|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
4-1063 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 933.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 4 LVKTALHKPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTtVNDIEHIE 83
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNG-VEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 84 SQSLPGMGIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSASTVPILQMAFSSPSLSEAKIRDLVQNNI 163
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAERNI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 164 RLPLSALPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTILLNNSPKAIDELN 243
Cdd:COG0841 162 KDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEFE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 244 DLPIKTVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLLGD 323
Cdd:COG0841 242 NIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIVYD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 324 ASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDD 403
Cdd:COG0841 322 QSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDD 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 404 ATVTIENINWHLEQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLV 483
Cdd:COG0841 402 AIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLT 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 484 PTLAMFLLKPHRPEPGAGhhpedafinhhegeqhpkprnallqsvlnFQQGFERHFSNVRDTYHGLLTLALGARKRFIVG 563
Cdd:COG0841 482 PALCARLLKPHPKGKKGR-----------------------------FFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLV 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 564 FLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEARIREVipaEELDTIVDNIGiplsgidma 643
Cdd:COG0841 533 ALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEV---PEVESVFSVVG--------- 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 644 ySSSGTIGPQDGDIQVSLKTH---HAPTADYVKKLREALPQsFPGSHFAFLPAdissQILNFGAPAPLDVKISGRNDAEN 720
Cdd:COG0841 601 -FSGGGSGSNSGTIFVTLKPWderDRSADEIIARLREKLAK-IPGARVFVFQP----PAGGLGSGAPIEVQLQGDDLEEL 674
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 721 RAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMVASLAGSsqTAPTFWLnpaNGVSYSI 800
Cdd:COG0841 675 AAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGR--YVNDFNR---GGREYDV 749
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 801 VAATPQYRLDSLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANV-QGRDLGGVARDVQKVLDDT 879
Cdd:COG0841 750 RVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLaPGVSLGEALAAIEELAAEL 829
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 880 AsmRPKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSGTSLSVPA 959
Cdd:COG0841 830 K--LPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYS 907
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 960 LTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPLAISE----EQNAPLGRAVI 1035
Cdd:COG0841 908 QIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTgagaEFRQPLGIAVI 987
|
1050 1060
....*....|....*....|....*...
gi 504531890 1036 GGLVFATVATLLFVPVVFSLVHGRHPTR 1063
Cdd:COG0841 988 GGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
4-1066 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 594.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 4 LVKTALHKPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTTVNdIEHIE 83
Cdd:COG3696 5 IIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPG-VKEVR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 84 SQSLPGMGIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSAsTVPILQMAFSSPS--LSEAKIRDLVQN 161
Cdd:COG3696 84 SISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTG-LGEIYQYTLESDPgkYSLMELRTLQDW 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 162 NIRLPLSALPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTI----LLNNspk 237
Cdd:COG3696 163 VIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVrgigLIRS--- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 238 aIDELNDLPIKTVDGALITIGQVAHVRDGSPPQTNIVRVDGHR-AVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSL 316
Cdd:COG3696 240 -LEDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGeVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 317 KTSLLGDASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALA 396
Cdd:COG3696 319 KIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAID 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 397 VGILVDDATVTIENI------NWHLEQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIF 470
Cdd:COG3696 399 FGIIVDGAVVMVENIlrrleeNRAAGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIF 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 471 AMASSFILSRTLVPTLAMFLLKPHRPEpgaghhpEDAFINHhegeqhpkprnallqsvlnfqqGFERHfsnvrdtYHGLL 550
Cdd:COG3696 479 ALLGALLLSLTLVPVLASLLLRGKVPE-------KENPLVR----------------------WLKRL-------YRPLL 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 551 TLALGARKRFIVGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEARIREViPaeELDTIV 630
Cdd:COG3696 523 RWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSF-P--EVESVV 599
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 631 DNIGIPLSGIDMAysssgtiGPQDGDIQVSLK-----THHAPTADYVKKLREALpQSFPGSHFAFlpadisSQ--ILNF- 702
Cdd:COG3696 600 SRTGRAEDATDPM-------GVNMSETFVILKprsewRSGRTKEELIAEMREAL-EQIPGVNFNF------SQpiQMRVd 665
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 703 ----GAPAPLDVKISGRNDAENRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMVASL 778
Cdd:COG3696 666 ellsGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAI 745
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 779 AGssQTAPTFWLNPAngvSYSIVAA-TPQYRlDSLPSLEALPVTGANGqAQI-LGGVATISRVQSPAVVTHYNIEPTLDL 856
Cdd:COG3696 746 GG--KAVGQVYEGER---RFDIVVRlPEELR-DDPEAIRNLPIPTPSG-AQVpLSQVADIEVVEGPNQISRENGRRRIVV 818
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 857 YANVQGRDLGGVARDVQKVLDDTASMrPKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITA 936
Cdd:COG3696 819 QANVRGRDLGSFVAEAQAKVAEQVKL-PPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLN 897
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 937 LPAALAGIVWMLFLSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMIIG 1016
Cdd:COG3696 898 VPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALG 977
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|....*
gi 504531890 1017 MLPLAI-----SEEQnAPLGRAVIGGLVFATVATLLFVPVVFSLVHGRHPTRATA 1066
Cdd:COG3696 978 LLPMALstgpgSEVQ-RPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-1057 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 585.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 4 LVKTALHKPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTTVNdIEHIE 83
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDG-LKYMS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 84 SQSLPGMGIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSASTVPILQMAFSSP--SLSEAKIRDLVQN 161
Cdd:pfam00873 80 SQSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPdgSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 162 NIRLPLSALPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTILLNNSPKAIDE 241
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 242 LNDLPIKTVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLL 321
Cdd:pfam00873 240 FEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 322 GDASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILV 401
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 402 DDATVTIENINWHL-EQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSR 480
Cdd:pfam00873 400 DDAIVVVENIERVLeENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 481 TLVPTLAMFLLKPHRPEPGAGhhpedafinhhegeqhpkprnallqsvlnFQQGFERHFSNVRDTYHGLLTLALGARKRF 560
Cdd:pfam00873 480 TLTPALCATLLKPRREPKHGG-----------------------------FFRWFNRMFDRLTRGYAKLLAKVLRHTAVV 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 561 IVGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEARIREVipaEELDTIVDNIGIPLSGI 640
Cdd:pfam00873 531 LLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEK---PEVESVFAVTGFAFSGD 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 641 DMaysssgtiGPQDGDIQVSLK------THHAPTADYVKKLREALPQsFPGSHFAFL-PADISSQILNFGAPAPLDVKIS 713
Cdd:pfam00873 608 NN--------GPNSGDAFISLKpwkerpGPEKSVQALIERLRKALKQ-IPGANVFLFqPIQLRGLGTISGFRSDLQVKIF 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 714 GRNDAENRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVtNSMVASLAGSSQtAPTFwlnPA 793
Cdd:pfam00873 679 GDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDI-NDTLSTALGGSY-VNDF---PE 753
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 794 NGVSYS-IVAATPQYRLdSLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANVQGRDLGGVARDV 872
Cdd:pfam00873 754 GGRVYDvVVQLPEDFRS-SPEDIGQLYVRNPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEA 832
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 873 QKVLDDTASMrPKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSG 952
Cdd:pfam00873 833 MAQIAKQVKL-PPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRG 911
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 953 TSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAA-LEAGYTRFRPVCMTALAMIIGMLPLAI-----SEEQ 1026
Cdd:pfam00873 912 LPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSLEEAiLEACRLRLRPILMTALAAILGVLPLALstgagSELQ 991
|
1050 1060 1070
....*....|....*....|....*....|.
gi 504531890 1027 NaPLGRAVIGGLVFATVATLLFVPVVFSLVH 1057
Cdd:pfam00873 992 Q-PLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
11-1056 |
3.66e-147 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 466.03 E-value: 3.66e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 11 KPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTtVNDIEHIESQSLPGM 90
Cdd:NF033617 7 RPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQ-IEGIDEMTSQSSLGY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 91 GIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGI-TPPLILNYSASTVPILQMAFSSPSLSEAKIRDLVQNNIRLPLSA 169
Cdd:NF033617 86 STITLQFRLGTDLDVALSEVQAAINAAQSLLPSEApDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLAPKLSQ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 170 LPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTILLNNSPKAIDELNDLPIK- 248
Cdd:NF033617 166 INGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKy 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 249 TVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLLGDASAFV 328
Cdd:NF033617 246 ADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 329 KQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDATVTI 408
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 409 ENINWHLEQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLVPTLAM 488
Cdd:NF033617 406 ENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCS 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 489 FLLKpHRPEPGaghhpedafinhhegeqhpkprnallqsvlNFQQGFERHFSNVRDTYHGLLTLALGARKRFIVGFLACV 568
Cdd:NF033617 486 RLLK-ANEKPG------------------------------RFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 569 LASFLLLPSLGQDFFPATDAGALALHVRLPlgtrieeSAAAFDRIEARIREvipaeeldtiVDNIGIPLSGIDMAYS--- 645
Cdd:NF033617 535 ALLPLLYVFIPKELAPSEDRGVIFGMIQAP-------QSISLDYMSAKMRD----------VEKILSSDPEVQSLTSfng 597
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 646 SSGTIGPQDGDIQVSLKTH---HAPTADYVKKLREALpQSFPGSH---FAFLPADISSQilnfGAPAPLDVKISGRNDAE 719
Cdd:NF033617 598 VGGNPGDNTGFGIINLKPWderDVSAQEIIDRLRPKL-AKVPGMDlflFPLQDLPGGAG----SSLPQYQVTLTPSDYDS 672
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 720 NRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMVASLAGSSQTapTFWLnpaNGVSYS 799
Cdd:NF033617 673 LFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVN--TIYT---DGNQYK 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 800 IVA-ATPQYRLDsLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANVQGRDLGGVArdVQKVLDD 878
Cdd:NF033617 748 VVLeVDRRYRLN-PEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEA--IEALDQA 824
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 879 TASMRPKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSGTSLSVP 958
Cdd:NF033617 825 AKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIY 904
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 959 ALTGAILCMGVATANSILVVSFCRERLAEHG-DALKAALEAGYTRFRPVCMTALAMIIGMLPLAIS----EEQNAPLGRA 1033
Cdd:NF033617 905 AQIGLITLIGLVKKNGILMVEFANELQRHQGlSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLStgagAESRFPLGIV 984
|
1050 1060
....*....|....*....|...
gi 504531890 1034 VIGGLVFATVATLLFVPVVFSLV 1056
Cdd:NF033617 985 IVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
13-1059 |
5.64e-131 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 424.17 E-value: 5.64e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 13 YTFIVL--AIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTtVNDIEHIESQSLPGM 90
Cdd:TIGR00914 12 QRWLVLlaTLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAG-LPGLETTRSLSRYGL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 91 GIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPL---------ILNYSA---STVPILQMAFSSPslseAKIRDL 158
Cdd:TIGR00914 91 SQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMgpistglgeIFLYTVeaeEGARKKDGGAYTL----TDLRTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 159 VQNNIRLPLSALPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTILLNNSPKA 238
Cdd:TIGR00914 167 QDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 239 IDELNDLPIKTVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKT 318
Cdd:TIGR00914 247 MDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVEI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 319 SLLGDASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGglALAVG 398
Cdd:TIGR00914 327 VTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLG--ALDFG 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 399 ILVDDATVTIENINWHLEQGKAVKAAILD----------GAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAV 468
Cdd:TIGR00914 405 LIVDGAVVIVENAHRRLAEAQHHHGRQLTlkerlhevfaASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFTV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 469 IFAMASSFILSRTLVPTLAMFLLKPHRPEpgaghhpEDAFINHHegeqhpkprnallqsvlnfqqgferhfsnVRDTYHG 548
Cdd:TIGR00914 485 VLALAGAMILSLTFVPAAVALFIRGKVAE-------KENRLMRV-----------------------------LKRRYEP 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 549 LLTLALGARKRFIVGFLACVLASFLLLPSLGQDFFPATDAGALALH-VRLPlGTRIEESAAAFDRIEARIREVipaEELD 627
Cdd:TIGR00914 529 LLERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDLAYQaLRIP-GTSLAQSVAMQQTLEKLIKSF---PEVA 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 628 TIVDNIGiplsgidMAYSSSGTIGPQDGDIQVSLKTH------HAPTADYVKKLREALpQSFPGSHFAFL-PADISSQIL 700
Cdd:TIGR00914 605 RVFAKTG-------TAEIATDPMPPNASDTYIILKPEsqwpegKKTKEDLIEEIQEAT-VRIPGNNYEFTqPIQMRFNEL 676
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 701 NFGAPAPLDVKISGRNDAENRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMVASLAG 780
Cdd:TIGR00914 677 ISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGG 756
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 781 SsQTAPTFwlnpaNGVS-YSIVAATPQYRLDSLPSLEALPV----TGANGQAQI-LGGVATISRVQSPAVVTHYNIEPTL 854
Cdd:TIGR00914 757 R-MSGETF-----EGDRrFDIVIRLPESLRESPQALRQLPIplplSEDARKQFIpLSDVADLRVSPGPNQISRENGKRRV 830
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 855 DLYANVQGRDLGGVARDVQKVLDDTASMRPkGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVII 934
Cdd:TIGR00914 831 VVSANVRGRDLGSFVDDAKKAIAEQVKLPP-GYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVF 909
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 935 TALPAALAGIVWMLFLSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMI 1014
Cdd:TIGR00914 910 TGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVAS 989
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*....
gi 504531890 1015 IGMLPLAIS----EEQNAPLGRAVIGGLVFATVATLLFVPVVFSLVHGR 1059
Cdd:TIGR00914 990 LGFVPMAIAtgtgAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRR 1038
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
17-1071 |
1.08e-100 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 341.71 E-value: 1.08e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 17 VLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLsTTVNDIEHIESQSLP-GMGIVKI 95
Cdd:TIGR00915 14 VIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNM-NGIDGLRYMSSSSDSdGSMTITL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 96 FFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSASTVPILQMAFSSP--SLSEAKIRDLVQNNIRLPLSALPGL 173
Cdd:TIGR00915 93 TFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDdgSMTKEDLSDYAASNMVDPLSRLEGV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 174 AmPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNqiIPVGTAKLG---------LNEyTILLNNSPKAIDELND 244
Cdd:TIGR00915 173 G-DVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQN--AQISAGQLGglpavpgqqLNA-TIIAQTRLQTPEQFEN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 245 LPIKT-VDGALITIGQVAHVRDGSPPQTNIVRVDGHRAV-LMPALKNGSiSTLSIIDGIRQMLPRINETLPPSLKTSLLG 322
Cdd:TIGR00915 249 ILLKVnTDGSQVRLKDVARVELGGENYSISARFNGKPASgLAIKLATGA-NALDTAKAVKAELAVLEPFFPQGMKYVYPY 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 323 DASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVD 402
Cdd:TIGR00915 328 DTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVD 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 403 DATVTIENINWHL-EQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRT 481
Cdd:TIGR00915 408 DAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALI 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 482 LVPTLAMFLLKPHRpepgAGHHPEDAfinhhegeqhpkprnallqsvLNFQQGFERHFSNVRDTYHGLLTLALGARKRFI 561
Cdd:TIGR00915 488 LTPALCATMLKPIE----KGEHHEKK---------------------GGFFGWFNRMFDSSTHGYENGVGKILRRRGRYL 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 562 VGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEARIREViPAEELDTIVDNIGIPLSGid 641
Cdd:TIGR00915 543 LVYVLLVGGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAK-EKANVESVFTVNGFSFAG-- 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 642 maysssgtIGPQDGDIQVSLK---THHAPTADYV---KKLREALPQSFPGSHFAFLPadisSQILNFGAPAPLDVKISGR 715
Cdd:TIGR00915 620 --------RGQNMGMAFIRLKdweERTGKENSVFaiaGRATGHFMQIKDAMVIAFVP----PAILELGNATGFDFFLQDR 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 716 NDAENRAYAVELERRLQHVPGIADLRIQQSTGY---PSLQVNVDRMRANGLGITERDVTNSMVASLAGSsqtaptfWLN- 791
Cdd:TIGR00915 688 AGLGHEALLQARNQLLGLAAQNPALTRVRPNGLedePQLKIDIDREKAQALGVSIADINTTLSTAWGSS-------YVNd 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 792 -PANGVSYSI-VAATPQYRldSLPS-LEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLdlyaNVQGRDLGGV 868
Cdd:TIGR00915 761 fIDRGRVKRVyVQAEEDAR--MSPEdINKWYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSM----EILGSAAPGV 834
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 869 AR-DVQKVLDDTASMRPKGATISLHGQidALHEAFSG----LSFGLlgAVVLIYLLIVVNFQSWADPFVIITALPAALAG 943
Cdd:TIGR00915 835 STgQAMAAMEAIAQKLPPGFGFSWTGM--SYEERLSGsqapALYAL--SLLVVFLCLAALYESWSIPVSVMLVVPLGIIG 910
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 944 IVWMLFLSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPLAIS 1023
Cdd:TIGR00915 911 ALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAIS 990
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|...
gi 504531890 1024 E-----EQNApLGRAVIGGLVFATVATLLFVPVVFSLVHGRHPTRATAGETPH 1071
Cdd:TIGR00915 991 TgagsgSQHA-IGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEKEMSV 1042
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
17-1059 |
6.68e-80 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 282.90 E-value: 6.68e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 17 VLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTtVNDIEHIESQSLPGMGIVKIF 96
Cdd:PRK09577 14 VISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNG-APGLLYTSATSSAGQASLSLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 97 FQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLI-LNYSASTVP-ILQMAFSSPSLSEAKIRDLVQNNIRLPLSALPGLA 174
Cdd:PRK09577 93 FKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIqVEKAADNIQlIVSLTSDDGRLTGVELGEYASANVLQALRRVEGVG 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 175 mPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGtaKLGLNEytiLLNNSPKAIDELNDLPIKT----- 249
Cdd:PRK09577 173 -KVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIG--DIGRSA---VPDSAPIAATVFADAPLKTpedfg 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 250 -------VDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMP-ALKNGSiSTLSIIDGIRQMLPRINETLPPSLKTSLL 321
Cdd:PRK09577 247 aialrarADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGiKLAPGS-NAVATEKRVRATMDELSRYFPPGVKYQIP 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 322 GDASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILV 401
Cdd:PRK09577 326 YETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 402 DDATVTIENIN-WHLEQGKAVKAAILDGAAQIVGpAFVSLLCICI-VFVPMFLLQGIAGYLFRPMALAVIFAMASSFILS 479
Cdd:PRK09577 406 DDAIVVVENVErLMVEEGLSPYDATVKAMKQISG-AIVGITVVLTsVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAFLA 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 480 RTLVPTLAMFLLKPhrpePGAGHHPEDAFINhhegeqhpkprnallqsvlnfqqGFERHFSNVRDTYHGLLTLALGARKR 559
Cdd:PRK09577 485 LSLTPALCATLLKP----VDGDHHEKRGFFG-----------------------WFNRFVARSTQRYATRVGAILKRPLR 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 560 FIVGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEARIREVIPAEeldtIVDNIGiplsg 639
Cdd:PRK09577 538 WLVVYGALTAAAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVA----YTFALG----- 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 640 idmAYSSSGTiGPQDGDIQVSLKTHHAPTA--DYVKKLREALPQSFPGSHFAFLPADISSQILNFGAPAPLDVKISGRND 717
Cdd:PRK09577 609 ---GFNLYGE-GPNGGMIFVTLKDWKERKAarDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGG 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 718 AENRAYAVELERRLQHV---PGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVtNSMVASLAGSSQTAPTFWlnpAN 794
Cdd:PRK09577 685 LGYAAFVAAREQLLAEGakdPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEI-NTTLAVMFGSDYIGDFMH---GS 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 795 GVSYSIVAATPQYRLDsLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANVQ-GRDLGGVARDVQ 873
Cdd:PRK09577 761 QVRRVIVQADGRHRLD-PDDVKKLRVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAApGHSSGEAMAAIE 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 874 KVlddtASMRPKGATISLHGQidALHEAFSG----LSFGLlgAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLF 949
Cdd:PRK09577 840 RI----AATLPAGIGYAWSGQ--SFEERLSGaqapMLFAL--SVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVT 911
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 950 LSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPLAI-----SE 1024
Cdd:PRK09577 912 LRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFasgaaSG 991
|
1050 1060 1070
....*....|....*....|....*....|....*
gi 504531890 1025 EQNApLGRAVIGGLVFATVATLLFVPVVFSLVhGR 1059
Cdd:PRK09577 992 AQIA-IGTGVLGGVITATVLAVFLVPLFFVVV-GR 1024
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
9-1071 |
5.04e-79 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 280.18 E-value: 5.04e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 9 LHKPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTTvNDIEHIESQSLP 88
Cdd:PRK09579 8 IRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASA-EGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 89 GMGIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSASTVPILQMAFSSPSLSEAKIRDLVQNNIRLPLS 168
Cdd:PRK09579 87 NFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSEEMSNPQITDYLSRVIQPKLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 169 ALPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTILLNNSPKAIDELNDLPIK 248
Cdd:PRK09579 167 TLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIPVK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 249 TVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLLGDASAFV 328
Cdd:PRK09579 247 TSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATLFI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 329 KQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDATVTI 408
Cdd:PRK09579 327 QASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 409 ENINWHLEQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLVPTLAM 488
Cdd:PRK09579 407 ENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCA 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 489 FLLKPHRPEPGAGHHpedafinhhegeqhpkprnallqsvlnfqqgFERHFSNVRDTYHGLLTLALGARKRFIVgFLACV 568
Cdd:PRK09579 487 LLLRHEENPSGLAHR-------------------------------LDRLFERLKQRYQRALHGTLNTRPVVLV-FAVIV 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 569 LASFLLLPSLGQ-DFFPATDAGALALHVRLPlgtrieeSAAAFDRIEARIREVIPaeeldtivdnigiPLSGIDMAYSS- 646
Cdd:PRK09579 535 LALIPVLLKFTQsELAPEEDQGIIFMMSSSP-------QPANLDYLNAYTDEFTP-------------IFKSFPEYYSSf 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 647 --SGTIGPQDGDIQVSLKthhaPTADYVKKLREALP------QSFPGSH-FAF-LPAdissqILNFGAPAPLDVKISGRN 716
Cdd:PRK09579 595 qiNGFNGVQSGIGGFLLK----PWNERERTQMELLPlvqaklEEIPGLQiFGFnLPS-----LPGTGEGLPFQFVINTAN 665
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 717 DAEN-RAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMvASLAGSSQTApTFWLnpaNG 795
Cdd:PRK09579 666 DYESlLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTL-ATLLGEGEIN-RFTI---DG 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 796 VSYSIVAATPQYRLDSLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTldlyANVQGRDLGGVARDVQKV 875
Cdd:PRK09579 741 RSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQLNQFQQLNS----AIISGFPIVSMGEAIETV 816
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 876 LDDTASMRPKGATISLHGQIDALHEAFSGL--SFGLlgAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSGT 953
Cdd:PRK09579 817 QQIAREEAPEGFAFDYAGASRQYVQEGSALwvTFGL--ALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVS 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 954 SLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALE-AGYTRFRPVCMTALAMIIGMLPLAISEEQNA---- 1028
Cdd:PRK09579 895 SMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRREAIEeAAAIRLRPVLMTTAAMVFGMVPLILATGAGAvsrf 974
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|...
gi 504531890 1029 PLGRAVIGGLVFATVATLLFVPVVFSLVHGRHPTRATAGETPH 1071
Cdd:PRK09579 975 DIGLVIATGMSIGTLFTLFVLPCIYTLLAKPDAAPGVAQAANA 1017
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
17-1063 |
2.12e-77 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 275.56 E-value: 2.12e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 17 VLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLsTTVNDIEHIESQSL-PGMGIVKI 95
Cdd:PRK10555 14 VLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNM-TGLDNLMYMSSQSSgTGQASVTL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 96 FFQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSASTVPILQMAFSSP--SLSEAKIRDLVQNNIRLPLSALPGL 173
Cdd:PRK10555 93 SFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTdgSMDKQDIADYVASNIQDPLSRVNGV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 174 AMPTPMGgKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGtaKLG---------LNEyTILLNNSPKAIDELND 244
Cdd:PRK10555 173 GDIDAYG-SQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVG--QLGgtpsvdkqaLNA-TINAQSLLQTPEQFRD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 245 LPIKT-VDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLLGD 323
Cdd:PRK10555 249 ITLRVnQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLEYKVAYE 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 324 ASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDD 403
Cdd:PRK10555 329 TTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDD 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 404 ATVTIENINWHL-EQGKAVKAAILDGAAQIVGpAFVSL-LCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRT 481
Cdd:PRK10555 409 AIVVVENVERIMsEEGLTPREATRKSMGQIQG-ALVGIaMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAMI 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 482 LVPTLAMFLLKPhrpepgaghhpedafinHHEGEQHPKPrnallqsvlNFQQGFERHFSNVRDTYHGLLTLALGARKRFI 561
Cdd:PRK10555 488 LTPALCATLLKP-----------------LKKGEHHGQK---------GFFGWFNRMFNRNAERYEKGVAKILHRSLRWI 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 562 VGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEariREVIPAEEldtivDNIgipLSGID 641
Cdd:PRK10555 542 LIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVE---KYYFTHEK-----DNV---MSVFA 610
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 642 MAYSSSGTIGPQDGDIQVSLKTHHAPTAD------YVKKLREALPQSFPGSHFAFLPADISSqilnFGAPAPLDVKISGR 715
Cdd:PRK10555 611 TVGSGPGGNGQNVARMFIRLKDWDERDSKtgtsfaIIERATKAFNKIKEARVIASSPPAISG----LGSSAGFDMELQDH 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 716 NDAENRAYAVELERRLQHV---PGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVtNSMVASLAGSSQTAPtfWLNP 792
Cdd:PRK10555 687 AGAGHDALMAARNQLLALAaknPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDI-NDTLQTAWGSSYVND--FMDR 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 793 ANgVSYSIVAATPQYRLdsLPS-LEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANVQGRDLGGVARD 871
Cdd:PRK10555 764 GR-VKKVYVQAAAPYRM--LPDdINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMD 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 872 VQKVLddtASMRPKGatISLHGQIDALHEAFSGLSFGLLGAVVL--IYLLIVVNFQSWADPFVIITALPAALAGIVWMLF 949
Cdd:PRK10555 841 IMESL---VKQLPNG--FGLEWTAMSYQERLSGAQAPALYAISLlvVFLCLAALYESWSVPFSVMLVVPLGVIGALLATW 915
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 950 LSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPLAISE----- 1024
Cdd:PRK10555 916 MRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTgagsg 995
|
1050 1060 1070
....*....|....*....|....*....|....*....
gi 504531890 1025 EQNApLGRAVIGGLVFATVATLLFVPVVFSLVHGRHPTR 1063
Cdd:PRK10555 996 SQHA-VGTGVMGGMISATILAIFFVPLFFVLVRRRFPLK 1033
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
11-1055 |
1.43e-74 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 267.37 E-value: 1.43e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 11 KPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTtVNDIEHIESQSLPGM 90
Cdd:PRK10503 19 RPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQ-MSGLKQMSSQSSGGA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 91 GIVKIFFQPGVDIRTANAQVTAVSQTVLKQMPPGI-TPPLILNYSASTVPILQMAFSSPSLSEAKIRDLVQNNIRLPLSA 169
Cdd:PRK10503 98 SVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLpNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQ 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 170 LPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNqiipVGTAKLGLN----EYTILLNNSPKAIDELNDL 245
Cdd:PRK10503 178 VSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGAN----VNSAKGSLDgptrAVTLSANDQMQSAEEYRQL 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 246 PIKTVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLLGDAS 325
Cdd:PRK10503 254 IIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRT 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 326 AFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDAT 405
Cdd:PRK10503 334 TNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAI 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 406 VTIENINWHLEQGKAVKAAILDGAAQIvGPAFVSLLCICI-VFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLVP 484
Cdd:PRK10503 414 VVIENISRYIEKGEKPLAAALKGAGEI-GFTIISLTFSLIaVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTP 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 485 TLAMFLLKPHrpepgaghhpedAFINHHEgeqhpkprnallqsvlnFQQGFERHFSNVRDTYHGLLTLALGARKRFIVGF 564
Cdd:PRK10503 493 MMCARMLSQE------------SLRKQNR-----------------FSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVA 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 565 LACVLASFLLLPSLGQDFFPATDAGALAlhvrlplGTRIEESAAAFDRIEARIREVIPAEELDTIVDNIgIPLSGIDMAY 644
Cdd:PRK10503 544 LSTLLLTVLLWIFIPKGFFPVQDNGIIQ-------GTLQAPQSSSFANMAQRQRQVADVILQDPAVQSL-TSFVGVDGTN 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 645 SSSGTigpqdGDIQVSLKthhaPTADYVKKLREALPQ------SFPGSHFAFLPAD---ISSQIlnfgAPAPLDVKISGR 715
Cdd:PRK10503 616 PSLNS-----ARLQINLK----PLDERDDRVQKVIARlqtavaKVPGVDLYLQPTQdltIDTQV----SRTQYQFTLQAT 682
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 716 NDAENRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMVASLAgssQTAPTFWLNPANg 795
Cdd:PRK10503 683 SLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFG---QRLISTIYTQAN- 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 796 vSYSIVAATPQYRLDSLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANV-QGRDLGgvaRDVQK 874
Cdd:PRK10503 759 -QYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVpDGYSLG---DAVQA 834
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 875 VLDDTASMR-PKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSGT 953
Cdd:PRK10503 835 IMDTEKTLNlPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGS 914
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 954 SLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAAL-EAGYTRFRPVCMTALAMIIGMLPLAISE----EQNA 1028
Cdd:PRK10503 915 ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIyQACLLRFRPILMTTLAALLGALPLMLSTgvgaELRR 994
|
1050 1060
....*....|....*....|....*..
gi 504531890 1029 PLGRAVIGGLVFATVATLLFVPVVFSL 1055
Cdd:PRK10503 995 PLGICMVGGLIVSQVLTLFTTPVIYLL 1021
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
17-1071 |
1.81e-74 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 267.15 E-value: 1.81e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 17 VLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYnglsPDAMAGRVIYTYERSLSTTVNDIEHI--ESQSLPGMGIVK 94
Cdd:PRK15127 14 VIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASY----PGADAKTVQDTVTQVIEQNMNGIDNLmyMSSNSDSTGTVQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 95 IF--FQPGVDIRTANAQVTAVSQTVLKQMPPGITPPLILNYSASTVPILQMAFSS--PSLSEAKIRDLVQNNIRLPLSAL 170
Cdd:PRK15127 90 ITltFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINtdGTMTQEDISDYVAANMKDPISRT 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 171 PGLAmPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGtaKLG---------LNEyTILLNNSPKAIDE 241
Cdd:PRK15127 170 SGVG-DVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAG--QLGgtppvkgqqLNA-SIIAQTRLTSTEE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 242 LNDLPIKT-VDGALITIGQVAHVRDGSPPQTNIVRVDGHRAV-LMPALKNGSiSTLSIIDGIRQMLPRINETLPPSLKTS 319
Cdd:PRK15127 246 FGKILLKVnQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASgLGIKLATGA-NALDTAAAIRAELAKMEPFFPSGLKIV 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 320 LLGDASAFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGI 399
Cdd:PRK15127 325 YPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGL 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 400 LVDDATVTIENINWHL-EQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFIL 478
Cdd:PRK15127 405 LVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 479 SRTLVPTLAMFLLKPHRpepgAGHHPEDAfinhhegeqhpkprnallqsvLNFQQGFERHFSNVRDTYHGLLTLALGARK 558
Cdd:PRK15127 485 ALILTPALCATMLKPIA----KGDHGEGK---------------------KGFFGWFNRMFEKSTHHYTDSVGNILRSTG 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 559 RFIVGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLGTRIEESAAAFDRIEARIrevipaeeLDTIVDNIGIPLS 638
Cdd:PRK15127 540 RYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYY--------LTKEKNNVESVFA 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 639 GIDMAYSSSGTigpQDGDIQVSLKTHHAPTADYVK------KLREALPQSFPGSHFAF-LPAdissqILNFGAPAPLDVK 711
Cdd:PRK15127 612 VNGFGFAGRGQ---NTGIAFVSLKDWADRPGEENKveaitmRATRAFSQIKDAMVFAFnLPA-----IVELGTATGFDFE 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 712 ISGR----NDAENRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVTNSMVASLAGSsqtapt 787
Cdd:PRK15127 684 LIDQaglgHEKLTQARNQLLGEAAKHPDMLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGS------ 757
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 788 fWLN---PANGVSYSIVAATPQYRLdsLPS-LEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYAN-VQG 862
Cdd:PRK15127 758 -YVNdfiDRGRVKKVYVMSEAKYRM--LPDdIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQaAPG 834
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 863 RDLGgvarDVQKVLDDTASMRPKGATISLHGQidALHEAFSGLSFGLLGAVVLI--YLLIVVNFQSWADPFVIITALPAA 940
Cdd:PRK15127 835 KSTG----EAMELMEELASKLPTGVGYDWTGM--SYQERLSGNQAPALYAISLIvvFLCLAALYESWSIPFSVMLVVPLG 908
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 941 LAGIVWMLFLSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDAL-KAALEAGYTRFRPVCMTALAMIIGMLP 1019
Cdd:PRK15127 909 VIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLiEATLEAVRMRLRPILMTSLAFILGVMP 988
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|....*..
gi 504531890 1020 LAISE-----EQNApLGRAVIGGLVFATVATLLFVPVVFSLVHGRHPTRATAGETPH 1071
Cdd:PRK15127 989 LVISSgagsgAQNA-VGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDIEHSH 1044
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
9-1053 |
3.85e-72 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 260.04 E-value: 3.85e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 9 LHKPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAMAGRVIYTYERSLSTTVNDIEHIESQSLP 88
Cdd:PRK10614 8 IYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 89 GMGIVkIFFQPGVDIRTANAQVTAVSQTVLKQMPPGI-TPPLILNYSASTVPILQMAFSSPSLSEAKIRDLVQNNIRLPL 167
Cdd:PRK10614 88 STRII-LQFDFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 168 SALPGLAMPTPMGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTILLNNSPKAIDELNDLPI 247
Cdd:PRK10614 167 SQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLII 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 248 KTVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDGIRQMLPRINETLPPSLKTSLLGDASAF 327
Cdd:PRK10614 247 HYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPT 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 328 VKQSVGSVAQEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDATVT 407
Cdd:PRK10614 327 IRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 408 IENINWHLEQGKAVKAAILDGAAQiVGPAFVSL-LCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLVPTL 486
Cdd:PRK10614 407 LENISRHLEAGMKPLQAALQGVRE-VGFTVLSMsLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMM 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 487 AMFLLKPHRPepgaghhpedafinhhegEQHPKPRnALLQSVLNFQQGFERHFSNVRDtyHGLLTLALgarkrfivgFLA 566
Cdd:PRK10614 486 CAWLLKSSKP------------------REQKRLR-GFGRMLVALQQGYGRSLKWVLN--HTRWVGVV---------LLG 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 567 CVLASFLLLPSLGQDFFPATDAGALalhvrlpLGTRIEESAAAFDRIEARIREVIPAEELDTIVDNIgIPLSGIDMAYSS 646
Cdd:PRK10614 536 TIALNVWLYISIPKTFFPEQDTGRL-------MGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNV-TGFTGGSRVNSG 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 647 SGTIGPQdgdiqvSLKTHHAPTADYVKKLREALPQSfPGSHFAFLPADissqilnfgapaplDVKISGRND--------- 717
Cdd:PRK10614 608 MMFITLK------PLSERSETAQQVIDRLRVKLAKE-PGANLFLMAVQ--------------DIRVGGRQSnasyqytll 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 718 ----AENRAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRMRANGLGITERDVtNSMVASLAGSSQTAPTFwlNPA 793
Cdd:PRK10614 667 sddlAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAA-NSLLNNAFGQRQISTIY--QPL 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 794 NgvSYSIV-AATPQYRLDsLPSLEALPVTGANGQAQILGGVATISRVQSPAVVTHYNIEPTLDLYANV-QGRDLGGVARD 871
Cdd:PRK10614 744 N--QYKVVmEVDPRYTQD-ISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLpTGKSLSDASAA 820
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 872 VQKVLddTASMRPKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLS 951
Cdd:PRK10614 821 IERAM--TQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELF 898
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 952 GTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHG-DALKAALEAGYTRFRPVCMTALAMIIGMLPLAISE----EQ 1026
Cdd:PRK10614 899 NAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNlTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGgdgaEL 978
|
1050 1060
....*....|....*....|....*..
gi 504531890 1027 NAPLGRAVIGGLVFATVATLLFVPVVF 1053
Cdd:PRK10614 979 RQPLGITIVGGLVMSQLLTLYTTPVVY 1005
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-486 |
4.64e-37 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 151.41 E-value: 4.64e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 3 GLVKTALHKPYTFIVLAIFICIIGPMAALRTPTDVFP--DIGIPVVAVVWQyNGLSPDAMAGRViytyeRSLSTTVNDIE 80
Cdd:COG0841 517 RLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPeeDQGQIIVSVQLP-PGTSLERTEAVV-----RQVEEILLEVP 590
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 81 HIES----------QSLPGMGIVKIFFQPGvDIRTANAQ-VTAVSQTVLKQMpPGIT----PPLILNYSASTvPIlQMAF 145
Cdd:COG0841 591 EVESvfsvvgfsggGSGSNSGTIFVTLKPW-DERDRSADeIIARLREKLAKI-PGARvfvfQPPAGGLGSGA-PI-EVQL 666
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 146 SSPSLSE-AKIRDLVQNNIRlplsALPGLAMPTP-MGGKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKL 223
Cdd:COG0841 667 QGDDLEElAAAAEKLLAALR----QIPGLVDVRSdLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNR 742
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 224 GLNEYTILL---NNSPKAIDELNDLPIKTVDGALITIGQVAHVRDGSPPQTnIVRVDGHRAV-LMPALKNGsISTLSIID 299
Cdd:COG0841 743 GGREYDVRVqapEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSS-INRYNGQRSVtVSANLAPG-VSLGEALA 820
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 300 GIRQMLPRINetLPPSLKTSLLGDASAFvKQSVGSVAQeGIIAALLTSAMILLFL-GSWRSTLIIAASIPLAVLSAIALL 378
Cdd:COG0841 821 AIEELAAELK--LPPGVSIEFTGQAEEE-QESFSSLGL-AFLLALLLVYLVLAAQfESFIQPLIILLTVPLALIGALLGL 896
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 379 AVSGQTLNVMTLGGLALAVGILVDDATVTIENINWHLEQGKAVKAAILDGAAQ------------IVGpafvsllciciv 446
Cdd:COG0841 897 LLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLrlrpilmtslatILG------------ 964
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 504531890 447 FVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLVPTL 486
Cdd:COG0841 965 LLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVL 1004
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
184-498 |
8.36e-14 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 76.34 E-value: 8.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 184 RQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGLNEYTIL------LNNSPKAideLNDLPIKTVDG----- 252
Cdd:TIGR00914 725 PYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVirlpesLRESPQA---LRQLPIPLPLSedark 801
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 253 ALITIGQVAHVRDGSPPqTNIVRVDGHRAVLMPALKNGSiSTLSIIDGIRQmlpRINE--TLPPSLKTS------LLGDA 324
Cdd:TIGR00914 802 QFIPLSDVADLRVSPGP-NQISRENGKRRVVVSANVRGR-DLGSFVDDAKK---AIAEqvKLPPGYWITwggqfeQLQSA 876
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 325 SAFVKQSVGsvaqegiIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDA 404
Cdd:TIGR00914 877 TKRLQIVVP-------VTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNG 949
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 405 TVTIENINWHLEQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSRTLVP 484
Cdd:TIGR00914 950 LVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLP 1029
|
330
....*....|....*
gi 504531890 485 TL-AMFLLKPHRPEP 498
Cdd:TIGR00914 1030 ALyRLVHRRRHKGRK 1044
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
277-1064 |
1.12e-11 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 69.12 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 277 DGHRAVLM----PALKNGSISTLSIIDGIRQMLPRINEtlpPSLKTSLLGDA---SAFVKQSVGSVAQEGIIAALLTSAM 349
Cdd:COG1033 158 DGKATLIVvtldPDPLSSDLDRKEVVAEIRAIIAKYED---PGVEVYLTGFPvlrGDIAEAIQSDLAIFFPLALLLILLL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 350 ILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDATVTIENINWHLEQGKAVKAAILDGA 429
Cdd:COG1033 235 LFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREAL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 430 AQIVGPAFVSLLCICIVFVpMFLLQGIAgyLFRPMALAVIFAMASSFILSRTLVPTLAMFLLKPhrpepgaghhpedafI 509
Cdd:COG1033 315 RKLGPPVLLTSLTTAIGFL-SLLFSDIP--PIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRP---------------K 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 510 NHHEGEQHPKPRNALLQSVLNFqqgferhfsnvrdtyhglltlALGARKRFIVGFLACVLASFLLLPSLGQDFFPATDag 589
Cdd:COG1033 377 PKTRRLKKPPELGRLLAKLARF---------------------VLRRPKVILVVALVLAVVSLYGISRLKVEYDFEDY-- 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 590 alalhvrLPLGTRIEESAAAFDRIearirevipaeeldtivdnigipLSGIDMaysssgtigpqdgdIQVSLKTHHApta 669
Cdd:COG1033 434 -------LPEDSPIRQDLDFIEEN-----------------------FGGSDP--------------LEVVVDTGEP--- 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 670 dyvkklrealpqsfpgshfaflpadissqilnfgapapldvkiSGRNDAENRAYAVELERRLQHVPGIadlriQQSTGYP 749
Cdd:COG1033 467 -------------------------------------------DGLKDPEVLKEIDRLQDYLESLPEV-----GKVLSLA 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 750 SLqvnVDRMRANglgiterdvtnsmvaslagssqtaptfwLNPANGVSYSIvaatPqyrlDSLPSLEALPVTGANGQAQI 829
Cdd:COG1033 499 DL---VKELNQA----------------------------LNEGDPKYYAL----P----ESRELLAQLLLLLSSPPGDD 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 830 LGGVATISRVQSPAVVThynieptldlYANVQGRDLGGVARDVQKVLDDTASmrPKGATISLHGQI----DALHEAFSGL 905
Cdd:COG1033 540 LSRFVDEDYSAARVTVR----------LKDLDSEEIKALVEEVRAFLAENFP--PDGVEVTLTGSAvlfaAINESVIESQ 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 906 SFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSGTSLSVPALTGAILCMGVATANSILVVSFCRERL 985
Cdd:COG1033 608 IRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREER 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 986 AEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPLAISE-EQNAPLGRAVIGGLVFATVATLLFVPVVFSLVHGRHPTRA 1064
Cdd:COG1033 688 RKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSfPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRIAKKR 767
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
909-1072 |
2.39e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 64.88 E-value: 2.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 909 LLGAVVLIYLLIVVNFQSWADPFViitALPAALAGIVWML---FLSGTSLSVPALTGAILCMGVATANSILVVSFCRERL 985
Cdd:COG1033 224 FPLALLLILLLLFLFFRSLRGVLL---PLLVVLLAVIWTLglmGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREER 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 986 AEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPLAISEeqnAPLGR--AVIG--GLVFATVATLLFVPVVFSLVHGRHP 1061
Cdd:COG1033 301 RKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSD---IPPIRdfGIVAaiGVLLAFLTSLTLLPALLSLLPRPKP 377
|
170
....*....|.
gi 504531890 1062 TRATAGETPHV 1072
Cdd:COG1033 378 KTRRLKKPPEL 388
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
857-1059 |
7.57e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 56.70 E-value: 7.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 857 YANVQ--GRDLGGVARDVQKVLDDTASMRPKGATISLHGQI---DALHEAFSG-LSFGLLGAVVLIYLLIVVNFQSWADP 930
Cdd:COG2409 117 LVTVTldGDAGDEAAEAVDALRDAVAAAPAPGLTVYVTGPAalaADLNEAFEEdLGRAELITLPVALVVLLLVFRSLVAA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 931 FV----IITALPAALAGIVWMLFLSGTSLSVPALTgAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPV 1006
Cdd:COG2409 197 LLplltAGLAVGVALGLLALLAAFTDVSSFAPNLL-TMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAV 275
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 504531890 1007 CMTALAMIIGMLPLAISE-EQNAPLGRAVIGGLVFATVATLLFVPVVFSLVHGR 1059
Cdd:COG2409 276 LFSGLTVAIALLGLLLAGlPFLRSMGPAAAIGVAVAVLAALTLLPALLALLGRR 329
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
253-508 |
9.06e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 56.31 E-value: 9.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 253 ALITIGQVAHVRD-GSPPQTNIVRVDGhRAVLMPALKNGSISTLSIiDGIRQMLPRINETLPPSLKTSLLGDA---SAFV 328
Cdd:COG2409 87 RLRADPGVAGVQDpWDDPAAGLVSEDG-KAALVTVTLDGDAGDEAA-EAVDALRDAVAAAPAPGLTVYVTGPAalaADLN 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 329 KQSVGSVAQEGIIAALLTSAMILLFLGSwrstlIIAASIPL-----AVLSAIALLA-------VSGQTLNVMTLGGLALA 396
Cdd:COG2409 165 EAFEEDLGRAELITLPVALVVLLLVFRS-----LVAALLPLltaglAVGVALGLLAllaaftdVSSFAPNLLTMLGLGVG 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 397 V--GILVddatvtienINWH---LEQGKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLLQgiaGYLFRPMALAVIFA 471
Cdd:COG2409 240 IdyALFL---------VSRYreeLRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAG---LPFLRSMGPAAAIG 307
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 504531890 472 MASSFILSRTLVP----TLAMFLLKPHRPEPGAGHHPEDAF 508
Cdd:COG2409 308 VAVAVLAALTLLPallaLLGRRVFWPRRPRRRRAAAPESGF 348
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
868-1059 |
1.33e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.45 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 868 VARDVQKVLDDTASmrPKGATISLHGQIDALHEAFSGL--SFGLLGAVV--LIYLLIVVNFQSWADPFViitALPAALAG 943
Cdd:TIGR00921 156 IYNDVERSLERTNP--PSGKFLDVTGSPAINYDIEREFgkDMGTTMAISgiLVVLVLLLDFKRWWRPLL---PLVIILFG 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 944 IVWML---FLSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMIIGMLPL 1020
Cdd:TIGR00921 231 VAWVLgimGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAAL 310
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 504531890 1021 AISE-EQNAPLGRAVIGGLVFATVATLLFVPVVFSLV-HGR 1059
Cdd:TIGR00921 311 ALSEfPMVSEFGLGLVAGLITAYLLTLLVLPALLQSIdIGR 351
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
869-1059 |
1.36e-05 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 48.44 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 869 ARDVQKVLDDTASmrPKGATISLHG---QIDALHEAFS-GLSFGLLGAVVLIYLLIVVNFQSWADPFVIIT--------- 935
Cdd:pfam03176 106 VAAVRDAVEQAPP--PEGLKAYLTGpaaTVADLRDAGDrDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLtvglslgaa 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 936 -ALPAALAGIVWMlflsGTSLSVPALTGAILcMGVATANSILVVSFCRERLAEHGDALKAALEAGYTRFRPVCMTALAMI 1014
Cdd:pfam03176 184 qGLVAILAHILGI----GLSTFALNLLVVLL-IAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVA 258
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 504531890 1015 IGMLPLAISE-EQNAPLGRAVIGGLVFATVATLLFVPVVFSLVhGR 1059
Cdd:pfam03176 259 IAMLALSFARlPVFAQVGPTIAIGVLVDVLAALTLLPALLALL-GR 303
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
341-402 |
2.01e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 45.61 E-value: 2.01e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504531890 341 IAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVD 402
Cdd:COG4258 647 LALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGID 708
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
854-1055 |
2.59e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 45.21 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 854 LDLYANVQGRDLGGVARDVQKVLDDTASMR-PKGATISLHGQIDALHEAFSGLSFGLLGAVVLIYLLIV-VNFQSWADPF 931
Cdd:TIGR00921 513 IKVAVIQVQLKQGEPKVQGRKILRDVQHEHpPPGVKVGVTGLPVAFAEMHELVNEGMRRMTIAGAILVLmILLAVFRNPI 592
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 932 VIITALPAALAGIVWM---LFLSGTSLSVPALTGAILCMGVATANSILVVSFCRERLAEHG--DALKAALEAGYTrfrPV 1006
Cdd:TIGR00921 593 KAVFPLIAIGSGILWAiglMGLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEERKEHGpkEAITHTMERTGP---GI 669
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 504531890 1007 CMTALAMIIGMLPLAISEE---QNapLGRAVIGGLVFATVATLLFVPVVFSL 1055
Cdd:TIGR00921 670 LFSGLTTAGGFLSLLLSHFpimRN--FGLVQGIGVLSSLTAALVVFPALLVL 719
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
325-428 |
4.11e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 44.45 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 325 SAFVKQSVGSVA-QEGIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGqtLN-VMTLGGLA---LAVGI 399
Cdd:PRK13024 253 SRSVGPTLGQDAiDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSS--LGaVLTLPGIAglvLGIGM 330
|
90 100 110
....*....|....*....|....*....|
gi 504531890 400 LVdDATVTI-ENINWHLEQGKAVKAAILDG 428
Cdd:PRK13024 331 AV-DANVLIfERIKEELRKGKSLKKAFKKG 359
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
339-483 |
3.11e-03 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 41.12 E-value: 3.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 339 GIIAALLTSAMILLFLGSWRSTLIIAASIPLaVLSAIALLAVSGQTLNVMTLGGLA---LAVGILVDDATVTIENINWHL 415
Cdd:TIGR01129 250 GIKAGLIGLVLVLVFMILYYRLFGLIAAIAL-VINIVLILAILSAFGATLTLPGIAgliLTIGMAVDANVLIYERIKEEL 328
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504531890 416 EQGKAVKAAILDG----AAQIVGPAFVSLLCICIVFVpmFLLQGIAGYLFrPMALAVIFAMASSFILSRTLV 483
Cdd:TIGR01129 329 RLGKSVRQAIEAGferaFSTIFDANITTLIAALILYV--FGTGPVKGFAV-TLAIGIIASLFTALVFTRLLL 397
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
339-483 |
4.10e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 41.24 E-value: 4.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 339 GIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLsaIALLAVSGQTLNVMTLGGLALAVGILVDDATVTIENINWHLEQG 418
Cdd:PRK14726 378 GLIAAILVAALMIGFYGFLGVIAVIALIVNVVLI--IAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTG 455
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 419 KAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFLL-----QGIAGYLfrpmALAVIFAMASSFILSRTLV 483
Cdd:PRK14726 456 HSLIQALDRGFSRALATIVDANVTILIAAVILFFLgsgavRGFAVTL----AVGILTTVFTAFTLTRSLV 521
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
339-500 |
5.92e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 40.61 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 339 GIIAALLTSAMILLFLGSWRSTLIIAASIPLAVLSAIALLAVSGQTLNVMTLG-GLALaVGILVDDAtvtienINWHLEQ 417
Cdd:COG4258 255 GLISLLGILLLLLLVFRSLRPLLLGLLPVAVGALAGLAAVSLVFGSVHGITLGfGSSL-IGVAVDYS------LHYLTHR 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504531890 418 GKAVKAAILDGAAQIVGPAFVSLLCICIVFVPMFL--LQGiagylFRPMALAVIFAMASSFILSRTLVPTLAMFLLKPHR 495
Cdd:COG4258 328 RAAGEWDPRAALRRIWPTLLLGLLTTVLGYLALLFspFPG-----LRQLGVFAAAGLLAAALTTLLWLPLLLPRAAPRPP 402
|
....*
gi 504531890 496 PEPGA 500
Cdd:COG4258 403 APALA 407
|
|
| |
