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Conserved domains on  [gi|512738910|ref|WP_016496633|]
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recombination regulator RecX [Limosilactobacillus reuteri]

Protein Classification

regulatory protein RecX( domain architecture ID 10014591)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-264 3.77e-118

recombination regulator RecX; Provisional


:

Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 338.73  E-value: 3.77e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910   4 ISKIEAQKR-KGRYNIYLDGKYAFPVAESVLIQFRLMKGTELDEKQIAAIATADQQAKAYSRMLDYLSYQMRTESDIVKK 82
Cdd:PRK14135   1 ITKITVQKKnKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  83 LKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAELAKK 162
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910 163 LARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSVYEMIKDEVVPQPDLEQENDLLAKEAAKQWRRVRRYQGYEREQHFKQ 242
Cdd:PRK14135 161 LAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQ 240
                        250       260
                 ....*....|....*....|..
gi 512738910 243 TMYRKGFDLDDVQSWLDAQDFQ 264
Cdd:PRK14135 241 ALYRKGFSYDDIDSFLREYGIE 262
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-264 3.77e-118

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 338.73  E-value: 3.77e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910   4 ISKIEAQKR-KGRYNIYLDGKYAFPVAESVLIQFRLMKGTELDEKQIAAIATADQQAKAYSRMLDYLSYQMRTESDIVKK 82
Cdd:PRK14135   1 ITKITVQKKnKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  83 LKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAELAKK 162
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910 163 LARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSVYEMIKDEVVPQPDLEQENDLLAKEAAKQWRRVRRYQGYEREQHFKQ 242
Cdd:PRK14135 161 LAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQ 240
                        250       260
                 ....*....|....*....|..
gi 512738910 243 TMYRKGFDLDDVQSWLDAQDFQ 264
Cdd:PRK14135 241 ALYRKGFSYDDIDSFLREYGIE 262
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
55-196 5.42e-39

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 132.99  E-value: 5.42e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  55 ADQQAKAYSRMLDYLSYQMRTESDIVKKLKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHL 134
Cdd:COG2137    2 EDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQEL 81
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512738910 135 RQKGIGENDIDDALTQFTPEVQAELAKKLARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSV 196
Cdd:COG2137   82 RQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDL 143
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
83-203 3.52e-35

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 122.31  E-value: 3.52e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910   83 LKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAelAKK 162
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 512738910  163 LARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSVYEMIKDE 203
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQE 119
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-264 3.77e-118

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 338.73  E-value: 3.77e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910   4 ISKIEAQKR-KGRYNIYLDGKYAFPVAESVLIQFRLMKGTELDEKQIAAIATADQQAKAYSRMLDYLSYQMRTESDIVKK 82
Cdd:PRK14135   1 ITKITVQKKnKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  83 LKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAELAKK 162
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910 163 LARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSVYEMIKDEVVPQPDLEQENDLLAKEAAKQWRRVRRYQGYEREQHFKQ 242
Cdd:PRK14135 161 LAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQ 240
                        250       260
                 ....*....|....*....|..
gi 512738910 243 TMYRKGFDLDDVQSWLDAQDFQ 264
Cdd:PRK14135 241 ALYRKGFSYDDIDSFLREYGIE 262
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
55-196 5.42e-39

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 132.99  E-value: 5.42e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  55 ADQQAKAYSRMLDYLSYQMRTESDIVKKLKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHL 134
Cdd:COG2137    2 EDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQEL 81
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512738910 135 RQKGIGENDIDDALTQFTPEVQAELAKKLARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSV 196
Cdd:COG2137   82 RQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDL 143
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
83-203 3.52e-35

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 122.31  E-value: 3.52e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910   83 LKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDLKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAelAKK 162
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 512738910  163 LARKLFRRYRNQPERRRQQKVQQGLMIKGFSSSVYEMIKDE 203
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQE 119
recX PRK00117
recombination regulator RecX; Reviewed
51-202 6.92e-24

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 94.18  E-value: 6.92e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  51 AIATADQQAKAYSRMLDYLSYQMRTESDIVKKLKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTDlKGPGVI 130
Cdd:PRK00117   3 DTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRARKG-YGPRRI 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512738910 131 RQHLRQKGIGENDIDDALTQFTPEvQAELAKKLARKLFRRYRNQPERRRqQKVQQGLMIKGFSssvYEMIKD 202
Cdd:PRK00117  82 RQELRQKGVDREIIEEALAELDID-WEELARELARKKFRRPLPDDAKEK-AKLVRFLARRGFS---MDVIQR 148
recX PRK14134
recombination regulator RecX; Provisional
3-224 2.75e-21

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 90.25  E-value: 2.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910   3 KISKIEAQKR-KGRYNIYLDGKYAFPVAESVLIQFRLMKGTELDEKQIAAIATADQQAKAYSRMLDYLSYQMRTESDIVK 81
Cdd:PRK14134   4 IITKIEVQKRnKDRVNVYIDEEFAFACSAELVYYHNLKKGKVIDVNSLNDIIKEDNYIKCKGYALKYIEKSYKTEKQIKE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  82 KLKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTMINTdlKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAELAK 161
Cdd:PRK14134  84 KLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIREKINS--YGRNKIKYTLLNKGIKENIIIEKINNIDEEKEKKVAY 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 512738910 162 KLARKLFRRYRNQPERRRQ--QKVQQGLMIKGFSSSVYEMIKDEVVPQPDLEQENDLLAKEAAKQ 224
Cdd:PRK14134 162 KLAEKKYKILILSEKNKFKiyKKLGPYLISRGYSSNIAEWILNELIKNEALYKDNNSQNIENNIK 226
recX PRK14136
recombination regulator RecX; Provisional
64-195 3.13e-03

recombination regulator RecX; Provisional


Pssm-ID: 237620 [Multi-domain]  Cd Length: 309  Bit Score: 38.44  E-value: 3.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512738910  64 RMLDYLSYQMRTESDIVKKLKEIDTPEEFIEPILKKLRDQQLIDDHAYAASYVRTmiNTDLKGPGVIRQHLRQKGIGEND 143
Cdd:PRK14136 167 RALGYLSRREYSRAELARKLAPYADESDSVEPLLDALEREGWLSDARFAESLVHR--RASRVGSARIVSELKRHAVGDAL 244
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 512738910 144 IDDALTQFTpEVQAELAKKLARKLFRRYRNQPERRRQQKvqQGLMIKGFSSS 195
Cdd:PRK14136 245 VESVGAQLR-ETEFERAQAVWRKKFGALPQTPAERAKQA--RFLAARGFSSA 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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