|
Name |
Accession |
Description |
Interval |
E-value |
| trans_reg_YgbI |
NF040890 |
DNA-binding transcriptional repressor YgbI; |
1-253 |
1.64e-145 |
|
DNA-binding transcriptional repressor YgbI;
Pssm-ID: 468826 [Multi-domain] Cd Length: 253 Bit Score: 407.30 E-value: 1.64e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRSANRLASEPSHLTKTALFNEEKK 80
Cdd:NF040890 1 MIPVERHQQILALVAERGVVSIAELTERLGVSHMTIRRDLQKLEQQGAVLSVSGGVQSPERLAQEPSHQDKEAMASRQKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 81 AIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARH 160
Cdd:NF040890 81 AIGQLAAQQIPPNSCIYLDAGTTTLALARHLAERQDLTVVTNDFVIADYLIENSQCTIIHTGGAVCRENRSCVGEAAAQA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 161 LRQLAIDIAFVSTSSWGLRGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGRN 240
Cdd:NF040890 161 LRNLFIDIAFISASSWSMRGLSTPSEDKVAVKRAIVEASRQRVLLCDTSKYGKIATYLALPMTVFDTIITDDGLPEAAKE 240
|
250
....*....|...
gi 504406949 241 ALQAGSWELMMAG 253
Cdd:NF040890 241 ALEKAGISLLLAK 253
|
|
| GlpR |
COG1349 |
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ... |
1-253 |
7.44e-98 |
|
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];
Pssm-ID: 440960 [Multi-domain] Cd Length: 254 Bit Score: 286.26 E-value: 7.44e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRSANRLASEPSHLTKTALFNEEKK 80
Cdd:COG1349 1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 81 AIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARH 160
Cdd:COG1349 81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 161 LRQLAIDIAFVSTSSWGL-RGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGR 239
Cdd:COG1349 161 LRRFRADKAFLGASGIDAeGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELL 240
|
250
....*....|....
gi 504406949 240 NALQAGSWELMMAG 253
Cdd:COG1349 241 EALEEAGVEVIVAE 254
|
|
| DeoRC |
pfam00455 |
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ... |
77-231 |
1.07e-65 |
|
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395365 Cd Length: 160 Bit Score: 201.20 E-value: 1.07e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 77 EEKKAIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDA 156
Cdd:pfam00455 4 EEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGPL 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504406949 157 AARHLRQLAIDIAFVSTSSWGL-RGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTD 231
Cdd:pfam00455 84 AEEFLRQFNVDKAFIGANGIDLeGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITD 159
|
|
| PRK09802 |
PRK09802 |
DeoR family transcriptional regulator; |
5-253 |
2.80e-44 |
|
DeoR family transcriptional regulator;
Pssm-ID: 182086 [Multi-domain] Cd Length: 269 Bit Score: 150.39 E-value: 2.80e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 5 ERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGG--VRSANRLASEPSHLTKTALFNEEKKAI 82
Cdd:PRK09802 17 ERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGalICDSTTPSVEPSVEDKSALNTAMKRSV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 83 GKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARHLR 162
Cdd:PRK09802 97 AKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQ 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 163 QLAIDIAFVSTSSWGL-RGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGRNA 241
Cdd:PRK09802 177 NYHFDMLFLGVDAIDLeRGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEG 256
|
250
....*....|..
gi 504406949 242 LQAGSWELMMAG 253
Cdd:PRK09802 257 LRKAGVEVILVG 268
|
|
| HTH_DEOR |
smart00420 |
helix_turn_helix, Deoxyribose operon repressor; |
6-58 |
6.57e-20 |
|
helix_turn_helix, Deoxyribose operon repressor;
Pssm-ID: 197714 [Multi-domain] Cd Length: 53 Bit Score: 80.34 E-value: 6.57e-20
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 504406949 6 RHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRS 58
Cdd:smart00420 1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
21-54 |
2.34e-04 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 38.58 E-value: 2.34e-04
10 20 30
....*....|....*....|....*....|....
gi 504406949 21 SINELTERFGVSHMTIRRDVQKLEEQGAVLSVSG 54
Cdd:cd07377 27 SERELAEELGVSRTTVREALRELEAEGLVERRPG 60
|
|
| cas_HTH |
TIGR01884 |
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ... |
9-54 |
6.27e-03 |
|
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]
Pssm-ID: 273852 [Multi-domain] Cd Length: 203 Bit Score: 36.95 E-value: 6.27e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 504406949 9 QILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSG 54
Cdd:TIGR01884 147 KILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVEQKGR 192
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| trans_reg_YgbI |
NF040890 |
DNA-binding transcriptional repressor YgbI; |
1-253 |
1.64e-145 |
|
DNA-binding transcriptional repressor YgbI;
Pssm-ID: 468826 [Multi-domain] Cd Length: 253 Bit Score: 407.30 E-value: 1.64e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRSANRLASEPSHLTKTALFNEEKK 80
Cdd:NF040890 1 MIPVERHQQILALVAERGVVSIAELTERLGVSHMTIRRDLQKLEQQGAVLSVSGGVQSPERLAQEPSHQDKEAMASRQKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 81 AIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARH 160
Cdd:NF040890 81 AIGQLAAQQIPPNSCIYLDAGTTTLALARHLAERQDLTVVTNDFVIADYLIENSQCTIIHTGGAVCRENRSCVGEAAAQA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 161 LRQLAIDIAFVSTSSWGLRGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGRN 240
Cdd:NF040890 161 LRNLFIDIAFISASSWSMRGLSTPSEDKVAVKRAIVEASRQRVLLCDTSKYGKIATYLALPMTVFDTIITDDGLPEAAKE 240
|
250
....*....|...
gi 504406949 241 ALQAGSWELMMAG 253
Cdd:NF040890 241 ALEKAGISLLLAK 253
|
|
| GlpR |
COG1349 |
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ... |
1-253 |
7.44e-98 |
|
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];
Pssm-ID: 440960 [Multi-domain] Cd Length: 254 Bit Score: 286.26 E-value: 7.44e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRSANRLASEPSHLTKTALFNEEKK 80
Cdd:COG1349 1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 81 AIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARH 160
Cdd:COG1349 81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 161 LRQLAIDIAFVSTSSWGL-RGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGR 239
Cdd:COG1349 161 LRRFRADKAFLGASGIDAeGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELL 240
|
250
....*....|....
gi 504406949 240 NALQAGSWELMMAG 253
Cdd:COG1349 241 EALEEAGVEVIVAE 254
|
|
| DeoRC |
pfam00455 |
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ... |
77-231 |
1.07e-65 |
|
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395365 Cd Length: 160 Bit Score: 201.20 E-value: 1.07e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 77 EEKKAIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDA 156
Cdd:pfam00455 4 EEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGPL 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504406949 157 AARHLRQLAIDIAFVSTSSWGL-RGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTD 231
Cdd:pfam00455 84 AEEFLRQFNVDKAFIGANGIDLeGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITD 159
|
|
| PRK09802 |
PRK09802 |
DeoR family transcriptional regulator; |
5-253 |
2.80e-44 |
|
DeoR family transcriptional regulator;
Pssm-ID: 182086 [Multi-domain] Cd Length: 269 Bit Score: 150.39 E-value: 2.80e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 5 ERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGG--VRSANRLASEPSHLTKTALFNEEKKAI 82
Cdd:PRK09802 17 ERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGalICDSTTPSVEPSVEDKSALNTAMKRSV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 83 GKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARHLR 162
Cdd:PRK09802 97 AKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQ 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 163 QLAIDIAFVSTSSWGL-RGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGRNA 241
Cdd:PRK09802 177 NYHFDMLFLGVDAIDLeRGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEG 256
|
250
....*....|..
gi 504406949 242 LQAGSWELMMAG 253
Cdd:PRK09802 257 LRKAGVEVILVG 268
|
|
| srlR |
PRK10434 |
DNA-binding transcriptional repressor; |
1-256 |
3.83e-40 |
|
DNA-binding transcriptional repressor;
Pssm-ID: 182457 [Multi-domain] Cd Length: 256 Bit Score: 139.05 E-value: 3.83e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVrSANRLASEPSHLTKTALFNEEKK 80
Cdd:PRK10434 1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGV-VLNKEESDPPIDHKTLINTHKKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 81 AIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVI-HTGGTVCRDNRSCIGDAAAR 159
Cdd:PRK10434 80 LIAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTIlMPGGTFRKKSASFHGQLAEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 160 HLRQLAIDIAFVSTSSWGLR-GLFTPDEdKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAG 238
Cdd:PRK10434 160 AFEHFTFDKLFIGTDGIDLNaGVTTFNE-VYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAF 238
|
250
....*....|....*...
gi 504406949 239 RNALQAGSWELMMAGKSE 256
Cdd:PRK10434 239 RQALEEKGIEVIITGESN 256
|
|
| PRK13509 |
PRK13509 |
HTH-type transcriptional regulator UlaR; |
1-252 |
7.25e-33 |
|
HTH-type transcriptional regulator UlaR;
Pssm-ID: 184100 [Multi-domain] Cd Length: 251 Bit Score: 120.11 E-value: 7.25e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVR--SANRLASEP--SHLTKTAlfn 76
Cdd:PRK13509 1 MTEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAEaiTQQRPRWTPmnIHQAQNH--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 77 EEKKAIGKLAAQLIPPDSCIYLDAGTTTLALAREIADReDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRdNRSCIGDA 156
Cdd:PRK13509 78 DEKVRIAKAASQLCNPGESVVINCGSTAFLLGRELCGK-PVQIITNYLPLANYLIDQEHDSVIIMGGQYNK-SQSITLSP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 157 AARHLRQLAIDIAFVSTSSWGLRGLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNA 236
Cdd:PRK13509 156 QGSENSLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNADP 235
|
250
....*....|....*.
gi 504406949 237 AGRNALQAGSWELMMA 252
Cdd:PRK13509 236 EVLQQLEAQGVSILLV 251
|
|
| PRK10906 |
PRK10906 |
DeoR/GlpR family transcriptional regulator; |
1-231 |
1.11e-28 |
|
DeoR/GlpR family transcriptional regulator;
Pssm-ID: 182827 [Multi-domain] Cd Length: 252 Bit Score: 109.18 E-value: 1.11e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRSANRLASEPSHLTKtALFNEEKK 80
Cdd:PRK10906 1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAALPSSSVNTPWHDRK-ATQTEEKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 81 AIGKLAAQLIPPDSCIYLDAGTTTLALAREIADREDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARH 160
Cdd:PRK10906 80 RIARKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDF 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504406949 161 LRQLAIDIAFVSTSSWGLRG-LFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTD 231
Cdd:PRK10906 160 ISQFRLDFGILGISGIDSDGsLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTD 231
|
|
| PRK10681 |
PRK10681 |
DNA-binding transcriptional repressor DeoR; Provisional |
30-250 |
8.54e-24 |
|
DNA-binding transcriptional repressor DeoR; Provisional
Pssm-ID: 182644 [Multi-domain] Cd Length: 252 Bit Score: 96.30 E-value: 8.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 30 GVSHMTIRRDVQKleEQGAVLSVSGGV----RSANR-LASEpshlTKTALFnEEKKAIGKLAAQLIPPDSCIYLDAGTTT 104
Cdd:PRK10681 32 GVSEMTIRRDLNA--HSAPVVLLGGYIvlepRSASHyLLSD----QKSRLV-EEKRRAAQLAATLVEPNQTLFFDCGTTT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 105 LALAREIADRedlLVVT------NDFMVtnlLMEASRCRVIHTGGTVCRDNrsCIGDAAARH--LRQLAIDIAFVSTSSW 176
Cdd:PRK10681 105 PWIIEAIDNE---LPFTavcyslNTFLA---LQEKPHCRAILCGGEFHASN--AIFKPLDFQqtLDNICPDIAFYSAAGV 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504406949 177 GLR-GLFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDKIATWLALPLEKFDVIVTDDQLNAAGRNALQAGSWELM 250
Cdd:PRK10681 177 HVSkGATCFNLEELPVKHWAMAMAQKHVLVVDHSKFGKVRPARMGDLTRFDTVVSDRCPDDEFVKYAQAQRIKLM 251
|
|
| HTH_DEOR |
smart00420 |
helix_turn_helix, Deoxyribose operon repressor; |
6-58 |
6.57e-20 |
|
helix_turn_helix, Deoxyribose operon repressor;
Pssm-ID: 197714 [Multi-domain] Cd Length: 53 Bit Score: 80.34 E-value: 6.57e-20
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 504406949 6 RHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRS 58
Cdd:smart00420 1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
|
|
| PRK10411 |
PRK10411 |
L-fucose operon activator; |
5-213 |
3.60e-16 |
|
L-fucose operon activator;
Pssm-ID: 236684 [Multi-domain] Cd Length: 240 Bit Score: 75.23 E-value: 3.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 5 ERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSG---GVRSANRLASEPSHLTKTALFNeEKKA 81
Cdd:PRK10411 4 ARQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGrakYIHRQNQDSGDPFHIRLKSHYA-HKAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 82 IGKLAAQLIPPDSCIYLDAGTTTLALAREIADReDLLVVTNDFMVTNLLMEASRCRVIHTGGTVCRDNRSCIGDAAARHL 161
Cdd:PRK10411 83 IAREALAWIEEGMVIALDASSTCWYLARQLPDI-NIQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSLISQL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 504406949 162 RQLAIDIAFVSTSSWGLRG-LFTPDEDKVAVKQAVCEVSSKRILLSDSSKYDK 213
Cdd:PRK10411 162 KSLEIDLFIFSCEGIDSSGaLWDSNAINADYKSMLLKRAAQSLLLIDKSKFNR 214
|
|
| HTH_DeoR |
pfam08220 |
DeoR-like helix-turn-helix domain; |
6-61 |
5.17e-16 |
|
DeoR-like helix-turn-helix domain;
Pssm-ID: 285436 [Multi-domain] Cd Length: 57 Bit Score: 69.98 E-value: 5.17e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 504406949 6 RHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVRSANR 61
Cdd:pfam08220 1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNSS 56
|
|
| YobV |
COG2378 |
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ... |
1-70 |
6.43e-07 |
|
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];
Pssm-ID: 441945 [Multi-domain] Cd Length: 314 Bit Score: 49.31 E-value: 6.43e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504406949 1 MIPVERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVL----SVSGGVRSANRLASEPSHLT 70
Cdd:COG2378 1 MSRLERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELGVPIeaerGRGGGYRLRDGYRLPPLMLT 74
|
|
| HTH_11 |
pfam08279 |
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins. |
8-54 |
1.65e-06 |
|
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
Pssm-ID: 429896 [Multi-domain] Cd Length: 52 Bit Score: 43.96 E-value: 1.65e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 504406949 8 QQILA-LVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGA-VLSVSG 54
Cdd:pfam08279 1 LQILQlLLEARGPISGQELAEKLGVSRRTIRRDIKILEELGVpIEAEPG 49
|
|
| COG3177 |
COG3177 |
Fic family protein [Transcription]; |
5-55 |
3.97e-06 |
|
Fic family protein [Transcription];
Pssm-ID: 442410 [Multi-domain] Cd Length: 316 Bit Score: 46.99 E-value: 3.97e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 504406949 5 ERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGG 55
Cdd:COG3177 261 ERQRKLLELLFENPVLTASELAELLGVSRRTARRDLKDLVELGILEKVGGG 311
|
|
| COG2345 |
COG2345 |
Predicted transcriptional regulator, ArsR family [Transcription]; |
8-53 |
2.28e-05 |
|
Predicted transcriptional regulator, ArsR family [Transcription];
Pssm-ID: 441914 [Multi-domain] Cd Length: 217 Bit Score: 44.14 E-value: 2.28e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 504406949 8 QQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVS 53
Cdd:COG2345 16 RRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERET 61
|
|
| HTH_ASNC |
smart00344 |
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ... |
5-47 |
1.07e-04 |
|
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)
Pssm-ID: 214628 [Multi-domain] Cd Length: 108 Bit Score: 40.58 E-value: 1.07e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 504406949 5 ERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQG 47
Cdd:smart00344 3 EIDRKILEELQKDARISLAELAKKVGLSPSTVHNRVKRLEEEG 45
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
21-54 |
2.34e-04 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 38.58 E-value: 2.34e-04
10 20 30
....*....|....*....|....*....|....
gi 504406949 21 SINELTERFGVSHMTIRRDVQKLEEQGAVLSVSG 54
Cdd:cd07377 27 SERELAEELGVSRTTVREALRELEAEGLVERRPG 60
|
|
| HTH_GNTR |
smart00345 |
helix_turn_helix gluconate operon transcriptional repressor; |
21-55 |
4.07e-04 |
|
helix_turn_helix gluconate operon transcriptional repressor;
Pssm-ID: 197669 [Multi-domain] Cd Length: 60 Bit Score: 37.55 E-value: 4.07e-04
10 20 30
....*....|....*....|....*....|....*
gi 504406949 21 SINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGG 55
Cdd:smart00345 22 SERELAAQLGVSRTTVREALSRLEAEGLVQRRPGS 56
|
|
| GntR |
pfam00392 |
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ... |
21-55 |
5.34e-04 |
|
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.
Pssm-ID: 306822 [Multi-domain] Cd Length: 64 Bit Score: 37.21 E-value: 5.34e-04
10 20 30
....*....|....*....|....*....|....*
gi 504406949 21 SINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGG 55
Cdd:pfam00392 26 SERELAAEFGVSRTTVREALRRLEAEGLVERRQGR 60
|
|
| HTH_24 |
pfam13412 |
Winged helix-turn-helix DNA-binding; |
5-47 |
6.59e-04 |
|
Winged helix-turn-helix DNA-binding;
Pssm-ID: 404317 [Multi-domain] Cd Length: 45 Bit Score: 36.64 E-value: 6.59e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 504406949 5 ERHQQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQG 47
Cdd:pfam13412 1 ETDRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEG 43
|
|
| UreG |
cd05540 |
urease accessory protein UreG; UreG is one of the four accessory proteins of urease. Urease is ... |
100-143 |
8.89e-04 |
|
urease accessory protein UreG; UreG is one of the four accessory proteins of urease. Urease is an enzyme which catalyzes the decomposition of urea to form ammonia and carbon dioxide. Bacterial urease is a trimer of three subunits which are encoded by genes ureA, ureB, and ureC. Up to four accessory proteins (ureD, ureE, ureF, and ureG) are required for urease catalytical function. UreG may play an important role in nickel incorporation of the urease metallocenter. UreG is a member of the Fer4_NifH superfamily which contains an ATP-binding domain. Proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.
Pssm-ID: 349776 Cd Length: 191 Bit Score: 39.17 E-value: 8.89e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 504406949 100 AGTTTL--ALAREIADREDLLVVTND--------FMVTNLLMEASRCRVIHTGG 143
Cdd:cd05540 11 SGKTALveALCRALRDKYSIAVVTNDiytkedaeFLIRNGALPEERIRGVETGG 64
|
|
| MngR |
COG2188 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
21-93 |
1.07e-03 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441791 [Multi-domain] Cd Length: 238 Bit Score: 39.46 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 21 SINELTERFGVSHMTIRRDVQKLEEQGAVLSVSG-GVR-SANRLASEPSHLTKtalFNEEKKAIGK------LAAQLIPP 92
Cdd:COG2188 31 SERELAEEFGVSRMTVRKALDELVEEGLLERRQGrGTFvAEPKIEYPLSRLTS---FTEELRARGRepstrvLSAERVPA 107
|
.
gi 504406949 93 D 93
Cdd:COG2188 108 D 108
|
|
| COG4189 |
COG4189 |
Predicted transcriptional regulator, ArsR family [Transcription]; |
9-47 |
1.55e-03 |
|
Predicted transcriptional regulator, ArsR family [Transcription];
Pssm-ID: 443343 [Multi-domain] Cd Length: 97 Bit Score: 36.86 E-value: 1.55e-03
10 20 30
....*....|....*....|....*....|....*....
gi 504406949 9 QILALVAERGvMSINELTERFGVSHMTIRRDVQKLEEQG 47
Cdd:COG4189 23 RILRLLAEEP-LNVNELAEALGLPKSTVSYHIRKLEEAG 60
|
|
| MarR_2 |
pfam12802 |
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ... |
9-49 |
3.11e-03 |
|
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.
Pssm-ID: 432797 [Multi-domain] Cd Length: 60 Bit Score: 35.26 E-value: 3.11e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 504406949 9 QILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAV 49
Cdd:pfam12802 9 RVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLV 49
|
|
| cas_HTH |
TIGR01884 |
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ... |
9-54 |
6.27e-03 |
|
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]
Pssm-ID: 273852 [Multi-domain] Cd Length: 203 Bit Score: 36.95 E-value: 6.27e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 504406949 9 QILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSG 54
Cdd:TIGR01884 147 KILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVEQKGR 192
|
|
| HTH_ARSR |
cd00090 |
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ... |
9-57 |
7.76e-03 |
|
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.
Pssm-ID: 238042 [Multi-domain] Cd Length: 78 Bit Score: 34.58 E-value: 7.76e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 504406949 9 QILALVAERGvMSINELTERFGVSHMTIRRDVQKLEEQGAVLSVSGGVR 57
Cdd:cd00090 11 RILRLLLEGP-LTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRR 58
|
|
| BirA |
COG1654 |
Biotin operon repressor [Transcription]; |
8-120 |
8.33e-03 |
|
Biotin operon repressor [Transcription];
Pssm-ID: 441260 [Multi-domain] Cd Length: 324 Bit Score: 36.89 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504406949 8 QQILALVAERGVMSINELTERFGVSHMTIRRDVQKLEEQG-AVLSVSG-GVrsanRLASEPSHLTKTALFNEekkaigkL 85
Cdd:COG1654 7 LKLLRLLADGEFHSGEELAEELGVSRAAVWKHIKALRELGyEIESVPGkGY----RLAEPPDLLDPEEIRAG-------L 75
|
90 100 110
....*....|....*....|....*....|....*
gi 504406949 86 AAQLIPPDSCIYLDAGTTTLALAREIADREDLLVV 120
Cdd:COG1654 76 STKRLGREILYVISSTSTNLLALELAAQGGDAGTV 110
|
|
| |
