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Conserved domains on  [gi|505177842|ref|WP_015364944|]
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MULTISPECIES: O-methyltransferase [Staphylococcus]

Protein Classification

O-methyltransferase( domain architecture ID 11467877)

O-methyltransferase of the class I-like SAM-binding methyltransferase superfamily, such as catechol O-methyltransferases that can use various catechol-like compounds

CATH:  2.20.25.110
EC:  2.1.1.-|2.1.-.-
Gene Ontology:  GO:0008757|GO:0032259|GO:1904047|GO:0008168|GO:0008171
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 36-209 3.60e-59

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 443298  Cd Length: 173  Bit Score: 183.46  E-value: 3.60e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  36 RNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFAS-VSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQF 114
Cdd:COG4122    2 PEQGRLLYLLARLLGAKRILEIGTGTGYSTLWLARaLPDDGRLTTIEIDPERAAIARENFARAGLADRIRLILGDALEVL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842 115 DKIKDQTFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDidivrSRNVRQMVKKVQQFNEWLMQQDGYT 194
Cdd:COG4122   82 PRLADGPFDLVFIDADKSNYPDYLELALPLLRPGGLIVADNVLWHGRVAD-----PARRDPSTRAIREFNEYLREDPRLE 156

                        170
                 ....*....|....*
gi 505177842 195 TNFLNMDDGLAISIK 209
Cdd:COG4122  157 SVLLPIGDGLLLARK 171
 
Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 36-209 3.60e-59

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 183.46  E-value: 3.60e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  36 RNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFAS-VSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQF 114
Cdd:COG4122    2 PEQGRLLYLLARLLGAKRILEIGTGTGYSTLWLARaLPDDGRLTTIEIDPERAAIARENFARAGLADRIRLILGDALEVL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842 115 DKIKDQTFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDidivrSRNVRQMVKKVQQFNEWLMQQDGYT 194
Cdd:COG4122   82 PRLADGPFDLVFIDADKSNYPDYLELALPLLRPGGLIVADNVLWHGRVAD-----PARRDPSTRAIREFNEYLREDPRLE 156

                        170
                 ....*....|....*
gi 505177842 195 TNFLNMDDGLAISIK 209
Cdd:COG4122  157 SVLLPIGDGLLLARK 171
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 19-209 6.96e-27

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 101.81  E-value: 6.96e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   19 IEALREYAVNHQVPI--VDRNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFA-SVSDDIQVTTIERNSEMIHQAKSNIS 95
Cdd:pfam01596  10 LKELREETAKLPLAPmqVSPDEGQFLGMLVKLTGAKNVLEIGVFTGYSALAMAlALPEDGKITAIDIDPEAYEIAKKFIQ 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   96 NNHYSHRIRLIEGDALEQFDKIKDQ----TFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDIDIVRSR 171
Cdd:pfam01596  90 KAGVAHKISFILGPALKVLEQLTQDkplpEFDFIFIDADKSNYPNYYERLLELLKVGGLMAIDNTLWHGKVTEPDDQEAK 169

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 505177842  172 NVRqmvkkVQQFNEWLMQQDGYTTNFLNMDDGLAISIK 209
Cdd:pfam01596 170 TQR-----LQEFNKDLAQDPRVEISVIPVGDGITLCRK 202
PLN02476 PLN02476
O-methyltransferase
 34-209 5.35e-20

O-methyltransferase


Pssm-ID: 178094  Cd Length: 278  Bit Score: 85.50  E-value: 5.35e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  34 VDRNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFASV-SDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALE 112
Cdd:PLN02476 102 VSPDQAQLLAMLVQILGAERCIEVGVYTGYSSLAVALVlPESGCLVACERDSNSLEVAKRYYELAGVSHKVNVKHGLAAE 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842 113 QFDKI----KDQTFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDIDIVRSRNVrqmvkKVQQFNEWLM 188
Cdd:PLN02476 182 SLKSMiqngEGSSYDFAFVDADKRMYQDYFELLLQLVRVGGVIVMDNVLWHGRVADPLVNDAKTI-----SIRNFNKKLM 256

                        170       180
                 ....*....|....*....|.
gi 505177842 189 QQDGYTTNFLNMDDGLAISIK 209
Cdd:PLN02476 257 DDKRVSISMVPIGDGMTICRK 277
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 53-153 4.20e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 57.83  E-value: 4.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  53 RILEIGTAIGYSAMQFASvSDDIQVTTIERNSEMIHQAKSNISNNHYsHRIRLIEGDAlEQFDKIKDQTFDMLFIDAA-- 130
Cdd:cd02440    1 RVLDLGCGTGALALALAS-GPGARVTGVDISPVALELARKAAAALLA-DNVEVLKGDA-EELPPEADESFDVIISDPPlh 77

                         90       100
                 ....*....|....*....|....*
gi 505177842 131 --KAQSKKFFELYTPLLREGGIVIT 153
Cdd:cd02440   78 hlVEDLARFLEEARRLLKPGGVLVL 102
methyltr_grsp TIGR04188
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are ...
 53-111 7.63e-04

methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).


Pssm-ID: 275041  Cd Length: 363  Bit Score: 39.65  E-value: 7.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 505177842   53 RILEIGTAIGYSAMQFASVSDDIQVTTIERNSEMIHQAKSNISnnHYSHRIRLIEGDAL 111
Cdd:TIGR04188 110 RVLEIGTGTGYSAALLCHRLGDDNVTSVEVDPGLAARAASALA--AAGYAPTVVTGDGL 166
 
Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 36-209 3.60e-59

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 183.46  E-value: 3.60e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  36 RNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFAS-VSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQF 114
Cdd:COG4122    2 PEQGRLLYLLARLLGAKRILEIGTGTGYSTLWLARaLPDDGRLTTIEIDPERAAIARENFARAGLADRIRLILGDALEVL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842 115 DKIKDQTFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDidivrSRNVRQMVKKVQQFNEWLMQQDGYT 194
Cdd:COG4122   82 PRLADGPFDLVFIDADKSNYPDYLELALPLLRPGGLIVADNVLWHGRVAD-----PARRDPSTRAIREFNEYLREDPRLE 156

                        170
                 ....*....|....*
gi 505177842 195 TNFLNMDDGLAISIK 209
Cdd:COG4122  157 SVLLPIGDGLLLARK 171
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 19-209 6.96e-27

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 101.81  E-value: 6.96e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   19 IEALREYAVNHQVPI--VDRNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFA-SVSDDIQVTTIERNSEMIHQAKSNIS 95
Cdd:pfam01596  10 LKELREETAKLPLAPmqVSPDEGQFLGMLVKLTGAKNVLEIGVFTGYSALAMAlALPEDGKITAIDIDPEAYEIAKKFIQ 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   96 NNHYSHRIRLIEGDALEQFDKIKDQ----TFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDIDIVRSR 171
Cdd:pfam01596  90 KAGVAHKISFILGPALKVLEQLTQDkplpEFDFIFIDADKSNYPNYYERLLELLKVGGLMAIDNTLWHGKVTEPDDQEAK 169

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 505177842  172 NVRqmvkkVQQFNEWLMQQDGYTTNFLNMDDGLAISIK 209
Cdd:pfam01596 170 TQR-----LQEFNKDLAQDPRVEISVIPVGDGITLCRK 202
PLN02476 PLN02476
O-methyltransferase
 34-209 5.35e-20

O-methyltransferase


Pssm-ID: 178094  Cd Length: 278  Bit Score: 85.50  E-value: 5.35e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  34 VDRNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFASV-SDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALE 112
Cdd:PLN02476 102 VSPDQAQLLAMLVQILGAERCIEVGVYTGYSSLAVALVlPESGCLVACERDSNSLEVAKRYYELAGVSHKVNVKHGLAAE 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842 113 QFDKI----KDQTFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDIDIVRSRNVrqmvkKVQQFNEWLM 188
Cdd:PLN02476 182 SLKSMiqngEGSSYDFAFVDADKRMYQDYFELLLQLVRVGGVIVMDNVLWHGRVADPLVNDAKTI-----SIRNFNKKLM 256

                        170       180
                 ....*....|....*....|.
gi 505177842 189 QQDGYTTNFLNMDDGLAISIK 209
Cdd:PLN02476 257 DDKRVSISMVPIGDGMTICRK 277
Methyltransf_24 pfam13578
Methyltransferase domain; This family appears to be a methyltransferase domain.
 55-156 4.77e-17

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 433324 [Multi-domain]  Cd Length: 106  Bit Score: 73.50  E-value: 4.77e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   55 LEIGTAIGYSAMQFASVSDD---IQVTTIERNsEMIHQAKSNISNNHYSHRIRLIEGDALEQFDKIKDQTFDMLFIDA-- 129
Cdd:pfam13578   1 VEIGTYSGVSTLWLAAALRDnglGRLTAVDPD-PGAEEAGALLRKAGLDDRVRLIVGDSREALPSLADGPIDLLFIDGdh 79

                          90       100
                  ....*....|....*....|....*..
gi 505177842  130 AKAQSKKFFELYTPLLREGGIVITDNV 156
Cdd:pfam13578  80 TYEAVLNDLELWLPRLAPGGVILFHDI 106
PLN02781 PLN02781
Probable caffeoyl-CoA O-methyltransferase
 31-187 1.57e-14

Probable caffeoyl-CoA O-methyltransferase


Pssm-ID: 215417  Cd Length: 234  Bit Score: 69.84  E-value: 1.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  31 VPIVDRNTLEMIKQIIrinHTTRILEIGTAIGYSAMQFA-SVSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGD 109
Cdd:PLN02781  52 VPVDEGLFLSMLVKIM---NAKNTLEIGVFTGYSLLTTAlALPEDGRITAIDIDKEAYEVGLEFIKKAGVDHKINFIQSD 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842 110 ALEQFDKI----KDQTFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHGFVSDIDIVRSRNVRQMVKKVQQFNE 185
Cdd:PLN02781 129 ALSALDQLlnndPKPEFDFAFVDADKPNYVHFHEQLLKLVKVGGIIAFDNTLWFGFVAQEEDEVPEHMRAYRKALLEFNK 208


                 ..
gi 505177842 186 WL 187
Cdd:PLN02781 209 LL 210
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 46-124 1.75e-11

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 61.31  E-value: 1.75e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505177842  46 IRINHTTRILEIGTAIGYSAMQFASVSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQFDKIKDQTFDM 124
Cdd:COG4123   33 APVKKGGRVLDLGTGTGVIALMLAQRSPGARITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKEFAAELPPGSFDL 111
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 53-153 4.20e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 57.83  E-value: 4.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  53 RILEIGTAIGYSAMQFASvSDDIQVTTIERNSEMIHQAKSNISNNHYsHRIRLIEGDAlEQFDKIKDQTFDMLFIDAA-- 130
Cdd:cd02440    1 RVLDLGCGTGALALALAS-GPGARVTGVDISPVALELARKAAAALLA-DNVEVLKGDA-EELPPEADESFDVIISDPPlh 77

                         90       100
                 ....*....|....*....|....*
gi 505177842 131 --KAQSKKFFELYTPLLREGGIVIT 153
Cdd:cd02440   78 hlVEDLARFLEEARRLLKPGGVLVL 102
PLN02589 PLN02589
caffeoyl-CoA O-methyltransferase
 19-206 1.40e-10

caffeoyl-CoA O-methyltransferase


Pssm-ID: 166230  Cd Length: 247  Bit Score: 58.85  E-value: 1.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  19 IEALREYAVNHQVPIVDRNTLE--MIKQIIRINHTTRILEIGTAIGYSAMQFA-SVSDDIQVTTIERNSEMIHQAKSNIS 95
Cdd:PLN02589  46 MKELRELTAKHPWNIMTTSADEgqFLNMLLKLINAKNTMEIGVYTGYSLLATAlALPEDGKILAMDINRENYELGLPVIQ 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  96 NNHYSHRIRLIEGDALEQFDK-IKDQ----TFDMLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLYHG-FVSDIDIVR 169
Cdd:PLN02589 126 KAGVAHKIDFREGPALPVLDQmIEDGkyhgTFDFIFVDADKDNYINYHKRLIDLVKVGGVIGYDNTLWNGsVVAPPDAPM 205

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 505177842 170 SRNVRQMVKKVQQFNEWLMQQDGYTTNFLNMDDGLAI 206
Cdd:PLN02589 206 RKYVRYYRDFVLELNKALAADPRIEICMLPVGDGITL 242
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
29-152 1.16e-09

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 56.20  E-value: 1.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  29 HQVPIVDRNTLEMIKQIIR--INHTTRILEIGTAIGYSAMqFASVSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLI 106
Cdd:COG4076   12 HHPMLNDVERNDAFKAAIErvVKPGDVVLDIGTGSGLLSM-LAARAGAKKVYAVEVNPDIAAVARRIIAANGLSDRITVI 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 505177842 107 EGDAL-----EQFDKIKDQTFDMLFIDAakAQSKKFFELYTPLLREGGIVI 152
Cdd:COG4076   91 NADATdldlpEKADVIISEMLDTALLDE--GQVPILNHARKRLLKPGGRII 139
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 20-117 1.55e-09

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 55.09  E-value: 1.55e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  20 EALREYA-VNHQVPIVDRNTLE-------MIkQIIRINHTTRILEIGTAIGYSA---MQFASvsddiQVTTIERNSEMIH 88
Cdd:COG2518   29 EALRELAyADRALPIGHGQTISqpyivarML-EALDLKPGDRVLEIGTGSGYQAavlARLAG-----RVYSVERDPELAE 102

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 505177842  89 QAKSNISNNHYsHRIRLIEGDALE------QFDKI 117
Cdd:COG2518  103 RARERLAALGY-DNVTVRVGDGALgwpehaPFDRI 136
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 53-128 3.92e-08

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 52.08  E-value: 3.92e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505177842  53 RILEIGTAIGYSAMQFAS-VSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQFDkikDQTFDMLFID 128
Cdd:COG2519   94 RVLEAGTGSGALTLALARaVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKLGDIREGID---EGDVDAVFLD 167
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 44-180 1.73e-07

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 48.84  E-value: 1.73e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  44 QIIRINHTTRILEIGTAIGYSAMQFAsvSDDIQVTTIERNSEMIHQAKSNISNNHYshRIRLIEGDAlEQFDkIKDQTFD 123
Cdd:COG2226   16 AALGLRPGARVLDLGCGTGRLALALA--ERGARVTGVDISPEMLELARERAAEAGL--NVEFVVGDA-EDLP-FPDGSFD 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505177842 124 MLFI--------DAAKAqskkFFELYTpLLREGGIVItdnvlyhgfVSDIDIVRSRNVRQMVKKV 180
Cdd:COG2226   90 LVISsfvlhhlpDPERA----LAEIAR-VLKPGGRLV---------VVDFSPPDLAELEELLAEA 140
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 52-200 4.50e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 47.80  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   52 TRILEIGTAIGYSAMQFAS-VSDDIQVTTIERNSEMIHQAKSNISNNHYShRIRLIEGDALEQFDKIKDQTFDMLFIDAA 130
Cdd:pfam13847   5 MRVLDLGCGTGHLSFELAEeLGPNAEVVGIDISEEAIEKARENAQKLGFD-NVEFEQGDIEELPELLEDDKFDVVISNCV 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505177842  131 KAQSK---KFFELYTPLLREGGIVITDnvlyhgfvsdiDIVRSRNVRQMVKKVQQFNEWLMQQDGYTTNFLNM 200
Cdd:pfam13847  84 LNHIPdpdKVLQEILRVLKPGGRLIIS-----------DPDSLAELPAHVKEDSTYYAGCVGGAILKKKLYEL 145
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 33-158 8.57e-07

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 47.60  E-value: 8.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  33 IVDRNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFASvSDDIQVTTIERNSEMIHQAKSNISNNHYSHrIRLIEGDaLE 112
Cdd:COG0500    9 ELLPGLAALLALLERLPKGGRVLDLGCGTGRNLLALAA-RFGGRVIGIDLSPEAIALARARAAKAGLGN-VEFLVAD-LA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 505177842 113 QFDKIKDQTFD-----MLFIDAAKAQSKKFFELYTPLLREGGIVITDNVLY 158
Cdd:COG0500   86 ELDPLPAESFDlvvafGVLHHLPPEEREALLRELARALKPGGVLLLSASDA 136
COG2521 COG2521
Predicted archaeal methyltransferase [General function prediction only];
32-169 1.38e-06

Predicted archaeal methyltransferase [General function prediction only];


Pssm-ID: 442011 [Multi-domain]  Cd Length: 285  Bit Score: 47.60  E-value: 1.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  32 PIVDRN----TLEMIKQIiRINHTTRILEIGTAIGYSAMQFASVSDDiQVTTIERNSEMIHQAKSN-ISNNHYSHRIRLI 106
Cdd:COG2521  111 RIKGTDpledARRKVKLV-GVRRGDRVLDTCTGLGYTAIEALKRGAR-EVITVEKDPNVLELAELNpWSRELANERIKII 188

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505177842 107 EGDALEQFDKIKDQTFDMLFIDA---AKAQ---SKKFF-ELYTpLLREGGIvitdnvLYH------GFVSDIDIVR 169
Cdd:COG2521  189 LGDASEVIKTFPDESFDAIIHDPprfSLAGelySLEFYrELYR-VLKPGGR------LFHytgnpgKKKRGRDVPR 257
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 54-149 3.23e-06

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 44.09  E-value: 3.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   54 ILEIGTAIGYSAMQFASvSDDIQVTTIERNSEMIHQAKSNISNNHysHRIRLIEGDAlEQFDkIKDQTFDMLFIDAA--- 130
Cdd:pfam13649   1 VLDLGCGTGRLTLALAR-RGGARVTGVDLSPEMLERARERAAEAG--LNVEFVQGDA-EDLP-FPDGSFDLVVSSGVlhh 75

                          90       100
                  ....*....|....*....|..
gi 505177842  131 --KAQSKKFF-ELYTpLLREGG 149
Cdd:pfam13649  76 lpDPDLEAALrEIAR-VLKPGG 96
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 36-152 7.35e-06

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 44.54  E-value: 7.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  36 RNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFASvSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDAL---- 111
Cdd:COG2230   37 EAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLAR-RYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRdlpa 115

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 505177842 112 -EQFDKIkdqtfdmLFIDAA----KAQSKKFFELYTPLLREGGIVI 152
Cdd:COG2230  116 dGQFDAI-------VSIGMFehvgPENYPAYFAKVARLLKPGGRLL 154
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 46-157 2.29e-05

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 43.63  E-value: 2.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  46 IRINHTTRILEIGTAIGYSAMQFA-SVSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQFDKIKDQtFDM 124
Cdd:PRK00377  36 LRLRKGDMILDIGCGTGSVTVEASlLVGETGKVYAVDKDEKAINLTRRNAEKFGVLNNIVLIKGEAPEILFTINEK-FDR 114

                         90       100       110
                 ....*....|....*....|....*....|...
gi 505177842 125 LFIDAAKAQSKKFFELYTPLLREGGIVITDNVL 157
Cdd:PRK00377 115 IFIGGGSEKLKEIISASWEIIKKGGRIVIDAIL 147
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
53-130 2.43e-05

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 41.73  E-value: 2.43e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505177842  53 RILEIGTAIGYSAMQFASVSDDIQVTTIERNSEMIHQAKSNISNnhyshrIRLIEGDAlEQFDkiKDQTFDMLFIDAA 130
Cdd:COG4106    4 RVLDLGCGTGRLTALLAERFPGARVTGVDLSPEMLARARARLPN------VRFVVADL-RDLD--PPEPFDLVVSNAA 72
pcm PRK00312
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
20-152 4.21e-05

protein-L-isoaspartate(D-aspartate) O-methyltransferase;


Pssm-ID: 178974 [Multi-domain]  Cd Length: 212  Bit Score: 42.88  E-value: 4.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  20 EALREYA-VNHQVPIVDRNTLE-------MIkQIIRINHTTRILEIGTAIGYSAMQFASVSDDiqVTTIERNSEMIHQAK 91
Cdd:PRK00312  41 EAFKHKAyENRALPIGCGQTISqpymvarMT-ELLELKPGDRVLEIGTGSGYQAAVLAHLVRR--VFSVERIKTLQWEAK 117

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  92 SN-----ISNNHyshrIRLIEGD----ALEQFDKIkdqtfdmLFIDAAKAQSKKFFElytpLLREGGIVI 152
Cdd:PRK00312 118 RRlkqlgLHNVS----VRHGDGWkgwpAYAPFDRI-------LVTAAAPEIPRALLE----QLKEGGILV 172
PRK14968 PRK14968
putative methyltransferase; Provisional
 40-126 1.05e-04

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 41.42  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  40 EMIKQIIRINHTTRILEIGTAIGYSAMQFAsvSDDIQVTTIERNSEMIHQAKSNISNNHYSHR-IRLIEGDAleqFDKIK 118
Cdd:PRK14968  13 FLLAENAVDKKGDRVLEVGTGSGIVAIVAA--KNGKKVVGVDINPYAVECAKCNAKLNNIRNNgVEVIRSDL---FEPFR 87


                 ....*....
gi 505177842 119 DQTFD-MLF 126
Cdd:PRK14968  88 GDKFDvILF 96
methyltr_grsp TIGR04188
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are ...
 53-111 7.63e-04

methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).


Pssm-ID: 275041  Cd Length: 363  Bit Score: 39.65  E-value: 7.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 505177842   53 RILEIGTAIGYSAMQFASVSDDIQVTTIERNSEMIHQAKSNISnnHYSHRIRLIEGDAL 111
Cdd:TIGR04188 110 RVLEIGTGTGYSAALLCHRLGDDNVTSVEVDPGLAARAASALA--AAGYAPTVVTGDGL 166
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 42-123 8.43e-04

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 38.07  E-value: 8.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  42 IKQIIR--INHTTRILEIGTAIGYSAMQFASVsdDIQVTTIERNSEMIHQAKSNISnnhySHRIRLIEGDaLEQFDkIKD 119
Cdd:COG2227   14 LAALLArlLPAGGRVLDVGCGTGRLALALARR--GADVTGVDISPEALEIARERAA----ELNVDFVQGD-LEDLP-LED 85


                 ....
gi 505177842 120 QTFD 123
Cdd:COG2227   86 GSFD 89
SpeE COG0421
Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];
53-153 1.06e-03

Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];


Pssm-ID: 440190 [Multi-domain]  Cd Length: 195  Bit Score: 38.66  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  53 RILEIGTAIGYSAMQFASVSDDIQVTTIERNSEMIHQAKS---NISNNHYSHRIRLIEGDALEqFDKIKDQTFDMLFIDA 129
Cdd:COG0421   40 RVLIIGGGDGGLARELLKHPPVERVDVVEIDPEVVELAREyfpLLAPAFDDPRLRVVIGDGRA-FLREAEESYDVIIVDL 118

                         90       100       110
                 ....*....|....*....|....*....|.
gi 505177842 130 ------AKAQ-SKKFFELYTPLLREGGIVIT 153
Cdd:COG0421  119 tdpvgpAEGLfTREFYEDCRRALKPGGVLVV 149
RsmA COG0030
16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase ...
 33-112 1.39e-03

16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) [Translation, ribosomal structure and biogenesis]; 16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 439801 [Multi-domain]  Cd Length: 270  Bit Score: 38.57  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  33 IVDRNTLEMIKQIIRINHTTRILEIGTAIGysAM--QFASVSDdiQVTTIERNSEMIHQAKSNISNNhysHRIRLIEGDA 110
Cdd:COG0030   20 LIDPNIIRRIVDAAGITPGDTVLEIGPGLG--ALtrALLERAA--RVTAVEIDRRLAAILRETFAAY---PNLTVIEGDA 92


                 ..
gi 505177842 111 LE 112
Cdd:COG0030   93 LK 94
ksgA PRK14896
16S ribosomal RNA methyltransferase A;
34-117 2.67e-03

16S ribosomal RNA methyltransferase A;


Pssm-ID: 237852 [Multi-domain]  Cd Length: 258  Bit Score: 37.57  E-value: 2.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  34 VDRNTLEMIKQIIRINHTTRILEIGTAIGYSAMQFASVSDdiQVTTIERNSEMIHQAKSNISNnhySHRIRLIEGDALE- 112
Cdd:PRK14896  13 IDDRVVDRIVEYAEDTDGDPVLEIGPGKGALTDELAKRAK--KVYAIELDPRLAEFLRDDEIA---AGNVEIIEGDALKv 87


                 ....*...
gi 505177842 113 ---QFDKI 117
Cdd:PRK14896  88 dlpEFNKV 95
COG4262 COG4262
Predicted spermidine synthase with an N-terminal membrane domain [General function prediction ...
 52-153 2.87e-03

Predicted spermidine synthase with an N-terminal membrane domain [General function prediction only];


Pssm-ID: 443404 [Multi-domain]  Cd Length: 426  Bit Score: 37.92  E-value: 2.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  52 TRILEIGTAIGYSAMQFASVSDDIQVTTIERNSEMIHQAKSNIS----NNH--YSHRIRLIEGDA---LEQfdkiKDQTF 122
Cdd:COG4262  288 RRVLVLGGGDGLAAREVLKYPDVESVTLVDLDPEVTDLAKTNPFlrelNGGalNDPRVTVVNADAfqfLRE----TDEKY 363

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 505177842 123 DMLFIDA--------AKAQSKKFFELYTPLLREGGIVIT 153
Cdd:COG4262  364 DVIIVDLpdpsnfslGKLYSVEFYRLVRRHLAPGGVLVV 402
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 53-95 4.43e-03

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 36.92  E-value: 4.43e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 505177842  53 RILEIGTAIGYSAMQFAS-VSDDIQVTTIERNSEMIHQAKSNIS 95
Cdd:PRK13942  79 KVLEIGTGSGYHAAVVAEiVGKSGKVVTIERIPELAEKAKKTLK 122
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 53-123 4.60e-03

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 37.05  E-value: 4.60e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505177842  53 RILEI--GTaiGYSAMQFA-SVSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALE-QFDkikDQTFD 123
Cdd:PRK00216  54 KVLDLacGT--GDLAIALAkAVGKTGEVVGLDFSEGMLAVGREKLRDLGLSGNVEFVQGDAEAlPFP---DNSFD 123
Trm5 COG2520
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ...
 76-164 5.15e-03

tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442010 [Multi-domain]  Cd Length: 333  Bit Score: 37.15  E-value: 5.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842  76 QVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEqFDKIKDQTFD---M-LFIDAakaqsKKFFELYTPLLREGGIV 151
Cdd:COG2520  205 KVVAIDINPDAVEYLKENIRLNKVEDRVTPILGDARE-VAPELEGKADriiMnLPHSA-----DEFLDAALRALKPGGVI 278

                         90
                 ....*....|...
gi 505177842 152 ItdnvlYHGFVSD 164
Cdd:COG2520  279 H-----YYEIVPE 286
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 55-152 5.70e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 34.95  E-value: 5.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   55 LEIGTAIGYSAMQFASVSddIQVTTIERNSEMIHQAKSNISNNHYShrirLIEGDALE-QFdkiKDQTFD----MLFIDA 129
Cdd:pfam08241   1 LDVGCGTGLLTELLARLG--ARVTGVDISPEMLELAREKAPREGLT----FVVGDAEDlPF---PDNSFDlvlsSEVLHH 71

                          90       100
                  ....*....|....*....|...
gi 505177842  130 AKAQSKKFFELYTpLLREGGIVI 152
Cdd:pfam08241  72 VEDPERALREIAR-VLKPGGILI 93
Met_10 pfam02475
Met-10+ like-protein; The methionine-10 mutant allele of N. crassa codes for a protein of ...
 61-151 5.83e-03

Met-10+ like-protein; The methionine-10 mutant allele of N. crassa codes for a protein of unknown function, Swiss:O27901. However, homologous proteins have been found in yeast suggesting this protein may be involved in methionine biosynthesis, transport and/or utilization.


Pssm-ID: 396850 [Multi-domain]  Cd Length: 198  Bit Score: 36.56  E-value: 5.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505177842   61 IGYSAMQFASVSDDIQVTTIERNSEMIHQAKSNISNNHYSHRIRLIEGDALEQFDKIKDQTFDMLFIDAAkaqsKKFFEL 140
Cdd:pfam02475 110 IGPFSIPIAKHSKARRVYAIELNPESYKYLKENIKLNKVEDVVKPILGDVREVILEDVADRVVMNLPGSA----HEFLDK 185

                          90
                  ....*....|.
gi 505177842  141 YTPLLREGGIV 151
Cdd:pfam02475 186 AFAAVRDGGVI 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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