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Conserved domains on  [gi|504436442|ref|WP_014623544|]
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Rep family protein [Streptococcus equi]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA_helicase super family cl46641
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 246-342 2.94e-07

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


The actual alignment was detected with superfamily member pfam00910:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 48.37  E-value: 2.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436442  246 LFITAESGVGKTHYSKQLIALLQNiALKHGQIWDYCVTASTNAFDEYNGQEILFLDDVKGNSLTV--SDWLKLLDPYMIS 323
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLARALLK-KLGLPKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNPDGPdeAELIRLVSSTPYP 79

                          90       100
                  ....*....|....*....|.
gi 504436442  324 PISAR--YHNKMGSAKVIIIT 342
Cdd:pfam00910  80 PPMAAleEKGTPFTSKFVIVT 100
Rep_2 super family cl03327
Plasmid replication protein; This family consists of various bacterial plasmid replication ...
 65-158 1.68e-05

Plasmid replication protein; This family consists of various bacterial plasmid replication (Rep) proteins. These proteins are essential for replication of plasmids, the Rep proteins are topoisomerases that nick the positive stand at the plus origin of replication and also at the single-strand conversion sequence.


The actual alignment was detected with superfamily member pfam01719:

Pssm-ID: 396331  Cd Length: 181  Bit Score: 45.22  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436442   65 HDKDKvsvwDSEKmkniiENKTEHIHALLKFEKGASLTKIALAI-----GVEPQFLEKLksgrygyDNCLAYLVHAKDES 139
Cdd:pfam01719  39 HDKDL----NVNG-----ELKKAHYHIILIFKNPKTIEQIANKLkdalgGVQVEFIESI-------RNAYSYLIHETNPE 102

                          90
                  ....*....|....*....
gi 504436442  140 KHQYQPDEVVTVKGEDYTS 158
Cdd:pfam01719 103 KHQYSISDIETFNGFDIDK 121
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 246-342 2.94e-07

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 48.37  E-value: 2.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436442  246 LFITAESGVGKTHYSKQLIALLQNiALKHGQIWDYCVTASTNAFDEYNGQEILFLDDVKGNSLTV--SDWLKLLDPYMIS 323
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLARALLK-KLGLPKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNPDGPdeAELIRLVSSTPYP 79

                          90       100
                  ....*....|....*....|.
gi 504436442  324 PISAR--YHNKMGSAKVIIIT 342
Cdd:pfam00910  80 PPMAAleEKGTPFTSKFVIVT 100
Rep_2 pfam01719
Plasmid replication protein; This family consists of various bacterial plasmid replication ...
 65-158 1.68e-05

Plasmid replication protein; This family consists of various bacterial plasmid replication (Rep) proteins. These proteins are essential for replication of plasmids, the Rep proteins are topoisomerases that nick the positive stand at the plus origin of replication and also at the single-strand conversion sequence.


Pssm-ID: 396331  Cd Length: 181  Bit Score: 45.22  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436442   65 HDKDKvsvwDSEKmkniiENKTEHIHALLKFEKGASLTKIALAI-----GVEPQFLEKLksgrygyDNCLAYLVHAKDES 139
Cdd:pfam01719  39 HDKDL----NVNG-----ELKKAHYHIILIFKNPKTIEQIANKLkdalgGVQVEFIESI-------RNAYSYLIHETNPE 102

                          90
                  ....*....|....*....
gi 504436442  140 KHQYQPDEVVTVKGEDYTS 158
Cdd:pfam01719 103 KHQYSISDIETFNGFDIDK 121
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 246-342 2.94e-07

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 48.37  E-value: 2.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436442  246 LFITAESGVGKTHYSKQLIALLQNiALKHGQIWDYCVTASTNAFDEYNGQEILFLDDVKGNSLTV--SDWLKLLDPYMIS 323
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLARALLK-KLGLPKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNPDGPdeAELIRLVSSTPYP 79

                          90       100
                  ....*....|....*....|.
gi 504436442  324 PISAR--YHNKMGSAKVIIIT 342
Cdd:pfam00910  80 PPMAAleEKGTPFTSKFVIVT 100
Rep_2 pfam01719
Plasmid replication protein; This family consists of various bacterial plasmid replication ...
 65-158 1.68e-05

Plasmid replication protein; This family consists of various bacterial plasmid replication (Rep) proteins. These proteins are essential for replication of plasmids, the Rep proteins are topoisomerases that nick the positive stand at the plus origin of replication and also at the single-strand conversion sequence.


Pssm-ID: 396331  Cd Length: 181  Bit Score: 45.22  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504436442   65 HDKDKvsvwDSEKmkniiENKTEHIHALLKFEKGASLTKIALAI-----GVEPQFLEKLksgrygyDNCLAYLVHAKDES 139
Cdd:pfam01719  39 HDKDL----NVNG-----ELKKAHYHIILIFKNPKTIEQIANKLkdalgGVQVEFIESI-------RNAYSYLIHETNPE 102

                          90
                  ....*....|....*....
gi 504436442  140 KHQYQPDEVVTVKGEDYTS 158
Cdd:pfam01719 103 KHQYSISDIETFNGFDIDK 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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