NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|507082075|ref|WP_016152825|]
View 

MULTISPECIES: DeoR/GlpR family DNA-binding transcription regulator [Citrobacter]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-252 6.34e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 271.24  E-value: 6.34e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTTAlSDNIHFYKRAKSFFEEK 80
Cdd:COG1349    1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSA-AAEPPFAERETLNAEEK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  81 QIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQ-SEINVVSTGGELNKNTLSLQGRITKE 159
Cdd:COG1349   80 RAIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAErPNIEVILLGGELRPSSGSLVGPLAEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 160 IISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAEW 239
Cdd:COG1349  160 ALRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPEL 239

                        250
                 ....*....|...
gi 507082075 240 IAFCKENNIQLVY 252
Cdd:COG1349  240 LEALEEAGVEVIV 252
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-252 6.34e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 271.24  E-value: 6.34e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTTAlSDNIHFYKRAKSFFEEK 80
Cdd:COG1349    1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSA-AAEPPFAERETLNAEEK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  81 QIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQ-SEINVVSTGGELNKNTLSLQGRITKE 159
Cdd:COG1349   80 RAIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAErPNIEVILLGGELRPSSGSLVGPLAEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 160 IISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAEW 239
Cdd:COG1349  160 ALRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPEL 239

                        250
                 ....*....|...
gi 507082075 240 IAFCKENNIQLVY 252
Cdd:COG1349  240 LEALEEAGVEVIV 252
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 78-233 5.24e-54

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 171.54  E-value: 5.24e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   78 EEKQIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLSLQGRI 156
Cdd:pfam00455   4 EEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPdIEVILLGGEVRPKTGAFVGPL 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 507082075  157 TKEIISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNK 233
Cdd:pfam00455  84 AEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
PRK10411 PRK10411
L-fucose operon activator;
6-237 8.63e-36

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 127.23  E-value: 8.63e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   6 RIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGA-VLNTTALSDNIHFYKRAKSFFEEKQIIA 84
Cdd:PRK10411   5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAkYIHRQNQDSGDPFHIRLKSHYAHKADIA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  85 RNALPFIKNKTTMAADASSTAMELLKLLKERnDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLSLQGRITKEIISR 163
Cdd:PRK10411  85 REALAWIEEGMVIALDASSTCWYLARQLPDI-NIQVFTNSHPICQELGKRErIQLISSGGTLERKYGCYVNPSLISQLKS 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 507082075 164 YHVDILVMSCKGLDmQSGAL-DSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGA 237
Cdd:PRK10411 164 LEIDLFIFSCEGID-SSGALwDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVA 237
AgaR NF040755
transcriptional repressor AgaR;
1-240 1.35e-35

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 127.00  E-value: 1.35e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTtalsdniHFYKRAKSFFEE- 79
Cdd:NF040755   2 KGTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALIND-------GFIPGAEPSVEDk 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  80 -------KQIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLS 151
Cdd:NF040755  75 srlntavKRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEgVEVLMTGGHLRRQSLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 152 LQGRITKEIISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLIT 231
Cdd:NF040755 155 FYGDQAEQSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLIT 234


                 ....*....
gi 507082075 232 NKAPGAEWI 240
Cdd:NF040755 235 DSGIPEEYL 243
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-58 1.03e-17

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 74.57  E-value: 1.03e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 507082075     6 RIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVL 58
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-252 6.34e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 271.24  E-value: 6.34e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTTAlSDNIHFYKRAKSFFEEK 80
Cdd:COG1349    1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSA-AAEPPFAERETLNAEEK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  81 QIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQ-SEINVVSTGGELNKNTLSLQGRITKE 159
Cdd:COG1349   80 RAIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAErPNIEVILLGGELRPSSGSLVGPLAEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 160 IISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAEW 239
Cdd:COG1349  160 ALRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPEL 239

                        250
                 ....*....|...
gi 507082075 240 IAFCKENNIQLVY 252
Cdd:COG1349  240 LEALEEAGVEVIV 252
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 78-233 5.24e-54

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 171.54  E-value: 5.24e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   78 EEKQIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLSLQGRI 156
Cdd:pfam00455   4 EEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPdIEVILLGGEVRPKTGAFVGPL 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 507082075  157 TKEIISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNK 233
Cdd:pfam00455  84 AEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
PRK10411 PRK10411
L-fucose operon activator;
6-237 8.63e-36

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 127.23  E-value: 8.63e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   6 RIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGA-VLNTTALSDNIHFYKRAKSFFEEKQIIA 84
Cdd:PRK10411   5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAkYIHRQNQDSGDPFHIRLKSHYAHKADIA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  85 RNALPFIKNKTTMAADASSTAMELLKLLKERnDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLSLQGRITKEIISR 163
Cdd:PRK10411  85 REALAWIEEGMVIALDASSTCWYLARQLPDI-NIQVFTNSHPICQELGKRErIQLISSGGTLERKYGCYVNPSLISQLKS 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 507082075 164 YHVDILVMSCKGLDmQSGAL-DSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGA 237
Cdd:PRK10411 164 LEIDLFIFSCEGID-SSGALwDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVA 237
AgaR NF040755
transcriptional repressor AgaR;
1-240 1.35e-35

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 127.00  E-value: 1.35e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTtalsdniHFYKRAKSFFEE- 79
Cdd:NF040755   2 KGTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALIND-------GFIPGAEPSVEDk 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  80 -------KQIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLS 151
Cdd:NF040755  75 srlntavKRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEgVEVLMTGGHLRRQSLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 152 LQGRITKEIISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLIT 231
Cdd:NF040755 155 FYGDQAEQSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLIT 234


                 ....*....
gi 507082075 232 NKAPGAEWI 240
Cdd:NF040755 235 DSGIPEEYL 243
srlR PRK10434
DNA-binding transcriptional repressor;
1-251 3.20e-35

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 126.34  E-value: 3.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTTALSDNIHFYKRAKSffEEK 80
Cdd:PRK10434   1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINT--HKK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  81 QIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQ--SEINVVSTGGELNKNTLSLQGRITK 158
Cdd:PRK10434  79 ELIAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSEldNEQTILMPGGTFRKKSASFHGQLAE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 159 EIISRYHVDILVMSCKGLDMQSGALDSNEAEAeIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAE 238
Cdd:PRK10434 159 NAFEHFTFDKLFIGTDGIDLNAGVTTFNEVYT-VSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPA 237

                        250
                 ....*....|...
gi 507082075 239 WIAFCKENNIQLV 251
Cdd:PRK10434 238 FRQALEEKGIEVI 250
PRK09802 PRK09802
DeoR family transcriptional regulator;
5-251 9.28e-35

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 125.35  E-value: 9.28e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   5 DRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVL---NTTALSDNIHfykrAKSFFEE-- 79
Cdd:PRK09802  17 ERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALIcdsTTPSVEPSVE----DKSALNTam 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  80 KQIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQSE-INVVSTGGELNKNTLSLQGRITK 158
Cdd:PRK09802  93 KRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEgVELLMTGGHLRRQSQSFYGDQAE 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 159 EIISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAE 238
Cdd:PRK09802 173 QSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPAD 252

                        250
                 ....*....|...
gi 507082075 239 WIAFCKENNIQLV 251
Cdd:PRK09802 253 SLEGLRKAGVEVI 265
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
1-250 5.71e-30

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 112.26  E-value: 5.71e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTTalSDNIHFYKRAKSFFEEK 80
Cdd:PRK10906   1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAALPSS--SVNTPWHDRKATQTEEK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  81 QIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAE-AFHELAQSEINVVSTGGELNKNTLSLQGRITKE 159
Cdd:PRK10906  79 ERIARKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNvANTLMAKEDFRIILAGGELRSRDGGIIGEATLD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 160 IISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAEW 239
Cdd:PRK10906 159 FISQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQLPPASV 238

                        250
                 ....*....|.
gi 507082075 240 IAFCKENNIQL 250
Cdd:PRK10906 239 MQVIEDHHVQL 249
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-58 1.03e-17

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 74.57  E-value: 1.03e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 507082075     6 RIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVL 58
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 5-252 6.75e-14

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 68.96  E-value: 6.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   5 DRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLtrtYGGAVL------NTTALSDnihfyKRAKsFFE 78
Cdd:PRK10681   7 ERIGQLLQALKRSDKLHLKDAAALLGVSEMTIRRDLNAHSAPVVL---LGGYIVleprsaSHYLLSD-----QKSR-LVE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  79 EKQIIARNALPFIKNKTTMAADASSTAMELLKLLKERNDLTLLTNSAEAFHELAQS-EINVVSTGGELNKNT-----LSL 152
Cdd:PRK10681  78 EKRRAAQLAATLVEPNQTLFFDCGTTTPWIIEAIDNELPFTAVCYSLNTFLALQEKpHCRAILCGGEFHASNaifkpLDF 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 153 QgritkEIISRYHVDILVMSCKGLDMQSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITN 232
Cdd:PRK10681 158 Q-----QTLDNICPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMAMAQKHVLVVDHSKFGKVRPARMGDLTRFDTVVSD 232

                        250       260
                 ....*....|....*....|
gi 507082075 233 KAPGAEWIAFCKENNIQLVY 252
Cdd:PRK10681 233 RCPDDEFVKYAQAQRIKLMY 252
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
6-61 1.29e-12

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 61.12  E-value: 1.29e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 507082075    6 RIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTT 61
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNSS 56
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
1-251 2.50e-12

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 64.64  E-value: 2.50e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGGA-VLNTTALSD---NIHFYKRaksf 76
Cdd:PRK13509   1 MTEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAeAITQQRPRWtpmNIHQAQN---- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075  77 FEEKQIIARNALPFIKNKTTMAADASSTAMELLKLLKERnDLTLLTNsaeaFHELAQSEIN-----VVSTGGELNKN--- 148
Cdd:PRK13509  77 HDEKVRIAKAASQLCNPGESVVINCGSTAFLLGRELCGK-PVQIITN----YLPLANYLIDqehdsVIIMGGQYNKSqsi 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507082075 149 TLSLQGritkEIISRYHVDILVMSCKGL--------DMQSgaldsneAEAEIKktMIRQATEVALLVDHSKFDRKAFVQL 220
Cdd:PRK13509 152 TLSPQG----SENSLYAGHWMFTSGKGLtadglyktDMLT-------AMAEQK--MLSVVGKLVVLVDSSKIGERAGMLF 218

                        250       260       270
                 ....*....|....*....|....*....|...
gi 507082075 221 VDFSHINYLITNKAPGAEWIAFCKEN--NIQLV 251
Cdd:PRK13509 219 SRADQIDMLITGKNADPEVLQQLEAQgvSILLV 251
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 1-48 1.15e-03

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 39.68  E-value: 1.15e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 507082075   1 MAAKDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGF 48
Cdd:COG2378    1 MSRLERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELGV 48
COG3177 COG3177
Fic family protein [Transcription];
4-55 4.09e-03

Fic family protein [Transcription];


Pssm-ID: 442410 [Multi-domain]  Cd Length: 316  Bit Score: 37.74  E-value: 4.09e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 507082075   4 KDRIQAIKQMVVNDKKVAVSNLSSIFQVTEETIRRDLEKLEDEGFLTRTYGG 55
Cdd:COG3177  260 NERQRKLLELLFENPVLTASELAELLGVSRRTARRDLKDLVELGILEKVGGG 311
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH