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Conserved domains on  [gi|510904440|ref|WP_016232090|]
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DUF1471 family protein YdgH [Escherichia coli]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-314 0e+00

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


:

Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 553.16  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440   1 MKLKNTLLASALLSATA--FSVNAATELTPEQAAAVKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGN 78
Cdd:NF040471   1 MKLKNTILASALLLSLTalSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIQDTNDVNN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440  79 SGNWRVVADLYKADAEKAEE-TSNRVINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQ 157
Cdd:NF040471  81 SGNWRVTADLYHKDAPKADKdPKYRVFNGVKELPKDEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFFIVRQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440 158 IDANQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEATKKVEIPGVATTASPSSEVGRFFETQSSKGGR 237
Cdd:NF040471 161 VDANSGGNQSITAYIYKADAPKRVVQSPDVIPADSDAGRAALAAGGAAAKKVEIPGVASSESPSSKVGRFFETQSSTGGR 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 510904440 238 YTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTEVSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK 314
Cdd:NF040471 241 YTVTLPDGTKIEEVNNITAAQMVPFDSITFTGHFSSMTDVSYQVAKRAAKKGAKYYHITRQWQSNGGNLTISADLFK 317
 
Name Accession Description Interval E-value
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-314 0e+00

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 553.16  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440   1 MKLKNTLLASALLSATA--FSVNAATELTPEQAAAVKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGN 78
Cdd:NF040471   1 MKLKNTILASALLLSLTalSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIQDTNDVNN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440  79 SGNWRVVADLYKADAEKAEE-TSNRVINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQ 157
Cdd:NF040471  81 SGNWRVTADLYHKDAPKADKdPKYRVFNGVKELPKDEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFFIVRQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440 158 IDANQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEATKKVEIPGVATTASPSSEVGRFFETQSSKGGR 237
Cdd:NF040471 161 VDANSGGNQSITAYIYKADAPKRVVQSPDVIPADSDAGRAALAAGGAAAKKVEIPGVASSESPSSKVGRFFETQSSTGGR 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 510904440 238 YTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTEVSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK 314
Cdd:NF040471 241 YTVTLPDGTKIEEVNNITAAQMVPFDSITFTGHFSSMTDVSYQVAKRAAKKGAKYYHITRQWQSNGGNLTISADLFK 317
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 118-173 9.06e-15

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 67.55  E-value: 9.06e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 510904440  118 IEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDANqGGNQRITAFIY 173
Cdd:pfam07338   1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADEPN-GGNWHGTAELY 55
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-90 1.46e-11

peroxide/acid stress response protein YhcN;


Pssm-ID: 411360  Cd Length: 87  Bit Score: 59.66  E-value: 1.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440   1 MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSdfgNSG 80
Cdd:NF033776   1 MKIKTTIAALSLLSVLSFGAFAAQSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEAR---NGG 77

                         90
                 ....*....|
gi 510904440  81 NWRVVADLYK 90
Cdd:NF033776  78 NWHATAELYK 87
 
Name Accession Description Interval E-value
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-314 0e+00

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 553.16  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440   1 MKLKNTLLASALLSATA--FSVNAATELTPEQAAAVKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGN 78
Cdd:NF040471   1 MKLKNTILASALLLSLTalSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIQDTNDVNN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440  79 SGNWRVVADLYKADAEKAEE-TSNRVINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQ 157
Cdd:NF040471  81 SGNWRVTADLYHKDAPKADKdPKYRVFNGVKELPKDEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFFIVRQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440 158 IDANQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEATKKVEIPGVATTASPSSEVGRFFETQSSKGGR 237
Cdd:NF040471 161 VDANSGGNQSITAYIYKADAPKRVVQSPDVIPADSDAGRAALAAGGAAAKKVEIPGVASSESPSSKVGRFFETQSSTGGR 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 510904440 238 YTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTEVSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK 314
Cdd:NF040471 241 YTVTLPDGTKIEEVNNITAAQMVPFDSITFTGHFSSMTDVSYQVAKRAAKKGAKYYHITRQWQSNGGNLTISADLFK 317
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 118-173 9.06e-15

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 67.55  E-value: 9.06e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 510904440  118 IEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDANqGGNQRITAFIY 173
Cdd:pfam07338   1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADEPN-GGNWHGTAELY 55
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 34-89 1.21e-14

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 67.16  E-value: 1.21e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 510904440   34 VKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSDfGNSGNWRVVADLY 89
Cdd:pfam07338   1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADE-PNGGNWHGTAELY 55
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-90 1.46e-11

peroxide/acid stress response protein YhcN;


Pssm-ID: 411360  Cd Length: 87  Bit Score: 59.66  E-value: 1.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510904440   1 MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSdfgNSG 80
Cdd:NF033776   1 MKIKTTIAALSLLSVLSFGAFAAQSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEAR---NGG 77

                         90
                 ....*....|
gi 510904440  81 NWRVVADLYK 90
Cdd:NF033776  78 NWHATAELYK 87
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 259-313 9.74e-10

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 53.68  E-value: 9.74e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 510904440  259 MVPFDSIKFSGNYGNMTEVSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLY 313
Cdd:pfam07338   1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADEPNGGNWHGTAELY 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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