|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1043 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1533.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 1 MIEALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAK 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 81 TVRGFSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTALGPDATGVGWIYQYALVDRSGRHDLAQLRSLQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 161 DWFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSI 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 241 DDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRGIGELDGEGEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVE 320
Cdd:COG3696 241 EDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 321 IVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAI 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 401 GAMVDAAVVMIENAHKRVEAWHTRHPDTPlvgeqHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAF 480
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRAAGTPRE-----RLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMAL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 481 TKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEERsNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPLSRLGGE 560
Cdd:COG3696 475 TVIFALLGALLLSLTLVPVLASLLLRGKVPEKE-NPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 561 FLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMFESTIRFKPKSHWRPGM 640
Cdd:COG3696 554 FLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 641 TSEKLVEELDRVV-KVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVSSALAERLS 719
Cdd:COG3696 634 TKEELIAEMREALeQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 720 GGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYTAEGGQVTLG 799
Cdd:COG3696 714 GLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 800 SVARVSISEGPPMLKSENARLSGLVYVDVRGRDLASVVADLRQAVERDVHLAPGTSLSYSGQFEYLERANARLKLVVPAT 879
Cdd:COG3696 794 QVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 880 LAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLIYLKNARAEqprsd 959
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAE----- 948
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 960 dRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLRRRSLA 1039
Cdd:COG3696 949 -GLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLR 1027
|
....
gi 505315217 1040 NLPT 1043
Cdd:COG3696 1028 RAAA 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1036 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1315.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 1 MIEALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAK 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 81 TVRGFSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTALGPDATGVGWIYQYALVDRSG-------RHDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGarkkdggAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 154 AQLRSLQDWFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 234 SGYLKSIDDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKK 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 314 SLPAGVEIVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 394 GgiAIAIGAMVDAAVVMIENAHKRVEAWHTRHpDTPLVGEQHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGR 473
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEAQHHH-GRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 474 LFGPLAFTKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEErSNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWP 553
Cdd:TIGR00914 476 MFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEK-ENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWI 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 554 LSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMFESTIRFKPK 633
Cdd:TIGR00914 555 ASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPE 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 634 SHWRPG--MTSEKLVEELDRVVKVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVS 711
Cdd:TIGR00914 635 SQWPEGkkTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAA 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 712 SALAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYT- 790
Cdd:TIGR00914 715 DVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLp 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 791 ----AEGGQVTLGSVARVSISEGPPMLKSENARLSGLVYVDVRGRDLASVVADLRQAVERDVHLAPGTSLSYSGQFEYLE 866
Cdd:TIGR00914 795 lsedARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQ 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 867 RANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLI 946
Cdd:TIGR00914 875 SATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMIS 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 947 YLKNARAEQPRSDDratllrAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVI 1026
Cdd:TIGR00914 955 FIRKLLEEGPSLDE------AVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVL 1028
|
1050
....*....|.
gi 505315217 1027 PAAY-WLLRRR 1036
Cdd:TIGR00914 1029 PALYrLVHRRR 1039
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1034 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 717.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 5 LIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRG 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 85 FSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLP-ASAKTALGPDATGVGWIYQYALVDRSGRHDLAQLRSLQDWF 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPeGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 164 LRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSIDDF 243
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 244 RAVPLRLAgNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVT 323
Cdd:pfam00873 241 EKIIVKNQ-DGSPVRLRDVATVELGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 324 TYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAM 403
Cdd:pfam00873 319 VYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 404 VDAAVVMIENAHKRVEAwhtrhpdtplVGEQHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAFTKT 483
Cdd:pfam00873 399 VDDAIVVVENIERVLEE----------NGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIV 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 484 YAMAGAAGLSVTLVPVLMGYWIRGRLPEE------RSNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPLSRL 557
Cdd:pfam00873 469 LAILLSVLVALTLTPALCATLLKPRREPKhggffrWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 558 GGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESAtDPAPLEMFESTIRFKPKSHWR 637
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSG-DNNGPNSGDAFISLKPWKERP 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 638 -PGMTSEKLVEEL-DRVVKVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVSSALA 715
Cdd:pfam00873 628 gPEKSVQALIERLrKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 716 ERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYTAEGGQ 795
Cdd:pfam00873 708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKM 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 796 VTLGSVARVSISEGPPMLKSENARLSGLVYVDVRGRDLASVVADLRQAVERDVHLAPGTSLSYSGQFEYLERANARLKLV 875
Cdd:pfam00873 788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPIL 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 876 VPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLIYLKNARAEQ 955
Cdd:pfam00873 868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQE 947
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505315217 956 PRSddratLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLR 1034
Cdd:pfam00873 948 GKS-----LEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
7-1035 |
3.30e-119 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 390.92 E-value: 3.30e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 7 RWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFS 86
Cdd:NF033617 2 DVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 87 SFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKT-----ALGPDATGVGWIYQYalvdrSGRHDLAQLRSLQD 161
Cdd:NF033617 82 SLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDppvyrKANSADTPIMYIGLT-----SEEMPRGQLTDYAE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 162 WFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSID 241
Cdd:NF033617 157 RVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 242 DFRAVPLRLAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEI 321
Cdd:NF033617 237 DYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGV-PAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 322 VTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIG 401
Cdd:NF033617 316 NVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 402 AMVDAAVVMIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVGpalfFSLLIITLS----FIPVFTLEAQEGRLFGP 477
Cdd:NF033617 396 LVVDDAIVVVENIHRHIEE-----------GESPLEAALKGAREIG----FTVIAMTLTlvavYLPILFMGGLTGRLFRE 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 478 LAFTKTYAMAGAAGLSVTLVPVlMGYWIRGRLPEE-----RSNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLW 552
Cdd:NF033617 461 FAVTLAGAVIISGIVALTLTPM-MCSRLLKANEKPgrfarAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 553 PLSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMfestIRFKP 632
Cdd:NF033617 540 LYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGDNTGFGI----INLKP 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 633 ksHWRPGMTSEKLVEEL-DRVVKVPG--LTNIWIPPIRnridmLATGIKSPI-GVKIAGADLAEIERVAQAVERAARTVP 708
Cdd:NF033617 616 --WDERDVSAQEIIDRLrPKLAKVPGmdLFLFPLQDLP-----GGAGSSLPQyQVTLTPSDYDSLFTWAEKLKEKLRKSP 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 709 ---GVSSALAErlsGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRE 785
Cdd:NF033617 689 qfaDVDSDLQD---KGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQ 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 786 LPIYTAEGGQVTLGSVARVSISEGPPMLKSENARLSGLVYVDV-RGRDLASVVADLRQAVErdvHLAPGT-SLSYSGQFE 863
Cdd:NF033617 766 IYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLaPGVSLGEAIEALDQAAK---ELLPSGiSGSFQGAAR 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 864 YLERANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVI 943
Cdd:NF033617 843 AFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGIL 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 944 MLIYLKNARAEQprsddRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSL 1023
Cdd:NF033617 923 MVEFANELQRHQ-----GLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTL 997
|
1050
....*....|..
gi 505315217 1024 FVIPAAYWLLRR 1035
Cdd:NF033617 998 FVLPVVYLLLAR 1009
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
14-1047 |
6.93e-66 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 241.28 E-value: 6.93e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 14 LLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFSSFGDSFV 93
Cdd:PRK09579 12 VLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSII 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 94 YVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTAL----GPDATGVGWIYQYalvdrSGRHDLAQLRSLQDWFLRFELK 169
Cdd:PRK09579 92 SIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVlskeAADASALMYISFY-----SEEMSNPQITDYLSRVIQPKLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 170 TVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSIDDFRAVPLR 249
Cdd:PRK09579 167 TLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIPVK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 250 LAGNgSPVTLGDVASIQLGPEMRRGIGELDGEGEAVGGvIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVTTYDRSQ 329
Cdd:PRK09579 247 TSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIG-IKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 330 LIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMVDAAVV 409
Cdd:PRK09579 325 FIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIV 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 410 MIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVgpALFFSLLIITLS--FIPVFTLEAQEGRLFGPLAFTKTYAMA 487
Cdd:PRK09579 405 VVENIHRHIEE-----------GKSPFDAALEGAREI--AMPVVSMTITLAavYAPIGFLTGLTGALFKEFALTLAGAVI 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 488 GAAGLSVTLVPVLMGYWIRgrlPEErsNP------LNRWLIGL---YQPALERVLRyPRTTLAVAALIFLSSLWPLSRLG 558
Cdd:PRK09579 472 ISGIVALTLSPMMCALLLR---HEE--NPsglahrLDRLFERLkqrYQRALHGTLN-TRPVVLVFAVIVLALIPVLLKFT 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 559 GEFLPPLDEGDLLYMPSALPglSAQKAAELLQITDRLI---KSVPEVDTVFGKAGraesatdpapLEMFESTI---RFKP 632
Cdd:PRK09579 546 QSELAPEEDQGIIFMMSSSP--QPANLDYLNAYTDEFTpifKSFPEYYSSFQING----------FNGVQSGIggfLLKP 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 633 KSHwRPGMTSEKLVEELDRVVKVPGLTNIWIppirNRIDMLATGIKSPIGVKIAGA-DLAEIERVAQAVERAARTvPGVS 711
Cdd:PRK09579 614 WNE-RERTQMELLPLVQAKLEEIPGLQIFGF----NLPSLPGTGEGLPFQFVINTAnDYESLLQVAQRVKQRAQE-SGKF 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 712 SALAERLSGGR-YIDIDIDRQAAARYGLNIADVQAIVSGAIG-GENVGETLEGLArYPINVRYPREWRDSPEALRELPIY 789
Cdd:PRK09579 688 AFLDIDLAFDKpEVVVDIDRAKAAQMGVSMQDLGGTLATLLGeGEINRFTIDGRS-YKVIAQVERPYRDNPGWLNNYYVK 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 790 TAEGGQVTLGSVARVSISEGPPMLKS----ENARLSGLVYVDVrGRDLASVvadlrQAVERDvHLAPGTSLSYSG-QFEY 864
Cdd:PRK09579 767 NEQGQLLPLSTLITLSDRARPRQLNQfqqlNSAIISGFPIVSM-GEAIETV-----QQIARE-EAPEGFAFDYAGaSRQY 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 865 LERANArLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIM 944
Cdd:PRK09579 840 VQEGSA-LWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILI 918
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 945 LIYlknarAEQPRSDDRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLF 1024
Cdd:PRK09579 919 VEF-----ANQLRHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLF 993
|
1050 1060
....*....|....*....|...
gi 505315217 1025 VIPAAYWLLRRRSLANLPTDYPG 1047
Cdd:PRK09579 994 VLPCIYTLLAKPDAAPGVAQAAN 1016
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
3-414 |
3.69e-04 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 44.62 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 3 EALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPdLSDVQVIVRTsypGQAPQIVE----NQITYPLATTMLSVPG 78
Cdd:NF033617 513 GRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAP-SEDRGVIFGM---IQAPQSISldymSAKMRDVEKILSSDPE 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 79 AKTVRGFSSFG------DSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTAL----GPDATGVGW-IYQYALVDR 147
Cdd:NF033617 589 VQSLTSFNGVGgnpgdnTGFGIINLKPWDERDVSAQEIIDRLRPKLAKVPGMDLFLFplqdLPGGAGSSLpQYQVTLTPS 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 148 SgrhdlaqLRSLQDWF--LRFELKTVPDVAEVAS---VGGMvrQYQVLLDPLRLASLGITQSQVVEAIGKA--NRETGGG 220
Cdd:NF033617 669 D-------YDSLFTWAekLKEKLRKSPQFADVDSdlqDKGP--ELNVDIDRDKAARLGISMQDIGSTLEVAfgQRQVNTI 739
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 221 VLELGEAEFMVR-ASGYLKSIDDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRgIGELDGEGEAVGGViVLRSGKNARE 299
Cdd:NF033617 740 YTDGNQYKVVLEvDRRYRLNPEALNQIYVR-SNDGKLVPLSTLAKIEERAAPLS-LNHFNQFNSATLSF-NLAPGVSLGE 816
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 300 AIARVKDKLETLkksLPAGVeIVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLP---VGVLI 376
Cdd:NF033617 817 AIEALDQAAKEL---LPSGI-SGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPlagCGALL 892
|
410 420 430
....*....|....*....|....*....|....*...
gi 505315217 377 ALIVMHQQginANIMSLGGIAIAIGAMVDAAVVMIENA 414
Cdd:NF033617 893 ALALGGQS---MNIYAQIGLITLIGLVKKNGILMVEFA 927
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1043 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1533.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 1 MIEALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAK 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 81 TVRGFSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTALGPDATGVGWIYQYALVDRSGRHDLAQLRSLQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 161 DWFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSI 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 241 DDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRGIGELDGEGEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVE 320
Cdd:COG3696 241 EDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 321 IVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAI 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 401 GAMVDAAVVMIENAHKRVEAWHTRHPDTPlvgeqHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAF 480
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRAAGTPRE-----RLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMAL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 481 TKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEERsNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPLSRLGGE 560
Cdd:COG3696 475 TVIFALLGALLLSLTLVPVLASLLLRGKVPEKE-NPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 561 FLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMFESTIRFKPKSHWRPGM 640
Cdd:COG3696 554 FLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 641 TSEKLVEELDRVV-KVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVSSALAERLS 719
Cdd:COG3696 634 TKEELIAEMREALeQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 720 GGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYTAEGGQVTLG 799
Cdd:COG3696 714 GLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 800 SVARVSISEGPPMLKSENARLSGLVYVDVRGRDLASVVADLRQAVERDVHLAPGTSLSYSGQFEYLERANARLKLVVPAT 879
Cdd:COG3696 794 QVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 880 LAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLIYLKNARAEqprsd 959
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAE----- 948
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 960 dRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLRRRSLA 1039
Cdd:COG3696 949 -GLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLR 1027
|
....
gi 505315217 1040 NLPT 1043
Cdd:COG3696 1028 RAAA 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1036 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1315.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 1 MIEALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAK 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 81 TVRGFSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTALGPDATGVGWIYQYALVDRSG-------RHDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGarkkdggAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 154 AQLRSLQDWFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 234 SGYLKSIDDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKK 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 314 SLPAGVEIVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 394 GgiAIAIGAMVDAAVVMIENAHKRVEAWHTRHpDTPLVGEQHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGR 473
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEAQHHH-GRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 474 LFGPLAFTKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEErSNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWP 553
Cdd:TIGR00914 476 MFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEK-ENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWI 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 554 LSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMFESTIRFKPK 633
Cdd:TIGR00914 555 ASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPE 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 634 SHWRPG--MTSEKLVEELDRVVKVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVS 711
Cdd:TIGR00914 635 SQWPEGkkTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAA 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 712 SALAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYT- 790
Cdd:TIGR00914 715 DVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLp 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 791 ----AEGGQVTLGSVARVSISEGPPMLKSENARLSGLVYVDVRGRDLASVVADLRQAVERDVHLAPGTSLSYSGQFEYLE 866
Cdd:TIGR00914 795 lsedARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQ 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 867 RANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLI 946
Cdd:TIGR00914 875 SATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMIS 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 947 YLKNARAEQPRSDDratllrAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVI 1026
Cdd:TIGR00914 955 FIRKLLEEGPSLDE------AVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVL 1028
|
1050
....*....|.
gi 505315217 1027 PAAY-WLLRRR 1036
Cdd:TIGR00914 1029 PALYrLVHRRR 1039
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1034 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 717.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 5 LIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRG 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 85 FSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLP-ASAKTALGPDATGVGWIYQYALVDRSGRHDLAQLRSLQDWF 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPeGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 164 LRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSIDDF 243
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 244 RAVPLRLAgNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVT 323
Cdd:pfam00873 241 EKIIVKNQ-DGSPVRLRDVATVELGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 324 TYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAM 403
Cdd:pfam00873 319 VYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 404 VDAAVVMIENAHKRVEAwhtrhpdtplVGEQHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAFTKT 483
Cdd:pfam00873 399 VDDAIVVVENIERVLEE----------NGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIV 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 484 YAMAGAAGLSVTLVPVLMGYWIRGRLPEE------RSNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPLSRL 557
Cdd:pfam00873 469 LAILLSVLVALTLTPALCATLLKPRREPKhggffrWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 558 GGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESAtDPAPLEMFESTIRFKPKSHWR 637
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSG-DNNGPNSGDAFISLKPWKERP 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 638 -PGMTSEKLVEEL-DRVVKVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVSSALA 715
Cdd:pfam00873 628 gPEKSVQALIERLrKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 716 ERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYTAEGGQ 795
Cdd:pfam00873 708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKM 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 796 VTLGSVARVSISEGPPMLKSENARLSGLVYVDVRGRDLASVVADLRQAVERDVHLAPGTSLSYSGQFEYLERANARLKLV 875
Cdd:pfam00873 788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPIL 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 876 VPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLIYLKNARAEQ 955
Cdd:pfam00873 868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQE 947
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505315217 956 PRSddratLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLR 1034
Cdd:pfam00873 948 GKS-----LEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
5-1037 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 664.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 5 LIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRG 84
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 85 FSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAK----TALGPDATGVGWIyqyALvdRSGRHDLAQLRSLQ 160
Cdd:COG0841 83 TSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEppgvTKVNPSDFPVMVL---AL--SSDDLDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 161 DWFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSI 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 241 DDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVE 320
Cdd:COG0841 238 EEFENIVIR-TNDGSVVRLGDVARVEDGAEDYRSIARLNGK-PAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 321 IVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAI 400
Cdd:COG0841 316 LTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAI 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 401 GAMVDAAVVMIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAF 480
Cdd:COG0841 396 GIVVDDAIVVVENIERHMEE-----------GLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFAL 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 481 TKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEERS---NPLNR---WLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPL 554
Cdd:COG0841 465 TVAIALLISLFVALTLTPALCARLLKPHPKGKKGrffRAFNRgfdRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLF 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 555 SRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMFestIRFKPKS 634
Cdd:COG0841 545 GRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIF---VTLKPWD 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 635 HwRPgMTSEKLVEEL-DRVVKVPGLTNIWIPPirnriDMLATGIKSPIGVKIAGADLAEIERVAQAVERAARTVPGVSSA 713
Cdd:COG0841 622 E-RD-RSADEIIARLrEKLAKIPGARVFVFQP-----PAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDV 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 714 LAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYTAEG 793
Cdd:COG0841 695 RSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDG 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 794 GQVTLGSVARVSISEGPPMLKSENARLSGLVYVDV-RGRDLASVVADLRQAVERdVHLAPGTSLSYSGQFEYLERANARL 872
Cdd:COG0841 775 EMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLaPGVSLGEALAAIEELAAE-LKLPPGVSIEFTGQAEEEQESFSSL 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 873 KLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGvIMLI-YLKNA 951
Cdd:COG0841 854 GLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNA-ILLVdFANQL 932
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 952 RAEqprsddRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYW 1031
Cdd:COG0841 933 REE------GMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYV 1006
|
....*.
gi 505315217 1032 LLRRRS 1037
Cdd:COG0841 1007 LLDRLR 1012
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
7-1035 |
3.30e-119 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 390.92 E-value: 3.30e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 7 RWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFS 86
Cdd:NF033617 2 DVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 87 SFGDSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKT-----ALGPDATGVGWIYQYalvdrSGRHDLAQLRSLQD 161
Cdd:NF033617 82 SLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDppvyrKANSADTPIMYIGLT-----SEEMPRGQLTDYAE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 162 WFLRFELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSID 241
Cdd:NF033617 157 RVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 242 DFRAVPLRLAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEI 321
Cdd:NF033617 237 DYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGV-PAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 322 VTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIG 401
Cdd:NF033617 316 NVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 402 AMVDAAVVMIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVGpalfFSLLIITLS----FIPVFTLEAQEGRLFGP 477
Cdd:NF033617 396 LVVDDAIVVVENIHRHIEE-----------GESPLEAALKGAREIG----FTVIAMTLTlvavYLPILFMGGLTGRLFRE 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 478 LAFTKTYAMAGAAGLSVTLVPVlMGYWIRGRLPEE-----RSNPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLW 552
Cdd:NF033617 461 FAVTLAGAVIISGIVALTLTPM-MCSRLLKANEKPgrfarAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 553 PLSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMfestIRFKP 632
Cdd:NF033617 540 LYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGDNTGFGI----INLKP 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 633 ksHWRPGMTSEKLVEEL-DRVVKVPG--LTNIWIPPIRnridmLATGIKSPI-GVKIAGADLAEIERVAQAVERAARTVP 708
Cdd:NF033617 616 --WDERDVSAQEIIDRLrPKLAKVPGmdLFLFPLQDLP-----GGAGSSLPQyQVTLTPSDYDSLFTWAEKLKEKLRKSP 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 709 ---GVSSALAErlsGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRE 785
Cdd:NF033617 689 qfaDVDSDLQD---KGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQ 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 786 LPIYTAEGGQVTLGSVARVSISEGPPMLKSENARLSGLVYVDV-RGRDLASVVADLRQAVErdvHLAPGT-SLSYSGQFE 863
Cdd:NF033617 766 IYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLaPGVSLGEAIEALDQAAK---ELLPSGiSGSFQGAAR 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 864 YLERANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVI 943
Cdd:NF033617 843 AFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGIL 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 944 MLIYLKNARAEQprsddRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSL 1023
Cdd:NF033617 923 MVEFANELQRHQ-----GLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTL 997
|
1050
....*....|..
gi 505315217 1024 FVIPAAYWLLRR 1035
Cdd:NF033617 998 FVLPVVYLLLAR 1009
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
21-1036 |
1.35e-69 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 252.73 E-value: 1.35e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 21 LFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFS-SFGDSFVYVLFED 99
Cdd:TIGR00915 17 IIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdSDGSMTITLTFEQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 100 GTDLYWARSRVLEYLNQAQARLPASA-KTALGPDATGVGWIYQYALVDRSGRHDLAQLRSLQDWFLRFELKTVPDVAEVa 178
Cdd:TIGR00915 97 GTDPDIAQVQVQNKLQLATPLLPQEVqRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAASNMVDPLSRLEGVGDV- 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 179 SVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGvlELG--------EAEFMVRASGYLKSIDDFRAVPLRL 250
Cdd:TIGR00915 176 QLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAG--QLGglpavpgqQLNATIIAQTRLQTPEQFENILLKV 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 251 AGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVTTYDRSQL 330
Cdd:TIGR00915 254 NTDGSQVRLKDVARVELGGENYSISARFNGK-PASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGMKYVYPYDTTPF 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 331 IDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMVDAAVVM 410
Cdd:TIGR00915 333 VEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAIVV 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 411 IENAhKRVEAWHTRHPdtplvgeqhwRVMTEAAM-EVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAFTKTYAMAGA 489
Cdd:TIGR00915 413 VENV-ERVMAEEGLPP----------KEATRKSMgQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 490 AGLSVTLVPVL---MGYWIRGRLPEER----SNPLNR---WLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPLSRLGG 559
Cdd:TIGR00915 482 VLVALILTPALcatMLKPIEKGEHHEKkggfFGWFNRmfdSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 560 EFLPPLDEGDLLYMPSALPGLSAQKAAELL-QITDRLI-KSVPEVDTVFGKAGRAESATDPAPLEMFestIRFKPkshWR 637
Cdd:TIGR00915 562 SFLPDEDQGVFMTIVQLPAGATAERTQAVLaQVTKYLLaKEKANVESVFTVNGFSFAGRGQNMGMAF---IRLKD---WE 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 638 PGMTSEKLVEEldrvvkvpgltniwippIRNRIDMLATGIKSPIGVKIA-----------GADLAEIERVAQAVER---- 702
Cdd:TIGR00915 636 ERTGKENSVFA-----------------IAGRATGHFMQIKDAMVIAFVppailelgnatGFDFFLQDRAGLGHEAllqa 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 703 ------AARTVPGVSSALAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREW 776
Cdd:TIGR00915 699 rnqllgLAAQNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDA 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 777 RDSPEALRELPIYTAEGGQVTLGSVARVSISEGPPMLKsenaRLSGLVYVDVRGRDLASV-VADLRQAVERDV-HLAPGT 854
Cdd:TIGR00915 779 RMSPEDINKWYVRNASGEMVPFSAFATVRWEYGSPQLE----RYNGLPSMEILGSAAPGVsTGQAMAAMEAIAqKLPPGF 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 855 SLSYSGQfEYLER-ANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIAL 933
Cdd:TIGR00915 855 GFSWTGM-SYEERlSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTT 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 934 AGVAAEFGvIMLIYLKNARAEQPRSDDRATLlrairEGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVG 1013
Cdd:TIGR00915 934 IGLSAKNA-ILIVEFAKELMAQGKSIVEAAL-----EAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFG 1007
|
1050 1060
....*....|....*....|...
gi 505315217 1014 GMLTAPLLSLFVIPAAYWLLRRR 1036
Cdd:TIGR00915 1008 GMVTATVLAIFFVPLFYVVVRRL 1030
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
14-1047 |
6.93e-66 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 241.28 E-value: 6.93e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 14 LLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFSSFGDSFV 93
Cdd:PRK09579 12 VLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSII 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 94 YVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTAL----GPDATGVGWIYQYalvdrSGRHDLAQLRSLQDWFLRFELK 169
Cdd:PRK09579 92 SIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVlskeAADASALMYISFY-----SEEMSNPQITDYLSRVIQPKLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 170 TVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSIDDFRAVPLR 249
Cdd:PRK09579 167 TLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIPVK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 250 LAGNgSPVTLGDVASIQLGPEMRRGIGELDGEGEAVGGvIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVTTYDRSQ 329
Cdd:PRK09579 247 TSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIG-IKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 330 LIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMVDAAVV 409
Cdd:PRK09579 325 FIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIV 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 410 MIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVgpALFFSLLIITLS--FIPVFTLEAQEGRLFGPLAFTKTYAMA 487
Cdd:PRK09579 405 VVENIHRHIEE-----------GKSPFDAALEGAREI--AMPVVSMTITLAavYAPIGFLTGLTGALFKEFALTLAGAVI 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 488 GAAGLSVTLVPVLMGYWIRgrlPEErsNP------LNRWLIGL---YQPALERVLRyPRTTLAVAALIFLSSLWPLSRLG 558
Cdd:PRK09579 472 ISGIVALTLSPMMCALLLR---HEE--NPsglahrLDRLFERLkqrYQRALHGTLN-TRPVVLVFAVIVLALIPVLLKFT 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 559 GEFLPPLDEGDLLYMPSALPglSAQKAAELLQITDRLI---KSVPEVDTVFGKAGraesatdpapLEMFESTI---RFKP 632
Cdd:PRK09579 546 QSELAPEEDQGIIFMMSSSP--QPANLDYLNAYTDEFTpifKSFPEYYSSFQING----------FNGVQSGIggfLLKP 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 633 KSHwRPGMTSEKLVEELDRVVKVPGLTNIWIppirNRIDMLATGIKSPIGVKIAGA-DLAEIERVAQAVERAARTvPGVS 711
Cdd:PRK09579 614 WNE-RERTQMELLPLVQAKLEEIPGLQIFGF----NLPSLPGTGEGLPFQFVINTAnDYESLLQVAQRVKQRAQE-SGKF 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 712 SALAERLSGGR-YIDIDIDRQAAARYGLNIADVQAIVSGAIG-GENVGETLEGLArYPINVRYPREWRDSPEALRELPIY 789
Cdd:PRK09579 688 AFLDIDLAFDKpEVVVDIDRAKAAQMGVSMQDLGGTLATLLGeGEINRFTIDGRS-YKVIAQVERPYRDNPGWLNNYYVK 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 790 TAEGGQVTLGSVARVSISEGPPMLKS----ENARLSGLVYVDVrGRDLASVvadlrQAVERDvHLAPGTSLSYSG-QFEY 864
Cdd:PRK09579 767 NEQGQLLPLSTLITLSDRARPRQLNQfqqlNSAIISGFPIVSM-GEAIETV-----QQIARE-EAPEGFAFDYAGaSRQY 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 865 LERANArLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIM 944
Cdd:PRK09579 840 VQEGSA-LWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILI 918
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 945 LIYlknarAEQPRSDDRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLF 1024
Cdd:PRK09579 919 VEF-----ANQLRHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLF 993
|
1050 1060
....*....|....*....|...
gi 505315217 1025 VIPAAYWLLRRRSLANLPTDYPG 1047
Cdd:PRK09579 994 VLPCIYTLLAKPDAAPGVAQAAN 1016
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
20-1035 |
2.29e-62 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 230.89 E-value: 2.29e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 20 TLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFSSFGDSFVYVLFED 99
Cdd:PRK09577 16 SLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 100 GTDLYWARSRVLEYLNQAQARLPASAKTA---LGPDATGVGWIYqyALVDRSGRHDLAQLRSLQDWFLRFELKTVPDVAE 176
Cdd:PRK09577 96 GVNADLAAVEVQNRLKTVEARLPEPVRRDgiqVEKAADNIQLIV--SLTSDDGRLTGVELGEYASANVLQALRRVEGVGK 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 177 VASVGGmvrQYQVLL--DPLRLASLGITQSQVVEAIGKAN-RETGG-----GVLELGEAEFMVRASGYLKSIDDFRAVPL 248
Cdd:PRK09577 174 VQFWGA---EYAMRIwpDPVKLAALGLTASDIASAVRAHNaRVTIGdigrsAVPDSAPIAATVFADAPLKTPEDFGAIAL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 249 RLAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVTTYDRS 328
Cdd:PRK09577 251 RARADGSALYLRDVARIEFGGNDYNYPSYVNGK-TATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPYETS 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 329 QLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMVDAAV 408
Cdd:PRK09577 330 SFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILVDDAI 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 409 VMIENAhKRVEAWHTRHPdtplvgeqhWRVMTEAAMEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAFTKTYAMAG 488
Cdd:PRK09577 410 VVVENV-ERLMVEEGLSP---------YDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 489 AAGLSVTLVPVLMGYWIR---GRLPEERS-----NPLNRWLIGLYQPALERVLRYPRTTLAVAALIFLSSLWPLSRLGGE 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKpvdGDHHEKRGffgwfNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 561 FLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDPAPLEMFESTIRFKPKSHWRPGM 640
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAARDHV 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 641 TSekLVEELD-RVVKVPGLTNIWI--PPIRNridmlaTGIKSPIGVKIAGADLAEIERVAQAVER---AARTVPGVSSAL 714
Cdd:PRK09577 640 QA--IVARINeRFAGTPNTTVFAMnsPALPD------LGSTSGFDFRLQDRGGLGYAAFVAAREQllaEGAKDPALTDLM 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 715 AERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPIYTAEGG 794
Cdd:PRK09577 712 FAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGE 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 795 QVTLGSVARVSISEGPPMLksenARLSGLVYVDVRGRDLASVVA-DLRQAVERDVHLAP-GTSLSYSGQFEYLERANARL 872
Cdd:PRK09577 792 MVPLAAFATLHWTLGPPQL----TRYNGYPSFTINGSAAPGHSSgEAMAAIERIAATLPaGIGYAWSGQSFEERLSGAQA 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 873 KLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLIYLKNAR 952
Cdd:PRK09577 868 PMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLV 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 953 AEqprsddRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWL 1032
Cdd:PRK09577 948 AQ------RMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVV 1021
|
...
gi 505315217 1033 LRR 1035
Cdd:PRK09577 1022 VGR 1024
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
18-1036 |
1.35e-59 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 222.29 E-value: 1.35e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 18 LATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFSSFGDSFVYVLF 97
Cdd:PRK10614 16 LLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILQF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 98 EDGTDLYWARSRVLEYLNQAQARLPASAKT-----------------ALGPDATGVGWIYQYAlvdrSGRhdLAQlrslq 160
Cdd:PRK10614 96 DFDRDINGAARDVQAAINAAQSLLPSGMPSrptyrkanpsdapimilTLTSDTYSQGQLYDFA----STQ--LAQ----- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 161 dwflrfELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSI 240
Cdd:PRK10614 165 ------TISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 241 DDFRAVPLRLaGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVE 320
Cdd:PRK10614 239 AEYQPLIIHY-NNGAAVRLGDVATVTDSVQDVRNAGMTNAK-PAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAID 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 321 IVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAI 400
Cdd:PRK10614 317 LQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 401 GAMVDAAVVMIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVGpalfFSLLIITLS----FIPVFTLEAQEGRLFG 476
Cdd:PRK10614 397 GFVVDDAIVVLENISRHLEA-----------GMKPLQAALQGVREVG----FTVLSMSLSlvavFLPLLLMGGLPGRLFR 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 477 PLAFTKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEE--RSNPLNRWLIGL---YQPALERVLRYPRTTLAVAALIFLSSL 551
Cdd:PRK10614 462 EFAVTLSVAIGISLLVSLTLTPMMCAWLLKSSKPREqkRLRGFGRMLVALqqgYGRSLKWVLNHTRWVGVVLLGTIALNV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 552 WPLSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGRAESATDpaplEMFestIRFK 631
Cdd:PRK10614 542 WLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSG----MMF---ITLK 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 632 PKShwRPGMTSEKLVEEL-DRVVKVPGlTNIWIPPIRnriDMLATGIKSPIGVKIA--GADLAEIERVAQAVERAARTVP 708
Cdd:PRK10614 615 PLS--ERSETAQQVIDRLrVKLAKEPG-ANLFLMAVQ---DIRVGGRQSNASYQYTllSDDLAALREWEPKIRKALAALP 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 709 GVSSALAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRELPI 788
Cdd:PRK10614 689 ELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFV 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 789 YTAEGGQVTLGSVARvsisegppmLKSENARLSglvyVDVRGRDLASVVA----------DLRQAVERDVhLAPGTSLSY 858
Cdd:PRK10614 769 INNEGKAIPLSYFAK---------WQPANAPLS----VNHQGLSAASTISfnlptgkslsDASAAIERAM-TQLGVPSTV 834
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 859 SGQFE-----YLERANARLKLVVpATLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIAL 933
Cdd:PRK10614 835 RGSFAgtaqvFQETMNSQLILIL-AAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLL 913
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 934 AGVAAEFGVIMLIYlknarAEQPRSDDRATLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVG 1013
Cdd:PRK10614 914 IGIVKKNAIMMVDF-----ALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVG 988
|
1050 1060
....*....|....*....|....*.
gi 505315217 1014 GMLTAPLLSLFVIPAAYWL---LRRR 1036
Cdd:PRK10614 989 GLVMSQLLTLYTTPVVYLFfdrLRLR 1014
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
17-1036 |
1.78e-54 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 206.60 E-value: 1.78e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 17 LLATLFIVAwGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFSS-FGDSFVYV 95
Cdd:PRK10555 14 VLAILLCLT-GTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSgTGQASVTL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 96 LFEDGTDLYWARSRVLEYLNQAQARLPASAKT-ALGPDATGVGWIYQYALVDRSG---RHDLAQL--RSLQDwflrfELK 169
Cdd:PRK10555 93 SFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNqGVTVRKTGDTNILTIAFVSTDGsmdKQDIADYvaSNIQD-----PLS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 170 TVPDVAEVASVGGmvrQY--QVLLDPLRLASLGITQSQVVEAIGKANRETG----GGVLELGEAEF--MVRASGYLKSID 241
Cdd:PRK10555 168 RVNGVGDIDAYGS---QYsmRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAvgqlGGTPSVDKQALnaTINAQSLLQTPE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 242 DFRAVPLRLAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEI 321
Cdd:PRK10555 245 QFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGK-PASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLEY 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 322 VTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIG 401
Cdd:PRK10555 324 KVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 402 AMVDAAVVMIENahkrVEAWHTRHPDTPlvgeqhwRVMTEAAM-EVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAF 480
Cdd:PRK10555 404 LLVDDAIVVVEN----VERIMSEEGLTP-------REATRKSMgQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSI 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 481 TKTYAMAGAAGLSVTLVPVLMGYWIRGRLPEERSNplNRWLIGLYQPALER-VLRYPRTTLAVAA------LIFLSSL-- 551
Cdd:PRK10555 473 TIVSAMVLSVLVAMILTPALCATLLKPLKKGEHHG--QKGFFGWFNRMFNRnAERYEKGVAKILHrslrwiLIYVLLLgg 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 552 --WPLSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDR--LIKSVPEVDTVFGKAGRAESATDPAPLEMFest 627
Cdd:PRK10555 551 mvFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKyyFTHEKDNVMSVFATVGSGPGGNGQNVARMF--- 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 628 IRFKPkshW--RPGM--TSEKLVEELDRVVKVPGLTNIWI--PPIrnridmlATGIKSPIGVKIAGADLAEIERVAQAVE 701
Cdd:PRK10555 628 IRLKD---WdeRDSKtgTSFAIIERATKAFNKIKEARVIAssPPA-------ISGLGSSAGFDMELQDHAGAGHDALMAA 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 702 R-----AARTVPGVSSALAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREW 776
Cdd:PRK10555 698 RnqllaLAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPY 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 777 RDSPEALRELPIYTAEGGQVTLGSVARVSISEGPPMLKsenaRLSGLVYVDVRGRDLASVVADLRQAV-ERDVHLAP-GT 854
Cdd:PRK10555 778 RMLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLE----RYNGYSAVEIVGEAAPGVSTGTAMDImESLVKQLPnGF 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 855 SLSYSGQfEYLERANARLklvVPATLAIIFVLLYLTFGRVDEALLI----MATLPFALAGGVWLLYLMGYNLSIATGVGF 930
Cdd:PRK10555 854 GLEWTAM-SYQERLSGAQ---APALYAISLLVVFLCLAALYESWSVpfsvMLVVPLGVIGALLATWMRGLENDVYFQVGL 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 931 IALAGVAAEfGVIMLIYLKNARAEQPRSddratLLRAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVP 1010
Cdd:PRK10555 930 LTVIGLSAK-NAILIVEFANEMNQKGHD-----LFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTG 1003
|
1050 1060
....*....|....*....|....*.
gi 505315217 1011 MVGGMLTAPLLSLFVIPAAYWLLRRR 1036
Cdd:PRK10555 1004 VMGGMISATILAIFFVPLFFVLVRRR 1029
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
17-1036 |
1.35e-53 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 203.98 E-value: 1.35e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 17 LLATLFIVAWGLwSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFS-SFGDSFVYV 95
Cdd:PRK15127 14 VIAIIIMLAGGL-AILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQITL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 96 LFEDGTDLYWARSRVLEYLNQAQARLPASAKT-ALGPDATGVGWIYQYALVDRSGRHDLAQLRSLQDWFLRFELKTVPDV 174
Cdd:PRK15127 93 TFESGTDADIAQVQVQNKLQLAMPLLPQEVQQqGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTSGV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 175 AEVASVGGmvrQY--QVLLDPLRLASLGITQSQVVEAIGKANRETGGGvlELG--------EAEFMVRASGYLKSIDDFR 244
Cdd:PRK15127 173 GDVQLFGS---QYamRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAG--QLGgtppvkgqQLNASIIAQTRLTSTEEFG 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 245 AVPLRLAGNGSPVTLGDVASIQLGPEMRRGIGELDGEgEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVTT 324
Cdd:PRK15127 248 KILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQ-PASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 325 YDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMV 404
Cdd:PRK15127 327 YDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 405 DAAVVMIENAhKRVEAWHTRHPdtplvgeqhwRVMTEAAME-VGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAFTKT 483
Cdd:PRK15127 407 DDAIVVVENV-ERVMAEEGLPP----------KEATRKSMGqIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 484 YAMAGAAGLSVTLVPVLMGYWIR-------GRLPEERSNPLNRWL---IGLYQPALERVLRYPRTTLAVAALIFLSSLWP 553
Cdd:PRK15127 476 SAMALSVLVALILTPALCATMLKpiakgdhGEGKKGFFGWFNRMFeksTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 554 LSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAELL-QITDRLI----KSVPEVDTV--FGKAGRAESatdpaplemfeS 626
Cdd:PRK15127 556 FVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLnEVTDYYLtkekNNVESVFAVngFGFAGRGQN-----------T 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 627 TIRFKPKSHW--RPGMTSeklveeldrvvKVPGLTNIWIPPIRNRIDMLATGIKSPIGVKIAGADLAEIERVAQA----- 699
Cdd:PRK15127 625 GIAFVSLKDWadRPGEEN-----------KVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAglghe 693
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 700 -VERAARTVPGVSSALAERLSGGR--------YIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINV 770
Cdd:PRK15127 694 kLTQARNQLLGEAAKHPDMLVGVRpngledtpQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYV 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 771 RYPREWRDSPEALRELPIYTAEGGQVTLGSVARVSISEGPPMLKsenaRLSGLVYVDVRGRDLA--SVVADLRQAVERDV 848
Cdd:PRK15127 774 MSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLE----RYNGLPSMEILGQAAPgkSTGEAMELMEELAS 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 849 HLAPGTSLSYSGqFEYLERANARLklvVPATLAIIFVLLYLTFGRVDEALLI----MATLPFALAGGVWLLYLMGYNLSI 924
Cdd:PRK15127 850 KLPTGVGYDWTG-MSYQERLSGNQ---APALYAISLIVVFLCLAALYESWSIpfsvMLVVPLGVIGALLAATFRGLTNDV 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 925 ATGVGFIALAGVAAEFGVIMLIYLKNARAEQPRSDDRATLlrairEGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVM 1004
Cdd:PRK15127 926 YFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATL-----EAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQ 1000
|
1050 1060 1070
....*....|....*....|....*....|..
gi 505315217 1005 SRIAVPMVGGMLTAPLLSLFVIPAAYWLLRRR 1036
Cdd:PRK15127 1001 NAVGTGVMGGMVTATVLAIFFVPVFFVVVRRR 1032
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
20-1039 |
1.94e-52 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 200.34 E-value: 1.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 20 TLFIVAW---GLWSLRSTSIDALP--DLSDVQVIvrTSYPGQAPQIVENQITYPLATTMLSVPGAKTVRGFSSFGDSFVY 94
Cdd:PRK10503 24 TLLMVAIllaGIIGYRALPVSALPevDYPTIQVV--TLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVIT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 95 VLFEDGTDLYWARSRVLEYLNQAQARLP---------ASAKTALGPDATgvgwiyqyaLVDRSGRHDLAQLRSLQDWFLR 165
Cdd:PRK10503 102 LQFQLTLPLDVAEQEVQAAINAATNLLPsdlpnppvySKVNPADPPIMT---------LAVTSTAMPMTQVEDMVETRVA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 166 FELKTVPDVAEVASVGGMVRQYQVLLDPLRLASLGITQSQVVEAIGKANRETGGGVLELGEAEFMVRASGYLKSIDDFRA 245
Cdd:PRK10503 173 QKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 246 VPLRLAgNGSPVTLGDVASIQLGPEMRRgIGELDGEGEAVGGVIVLRSGKNAREAIARVKDKLETLKKSLPAGVEIVTTY 325
Cdd:PRK10503 253 LIIAYQ-NGAPIRLGDVATVEQGAENSW-LGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLS 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 326 DRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMVD 405
Cdd:PRK10503 331 DRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVD 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 406 AAVVMIENAHKRVEAwhtrhpdtplvGEQHWRVMTEAAMEVGpalffsLLIITLSF------IPVFTLEAQEGRLFGPLA 479
Cdd:PRK10503 411 DAIVVIENISRYIEK-----------GEKPLAAALKGAGEIG------FTIISLTFsliavlIPLLFMGDIVGRLFREFA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 480 FTKTYAMAGAAGLSVTLVPvLMGYWIRGRLPEERSNPLNR-------WLIGLYQPALERVLRYPRTTLAVA--ALIFLSS 550
Cdd:PRK10503 474 VTLAVAILISAVVSLTLTP-MMCARMLSQESLRKQNRFSRasermfdRVIAAYGRGLAKVLNHPWLTLSVAlsTLLLTVL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 551 LWPLSRLGgeFLPPLDEGDLLYMPSALPGLSAQKAAELLQITDRLIKSVPEVDTVFGKAGraESATDPApLEMFESTIRF 630
Cdd:PRK10503 553 LWIFIPKG--FFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG--VDGTNPS-LNSARLQINL 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 631 KPKSHwrpgmTSEKLVEELDR----VVKVPGLTnIWIPPIRN-RIDMLATgiKSPIGVKIAGADLAEIERVAQAVERAAR 705
Cdd:PRK10503 628 KPLDE-----RDDRVQKVIARlqtaVAKVPGVD-LYLQPTQDlTIDTQVS--RTQYQFTLQATSLDALSTWVPKLMEKLQ 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 706 TVPGVSSALAERLSGGRYIDIDIDRQAAARYGLNIADVQAIVSGAIGGENVGETLEGLARYPINVRYPREWRDSPEALRE 785
Cdd:PRK10503 700 QLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDT 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 786 LPIYTAEGGQVTLGSVARVSISEGPPMLKSENARLSGLVYVDVR-GRDLASVVADLRQAvERDVHLAPGTSLSYSGQFEY 864
Cdd:PRK10503 780 IRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPdGYSLGDAVQAIMDT-EKTLNLPADITTQFQGSTLA 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 865 LERA-NARLKLVVPATLAIIFVL--LYLTFgrvDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFG 941
Cdd:PRK10503 859 FQSAlGSTVWLIVAAVVAMYIVLgvLYESF---IHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNA 935
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 942 VIMLIYLKNARAEQ---PRSddratllrAIREGAVQRVRPKAMTVAVIVAGLLPILWGSGTGSEVMSRIAVPMVGGMLTA 1018
Cdd:PRK10503 936 IMMIDFALAAEREQgmsPRD--------AIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVS 1007
|
1050 1060
....*....|....*....|.
gi 505315217 1019 PLLSLFVIPAAYWLLRRRSLA 1039
Cdd:PRK10503 1008 QVLTLFTTPVIYLLFDRLALY 1028
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-420 |
5.87e-16 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 83.23 E-value: 5.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 3 EALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPDLSDVQVIVRTSYPGQAPQIVENQITYPLATTMLSVPGAKTV 82
Cdd:COG0841 516 GRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESV 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 83 R---GFSSFGDS----FVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTALGPDATGVGWIYQYALVDRSGrhDLAQ 155
Cdd:COG0841 596 FsvvGFSGGGSGsnsgTIFVTLKPWDERDRSADEIIARLREKLAKIPGARVFVFQPPAGGLGSGAPIEVQLQGD--DLEE 673
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 156 LRSLQDWFLRfELKTVPDVAEVASVGGM-VRQYQVLLDPLRLASLGITQSQVVEAIGKAnreTGG---GVLELGEAEF-- 229
Cdd:COG0841 674 LAAAAEKLLA-ALRQIPGLVDVRSDLQLgKPELQLDIDREKAAALGVTVADVASTLRAA---LGGryvNDFNRGGREYdv 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 230 MVRA-SGYLKSIDDFRAVPLRlAGNGSPVTLGDVASIqlgpEMRRGIGELDGEGE----AVGGVIVlrSGKNAREAIARV 304
Cdd:COG0841 750 RVQApEEDRNSPEDLENLYVR-TPDGEMVPLSSVATI----EEGTGPSSINRYNGqrsvTVSANLA--PGVSLGEALAAI 822
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 305 KDKLETLKksLPAGVEIVTTYDrSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLP---VGVLIALIVM 381
Cdd:COG0841 823 EELAAELK--LPPGVSIEFTGQ-AEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPlalIGALLGLLLT 899
|
410 420 430
....*....|....*....|....*....|....*....
gi 505315217 382 hqqGINANIMSLGGIAIAIGAMVDAAVVMIENAHKRVEA 420
Cdd:COG0841 900 ---GTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREE 935
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
831-1036 |
2.90e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 61.03 E-value: 2.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 831 RDLASVVADLRQAVERDVhlAPGTSLSYSGQF----EYLERANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPF 906
Cdd:COG1033 177 LDRKEVVAEIRAIIAKYE--DPGVEVYLTGFPvlrgDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLL 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 907 ALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIML-IYLKNARAEQPRSDdratllrAIREgAVQRV-RPKAMTVA 984
Cdd:COG1033 255 AVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLnRYREERRKGLDKRE-------ALRE-ALRKLgPPVLLTSL 326
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 505315217 985 VIVAGLLPILWgsgTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLRRR 1036
Cdd:COG1033 327 TTAIGFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRP 375
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
831-1028 |
3.71e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 57.54 E-value: 3.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 831 RDLASVVADLRQAVERDvHLAPGTSLSYSG----QFEYLERANARLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPF 906
Cdd:TIGR00921 151 KQVVPIYNDVERSLERT-NPPSGKFLDVTGspaiNYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILF 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 907 ALAGGVWLLYLMGYNLSIATGVGFIALAGVAAEFGVIMLIYLKNARAEQPRSDDraTLLRAIREGAVQRVRPKAMTVAVI 986
Cdd:TIGR00921 230 GVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGE--AIVTAVRRTGRAVLIALLTTSAGF 307
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 505315217 987 VAGLLPILwgsgtgsEVMSRIAVPMVGGMLTAPLLSLFVIPA 1028
Cdd:TIGR00921 308 AALALSEF-------PMVSEFGLGLVAGLITAYLLTLLVLPA 342
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
290-1036 |
1.90e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 55.25 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 290 VLRSGKNAREAIARVKDKLETLKKslpAGVEIVTT---YDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVA 366
Cdd:COG1033 172 PLSSDLDRKEVVAEIRAIIAKYED---PGVEVYLTgfpVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLP 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 367 IVSLPVGVLIALIVMHQQGINANIMS--LGGIAIAIGamVDAAVVMIENAHKRVEAWHTRHpdtplvgeqhwRVMTEAAM 444
Cdd:COG1033 249 LLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG--IDYGIHLLNRYREERRKGLDKR-----------EALREALR 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 445 EVGPALFFSLLIITLSFipvFTLeaqegrLFGPLAFTKTYAMAGAAG------LSVTLVPVLMGY---WIRGRLPEERSN 515
Cdd:COG1033 316 KLGPPVLLTSLTTAIGF---LSL------LFSDIPPIRDFGIVAAIGvllaflTSLTLLPALLSLlprPKPKTRRLKKPP 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 516 PLNRWLIGLyqpaLERVLRYPRTTLAVAALIFLSSLWPLSRLggeflppldegdllympsalpglsaqkaaellQITDRL 595
Cdd:COG1033 387 ELGRLLAKL----ARFVLRRPKVILVVALVLAVVSLYGISRL--------------------------------KVEYDF 430
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 596 IKSVPEvDTVFGKAgraesatdpaplemfestirfkpkshwrpgmtSEKLVEELDRVVKVpgltNIWIPPIRNRidmlat 675
Cdd:COG1033 431 EDYLPE-DSPIRQD--------------------------------LDFIEENFGGSDPL----EVVVDTGEPD------ 467
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 676 GIKSPigvkiagADLAEIERVAQAVEraarTVPGVSSALAerlsggryidididrqaaaryglnIADVQAIVSGAIGGEN 755
Cdd:COG1033 468 GLKDP-------EVLKEIDRLQDYLE----SLPEVGKVLS------------------------LADLVKELNQALNEGD 512
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 756 vgetleglaryPINVRYPrewrDSPEALRELPIYTAEGGQVTL-------GSVARVSISegppmlksenarlsglvYVDV 828
Cdd:COG1033 513 -----------PKYYALP----ESRELLAQLLLLLSSPPGDDLsrfvdedYSAARVTVR-----------------LKDL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 829 RGRDLASVVADLRQAVER-------DVHLApGTSLSYSGQFEYLERAnarLKLVVPATLAIIFVLLYLTFGRVDEALLIM 901
Cdd:COG1033 561 DSEEIKALVEEVRAFLAEnfppdgvEVTLT-GSAVLFAAINESVIES---QIRSLLLALLLIFLLLLLAFRSLRLGLISL 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 902 ATLPFALAGGVWLLYLMGYNLSIATGVGF-IALaGVAAEFGVIMLIYLKNARAEQPrsDDRATLLRAIRE--GAVqrvrp 978
Cdd:COG1033 637 IPNLLPILLTFGLMGLLGIPLNIATAVVAsIAL-GIGVDYTIHFLSRYREERRKGG--DLEEAIRRALRTtgKAI----- 708
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 505315217 979 kAMTVAVIVAGLLPILWGSGTGsevMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLRRR 1036
Cdd:COG1033 709 -LFTSLTLAAGFGVLLFSSFPP---LADFGLLLALGLLVALLAALLLLPALLLLLDPR 762
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
293-513 |
2.32e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 54.87 E-value: 2.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 293 SGKNAREAIARVKDKLETLKKSLPAGVEI----VTTYDrsqLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIV 368
Cdd:COG1033 561 DSEEIKALVEEVRAFLAENFPPDGVEVTLtgsaVLFAA---INESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLI 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 369 SLPVGVLIALIVMHQQGINANIMSLGGIAIAIGAMVDAAVVMIenaHKRVEAWHTRHPdtplvgeqHWRVMTEAAMEVGP 448
Cdd:COG1033 638 PNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFL---SRYREERRKGGD--------LEEAIRRALRTTGK 706
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505315217 449 ALFFSLLIITLSFIpVFTL---EAQegRLFGPL-AFTKTYAMAGAaglsVTLVPVLMgYWIRGRLPEER 513
Cdd:COG1033 707 AILFTSLTLAAGFG-VLLFssfPPL--ADFGLLlALGLLVALLAA----LLLLPALL-LLLDPRIAKKR 767
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
834-1038 |
1.53e-05 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 48.44 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 834 ASVVADLRQAVERDVHLAP------GTSLSYSGQFEYLERAnarLKLVVPATLAIIFVLLYLTFGRVDEALLIMATLPFA 907
Cdd:pfam03176 103 DESVAAVRDAVEQAPPPEGlkayltGPAATVADLRDAGDRD---LGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLS 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 908 LAGGVWLLYLMGYNLSI-----ATGVGFIALAGVAAEFGVIMLIYLKNARAEQPRSDDRAtlLRAIReGAVQRVRPKAMT 982
Cdd:pfam03176 180 LGAAQGLVAILAHILGIglstfALNLLVVLLIAVGTDYALFLVSRYREELRAGEDREEAV--IRAVR-GTGKVVTAAGLT 256
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 505315217 983 VAVIVAGLlpilwgSGTGSEVMSRIAVPMVGGMLTAPLLSLFVIPAAYWLLRRRSL 1038
Cdd:pfam03176 257 VAIAMLAL------SFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALLGRWGL 306
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
797-1036 |
2.16e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 45.14 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 797 TLGSVARVS--ISEGPPMLKSENARlSGLVYVDVRGRD---LASVVADLRQAVER------DVHLApGTSLSYSGQFEYL 865
Cdd:COG2409 90 ADPGVAGVQdpWDDPAAGLVSEDGK-AALVTVTLDGDAgdeAAEAVDALRDAVAAapapglTVYVT-GPAALAADLNEAF 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 866 ERANARLKLVvpaTLAIIFVLLYLTFGRVDEALLIMATLPFALAGGVWLLYLMGYNLSIATGVGFIALA---GVAAEFGv 942
Cdd:COG2409 168 EEDLGRAELI---TLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFTDVSSFAPNLLTMlglGVGIDYA- 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 943 imLIYLKNARAEQPRSDDRAT-LLRAIReGAVQRVRPKAMTVAVIVAGLLPilwgsgTGSEVMSRIAVPMVGGMLTAPLL 1021
Cdd:COG2409 244 --LFLVSRYREELRAGEDREEaVARAVA-TAGRAVLFSGLTVAIALLGLLL------AGLPFLRSMGPAAAIGVAVAVLA 314
|
250
....*....|....*
gi 505315217 1022 SLFVIPAAYWLLRRR 1036
Cdd:COG2409 315 ALTLLPALLALLGRR 329
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
3-414 |
3.69e-04 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 44.62 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 3 EALIRWSVANRLLVLLATLFIVAWGLWSLRSTSIDALPdLSDVQVIVRTsypGQAPQIVE----NQITYPLATTMLSVPG 78
Cdd:NF033617 513 GRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAP-SEDRGVIFGM---IQAPQSISldymSAKMRDVEKILSSDPE 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 79 AKTVRGFSSFG------DSFVYVLFEDGTDLYWARSRVLEYLNQAQARLPASAKTAL----GPDATGVGW-IYQYALVDR 147
Cdd:NF033617 589 VQSLTSFNGVGgnpgdnTGFGIINLKPWDERDVSAQEIIDRLRPKLAKVPGMDLFLFplqdLPGGAGSSLpQYQVTLTPS 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 148 SgrhdlaqLRSLQDWF--LRFELKTVPDVAEVAS---VGGMvrQYQVLLDPLRLASLGITQSQVVEAIGKA--NRETGGG 220
Cdd:NF033617 669 D-------YDSLFTWAekLKEKLRKSPQFADVDSdlqDKGP--ELNVDIDRDKAARLGISMQDIGSTLEVAfgQRQVNTI 739
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 221 VLELGEAEFMVR-ASGYLKSIDDFRAVPLRlAGNGSPVTLGDVASIQLGPEMRRgIGELDGEGEAVGGViVLRSGKNARE 299
Cdd:NF033617 740 YTDGNQYKVVLEvDRRYRLNPEALNQIYVR-SNDGKLVPLSTLAKIEERAAPLS-LNHFNQFNSATLSF-NLAPGVSLGE 816
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 300 AIARVKDKLETLkksLPAGVeIVTTYDRSQLIDRAVSNLGHKLLEEFIVVALVCAAFLWHLRSSLVAIVSLP---VGVLI 376
Cdd:NF033617 817 AIEALDQAAKEL---LPSGI-SGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPlagCGALL 892
|
410 420 430
....*....|....*....|....*....|....*...
gi 505315217 377 ALIVMHQQginANIMSLGGIAIAIGAMVDAAVVMIENA 414
Cdd:NF033617 893 ALALGGQS---MNIYAQIGLITLIGLVKKNGILMVEFA 927
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
836-1037 |
8.09e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 43.30 E-value: 8.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 836 VVADLRQAVERDVHLAPGTSLSYSGQFEYLERANARLK----LVVPATLAIIFVLLYLTFGRVdeALLIMATLPFALAG- 910
Cdd:COG4258 211 LVAALRAAFAALNAAFPGAQLLLTGAGLFAVAAAQQIKhdisTIGLISLLGILLLLLLVFRSL--RPLLLGLLPVAVGAl 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 911 -GVWLLYLMGYNLSIAT-GVGFiALAGVAAEFGVIMLIYLKNARAEQPRsddraTLLRAIRegavqrvRPKAMTVAVIVA 988
Cdd:COG4258 289 aGLAAVSLVFGSVHGITlGFGS-SLIGVAVDYSLHYLTHRRAAGEWDPR-----AALRRIW-------PTLLLGLLTTVL 355
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 505315217 989 GLLPILWgsgTGSEVMSRIAVPMVGGMLTAPLLSLFVIPaayWLLRRRS 1037
Cdd:COG4258 356 GYLALLF---SPFPGLRQLGVFAAAGLLAAALTTLLWLP---LLLPRAA 398
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
364-557 |
1.16e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.83 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 364 LVAIVSLPVGVLIALIVMHQQGINA---NIMSLGGIAIAIgamvDAAVVMIenahkrveawhTRHPDTPLVGEQHWRVMT 440
Cdd:COG2409 201 LTAGLAVGVALGLLALLAAFTDVSSfapNLLTMLGLGVGI----DYALFLV-----------SRYREELRAGEDREEAVA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505315217 441 EAAMEVGPALFFSLLIITLSFIpvftleaqeGRLFGPLAFTKTYAMAGAAG------LSVTLVPVLM---GYWI------ 505
Cdd:COG2409 266 RAVATAGRAVLFSGLTVAIALL---------GLLLAGLPFLRSMGPAAAIGvavavlAALTLLPALLallGRRVfwprrp 336
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505315217 506 -RGRLPEERSNPLNRWLiglyqpalERVLRYPRTTLAVAALIFLSSLWPLSRL 557
Cdd:COG2409 337 rRRRAAAPESGFWRRLA--------RAVVRRPVPVLVAAVAVLLALALPALGL 381
|
|
| |
