|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
64-723 |
8.83e-169 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 501.76 E-value: 8.83e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 64 TERDKTPLQIFDRNGTLIGEMKRAGQREIRADNLKQHeaIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGG 142
Cdd:COG0744 49 DLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPH--LKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGvVQGG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 143 STITQQLAK-LILSevetaeqgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASW 221
Cdd:COG0744 127 STITQQLVKnLFLS-----------------NERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQ 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 222 RYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEHPYVVQQsrrvDVERMLREfreehsvleks 301
Cdd:COG0744 190 YYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQA----EADAAKAE----------- 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 302 agekilyssKIGKYYYARNFKLNRAPDFLNEVEKFLHRNYTTDDLKTRVLRVDTTLDVRTQEPAAQLLGNRVAEIRKtlq 381
Cdd:COG0744 255 ---------PLTLVPPPNGAAAGKYPYFVDYVRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEGKP--- 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 382 kekqqllaknnkagaetvqlieDGINGSYVGLNPENGYIESLVGGYEYKSSSpINRAFSIYRQPGSTIKALVYALAMQEK 461
Cdd:COG0744 323 ----------------------GGLQAALVVVDPKTGEVLAMVGGRDYGKSQ-FNRATQAKRQPGSTFKPFVYAAALEQG 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 462 IiNPSTIVEDKAIKI--GGYSPKNWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFTDtMARAAGLTEAemaqrvgD 539
Cdd:COG0744 380 Y-TPATTVDDEPVTFpgGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVD-TARRLGITSP-------L 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 540 RKNLAMALGAIELSPIELARIYATIASGGYAVEPVMILKVTDFDGNAIYTADQTkpRERLLDPVACAMVLNLMQAVIsSE 619
Cdd:COG0744 451 DPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPK--CEQVISPEVAYLMTDMLQDVV-TS 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 620 GTMpiTAKEVSGI-AGGKTGTVQSpsaakakwnnrsgIRDTWFVGALPQQISVIWVGHERGAPFAG-SGSGTAGAVWKDF 697
Cdd:COG0744 528 GTG--RAARLPGRpVAGKTGTTND-------------NRDAWFVGYTPQLVTAVWVGNDDNSPMGYvTGGSLPAPIWRDF 592
|
650 660
....*....|....*....|....*.
gi 504615179 698 SKQYVQLHPeNRQFLPPleSGFVKLD 723
Cdd:COG0744 593 MEAALEGLP-VEDFPKP--SGVVRID 615
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
106-703 |
3.16e-124 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 383.53 E-value: 3.16e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 106 ALLASEDRNFYHHGGVQFKSIARALFASLRSGDV-QGGSTITQQLAKLILSEVEtaeqgksqndttkirkRSIFNKLSEF 184
Cdd:TIGR02074 17 AFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVlEGGSTITQQLAKNLYLTNE----------------RTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 185 YCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKL 264
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 265 VLKLMAEHPYVVQQSRrvdvermlrefreehsvlEKSAGEKILYSSkigkyyYARNFKLNRAPDFLNEVEKFLHRNYtTD 344
Cdd:TIGR02074 161 VLSNMVENGYITAEEA------------------EEAINEPIQLYL------QTKKSEQYKAPYFVDYVIQELEEEY-GE 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 345 DLKTRVLRVDTTLDVRTQEPAAQLLgnrvaeirktlqkekQQLLAKNNKAGAETVQliedginGSYVGLNPENGYIESLV 424
Cdd:TIGR02074 216 ELYTGGLKIYTTLDLDAQKAAEKVL---------------NTGLRVAGRRDGDDLQ-------AALVAIDPDTGAVRALV 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 425 GGYEYKSSSpINRAFSIYRQPGSTIKALVYALAMqEKIINPSTIVEDKAIKIGG---YSPKNWYKGYKGKVTARQAFALS 501
Cdd:TIGR02074 274 GGRDYGKSQ-FNRATQAKRQPGSTFKPFVYAAAL-EKGLTPATIVNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQS 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 502 MNTIPVTLLQEIGMSKFTDTmARAAGLTeaemaqrVGDRKNLAMALGAIELSPIELARIYATIASGGYAVEPVMILKVTD 581
Cdd:TIGR02074 352 RNIPAVRLLQEVGLDKVVAL-AKRFGIT-------SPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVD 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 582 FDGNAIYTADQTKprERLLDPVACAMVLNLMQAVISSeGTMPiTAKEVSGIAGGKTGTVQspsaakakwNNrsgiRDTWF 661
Cdd:TIGR02074 424 RDGKVIYENKPKT--TQVISPATAYIMTDMLKGVVES-GTGR-SARLPGRPVAGKTGTTQ---------NW----RDAWF 486
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 504615179 662 VGALPQQISVIWVGHERGAPF--AGSGSGTAGAVWKDFSKQYVQ 703
Cdd:TIGR02074 487 VGYTPYYVTAVWVGYDDKKTLgkSGTGGGLAAPIWRDFMAEALK 530
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
101-728 |
4.10e-63 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 226.27 E-value: 4.10e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 101 EAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSG-DVQGGSTITQQLAK-LILSEVetaeqgksqndttkirkRSIF 178
Cdd:PRK14850 167 EMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGhTIQGGSTLTQQLVKnLFLTNT-----------------RSLW 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 179 NKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLS----VGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAAS 254
Cdd:PRK14850 230 RKINEIYMALILDRFYSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTN 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 255 MQRALARQKLVLKLMAEHPYvvqqsrrvdVERMLREFREEHSVLEKSAGEKILYSskigkyyyarnfklnraPDFLNEVE 334
Cdd:PRK14850 310 PNLTLKRRNLVLFLLYKQKV---------ITRKLYKDLCSRPLNVQSKGNIISSH-----------------PAFIQLVC 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 335 KFLHR--NYTTDDLKTrvLRVDTTLDVRTQEPAAQllgnrvaEIRKTLQKEKQQLLAKNnkagaetvqliedgINGSYVG 412
Cdd:PRK14850 364 EEFHKkiHYPFKNFSG--TKIFTTLDYISQNAAEQ-------AVKIGIPILKRKKRLKD--------------LEVAMVI 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 413 LNPENGYIESLVGgyeykSSSP----INRAFSIYRQPGSTIKALVYALAM-QEKIINPSTIVEDKAIKI----GGY-SPK 482
Cdd:PRK14850 421 IDRFSGEVRALIG-----SSKPefngYNRALKARRSIGSLSKPITYLTALsQPEKYHLNTWISDTPISIkldnGQYwTPK 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 483 NWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFTDTMARaAGLTEAEMAqrvgdrKNLAMALGAIELSPIELARIYA 562
Cdd:PRK14850 496 NNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWIL-LGISSNYIT------PLPSISLGAINLTPMEVAQVFQ 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 563 TIASGGYAVEPVMILKVTDFDGNAIYtadQTKPR-ERLLDPVACAMVLNLMQAVISSEGTMPITAKEVSGIAGGKTGTVq 641
Cdd:PRK14850 569 IIGSGGYKSSLSSIRSIISDDNKVLY---QNFPQsKHVESSQASYLTLYAMQQVVKSGTAKSLGTIFKEFSLAGKTGTT- 644
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 642 spsaakakwNNrsgIRDTWFVGALPQQISVIWVGHERGAPFAGSGSGTAGAVWkdfsKQYVQLH-PENRQFLPPLESGFV 720
Cdd:PRK14850 645 ---------NN---LVDSWFVGIDGKQVVITWIGRDNNHTTKLYGSSGAMKIY----KRYLQYQnPVPLVLKAPNNINMF 708
|
....*...
gi 504615179 721 KLDICGEL 728
Cdd:PRK14850 709 YINNLGEL 716
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
77-270 |
1.04e-60 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 202.75 E-value: 1.04e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 77 NGTLIGEMKRAGQREIRADNLKqhEAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGGSTITQQLAKLILS 155
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIP--PALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRiVQGGSTITQQLAKNLFL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 156 EVEtaeqgksqndttkirkRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARNLSLAE 235
Cdd:pfam00912 79 TPE----------------RTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAE 142
|
170 180 190
....*....|....*....|....*....|....*
gi 504615179 236 AAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMA 270
Cdd:pfam00912 143 AALLAGLPQAPSRYNPLRNPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
64-723 |
8.83e-169 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 501.76 E-value: 8.83e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 64 TERDKTPLQIFDRNGTLIGEMKRAGQREIRADNLKQHeaIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGG 142
Cdd:COG0744 49 DLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPH--LKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGvVQGG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 143 STITQQLAK-LILSevetaeqgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASW 221
Cdd:COG0744 127 STITQQLVKnLFLS-----------------NERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQ 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 222 RYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEHPYVVQQsrrvDVERMLREfreehsvleks 301
Cdd:COG0744 190 YYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQA----EADAAKAE----------- 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 302 agekilyssKIGKYYYARNFKLNRAPDFLNEVEKFLHRNYTTDDLKTRVLRVDTTLDVRTQEPAAQLLGNRVAEIRKtlq 381
Cdd:COG0744 255 ---------PLTLVPPPNGAAAGKYPYFVDYVRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEGKP--- 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 382 kekqqllaknnkagaetvqlieDGINGSYVGLNPENGYIESLVGGYEYKSSSpINRAFSIYRQPGSTIKALVYALAMQEK 461
Cdd:COG0744 323 ----------------------GGLQAALVVVDPKTGEVLAMVGGRDYGKSQ-FNRATQAKRQPGSTFKPFVYAAALEQG 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 462 IiNPSTIVEDKAIKI--GGYSPKNWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFTDtMARAAGLTEAemaqrvgD 539
Cdd:COG0744 380 Y-TPATTVDDEPVTFpgGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVD-TARRLGITSP-------L 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 540 RKNLAMALGAIELSPIELARIYATIASGGYAVEPVMILKVTDFDGNAIYTADQTkpRERLLDPVACAMVLNLMQAVIsSE 619
Cdd:COG0744 451 DPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPK--CEQVISPEVAYLMTDMLQDVV-TS 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 620 GTMpiTAKEVSGI-AGGKTGTVQSpsaakakwnnrsgIRDTWFVGALPQQISVIWVGHERGAPFAG-SGSGTAGAVWKDF 697
Cdd:COG0744 528 GTG--RAARLPGRpVAGKTGTTND-------------NRDAWFVGYTPQLVTAVWVGNDDNSPMGYvTGGSLPAPIWRDF 592
|
650 660
....*....|....*....|....*.
gi 504615179 698 SKQYVQLHPeNRQFLPPleSGFVKLD 723
Cdd:COG0744 593 MEAALEGLP-VEDFPKP--SGVVRID 615
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
68-737 |
5.48e-132 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 411.86 E-value: 5.48e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 68 KTPLQIFDRNGTLIGEMKRagQR----EIRA--DNLKQheaivwALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQ 140
Cdd:COG5009 45 PTPSRVYSADGKLIAEFGE--ERripvPIEEipPLLIN------AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRrVQ 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 141 GGSTITQQLAK-LILSevetaeqgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDA 219
Cdd:COG5009 117 GGSTITQQVAKnFLLS-----------------PERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAYGVAAA 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 220 SWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEHPYVVQqsrrvdvermlrefrEEHsvlE 299
Cdd:COG5009 180 AQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQ---------------AEY---E 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 300 KSAGEKIlysskigKYYYARNFKLNRAPDFLNEVEKFLHRNYTTDDLKTRVLRVDTTLDVRTQEPAAQLL---------- 369
Cdd:COG5009 242 AAKAEPL-------TARYHGASAEVDAPYFAEMVRRELVERYGEDALYTGGLKVYTTLDPRLQEAAEKALrdgllaydrr 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 370 -GNRVAEIRKTLQKEK-QQLLAK---------------------------------------------NNKAGAET---- 398
Cdd:COG5009 315 hGYRGPEAHLDLAEEDwDEALAEvpdvgdlrpavvlevddksarvglrdgetgtlpleglkwarpyinDNRRGPAPksas 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 399 ----------VQLIEDG---------INGSYVGLNPENGYIESLVGGYEYKSSSpINRAFSIYRQPGSTIKALVYALAMq 459
Cdd:COG5009 395 dvlkpgdvirVRPVADGgwrlrqipeVQGALVALDPHTGAVLALVGGFDFEQSK-FNRATQAKRQPGSSFKPFVYAAAL- 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 460 EKIINPSTIVEDKAIKI------GGYSPKNWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFtdtmaraaglteAEM 533
Cdd:COG5009 473 DNGYTPATIINDAPIVFddggggGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYV------------IDY 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 534 AQRVG--DR--KNLAMALGAIELSPIELARIYATIASGGYAVEPVMILKVTDFDGNAIYTAD------------------ 591
Cdd:COG5009 541 AERFGiySKlpPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADparacedcdaaewdgaep 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 592 -QTKPRERLLDPVACAMVLNLMQAVIsSEGtmpiTAKEVSGI---AGGKTGTVQSPsaakakwnnrsgiRDTWFVGALPQ 667
Cdd:COG5009 621 rLPDPAEQVIDPRTAYQMTSMLRGVV-QRG----TGRRARALgrdIAGKTGTTNDS-------------KDAWFVGFTPD 682
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504615179 668 QISVIWVGHERGAPF--AGSGSGTAGAVWKDFSKQYVQLHPEnRQFLPPleSGFVKLDICGELGLILKPEYP 737
Cdd:COG5009 683 LVAGVWVGFDDPRSLgrGETGGRAALPIWIDFMKAALKDKPE-KPFPVP--EGIVTVRIDPKTGLLASPGDP 751
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
106-703 |
3.16e-124 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 383.53 E-value: 3.16e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 106 ALLASEDRNFYHHGGVQFKSIARALFASLRSGDV-QGGSTITQQLAKLILSEVEtaeqgksqndttkirkRSIFNKLSEF 184
Cdd:TIGR02074 17 AFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVlEGGSTITQQLAKNLYLTNE----------------RTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 185 YCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKL 264
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 265 VLKLMAEHPYVVQQSRrvdvermlrefreehsvlEKSAGEKILYSSkigkyyYARNFKLNRAPDFLNEVEKFLHRNYtTD 344
Cdd:TIGR02074 161 VLSNMVENGYITAEEA------------------EEAINEPIQLYL------QTKKSEQYKAPYFVDYVIQELEEEY-GE 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 345 DLKTRVLRVDTTLDVRTQEPAAQLLgnrvaeirktlqkekQQLLAKNNKAGAETVQliedginGSYVGLNPENGYIESLV 424
Cdd:TIGR02074 216 ELYTGGLKIYTTLDLDAQKAAEKVL---------------NTGLRVAGRRDGDDLQ-------AALVAIDPDTGAVRALV 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 425 GGYEYKSSSpINRAFSIYRQPGSTIKALVYALAMqEKIINPSTIVEDKAIKIGG---YSPKNWYKGYKGKVTARQAFALS 501
Cdd:TIGR02074 274 GGRDYGKSQ-FNRATQAKRQPGSTFKPFVYAAAL-EKGLTPATIVNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQS 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 502 MNTIPVTLLQEIGMSKFTDTmARAAGLTeaemaqrVGDRKNLAMALGAIELSPIELARIYATIASGGYAVEPVMILKVTD 581
Cdd:TIGR02074 352 RNIPAVRLLQEVGLDKVVAL-AKRFGIT-------SPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVD 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 582 FDGNAIYTADQTKprERLLDPVACAMVLNLMQAVISSeGTMPiTAKEVSGIAGGKTGTVQspsaakakwNNrsgiRDTWF 661
Cdd:TIGR02074 424 RDGKVIYENKPKT--TQVISPATAYIMTDMLKGVVES-GTGR-SARLPGRPVAGKTGTTQ---------NW----RDAWF 486
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 504615179 662 VGALPQQISVIWVGHERGAPF--AGSGSGTAGAVWKDFSKQYVQ 703
Cdd:TIGR02074 487 VGYTPYYVTAVWVGYDDKKTLgkSGTGGGLAAPIWRDFMAEALK 530
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
80-714 |
7.74e-92 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 304.34 E-value: 7.74e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 80 LIGEMKRAGQREIRADNLKQH-EAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGGSTITQQLAK-LILSe 156
Cdd:TIGR02071 135 LIAMLYSPNGEQRLFVPRDQFpELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRtVQGGSTLTQQLVKnLFLS- 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 157 vetaeqgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSV----GFEDASWRYFGRAARNLS 232
Cdd:TIGR02071 214 ----------------NERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGQSGDdaihGFPLASQYYFGRPLGELS 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 233 LAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEHPYVVQQSRRVDVERMLRefreehsvLEKSAGekilysski 312
Cdd:TIGR02071 278 LDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLG--------VQKKGG--------- 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 313 gkyyyarnfKLNRAPDFLNEVEKFLHRNYTTDDLKTRVLRVDTTLDVRTQEPAAQLLGNRVAEIRKTlqkekqqllaKNN 392
Cdd:TIGR02071 341 ---------IISRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPALKKK----------KKL 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 393 KAgaetvqliedgINGSYVGLNPENGYIESLVGGYEYKSSSpINRAFSIYRQPGSTIKALVYALAM-QEKIINPSTIVED 471
Cdd:TIGR02071 402 PD-----------LEAAMVVTDRFTGEVRAMVGGSDPQFAG-FNRALQARRQIGSLVKPAVYLTALsQPDKYRLNTWIED 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 472 KAIKIGG-----YSPKNWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFTDTMARAAGLteaemaqRVGDRKNLAMA 546
Cdd:TIGR02071 470 QPLSIKLsngqvWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGIN-------KDEIPPVPSML 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 547 LGAIELSPIELARIYATIASGGYAVEPVMILKVTDFDGNAIYTADQTKprERLLDPVACAMVLNLMQAVISSEgtmpiTA 626
Cdd:TIGR02071 543 LGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQA--EQAVPSQAAYLTLYAMQQVVQRG-----TA 615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 627 KEVSGIAG-----GKTGTVqspsaakakwNNrsgIRDTWFVGALPQQISVIWVGHERGAPFAGSGSGTAGAVWKDFSKqy 701
Cdd:TIGR02071 616 RSLGADFPslslaGKTGTT----------ND---NRDSWFAGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLS-- 680
|
650
....*....|...
gi 504615179 702 vQLHPENRQFLPP 714
Cdd:TIGR02071 681 -YQTPEPLLLVPP 692
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
72-734 |
2.19e-89 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 298.67 E-value: 2.19e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 72 QIFDRNGTLIgemkRA-----GQREIRADnLKQ-HEAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGGST 144
Cdd:COG4953 45 VVLDRDGTLL----RAflaadGQWRLPVP-LDEvSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRiVSGGST 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 145 ITQQLAKLIlsevetaEQgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYF 224
Cdd:COG4953 120 LTMQVARLL-------EP----------RPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYF 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 225 GRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEHPYVVQQsrrvDVERMLREfreehsvleksage 304
Cdd:COG4953 183 GKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVIDAE----EAALALLE-------------- 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 305 kilyssKIGKYYYARNFklnRAPDFLNEvekfLHRNYTTDDlktrvlRVDTTLDVRTQEPAAQLLGNRVAEIRktlQKEK 384
Cdd:COG4953 245 ------PVPARRRPLPQ---LAPHLARR----LLRQLPGGT------RIRTTLDAGLQRRLERLVRRYVRRLK---QNGI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 385 QQL--LAKNNKAGAetvqlIEdgingSYVG----LNPEN-GYIeslvggyeyksssPINRAfsiYRQPGSTIKALVYALA 457
Cdd:COG4953 303 HNAavLVVDNRTGE-----VL-----AYVGsadfFDASRqGQV-------------DMVRA---LRSPGSTLKPFLYGLA 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 458 MQEKIINPSTIVEDKAIKIGGYSPKNWYKGYKGKVTARQAFALSMNtIP-VTLLQEIGMSKFTDTMaRAAGLTeaeMAQR 536
Cdd:COG4953 357 LDQGLIHPETLLADVPTSFGGYRPENFDGTFQGPVSAREALARSLN-IPaVRLLEALGPARFYARL-RRAGLR---LLLP 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 537 VGDRKNLAMALGAIELSPIELARIYATIASGGYAVEPVmilkvtdfdgnaiYTADQTKPRE-RLLDPVACAMVLNLMqav 615
Cdd:COG4953 432 PAEHYGLSLILGGAEVTLEELVGLYAALARGGEARPLR-------------LLAGEPASPGrRLLSPGAAWLVRDIL--- 495
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 616 isSEGTMPITAKEVSGIAGG-----KTGTvqSpsaakakwnnrSGIRDTWFVGALPQQISVIWVGHERGAPFAG-SGSGT 689
Cdd:COG4953 496 --SDVPRPDGAFGWRALDSPppiawKTGT--S-----------YGFRDAWAVGFTGRYTVGVWVGNPDGTPVPGlTGAEA 560
|
650 660 670 680
....*....|....*....|....*....|....*....|....*
gi 504615179 690 AGAVWKDFskqYVQLHPENRQFLPPLESGFVKLDICGELGLILKP 734
Cdd:COG4953 561 AAPLLFDI---FDLLPASRWPLPFPPPAGLLRVEVCAPSGLLAGP 602
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
73-729 |
2.67e-79 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 270.45 E-value: 2.67e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 73 IFDRNGTLIGEMKRA-GQREIRADNLKQHEAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGGSTITQQLA 150
Cdd:TIGR02073 14 VLDRHGTLLRALLANdGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRrVSGGSTLTMQLA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 151 KLILSEvetaeqgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARN 230
Cdd:TIGR02073 94 RLLDPE----------------LSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 231 LSLAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEhPYVVQQSrrvdverMLREFREEHSVLEKSAGEKIlyss 310
Cdd:TIGR02073 158 LSLAEAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVE-QGPDDSE-------QVALAALEPLPALPEPLPQL---- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 311 kigkyyyarnfklnrAPDFlneVEKFLHRNyttddlKTRVLRVDTTLDvrtqepaaqllgnrvaeirKTLQKeKQQLLAK 390
Cdd:TIGR02073 226 ---------------APHF---ALKLLRAR------PEIASVIVSTLD-------------------ADLQR-RLEELAR 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 391 NNKAGaetvQLIEDGINGSYVGLNPENGYIESLVGGYEYKSSSpinRAFSI-----YRQPGSTIKALVYALAMQEKIINP 465
Cdd:TIGR02073 262 RYLSA----LRPRGISNLAILVVDNRSGAVLAYVGSADFFDDS---NSGQVdgvraPRSPGSTLKPFLYALALDDGLLHP 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 466 STIVEDKAIKIGGYSPKNWYKGYKGKVTARQAFALSMNtIP-VTLLQEIGMSKFTDTMaRAAGLTEAEMAQRVGdrkNLA 544
Cdd:TIGR02073 335 DSLLKDVPLRFGDYAPENFDKTFHGPVPAREALARSLN-IPaVRLLERVGPPRFADFL-RQAGLNLLKPKSDYY---GLS 409
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 545 MALGAIELSPIELARIYATIASGGYAVEPVMILkvtdfdgnaiyTADQTKPRERLLDPVACAMVLNLMQAVISSEGTMPI 624
Cdd:TIGR02073 410 LALGGAEITLQDLANLYAMLANQGLSGPLRFLQ-----------TDAKRPERERLLSPGAAWIVLDILKDRPRPDDTLPL 478
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 625 TAKEVSGIAGGKTGTVQspsaakakwnnrsGIRDTWFVGALPQQISVIWVGHERGAPFAG-SGSGTAGAVWKDFskqyVQ 703
Cdd:TIGR02073 479 SALPTRLPLAWKTGTSY-------------GFRDAWAAGVSGRYTIGVWVGNFDGKPNPGfFGAAAAAPLLFDI----LD 541
|
650 660
....*....|....*....|....*.
gi 504615179 704 LHPENRQFLPPLESgfVKLDICGELG 729
Cdd:TIGR02073 542 ALQASEASTLPRPL--KEVPGCLVLG 565
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
101-728 |
4.10e-63 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 226.27 E-value: 4.10e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 101 EAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSG-DVQGGSTITQQLAK-LILSEVetaeqgksqndttkirkRSIF 178
Cdd:PRK14850 167 EMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGhTIQGGSTLTQQLVKnLFLTNT-----------------RSLW 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 179 NKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLS----VGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAAS 254
Cdd:PRK14850 230 RKINEIYMALILDRFYSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTN 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 255 MQRALARQKLVLKLMAEHPYvvqqsrrvdVERMLREFREEHSVLEKSAGEKILYSskigkyyyarnfklnraPDFLNEVE 334
Cdd:PRK14850 310 PNLTLKRRNLVLFLLYKQKV---------ITRKLYKDLCSRPLNVQSKGNIISSH-----------------PAFIQLVC 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 335 KFLHR--NYTTDDLKTrvLRVDTTLDVRTQEPAAQllgnrvaEIRKTLQKEKQQLLAKNnkagaetvqliedgINGSYVG 412
Cdd:PRK14850 364 EEFHKkiHYPFKNFSG--TKIFTTLDYISQNAAEQ-------AVKIGIPILKRKKRLKD--------------LEVAMVI 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 413 LNPENGYIESLVGgyeykSSSP----INRAFSIYRQPGSTIKALVYALAM-QEKIINPSTIVEDKAIKI----GGY-SPK 482
Cdd:PRK14850 421 IDRFSGEVRALIG-----SSKPefngYNRALKARRSIGSLSKPITYLTALsQPEKYHLNTWISDTPISIkldnGQYwTPK 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 483 NWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFTDTMARaAGLTEAEMAqrvgdrKNLAMALGAIELSPIELARIYA 562
Cdd:PRK14850 496 NNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWIL-LGISSNYIT------PLPSISLGAINLTPMEVAQVFQ 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 563 TIASGGYAVEPVMILKVTDFDGNAIYtadQTKPR-ERLLDPVACAMVLNLMQAVISSEGTMPITAKEVSGIAGGKTGTVq 641
Cdd:PRK14850 569 IIGSGGYKSSLSSIRSIISDDNKVLY---QNFPQsKHVESSQASYLTLYAMQQVVKSGTAKSLGTIFKEFSLAGKTGTT- 644
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 642 spsaakakwNNrsgIRDTWFVGALPQQISVIWVGHERGAPFAGSGSGTAGAVWkdfsKQYVQLH-PENRQFLPPLESGFV 720
Cdd:PRK14850 645 ---------NN---LVDSWFVGIDGKQVVITWIGRDNNHTTKLYGSSGAMKIY----KRYLQYQnPVPLVLKAPNNINMF 708
|
....*...
gi 504615179 721 KLDICGEL 728
Cdd:PRK14850 709 YINNLGEL 716
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
103-695 |
4.98e-63 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 226.96 E-value: 4.98e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 103 IVWALLASEDRNFYHHGGVQFKSIARALFASLRSG-DVQGGSTITQQLAK-LILSEvetaeqgksqndttkirKRSIFNK 180
Cdd:PRK09506 223 LVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGrTVQGGSTLTQQLVKnLFLSN-----------------ERSLWRK 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 181 LSEFYCTWFLESKYDKPTILAIYLNKVYLGMLS----VGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQ 256
Cdd:PRK09506 286 ANEAYMALIMDARYSKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPK 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 257 RALARQKLVLKLMaehpyvvQQSRRVDVErmLREFREEHSVLEKSAGEKIlysskigkyyyarnfklNRAPDFLNEVEKF 336
Cdd:PRK09506 366 LALERRNLVLRLL-------QQQQIIDQE--LYDMLSARPLGVQPKGGVI-----------------SPQPAFMQMVRQE 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 337 LHRNY--TTDDLKTrvLRVDTTLDVRTQEPAAQLLGNRVAEIRKTlqkekqqllakNNKAGAETVQLIEDGINGSyvgln 414
Cdd:PRK09506 420 LQAKLgdKVKDLSG--VKIFTTLDPVSQDAAEKAVEEGIPALKKQ-----------RKLSDLETAMVVVDRFSGE----- 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 415 pengyIESLVGGYEYKSSSpINRAFSIYRQPGSTIKALVYALAM-QEKIINPSTIVEDKAIKI---GG--YSPKNWYKGY 488
Cdd:PRK09506 482 -----VRAMVGGSEPQFAG-YNRAMQARRSIGSLAKPATYLTALsQPDKYRLNTWIADAPISLrqpNGqvWSPQNDDRRF 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 489 KGKVTARQAFALSMNTIPVTLLQEIGMSKFTDTMaraaglteaemaQRVGDRKNL-----AMALGAIELSPIELARIYAT 563
Cdd:PRK09506 556 SGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTW------------IKLGVPKDQlnpvpAMLLGALNLTPIEVAQAFQT 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 564 IASGGYAVEPVMILKVTDFDGNAIYtadQTKPR-ERLLDPVACAMVLNLMQAVISSEGTMPITAKEVSGIAGGKTGTVqs 642
Cdd:PRK09506 624 IASGGNRAPLSALRSVIAEDGKVLY---QSFPQaERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGTT-- 698
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 504615179 643 psaakakwNNrsgIRDTWFVGALPQQISVIWVGHERGAPFAGSGSGTAGAVWK 695
Cdd:PRK09506 699 --------ND---LVDSWFAGIDGKEVTITWVGRDNNQPTKLYGASGAMTIYQ 740
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
77-270 |
1.04e-60 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 202.75 E-value: 1.04e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 77 NGTLIGEMKRAGQREIRADNLKqhEAIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGGSTITQQLAKLILS 155
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIP--PALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRiVQGGSTITQQLAKNLFL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 156 EVEtaeqgksqndttkirkRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARNLSLAE 235
Cdd:pfam00912 79 TPE----------------RTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAE 142
|
170 180 190
....*....|....*....|....*....|....*
gi 504615179 236 AAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMA 270
Cdd:pfam00912 143 AALLAGLPQAPSRYNPLRNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
55-605 |
4.04e-50 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 189.57 E-value: 4.04e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 55 IEAELKGELTERD---KTPLQIFDRNGTLI---GEMKRAGQReiradnLKQHEAI-VWALLASEDRNFYHHGGVQFKSIA 127
Cdd:PRK11636 29 IEPQLPDVATLKDvrlQTPMQVYSADGELIaqyGEKRRIPLT------LDQIPPEmVKAFIATEDSRFYEHHGVDPVGIF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 128 RALFASLRSGDV-QGGSTITQQLAK-LILSevetaeqgksqndttkiRKRSIFNKLSEFYCTWFLESKYDKPTILAIYLN 205
Cdd:PRK11636 103 RAASVALFSGHAsQGASTITQQLARnFFLS-----------------PERTLMRKIKEAFLAIRIEQLLTKDEILELYLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 206 KVYLGMLSVGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRALARQKLVLKLMAEHPYVVQQSrrvdve 285
Cdd:PRK11636 166 KIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQ------ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 286 rmLREFREEHSVLEKSAGEkILYSskigkyyyarnfklnrAPdFLNE-VEKFLHRNYtTDDLKTRVLRVDTTLDVRTQEP 364
Cdd:PRK11636 240 --YDQARSEPIVANYHAPE-IAFS----------------AP-YLSEmVRQEMYNRY-GENAYEDGYRVYTTITRKVQQA 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 365 AAQLLGNRV--------------------------AEIRKTLQK------------------EKQQLLAKNNK------- 393
Cdd:PRK11636 299 AQQAVRNNVldydmrhgyrgpanvlwkvgesawdnKKITDTLKAlptygpllpavvtsanpqEATAMLADGSSvalpmeg 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 394 -------------------------AGAET-VQLIEDG--------INGSYVGLNPENGYIESLVGGYEYkSSSPINRAF 439
Cdd:PRK11636 379 vrwarpyrsdtqqgptprkvtdvvqTGQQIwVRQVDDAwwlaqvpdVNSALVSINPQNGAVMALVGGFDF-NQSKFNRAT 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 440 SIYRQPGSTIKALVYALAMqEKIINPSTIVEDKAIK---IGG---YSPKNWYKGYKGKVTARQAFALSMNTIPVTLLqei 513
Cdd:PRK11636 458 QALRQVGSNIKPFLYTAAM-DKGLTLASMLNDVPISrwdAGAgsdWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAM--- 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 514 gmskftdtmaRAAGLT-EAEMAQRVG-DRKNL----AMALGAIELSPIELARIYATIASGGYAVEPVMILKVTDFDGNAI 587
Cdd:PRK11636 534 ----------RAMGVDyAAEYLQRFGfPAQNIvhteSLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVI 603
|
650
....*....|....*...
gi 504615179 588 YTAdqtKPRerlldpVAC 605
Cdd:PRK11636 604 FEA---KPK------VAC 612
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
106-693 |
2.04e-37 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 150.62 E-value: 2.04e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 106 ALLASEDRNFYHHGGVQFKSIARALFASLRSGDV-QGGSTITQQLAKLIlsevetaeqgksqnDTtkiRKRSIFNKLSEF 184
Cdd:PRK11240 77 ALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRViSGGSTLTMQVARLL--------------DP---HPRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 185 YCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYNPAASMQRA-LARQK 263
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAeAARNK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 264 lVLKLMAEhpYVVQQSRRVDvermlrEFREEHSVLeksagekilysskigkyyyarnfklnrAPDFLNEVEKFLHRNYTT 343
Cdd:PRK11240 220 -VLERMAE--QGVWSAEQVK------ESREEPVWL---------------------------APRQMPQLAPLFARMMLG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 344 ddlKTRVLRVDTTLDVRTQEPAAQLLGNRvaeirktlqkeKQQLLAKNNKAgaetvQLIEDGINGS---YVG---LNPEN 417
Cdd:PRK11240 264 ---KSKSDKIVTTLDAGLQRRLEDLALNW-----------KGRLPPRSSLA-----MIVVDHTDMAvrgWVGsvdLNDDS 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 418 --GYIESLvggyeykssspinrafSIYRQPGSTIKALVYALAMQEKIINPSTIVEDKAIKIGGYSPKNWYKGYKGKVTAR 495
Cdd:PRK11240 325 rfGHVDMV----------------NAIRSPGSVLKPFVYGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 496 QAFALSMNTIPVTLLQEIGMSKFTDTMaRAAGLteaEMAQRVGDRKNLAMALGAIELSPIELARIYATIASGGYAVEpvm 575
Cdd:PRK11240 389 EALVRSLNLPAVQVLEAYGPKRFAAKL-RNVGL---PLYLPAGAEPNLSLILGGAGARLEDMVAAYSAFARHGKAAK--- 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 576 iLKVTdfdgnaiytaDQTKPRER-LLDPVACAMVLNLMqaviSSEGtMPITAKEVSGIA--GGKTGTvqspsaakakwnn 652
Cdd:PRK11240 462 -LRLQ----------PDDPLLERpLMSPGAAWIIRRIM----ADEA-QPLPDAALPRVVplAWKTGT------------- 512
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 504615179 653 RSGIRDTWFVGALPQQISVIWVGHERGAPFAGSgSGTAGAV 693
Cdd:PRK11240 513 SYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQ-FGFASAV 552
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
355-705 |
5.48e-34 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 138.03 E-value: 5.48e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 355 TTLDVRTQEPAAQLLGNRVAEirktlqkekqqllaKNNKAGAETVqliedgingsyvgLNPENGYIESLVG--------G 426
Cdd:COG0768 223 LTIDSDLQKIAEEALKKAVEE--------------YKAKSGAVVV-------------MDPKTGEILAMASypsfdpnlF 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 427 YEYKSSSPINRAFS-IYrQPGSTIKALVYALAMQEKIINPSTIVEDK-AIKIGGYSPKNWYKGYKGKVTARQAFALSMNT 504
Cdd:COG0768 276 VGGPDEPLRNRAVQgTY-EPGSTFKPFTAAAALEEGVITPDTTFDCPgYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNV 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 505 IPVTLLQEIGMSKFTDtMARAAGLTE-------AEMAQRVGDRKN------LAMALG-AIELSPIELARIYATIASGGYA 570
Cdd:COG0768 355 GFYKLALRLGIDKLYD-YLKKFGLGQktgidlpGEASGLLPSPKRwypgetATMSIGqGLSVTPLQLAQAYAAIANGGVL 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 571 VEPVMILKVTDFDGNAIYTadQTKPRERLLDPVACAMVLNLMQAVISSEGTmpiTAK--EVSGI-AGGKTGTVQSPSAAK 647
Cdd:COG0768 434 VKPHLVKEIVDPDGEVVKE--EPEVLRRVISPETAETVREGMEGVVNEPGG---TARraAIPGYrVAGKTGTAQVVDIGN 508
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504615179 648 AKwnNRSGIRDTWFVGALPQ---QISVIwVGHERGApFAGSGSGTAGAVWKDFSKQYVQLH 705
Cdd:COG0768 509 GG--YYKGRHIASFVGFAPAdnpRYAVA-VVVENPG-GGAYGGTVAAPVFREIMEAYLRLL 565
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
408-699 |
5.12e-30 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 120.60 E-value: 5.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 408 GSYVGLNPENGYIESLVGGYEY----KSSSPINRAFSIYRQPGSTIKALVYALAMQEKIINPSTIVEDKAIKIGGYSP-K 482
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYdpngFIGPLRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQGGKSiG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 483 NWYKGYKGKVTARQAFALSMNTIPVTLLQEIGMSKFTDTMARA-------AGLTEaEMAQRVGDRK---NLAMALGAIEL 552
Cdd:pfam00905 81 DWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFgygnktgIGLPG-ENAGYLTPYWlegATASFGIGLTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 553 SPIELARIYATIASGGYAVEPVMILKVTDfdgnaiyTADQTKPRERLLDPVACAMVLNLMQAVISSeGTMPITAKEVSGI 632
Cdd:pfam00905 160 TPLQQAQAYAAIANGGKLVPPHLVKSIED-------KVDPKVLNKLPISKSTAEKVKDMLRLVVND-GTGTGTAAVPGYK 231
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504615179 633 AGGKTGTVQspSAAKAKWNNRSGIRDTWFVGALPQQISVIWVGHERGAPFAGSGSGTAGAVWKDFSK 699
Cdd:pfam00905 232 VAGKTGTAQ--VAGPKGGGYYDGAQIGWFVGYAPADNPKYAFAVLIDDPKRYYGGKVAAPIFKDILE 296
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
95-270 |
7.17e-27 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 109.47 E-value: 7.17e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 95 DNLKQheaivwALLASEDRNFYHHGGVQFKSIARALFASLRSGD-VQGGSTITQQLAK-LILSEvetaeqgksqndttki 172
Cdd:TIGR02070 65 PNLKR------AVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKvVRGGSTISQQLAKnLFLWS---------------- 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 173 rKRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAARNLSLAEAAMLVGIVPAPSVYN-- 250
Cdd:TIGR02070 123 -GRSYLRKGLEAWATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDen 201
|
170 180
....*....|....*....|.
gi 504615179 251 -PAASMQRalaRQKLVLKLMA 270
Cdd:TIGR02070 202 rPGPYVRR---KATWILKQMG 219
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
92-275 |
2.61e-25 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 105.27 E-value: 2.61e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 92 IRADNLKQHeaIVWALLASEDRNFYHHGGVQFKSIARALFASLRSGDVQGGSTITQQLAKLILSEVEtaeqgksqndttk 171
Cdd:PRK13481 48 VSADNMPEY--VKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNE------------- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 172 irkRSIFNKLSEFYCTWFLESKYDKPTILAIYLNKVYLGMLSVGFEDASWRYFGRAAR-------NLSLAEAAMLVGIVP 244
Cdd:PRK13481 113 ---RSFTRKVKELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNknsttmsHITVLQSAILASKVN 189
|
170 180 190
....*....|....*....|....*....|.
gi 504615179 245 APSVYNPAASMQRALARQKLVLKLMAEHPYV 275
Cdd:PRK13481 190 APSVYNINDMSENFTQRVSTNLEKMKQQNYI 220
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
356-701 |
4.35e-24 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 107.61 E-value: 4.35e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 356 TLDVRTQEPAAQLLGNRvaeirktlqkekqqllaknnkagaetvqliedgiNGSYVGLNPENGYIESLVG--GY------ 427
Cdd:TIGR03423 231 TIDARLQQAAEKALGGR----------------------------------RGAVVVMDPRTGEILAMVStpSFdpnlfv 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 428 ------EYK--SSSP----INRAFSIYRQPGSTIKALVYALAMQEKIINPSTIVEDKA-IKIGGYSPKNWYKGYKGKVTA 494
Cdd:TIGR03423 277 dgisskDYKalLNDPdrplLNRAIQGVYPPGSTFKPVVALAALEEGVITPETRIYCPGyFQLGGRRFRCWKRGGHGRVDL 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 495 RQAFALSMNTIPVTLLQEIGMSKFTDTMAR--------------AAGL--TEAEMAQR------VGDRKNLAMALGAIEL 552
Cdd:TIGR03423 357 RKAIEESCDVYFYQLALRLGIDKIAEYAKRfgfgqktgidlpgeKSGLvpSREWKRKRfgqpwyPGDTLNVSIGQGYVLV 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 553 SPIELARIYATIASGGYAVEPVMILKVTDFDGNAIYTADQTKPRERLLDPVACAMVLNLMQAVI-SSEGTMPITAKEVSG 631
Cdd:TIGR03423 437 TPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPLPISPENLDVVREGMRDVVnGPGGTARRARLGLPY 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 632 IAGGKTGTVQSPSAAKAKWNNRSGI----RD-TWFVGALPQQ-----ISVIWvghERGapfaGSGSGTAGAVWKDFSKQY 701
Cdd:TIGR03423 517 KMAGKTGTAQVVSLKQGEKYDAEQIperlRDhALFVAFAPYDnpkiaVAVIV---EHG----GGGSSAAAPIARKIMDAY 589
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
436-615 |
1.29e-06 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 51.74 E-value: 1.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 436 NRAFSIYRQPGSTIKALVYALAMQEKIINPSTIVEDKAIKIGGYSPKNWYKGYKGKVT-----------ARQAFALSMNT 504
Cdd:PRK15105 295 NRAITDVFEPGSTVKPMVVMTALQRGVVKENSVLNTVPYRINGHEIKDVARYSELTLTgvlqkssnvgvSKLALAMPSSA 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504615179 505 IpVTLLQEIGMSKFTD--TMARAAGLTEAEmaQRVGDRKNLAMALG-AIELSPIELARIYATIASGGYAvEPVMILKVtd 581
Cdd:PRK15105 375 L-VDTYSRFGLGKATNlgLVGERSGLYPQK--QRWSDIERATFSFGyGLMVTPLQLARVYATIGSYGIY-RPLSITKV-- 448
|
170 180 190
....*....|....*....|....*....|....
gi 504615179 582 fdgnaiytaDQTKPRERLLDPVACAMVLNLMQAV 615
Cdd:PRK15105 449 ---------DPPVPGERVFPESIVRTVVHMMESV 473
|
|
| |
