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Conserved domains on  [gi|515475014|ref|WP_016910859|]
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50S ribosomal protein L11 methyltransferase [Mammaliicoccus vitulinus]

Protein Classification

50S ribosomal protein L11 methyltransferase( domain architecture ID 11455142)

50S ribosomal protein L11 methyltransferase is a class I SAM-dependent methyltransferase that methylates ribosomal protein L11 using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-310 1.37e-112

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 327.13  E-value: 1.37e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   1 MNWIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELEKEHIdvygeiyelnpkdypehdiRVKCYFNELVFTDSLEQE 80
Cdd:COG2264    1 MKWIELTITTPEEAAEALSDALEELGAEGVEIEDAPPGLWERV-------------------GVKAYFPEDEDLEELLAA 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  81 IKDSIAHVEGInseilSFSKTIIKESDWENEWKNYFHPFKASERFAIVPSWEEdtYDNQDDDLCIKLDPGMAFGTGDHPT 160
Cdd:COG2264   62 LAEALGELGAP-----EITVEEVEEEDWVEEWKKYFKPIRVGDRLVIVPSWEE--YEPDPGEIVIEIDPGMAFGTGTHPT 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLteETEQ 240
Cdd:COG2264  135 TRLCLEALEKLLKPGKTVLDVGCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLL--EDGP 212

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYTIEKVLREDGWVSIRARK 310
Cdd:COG2264  213 YDLVVANILANPLIELAPDLAALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRK 282
 
Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-310 1.37e-112

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 327.13  E-value: 1.37e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   1 MNWIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELEKEHIdvygeiyelnpkdypehdiRVKCYFNELVFTDSLEQE 80
Cdd:COG2264    1 MKWIELTITTPEEAAEALSDALEELGAEGVEIEDAPPGLWERV-------------------GVKAYFPEDEDLEELLAA 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  81 IKDSIAHVEGInseilSFSKTIIKESDWENEWKNYFHPFKASERFAIVPSWEEdtYDNQDDDLCIKLDPGMAFGTGDHPT 160
Cdd:COG2264   62 LAEALGELGAP-----EITVEEVEEEDWVEEWKKYFKPIRVGDRLVIVPSWEE--YEPDPGEIVIEIDPGMAFGTGTHPT 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLteETEQ 240
Cdd:COG2264  135 TRLCLEALEKLLKPGKTVLDVGCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLL--EDGP 212

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYTIEKVLREDGWVSIRARK 310
Cdd:COG2264  213 YDLVVANILANPLIELAPDLAALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRK 282
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 2-310 3.21e-107

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 313.82  E-value: 3.21e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014    2 NWIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELEKEHIDVYGEIYELNPKDypehdIRVKCYFNElvftdslEQEI 81
Cdd:pfam06325   1 TWLELSIHTTREAAEPVSNILEEFGALGVAIEDADLLEDRDIFEPGLGEERLWDE-----VRVKALFDE-------ETDA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   82 KDSIAHVEGINSEILSFSKTI--IKESDWENEWKNYFHPFKASERFAIVPSWEEdtYDNQDDDLCIKLDPGMAFGTGDHP 159
Cdd:pfam06325  69 LELIAQLAELIGGLDSPKVTVeeVAEEDWARAWKKYFHPVRIGERLTIVPSWED--YPENPDALNIELDPGMAFGTGTHP 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  160 TTSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCE-QDILAETGNLLteeT 238
Cdd:pfam06325 147 TTKLCLEALERLVKPGESVLDVGCGSGILAIAALKLGAKKVVGVDIDPVAVRAAKENAELNGVEaRLEVYLPGDLP---K 223

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515475014  239 EQYDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKEtGYTIEKVLREDGWVSIRARK 310
Cdd:pfam06325 224 EKADVVVANILADPLIELAPDIYALVKPGGYLILSGILKEQAQMVAEAYSQ-GFELITVEHREEWVCIVGKK 294
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
1-310 1.67e-100

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 295.14  E-value: 1.67e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   1 MNWIEYSIMINKEAEPVVTALLNELGANgvviedsselekehidvygeiyelnpkdypehdirvkcyfnelvftDSLEQE 80
Cdd:PRK00517   1 MKWIELTLNTTPEAAEALSDILMELGAL----------------------------------------------AALANL 34

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  81 IKdsiahvEGINSEILSFSKTIIKESDWENEWKNYFHPFKASERFAIVPSWEEDTYDnqdDDLCIKLDPGMAFGTGDHPT 160
Cdd:PRK00517  35 AG------LGLDLGEPTYTIEEVEDEDWEREWKKYFHPIRIGDRLWIVPSWEDPPDP---DEINIELDPGMAFGTGTHPT 105

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLlteeteQ 240
Cdd:PRK00517 106 TRLCLEALEKLVLPGKTVLDVGCGSGILAIAAAKLGAKKVLAVDIDPQAVEAARENAELNGVELNVYLPQGDL------K 179

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYTIEKVLREDGWVSIRARK 310
Cdd:PRK00517 180 ADVIVANILANPLLELAPDLARLLKPGGRLILSGILEEQADEVLEAYEEAGFTLDEVLERGEWVALVGKK 249
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 3-304 4.51e-64

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 203.53  E-value: 4.51e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014    3 WIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELekehidvygeIYeLNPkDYPEHDIRVKCYfNELVFTDSLEQEIK 82
Cdd:TIGR00406   1 WIEIRINTTKELAEATSDALEEAGAVGVTFEDDKDT----------IY-FEP-HLPGEKRLWGNL-DVIALFDAETDMNN 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   83 DSIAHVEGINSEILSFSKTIIKES--DWENEWKNYFHPFKASERFAIVPSWEEDTYDnqDDDLCIKLDPGMAFGTGDHPT 160
Cdd:TIGR00406  68 SVIPLLEAFCLDLGRNHKIEFDEFskDWERAWKDNFHPVQFGKRFWICPSWRDVPSD--EDALIIMLDPGLAFGTGTHPT 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLTEETEQ 240
Cdd:TIGR00406 146 TSLCLEWLEDLDLKDKNVIDVGCGSGILSIAALKLGAAKVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQPIEGK 225

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515475014  241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLkETGYTIEKVLREDGWV 304
Cdd:TIGR00406 226 ADVIVANILAEVIKELYPQFSRLVKPGGWLILSGILETQAQSVCDAY-EQGFTVVEIRQREEWC 288
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 177-273 2.52e-06

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 45.50  E-value: 2.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 177 KIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKEN---FEKNNCE---QDILAetgnLLTEETEQYDVIIVNILA 250
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAaaaLLADNVEvlkGDAEE----LPPEADESFDVIISDPPL 76

                         90       100
                 ....*....|....*....|....*..
gi 515475014 251 HI----IDLMIEDSYARLNDNGYFITS 273
Cdd:cd02440   77 HHlvedLARFLEEARRLLKPGGVLVLT 103
 
Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-310 1.37e-112

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 327.13  E-value: 1.37e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   1 MNWIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELEKEHIdvygeiyelnpkdypehdiRVKCYFNELVFTDSLEQE 80
Cdd:COG2264    1 MKWIELTITTPEEAAEALSDALEELGAEGVEIEDAPPGLWERV-------------------GVKAYFPEDEDLEELLAA 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  81 IKDSIAHVEGInseilSFSKTIIKESDWENEWKNYFHPFKASERFAIVPSWEEdtYDNQDDDLCIKLDPGMAFGTGDHPT 160
Cdd:COG2264   62 LAEALGELGAP-----EITVEEVEEEDWVEEWKKYFKPIRVGDRLVIVPSWEE--YEPDPGEIVIEIDPGMAFGTGTHPT 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLteETEQ 240
Cdd:COG2264  135 TRLCLEALEKLLKPGKTVLDVGCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLL--EDGP 212

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYTIEKVLREDGWVSIRARK 310
Cdd:COG2264  213 YDLVVANILANPLIELAPDLAALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRK 282
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 2-310 3.21e-107

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 313.82  E-value: 3.21e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014    2 NWIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELEKEHIDVYGEIYELNPKDypehdIRVKCYFNElvftdslEQEI 81
Cdd:pfam06325   1 TWLELSIHTTREAAEPVSNILEEFGALGVAIEDADLLEDRDIFEPGLGEERLWDE-----VRVKALFDE-------ETDA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   82 KDSIAHVEGINSEILSFSKTI--IKESDWENEWKNYFHPFKASERFAIVPSWEEdtYDNQDDDLCIKLDPGMAFGTGDHP 159
Cdd:pfam06325  69 LELIAQLAELIGGLDSPKVTVeeVAEEDWARAWKKYFHPVRIGERLTIVPSWED--YPENPDALNIELDPGMAFGTGTHP 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  160 TTSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCE-QDILAETGNLLteeT 238
Cdd:pfam06325 147 TTKLCLEALERLVKPGESVLDVGCGSGILAIAALKLGAKKVVGVDIDPVAVRAAKENAELNGVEaRLEVYLPGDLP---K 223

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515475014  239 EQYDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKEtGYTIEKVLREDGWVSIRARK 310
Cdd:pfam06325 224 EKADVVVANILADPLIELAPDIYALVKPGGYLILSGILKEQAQMVAEAYSQ-GFELITVEHREEWVCIVGKK 294
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
1-310 1.67e-100

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 295.14  E-value: 1.67e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   1 MNWIEYSIMINKEAEPVVTALLNELGANgvviedsselekehidvygeiyelnpkdypehdirvkcyfnelvftDSLEQE 80
Cdd:PRK00517   1 MKWIELTLNTTPEAAEALSDILMELGAL----------------------------------------------AALANL 34

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  81 IKdsiahvEGINSEILSFSKTIIKESDWENEWKNYFHPFKASERFAIVPSWEEDTYDnqdDDLCIKLDPGMAFGTGDHPT 160
Cdd:PRK00517  35 AG------LGLDLGEPTYTIEEVEDEDWEREWKKYFHPIRIGDRLWIVPSWEDPPDP---DEINIELDPGMAFGTGTHPT 105

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLlteeteQ 240
Cdd:PRK00517 106 TRLCLEALEKLVLPGKTVLDVGCGSGILAIAAAKLGAKKVLAVDIDPQAVEAARENAELNGVELNVYLPQGDL------K 179

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYTIEKVLREDGWVSIRARK 310
Cdd:PRK00517 180 ADVIVANILANPLLELAPDLARLLKPGGRLILSGILEEQADEVLEAYEEAGFTLDEVLERGEWVALVGKK 249
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 3-304 4.51e-64

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 203.53  E-value: 4.51e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014    3 WIEYSIMINKEAEPVVTALLNELGANGVVIEDSSELekehidvygeIYeLNPkDYPEHDIRVKCYfNELVFTDSLEQEIK 82
Cdd:TIGR00406   1 WIEIRINTTKELAEATSDALEEAGAVGVTFEDDKDT----------IY-FEP-HLPGEKRLWGNL-DVIALFDAETDMNN 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014   83 DSIAHVEGINSEILSFSKTIIKES--DWENEWKNYFHPFKASERFAIVPSWEEDTYDnqDDDLCIKLDPGMAFGTGDHPT 160
Cdd:TIGR00406  68 SVIPLLEAFCLDLGRNHKIEFDEFskDWERAWKDNFHPVQFGKRFWICPSWRDVPSD--EDALIIMLDPGLAFGTGTHPT 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLTEETEQ 240
Cdd:TIGR00406 146 TSLCLEWLEDLDLKDKNVIDVGCGSGILSIAALKLGAAKVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQPIEGK 225

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515475014  241 YDVIIVNILAHIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLkETGYTIEKVLREDGWV 304
Cdd:TIGR00406 226 ADVIVANILAEVIKELYPQFSRLVKPGGWLILSGILETQAQSVCDAY-EQGFTVVEIRQREEWC 288
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
177-301 6.61e-13

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 66.08  E-value: 6.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 177 KIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLtEETEQYDVIIVN----ILAHI 252
Cdd:COG2263   48 TVLDLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIARENAERLGVRVDFIRADVTRI-PLGGSVDTVVMNppfgAQRRH 126

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 515475014 253 IDLMIEDSYARLNDNGYFITSgiieEKSDEIIEKL-KETGYTIEKVLRED 301
Cdd:COG2263  127 ADRPFLEKALEIAAVIYSIHN----AGSLDFVERFaADRGGEITHVFRAE 172
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 168-271 2.10e-12

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 63.11  E-value: 2.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 168 IEEVVKPNHKIIDVGTGSGILSIGCHLLGVQsIKAVDLDELAIKVAKENFEKNNCE---QDILAetgnlLTEETEQYDVI 244
Cdd:COG2227   18 LARLLPAGGRVLDVGCGTGRLALALARRGAD-VTGVDISPEALEIARERAAELNVDfvqGDLED-----LPLEDGSFDLV 91

                         90       100       110
                 ....*....|....*....|....*....|
gi 515475014 245 I-VNILAHIIDL--MIEDSYARLNDNGYFI 271
Cdd:COG2227   92 IcSEVLEHLPDPaaLLRELARLLKPGGLLL 121
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 168-310 1.34e-11

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 63.63  E-value: 1.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 168 IEEVVK-----PNHKIIDVGTGSGILSIGC--HLLGVQsIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLT--EET 238
Cdd:COG2890  101 VELALAllpagAPPRVLDLGTGSGAIALALakERPDAR-VTAVDISPDALAVARRNAERLGLEDRVRFLQGDLFEplPGD 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 239 EQYDVIIVN---ILAHIIDLM--------------------------IEDSYARLNDNGYFITsgiieeksdeiieklkE 289
Cdd:COG2890  180 GRFDLIVSNppyIPEDEIALLppevrdheprlaldggedgldfyrriIAQAPRLLKPGGWLLL----------------E 243

                        170       180
                 ....*....|....*....|....*
gi 515475014 290 TGYT----IEKVLREDGWVSIRARK 310
Cdd:COG2890  244 IGEDqgeaVRALLEAAGFADVETHK 268
PRK14968 PRK14968
putative methyltransferase; Provisional
 171-300 2.95e-11

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 61.45  E-value: 2.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 171 VVKPNHKIIDVGTGSGILSIGCHLLGVqSIKAVDLDELAIKVAKENFEKNNC-EQDILAETGNLLTE-ETEQYDVIIVN- 247
Cdd:PRK14968  20 VDKKGDRVLEVGTGSGIVAIVAAKNGK-KVVGVDINPYAVECAKCNAKLNNIrNNGVEVIRSDLFEPfRGDKFDVILFNp 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515475014 248 -------------ILAH----------IIDLMIEDSYARLNDNG--YFITSGIIEEksDEIIEKLKETGYTIEKVLRE 300
Cdd:PRK14968  99 pylpteeeeewddWLNYalsggkdgreVIDRFLDEVGRYLKPGGriLLLQSSLTGE--DEVLEYLEKLGFEAEVVAEE 174
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 146-268 1.39e-10

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 59.43  E-value: 1.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 146 KLDPGmafgtgdhptTSMCLKHIEEvvKPNHKIIDVGTGSGILSIGCHLLGVQ-SIKAVDLDELAIKVAKENFEKNNCEq 224
Cdd:COG2813   33 RLDIG----------TRLLLEHLPE--PLGGRVLDLGCGYGVIGLALAKRNPEaRVTLVDVNARAVELARANAAANGLE- 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 515475014 225 DILAETGNLLTE-ETEQYDVIIVN--------ILAHIIDLMIEDSYARLNDNG 268
Cdd:COG2813  100 NVEVLWSDGLSGvPDGSFDLILSNppfhagraVDKEVAHALIADAARHLRPGG 152
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 172-247 3.07e-10

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 59.39  E-value: 3.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 172 VKPNHKIIDVGTGSGILSIgchLL----GVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLT----EETEQYDV 243
Cdd:COG4123   35 VKKGGRVLDLGTGTGVIAL---MLaqrsPGARITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKEfaaeLPPGSFDL 111


                 ....
gi 515475014 244 IIVN 247
Cdd:COG4123  112 VVSN 115
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
168-266 3.12e-09

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 56.20  E-value: 3.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 168 IEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLT-EETEQYDVIIV 246
Cdd:COG4076   29 IERVVKPGDVVLDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSDRITVINADATDlDLPEKADVIIS 108

                         90       100
                 ....*....|....*....|
gi 515475014 247 NILAhiIDLMIEDSYARLND 266
Cdd:COG4076  109 EMLD--TALLDEGQVPILNH 126
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 146-268 4.20e-09

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 54.90  E-value: 4.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  146 KLDPGMAFgtgdhpttsmCLKHIEevVKPNHKIIDVGTGSGILSIGCHLL-GVQSIKAVDLDELAIKVAKENFEKNNCE- 223
Cdd:pfam05175  15 RLDIGSRL----------LLEHLP--KDLSGKVLDLGCGAGVLGAALAKEsPDAELTMVDINARALESARENLAANGLEn 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 515475014  224 -----QDILAETgnllteETEQYDVIIVN--------ILAHIIDLMIEDSYARLNDNG 268
Cdd:pfam05175  83 gevvaSDVYSGV------EDGKFDLIISNppfhaglaTTYNVAQRFIADAKRHLRPGG 134
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 172-293 1.70e-07

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 49.61  E-value: 1.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 172 VKPNHKIIDVGTGSGILSI-----GCHLLGvqsikaVDLDELAIKVAKENFEKNNCEQDILAETGNLLTEETEQYD-VII 245
Cdd:COG2226   20 LRPGARVLDLGCGTGRLALalaerGARVTG------VDISPEMLELARERAAEAGLNVEFVVGDAEDLPFPDGSFDlVIS 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 515475014 246 VNILAHIIDL--MIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYT 293
Cdd:COG2226   94 SFVLHHLPDPerALAEIARVLKPGGRLVVVDFSPPDLAELEELLAEAGFE 143
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 178-254 2.03e-07

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 48.33  E-value: 2.03e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515475014  178 IIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLTEETEQYDVIIVNILAHIID 254
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLP 77
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 177-310 2.48e-07

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 50.93  E-value: 2.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 177 KIIDVGTGSGI--LSIGCHLLGVQsIKAVDLDELAIKVAKENFEKNNCEQ-DILAetGNLLTE-ETEQYDVIIVN---IL 249
Cdd:PRK09328 111 RVLDLGTGSGAiaLALAKERPDAE-VTAVDISPEALAVARRNAKHGLGARvEFLQ--GDWFEPlPGGRFDLIVSNppyIP 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 250 AHIIDLMIEDsyARLND---------NGYFITSGIIEeksdEIIEKLK-------ETGYT----IEKVLREDGWVSIRAR 309
Cdd:PRK09328 188 EADIHLLQPE--VRDHEphlalfggeDGLDFYRRIIE----QAPRYLKpggwlllEIGYDqgeaVRALLAAAGFADVETR 261


                 .
gi 515475014 310 K 310
Cdd:PRK09328 262 K 262
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 136-271 8.16e-07

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 48.00  E-value: 8.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 136 YDNQDDDLCIKLDPGMAF--GTGDHPTTSM------CLKHIEE--VVKPNHKIIDVGTGSGILSI------GCHLLGvqs 199
Cdd:COG2230    3 YDLGNDFYRLFLDPTMTYscAYFEDPDDTLeeaqeaKLDLILRklGLKPGMRVLDIGCGWGGLALylarryGVRVTG--- 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515475014 200 ikaVDLDELAIKVAKENFEKNNCEQDILAETGNLL-TEETEQYDVII-VNILAHI----IDLMIEDSYARLNDNGYFI 271
Cdd:COG2230   80 ---VTLSPEQLEYARERAAEAGLADRVEVRLADYRdLPADGQFDAIVsIGMFEHVgpenYPAYFAKVARLLKPGGRLL 154
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 177-273 2.52e-06

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 45.50  E-value: 2.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 177 KIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKEN---FEKNNCE---QDILAetgnLLTEETEQYDVIIVNILA 250
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAaaaLLADNVEvlkGDAEE----LPPEADESFDVIISDPPL 76

                         90       100
                 ....*....|....*....|....*..
gi 515475014 251 HI----IDLMIEDSYARLNDNGYFITS 273
Cdd:cd02440   77 HHlvedLARFLEEARRLLKPGGVLVLT 103
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 171-297 1.25e-05

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 44.94  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 171 VVKPNHKIID--VGTGsGILsIGCHLLGVQSIkAVDLDELAIKVAKENFEKNNCEQ------DILAetgnlLTEETEQYD 242
Cdd:COG1041   23 GAKEGDTVLDpfCGTG-TIL-IEAGLLGRRVI-GSDIDPKMVEGARENLEHYGYEDadvirgDARD-----LPLADESVD 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515475014 243 VIIVN--------ILAHIIDLMIEDS----YARLNDNGY--FITsgiieekSDEIIEKLKETGYTIEKV 297
Cdd:COG1041   95 AIVTDppygrsskISGEELLELYEKAleeaARVLKPGGRvvIVT-------PRDIDELLEEAGFKVLER 156
hemK_fam TIGR00536
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme ...
 174-247 1.75e-05

HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase. Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair]


Pssm-ID: 273125 [Multi-domain]  Cd Length: 284  Bit Score: 45.42  E-value: 1.75e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515475014  174 PNHKIIDVGTGSGILSIGC-HLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETGNLLTE-ETEQYDVIIVN 247
Cdd:TIGR00536 114 PILHILDLGTGSGCIALALaYEFPNAEVIAVDISPDALAVAEENAEKNQLEHRVEFIQSNLFEPlAGQKIDIIVSN 189
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 177-274 4.61e-05

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 43.75  E-value: 4.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 177 KIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNC------EQDILaetgNLLTEETEQYDVIIVNILA 250
Cdd:COG0500   29 RVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLgnveflVADLA----ELDPLPAESFDLVVAFGVL 104

                         90       100
                 ....*....|....*....|....*....
gi 515475014 251 HIIDLMIEDSYAR-----LNDNGYFITSG 274
Cdd:COG0500  105 HHLPPEEREALLRelaraLKPGGVLLLSA 133
RlmK COG1092
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ...
 196-273 6.12e-05

23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440709 [Multi-domain]  Cd Length: 392  Bit Score: 44.02  E-value: 6.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 196 GVQSIKAVDLDELAIKVAKENFEKNNCEQ----------DILAEtgnlLTEETEQYDVIIV-------------NILAHI 252
Cdd:COG1092  238 GAKSVTSVDLSATALEWAKENAALNGLDDrhefvqadafDWLRE----LAREGERFDLIILdppafakskkdlfDAQRDY 313

                         90       100
                 ....*....|....*....|.
gi 515475014 253 IDLmIEDSYARLNDNGYFITS 273
Cdd:COG1092  314 KDL-NRLALKLLAPGGILVTS 333
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 177-295 1.67e-04

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 41.71  E-value: 1.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 177 KIIDVGTGSGILSIGCHLLGVQSIK--AVDLDELAIKVAKENFEK----NNCEQdILAETGNLLTEETEQYDVIIVNILA 250
Cdd:PRK00377  43 MILDIGCGTGSVTVEASLLVGETGKvyAVDKDEKAINLTRRNAEKfgvlNNIVL-IKGEAPEILFTINEKFDRIFIGGGS 121

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 515475014 251 HIIDLMIEDSYARLNDNGYFITSGIIEEKSDEIIEKLKETGYTIE 295
Cdd:PRK00377 122 EKLKEIISASWEIIKKGGRIVIDAILLETVNNALSALENIGFNLE 166
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
174-271 1.81e-04

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 39.81  E-value: 1.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 174 PNHKIIDVGTGSGILS-------IGCHLLGvqsikaVDLDELAIKVAKENFEknnceqDILAETGNLLT-EETEQYDVII 245
Cdd:COG4106    1 PPRRVLDLGCGTGRLTallaerfPGARVTG------VDLSPEMLARARARLP------NVRFVVADLRDlDPPEPFDLVV 68

                         90       100
                 ....*....|....*....|....*....
gi 515475014 246 VN-ILAHIIDL--MIEDSYARLNDNGYFI 271
Cdd:COG4106   69 SNaALHWLPDHaaLLARLAAALAPGGVLA 97
Trm5 COG2520
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ...
 168-295 3.26e-04

tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442010 [Multi-domain]  Cd Length: 333  Bit Score: 41.77  E-value: 3.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 168 IEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILAETG---NLLTEETEQYDVI 244
Cdd:COG2520  174 IAELVKPGERVLDMFAGVGPFSIPIAKRSGAKVVAIDINPDAVEYLKENIRLNKVEDRVTPILGdarEVAPELEGKADRI 253

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 515475014 245 IVNiLAHIIDLMIEDSYARLNDNG---YFIT---SGIIEEKSDEIIEKLKETGYTIE 295
Cdd:COG2520  254 IMN-LPHSADEFLDAALRALKPGGvihYYEIvpeEDPFERAEERIEEAAEEAGYEVE 309
SpeE COG0421
Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];
181-272 3.37e-04

Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];


Pssm-ID: 440190 [Multi-domain]  Cd Length: 195  Bit Score: 40.97  E-value: 3.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 181 VGTGSGILSIGCH-LLGVQSIKAVDLDELAIKVAKENFEKNNCEQD-----ILAETG-NLLTEETEQYDVIIVNILAHI- 252
Cdd:COG0421   44 IGGGDGGLARELLkHPPVERVDVVEIDPEVVELAREYFPLLAPAFDdprlrVVIGDGrAFLREAEESYDVIIVDLTDPVg 123

                         90       100
                 ....*....|....*....|....*.
gi 515475014 253 --IDLM----IEDSYARLNDNGYFIT 272
Cdd:COG0421  124 paEGLFtrefYEDCRRALKPGGVLVV 149
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 173-273 4.08e-04

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 40.09  E-value: 4.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  173 KPNHKIIDVGTGSGILSIGCHLLGVQSIK--AVDLDELAIKVAKENFEKNN------CEQDILAETGNLlteETEQYDVI 244
Cdd:pfam13847   2 DKGMRVLDLGCGTGHLSFELAEELGPNAEvvGIDISEEAIEKARENAQKLGfdnvefEQGDIEELPELL---EDDKFDVV 78

                          90       100       110
                  ....*....|....*....|....*....|..
gi 515475014  245 IVN-ILAHIIDL-MIEDSYAR-LNDNGYFITS 273
Cdd:pfam13847  79 ISNcVLNHIPDPdKVLQEILRvLKPGGRLIIS 110
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 177-271 7.86e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 39.33  E-value: 7.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014  177 KIIDVGTGSGILSIGCHLLGVqSIKAVDLDELAIKVAKENFEKNN-CEQDILAETGnllteeteQYDVIIVN-ILAHIID 254
Cdd:pfam13489  25 RVLDFGCGTGIFLRLLRAQGF-SVTGVDPSPIAIERALLNVRFDQfDEQEAAVPAG--------KFDVIVAReVLEHVPD 95

                          90
                  ....*....|....*....
gi 515475014  255 L--MIEDSYARLNDNGYFI 271
Cdd:pfam13489  96 PpaLLRQIAALLKPGGLLL 114
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 172-247 2.28e-03

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 38.53  E-value: 2.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 172 VKPNHKIIDVGTGSG----ILSigcHLlgVQSIKAVDLD-ELAIKvAKENFEKNNCEqDILAETGNLLT--EETEQYDVI 244
Cdd:COG2518   64 LKPGDRVLEIGTGSGyqaaVLA---RL--AGRVYSVERDpELAER-ARERLAALGYD-NVTVRVGDGALgwPEHAPFDRI 136


                 ...
gi 515475014 245 IVN 247
Cdd:COG2518  137 IVT 139
PRK14967 PRK14967
putative methyltransferase; Provisional
 168-247 3.75e-03

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 38.11  E-value: 3.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 168 IEEVVKPNHKIIDVGTGSGILSIGCHLLGVQSIKAVDLDELAIKVAKENFEKNNCEQDILaeTGNLLTE-ETEQYDVIIV 246
Cdd:PRK14967  30 AAEGLGPGRRVLDLCTGSGALAVAAAAAGAGSVTAVDISRRAVRSARLNALLAGVDVDVR--RGDWARAvEFRPFDVVVS 107


                 .
gi 515475014 247 N 247
Cdd:PRK14967 108 N 108
TRM1 COG1867
tRNA G26 N,N-dimethylase Trm1 [Translation, ribosomal structure and biogenesis]; tRNA G26 N, ...
 161-244 9.91e-03

tRNA G26 N,N-dimethylase Trm1 [Translation, ribosomal structure and biogenesis]; tRNA G26 N,N-dimethylase Trm1 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441472  Cd Length: 383  Bit Score: 37.16  E-value: 9.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515475014 161 TSMCLKHIEEVVKPNHKIIDVGTGSGILSIGCHL-LGVQSIkAVDLDELAIKVAKENFEKNNCEQ-DILAETGN-LLTEE 237
Cdd:COG1867   44 SVAALRAYRERLKREISYLDALAASGIRGLRYALeVGIKVT-LNDIDPEAVELIRENLELNGLEDvEVYNRDANaLLHEL 122


                 ....*..
gi 515475014 238 TEQYDVI 244
Cdd:COG1867  123 GRRFDVV 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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