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Conserved domains on  [gi|504557836|ref|WP_014744938|]
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ABC transporter permease [Tistrella mobilis]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 29-296 4.26e-99

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 292.40  E-value: 4.26e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  29 FLARALANPATVIGTLIVLALILAAALAPVLAPYDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLS 108
Cdd:COG1173    8 AWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 109 VAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLV 188
Cdd:COG1173   88 AVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 189 REREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWW 268
Cdd:COG1173  168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPW 247

                        250       260
                 ....*....|....*....|....*...
gi 504557836 269 VATLPGAAIFVVSMGFNLLGDGLRDVLD 296
Cdd:COG1173  248 LALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 29-296 4.26e-99

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 292.40  E-value: 4.26e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  29 FLARALANPATVIGTLIVLALILAAALAPVLAPYDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLS 108
Cdd:COG1173    8 AWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 109 VAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLV 188
Cdd:COG1173   88 AVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 189 REREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWW 268
Cdd:COG1173  168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPW 247

                        250       260
                 ....*....|....*....|....*...
gi 504557836 269 VATLPGAAIFVVSMGFNLLGDGLRDVLD 296
Cdd:COG1173  248 LALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
37-300 8.71e-79

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 241.64  E-value: 8.71e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  37 PATVIGTLIVLALILAAALAPVLAPYDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPV 116
Cdd:PRK09881  31 PLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMI 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 117 GLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQA 196
Cdd:PRK09881 111 GSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 197 ARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAA 276
Cdd:PRK09881 191 AKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAA 270

                        250       260
                 ....*....|....*....|....
gi 504557836 277 IFVVSMGFNLLGDGLRDVLDPRAQ 300
Cdd:PRK09881 271 ILLTAVGFNLFGDGIRDLLDPKAG 294
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 62-296 4.66e-74

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 228.04  E-value: 4.66e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836   62 YDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDI 141
Cdd:TIGR02790  24 HDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLAGYIGGRVDEAIMRVCDV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  142 VMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVI 221
Cdd:TIGR02790 104 FLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASHWQIIRRHILPNILSPII 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504557836  222 VRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVLD 296
Cdd:TIGR02790 184 VLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAFNLLGDALRDHLG 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 99-282 2.88e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 2.88e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  99 ARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFP--------RLVLALALAAVLGPGIGNAVVAIA 170
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPslvlglllVLLFGVLLGWGILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 171 VTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAqAPAP 250
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGP 159

                        170       180       190
                 ....*....|....*....|....*....|..
gi 504557836 251 EWGAMVATGRDYIIDqwWVATLPGAAIFVVSM 282
Cdd:cd06261  160 GTGLLLIFAILFPGD--LGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 117-298 1.92e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 64.63  E-value: 1.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  117 GLAIGI-AAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGI----GNAVVAIAVTGWPAYARLARAEAKLVRER 191
Cdd:pfam00528   1 GIPLGIiAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSIlghgILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  192 EFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFL----GLGAQAPAPEWGAMVAtgrdyiidqw 267
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP---------- 150

                         170       180       190
                  ....*....|....*....|....*....|.
gi 504557836  268 wVATLPGAAIFVVSMGFNLLGDGLRDVLDPR 298
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDPR 180
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 29-296 4.26e-99

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 292.40  E-value: 4.26e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  29 FLARALANPATVIGTLIVLALILAAALAPVLAPYDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLS 108
Cdd:COG1173    8 AWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 109 VAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLV 188
Cdd:COG1173   88 AVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 189 REREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWW 268
Cdd:COG1173  168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPW 247

                        250       260
                 ....*....|....*....|....*...
gi 504557836 269 VATLPGAAIFVVSMGFNLLGDGLRDVLD 296
Cdd:COG1173  248 LALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
37-300 8.71e-79

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 241.64  E-value: 8.71e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  37 PATVIGTLIVLALILAAALAPVLAPYDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPV 116
Cdd:PRK09881  31 PLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMI 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 117 GLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQA 196
Cdd:PRK09881 111 GSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 197 ARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAA 276
Cdd:PRK09881 191 AKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAA 270

                        250       260
                 ....*....|....*....|....
gi 504557836 277 IFVVSMGFNLLGDGLRDVLDPRAQ 300
Cdd:PRK09881 271 ILLTAVGFNLFGDGIRDLLDPKAG 294
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 62-296 4.66e-74

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 228.04  E-value: 4.66e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836   62 YDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDI 141
Cdd:TIGR02790  24 HDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLAGYIGGRVDEAIMRVCDV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  142 VMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVI 221
Cdd:TIGR02790 104 FLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASHWQIIRRHILPNILSPII 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504557836  222 VRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVLD 296
Cdd:TIGR02790 184 VLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAFNLLGDALRDHLG 258
nikC PRK10417
nickel transporter permease NikC; Provisional
 62-297 4.85e-68

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 212.99  E-value: 4.85e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  62 YDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDI 141
Cdd:PRK10417  29 YDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADM 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 142 VMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVI 221
Cdd:PRK10417 109 FMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLL 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504557836 222 VRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVLDP 297
Cdd:PRK10417 189 VLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGLALFISVMAFNLLGDALRDHLDP 264
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
79-298 9.40e-59

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 190.38  E-value: 9.40e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  79 EHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVL 158
Cdd:PRK10913  78 AHILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIF 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 159 GPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGL 238
Cdd:PRK10913 158 GPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAAL 237

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 239 GFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVLDPR 298
Cdd:PRK10913 238 GFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPK 297
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 62-298 4.62e-57

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 186.09  E-value: 4.62e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  62 YDPIDQVLNDRLQA-PGAEHFLGTDHLGRDILSRILYGARITLAV-VLSVAvIVGPVGLAIGIAAGYFGGRVDAVLMGLT 139
Cdd:PRK15082  61 YDAENYFDYDALNAgPSLQHWFGVDSLGRDIFSRILVGARISLAAgFFSVA-IGAAIGTVLGLLAGYYEGWWDRIIMRIC 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 140 DIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSS 219
Cdd:PRK15082 140 DVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSS 219

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504557836 220 VIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVLDPR 298
Cdd:PRK15082 220 IVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPK 298
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
62-298 5.00e-43

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 149.20  E-value: 5.00e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  62 YDPIDQVLNDRLQAP------GAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVL 135
Cdd:COG4171   52 YSPDQQFIGALLLPPswddngDVSFFLGTDDLGRDILSRLLYGARYTFGSALLVVLAAAIIGGIIGILAGMSRGLKSSIL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 136 MGLTDIVMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPL 215
Cdd:COG4171  132 NHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALLPQFIHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPN 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 216 CLSSVIVRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVL 295
Cdd:COG4171  212 ILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLGDSLELIYLAPWTVILPGLAIMFSVLIVNLVGDGLRRAL 291


                 ...
gi 504557836 296 DPR 298
Cdd:COG4171  292 NKG 294
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 62-298 6.86e-39

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 138.82  E-value: 6.86e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  62 YDPIDQVLNDRLQAPGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDI 141
Cdd:PRK15406  64 YDDTDWGMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEI 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 142 VMAFPRLVLALALAAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVI 221
Cdd:PRK15406 144 LNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVV 223

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504557836 222 VRLTLDMAGVILIFAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLRDVLDPR 298
Cdd:PRK15406 224 VYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 75-298 2.98e-36

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 132.58  E-value: 2.98e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  75 APGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALAL 154
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIIL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 155 AAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILI 234
Cdd:COG4239  196 SSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFLPFILSGAITT 275

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504557836 235 FAGLGFLGLGAQAPAPEWGAMVATGRDYiIDQWWVATlpgAAIFVVSMGFNLL---GDGLRDVLDPR 298
Cdd:COG4239  276 LTSLDFLGFGLPPGSPSLGELLAQGKNN-LQAPWLGL---SAFVVLALMLSLLvfiGEAVRDAFDPR 338
PRK15111 PRK15111
peptide ABC transporter permease SapC;
81-292 4.14e-35

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 128.67  E-value: 4.14e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  81 FLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGP 160
Cdd:PRK15111  77 FLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGP 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 161 GIGNAVVAIAVTGWPayaRLARAEAKLVR---EREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAG 237
Cdd:PRK15111 157 SLSHAMFAVWLALLP---RMVRSIYSAVHdelEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAA 233

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 504557836 238 LGFLGLGAQAPAPEWGAMVATGRDYIIDQWWVATLPGAAIFVVSMGFNLLGDGLR 292
Cdd:PRK15111 234 LGFLDLGAQLPSPEWGAMLGDSLELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIR 288
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 75-297 9.34e-23

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 96.21  E-value: 9.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  75 APGAEHFLGTDHLGRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFPRLVLALAL 154
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 155 AAVLGPGIGNAVVAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILI 234
Cdd:PRK15021 196 SSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITT 275

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504557836 235 FAGLGFLGLGAQAPAPEWGAMVATGRDYIIDQWwvatLPGAAIFVVSMGFNLL---GDGLRDVLDP 297
Cdd:PRK15021 276 LTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPW----LGITAFLSVAILLSLLifiGEAVRDAFDP 337
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 99-282 2.88e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 2.88e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  99 ARITLAVVLSVAVIVGPVGLAIGIAAGYFGGRVDAVLMGLTDIVMAFP--------RLVLALALAAVLGPGIGNAVVAIA 170
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPslvlglllVLLFGVLLGWGILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 171 VTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFLGLGAqAPAP 250
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE-APGP 159

                        170       180       190
                 ....*....|....*....|....*....|..
gi 504557836 251 EWGAMVATGRDYIIDqwWVATLPGAAIFVVSM 282
Cdd:cd06261  160 GTGLLLIFAILFPGD--LGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 117-298 1.92e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 64.63  E-value: 1.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  117 GLAIGI-AAGYFGGRVDAVLMGLTDIVMAFPRLVLALALAAVLGPGI----GNAVVAIAVTGWPAYARLARAEAKLVRER 191
Cdd:pfam00528   1 GIPLGIiAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSIlghgILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  192 EFVQAARLAGASDLRILVLHVAPLCLSSVIVRLTLDMAGVILIFAGLGFL----GLGAQAPAPEWGAMVAtgrdyiidqw 267
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP---------- 150

                         170       180       190
                  ....*....|....*....|....*....|.
gi 504557836  268 wVATLPGAAIFVVSMGFNLLGDGLRDVLDPR 298
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDPR 180
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 88-302 9.29e-09

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 55.46  E-value: 9.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836  88 GRDILSRILYGARITLAVVLSVAVIVGPVGLAIGIAAGYF-GGRVDAVLMGLTDIVMAFPR------------------- 147
Cdd:COG0601   84 GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPSfwlglllillfavklgwlp 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 148 LVLALALAAVLGPGIGNAV---VAIAVTGWPAYARLARAEAKLVREREFVQAARLAGASDLRILVLHVAPLCLSSVIVRL 224
Cdd:COG0601  164 VSGRVSPWEDFLDALRHLIlpaLTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVL 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504557836 225 TLDMAGVI-------LIFA--GLGFLGLGAqapapewgamvATGRDYIIDQwwVATLPGAAIFVVsmgFNLLGDGLRDVL 295
Cdd:COG0601  244 GLQLGGLLggavvveTVFSwpGLGRLLVDA-----------ILNRDYPVVQ--GIVLLIAVLVVL---VNLLVDLLYALL 307


                 ....*..
gi 504557836 296 DPRAQTG 302
Cdd:COG0601  308 DPRIRLG 314
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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