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Conserved domains on  [gi|506351053|ref|WP_015870772|]
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4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE [Edwardsiella ictaluri]

Protein Classification

DMT family transporter( domain architecture ID 581036)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others

Gene Ontology:  GO:0055085|GO:0005215|GO:0005886
PubMed:  11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
EamA super family cl23754
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
14-108 7.87e-20

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


The actual alignment was detected with superfamily member PRK15051:

Pssm-ID: 474045  Cd Length: 111  Bit Score: 77.54  E-value: 7.87e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506351053  14 CAGQLCQKQAMCGVPRGSPRRHLLRWLMLALICLGLALLLWLVVLSRVAVSVAYPMLSLNYVLVLLAARFIWHERLNWRH 93
Cdd:PRK15051  14 VAGQLCQKQATRPVAIGKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRH 93
                         90
                 ....*....|....*
gi 506351053  94 IVGITLIMLGIILLG 108
Cdd:PRK15051  94 WCGVAFIIGGIVILG 108
 
Name Accession Description Interval E-value
PRK15051 PRK15051
4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional
14-108 7.87e-20

4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional


Pssm-ID: 185011  Cd Length: 111  Bit Score: 77.54  E-value: 7.87e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506351053  14 CAGQLCQKQAMCGVPRGSPRRHLLRWLMLALICLGLALLLWLVVLSRVAVSVAYPMLSLNYVLVLLAARFIWHERLNWRH 93
Cdd:PRK15051  14 VAGQLCQKQATRPVAIGKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRH 93
                         90
                 ....*....|....*
gi 506351053  94 IVGITLIMLGIILLG 108
Cdd:PRK15051  94 WCGVAFIIGGIVILG 108
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
63-107 1.32e-04

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 38.63  E-value: 1.32e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 506351053  63 VSVAYPMLSLNYVLVLLAARFIWHERLNWRHIVGITLIMLGIILL 107
Cdd:COG2510   91 ASIVAPIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVILL 135
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
59-107 8.14e-04

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 36.40  E-value: 8.14e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 506351053   59 SRVAVSVAYPMLSLNYVLVLLAARFIWHERLNWRHIVGITLIMLGIILL 107
Cdd:pfam00892  86 KYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLI 134
 
Name Accession Description Interval E-value
PRK15051 PRK15051
4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional
14-108 7.87e-20

4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional


Pssm-ID: 185011  Cd Length: 111  Bit Score: 77.54  E-value: 7.87e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506351053  14 CAGQLCQKQAMCGVPRGSPRRHLLRWLMLALICLGLALLLWLVVLSRVAVSVAYPMLSLNYVLVLLAARFIWHERLNWRH 93
Cdd:PRK15051  14 VAGQLCQKQATRPVAIGKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRH 93
                         90
                 ....*....|....*
gi 506351053  94 IVGITLIMLGIILLG 108
Cdd:PRK15051  94 WCGVAFIIGGIVILG 108
PRK02971 PRK02971
4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional
62-106 1.17e-05

4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional


Pssm-ID: 235094  Cd Length: 129  Bit Score: 41.13  E-value: 1.17e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 506351053  62 AVSVAYPMLSLNYVLVLLAARFI--WHERLNWRHIVGITLIMLGIIL 106
Cdd:PRK02971  73 PLSRAYPLLSLSYALVYLAAMLLpwFNETFSLKKTLGVACIMLGVWL 119
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
63-107 1.32e-04

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 38.63  E-value: 1.32e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 506351053  63 VSVAYPMLSLNYVLVLLAARFIWHERLNWRHIVGITLIMLGIILL 107
Cdd:COG2510   91 ASIVAPIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVILL 135
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
59-107 8.14e-04

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 36.40  E-value: 8.14e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 506351053   59 SRVAVSVAYPMLSLNYVLVLLAARFIWHERLNWRHIVGITLIMLGIILL 107
Cdd:pfam00892  86 KYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLI 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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