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Conserved domains on  [gi|505189202|ref|WP_015376304|]
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MULTISPECIES: SCP2 domain-containing protein [Serratia]

Protein Classification

SCP2 domain-containing protein( domain architecture ID 10006998)

SCP2 domain-containing protein similar to Escherichia coli ubiquinone biosynthesis protein UbiJ; the SCP2 domain which is involved in binding sterols

Gene Ontology:  GO:0032934

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UbiJ COG3165
Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism]; ...
2-202 3.53e-74

Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism];


:

Pssm-ID: 442398  Cd Length: 204  Bit Score: 222.43  E-value: 3.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202   2 LFTPLLTGALETSLNNLLFRDRSMKAARQRLAGKVLRIELEELASPLVLVFSELRVDVLGQSEDSADCTVRSRIPSLLKL 81
Cdd:COG3165    1 LLPPLLLAALETALNRLLALDPAARARLARLAGKVLRLELTELSLPLYLVFSEDGLDVLGAWEGEADCTLTGSLSALLRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202  82 RDRQQLPVLMRSGELTVEGDIQVVQQLVGLLDLAEWDPAEWLAPYIGDIAAQGITQALGKGASLLKAGFMRRQQDMAEAL 161
Cdd:COG3165   81 ADAQDLTALIASGELRIEGDAQLAQQLSRLLDQLDWDWEEDLSRYVGDVAAHRLAQGARKLLRWLRRAARRLQQNLAEYL 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 505189202 162 TEEWRLAPGPLEVVWFNEEVDALARSAEALIARMDKLEGKR 202
Cdd:COG3165  161 TEESRLLPGRLEVADFADEVDALRDDVDRLEARLARLEAKL 201
 
Name Accession Description Interval E-value
UbiJ COG3165
Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism]; ...
2-202 3.53e-74

Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism];


Pssm-ID: 442398  Cd Length: 204  Bit Score: 222.43  E-value: 3.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202   2 LFTPLLTGALETSLNNLLFRDRSMKAARQRLAGKVLRIELEELASPLVLVFSELRVDVLGQSEDSADCTVRSRIPSLLKL 81
Cdd:COG3165    1 LLPPLLLAALETALNRLLALDPAARARLARLAGKVLRLELTELSLPLYLVFSEDGLDVLGAWEGEADCTLTGSLSALLRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202  82 RDRQQLPVLMRSGELTVEGDIQVVQQLVGLLDLAEWDPAEWLAPYIGDIAAQGITQALGKGASLLKAGFMRRQQDMAEAL 161
Cdd:COG3165   81 ADAQDLTALIASGELRIEGDAQLAQQLSRLLDQLDWDWEEDLSRYVGDVAAHRLAQGARKLLRWLRRAARRLQQNLAEYL 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 505189202 162 TEEWRLAPGPLEVVWFNEEVDALARSAEALIARMDKLEGKR 202
Cdd:COG3165  161 TEESRLLPGRLEVADFADEVDALRDDVDRLEARLARLEAKL 201
SCP2 pfam02036
SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the ...
15-113 7.41e-21

SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the SCP2 protein as well as the C terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.


Pssm-ID: 460423 [Multi-domain]  Cd Length: 100  Bit Score: 82.69  E-value: 7.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202   15 LNNLLFRDRSMKAARQRLAGKVLRIELEELASPLVLVFSELRVDVLGQSEDSADCTVRSRIPSLLKLRDRQ-QLPVLMRS 93
Cdd:pfam02036   1 LNQLLARDPAARELLKKLNGKVIRFDLTDLGLSLTLDLKDGGGRVLAGDEGKADVTLSASDSDLLALATGKlNPQKAFMQ 80
                          90       100
                  ....*....|....*....|
gi 505189202   94 GELTVEGDIQVVQQLVGLLD 113
Cdd:pfam02036  81 GKLKIEGDMELAQKLEGLLK 100
 
Name Accession Description Interval E-value
UbiJ COG3165
Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism]; ...
2-202 3.53e-74

Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism];


Pssm-ID: 442398  Cd Length: 204  Bit Score: 222.43  E-value: 3.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202   2 LFTPLLTGALETSLNNLLFRDRSMKAARQRLAGKVLRIELEELASPLVLVFSELRVDVLGQSEDSADCTVRSRIPSLLKL 81
Cdd:COG3165    1 LLPPLLLAALETALNRLLALDPAARARLARLAGKVLRLELTELSLPLYLVFSEDGLDVLGAWEGEADCTLTGSLSALLRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202  82 RDRQQLPVLMRSGELTVEGDIQVVQQLVGLLDLAEWDPAEWLAPYIGDIAAQGITQALGKGASLLKAGFMRRQQDMAEAL 161
Cdd:COG3165   81 ADAQDLTALIASGELRIEGDAQLAQQLSRLLDQLDWDWEEDLSRYVGDVAAHRLAQGARKLLRWLRRAARRLQQNLAEYL 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 505189202 162 TEEWRLAPGPLEVVWFNEEVDALARSAEALIARMDKLEGKR 202
Cdd:COG3165  161 TEESRLLPGRLEVADFADEVDALRDDVDRLEARLARLEAKL 201
SCP2 pfam02036
SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the ...
15-113 7.41e-21

SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the SCP2 protein as well as the C terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.


Pssm-ID: 460423 [Multi-domain]  Cd Length: 100  Bit Score: 82.69  E-value: 7.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505189202   15 LNNLLFRDRSMKAARQRLAGKVLRIELEELASPLVLVFSELRVDVLGQSEDSADCTVRSRIPSLLKLRDRQ-QLPVLMRS 93
Cdd:pfam02036   1 LNQLLARDPAARELLKKLNGKVIRFDLTDLGLSLTLDLKDGGGRVLAGDEGKADVTLSASDSDLLALATGKlNPQKAFMQ 80
                          90       100
                  ....*....|....*....|
gi 505189202   94 GELTVEGDIQVVQQLVGLLD 113
Cdd:pfam02036  81 GKLKIEGDMELAQKLEGLLK 100
BDS1 COG2015
Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily [Secondary ...
54-113 3.44e-03

Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441618 [Multi-domain]  Cd Length: 629  Bit Score: 37.51  E-value: 3.44e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505189202  54 ELRVDVL----GQSEDSADCTVRSRIPSLLK-LRDRQQLPVLMRSGELTVEGDIQVVQQLVGLLD 113
Cdd:COG2015  556 ELRNGVLtyrkGPQADDADATLTLTRADLLAlLLGKTTLDDLVASGGAKVEGDAAALARLLGLLD 620
Alkyl_sulf_C pfam14864
Alkyl sulfatase C-terminal; This domain is found at the C-terminus of alkyl sulfatases. ...
54-116 7.69e-03

Alkyl sulfatase C-terminal; This domain is found at the C-terminus of alkyl sulfatases. Together with the N-terminal catalytic domain, this domain forms a hydrophobic chute and may recruit hydrophobic substrates.


Pssm-ID: 405542 [Multi-domain]  Cd Length: 124  Bit Score: 35.25  E-value: 7.69e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505189202   54 ELRVDVL----GQSEDSADCTVRSRIPSLLKLRDRQQ-LPVLMRSGELTVEGDIQVVQQLVGLLDLAE 116
Cdd:pfam14864  49 TLSNGVLtyrkGRQADDADATLTLTRADLLALLLGKAtLGKLIAAGKIKVEGDPSALAELLSLLDTFD 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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