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Conserved domains on  [gi|507089251|ref|WP_016159966|]
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MULTISPECIES: archaetidylserine decarboxylase [Escherichia]

Protein Classification

phosphatidylserine decarboxylase( domain architecture ID 10011131)

phosphatidylserine decarboxylase catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)

EC:  4.1.1.65
Gene Ontology:  GO:0006646|GO:0004609
PubMed:  1495415|32402247|33707636
SCOP:  4007787

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 1-289 0e+00

phosphatidylserine decarboxylase; Reviewed


:

Pssm-ID: 234591  Cd Length: 288  Bit Score: 582.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   1 MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMQEAQKPDTASYRTFNEFFVRPLRDEVRPIDT 80
Cdd:PRK00044   1 MLDRLKILLQYLLPKHLLTRLAGWLASSRAGWLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  81 DPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV 160
Cdd:PRK00044  81 DPNALVSPADGAISQLGPIEDGQIFQAKGHSYSLEALLGGDAALADPFRNGSFATIYLSPRDYHRVHMPCDGTLREMIYV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 161 PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPaGENDGSVA 240
Cdd:PRK00044 161 PGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIETVWAGTVTPPREGIIKRWDYP-EAGDGAIT 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 507089251 241 LLKGQEMGRFKLGSTVINLFAPGKVNLVEQLASLSVTKIGQPLAVSTEP 289
Cdd:PRK00044 240 LKKGAEMGRFKLGSTVINLFPPGKVQLAEQLQAGSVVRMGQPLAHITET 288
 
Name Accession Description Interval E-value
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 1-289 0e+00

phosphatidylserine decarboxylase; Reviewed


Pssm-ID: 234591  Cd Length: 288  Bit Score: 582.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   1 MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMQEAQKPDTASYRTFNEFFVRPLRDEVRPIDT 80
Cdd:PRK00044   1 MLDRLKILLQYLLPKHLLTRLAGWLASSRAGWLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  81 DPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV 160
Cdd:PRK00044  81 DPNALVSPADGAISQLGPIEDGQIFQAKGHSYSLEALLGGDAALADPFRNGSFATIYLSPRDYHRVHMPCDGTLREMIYV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 161 PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPaGENDGSVA 240
Cdd:PRK00044 161 PGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIETVWAGTVTPPREGIIKRWDYP-EAGDGAIT 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 507089251 241 LLKGQEMGRFKLGSTVINLFAPGKVNLVEQLASLSVTKIGQPLAVSTEP 289
Cdd:PRK00044 240 LKKGAEMGRFKLGSTVINLFPPGKVQLAEQLQAGSVVRMGQPLAHITET 288
PS_decarb TIGR00163
phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as ...
 49-287 3.72e-140

phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 272936 [Multi-domain]  Cd Length: 238  Bit Score: 395.74  E-value: 3.72e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   49 MQEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLF 128
Cdd:TIGR00163   1 LDEAEKPDLADYRSLNEFFIRPLKLERRPVDKEPNALVSPADGVISEVGIINPNQILQVKGMDYSLEELLGEKNPLSPYF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  129 RNGT-FVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVG 207
Cdd:TIGR00163  81 RNGGfFVVTYLSPRDYHRFHSPCDCRLRKMRYFPGDLFSVNPLGLQNVPNLFVRNERVILVFDTEFGNMLMIPVGATNVG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  208 SIETVWAGTITP-PREGIIKRWTWPAgenDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLASLSVTKIGQPLAVS 286
Cdd:TIGR00163 161 SIRTNFDGNIQTnPRHEFTQTWTYNA---LGPVKLLKGEEMGYFELGSTVILLFEADAFQLSAHLAVGQEVKIGELLAYE 237


                  .
gi 507089251  287 T 287
Cdd:TIGR00163 238 E 238
Psd COG0688
Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine ...
 14-285 4.46e-115

Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine decarboxylase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440452 [Multi-domain]  Cd Length: 243  Bit Score: 332.59  E-value: 4.46e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  14 PKLWLTRLAGWGASKRAGWLTkLVIDLFVKYYKVDMQEAQkpdTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVI 93
Cdd:COG0688    1 PKHLLSRLMGPIAREGWPFIA-LLIRTFIKRYGIDLSEAL---PSSYTSFNDFFFRDLKPGARPIPDDPDAVVSPADGKV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  94 SQLGKIEEDKILQAKGHNYSLEALLaGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQ 173
Cdd:COG0688   77 SQIGEIEEDRLLQAKGHPYSLEELL-GDSELAEKFEGGTFVSIFLSPFDYHRNHMPVDGTVVEVKYIPGKFLSVNPLALR 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 174 nvPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAgtitpprEGIIkrwtwpagendgsvaLLKGQEMGRFKLG 253
Cdd:COG0688  156 --PKLFARNERVVIVIETEFGPVAVVQVGALIVRRIVTYVK-------EGDT---------------LKKGEEMGLFKFG 211

                        250       260       270
                 ....*....|....*....|....*....|..
gi 507089251 254 STVINLFAPGKVNLveQLASLSVTKIGQPLAV 285
Cdd:COG0688  212 STVDLLLPKGAVEI--LVKPGQKVRAGETIGR 241
PS_Dcarbxylase pfam02666
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 63-264 4.18e-78

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


Pssm-ID: 396989 [Multi-domain]  Cd Length: 198  Bit Score: 236.79  E-value: 4.18e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   63 FNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNylMADLFRNGTFVTTYLSPRD 142
Cdd:pfam02666   1 LNAFFTRFLRDPARPIPAGPGAVVSPADGKISEIGEIEDDSVIQVKGVTYSLRELLGDD--KLDKFKGGTFIVIYLSPFD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  143 YHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVwagtitpPRE 222
Cdd:pfam02666  79 YHRNHAPVDGTVKEVRYIPGKLLPVNPAALKEIPNLFALNERVVLVIETTDGKVAVVQVGALNVGSIVLT-------VKP 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 507089251  223 GIIkrwtwpagendgsvaLLKGQEMGRFKLGSTVINLFAPGK 264
Cdd:pfam02666 152 GDE---------------VKKGEELGYFKFGSTVVLLFPKGK 178
 
Name Accession Description Interval E-value
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 1-289 0e+00

phosphatidylserine decarboxylase; Reviewed


Pssm-ID: 234591  Cd Length: 288  Bit Score: 582.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   1 MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMQEAQKPDTASYRTFNEFFVRPLRDEVRPIDT 80
Cdd:PRK00044   1 MLDRLKILLQYLLPKHLLTRLAGWLASSRAGWLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  81 DPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV 160
Cdd:PRK00044  81 DPNALVSPADGAISQLGPIEDGQIFQAKGHSYSLEALLGGDAALADPFRNGSFATIYLSPRDYHRVHMPCDGTLREMIYV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 161 PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPaGENDGSVA 240
Cdd:PRK00044 161 PGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIETVWAGTVTPPREGIIKRWDYP-EAGDGAIT 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 507089251 241 LLKGQEMGRFKLGSTVINLFAPGKVNLVEQLASLSVTKIGQPLAVSTEP 289
Cdd:PRK00044 240 LKKGAEMGRFKLGSTVINLFPPGKVQLAEQLQAGSVVRMGQPLAHITET 288
PS_decarb TIGR00163
phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as ...
 49-287 3.72e-140

phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 272936 [Multi-domain]  Cd Length: 238  Bit Score: 395.74  E-value: 3.72e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   49 MQEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLF 128
Cdd:TIGR00163   1 LDEAEKPDLADYRSLNEFFIRPLKLERRPVDKEPNALVSPADGVISEVGIINPNQILQVKGMDYSLEELLGEKNPLSPYF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  129 RNGT-FVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVG 207
Cdd:TIGR00163  81 RNGGfFVVTYLSPRDYHRFHSPCDCRLRKMRYFPGDLFSVNPLGLQNVPNLFVRNERVILVFDTEFGNMLMIPVGATNVG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  208 SIETVWAGTITP-PREGIIKRWTWPAgenDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLASLSVTKIGQPLAVS 286
Cdd:TIGR00163 161 SIRTNFDGNIQTnPRHEFTQTWTYNA---LGPVKLLKGEEMGYFELGSTVILLFEADAFQLSAHLAVGQEVKIGELLAYE 237


                  .
gi 507089251  287 T 287
Cdd:TIGR00163 238 E 238
Psd COG0688
Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine ...
 14-285 4.46e-115

Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine decarboxylase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440452 [Multi-domain]  Cd Length: 243  Bit Score: 332.59  E-value: 4.46e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  14 PKLWLTRLAGWGASKRAGWLTkLVIDLFVKYYKVDMQEAQkpdTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVI 93
Cdd:COG0688    1 PKHLLSRLMGPIAREGWPFIA-LLIRTFIKRYGIDLSEAL---PSSYTSFNDFFFRDLKPGARPIPDDPDAVVSPADGKV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  94 SQLGKIEEDKILQAKGHNYSLEALLaGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQ 173
Cdd:COG0688   77 SQIGEIEEDRLLQAKGHPYSLEELL-GDSELAEKFEGGTFVSIFLSPFDYHRNHMPVDGTVVEVKYIPGKFLSVNPLALR 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 174 nvPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAgtitpprEGIIkrwtwpagendgsvaLLKGQEMGRFKLG 253
Cdd:COG0688  156 --PKLFARNERVVIVIETEFGPVAVVQVGALIVRRIVTYVK-------EGDT---------------LKKGEEMGLFKFG 211

                        250       260       270
                 ....*....|....*....|....*....|..
gi 507089251 254 STVINLFAPGKVNLveQLASLSVTKIGQPLAV 285
Cdd:COG0688  212 STVDLLLPKGAVEI--LVKPGQKVRAGETIGR 241
PRK09629 PRK09629
bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional
 10-288 1.17e-97

bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional


Pssm-ID: 104071 [Multi-domain]  Cd Length: 610  Bit Score: 300.50  E-value: 1.17e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  10 QYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMQEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPA 89
Cdd:PRK09629 333 QYLLPHHLLSRLAGCVAECRVRWFKNAFTAWFARRYQVDMSQALVEDLTSYEHFNAFFTRALKADARPLDTTPGAILSPA 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  90 DGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNH 169
Cdd:PRK09629 413 DGAISQLGPIDHGRIFQAKGHSFSVLELLGGDPKLSAPFMGGEFATVYLSPKDYHRVHMPLAGTLREMVYVPGRIFSVNQ 492

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 170 LTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGiIKRWTWPAGENdGSVALLKGQEMGR 249
Cdd:PRK09629 493 TTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASVETVWAGLVTPPKRE-LKTFSYDEAAR-APIHLEKGAEMGR 570

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 507089251 250 FKLGSTVINLFAPGKVNLVEQLASLSVTKIGQPLAVSTE 288
Cdd:PRK09629 571 FKLGSTAIVLFGPNQVKWAEQLTAGSKVQMGQALAVPAQ 609
PS_Dcarbxylase pfam02666
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 63-264 4.18e-78

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


Pssm-ID: 396989 [Multi-domain]  Cd Length: 198  Bit Score: 236.79  E-value: 4.18e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   63 FNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNylMADLFRNGTFVTTYLSPRD 142
Cdd:pfam02666   1 LNAFFTRFLRDPARPIPAGPGAVVSPADGKISEIGEIEDDSVIQVKGVTYSLRELLGDD--KLDKFKGGTFIVIYLSPFD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  143 YHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVwagtitpPRE 222
Cdd:pfam02666  79 YHRNHAPVDGTVKEVRYIPGKLLPVNPAALKEIPNLFALNERVVLVIETTDGKVAVVQVGALNVGSIVLT-------VKP 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 507089251  223 GIIkrwtwpagendgsvaLLKGQEMGRFKLGSTVINLFAPGK 264
Cdd:pfam02666 152 GDE---------------VKKGEELGYFKFGSTVVLLFPKGK 178
PRK00723 PRK00723
phosphatidylserine decarboxylase; Provisional
 6-270 5.15e-61

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 179097 [Multi-domain]  Cd Length: 297  Bit Score: 196.68  E-value: 5.15e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   6 KLSLQYILPKLWLTRLAGWGASKRagwLTKLVIDLFVKYYKVDMQEAQKPdTASYRTFNEFFVRPLRDEVRPIDTDPNVL 85
Cdd:PRK00723  33 KNLLELLIKKKIFSKIYGWYCDSR---LSRKKIKPFVNDFNIDMSESEKP-LSDFKSFNDFFTRKLKPEARPIDQGENIL 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  86 VMPADGVISQLGKIEEDKILQAKGHNYSLEALLaGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLF 165
Cdd:PRK00723 109 ISPGDGRLLAYENIDLNSLFQVKGKTYSLKELL-GDPELAKKYAGGTCLILRLCPTDYHRFHFPDSGICEETRKIKGHYY 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 166 SVNHLTAQNVPNLFARNERVICLFDTE-FGPMAQILVGATIVGSIETvwagTITPpregiikrwtwpagenDGSVAllKG 244
Cdd:PRK00723 188 SVNPIALKKIFELFCENKREWSIFKSEnFGDILYVEVGATCVGSIIQ----TYKP----------------NKKVK--KG 245

                        250       260       270
                 ....*....|....*....|....*....|.
gi 507089251 245 QEMGRFKL-GSTVINLFAPGKV----NLVEQ 270
Cdd:PRK00723 246 DEKGYFKFgGSTVILFFEKNKIkidaDILEQ 276
PRK03934 PRK03934
phosphatidylserine decarboxylase; Provisional
 32-267 5.18e-55

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 235177 [Multi-domain]  Cd Length: 265  Bit Score: 180.14  E-value: 5.18e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  32 WLTKLVIDLFVKYYKVDMQEAQKPDtaSYRTFNEFFVRPLRDEvRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHN 111
Cdd:PRK03934  22 FIQKFINASYVKIFKIDMSEFKPPE--NYKSLNALFTRSLKKP-REFDEDPNIFISPCDSLITECGSLEEDKALQIKGME 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 112 YSLEALLAgnYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDT 191
Cdd:PRK03934  99 YSIEELLG--ESNSELVNGFDYINFYLSPKDYHRYHAPCDLEILEARYIPGKLYPVNLPSLEKNKNLFVKNERVVLKCKD 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 507089251 192 EFGP-MAQILVGATIVGSIETVWAGTI-TPPREGIIKRWTWpagENdgsVALLKGQEMGRFKLGSTVINLFAPGKVNL 267
Cdd:PRK03934 177 KKGKrLYFVFVGALNVGKMRFNFDERIqTNAKARFIQTYEY---EN---LKLKKGEELGNFEMGSTIVLFSQKGSLEF 248
PRK03140 PRK03140
phosphatidylserine decarboxylase; Provisional
 19-284 1.98e-53

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 179544 [Multi-domain]  Cd Length: 259  Bit Score: 175.56  E-value: 1.98e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  19 TRLAGWGASKragwLTKLVIDLFVKYYKVDMQEAQKPdTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGK 98
Cdd:PRK03140  20 YLLRKFAQSR----LSSILIPSYAKVYQINQDEMEKG-LKEYRTLHELFTRKLKEGKRPIDTDASSIVSPVDGVFADVGP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  99 IEEDKILQAKGHNYSLEALLaGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNL 178
Cdd:PRK03140  95 IEDDKTFDVKGKRYSIAEML-GNEERAQRYAGGTYMVLYLSPSHYHRIHSPISGTVTEQFVLGRKSYPVNALGLEYGKRP 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 179 FARNERVICLFDTEFGPMAQILVGATIVGSIEtvwagtitppregiikrWTwpaGENDgsvALLKGQEMGRFKLGSTVIN 258
Cdd:PRK03140 174 LSKNYRSVTEVNSDGEHMALVKVGAMFVNSIE-----------------LT---HERD---TVQKGEEMAYFSFGSTVVL 230

                        250       260
                 ....*....|....*....|....*.
gi 507089251 259 LFAPGKVNLVEQLASLSVTKIGQPLA 284
Cdd:PRK03140 231 LFEKDMIEPDQELKSGQEVRLGEKIG 256
PLN02938 PLN02938
phosphatidylserine decarboxylase
 5-263 1.53e-36

phosphatidylserine decarboxylase


Pssm-ID: 178526  Cd Length: 428  Bit Score: 135.72  E-value: 1.53e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251   5 FKLSLQYILPKLWLTRLagWGASKRAG---WLTKLVIDLFVKYYKVDMQEAQKPdTASYRTFNEFFVRPLRDEVRPIDTD 81
Cdd:PLN02938  86 TKASFLRLLPLRSISRL--WGSLTSVElpvWMRPYVYKAWARAFHSNLEEAALP-LEEYASLREFFVRSLKEGARPIDPD 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  82 PNVLVMPADGVISQLGKIEED--KILQAKGHNYSLEALLAGNYLM-----ADLFRNGTFVTT------------------ 136
Cdd:PLN02938 163 PNCLVSPVDGIVLRFGELKGPgtMIEQVKGFSYSVSALLGANSLLpmtaeGKEEKEEETLKDksskswlrvslaspklrd 242

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 137 ---------------YLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILV 201
Cdd:PLN02938 243 pvsaspmkglfycviYLGPGDYHRIHSPSDWNIEVRRHFSGRLFPVNERATRTIRNLYVENERVVLEGEWQEGFMAMAAV 322

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 507089251 202 GATIVGSIE--------TVWAGTITPPREGIIKRWTWPAGEndgSVALLKGQEMGRFKLGSTVINLF-APG 263
Cdd:PLN02938 323 GATNIGSIElfiepelrTNRPKKKIFNSEPPEERVYEPEGC---GLCLKKGDEVAVFNLGSTVVLVFeAPV 390
PLN02964 PLN02964
phosphatidylserine decarboxylase
 38-297 1.81e-35

phosphatidylserine decarboxylase


Pssm-ID: 215520 [Multi-domain]  Cd Length: 644  Bit Score: 135.37  E-value: 1.81e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  38 IDLFVKYYK--VDMQEAQKPdTASYRTFNEFFVRPLRDEVRPI---DTDpNVLVMPADGVISQLGKIEEDKILQAKGHNY 112
Cdd:PLN02964 390 IPKFLEFFKdqINMDEVKYP-LEHFKTFNEFFIRELKPGARPIacmDND-DVAVCAADCRLMAFQSVDDSTRFWIKGRKF 467

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 113 SLEALLaGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLtAQNVP--NLFARNERVICLFD 190
Cdd:PLN02964 468 SIKGLL-GKKVHSDAFLDGSLVIFRLAPQDYHRFHVPVSGVIEKFVDVPGSLYTVNPI-AVNSKycNVFTENKRAVCIIS 545

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 191 T-EFGPMAQILVGATIVGSIetvwagtitppregiikrwTWPAGENDgsvALLKGQEMGRFKLG-STVINLFAPGKVNLV 268
Cdd:PLN02964 546 TaEFGKVAFVAIGATMVGSI-------------------TFVKKEGD---HVKKGDELGYFSFGgSTVICVFEKDAIDID 603

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 507089251 269 EQLASLS------VTKIGQPLAVSTEPFVTPEAEP 297
Cdd:PLN02964 604 EDLLANSersletLVSVGMTLGVSTRTFARQVLEK 638
PTZ00403 PTZ00403
phosphatidylserine decarboxylase; Provisional
 36-260 4.23e-25

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 173594  Cd Length: 353  Bit Score: 103.39  E-value: 4.23e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  36 LVIDLFVKYYKVDMQEAQKPdTASYRTFNEFFVRPLRDEVRPI-DTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSL 114
Cdd:PTZ00403  84 PIYNFLIKYMGINKEEIKYP-IESYKSIGDFFSRYIREETRPIgDVSDYSIVSPCDSELTDYGELSSEYLENVKGVKFNV 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251 115 EALLAGNylMADLFRNGT----FVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFD 190
Cdd:PTZ00403 163 NTFLGSD--MQKKYNDGStkffYAIFYLSPKKYHHFHAPFNFKYKIRRHISGELFPVFQGMFKIINNLFNINERVILSGE 240

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 507089251 191 TEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGEN---DGSVALLKGQEMGRFKLGSTVINLF 260
Cdd:PTZ00403 241 WKGGNVYYAAISAYNVGNIKIINDEELVTNNLRTQLSYMGGDINTkiyDSYKSVEVGDEVGEFRMGSSIVVIF 313
PRK05305 PRK05305
phosphatidylserine decarboxylase family protein;
66-201 2.17e-05

phosphatidylserine decarboxylase family protein;


Pssm-ID: 235400 [Multi-domain]  Cd Length: 206  Bit Score: 44.79  E-value: 2.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507089251  66 FFvrplRDEVRPIDTDPNVLVMPADGVISQLGKIEEDkilqakghnysleallagnYLMADLFRNGTFvttyLSPRDYHR 145
Cdd:PRK05305  41 FF----RDPERVIPTDDGLVVSPADGKVVVIEEVVPP-------------------YGDEPRLRISIF----MSVFNVHV 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 507089251 146 VHMPCNGILREMIYVPGDLFSVNHLTAQnvpnlfARNERVICLFDTEFGpmAQILV 201
Cdd:PRK05305  94 NRAPVSGTVTKVEYRPGKFLNAFLDKAS------EENERNAVVIETADG--GEIGV 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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