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Conserved domains on  [gi|504436460|ref|WP_014623562|]
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isoprenyl transferase [Streptococcus equi]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10794083)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 1-249 6.64e-180

undecaprenyl pyrophosphate synthase; Provisional


:

Pssm-ID: 184840  Cd Length: 251  Bit Score: 493.62  E-value: 6.64e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   1 MFGLKAKSKK------IVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENW 74
Cdd:PRK14830   1 MFKFFKKKKKtsfdeeLDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  75 SRPQDEVSFIMNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAV 154
Cdd:PRK14830  81 KRPKDEVKFLMNLPVEFLDKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 155 GLIAQDVLDAKLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLK 234
Cdd:PRK14830 161 KEIAKDVLDGKLNPEDITEELISNYLMTKGLP----DPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLK 236

                        250
                 ....*....|....*
gi 504436460 235 AIEDYNHRHRRFGAI 249
Cdd:PRK14830 237 AIKDYQSRQRRFGGV 251
 
Name Accession Description Interval E-value
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 1-249 6.64e-180

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 493.62  E-value: 6.64e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   1 MFGLKAKSKK------IVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENW 74
Cdd:PRK14830   1 MFKFFKKKKKtsfdeeLDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  75 SRPQDEVSFIMNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAV 154
Cdd:PRK14830  81 KRPKDEVKFLMNLPVEFLDKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 155 GLIAQDVLDAKLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLK 234
Cdd:PRK14830 161 KEIAKDVLDGKLNPEDITEELISNYLMTKGLP----DPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLK 236

                        250
                 ....*....|....*
gi 504436460 235 AIEDYNHRHRRFGAI 249
Cdd:PRK14830 237 AIKDYQSRQRRFGGV 251
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
5-249 8.69e-160

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 442.57  E-value: 8.69e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   5 KAKSKKIVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFI 84
Cdd:COG0020    4 RALLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  85 MNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDA 164
Cdd:COG0020   84 MGLLREYLRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 165 KLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHR 244
Cdd:COG0020  164 ELDPEDIDEETISRYLYTADLP----DPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRER 239


                 ....*
gi 504436460 245 RFGAI 249
Cdd:COG0020  240 RFGGT 244
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 19-241 1.38e-140

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 392.89  E-value: 1.38e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  19 HIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPE 98
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  99 LHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDLIAN 178
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504436460 179 YLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNH 241
Cdd:cd00475  161 HLYTADLP----DPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 23-247 2.43e-140

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 392.50  E-value: 2.43e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   23 IMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVE-FFDKYVPELHK 101
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  102 NNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVldAKLNPGDITEDLIANYLM 181
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEG--KKLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504436460  182 TDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:pfam01255 159 TAGLP----DPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 18-247 1.12e-99

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 289.69  E-value: 1.12e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   18 KHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVP 97
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   98 ELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDLIA 177
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  178 NYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:TIGR00055 161 KHLYTANLP----PVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 1-249 6.64e-180

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 493.62  E-value: 6.64e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   1 MFGLKAKSKK------IVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENW 74
Cdd:PRK14830   1 MFKFFKKKKKtsfdeeLDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  75 SRPQDEVSFIMNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAV 154
Cdd:PRK14830  81 KRPKDEVKFLMNLPVEFLDKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 155 GLIAQDVLDAKLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLK 234
Cdd:PRK14830 161 KEIAKDVLDGKLNPEDITEELISNYLMTKGLP----DPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLK 236

                        250
                 ....*....|....*
gi 504436460 235 AIEDYNHRHRRFGAI 249
Cdd:PRK14830 237 AIKDYQSRQRRFGGV 251
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
5-249 8.69e-160

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 442.57  E-value: 8.69e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   5 KAKSKKIVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFI 84
Cdd:COG0020    4 RALLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  85 MNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDA 164
Cdd:COG0020   84 MGLLREYLRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 165 KLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHR 244
Cdd:COG0020  164 ELDPEDIDEETISRYLYTADLP----DPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRER 239


                 ....*
gi 504436460 245 RFGAI 249
Cdd:COG0020  240 RFGGT 244
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 19-241 1.38e-140

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 392.89  E-value: 1.38e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  19 HIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPE 98
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  99 LHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDLIAN 178
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504436460 179 YLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNH 241
Cdd:cd00475  161 HLYTADLP----DPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 23-247 2.43e-140

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 392.50  E-value: 2.43e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   23 IMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVE-FFDKYVPELHK 101
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  102 NNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVldAKLNPGDITEDLIANYLM 181
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEG--KKLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504436460  182 TDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:pfam01255 159 TAGLP----DPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 16-247 7.79e-109

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 313.93  E-value: 7.79e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  16 VPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKY 95
Cdd:PRK14836  14 IPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKALDRE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  96 VPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDL 175
Cdd:PRK14836  94 VDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEIDEAL 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504436460 176 IANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:PRK14836 174 LAQHLALADLP----EPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFG 241
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 14-249 2.47e-105

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 304.95  E-value: 2.47e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  14 DRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFD 93
Cdd:PRK14831  18 QRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERVLR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  94 KYVPELHKNNVKVQMIGETNRLPKdTLKAL-EAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDIT 172
Cdd:PRK14831  98 RELEELMEENVRIRFVGDLDPLPK-SLQEEiSRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEID 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504436460 173 EDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFGAI 249
Cdd:PRK14831 177 ENLFESELYTAGIK----DPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGGV 249
PRK14834 PRK14834
isoprenyl transferase;
16-247 1.73e-101

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 295.12  E-value: 1.73e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  16 VPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKY 95
Cdd:PRK14834  14 VPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFIRRD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  96 VPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDL 175
Cdd:PRK14834  94 LAELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPASIDAET 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504436460 176 IANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:PRK14834 174 ISANLDTADIP----DPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 18-247 1.12e-99

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 289.69  E-value: 1.12e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   18 KHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVP 97
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   98 ELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDLIA 177
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  178 NYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:TIGR00055 161 KHLYTANLP----PVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14838 PRK14838
isoprenyl transferase;
9-247 5.01e-94

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 275.98  E-value: 5.01e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   9 KKIVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLP 88
Cdd:PRK14838   3 EQIDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  89 VEFFDKYVpeLHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNP 168
Cdd:PRK14838  83 LDSIEEET--FMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNP 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504436460 169 GDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:PRK14838 161 EEITEESISEHLTTNFMP----DPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFG 235
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 15-249 4.08e-84

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 251.46  E-value: 4.08e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  15 RVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDK 94
Cdd:PRK14832  17 KIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLLRR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  95 YVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITED 174
Cdd:PRK14832  97 ELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVNEQ 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504436460 175 LIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFGAI 249
Cdd:PRK14832 177 LVEQHLYTADTP----PPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQV 247
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 16-249 5.71e-84

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 250.47  E-value: 5.71e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  16 VPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKY 95
Cdd:PRK14829  14 LPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVIHRR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  96 VPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDL 175
Cdd:PRK14829  94 REQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISGDRVTEKM 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504436460 176 IANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFGAI 249
Cdd:PRK14829 174 ISDHLYNPDMP----DVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGGV 243
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
17-249 3.94e-82

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 245.49  E-value: 3.94e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  17 PKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYV 96
Cdd:PRK14833   5 LKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLKDER 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  97 PELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVgliaQDVLDAKLNPG---DITE 173
Cdd:PRK14833  85 STYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAF----KKLLESPPSHIgelESLE 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504436460 174 DLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFGAI 249
Cdd:PRK14833 161 EEISNCLDTADLP----EVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFGGL 232
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 5-248 1.04e-77

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 236.39  E-value: 1.04e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   5 KAKSKKIVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFI 84
Cdd:PRK14827  56 KAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFL 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  85 MNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDA 164
Cdd:PRK14827 136 MGFNRDVVRRRRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAG 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 165 KLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHR 244
Cdd:PRK14827 216 RLNPERITESTIARHLQRPDIP----DVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNR 291


                 ....
gi 504436460 245 RFGA 248
Cdd:PRK14827 292 RFGS 295
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 5-247 2.06e-77

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 234.35  E-value: 2.06e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460   5 KAKSKKIVLDRVPKHIGIIMDGNGRWAKK----RLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDE 80
Cdd:PRK14840   7 QAQENFPSLQSLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  81 VSFIMNLPVEFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD 160
Cdd:PRK14840  87 VAELFSLFNSQLDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQD 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 161 VLDAKLNPGDITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYN 240
Cdd:PRK14840 167 LANKKISSDDISEELISSYLDTSGLP----DPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQ 242


                 ....*..
gi 504436460 241 HRHRRFG 247
Cdd:PRK14840 243 QRSRRGG 249
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 15-249 4.26e-77

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 232.96  E-value: 4.26e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  15 RVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDK 94
Cdd:PRK14841   2 RIPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  95 YVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKlnPGDITED 174
Cdd:PRK14841  82 EMELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQGK--KIELTEE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504436460 175 LIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFGAI 249
Cdd:PRK14841 160 TFRQYLYLPDVP----DPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFGGL 230
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
24-247 4.14e-76

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 230.26  E-value: 4.14e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  24 MDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKNN 103
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 104 VKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPGDITEDLIANYLMTD 183
Cdd:PRK10240  81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHICMH 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504436460 184 HLPYLyrdpDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:PRK10240 161 ELAPV----DLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFG 220
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 10-249 2.93e-71

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 218.32  E-value: 2.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  10 KIVLDRVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPV 89
Cdd:PRK14842   2 GLFESTIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  90 EFFDKYVPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAvgliAQDVLDAKLNPG 169
Cdd:PRK14842  82 EFIETRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRA----AQEVFLARKAKK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 170 D-----ITEDLIANYLMTDHLPYLyrdpDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHR 244
Cdd:PRK14842 158 VtlekpLKEKEFEKFLYTSPLPPV----DLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTR 233


                 ....*
gi 504436460 245 RFGAI 249
Cdd:PRK14842 234 KFGGL 238
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 11-248 6.18e-71

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 217.69  E-value: 6.18e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  11 IVLDRVPKHIGIIMDGNGRWAKKRLKPRVF-GHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPV 89
Cdd:PRK14828  21 LDGAQVPGHVGIIVDGNRRWARKAGFTDVSqGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLDIIE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  90 EFFDKYVPElhkNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNPG 169
Cdd:PRK14828 101 DVVRQLAPD---GRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKGTSID 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 170 D----ITEDLIANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRR 245
Cdd:PRK14828 178 ElaesVTVDAISTHLYTGGQP----DPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERR 253


                 ...
gi 504436460 246 FGA 248
Cdd:PRK14828 254 FGK 256
PRK14835 PRK14835
isoprenyl transferase;
15-247 2.33e-69

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 214.71  E-value: 2.33e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  15 RVPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLpvefFDK 94
Cdd:PRK14835  40 KLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNL----FER 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  95 YV------PELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQDVLDAKLNP 168
Cdd:PRK14835 116 EArrmavdPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKSP 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 169 GDITEDL----IANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHR 244
Cdd:PRK14835 196 EEVAAELtpehISAHLYTAGVP----DPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRER 271


                 ...
gi 504436460 245 RFG 247
Cdd:PRK14835 272 RFG 274
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
19-249 4.43e-68

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 210.00  E-value: 4.43e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  19 HIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPE 98
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETER 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  99 LHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGliaqdvldAKLNPGDITEDLIAN 178
Cdd:PRK14839  92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAA--------KALGPEGLSREAFSD 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504436460 179 YLMTDHlpylyRDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFGAI 249
Cdd:PRK14839 164 LLTGDG-----GDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFGGL 229
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 16-247 1.84e-52

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 170.00  E-value: 1.84e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  16 VPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKY 95
Cdd:PRK14837   6 LPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYLSSE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  96 VPELHKNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVgliaQDVLDAKLNPGDITEDL 175
Cdd:PRK14837  86 FNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAV----KKFLSSGLDLETLNENV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504436460 176 IANYLMTDHLPylyrDPDLIIRTSGELRLSNFMPWQSAYSELYFTPVLWPDFKRAELLKAIEDYNHRHRRFG 247
Cdd:PRK14837 162 FSKFLDNPELP----DLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFG 229
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 18-239 2.98e-24

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 98.53  E-value: 2.98e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  18 KHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFI--MNLPV----EF 91
Cdd:PTZ00349  21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLfyLNLLIlineDF 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460  92 FDKYVPElhkNNVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEI--------------------- 150
Cdd:PTZ00349 101 FFKFIKD---NKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMslckfnpnlyfdtyknlleek 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436460 151 -----TNAVGLIAQ-------------DVLDAKLNPGDITEDL--------------------IANY---LMTDHLPyly 189
Cdd:PTZ00349 178 kilcgSNILTDPIKegtfaipddedecDYLDHELENERIDLDLkfdgdcicgeksflneeqieIVNYhkkLLTSDLP--- 254

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 504436460 190 rDPDLIIRTSGELRLSNFMPWQ-SAYSELYFTPVLWPDFKRAELLKAIEDY 239
Cdd:PTZ00349 255 -PPNILIRTSGEKRLSDFMLYQiSEFTEIYFINEYWPIFNFLQFIYIILHY 304
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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