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Conserved domains on  [gi|505262905|ref|WP_015450007|]
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AAA family ATPase [Bifidobacterium thermophilum]

Protein Classification

AAA family ATPase( domain architecture ID 11437845)

AAA family ATPase similar to (d)CMP kinase, which catalyzes the phosphorylation of cytidine monophosphate (CMP) or dCMP to produce cytidine diphosphate (CDP) or dCDP, using ATP as the preferred phosphoryl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
8-196 3.26e-56

Cytidylate kinase [Nucleotide transport and metabolism];


:

Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 176.17  E-value: 3.26e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   8 IIITIGCEYGAGGPQIGKMLADALGIEYYDRDLVDKVVNQLGVSRGLVEQADQKTnvqyafeTSLGPRYANLSNRVIFTQ 87
Cdd:COG1102    1 MVITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKA-------PSLLYRDTAEEDEIDRAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905  88 SEVINDLAEKSSCVIIGRSANYLLRDRDDVLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRHKYITGTHR 167
Cdd:COG1102   74 DKVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYYKYYYGIDW 153

                        170       180
                 ....*....|....*....|....*....
gi 505262905 168 GDRSQRDLLLDTSLLGWDKTAKYLLMLVE 196
Cdd:COG1102  154 GDPSNYDLVINTSRLGIEEAVDLILAAIE 182
 
Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
8-196 3.26e-56

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 176.17  E-value: 3.26e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   8 IIITIGCEYGAGGPQIGKMLADALGIEYYDRDLVDKVVNQLGVSRGLVEQADQKTnvqyafeTSLGPRYANLSNRVIFTQ 87
Cdd:COG1102    1 MVITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKA-------PSLLYRDTAEEDEIDRAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905  88 SEVINDLAEKSSCVIIGRSANYLLRDRDDVLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRHKYITGTHR 167
Cdd:COG1102   74 DKVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYYKYYYGIDW 153

                        170       180
                 ....*....|....*....|....*....
gi 505262905 168 GDRSQRDLLLDTSLLGWDKTAKYLLMLVE 196
Cdd:COG1102  154 GDPSNYDLVINTSRLGIEEAVDLILAAIE 182
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
 9-180 2.70e-51

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 163.18  E-value: 2.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905    9 IITIGCEYGAGGPQIGKMLADALGIEYYDRDLVDKVVNQLGVSRGLVEQADQK---TNVQYAFETSLGPRYANLSNRVIF 85
Cdd:pfam13189   1 VITISRQYGSGGTTIAKKLAEKLGYPFYDREILDEIAKELGISEEEFELFDEKsrlSSFLYSLAGGRVRGDALSDDRLFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   86 TQSEVINDLAEKSSCVIIGRSANYLLRDRDDVLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRHKYITGT 165
Cdd:pfam13189  81 AQSKVIRELAAEDNCVIVGRGADYILKDIPNVLRVFLTAPLEDRVKRVMEREGLSEEEARELIKETDKRRAKYYKYYTGK 160

                         170
                  ....*....|....*
gi 505262905  166 HRGDRSQRDLLLDTS 180
Cdd:pfam13189 161 DWGDAENYDLVINTS 175
PRK04182 PRK04182
cytidylate kinase; Provisional
 9-192 1.63e-08

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 52.12  E-value: 1.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   9 IITIGCEYGAGGPQIGKMLADALGIEYYD-----RDLVDKvvnqLGVSrgLVE---QADQKTNVQYAfetslgpryanLS 80
Cdd:PRK04182   2 IITISGPPGSGKTTVARLLAEKLGLKHVSageifRELAKE----RGMS--LEEfnkYAEEDPEIDKE-----------ID 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905  81 NRVIftqsevinDLAEKSSCVII-GRSANYLLRDRDDvLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRH 159
Cdd:PRK04182  65 RRQL--------EIAEKEDNVVLeGRLAGWMAKDYAD-LKIWLKAPLEVRAERIAEREGISVEEALEETIEREESEAKRY 135

                        170       180       190
                 ....*....|....*....|....*....|...
gi 505262905 160 KYITGTHRGDRSQRDLLLDTSLLGWDKTAKYLL 192
Cdd:PRK04182 136 KEYYGIDIDDLSIYDLVINTSRWDPEGVFDIIL 168
 
Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
8-196 3.26e-56

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 176.17  E-value: 3.26e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   8 IIITIGCEYGAGGPQIGKMLADALGIEYYDRDLVDKVVNQLGVSRGLVEQADQKTnvqyafeTSLGPRYANLSNRVIFTQ 87
Cdd:COG1102    1 MVITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKA-------PSLLYRDTAEEDEIDRAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905  88 SEVINDLAEKSSCVIIGRSANYLLRDRDDVLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRHKYITGTHR 167
Cdd:COG1102   74 DKVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYYKYYYGIDW 153

                        170       180
                 ....*....|....*....|....*....
gi 505262905 168 GDRSQRDLLLDTSLLGWDKTAKYLLMLVE 196
Cdd:COG1102  154 GDPSNYDLVINTSRLGIEEAVDLILAAIE 182
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
 9-180 2.70e-51

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 163.18  E-value: 2.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905    9 IITIGCEYGAGGPQIGKMLADALGIEYYDRDLVDKVVNQLGVSRGLVEQADQK---TNVQYAFETSLGPRYANLSNRVIF 85
Cdd:pfam13189   1 VITISRQYGSGGTTIAKKLAEKLGYPFYDREILDEIAKELGISEEEFELFDEKsrlSSFLYSLAGGRVRGDALSDDRLFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   86 TQSEVINDLAEKSSCVIIGRSANYLLRDRDDVLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRHKYITGT 165
Cdd:pfam13189  81 AQSKVIRELAAEDNCVIVGRGADYILKDIPNVLRVFLTAPLEDRVKRVMEREGLSEEEARELIKETDKRRAKYYKYYTGK 160

                         170
                  ....*....|....*
gi 505262905  166 HRGDRSQRDLLLDTS 180
Cdd:pfam13189 161 DWGDAENYDLVINTS 175
PRK04182 PRK04182
cytidylate kinase; Provisional
 9-192 1.63e-08

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 52.12  E-value: 1.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905   9 IITIGCEYGAGGPQIGKMLADALGIEYYD-----RDLVDKvvnqLGVSrgLVE---QADQKTNVQYAfetslgpryanLS 80
Cdd:PRK04182   2 IITISGPPGSGKTTVARLLAEKLGLKHVSageifRELAKE----RGMS--LEEfnkYAEEDPEIDKE-----------ID 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505262905  81 NRVIftqsevinDLAEKSSCVII-GRSANYLLRDRDDvLDVFLYAPKDVRIASIMEQDHVDAKKAKEIVEYNDELNHSRH 159
Cdd:PRK04182  65 RRQL--------EIAEKEDNVVLeGRLAGWMAKDYAD-LKIWLKAPLEVRAERIAEREGISVEEALEETIEREESEAKRY 135

                        170       180       190
                 ....*....|....*....|....*....|...
gi 505262905 160 KYITGTHRGDRSQRDLLLDTSLLGWDKTAKYLL 192
Cdd:PRK04182 136 KEYYGIDIDDLSIYDLVINTSRWDPEGVFDIIL 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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