|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10600 |
PRK10600 |
nitrate/nitrite two-component system sensor histidine kinase NarX; |
30-602 |
0e+00 |
|
nitrate/nitrite two-component system sensor histidine kinase NarX;
Pssm-ID: 182581 [Multi-domain] Cd Length: 569 Bit Score: 1018.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 30 MSVSSWMSQSIQGNAHAINKAGSLRMQSYRLLSMVPLSAENEIYLQELEEDEISSDLQQAVRREGLSEQFTALRVFWLEN 109
Cdd:PRK10600 1 MAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLLKEMEQTAFSPELQRAAERDGQLAQLQALQDYWRNE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 110 LQPHLRQATHSSDASADVARFVKQLDDLVSAIDHKTEQRLMMVTLVQRIFIGIMLILLITTFFYLRRRLLTPWRRLVSMA 189
Cdd:PRK10600 81 LKPALQQAQNPEDVAADVAQFVAGLDALVSAFDHTTEMRIETVVLVHRVFAVFMALLLVFTIIWLRRRLLQPWRQLLSMA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 190 QAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDELSAMYHSLEQRVAEKTADLQQKNNLLSFLYRASRRLHTGAPLCSRLM 269
Cdd:PRK10600 161 NAVSHRDFTQRANISGRDEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEQKNQILSFLWQANRRLHSRAPLCERLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 270 PILNELSSLTPLRNIQLRLYEDNNQEQFHQFSEFSQSqpdHCPDNSCQSCGMQVKREEMQGEPHCWDLHDKHGQYGVVLA 349
Cdd:PRK10600 241 PVLNGLQNLTLLRDIELRVYETDDEENHQEFTCQSDM---TCDDKGCQLCPRGVLPVGDRGTTLKWRLSDKHGQYGILLA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 350 TLPGNTALSRDQNQLLNTLLEQLTSTLALERQSNHQQQLMLMEERATIARELHDSIAQSLSCLKIQVSCLQMQGGDLPPA 429
Cdd:PRK10600 318 TLPQGRHLSHDQQQLVDTLVEQLTATLALERQQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPES 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 430 SQQLLTEMREELNTAYRQLRELLTTFRLKLSESGLLAALRASVDEFSKRLGYPIELHYRLPPQSVSAHQGIHVLQIVREA 509
Cdd:PRK10600 398 SRELLSQIRNELNASWRQLRELLTTFRLQLTEPGLRPALEASCEEFSARFGFPVKLDYQLPPRLVPSHQAIHLLQIAREA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 510 LSNIYKHAQATQVDITLQLRQGHIELSVADNGIGIPDDASRANHYGLIIMRDRARGLHGECIVRRRPSGGTEVNVSFLAE 589
Cdd:PRK10600 478 LSNALKHAQASEVVVTVAQNQNQVKLSVQDNGCGVPENAERSNHYGLIIMRDRAQSLRGDCRVRRRESGGTEVVVTFIPE 557
|
570
....*....|...
gi 506320711 590 yRHRLPLTGETHD 602
Cdd:PRK10600 558 -KTFTDVQGDTHE 569
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
42-586 |
1.82e-123 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 375.73 E-value: 1.82e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 42 GNAHAINKAGSLRMQSYRLlsMVPLSAENEIYLQELEEDEIS------SDLQQAVRREGLSEQFTALRVFWLEnLQPHLR 115
Cdd:PRK10935 38 RDAEAINIAGSLRMQSYRL--AYDLQSGSPQLNAHLREFEQSlhspalKNLNRWYVPEDVKDRYALLIARWLE-MKSYLE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 116 QAtHSSDASADVARFVKQLDDLVSAIDHKTEQRLMMVTLVQRIFIGIMLILLITTFFYLRRRLLTPWRRLVSMAQAIGHG 195
Cdd:PRK10935 115 QG-DSRWYQANIANYVDQIDLFVLALQHFAERKLILLAAISLLGLILILTLVFFTVRFTRRQVVAPLNQLVTASQQIEKG 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 196 DF-TQRVTINGHDEMSTLGQVLNSMSDELSAMYHSLEQRVAEKTADLQQKNNLLSFLYRASRRLHTGAPLCSRLMPILNE 274
Cdd:PRK10935 194 QFdHIPLDTTLPNELGLLAKAFNQMSSELHKLYRSLEASVEEKTRKLTQANRSLEVLYQCSQALNASQIDVHCFRHILQI 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 275 LSSLTPLRNIQLRLYEDNNQEqfhqfseFSQSQPdhCPDNSCQSCGMQVKREEMqGEPHCwdlhdkhgQYGVVLATLPgn 354
Cdd:PRK10935 274 VRDHEGLDYLELEVGENEHWR-------ISEGQP--NPELPWQILPLTMEDTVL-GYLHW--------QASLPCPDEP-- 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 355 talsrdqnqLLNTLLEQLTSTLALERQSNHQQQLMLMEERATIARELHDSIAQSLSCLKIQVSCLQMQGGDLPPASQQLL 434
Cdd:PRK10935 334 ---------LMNNVAQMLGRGLYFNQAQKQQQQLLLMEERATIARELHDSLAQVLSYLKIQLTLLKRSLDEDNAKAQSII 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 435 TEMREELNTAYRQLRELLTTFRLKLSESGLLAALRASVDEFSKRLGYPIELHYRLPPQSVSAHQGIHVLQIVREALSNIY 514
Cdd:PRK10935 405 AEFDQALSDAYRQLRELLTTFRLTIQEANLGSALEEMLDQLRNQTDAKITLDCRLPSQALDAQQQVHLLQIIREATLNAI 484
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506320711 515 KHAQATQVDITLQLR-QGHIELSVADNGIGIPDDASRANHYGLIIMRDRARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:PRK10935 485 KHANASEIAVSCVTNpDGEHTVSIRDDGIGIGELKEPEGHYGLNIMQERAERLGGTLTISQPPGGGTTVSLTF 557
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
364-599 |
5.40e-55 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 187.13 E-value: 5.40e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 364 LLNTLLEQLTSTLALERQSNHQQQLMLMEERATIARELHDSIAQSLSCLKIQVSCLQMQGGDLPPASQQLLTEMREELNT 443
Cdd:COG4585 24 LVLLRARRAERAAELERELAARAEEAREEERRRIARELHDGVGQSLSAIKLQLEAARRLLDADPEAAREELEEIRELARE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 444 AYRQLRELLTTFR-LKLSESGLLAALRASVDEFSKRLGYPIELHYRLPPQSVSAHQGIHVLQIVREALSNIYKHAQATQV 522
Cdd:COG4585 104 ALAELRRLVRGLRpPALDDLGLAAALEELAERLLRAAGIRVELDVDGDPDRLPPEVELALYRIVQEALTNALKHAGATRV 183
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 506320711 523 DITLQLRQGHIELSVADNGIGIPDDASRANHYGLIIMRDRARGLHGECIVRRRPSGGTEVNVsflaeyrhRLPLTGE 599
Cdd:COG4585 184 TVTLEVDDGELTLTVRDDGVGFDPEAAPGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRA--------TLPLAAA 252
|
|
| NarX_sensor |
cd22900 |
ligand binding sensor domain of NarX, and related chemoreceptors; The periplasmic ligand ... |
38-153 |
5.17e-51 |
|
ligand binding sensor domain of NarX, and related chemoreceptors; The periplasmic ligand binding sensor domain of NarX is a histidine kinase receptor that responds to nitrate and nitrite to effect regulation of anaerobic respiration in various bacteria and similar proteins. It forms a homodimer and binds to ligands such as nitrate via the dimerization interface, a feature that appears to be conserved in this domain superfamily. NarX-NarL sensor-response regulator pair controls Escherichia coli gene expression in response to nitrate and nitrite. NarX has been shown to exhibit a clear kinetic preference for NarL over NarP, the sensor response partner of NarQ.
Pssm-ID: 438632 [Multi-domain] Cd Length: 116 Bit Score: 171.21 E-value: 5.17e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 38 QSIQGNAHAINKAGSLRMQSYRLLSMVPLSAENEIYLQELEEDEISSDLQQAVRREGLSEQFTALRVFWLENLQPHLRQA 117
Cdd:cd22900 1 NSIQGNAHAINKAGSLRMQSYRLLAAVPLNPQDQALLDELEQTLSSPELQRAARREGLQSQLQALQQYWQQQLKPALLAA 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 506320711 118 THSSDASADVARFVKQLDDLVSAIDHKTEQRLMMVT 153
Cdd:cd22900 81 KNPEDARAEVAAFVAQLDQLVSQIDQKTEQRLSLIS 116
|
|
| UhpB |
COG3851 |
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction ... |
369-578 |
1.27e-30 |
|
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction mechanisms];
Pssm-ID: 443060 [Multi-domain] Cd Length: 493 Bit Score: 125.50 E-value: 1.27e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 369 LEQLTSTLALERQSNHQ--QQLMLMEE--RATIARELHDSIAQSLSCLKIQVSCLQMQGGDlpPASQQLLTEMREELNTA 444
Cdd:COG3851 264 QRQLNQQLEQELRENRAlaRQLVSAEEseRREIARELHDEIGQNITAIRTQASILKRLAPQ--PEIEQSAQSIESLALRI 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 445 YRQLRELLTTFRLK-LSESGLLAALRASVDEFskRLGYP---IELHYRLPPQSVSAHQGIHVLQIVREALSNIYKHAQAT 520
Cdd:COG3851 342 YDTTRRLLDRLRPAvLDELGLEEALRELPREL--AFEEPgisCQLDLRGDPSLLDDTLQLTLYRLVQEALTNILKHAEAS 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 506320711 521 QVDITLQLRQGHIELSVADNGIGIPDDaSRANHYGLIIMRDRARGLHGECIVRRRPSG 578
Cdd:COG3851 420 QIRISLSQDKRLLSLEIRDDGIGLPPE-LRAKGFGLRGMRERVRALGGDFRLSSAPKG 476
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
502-586 |
1.95e-26 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 103.02 E-value: 1.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 502 VLQIVREALSNIYKHAQATQVDITLQLRQGHIELSVADNGIGIPDDA-SRANHYGLIIMRDRARGLHGECIVRRRPSGGT 580
Cdd:cd16917 1 LYRIVQEALTNALKHAGASRVRVTLSYTADELTLTVVDDGVGFDGPApPGGGGFGLLGMRERAELLGGTLTIGSRPGGGT 80
|
....*.
gi 506320711 581 EVNVSF 586
Cdd:cd16917 81 RVTARL 86
|
|
| NarX_NarQ_sensor |
cd19408 |
ligand binding sensor domain of NarX and NarQ, and related chemoreceptors; The periplasmic ... |
38-149 |
5.25e-22 |
|
ligand binding sensor domain of NarX and NarQ, and related chemoreceptors; The periplasmic ligand binding sensor domain of NarX and NarQ is a histidine kinase receptor that responds to nitrate and nitrite to effect regulation of anaerobic respiration in various bacteria and similar proteins. It forms a homodimer and binds to ligands such as nitrate via the dimerization interface, a feature that appears to be conserved in this domain superfamily. NarX-NarL sensor-response regulator pair, along with NarQ-NarP, control Escherichia coli gene expression in response to nitrate and nitrite. NarX has been shown to exhibit a clear kinetic preference for NarL over NarP, whereas NarQ exhibits a relatively slight kinetic preference for NarL. There is asymmetry in the Nar cross-regulation network with NarQ shown to interact similarly with both response regulators, while NarX interacts preferentially with NarL.
Pssm-ID: 438626 [Multi-domain] Cd Length: 126 Bit Score: 91.92 E-value: 5.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 38 QSIQGNAHAINKAGSLRMQSYRLLSMVPLSAENEI-----YLQELEEDEISSDLQQAVRREG---LSEQFTALRVFWLEN 109
Cdd:cd19408 1 ESTEGDAAAINLAGSLRMQSYRLASLLLQAALEPAeqlaqLIDEFEQRLNSPALTRALPRDSdhpLRQAYQAVLQHWQQE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 506320711 110 LQP----HLRQATHSSDASADVARFVKQLDDLVSAIDHKTEQRL 149
Cdd:cd19408 81 LRPaleaAASGAADREAYLAEVDEFVAQIDQLVKLLQQDTEAKI 124
|
|
| PRK11644 |
PRK11644 |
signal transduction histidine-protein kinase/phosphatase UhpB; |
341-585 |
9.16e-21 |
|
signal transduction histidine-protein kinase/phosphatase UhpB;
Pssm-ID: 236945 [Multi-domain] Cd Length: 495 Bit Score: 95.81 E-value: 9.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 341 HGQYGVVLATLPGNTAL--SRDQNQ----LLNTLLEQ-LTSTL---ALERQ------------SNHQ--QQLMLMEE--R 394
Cdd:PRK11644 223 YGWQGALLATLLNAIALiaSQTWHDhpvdLLLSLLAQsLTGLLlgaGIQRQrelnqslqkelaRNRHlaERLLETEEsvR 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 395 ATIARELHDSIAQSLSCLKIQVSCLQMqggdLPPASQQLLT--EMREELN-TAYRQLRELLTTFRLK-LSESGLLAALRA 470
Cdd:PRK11644 303 RDVARELHDEIGQTITAIRTQAGIIKR----LAADNASVKQsaQLIEQLSlGVYDTVRRLLGRLRPRqLDDLTLEQAIRS 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 471 SVDEFS-KRLGYPIELHYRLPPQSVSAHQGIHVLQIVREALSNIYKHAQATQVDITLQLRQGHIELSVADNGIGIPdDAS 549
Cdd:PRK11644 379 LMREMElEDRGIVSHLDWRIDESALSETQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLP-PGS 457
|
250 260 270
....*....|....*....|....*....|....*.
gi 506320711 550 RANHYGLIIMRDRARGLHGEciVRRRPSGGTEVNVS 585
Cdd:PRK11644 458 GQQGFGLRGMRERVTALGGT--LTISCTHGTRLSVS 491
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
147-586 |
1.09e-15 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 79.62 E-value: 1.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 147 QRLMMVTLVqrIFIGIMLILLITTFFYLRRRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDELSAM 226
Cdd:COG5000 4 QILFLLLLL--LIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 227 YHSLEQRVAEKTADLQQ---------KNNLLSFLYRASRRLhTGAPLCSRLMPILNELSSLTPLRNIQLRLYEDNNQEQF 297
Cdd:COG5000 82 REELEERRRYLETILENlpagvivldADGRITLANPAAERL-LGIPLEELIGKPLEELLPELDLAELLREALERGWQEEI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 298 hqfsefsqsqpdhcpdnscqscgmQVKREEMQgephcwdlhdkhgqygvvlaTLPGNTALSRDQNQLLntLLEQLTSTLA 377
Cdd:COG5000 161 ------------------------ELTRDGRR--------------------TLLVRASPLRDDGYVI--VFDDITELLR 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 378 LERQSNHQQqlmlmeeratIAREL-HDsIAQSLSCLKIQVSCLQMQGGDLPPASQQLLTEMreeLNTAYRQ---LRELLT 453
Cdd:COG5000 195 AERLAAWGE----------LARRIaHE-IKNPLTPIQLSAERLRRKLADKLEEDREDLERA---LDTIIRQvdrLKRIVD 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 454 TFR-------LKLSESGLLAALRASVDEFSKRLGYP-IELHYRLPPQSVS----AHQgihvlqiVREALSNIYKHA-QAT 520
Cdd:COG5000 261 EFLdfarlpePQLEPVDLNELLREVLALYEPALKEKdIRLELDLDPDLPEvladRDQ-------LEQVLINLLKNAiEAI 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 521 ----QVDITLQLRQGHIELSVADNGIGIPDDAsRAN----HY---------GLIIMRDRARGLHGECIVRRRPSGGTEVN 583
Cdd:COG5000 334 eeggEIEVSTRREDGRVRIEVSDNGPGIPEEV-LERifepFFttkpkgtglGLAIVKKIVEEHGGTIELESRPGGGTTFT 412
|
...
gi 506320711 584 VSF 586
Cdd:COG5000 413 IRL 415
|
|
| HisKA_3 |
pfam07730 |
Histidine kinase; This is the dimerization and phosphoacceptor domain of a sub-family of ... |
393-456 |
6.92e-15 |
|
Histidine kinase; This is the dimerization and phosphoacceptor domain of a sub-family of histidine kinases. It shares sequence similarity with pfam00512 and pfam07536.
Pssm-ID: 429624 [Multi-domain] Cd Length: 68 Bit Score: 69.57 E-value: 6.92e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 506320711 393 ERATIARELHDSIAQSLSCLKIQVSCLQMQGGDLPPASQQLLTEMREELNTAYRQLRELLTTFR 456
Cdd:pfam07730 1 ERNRIARELHDSVGQSLTAIKLQLELARRLLDRDPEEAREQLDAIRELAREALQELRRLLGDLR 64
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
500-586 |
4.08e-14 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 68.83 E-value: 4.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 500 IHVLQIVREALSNIYKHAQA-TQVDITLQLRQGHIELSVADNGIGIP--------------DDASRANH---YGLIIMRD 561
Cdd:smart00387 4 DRLRQVLSNLLDNAIKYTPEgGRITVTLERDGDHVEITVEDNGPGIPpedlekifepffrtDKRSRKIGgtgLGLSIVKK 83
|
90 100
....*....|....*....|....*
gi 506320711 562 RARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:smart00387 84 LVELHGGEISVESEPGGGTTFTITL 108
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
500-586 |
1.23e-13 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 67.39 E-value: 1.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 500 IHVLQIVREALSNIYKHA-QATQVDITLQlRQGHIELSVADNGIGIPDDA--------SRANH-------YGLIIMRDRA 563
Cdd:pfam02518 4 LRLRQVLSNLLDNALKHAaKAGEITVTLS-EGGELTLTVEDNGIGIPPEDlprifepfSTADKrggggtgLGLSIVRKLV 82
|
90 100
....*....|....*....|...
gi 506320711 564 RGLHGECIVRRRPSGGTEVNVSF 586
Cdd:pfam02518 83 ELLGGTITVESEPGGGTTVTLTL 105
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
504-586 |
5.11e-13 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 65.32 E-value: 5.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 504 QIVREALSNIYKHA-QATQVDITLQLRQGHIELSVADNGIGIP--------------DDASRANHY--GLIIMRDRARGL 566
Cdd:cd00075 3 QVLSNLLDNALKYSpPGGTIEISLRQEGDGVVLEVEDNGPGIPeedleriferfyrgDKSREGGGTglGLAIVRRIVEAH 82
|
90 100
....*....|....*....|
gi 506320711 567 HGECIVRRRPSGGTEVNVSF 586
Cdd:cd00075 83 GGRITVESEPGGGTTFTVTL 102
|
|
| NarQ_sensor |
cd22899 |
ligand binding sensor domain of NarQ, and related chemoreceptors; The periplasmic ligand ... |
41-151 |
5.83e-13 |
|
ligand binding sensor domain of NarQ, and related chemoreceptors; The periplasmic ligand binding sensor domain of NarQ is a histidine kinase receptor that responds to nitrate and nitrite to effect regulation of anaerobic respiration in various bacteria and similar proteins. It forms a homodimer and binds to ligands such as nitrate via the dimerization interface, a feature that appears to be conserved in this domain superfamily. NarQ-NarP sensor-response regulator pair controls Escherichia coli gene expression in response to nitrate and nitrite. NarQ has been shown to interact equally with NarP and NarL response regulators; NarL is the sensor response partner of NarX.
Pssm-ID: 438631 [Multi-domain] Cd Length: 116 Bit Score: 65.62 E-value: 5.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 41 QGNAHAINKAGSLRMQSYRLL-SMVPLSAENEIYLQELEE----DEISSDLQQAVRREgLSEQFTALRVFWLEnLQPHLR 115
Cdd:cd22899 4 LSDAEAINVAGSLRMQSYRLAyDLESESPLLEQHIAQYEQslhsPALQSLDRWYVPDE-VKQRYQQLLARWQE-MKQYLL 81
|
90 100 110
....*....|....*....|....*....|....*.
gi 506320711 116 QAtHSSDASADVARFVKQLDDLVSAIDHKTEQRLMM 151
Cdd:cd22899 82 QG-DPASYLQQVASYVDQIDQFVLALQHFAERKLRL 116
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
40-299 |
1.52e-12 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 69.91 E-value: 1.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 40 IQGNAHAINKAGSLRMQSYRLLSMVPLSAENEIYLQELEEDEISSDLQQAVRREGLSEQFTALRVFWLENLQPHLRQATH 119
Cdd:COG3850 4 LLLLALALLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 120 SSDASADVARFVKQLDDLVSAIDHKTEQRLMMVTLVQRIFIGIMLILLITTFFYLRRRLLTPWRRLVSMAQAIGHGDFTQ 199
Cdd:COG3850 84 LLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 200 RVTINGHDEMSTLGQVLNSMSDELSAMYHSLEQRVAEKTADLQQKNNLLSFLYRASRRLHTGAPLCSRLMPILNELSSLT 279
Cdd:COG3850 164 RVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLL 243
|
250 260
....*....|....*....|
gi 506320711 280 PLRNIQLRLYEDNNQEQFHQ 299
Cdd:COG3850 244 LQDALAESELLALNILAGLL 263
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
371-586 |
1.02e-11 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 65.31 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 371 QLTSTLALERQSNHQQQLMLmeerATIARELHdsiaQSLSCLKIQVSCLQMQGGDLPPASQQLLTEMREELNTAYRQLRE 450
Cdd:COG2205 1 ELEEALEELEELERLKSEFL----ANVSHELR----TPLTSILGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIED 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 451 LLT-------TFRLKLSESGLLAALRASVDEFSKRL-GYPIELHYRLPPQSVSAHQ-GIHVLQIVREALSNIYKHAQA-T 520
Cdd:COG2205 73 LLDlsrlesgKLSLELEPVDLAELLEEAVEELRPLAeEKGIRLELDLPPELPLVYAdPELLEQVLANLLDNAIKYSPPgG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 521 QVDITLQLRQGHIELSVADNGIGIPDD-----------ASRANHY-----GLIIMRDRARGLHGECIVRRRPSGGTEVNV 584
Cdd:COG2205 153 TITISARREGDGVRISVSDNGPGIPEEeleriferfyrGDNSRGEggtglGLAIVKRIVEAHGGTIWVESEPGGGTTFTV 232
|
..
gi 506320711 585 SF 586
Cdd:COG2205 233 TL 234
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
176-227 |
1.87e-11 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 59.18 E-value: 1.87e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 506320711 176 RRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDELSAMY 227
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETI 52
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
179-223 |
2.64e-11 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 58.61 E-value: 2.64e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 506320711 179 LTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDEL 223
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HAMP |
pfam00672 |
HAMP domain; |
174-225 |
2.90e-11 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 58.79 E-value: 2.90e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 506320711 174 LRRRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDELSA 225
Cdd:pfam00672 2 LARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
460-582 |
1.51e-10 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 59.16 E-value: 1.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 460 SESGLLAALRASVDEFSKRLGYPIELHYRlppqsvsahqgihVLQIVREALSNIYKHAQA----TQVDITLQLRQGHIEL 535
Cdd:COG2172 6 ADLEDLGLARRAVRALLRELGLDEDDADD-------------LVLAVSEAVTNAVRHAYGgdpdGPVEVELELDPDGLEI 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 506320711 536 SVADNGIGI-------PDDASRANHYGLIIMR---DrarglhgECIVRRRPsGGTEV 582
Cdd:COG2172 73 EVRDEGPGFdpedlpdPYSTLAEGGRGLFLIRrlmD-------EVEYESDP-GGTTV 121
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
379-586 |
2.02e-10 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 63.39 E-value: 2.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 379 ERQSNHQQQLMLMEERATIARELHD------SIAQSLsclkiqvscLQMQGGDLP-PASQQLLTEMREELNT---AYRQL 448
Cdd:COG3920 280 ERKRAEEELEASLEEKELLLRELHHrvknnlQVVSSL---------LRLQARRADdPEAREALEESQNRIQAlalVHELL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 449 RELLTTFRLKLSE--SGLLAALRASVDefskrlGYPIELHYRLPPQSVSAHQGIHVLQIVREALSNIYKHA----QATQV 522
Cdd:COG3920 351 YQSEDWEGVDLRDylRELLEPLRDSYG------GRGIRIELDGPDVELPADAAVPLGLILNELVTNALKHAflsgEGGRI 424
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 506320711 523 DITLQLRQGHIELSVADNGIGIPDDASRANH--YGLIIMRDRARGLHGEciVRRRPSGGTEVNVSF 586
Cdd:COG3920 425 RVSWRREDGRLRLTVSDNGVGLPEDVDPPARkgLGLRLIRALVRQLGGT--LELDRPEGTRVRITF 488
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
46-249 |
2.45e-10 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 63.12 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 46 AINKAGSLRMQSYRLLSMVPLSAENEIYLQELEEDEISSDLQQAVRREGLSEQFTALRVFWLENLQPHLRQATHSSDASA 125
Cdd:COG0840 75 LLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLA 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 126 DVARFVKQLDDLVSAIDHKTEQRLMMVTLVQRIFIGIMLILLITTFFyLRRRLLTPWRRLVSMAQAIGHGDFTQRVTING 205
Cdd:COG0840 155 AAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALL-LSRSITRPLRELLEVLERIAEGDLTVRIDVDS 233
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 506320711 206 HDEMSTLGQVLNSMSDELSAMYHSLEQ---RVAEKTADLQQKNNLLS 249
Cdd:COG0840 234 KDEIGQLADAFNRMIENLRELVGQVREsaeQVASASEELAASAEELA 280
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
419-586 |
1.32e-08 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 56.84 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 419 LQMQGGDLPPASQQLLTEMREELNTAYRQLRELLTTFRLklsESG----------LLAALRASVDEFSKRL-GYPIELHY 487
Cdd:COG0642 132 LELLLEELDEEQREYLETILRSADRLLRLINDLLDLSRL---EAGklelepepvdLAELLEEVVELFRPLAeEKGIELEL 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 488 RLPPQSVSAH-QGIHVLQIVREALSNIYKHAQA-TQVDITLQLRQGHIELSVADNGIGIPDD-----------ASRANHY 554
Cdd:COG0642 209 DLPDDLPTVRgDPDRLRQVLLNLLSNAIKYTPEgGTVTVSVRREGDRVRISVEDTGPGIPPEdlerifepffrTDPSRRG 288
|
170 180 190
....*....|....*....|....*....|....*..
gi 506320711 555 -----GLIIMRDRARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:COG0642 289 ggtglGLAIVKRIVELHGGTIEVESEPGKGTTFTVTL 325
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
419-586 |
2.92e-08 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 56.10 E-value: 2.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 419 LQMQGGDLPPASQQLLTEMREELNTAYRQLRELLT-------TFRLKLSESGLLAALRASVDEFSKRLG-YPIELHYRLP 490
Cdd:COG5002 190 LLDGAADDPEERREYLEIILEEAERLSRLVNDLLDlsrlesgELKLEKEPVDLAELLEEVVEELRPLAEeKGIELELDLP 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 491 PQSVSAH-QGIHVLQIVREALSNIYKHAQA-TQVDITLQLRQGHIELSVADNGIGIPD-------------DASRANHY- 554
Cdd:COG5002 270 EDPLLVLgDPDRLEQVLTNLLDNAIKYTPEgGTITVSLREEDDQVRISVRDTGIGIPEedlpriferfyrvDKSRSRETg 349
|
170 180 190
....*....|....*....|....*....|....*.
gi 506320711 555 ----GLIIMRDRARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:COG5002 350 gtglGLAIVKHIVEAHGGRIWVESEPGKGTTFTITL 385
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
1-260 |
4.39e-07 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 52.81 E-value: 4.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 1 MLKRFLLPLSLVNQVALLMLLLGLLGIAGMSVSSWMSQSIQGNAHAINKAGSLRMQSYRLLSMVPLSAENEIYLQELEED 80
Cdd:COG2770 59 LLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLAL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 81 EISSDLQQAVRREGLSEQFTALRVFWLENLQPHLRQATHSSDASADVARFVKQLDDLVSAIDHKTEQRLMMVTLVQRIFI 160
Cdd:COG2770 139 ALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 161 GIMLILLITTFFYLRRRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDELSAMYHSLEQRVAEKTAD 240
Cdd:COG2770 219 LLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAE 298
|
250 260
....*....|....*....|
gi 506320711 241 LQQKNNLLSFLYRASRRLHT 260
Cdd:COG2770 299 LARLLEALLELLLALLLLLL 318
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
505-580 |
8.06e-07 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 47.26 E-value: 8.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 505 IVREALSNIYKHAQA----TQVDITLQLRQGHIELSVADNGIGI-------PDDASRANHYGLIIMrdraRGLHGECIVR 573
Cdd:cd16936 4 AVSEAVTNAVRHAYRhdgpGPVRLELDLDPDRLRVEVTDSGPGFdplrpadPDAGLREGGRGLALI----RALMDEVGYR 79
|
....*..
gi 506320711 574 RRPSGGT 580
Cdd:cd16936 80 RTPGGKT 86
|
|
| PilJ |
pfam13675 |
Type IV pili methyl-accepting chemotaxis transducer N-term; This domain is found on many type ... |
35-125 |
9.55e-07 |
|
Type IV pili methyl-accepting chemotaxis transducer N-term; This domain is found on many type IV pili methyl-accepting chemotaxis transducer proteins where there is also a HAMP signature towards the C-terminus. It is a monomodular four-helix bundle and recognizes nitrate and nitrite (Matilla et al. FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 433397 [Multi-domain] Cd Length: 112 Bit Score: 47.86 E-value: 9.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 35 WMSQSIQGNAHAINKAGSLRMQSYRLLSMVPLSAENEIYLQELEED----------------EISSDLQQAVRREGLSEQ 98
Cdd:pfam13675 1 WTLWQSEGDAAAINAAGSLRMQSQRLAKSVLLALAGNYDLAEAFADleesidqfdrtlaalaLGDLARGLFVPAGAIRAQ 80
|
90 100
....*....|....*....|....*..
gi 506320711 99 FTALRVFWlENLQPHLRQATHSSDASA 125
Cdd:pfam13675 81 LEAVQPLW-ERLRKPAEAVLAQQDTLA 106
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
162-241 |
2.18e-06 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 50.80 E-value: 2.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 162 IMLILLITTFFYLRRRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDELSAMYHSLEQRVAEKTADL 241
Cdd:PRK15347 305 ILVLLTSVLFLLLRRYLAKPLWRFVDIINKTGPAALEPRLPENRLDELGSIAKAYNQLLDTLNEQYDTLENKVAERTQAL 384
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
468-586 |
2.86e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 47.03 E-value: 2.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 468 LRASVDEFSKRLGYPIELHYRLPPqsVSAHQGIHVLQIVREALSNIYKHAQATQVDITLQLR----QGHIELSVADNGIG 543
Cdd:cd16951 8 IASAINAIHAVGDIRINITGDTGP--VSSEVATAIGLVVNELLQNALKHAFSDREGGTITIRsvvdGDYLRITVIDDGVG 85
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 506320711 544 IPDDAS--RANHYGLIIMRDRARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:cd16951 86 LPQDEDwpNKGSLGLQIVRSLVEGELKAFLEVQSAENGTRVNIDI 130
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
102-243 |
4.59e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 46.16 E-value: 4.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 102 LRVFWLENLQPHLRQATHSSDASADVARFVKQLDDLVSAIDHKTEQRLMMVTLVQRIFIGIMLILLITTFF---YLRRRL 178
Cdd:COG2972 102 LLALILLLALLLLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLlsyLLSRSI 181
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 506320711 179 LTPWRRLVSMAQAIGHGDFTqRVTINGHDEMSTLGQVLNSMSDELSAMYHSL-EQRVAEKTADLQQ 243
Cdd:COG2972 182 TRPIKRLKKAMKKVEKGDLV-RLEVSGNDEIGILARSFNEMVERIKELIEEVyELELEKKEAELKA 246
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
125-248 |
4.88e-05 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 46.22 E-value: 4.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 125 ADVARFVKQLDDLVSAIDHKTEQRLMMVTLVqrIFI----GIMLILLITtFFYLRRRLLtpwRRLVSMAQA---IGHGDF 197
Cdd:COG4192 297 TQISGLVGNSREQLVALNQETAQLVQQSGIL--LLAiallSLLLAVLIN-YFYVRRRLV---KRLNALSDAmaaIAAGDL 370
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 506320711 198 TQRVTINGHDEMSTLGQVLNSMSDELSAMYHSLEQRVAEK---TADLQQKNNLL 248
Cdd:COG4192 371 DVPIPVDGNDEIGRIARLLRVFRDQAIEKTQELETEIEERkriEKNLRQTQDEL 424
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
163-223 |
9.94e-05 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 45.01 E-value: 9.94e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 506320711 163 MLILLITTFFyLRRRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDEL 223
Cdd:PRK10549 174 TLLAALATFL-LARGLLAPVKRLVEGTHKLAAGDFTTRVTPTSRDELGRLAQDFNQLASTL 233
|
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
465-586 |
1.01e-04 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 42.28 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 465 LAALRASVDEFSKRLGypielhyrLPPQSVsahqgIHVLQIVREALSNIYKHAQ----ATQVDITLQLRQGHIELSVADN 540
Cdd:pfam13581 8 LRAARRVLEAVLRRAG--------LPEELL-----DEVELAVGEACTNAVEHAYregpEGPVEVRLTSDGGGLVVTVADS 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 506320711 541 GIGIP-----------DDASRANH-YGLIIMrdraRGLHGECIVRRRPsGGTEVNVSF 586
Cdd:pfam13581 75 GPPFDpltlpppdleePDEDRKEGgRGLALI----RGLMDDVEYTRGG-EGNTVRMRK 127
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
505-586 |
1.57e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 44.66 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 505 IVREALSNIYKHA--QATQVDITLQLRQ---GHIELSVADNGIGIPD--DASRANHYGLIIMRDRARGLHGECIVRRRps 577
Cdd:PRK13560 715 IISELLSNALKHAfpDGAAGNIKVEIREqgdGMVNLCVADDGIGLPAgfDFRAAETLGLQLVCALVKQLDGEIALDSR-- 792
|
....*....
gi 506320711 578 GGTEVNVSF 586
Cdd:PRK13560 793 GGARFNIRF 801
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
483-586 |
1.81e-04 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 44.45 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 483 IELHYRLPPQSVSAHQGIhvlqiVREALSNIYKHA-----QATQVDITLQLRQGHIELSVADNGIGIPDDA--------- 548
Cdd:PRK11100 351 ITLRLRPDDARVLGDPFL-----LRQALGNLLDNAidfspEGGTITLSAEVDGEQVALSVEDQGPGIPDYAlpriferfy 425
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 506320711 549 --SRANH------YGLIIMRDRARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:PRK11100 426 slPRPANgrkstgLGLAFVREVARLHGGEVTLRNRPEGGVLATLTL 471
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
356-547 |
1.86e-04 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 44.02 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 356 ALSRDQNQLLNTLLEQLTSTLALERQSNHQQQLMLMEER--------ATIArelHDsIAQSLSCLK--IQVSCLQMQGGD 425
Cdd:COG4191 100 ALDAEENAELEELERDITELERAEEELRELQEQLVQSEKlaalgelaAGIA---HE-INNPLAAILgnAELLRRRLEDEP 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 426 LPPASQQLLTEMREELNTAYRQLRELLTTFR---LKLSESGLLAALRASVDEFSKRLGYP-IELHYRLPPQ--SVSAHQG 499
Cdd:COG4191 176 DPEELREALERILEGAERAAEIVRSLRAFSRrdeEEREPVDLNELIDEALELLRPRLKARgIEVELDLPPDlpPVLGDPG 255
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 506320711 500 iHVLQIV-------REALSNIYKHaqatQVDITLQLRQGHIELSVADNGIGIPDD 547
Cdd:COG4191 256 -QLEQVLlnllinaIDAMEEGEGG----RITISTRREGDYVVISVRDNGPGIPPE 305
|
|
| PRK15041 |
PRK15041 |
methyl-accepting chemotaxis protein; |
158-223 |
3.03e-04 |
|
methyl-accepting chemotaxis protein;
Pssm-ID: 185001 [Multi-domain] Cd Length: 554 Bit Score: 43.79 E-value: 3.03e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506320711 158 IFIGIMLILL---ITTFFYLRRRLLTPWRRLVSMAQAIGHGDFTQRVTINGHDEMSTLGQVLNSMSDEL 223
Cdd:PRK15041 195 ILVGVMIVVLaviFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGEL 263
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
510-586 |
3.83e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 40.69 E-value: 3.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 510 LSNIYKHAQAtQVDITLQLRQGHIELSVADNGIGIPDDA-------------SRANH-YGLIIMRDRARGLHGECIVRRR 575
Cdd:cd16954 46 LDNACKWCLE-FVEVTARQTDGGLHLIVDDDGPGVPESQrskifqrgqrldeQRPGQgLGLAIAKEIVEQYGGELSLSDS 124
|
90
....*....|.
gi 506320711 576 PSGGTEVNVSF 586
Cdd:cd16954 125 PLGGARFEVVF 135
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
521-586 |
1.21e-03 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 41.37 E-value: 1.21e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506320711 521 QVDITLQLRQGHIELSVADNGIGIPDDA------------SRANH-YGLIIMRDRARGLHGECIVRRRPSGGTEVNVSF 586
Cdd:COG3290 306 RVELSIRDDGDELVIEVEDSGPGIPEELlekifergfstkLGEGRgLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRL 384
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
430-596 |
1.75e-03 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 41.13 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 430 SQQLLTEMREELNTAYRQLR----ELLTTFRL-------KLSESGLLAALRASVDEFskRLGYP-IELHYRLPPQSVSAH 497
Cdd:PRK10604 237 SDNLSAAESQALNRDIGQLEalieELLTYARLdrpqnelHLSEPDLPAWLSTHLADI--QAVTPeKTVRLDTPHQGDYGA 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 498 QGIHVLQIVREAL-SNIYKHAQaTQVDITLQLRQGHIELSVADNGIGIPD-------------DASRANH-----YGLII 558
Cdd:PRK10604 315 LDMRLMERVLDNLlNNALRYAH-SRVRVSLLLDGNQACLIVEDDGPGIPPeerervfepfvrlDPSRDRAtggcgLGLAI 393
|
170 180 190
....*....|....*....|....*....|....*...
gi 506320711 559 MRDRARGLHGECIVRRRPSGGtevnvsflAEYRHRLPL 596
Cdd:PRK10604 394 VHSIALAMGGSVNCDESELGG--------ARFSFSWPV 423
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
502-547 |
2.52e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 37.79 E-value: 2.52e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 506320711 502 VLQIVREalsNIYKHA-----QATQVDITLQLRQGHIELSVADNGIGIPDD 547
Cdd:cd16957 5 ALQVLVE---NAIRHAfpkrkENNEVRVVVKKDQHKVHVSVSDNGQGIPEE 52
|
|
| PRK09793 |
PRK09793 |
methyl-accepting chemotaxis protein IV; |
46-279 |
3.88e-03 |
|
methyl-accepting chemotaxis protein IV;
Pssm-ID: 182079 [Multi-domain] Cd Length: 533 Bit Score: 40.05 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 46 AINKAGSLRMQSY------RLLSMVPLS-AENEIYLQELEEDEISSDLQQAVRRE---GLSEQFTAL--RVFWLEN--LQ 111
Cdd:PRK09793 66 ALNKAGTLTALSYpaddikTLMTTARASlTQSTTLFKSFMAMTAGNEHVRALQKEtekSFARWHNDLehQATWLESnqLS 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 112 PHLRQATHSSDASADVARFVKQLD--DLVSAIDHKTEQRLMMVTLVQRIFIGIMLILLITTFFYLRRRLLTPWRRLVSMA 189
Cdd:PRK09793 146 DFLTAPVQGSQNAFDVNFEAWQLEinHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHF 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 190 QAIGHGDFTQRVTINGHDEMSTLGQVLNSMsdelsamyhslEQRVAEKTADLQQknnllsflyrASRRLHTGaplCSRLM 269
Cdd:PRK09793 226 DSIAAGNLARPIAVYGRNEITAIFASLKTM-----------QQALRGTVSDVRK----------GSQEMHIG---IAEIV 281
|
250
....*....|
gi 506320711 270 PILNELSSLT 279
Cdd:PRK09793 282 AGNNDLSSRT 291
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
505-550 |
7.55e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 36.49 E-value: 7.55e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 506320711 505 IVREALSNIYKH-AQATQVDITLQLRQGHIELSVADNGIGIP-DDASR 550
Cdd:cd16948 9 IIGQIVSNALKYsKQGGKIEIYSETNEQGVVLSIKDFGIGIPeEDLPR 56
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
337-586 |
8.68e-03 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 38.67 E-value: 8.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 337 LHDKHGQYGVVLatlpgntalsrdqnqllntLLEQLTSTLALERQSNHQQQLMLMEEratIAREL-HD------SIAQSL 409
Cdd:COG3852 100 LRDAEGEGGVLL-------------------VLRDITERKRLERELRRAEKLAAVGE---LAAGLaHEirnpltGIRGAA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 410 SCLKIQVSclqmqggdlPPASQQLLTEMREELNTAYRQLRELLTTFRLKLSESGLL---AALRASVDEFSKRLGYPIELH 486
Cdd:COG3852 158 QLLERELP---------DDELREYTQLIIEEADRLNNLVDRLLSFSRPRPPEREPVnlhEVLERVLELLRAEAPKNIRIV 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506320711 487 YRLPPQ--SVSAHQGihvlQIvREALSNIYKHA-QA--------------TQVDITLQLRQGHIELSVADNGIGIPDDA- 548
Cdd:COG3852 229 RDYDPSlpEVLGDPD----QL-IQVLLNLVRNAaEAmpeggtitirtrveRQVTLGGLRPRLYVRIEVIDNGPGIPEEIl 303
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 506320711 549 ---------SRANHYGL-------IImrdraRGLHGECIVRRRPSGGTEVNVSF 586
Cdd:COG3852 304 drifepfftTKEKGTGLglaivqkIV-----EQHGGTIEVESEPGKGTTFRIYL 352
|
|
| |
