466
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 623 SGANFSASLDFYHIKVRNRVLFSGEVGFDGDDTTtnpveevlldnditsmkfFINAVNTITKGVDVVLNYKNLEIGTGRL 702
Cdd:COG4771  467 GNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQ------------------YENVGKARTYGLELELKYRLGKGLTLTA 528
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 703 GLNLasniantkIDGKIgtpailsangydifNRKEQGRILSARPNTKVLLGMNYDLNKTTFIFNNTYFGEVTWQHATDVA 782
Cdd:COG4771  529 SYTY--------LDSKI--------------DDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPPSGR 586
                        730       740
                 ....*....|....*....|....*.
gi 515558517 783 KDQTFAGKVITDLGVAYNFTSTLSAN 808
Cdd:COG4771  587 LEGYTPGYTLLDLRASYKLTKNLTLS 612
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
13-94 1.86e-17

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


:

Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 78.02  E-value: 1.86e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   13 IKGIVTDEN-GQPLPYSNVIEKETSNGVTTDGNGNFEIK-VKGFPVTLIAKYVGFQNKSIEVNSA---SAAIVFKLDP-N 86
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKnLPAGTYTLVVSFVGYKTQEKKVTVSndnTLDVNFLLKEdA 80

                  ....*...
gi 515558517   87 NSLDEVVV 94
Cdd:pfam13715  81 LLLDEVVV 88
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
70-808 1.90e-71

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 247.08  E-value: 1.90e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  70 IEVNSASAAIVFKLDPNNSLDEVVVTGNRSKvRSVLNSAVPIDKLYAEDLKSSGQVTFDKMLAYkIPSFNSSSqaiSDAT 149
Cdd:COG4771    8 LLLALAAQAADALAEDATELEEVVVTATRTE-QSLSDAPASVSVITAEEIEKLGATDLADALRL-LPGVSVTR---SGGR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 150 AHFDPADLRGLGPSRTLVLVNGKRKNQSALVYindtpgkgevGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNII 229
Cdd:COG4771   83 GGSSGISIRGLGGDRVLVLIDGVPVNNPALGG----------GGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINII 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 230 LKKQTNFTEVSLTSGVTSQGDGfNFGADLNSGFKIaDKGFVNFNISYLAQNKTnragkpgkddlfgvaaddaqwgdwlsR 309
Cdd:COG4771  153 TKKPTDELEGSVSLGYGSNGNG-TYSGSLSLGGPG-DKLSFLLSGSYRDRDGY--------------------------L 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 310 NPDLGMTIGLPDSKMGAFVVNAEYPLSEVTTVYAFGDVNIRKGTSYALYrapywvsdpnnllheAGTTYNGFQPTFETDI 389
Cdd:COG4771  205 DYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPT---------------LGDTEISSDNAGDRDT 269
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 390 FDNLGSIGLRSN-VFGFNADFSLTAGSNKVDYTVGnSLNVSLGANSPTQfeaggytFSQLVGNADFSRTF-DKVTFGFGT 467
Cdd:COG4771  270 TTDRGNYSLRYNgDLGDNLDLSLYYSRTDRDSTNG-SLGGSTGSFSDSD-------DTTYGLELDLTYPLgGNHTLTLGA 341
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 468 EIRREQFEaragqEESYVGGGaqsfpglqpanalKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFG----DNISWK 543
Cdd:COG4771  342 EYRYDDLD-----SSSFLGGA-------------DASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPR 403
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 544 VSSRYKLTNDVAIRASFSTGFRAPALHQIYLSNIQTlvsggrisnqgtfnnvdPAVIGLGVPKLDAEESQNIATGITFR- 622
Cdd:COG4771  404 LGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGT-----------------PGRYVLGNPDLKPETSDNYELGLEYRl 466
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 623 SGANFSASLDFYHIKVRNRVLFSGEVGFDGDDTTtnpveevlldnditsmkfFINAVNTITKGVDVVLNYKNLEIGTGRL 702
Cdd:COG4771  467 GNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQ------------------YENVGKARTYGLELELKYRLGKGLTLTA 528
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 703 GLNLasniantkIDGKIgtpailsangydifNRKEQGRILSARPNTKVLLGMNYDLNKTTFIFNNTYFGEVTWQHATDVA 782
Cdd:COG4771  529 SYTY--------LDSKI--------------DDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPPSGR 586
                        730       740
                 ....*....|....*....|....*.
gi 515558517 783 KDQTFAGKVITDLGVAYNFTSTLSAN 808
Cdd:COG4771  587 LEGYTPGYTLLDLRASYKLTKNLTLS 612
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
116-860 4.55e-52

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 193.05  E-value: 4.55e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 116 AEDLKSSGQVTFDKMLAYkIPSFNSSSQAISDAtahfDPADLRGLGPSRTLVLVNGKRKNQSALVYINDTPgkgevgtdm 195
Cdd:cd01347    7 AEDIEKQPATSLADLLRR-IPGVSVTRGGGGGG----STISIRGFGPDRTLVLVDGLPLASSNYGRGVDLN--------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 196 kSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNFTEVSLTSGVTSQGDGFNFGA--DLNSGFKIADKGFVNFN 273
Cdd:cd01347   73 -TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGGGgfDVSGALADDGAFGARLY 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 274 ISYLAQNktnragkpgkddlfGVAADDAQWGDWLSRNPDLgmtiglpdskMGAFvvnaEYPLSEVTTVYAFGDVNIRK-- 351
Cdd:cd01347  152 GAYRDGD--------------GTIDGDGQADDSDEERYNV----------AGKL----DWRPDDDTRLTLDAGYQDQDad 203
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 352 GTSYALYRAPYWVSDPNNLLHEAGTTYNGFQPTFETDIFDNLGSIGLRSNVFGFNADFSLTAGSNKVDYTVGNSLNVSLG 431
Cdd:cd01347  204 GPGGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAG 283
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 432 ANSPTQFEAGGYTFSQLVGNADFSRTFD----KVTFGFGTEIRREQFEARagqeesyvgggaqsfpglqpanalketrsN 507
Cdd:cd01347  284 GDLGRSGYSSERDTTQLGFDAGLNAPFGtgpvAHTLTLGVEYRREELDEK-----------------------------Q 334
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 508 VGVYTTLDYDMSEAFLIGGSIRYENY--------------SDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIY 573
Cdd:cd01347  335 TALYAQDTIELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY 414
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 574 lsniqtlvsggrisnqgtFNNVDPAVIGLGVPKLDAEESQNIATGITFRSGANFSASLDFYHIKVRNRVLFSGEVgfdgd 653
Cdd:cd01347  415 ------------------GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTN----- 471
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 654 dtttnpveevlldNDITSMKFFINAVNTITKGVDVVLNYkNLEIGTGrLGLNLASNIANTKIDgkigtpailsangydif 733
Cdd:cd01347  472 -------------TGLGLVTVYVNGGKARIRGVELEASY-DLTDGLG-LTGSYTYTDTEVKRT----------------- 519
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 734 NRKEQGRILSARPNTKVLLGMNYDLNKT--TFIFNNTYFGEvTWQHATDVAKDQTFAGKVITDLGVAYNFTSTLSANVMV 811
Cdd:cd01347  520 DGATTGNRLPGIPKHTANLGLDYELPDEglTAGGGVRYRGK-QYADTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGV 598
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|....*....
gi 515558517 812 NNLLNvypdlldtkGDVVTDLGGRFKYAWEVNQfgfSGTTFTAGLNFKF 860
Cdd:cd01347  599 NNLFD---------KDYYTSLSVRGSGLYGYYG---PGRTYYLSVSYKF 635
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
11-695 5.82e-25

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 111.91  E-value: 5.82e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   11 QTIKGIVTDENGQPLPYSNVIEKETSNGVTTDGNGNFEIKVkgfPV--TLIAKYVGFQNKSIEVNSASaAIVFKLDP-NN 87
Cdd:TIGR04056   1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKV---PPgaVLVFSYIGYKTQEVKVKGQK-NLNITLKEdTQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   88 SLDEVVVT--GNRSKvRSVLNSAVPIDklyAEDLKSSGQVTFDKMLAYKIPSFN---SSSQAISDATAHfdpadLRGlgp 162
Cdd:TIGR04056  77 ELDEVVVVgyGTQKK-KSLTGAVSTVK---AKELKKVPVSNLSNALQGKVAGVIitqSSGEPGGDAEIW-----IRG--- 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  163 SRTLvlvNGkrkNQSALVYINDTPGkgevGTDMKSIPFSAIERVEVLRDGAS-AQYGSDAIAGVVNIILKK-QTNFTEVS 240
Cdd:TIGR04056 145 ISSF---GG---NNSPLYVIDGVPR----DNGLSDLNPEDIESISVLKDASAtAIYGSRGANGVILITTKRgKEGKPKIS 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  241 LTSGVTSQG--------DGFNFGADLNSGFKIADKGFVN-FNISYLAQNKTNRAGKPG-----KDDLFGVAA-------- 298
Cdd:TIGR04056 215 YNAEFGFSTptrlpemlNAYEYAELYNEALLNRGSSPPDiYTDEEIEAYRNGLDPDLYpntdwQDEIFKRTAfnqrhnls 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  299 -----DDAQWGDWLSRNPDLGMTIGLpDSKMGAFVVNAEYPLSEVTTV-----YAFGDVNIRKGTSYALYRA-------- 360
Cdd:TIGR04056 295 vsggtEKARYYVSLGYYNEEGILKNS-DYKRYNFRANIDAKLTKTLKLslnvsGSLSKYNNPGGSTSNIWGAlmlfprgt 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  361 PYWV-------------SDPNNLLHEAGTTYNGFQPTFETDIFDNLGSI-----GLRsnvfgFNADFSLTAGSNK-VDYT 421
Cdd:TIGR04056 374 PYSTppvysdgyypaynSGNTSLQNPYALLNRGYNENERNRLNGNASLEqkitkGLK-----LKGTFSYDYSNYKnKKYY 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  422 VGNSLNVSLGANSPTQFEAGGYTFSQLVGNA--DFSRTFDKVTFG--FGTEIRREQFEARAGQEESYVGGGAQSfpGLQP 497
Cdd:TIGR04056 449 KNPYYYNATGGANNGYYSESNSRSRNYYLEAtlNYNRTFGKHNVSalLGYSQQENKSSSYGGLLDDLPSLDAGT--SDAS 526
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  498 ANALKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFGDN----------ISWKVsSRYKLTNDVA-------IRASF 560
Cdd:TIGR04056 527 VSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGnrwgffpsvsLGWRI-SEEKFMKKLKkwlsflkLRASY 605
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  561 -STGFRAPALHQIYLSNIqTLVSGGRISNQGTFNNVDPAVIG-LGVPKLDAE--ESQNIATGITFRSGaNFSASLDFYHI 636
Cdd:TIGR04056 606 gIVGNDNIGDRYPYLSLY-NLGDGGYNFGTNNGTSVTGITESrYGNPNLKWEktKKWNLGLDLGFFNN-RLSLTVDYYYK 683
                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515558517  637 KVRNrVLFS----GEVGFdgddttTNPveevlldnditsmkfFINAVNTITKGVDVVLNYKNL 695
Cdd:TIGR04056 684 KTKD-ILQSrslpSVTGY------SSP---------------YANIGKVKNKGVELSLNYRNK 724
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
339-819 3.55e-22

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 101.00  E-value: 3.55e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  339 TTVYAFGDVNIRKGTSYALYRAPYWVSDPNNLLHEAGTTYNGFQPTFETDIFD---NLGSIGLR---SNVFGFNADFSLT 412
Cdd:pfam00593   5 SLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDtdrKRLSLGYDydlGDGLSWLSTLRLG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  413 AGSNKVDYTVGNSLNvSLGANSPTQFEAGGYTFSQLVGNADFSRTFD-KVTFGFGTEIRREQFEARAGQEESYVGGgaqs 491
Cdd:pfam00593  85 LRYSSLDGDYTSNSS-GLSGAGDYLSDDRLYGLYGLDGDLELSLDLShDLLLGVELRTAGLDYRRLDDDAYDPYDP---- 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  492 fPGLQPANALKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFGDN--------------ISWKVSSRYKLTNDVAIR 557
Cdd:pfam00593 160 -ANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLY 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  558 ASFSTGFRAPALHQIYlsniqtlvsggrisnqGTFNNVDPAVIGLGVPKLDAEESQNIATGITFRSGaNFSASLDFYHIK 637
Cdd:pfam00593 239 ASYSRGFRAPSLGELY----------------GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDG-RLSLSLALFYID 301
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  638 VRNRVLFSGEVGFDGDDTTTnpveevlldnditsmkfFINAVNTITKGVDVVLNYKNLEIGTGRLGLNLASNIANTKIDG 717
Cdd:pfam00593 302 IKNLITSDPDGPGLGGTVYT-----------------YTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADADD 364
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  718 KigtpailsangydifnrkeqGRILSARPNTKVLLGMNYDLNKTTFIFNN----TYFGEVTWqhaTDVAKDQTFAGKVIT 793
Cdd:pfam00593 365 T--------------------GNPLPNVPRHTANLGLTYDFPLGGWGARLgaryVGSGERRY---GDAANTFKTPGYTLV 421
                         490       500
                  ....*....|....*....|....*.
gi 515558517  794 DLGVAYNFTSTLSANVMVNNLLNVYP 819
Cdd:pfam00593 422 DLSAGYRLNKNLTLRLGVNNLFDKYY 447
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
157-860 3.74e-22

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 102.01  E-value: 3.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKNQsalvyiNDTPGKGEVGTDMKSIP-FSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTN 235
Cdd:PRK13484  90 IRGLSGDYTLILVDGRRQSG------RESRPNGSGGFEAGFIPpVEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNN 163
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 236 FT-EVSLTSGVTSQGDGfNFGADLN-----SGFKIADK-GFVNFNISYLAQNKTNRAGKPGKDdlfgvaaddaqwgdwls 308
Cdd:PRK13484 164 QTwDGVLGLGGIIQEHG-KFGNSTTndfylSGPLIKDKlGLQLYGGMNYRKEDSISQGTPAKD----------------- 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 309 rNPDLGMTIglpdskmgAFVvnaeyPLSEVTTVYAFGDVNIRK----GTSYALYRAPYWVSDPNNLLhEAGTTYNGFQPT 384
Cdd:PRK13484 226 -NKNITATL--------QFT-----PTESQKFVFEYGKNNQVHtltpGESLDAWTMRGNLKQPNSKR-ETHNSRSHWVAA 290
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 385 fetdiFDNLGSIgLRSNVFGFNADFSLTAGSNKVDYTVGNSLNvslgansptqFEAGGYTFSQLVGNADFSRTFDKVTFG 464
Cdd:PRK13484 291 -----WNAQGEI-LHPEIAVYQEKVIREVKSGKKDKYNHWDLN----------YESRKPEITNTIIDAKVTAFLPENVLT 354
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 465 FGTeirreQFEARAGQEESYVGGG---AQSFPGLQPAnalketrsnvgVYTTLDYDMSEAFLIGGSIRYENYSDFGDNIS 541
Cdd:PRK13484 355 IGG-----QFQHAELRDDSATGKKtteTQSVSIKQKA-----------VFIENEYAATDSLALTGGLRLDNHEIYGSYWN 418
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 542 WKVSSRYKLTNDVAIRASFSTGFRAPALHQIYlSNIQTLVSGGRisnqgtfnnvdpaVIGLGVPKLDAEESQNIATGITF 621
Cdd:PRK13484 419 PRLYAVYNLTDNLTLKGGIAKAFRAPSIREVS-PGFGTLTQGGA-------------SIMYGNRDLKPETSVTEEIGIIY 484
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 622 RSGANFSASLDFYHIKVRNRvLFSGEVGfdgddtTTNPveevlldndITSMKFFI--NAVNTITKGVDVVLN---YKNLE 696
Cdd:PRK13484 485 SNDSGFSASATLFNTDFKNK-LTSYDIG------TKDP---------VTGLNTFIydNVGEANIRGVELATQipvYDKWH 548
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 697 IGTGRLGLNLASNIANTKIDGKigtpailSANGYDIfnrkeqgrILSARPNTKVLLGMNYDlNKTTFIFNNTYFGEVTWQ 776
Cdd:PRK13484 549 VSANYTFTDSRRKSDDESLNGK-------SLKGEPL--------ERTPRHAANAKLEWDYT-QDITFYSSLNYTGKQIWA 612
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 777 HATDVAKDQTF-AGKVITDLGVAYNFTStlsaNVMVN-NLLNVypdlLDTKGDVVTDLGGRfkyaWEVNQfgfsGTTFTA 854
Cdd:PRK13484 613 AQRNGAKVPRVrNGFTSMDIGLNYQILP----DTLINfAVLNV----TDRKSEDIDTIDGN----WQVDE----GRRYWA 676

                 ....*.
gi 515558517 855 GLNFKF 860
Cdd:PRK13484 677 NVRVSF 682
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
13-94 1.86e-17

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 78.02  E-value: 1.86e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   13 IKGIVTDEN-GQPLPYSNVIEKETSNGVTTDGNGNFEIK-VKGFPVTLIAKYVGFQNKSIEVNSA---SAAIVFKLDP-N 86
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKnLPAGTYTLVVSFVGYKTQEKKVTVSndnTLDVNFLLKEdA 80

                  ....*...
gi 515558517   87 NSLDEVVV 94
Cdd:pfam13715  81 LLLDEVVV 88
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
70-808 1.90e-71

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 247.08  E-value: 1.90e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  70 IEVNSASAAIVFKLDPNNSLDEVVVTGNRSKvRSVLNSAVPIDKLYAEDLKSSGQVTFDKMLAYkIPSFNSSSqaiSDAT 149
Cdd:COG4771    8 LLLALAAQAADALAEDATELEEVVVTATRTE-QSLSDAPASVSVITAEEIEKLGATDLADALRL-LPGVSVTR---SGGR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 150 AHFDPADLRGLGPSRTLVLVNGKRKNQSALVYindtpgkgevGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNII 229
Cdd:COG4771   83 GGSSGISIRGLGGDRVLVLIDGVPVNNPALGG----------GGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINII 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 230 LKKQTNFTEVSLTSGVTSQGDGfNFGADLNSGFKIaDKGFVNFNISYLAQNKTnragkpgkddlfgvaaddaqwgdwlsR 309
Cdd:COG4771  153 TKKPTDELEGSVSLGYGSNGNG-TYSGSLSLGGPG-DKLSFLLSGSYRDRDGY--------------------------L 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 310 NPDLGMTIGLPDSKMGAFVVNAEYPLSEVTTVYAFGDVNIRKGTSYALYrapywvsdpnnllheAGTTYNGFQPTFETDI 389
Cdd:COG4771  205 DYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPT---------------LGDTEISSDNAGDRDT 269
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 390 FDNLGSIGLRSN-VFGFNADFSLTAGSNKVDYTVGnSLNVSLGANSPTQfeaggytFSQLVGNADFSRTF-DKVTFGFGT 467
Cdd:COG4771  270 TTDRGNYSLRYNgDLGDNLDLSLYYSRTDRDSTNG-SLGGSTGSFSDSD-------DTTYGLELDLTYPLgGNHTLTLGA 341
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 468 EIRREQFEaragqEESYVGGGaqsfpglqpanalKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFG----DNISWK 543
Cdd:COG4771  342 EYRYDDLD-----SSSFLGGA-------------DASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPR 403
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 544 VSSRYKLTNDVAIRASFSTGFRAPALHQIYLSNIQTlvsggrisnqgtfnnvdPAVIGLGVPKLDAEESQNIATGITFR- 622
Cdd:COG4771  404 LGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGT-----------------PGRYVLGNPDLKPETSDNYELGLEYRl 466
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 623 SGANFSASLDFYHIKVRNRVLFSGEVGFDGDDTTtnpveevlldnditsmkfFINAVNTITKGVDVVLNYKNLEIGTGRL 702
Cdd:COG4771  467 GNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQ------------------YENVGKARTYGLELELKYRLGKGLTLTA 528
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 703 GLNLasniantkIDGKIgtpailsangydifNRKEQGRILSARPNTKVLLGMNYDLNKTTFIFNNTYFGEVTWQHATDVA 782
Cdd:COG4771  529 SYTY--------LDSKI--------------DDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPPSGR 586
                        730       740
                 ....*....|....*....|....*.
gi 515558517 783 KDQTFAGKVITDLGVAYNFTSTLSAN 808
Cdd:COG4771  587 LEGYTPGYTLLDLRASYKLTKNLTLS 612
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
116-860 4.55e-52

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 193.05  E-value: 4.55e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 116 AEDLKSSGQVTFDKMLAYkIPSFNSSSQAISDAtahfDPADLRGLGPSRTLVLVNGKRKNQSALVYINDTPgkgevgtdm 195
Cdd:cd01347    7 AEDIEKQPATSLADLLRR-IPGVSVTRGGGGGG----STISIRGFGPDRTLVLVDGLPLASSNYGRGVDLN--------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 196 kSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNFTEVSLTSGVTSQGDGFNFGA--DLNSGFKIADKGFVNFN 273
Cdd:cd01347   73 -TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGGGgfDVSGALADDGAFGARLY 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 274 ISYLAQNktnragkpgkddlfGVAADDAQWGDWLSRNPDLgmtiglpdskMGAFvvnaEYPLSEVTTVYAFGDVNIRK-- 351
Cdd:cd01347  152 GAYRDGD--------------GTIDGDGQADDSDEERYNV----------AGKL----DWRPDDDTRLTLDAGYQDQDad 203
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 352 GTSYALYRAPYWVSDPNNLLHEAGTTYNGFQPTFETDIFDNLGSIGLRSNVFGFNADFSLTAGSNKVDYTVGNSLNVSLG 431
Cdd:cd01347  204 GPGGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAG 283
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 432 ANSPTQFEAGGYTFSQLVGNADFSRTFD----KVTFGFGTEIRREQFEARagqeesyvgggaqsfpglqpanalketrsN 507
Cdd:cd01347  284 GDLGRSGYSSERDTTQLGFDAGLNAPFGtgpvAHTLTLGVEYRREELDEK-----------------------------Q 334
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 508 VGVYTTLDYDMSEAFLIGGSIRYENY--------------SDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIY 573
Cdd:cd01347  335 TALYAQDTIELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY 414
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 574 lsniqtlvsggrisnqgtFNNVDPAVIGLGVPKLDAEESQNIATGITFRSGANFSASLDFYHIKVRNRVLFSGEVgfdgd 653
Cdd:cd01347  415 ------------------GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTN----- 471
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 654 dtttnpveevlldNDITSMKFFINAVNTITKGVDVVLNYkNLEIGTGrLGLNLASNIANTKIDgkigtpailsangydif 733
Cdd:cd01347  472 -------------TGLGLVTVYVNGGKARIRGVELEASY-DLTDGLG-LTGSYTYTDTEVKRT----------------- 519
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 734 NRKEQGRILSARPNTKVLLGMNYDLNKT--TFIFNNTYFGEvTWQHATDVAKDQTFAGKVITDLGVAYNFTSTLSANVMV 811
Cdd:cd01347  520 DGATTGNRLPGIPKHTANLGLDYELPDEglTAGGGVRYRGK-QYADTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGV 598
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|....*....
gi 515558517 812 NNLLNvypdlldtkGDVVTDLGGRFKYAWEVNQfgfSGTTFTAGLNFKF 860
Cdd:cd01347  599 NNLFD---------KDYYTSLSVRGSGLYGYYG---PGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
89-816 5.26e-43

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 166.54  E-value: 5.26e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  89 LDEVVVTGNRSkVRSVLNSAVPIDKLYAEDLKSSGQVTFDKMLAYkIPSFNSSSQAISDATAHfdpadLRGLG--PSRTL 166
Cdd:COG1629    1 LEEVVVTATRT-DESLQDVPGSVSVISREQLEDQPATDLGDLLRR-VPGVSVTSAGGGAGQIS-----IRGFGggGNRVL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 167 VLVNGkrknqsalVYINDTPGkgeVGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNFTEVSLTSGVT 246
Cdd:COG1629   74 VLVDG--------VPLNDPSG---GDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYG 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 247 SQGDgFNFGADLNSGfkiADKGFVNFNISYLAQNktnragkpgkddlfgvaaddaqwgDWLSRNpdlgmtiglpDSKMGA 326
Cdd:COG1629  143 SYGT-YRASLSLSGG---NGKLAYRLSASYRDSD------------------------GYRDNS----------DSDRYN 184
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 327 FVVNAEYPLSEVTTVYAFGDVNIRKGTSYALYrapywvsdPNNLLHEAGTTYNGFQPTFE--TDIFDNLGSIGLRSNVFG 404
Cdd:COG1629  185 LRAKLGYQLGDDTRLTLSASYSDSDQDSPGYL--------TLAALRPRGAMDDGTNPYSNdtDDNTRDRYSLSLEYEHLG 256
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 405 FNADFSLTAGSNKVDYTVGNSLNVSLGANSPTQFEAGGYTFSQLVGNADFSRTF-DKVTFGFGTEIRREQFEARagqeES 483
Cdd:COG1629  257 DGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFgGKHTLLVGLDYQRQDLDGS----GY 332
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 484 YVGGGAQSFPGLQPANALKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFGD----------------NISWKVSSR 547
Cdd:COG1629  333 PLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVDdtvtgtdsasgsrsysAFSPSLGLT 412
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 548 YKLTNDVAIRASFSTGFRAPALHQIYLSNIQTLVsggrisnqgtfnnvdpavigLGVPKLDAEESQNIATGITFRS-GAN 626
Cdd:COG1629  413 YQLSPNLSLYASYSRGFRAPTFGELYANGTDPYS--------------------VGNPDLKPETSTNYELGLRYRLlDGR 472
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 627 FSASLDFYHIKVRNRVLFSGEVGFDGDDTttnpveevlldnditsmkFFINAVNTITKGVDVVLNYKNleigTGRLGLNL 706
Cdd:COG1629  473 LSLSLALFYSDVDNEILSVPLPNDSGFST------------------YYTNAGKARSYGVELELSYQL----TPGLSLNA 530
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 707 ASNIANTKIDGKIGTPAILSangydifnrkeqGRILSARPNTKVLLGMNYDLNKT-TFIFNNTYFGEvtwQHATDVAKDQ 785
Cdd:COG1629  531 SYSYTDAKFDDDTDGSADLD------------GNRLPGVPPLTANLGLTYEFPGGwSLGLGVRYVGD---RYLDDANTQG 595
                        730       740       750
                 ....*....|....*....|....*....|.
gi 515558517 786 TFAGKVITDLGVAYNFTSTLSANVMVNNLLN 816
Cdd:COG1629  596 APGGYTLVDLGAGYRFGDNLTLSLGVDNLFD 626
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
11-695 5.82e-25

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 111.91  E-value: 5.82e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   11 QTIKGIVTDENGQPLPYSNVIEKETSNGVTTDGNGNFEIKVkgfPV--TLIAKYVGFQNKSIEVNSASaAIVFKLDP-NN 87
Cdd:TIGR04056   1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKV---PPgaVLVFSYIGYKTQEVKVKGQK-NLNITLKEdTQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   88 SLDEVVVT--GNRSKvRSVLNSAVPIDklyAEDLKSSGQVTFDKMLAYKIPSFN---SSSQAISDATAHfdpadLRGlgp 162
Cdd:TIGR04056  77 ELDEVVVVgyGTQKK-KSLTGAVSTVK---AKELKKVPVSNLSNALQGKVAGVIitqSSGEPGGDAEIW-----IRG--- 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  163 SRTLvlvNGkrkNQSALVYINDTPGkgevGTDMKSIPFSAIERVEVLRDGAS-AQYGSDAIAGVVNIILKK-QTNFTEVS 240
Cdd:TIGR04056 145 ISSF---GG---NNSPLYVIDGVPR----DNGLSDLNPEDIESISVLKDASAtAIYGSRGANGVILITTKRgKEGKPKIS 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  241 LTSGVTSQG--------DGFNFGADLNSGFKIADKGFVN-FNISYLAQNKTNRAGKPG-----KDDLFGVAA-------- 298
Cdd:TIGR04056 215 YNAEFGFSTptrlpemlNAYEYAELYNEALLNRGSSPPDiYTDEEIEAYRNGLDPDLYpntdwQDEIFKRTAfnqrhnls 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  299 -----DDAQWGDWLSRNPDLGMTIGLpDSKMGAFVVNAEYPLSEVTTV-----YAFGDVNIRKGTSYALYRA-------- 360
Cdd:TIGR04056 295 vsggtEKARYYVSLGYYNEEGILKNS-DYKRYNFRANIDAKLTKTLKLslnvsGSLSKYNNPGGSTSNIWGAlmlfprgt 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  361 PYWV-------------SDPNNLLHEAGTTYNGFQPTFETDIFDNLGSI-----GLRsnvfgFNADFSLTAGSNK-VDYT 421
Cdd:TIGR04056 374 PYSTppvysdgyypaynSGNTSLQNPYALLNRGYNENERNRLNGNASLEqkitkGLK-----LKGTFSYDYSNYKnKKYY 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  422 VGNSLNVSLGANSPTQFEAGGYTFSQLVGNA--DFSRTFDKVTFG--FGTEIRREQFEARAGQEESYVGGGAQSfpGLQP 497
Cdd:TIGR04056 449 KNPYYYNATGGANNGYYSESNSRSRNYYLEAtlNYNRTFGKHNVSalLGYSQQENKSSSYGGLLDDLPSLDAGT--SDAS 526
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  498 ANALKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFGDN----------ISWKVsSRYKLTNDVA-------IRASF 560
Cdd:TIGR04056 527 VSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGnrwgffpsvsLGWRI-SEEKFMKKLKkwlsflkLRASY 605
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  561 -STGFRAPALHQIYLSNIqTLVSGGRISNQGTFNNVDPAVIG-LGVPKLDAE--ESQNIATGITFRSGaNFSASLDFYHI 636
Cdd:TIGR04056 606 gIVGNDNIGDRYPYLSLY-NLGDGGYNFGTNNGTSVTGITESrYGNPNLKWEktKKWNLGLDLGFFNN-RLSLTVDYYYK 683
                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515558517  637 KVRNrVLFS----GEVGFdgddttTNPveevlldnditsmkfFINAVNTITKGVDVVLNYKNL 695
Cdd:TIGR04056 684 KTKD-ILQSrslpSVTGY------SSP---------------YANIGKVKNKGVELSLNYRNK 724
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
92-386 1.51e-22

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 98.41  E-value: 1.51e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  92 VVVTGNRSKvRSVLNSAVPIDKLYAEDLKSSGQVTFDKMLAyKIPSFNSSSQAISDATAHFDpadLRGLGPSRTLVLVNG 171
Cdd:COG4206    1 VVVTATRLE-QSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQVSSSGGPGSAASIS---IRGLGSNQTLVLIDG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 172 krknqsalVYINDtPGKGevGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNFTEVSLTSGVTSQGdG 251
Cdd:COG4206   76 --------VPLND-PSLG--GVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSFG-T 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 252 FNFGADLNSGfkiADKGFVNFNISYL-AQNKTNRAGKPGKDDLFGVAADDAQWGDWLSRNPDLGMTIGLPDSKMGaFVVN 330
Cdd:COG4206  144 RRLSASLSGG---AGKFSYSLSASYRrSDGYRYNDPDLRNNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSERG-YPGA 219
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 515558517 331 AEYPLSEVTTVYAFGDVNIRKGTSYALYRAPYWVSDPNNLLHEAGTTYNGFQPTFE 386
Cdd:COG4206  220 VGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLS 275
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
339-819 3.55e-22

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 101.00  E-value: 3.55e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  339 TTVYAFGDVNIRKGTSYALYRAPYWVSDPNNLLHEAGTTYNGFQPTFETDIFD---NLGSIGLR---SNVFGFNADFSLT 412
Cdd:pfam00593   5 SLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDtdrKRLSLGYDydlGDGLSWLSTLRLG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  413 AGSNKVDYTVGNSLNvSLGANSPTQFEAGGYTFSQLVGNADFSRTFD-KVTFGFGTEIRREQFEARAGQEESYVGGgaqs 491
Cdd:pfam00593  85 LRYSSLDGDYTSNSS-GLSGAGDYLSDDRLYGLYGLDGDLELSLDLShDLLLGVELRTAGLDYRRLDDDAYDPYDP---- 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  492 fPGLQPANALKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYSDFGDN--------------ISWKVSSRYKLTNDVAIR 557
Cdd:pfam00593 160 -ANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLY 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  558 ASFSTGFRAPALHQIYlsniqtlvsggrisnqGTFNNVDPAVIGLGVPKLDAEESQNIATGITFRSGaNFSASLDFYHIK 637
Cdd:pfam00593 239 ASYSRGFRAPSLGELY----------------GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDG-RLSLSLALFYID 301
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  638 VRNRVLFSGEVGFDGDDTTTnpveevlldnditsmkfFINAVNTITKGVDVVLNYKNLEIGTGRLGLNLASNIANTKIDG 717
Cdd:pfam00593 302 IKNLITSDPDGPGLGGTVYT-----------------YTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADADD 364
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  718 KigtpailsangydifnrkeqGRILSARPNTKVLLGMNYDLNKTTFIFNN----TYFGEVTWqhaTDVAKDQTFAGKVIT 793
Cdd:pfam00593 365 T--------------------GNPLPNVPRHTANLGLTYDFPLGGWGARLgaryVGSGERRY---GDAANTFKTPGYTLV 421
                         490       500
                  ....*....|....*....|....*.
gi 515558517  794 DLGVAYNFTSTLSANVMVNNLLNVYP 819
Cdd:pfam00593 422 DLSAGYRLNKNLTLRLGVNNLFDKYY 447
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
157-860 3.74e-22

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 102.01  E-value: 3.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKNQsalvyiNDTPGKGEVGTDMKSIP-FSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTN 235
Cdd:PRK13484  90 IRGLSGDYTLILVDGRRQSG------RESRPNGSGGFEAGFIPpVEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNN 163
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 236 FT-EVSLTSGVTSQGDGfNFGADLN-----SGFKIADK-GFVNFNISYLAQNKTNRAGKPGKDdlfgvaaddaqwgdwls 308
Cdd:PRK13484 164 QTwDGVLGLGGIIQEHG-KFGNSTTndfylSGPLIKDKlGLQLYGGMNYRKEDSISQGTPAKD----------------- 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 309 rNPDLGMTIglpdskmgAFVvnaeyPLSEVTTVYAFGDVNIRK----GTSYALYRAPYWVSDPNNLLhEAGTTYNGFQPT 384
Cdd:PRK13484 226 -NKNITATL--------QFT-----PTESQKFVFEYGKNNQVHtltpGESLDAWTMRGNLKQPNSKR-ETHNSRSHWVAA 290
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 385 fetdiFDNLGSIgLRSNVFGFNADFSLTAGSNKVDYTVGNSLNvslgansptqFEAGGYTFSQLVGNADFSRTFDKVTFG 464
Cdd:PRK13484 291 -----WNAQGEI-LHPEIAVYQEKVIREVKSGKKDKYNHWDLN----------YESRKPEITNTIIDAKVTAFLPENVLT 354
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 465 FGTeirreQFEARAGQEESYVGGG---AQSFPGLQPAnalketrsnvgVYTTLDYDMSEAFLIGGSIRYENYSDFGDNIS 541
Cdd:PRK13484 355 IGG-----QFQHAELRDDSATGKKtteTQSVSIKQKA-----------VFIENEYAATDSLALTGGLRLDNHEIYGSYWN 418
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 542 WKVSSRYKLTNDVAIRASFSTGFRAPALHQIYlSNIQTLVSGGRisnqgtfnnvdpaVIGLGVPKLDAEESQNIATGITF 621
Cdd:PRK13484 419 PRLYAVYNLTDNLTLKGGIAKAFRAPSIREVS-PGFGTLTQGGA-------------SIMYGNRDLKPETSVTEEIGIIY 484
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 622 RSGANFSASLDFYHIKVRNRvLFSGEVGfdgddtTTNPveevlldndITSMKFFI--NAVNTITKGVDVVLN---YKNLE 696
Cdd:PRK13484 485 SNDSGFSASATLFNTDFKNK-LTSYDIG------TKDP---------VTGLNTFIydNVGEANIRGVELATQipvYDKWH 548
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 697 IGTGRLGLNLASNIANTKIDGKigtpailSANGYDIfnrkeqgrILSARPNTKVLLGMNYDlNKTTFIFNNTYFGEVTWQ 776
Cdd:PRK13484 549 VSANYTFTDSRRKSDDESLNGK-------SLKGEPL--------ERTPRHAANAKLEWDYT-QDITFYSSLNYTGKQIWA 612
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 777 HATDVAKDQTF-AGKVITDLGVAYNFTStlsaNVMVN-NLLNVypdlLDTKGDVVTDLGGRfkyaWEVNQfgfsGTTFTA 854
Cdd:PRK13484 613 AQRNGAKVPRVrNGFTSMDIGLNYQILP----DTLINfAVLNV----TDRKSEDIDTIDGN----WQVDE----GRRYWA 676

                 ....*.
gi 515558517 855 GLNFKF 860
Cdd:PRK13484 677 NVRVSF 682
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
90-816 4.69e-21

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 98.64  E-value: 4.69e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   90 DEVVVTGNRSKVRSVL-NSAVPIDK--LYAEDLKSSGQVTFDKMLAYkIP--SFNSSSQAISDATAhfdpadLRGLGPSR 164
Cdd:TIGR01786   1 DTITVTATRTADPQRRdLSVTPASVsvISREQLKSQQVRNLRDLLRY-EPgvSVVEGGRGGSQGIN------IRGLDKNR 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  165 TLVLVNGKRKNQSalvyindTPGKGEVGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNFtevsLTSG 244
Cdd:TIGR01786  74 VAVLVDGIRQNTS-------YGGQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADL----LKPG 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  245 VtsqgdgfNFGADLNSGFKIADKGFVNfNISYLAQNktnragkpgkDDLFGVAADDAQWGDWLSRNPDLGMTIGLPDSKM 324
Cdd:TIGR01786 143 K-------DLGGLSKLGYSSANNRFTQ-SVAAAGRN----------DDVDALVQATYRRGHELKNGNKANIGNESKRSKP 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  325 G--AFVVNA-----EYPLS-----EVTTVYAFGDVNIRKGTSYALYRAPYWVSDPN---------NLLHEAGTTY--NGF 381
Cdd:TIGR01786 205 NpsDYKSQSflaklGWQLNdahrlGLSLEYTQTDYDEPEMTNTSYLTKPLGAPLLSstvvlgdskTRDRRTGLDYelNPD 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  382 QPTFETDIFD-NLGSIGLRSNVFGFNAdfsltAGSNKVDYTVGNslnvslgaNSPTQFEAGGYTFSqlvgnadFSRTFDK 460
Cdd:TIGR01786 285 NSWLDTVKLAlDKQYIQLYNYLNATSA-----SDYPGVDKNGRY--------KDKYDYYTLGFDTN-------NKIEFSV 344
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  461 V--TFGFGTEIRREQFEARAGQEESYVggGAQSFPGLQPANAlKETRSNVGVYTTLDYDMSEAFLIGGSIRYENY----- 533
Cdd:TIGR01786 345 HslSLTYGLDRFKDKVSTGDSRRNLPT--AAYNLYGYEGENR-PVKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYktdpk 421
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  534 ----------SDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIYlsniqtlVSGGRISnqgtfnnvDPAVIGLG 603
Cdd:TIGR01786 422 adeskdygaiSKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELY-------GTGAHPG--------GGPYTFLP 486
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  604 VPKLDAEESQNIATGITFRSG-ANFSASLdfYHIKVRNRVLfsgevgfdgddtTTNPVEEVLLDNDITSMKF--FINAVN 680
Cdd:TIGR01786 487 NPNLKPETSKNWEIGINLHFDqLDFKVSY--FRNDYKDFID------------LGIGVTAKGNMAQVGSNTItnYVNIDN 552
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  681 TITKGVDVVLNYKNLEIGTGRLGLNLASNIANTKidGKigtpailsangydifnRKEQGRILSARPNTKVLLGMNYDLNK 760
Cdd:TIGR01786 553 ARIRGIELSGRYDLGSFFSGPDGWTTTLKYGYTK--GK----------------DSDTNPWLNAITPLKVVLGLGYDHPD 614
                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515558517  761 TTFIF--NNTYFGE-------VTWQHATDVAKDQTF--AGKVITDLGVAYNFTSTLSANVMVNNLLN 816
Cdd:TIGR01786 615 EKWGVglTLTFSGAkdavdayATYYENGEAAKAGPLrtPSYTVVDLYGYYKPNKNLTLRFGVYNLLD 681
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
75-816 1.52e-19

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 93.84  E-value: 1.52e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  75 ASAAIVFKLDPNNSLDEVVVTGNRSKVRSVLNSAVPIDKLYAEDLKSSGQVTFDKMLAY----KIPSFNSSSQA--ISda 148
Cdd:COG4772    9 LLLAAAAAAEAATTLETVVVTGSRAAEARLKDVPGSVSVVDREELENQAATSLREVLRRvpgvNVQEEDGFGLRpnIG-- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 149 tahfdpadLRGLGPSRT---LVLVNGkrknqsalVYINDTP-GKGEVGTDMksiPFSAIERVEVLRDGASAQYGSDAIAG 224
Cdd:COG4772   87 --------IRGLGPRRSrgiTLLEDG--------IPIAPAPyGDPAAYYFP---DLERMERIEVLRGAAALRYGPQTVGG 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 225 VVNIILKkqTNFTEVSLTSGVTSQGDGFnFGADLNSGFKIADkgfVNFNISYlaqnkTNRAGKPGKDDlfgvaaddaqwg 304
Cdd:COG4772  148 AINFVTR--TIPTAFGGELRVTGGSFGY-RRTHASVGGTVGN---FGYLVEY-----SRKRGDGFRDN------------ 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 305 dwlsrnpdlgmtiglPDSKMGAFVVNAEYPLSEVTTVYA-FGDVNIRKGT----SYALYRA-PYWVSDPNNllhEAGTTY 378
Cdd:COG4772  205 ---------------SGFDINDFNAKLGYRLSDRQELTLkFQYYDEDANTpgglTDAQFDAdPRQSYRPAD---QFDTRR 266
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 379 NGFQPTFETDIFDNLgsiglRSNVFGFNADFSLTaGSNKVDYTVGNSLNVSLGANsPTQFEAGGytfsqlvGNADFSRTF 458
Cdd:COG4772  267 TQLSLRYEHQLSDNT-----TLTTTAYYNDFSRN-WYIRQNTADPNTPGLGLRGN-PRGYRSYG-------IEPRLTHRF 332
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 459 D----KVTFGFGTEIRREQFEARagqeeSYVGGGAQSFPGLQPANALKETRSNVGVYTTLDYDMSEAFLIGGSIRYENYS 534
Cdd:COG4772  333 ElggvPHTLEVGLRYHREEEDRK-----QYVNTYGQGRSGAGLRRDRRFSADALAAYAQNRFELTGRLTLTPGLRYEHIR 407
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 535 ---------DFGDNISWKVSS---------RYKLTNDVAIRASFSTGFRAPalhqiylsniqtlvsggrisnqgTFNnvD 596
Cdd:COG4772  408 rdrtdrystRTGGDDSGSNSYseflpglglLYQLTDNLQLYANVSRGFEPP-----------------------TFG--D 462
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 597 PAVIGLGVPKLDAEESQNIATGITFRSGANFSASLDFYHIKVRNRVLFSGEVGFDGDDTTtnpveevlldnditsmkffi 676
Cdd:COG4772  463 LAYGNGGNPDLKPEKSWNYELGTRGRIGNGLSAEVALFYIDYDNELGSCSAAGGDRSTFT-------------------- 522
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 677 NAVNTITKGVDVVLNYKNLEIGTGRLGLNLASNIANTKIDGKIGTPailsangydifnrkEQGRILSARPNTKVLLGMNY 756
Cdd:COG4772  523 NAGETRHQGLELALDYDLLKGGGLGLPLFAAYTYTDAEFTSDFGPV--------------FAGNRLPYVPRHQLTAGLGY 588
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515558517 757 DLNKTTFIFNNTYFGEVTWQHATDVAKDQTfaGKV----ITDLGVAYNFTSTLSANVMVNNLLN 816
Cdd:COG4772  589 EHGGWTANLNGRYVSEQFTDAANTVADGSF--GKIpsytVLDLSASYDFGKNLSLFAGVNNLFD 650
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
89-816 1.75e-19

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 93.61  E-value: 1.75e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   89 LDEVVVTGNRSKVRSVLnSAVPIDKLYAEDLKSSGQVTFDKMLAYkIP------SFNSSSQAISdatahfdpadLRGLGP 162
Cdd:TIGR01785   1 LDTVTVTATRTRQVLSE-APASVSVISGEQIESKQANNLADALNT-VPgvdvtgGGRPPGQSIN----------IRGLQD 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  163 SRTLVLVNGKRKNqsalvyinDTPGKGEVGTDmkSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNF------ 236
Cdd:TIGR01785  69 NRVLVVVDGARQN--------YQRGGAHNGSL--FVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLlrpgql 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  237 --TEVSLTSGVTSQGDGFNFGAD---------LNSGFKIADKGFVNFNISYLAQNKTNRAGKPGKddlFGVAADDAQWGD 305
Cdd:TIGR01785 139 fgGLAKLSYGSNNNSFGGSVAVAgrlddnldaLVAATYRDGGNYRNGNKEEATNSAYVQKNLLAK---LGWQLDDAQRLE 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  306 WLSRNPDLGMTIglPDSKMGafvvNAEYPLSEVTTVYAfgDVNIRKGTSYALYRAPywvsdPNNLLHEAgttynGFQPTF 385
Cdd:TIGR01785 216 FSYFTTEGSLDE--AQNSGP----GTEYVLGSSSTLLA--SSTRDRSATLTYNWTP-----EDNPWLDA-----TASLYY 277
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  386 ETDIFDNlgsigLRSNVFGFNadfsltagSNKVDYTvgnslnvSLGANSPTQFEAGGYTFSQLVGNADFSRtfDKVTfgf 465
Cdd:TIGR01785 278 NRTENDN-----DRSARGVGR--------EEGYQYT-------TYGATLQNTSRFDVASWSTLTYGVDWMK--DKRR--- 332
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  466 gTEIRREqfearagqeesyvgggaqSFPGLQPANALKETRSNVGVYTTLDYDM-SEAFLIGGSIRYENYS---------- 534
Cdd:TIGR01785 333 -TESFDP------------------NSVTTIVPNPPSAKEYFFGLFLQDNIPLlDDRLTLSAGLRYDHYKlspkttadte 393
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  535 --DFGDN-ISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIYlsniqtlVSGGRISNQGTFNNVdpaviglGVPKLDAEE 611
Cdd:TIGR01785 394 avDRSYSrWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELY-------GTGDHPGTPGGYTFA-------PNPNLKPET 459
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  612 SQNIATGITFRSGANFSA--SLDFYHIKVRNRVLFSGEVGFDGDDTTTNPVeevlldNDITSmkfFINAVNTITKGVDVV 689
Cdd:TIGR01785 460 SKTWELGANLSFDNLLLDndQLQFKVAYFYNDVKDFIDLTIGVTDNVTAGM------NNITQ---YVNIDGARIRGIEAS 530
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  690 LNYKnleigTGRLGLNLASniantkidgkigtpailsanGYDIFNRKEQGRILSARPNTKVLLGMNYDLNKTTFIFN--- 766
Cdd:TIGR01785 531 ASYD-----AGLWATGLSY--------------------GYTIGKDQNTNQWLSNIPPLKLVVTVGYRFPDRRLDLGaka 585
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....
gi 515558517  767 NTYFGEVTWQHATDVAKDQTF--AGKVITDLGVAYNFTST--LSANVMVNNLLN 816
Cdd:TIGR01785 586 AYYERQSESPTTEDVAANGLLttPGYTVVDLYATYQPNAVkgLTVRFGVNNLTD 639
PRK13486 PRK13486
TonB-dependent receptor;
157-860 3.04e-19

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 92.78  E-value: 3.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKNQSALVYINdtpGKGEVGTDMKSiPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNF 236
Cdd:PRK13486  88 IRGMPASYTLILIDGVRQGGSSDVTPN---GFSAMNTGFMP-PLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADK 163
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 237 TEVSLTSGVTSQgdgfnfgadlnsgfkiadkgfvnfnisylaqnKTNRAGkpgkddlfgvaaDDAQWGDWlSRNPDlgmt 316
Cdd:PRK13486 164 WLSSVNAGLNLQ--------------------------------ESNKWG------------NSSQFNFW-SSGPL---- 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 317 igLPDSkmgafvvnaeyplsevTTVYAFGDVNIRKGTSY------ALYRAPYWVSDPNnllHEAGTTYNgFQPTFETDIF 390
Cdd:PRK13486 195 --VDDS----------------VSLQVRGSTQQRQGSSVtslsdtAATRIPYPTESQN---YNLGARLD-WKASEQDVLW 252
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 391 DNLGSIGLRSNvfgfNADFSLTAGSNKVDYTVGNSLN-VSLGANSptqfeagGYTFSQLVGNADFSRTFDKVTFGFGTEI 469
Cdd:PRK13486 253 FDMDTTRQRYD----NRDGQLGSLTGGYDRTLRYERNkISAGYDH-------TFTFGTWKSYLNWNETENKGRELVRSVL 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 470 RREQFeARAGQE-------------------ESY---VGGGAQSfPGLQPANALKET-----RSNVGVYTTLDYDMSEAF 522
Cdd:PRK13486 322 KRDKW-GLAGQPrelkesnlilnsllltplgESHlvtVGGEFQS-SSMKDGVVLASTgetfrQKSWSVFAEDEWHLTDAL 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 523 LIGGSIRYENYSDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIYLSniqtlVSGgrISNQGTFNNvdpavigL 602
Cdd:PRK13486 400 ALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKG-----ISG--VSGQGKTNL-------L 465
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 603 GVPKLDAEESQNIATGITFRSGANFSASLDFYHIKVRNRVlfsgeVGFDGDDTTTNpveevlldnditsmkfFINAVNTI 682
Cdd:PRK13486 466 GNPDLKPEESVSYEAGVYYDNPAGLNANVTGFMTDFSNKI-----VSYSINDNTNS----------------YVNSGKAR 524
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 683 TKGVDVVLNYKnLEIGTGRLGLNLASNIANTKIDGKIGTPaiLSANGYDIFNRKEQGRILSarpNTKVLLGMNYdlNKTT 762
Cdd:PRK13486 525 LHGVEFAGTLP-LWSEDVTLSLNYTWTRSEQRDGDNKGAP--LSYTPEHMVNAKLNWQITE---EVASWLGARY--RGKT 596
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 763 FIFNNTYFGEVTWQHATDVAKDQTFAGKVITDLGVAYNFTSTLSANVMVNNLLNV-YPDL-LDTKGDVVTDLGGRFKYAW 840
Cdd:PRK13486 597 PRFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKdYSDVsLYSAGKSTLYAGDYFQTGS 676
                        730       740
                 ....*....|....*....|
gi 515558517 841 EVNQFGFSGTTFTAGLNFKF 860
Cdd:PRK13486 677 STTGYVIPERNYWMSLNYQF 696
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
156-642 1.42e-18

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 90.97  E-value: 1.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 156 DLRGLGPSRTLVLVNGKR-KNQSALVYindtPGKGEVGT--DMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKK 232
Cdd:PRK13528  98 DIRGMGPENTLILIDGVPvTSRNSVRY----SWRGERDTrgDTNWVPPEMVERIEVIRGPAAARYGSGAAGGVVNIITKR 173
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 233 QTNFTEVSLTSgVTSQGDGFNFGADLNsgfkiadkgfVNFNISylaqnktnragkpgkddlfGVAADDA----QWGDWLS 308
Cdd:PRK13528 174 PTNDWHGSLSL-YTNQPESSKEGATRR----------ANFSLS-------------------GPLAGDAltmrLYGNLNK 223
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 309 RNPDlgmtiglpdskmgAFVVNAEYPlsevtTVYAFGDVNIRKGTSYALYRapyWVSDPNNLLH-EAGTTYNG------F 381
Cdd:PRK13528 224 TDAD-------------SWDINSSAG-----TKNAAGREGVRNKDINGVLS---WKMTPQQILDfEAGYSRQGniyagdT 282
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 382 QPTFETDIFDNLGSIGLRSNVFgFNADFSLTA------GSNKV----DYTVGNSLNVSLGANSPTQFEAG-GYTFSQLVG 450
Cdd:PRK13528 283 QNSNSSAVTESLAKSGKETNRL-YRQNYGLTHngiwdwGQSRLgfyyEKTNNTRMNEGLAGGGEGRITADqTFTTSRLES 361
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 451 -------NADFSRTFDKvTFGFGTEIRREQFEARAGQEESYVGGGAQSFPGLQPANALKETRSNVGVYTTLDYDMSEAFL 523
Cdd:PRK13528 362 yrtsgelNVPLNWLFEQ-TLTVGAEWNRDELNDPSSTSLTVKDGDIGGISGSAADRSSKNKSEISALYVEDNIEPVPGTN 440
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 524 IGGSIRYENYSDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQI---YLsniqtLVSGGrisNQGTFNNVDPAVI 600
Cdd:PRK13528 441 LIPGLRFDYHSEFGSNWSPSLNLSQELGDYFKVKAGIARAFKAPNLYQSsegYL-----LYSRG---NGCPKDITSGGCY 512
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 515558517 601 GLGVPKLDAEESQNIATGITFRSGaNFSASLDFYHIKVRNRV 642
Cdd:PRK13528 513 LVGNKNLDPEISVNKEIGLEFTVD-DYHASVTYFRNDYQNKI 553
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
13-94 1.86e-17

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 78.02  E-value: 1.86e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   13 IKGIVTDEN-GQPLPYSNVIEKETSNGVTTDGNGNFEIK-VKGFPVTLIAKYVGFQNKSIEVNSA---SAAIVFKLDP-N 86
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKnLPAGTYTLVVSFVGYKTQEKKVTVSndnTLDVNFLLKEdA 80

                  ....*...
gi 515558517   87 NSLDEVVV 94
Cdd:pfam13715  81 LLLDEVVV 88
PRK13483 PRK13483
ligand-gated channel protein;
157-816 9.49e-17

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 84.83  E-value: 9.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKNQSALVYINDTPGKGEVGTDmksiPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNF 236
Cdd:PRK13483  93 LRGMGSQYTLILVDGKRQSSRETRPNSDGPGVEQAWTP----PLAAIERIEVIRGPMSSLYGSDAIGGVINIITRKVPNE 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 237 TEVSLTSGVTSQGDgfNFGADLNSGfkiadkgfvNFnisYLAqnktnragKPGKDDLFGVAAddaqWGDWLSRNPDlgmt 316
Cdd:PRK13483 169 WQGEVRLDTTLQEN--SDSGNVYQA---------NF---FVN--------GPLIKDLLGLQL----YGQYTQREED---- 218
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 317 iglpdskmgafvvnaeyplsevTTVYAFGDVNIRKGTSyalyRAPYWVSDPNNLLHEAGTTyngfqptfetdifdnlgsi 396
Cdd:PRK13483 219 ----------------------DIEGGYRDKDARSLTA----KLALTPNEDHDIMLEVGTS------------------- 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 397 glrsnvfgfNADFSLTAGSNKVDYTVGNSLNVSLG-ANSPTQFEAGGYTFSQlVGNADF--SRTFdkvtfgfgteIRREQ 473
Cdd:PRK13483 254 ---------NQERDSTVGKTVAPLAPGESCGRRGCpESSTTEYERSTVSLSH-TGRWDFgtSDTY----------IQHEE 313
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 474 FEARA------------------GQEESYVGGGA------QSFPGLQPANALKETRSNVGVYTTLDYDMSEAFLIGGSIR 529
Cdd:PRK13483 314 FDNKSremkikntdfqsslvaplGQEHTLTFGAAynhqdlTDETSNQISDLTDISRTQWAVFSEDEWRIADDFALTGGLR 393
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 530 YENYSDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIylsniqtlVSG-GRISNQGtfnNVdpavigLGVPKLD 608
Cdd:PRK13483 394 LDHDENFGGHVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQT--------TPDwGQVSRGG---NI------YGNPDLK 456
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 609 AEESQNIATGITFRSGANFSASLDFYHIKVRN---RVLFSGEVGFD-----GDDTTTNpveevlldnditsmkffINAVN 680
Cdd:PRK13483 457 PETSLNKELGLYYDLGSGLTASLTVFYNEFKDkitRVACPATQCTDgpnqfGADPTTY-----------------VNIDE 519
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 681 TITKGVDVVLNYKNLEigtgrlGLNLASNIANTKIDGKIGtpailsangydifnrKEQGRILSARPNTKVLLGMNYdlnK 760
Cdd:PRK13483 520 AVTQGVEASLSYPITS------TLSLSGNYTYTDSEQKSG---------------AYKGSPLNQLPKHLFQASLNW---E 575
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515558517 761 TTFIFNN----TYFGE----VTWQHATD-VAKDQTFAgkvitDLGVAYNFTSTLSANVMVNNLLN 816
Cdd:PRK13483 576 PTDRLNSwarvNYRGEesqpTTGPSSSSfIAPSYTFL-----DLGANYQLTDNLKLSAGIYNLFD 635
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
156-815 3.39e-16

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 83.16  E-value: 3.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 156 DLRGLGPSRTLVLVNGKRKNQSALVyindTPG-KGEVGT--DMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKK 232
Cdd:PRK13524 100 DIRGMGPENTLILIDGKPVSSRNSV----RYGwRGERDTrgDTNWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKK 175
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 233 QTNFTEVSLTSgvtsqgdGFNFGADLNSGfkiADKGfVNFNISylaqnktnragKPGKDDLfgvaaddaqwgdwlsrnpD 312
Cdd:PRK13524 176 PTGEWHGSWNT-------YFNAPEHKAEG---ATKR-TNFSLS-----------GPLGDEL------------------S 215
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 313 LGMTIGLPDSKMGAFVVNAEYPlSEVTTVYAFGDVNIRKGTS----YALYRapyWVSDPNN-LLHEAGTTYNG------F 381
Cdd:PRK13524 216 FRLYGNLNKTQADAWDINQGHQ-SARTGSYAGTLPAGREGVInkdiNGLLR---WDFAPLQsLELEAGYSRQGnlyagdT 291
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 382 QPTFETDIFDNLgsIGLRSNVFgFNADFSLTAGSN-----------KVDYTVGNSLNVSLGANSPTQFEAGGYTFS---- 446
Cdd:PRK13524 292 QNTNSDALVKSL--YGKETNRM-YRQNYALTHRGGwdngvstsnyaQYEHTRNSRLPEGLAGGTEGIFNEKATQFStidl 368
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 447 -QLVGNADFSRTFD---KVTFGFGTEIRREQFEARAGQEESYVGGGaqSFPGLQPANALKETRS-NVGVYTTLDYDMSEA 521
Cdd:PRK13524 369 dDVMLHSEVNLPFDllvNQTLTLGTEWNQQRMKDPSSNTQALTSGG--AIPGVSATGRSPYSKAeIFSLFAEDNMELTDS 446
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 522 FLIGGSIRYENYSDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQI---YLsniqtLVSGGrisnQGTFNNVDPA 598
Cdd:PRK13524 447 TMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQTnpnYI-----LYSKG----QGCYASAGNG 517
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 599 VIGLGVPKLDAEESQNIATGITF-RSGANfsASLDFYHIKVRNRVlfsgEVGfdgddtttnpveevlldnditsmkffIN 677
Cdd:PRK13524 518 CYLQGNDDLKAETSVNKEIGLEFkRDGWL--AGLTWFRNDYRNKI----EAG--------------------------YV 565
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 678 AVNTITKGVDVVLNYKN--------LEigtGRLGLNLASNIA-NTKIdgkigTPAILSANgydifnrKEQGRILSARPNT 748
Cdd:PRK13524 566 PVGTNSVGKTDIYQWENvpkavvegLE---GTLNVPVSETVNwTNNL-----TYMLQSKN-------KTTGDPLSIIPEY 630
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515558517 749 KVLLGMNYDL-NKTTFIFNNTYFGE-------VTWQHATDVAKdQTFAGKVITDLGVAYNFTSTLSANVMVNNLL 815
Cdd:PRK13524 631 TLNSTLSWQAtEDLSLQSTFTWYGKqkpkkynYKGQPVTGSAT-KEVSPYSIVGLSATYDVTKNVSLTGGVDNLF 704
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
103-225 7.17e-16

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 74.23  E-value: 7.17e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  103 SVLNSAVPIDKLYAEDLKSSGQVTFDKMLAYkIPSFNSSSQAISDATAhfdpADLRGLGPSRTLVLVNGKRKNqsalvyi 182
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSVSSGGGGGGSS----ISIRGFGSNRVLVLVDGVPLN------- 68
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 515558517  183 ndTPGKGEVGTDMksIPFSAIERVEVLRDGASAQYGSDAIAGV 225
Cdd:pfam07715  69 --SGGGGSVDLNS--IDPEDIERVEVLKGPASALYGSGAIGGV 107
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
197-816 5.99e-14

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 75.68  E-value: 5.99e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 197 SIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKK--QTNFTEVSLTSGvtsQGDGFNFGADLNsgFKIADKGFVNFNI 274
Cdd:COG4774   75 RRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRptDEPFTEVTLTYG---SDGQRRATLDVN--GPLGDDLAYRLNG 149
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 275 SYlAQNKTNRAGkpGKDDLFGVAAD-DAQWGDWLSrnpdlgmtiglpdskmgaFVVNAEYplSEVTTVYAFGDVNIRKGT 353
Cdd:COG4774  150 MY-RDSDSYRDG--VDNDRWGIAPSlTWRLGDRTR------------------LTLDYEY--QDDDRTPDYGVPAVANGR 206
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 354 SYALYRAPYWvSDPNNLLHeagTTYNGFQPTFETDifdnlgsiglrsnvfgFNADFSLTAGSNKVDYTVGNSLNVSLGAN 433
Cdd:COG4774  207 PVDVDRSTFY-GQPDDYSD---SETDSATLRLEHD----------------FNDNWTLRNALRYSDYDRDYRNTYPTGGN 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 434 SPTQFEAGGYTFSQ----LVGNADFSRTFD----KVTFGFGTEIRREQFEARAGQEESYVGGG-------AQSFPGLQPA 498
Cdd:COG4774  267 ATGTVTRSAYRRDQdndtLSNQTDLTGKFDtggvKHTLLAGVEYSREDSDNARYSGGGTAPTVnlynpvyGAPVTGPTLG 346
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 499 NALKETRSN-VGVYTTLDYDMSEAFLIGGSIRYENY-SDFGDNI-------------SWKVSSRYKLTNDVAIRASFSTG 563
Cdd:COG4774  347 GADNDSRTDtTGLYLQDTISLTDRWSLLAGLRYDRFdTDYTDRTtgattssyddsafSPRAGLVYKPTPNLSLYASYSTS 426
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 564 FRAPAlhqiylsniqtlvsggrISNQGTFNNVDpaviglgvpkLDAEESQNIATGI--TFRSGaNFSASLDFYHIKVRNR 641
Cdd:COG4774  427 FNPGG-----------------GAPSLSNAGQA----------LDPEKSRQYEVGVkwDLLDG-RLSLTAALFRIEKTNV 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 642 VLfsgevgfdGDDTTTNpveevlldnditsmkFFINAVNTITKGVDVVLnyknleigTGRL--GLNLASNIANTkiDGKi 719
Cdd:COG4774  479 RT--------TDPANPG---------------VYVQTGEQRSRGVELEA--------TGELtpGWSVLAGYTYL--DAE- 524
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 720 gtpaILSANGYDifnrkEQGRILSARPNTKVLLGMNYDLNKT--TFIFNNTYFGEVtwqhATDVAKDQTFAGKVITDLGV 797
Cdd:COG4774  525 ----ITKSANAA-----NVGNRLPNVPRHSASLWTTYDLPLPglTLGGGVRYVGSR----YADAANTVKLPSYTRFDAGA 591
                        650
                 ....*....|....*....
gi 515558517 798 AYNFTSTLSANVMVNNLLN 816
Cdd:COG4774  592 SYRLNKNLTLRLNVNNLTD 610
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
157-255 2.76e-13

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 73.77  E-value: 2.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKN-QSALVYINDTpgkgevgtDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTN 235
Cdd:PRK10064  91 IRGLDSSYTLILIDGKRVNsRNAVFRHNDF--------DLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQ 162
                         90       100
                 ....*....|....*....|....*
gi 515558517 236 FTEVSLTSGVTSQ-----GDGFNFG 255
Cdd:PRK10064 163 KWHGTVTVDTTIQehrdrGDTYNGQ 187
PRK13513 PRK13513
ligand-gated channel protein;
157-720 3.60e-13

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 73.26  E-value: 3.60e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKNQSALVYINDTPGKgEVGTdmkSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKK---- 232
Cdd:PRK13513  95 IRGMAAKYTLILVDGKRVDTRSTRPNSDGSGI-EQGW---LPPLAAIERIEVVRGPMSSLYGSDAMGGVINIITRKvqke 170
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 233 -------QTNFTEVSlTSGVTSQGDGFNFGADLNS--GFKIA--------DKgFVNfniSYLAQNKTNRAGK----PGKD 291
Cdd:PRK13513 171 whgslraDATLQEDS-KSGDIFQTNAYASGPLIDGllGLKVSgllshrseDK-IID---GYNEQRMRNGTATfsltPDDN 245
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 292 DLFGV-AADDAQwgdwlSRNPDLGMTIGLPDSKmgafvvnaeyplsevttvyafgDVNIRKGTSYALYRAPYWvsDPNNL 370
Cdd:PRK13513 246 NEFDFeIGRYVQ-----DRNSTPGRTLALNGTN----------------------SDTQYDRNNYAITHNGYY--DFGNS 296
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 371 lheagTTYngfqptFETDIFDNLG-SIGLRSNVFgfnadfsltagsnkvdytvgnslnvslgaNSPTQFEAGGYTFSqlv 449
Cdd:PRK13513 297 -----TSY------IQRDETRNPSrQMKSVDTIF-----------------------------NTQTSFLLDDHTLS--- 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 450 gnadfsrtfdkvtfgFGTEIRREQFEARAGQEESYvgggaqsfpglqpANALKETRSNVGVYTTLDYDMSEAFLIGGSIR 529
Cdd:PRK13513 334 ---------------LGGQYRYEELYDKGNQLPSA-------------SDLNKLTRWSWALFAEDEWQMTNDFALTGGIR 385
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 530 YENYSDFGDNISWKVSSRYKLTNDVAIRASFSTGFRAPALHQIYlsniqtlVSGGRISNQGTfnnvDPAVIgLGVPKLDA 609
Cdd:PRK13513 386 MDQDQNYGTHWTPRLYGVWHLADQWTLKGGVSTGYRSPDLRQAT-------DNWGQLTGGGG----LPALI-LGNSDLKP 453
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 610 EESQNIATGITFRSGANFSASLDFYHIKVRNRVLfsgEVGFDGDDTTTNPVEEVLLDNDITSMKFFINAVNtiTKGVDVV 689
Cdd:PRK13513 454 EKSISQEIGILWDNQENLNASVTLFNTDFKDKIT---EVRNCDTTNTDGQCVFNGINYDFISDRINVDKAN--MRGVEAT 528
                        570       580       590
                 ....*....|....*....|....*....|.
gi 515558517 690 LNYKNLEigtgrlGLNLASNIANTKIDGKIG 720
Cdd:PRK13513 529 FNWDINQ------AWSLATNYTFTQSEQKSG 553
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
157-249 5.22e-11

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 66.17  E-value: 5.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 157 LRGLGPSRTLVLVNGKRKNQSALVYindtpgkgevGTDMKSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNF 236
Cdd:PRK10641  88 IRGTNSSHVLVLIDGVRLNQAGISG----------SADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPG 157
                         90
                 ....*....|...
gi 515558517 237 TEvsLTSGVTSQG 249
Cdd:PRK10641 158 TT--LSAGWGSNG 168
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
197-816 1.13e-09

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 62.22  E-value: 1.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 197 SIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKK--QTNFTEVSLTSGvtsQGDGFNFGADLNSgfKIADKGFVNFNI 274
Cdd:COG4773  132 QPDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRptAEPQGEVSLSAG---SWDTYRATADVGG--PLNEDGTLRYRL 206
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 275 SYLAQNK-TNRAGkpGKDDLFGVAAD-DAQWGDWLSrnpdlgmtiglpdskmgaFVVNAEYPLSEVTTVYAF-----GDV 347
Cdd:COG4773  207 NAAYEDGdSFRDG--VDNRRTLIAPSlDWDLTDDTT------------------LTLGAEYQDDDSTGDRGFlpldgTLL 266
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 348 NIRKGTSYAlyrAPYwvsDPNNllheagTTYNGFQPTFETDifdnlgsiglrsnvfgFNADFSLTAGSNKVDYTV-GNSL 426
Cdd:COG4773  267 DLPRSTNLG---EPW---DYYD------TETTTLFAELEHR----------------FNDDWSLRANARYSDSDRdGRSA 318
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 427 NVSLGANSPT-----QFEAGGYTFSQLVGNADFSRTFD------KVTFGFGTEIRREQFEARAGQEESYVGGGAQSFPGL 495
Cdd:COG4773  319 YAYGAPDAATgtltrYASARDGDSRSDSLDANLNGKFEtgglehTLLVGADYSRYDSDSDSATAGTINIYNPVYGNLPEP 398
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 496 QPANALKETRSN-VGVYTTLDYDMSEAFLIGGSIRYENYSDFGDNISWKVSSR-------------YKLTNDVAIRASFS 561
Cdd:COG4773  399 DFDASDTDTTTRqTGLYAQDQISLTDRLSLLLGGRYDWYETDSTNRLGGSTTSyddsaftpraglvYDLTPGLSLYASYS 478
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 562 TGFRApalhqiylsniqtlvsGGRISNQGTFnnvdpaviglgvpkLDAEESQNIATGI---TFRSGANFSASLdfYHIKV 638
Cdd:COG4773  479 ESFEP----------------QSGADNNGNP--------------LDPETGKQYEAGVkgeLFDGRLNATLAV--FDITQ 526
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 639 RNRVLFsgevgfDGDDTTtnpveevlldnditsmkFFINAVNTITKGVDvvlnyknLEIgTGRL--GLNLASNIANTKID 716
Cdd:COG4773  527 KNVATT------DPDNPN-----------------FYVQVGEVRSRGVE-------LEL-SGELtpGLNLIAGYTYTDAK 575
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517 717 gkigtpailsangYDIFNRKEQGRILSARPNTKVLLGMNYDLnkTTFIFNNTYFG-EVTWQ--HATDVAKDQTFAGKVIT 793
Cdd:COG4773  576 -------------ITKDADALEGKRLTNVPRHTASLWTTYRF--PSGALKGLGLGgGVRYVgeRYGDAANTFTLPSYTLV 640
                        650       660
                 ....*....|....*....|...
gi 515558517 794 DLGVAYNFTSTLSANVMVNNLLN 816
Cdd:COG4773  641 DAGARYDLGKNWTLQLNVNNLFD 663
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
116-816 7.64e-07

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 52.80  E-value: 7.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  116 AEDLKSSGQVTFDKMLAYKIPSFNSSSQAISDatahFDPADLRGLGPSrtlVLVNGkrknqsalVYINDTPGKGEVGTDm 195
Cdd:TIGR01783  11 RQELEDQQAGSLSEALQRVPGVVVGGSGGTTQ----FGNITIRGFGLE---VDIDN--------VYLDGVPLLSRGNLA- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  196 kSIPFSAIERVEVLRDGASAQYGSDAIAGVVNIILKK--QTNFTEVSLTSGVtsqGDGFNFGADLNSgfKIADKGFVNFN 273
Cdd:TIGR01783  75 -IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRpqDEPKGSVTFGAGT---RSGYRTAFDLGG--PLGADGTFRGR 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  274 ISYLAQnktnragkpgkddlfgvaaDDAQWGDWLSRNPDLGMT-IGLPDSKMGAFVVNAEYPLSEVTTVYafGDVNIRKG 352
Cdd:TIGR01783 149 LNGARQ-------------------DGDSFYDGAGEETRLGATaTDWQLDDRTLLRLGAYYQKERDRGGY--GGLPASGG 207
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  353 TSYALYRAPYWVSDPNN-------LLHEAGTTYNGFQPTF---ETDIFDNLGSIGLRSNVFGFNADFSLTAGSNKVDYTV 422
Cdd:TIGR01783 208 TSGRDLSSDRYLGTSSNrnyddreYLSYGLSLEYQFNDVWtgkQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVK 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  423 GNSLNVSLGANSPtqFEAGGYTFSQLVGNADFSRTFDK--VTFGFGTEIRREqfearagqeesyvggGAQSFPGLQPANA 500
Cdd:TIGR01783 288 QDRVQIDAGLDGE--FETGPIEHDLLLGVSYGQRTTNRfnNTGYPSDNIYSL---------------TATSSARTDIGDS 350
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  501 LKE------TRSNVGVYTTLDYDMSEAFLIGG----SIRYEN--------YSDFGDNISWKVSSRYKLTNDVAIRASFST 562
Cdd:TIGR01783 351 PKDralsstTKALNGVALQRILLADKWTLTLGgrydSVDVKSnngvagstGKRDDSQFTPSLGVAYKPTDDWSLYASYAE 430
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  563 GFRAPALHQIylsniqtlvsgGRISNQGtfnnvdpaviglgvpKLDAEESQNIATGITFRSGANFSASLDFYHIKVRNrv 642
Cdd:TIGR01783 431 SFKPGGYYPK-----------GAGNSGD---------------ILEPEKGKNYELGVRYDLGDSLLATAALFRITKDN-- 482
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  643 lfsgevgfdgddtttnpveevLLDNDitsmkffiNAVNTITKGVDVVLNYkNLEIGT-GRL--GLNLASNIANTKidgki 719
Cdd:TIGR01783 483 ---------------------QLVQD--------PVNGTFSVNAGKTRNR-GVELEArGYLtpGLSLSAGYTYTD----- 527
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517  720 gtpailsANGYDIFNRKEQGRILSARPNTKVLLGMNYDLNktTFIFNNTYFGEVTWQHATDVAKDQTF--AGKVITDLGV 797
Cdd:TIGR01783 528 -------AEFTEDTNGDTQGNTVPFVPKHTASLWASYAPP--VGDNGLTLGGGVQYTGKAYVDGGNTGkvPSYTVVDLSV 598
                         730       740
                  ....*....|....*....|.
gi 515558517  798 AYNFTS--TLSANVMVNNLLN 816
Cdd:TIGR01783 599 RYDLTKkkNLTLALNVNNLFD 619
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
12-66 2.07e-05

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 43.42  E-value: 2.07e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 515558517   12 TIKGIVTDENGQPLPYSNV----IEKETSNGVTTDGNGNFEIK-VKGFPVTLIAKYVGFQ 66
Cdd:pfam13620   1 TISGTVTDPSGAPVPGATVtvtnTDTGTVRTTTTDADGRYRFPgLPPGTYTVTVSAPGFK 60
PRK14050 PRK14050
TonB-dependent siderophore receptor;
199-275 2.79e-04

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 44.79  E-value: 2.79e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515558517 199 PFsAIERVEVLRDGASAQYGSDAIAGVVNIILKKQTNFTEVSLTSGVTSQGDGFnFGADLNSgfKIADKGFVNFNIS 275
Cdd:PRK14050 155 PF-MLERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDEPLYYTEIGINSYGNAF-TGFDVGD--KLSDDGTVRYRVT 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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