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Conserved domains on  [gi|503923930|ref|WP_014157924|]
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MULTISPECIES: GPR1/FUN34/YaaH family transporter [Streptomyces]

Protein Classification

acetate uptake transporter family protein( domain architecture ID 3563)

acetate uptake transporter family protein similar to Aspergillus acetate transporter protein patA and protein alcS

Gene Ontology:  GO:0055085
TCDB:  2.A.96

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Gpr1_Fun34_YaaH super family cl00685
GPR1/FUN34/yaaH family; The Ady2 protein in is required for acetate in Saccharomyces ...
22-205 3.07e-17

GPR1/FUN34/yaaH family; The Ady2 protein in is required for acetate in Saccharomyces cerevisiae, and is probably an acetate transporter. A homolog in Yarrowia lipolytica (GPR1) has a role in acetic acid sensitivity.


The actual alignment was detected with superfamily member COG1584:

Pssm-ID: 469877  Cd Length: 187  Bit Score: 76.39  E-value: 3.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923930  22 IVLRPIASPLPLGFFALGMGSTVLSSLQLGWVPAEqSSILLLLVLIFVVPLQLVSGIFAFLARDAGAGTALLLLGAAWAG 101
Cdd:COG1584    1 AVKDKTANPAPLGLFGFAMTTFLLSLHNAGWFPGS-ALPVLAMALFYGGLAQLIAGIMEFKKGNTFGATAFTSYGAFWLS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923930 102 TSVTSLDSPPGK----PVMAQAVFLLALVPFVLALAGAAAQSKPLFAVLLTLTSVRFAFTGLYEAGLGNALQTAAGWTGL 177
Cdd:COG1584   80 LAGLLLLPKFGLaaaaDAAALGWYLLAWGIFTLFMTIATLKTNKALQVVFLLLDILFFLLALGDFTGSAALTTIAGYEGL 159
                        170       180
                 ....*....|....*....|....*...
gi 503923930 178 GIGVFALYGGLALLVEDGKQRTVLPLFR 205
Cdd:COG1584  160 ICGLLAWYLAAALVLNETFGRTVLPLGK 187
 
Name Accession Description Interval E-value
SatP COG1584
Succinate-acetate transporter SatP [Energy production and conversion];
22-205 3.07e-17

Succinate-acetate transporter SatP [Energy production and conversion];


Pssm-ID: 441192  Cd Length: 187  Bit Score: 76.39  E-value: 3.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923930  22 IVLRPIASPLPLGFFALGMGSTVLSSLQLGWVPAEqSSILLLLVLIFVVPLQLVSGIFAFLARDAGAGTALLLLGAAWAG 101
Cdd:COG1584    1 AVKDKTANPAPLGLFGFAMTTFLLSLHNAGWFPGS-ALPVLAMALFYGGLAQLIAGIMEFKKGNTFGATAFTSYGAFWLS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923930 102 TSVTSLDSPPGK----PVMAQAVFLLALVPFVLALAGAAAQSKPLFAVLLTLTSVRFAFTGLYEAGLGNALQTAAGWTGL 177
Cdd:COG1584   80 LAGLLLLPKFGLaaaaDAAALGWYLLAWGIFTLFMTIATLKTNKALQVVFLLLDILFFLLALGDFTGSAALTTIAGYEGL 159
                        170       180
                 ....*....|....*....|....*...
gi 503923930 178 GIGVFALYGGLALLVEDGKQRTVLPLFR 205
Cdd:COG1584  160 ICGLLAWYLAAALVLNETFGRTVLPLGK 187
 
Name Accession Description Interval E-value
SatP COG1584
Succinate-acetate transporter SatP [Energy production and conversion];
22-205 3.07e-17

Succinate-acetate transporter SatP [Energy production and conversion];


Pssm-ID: 441192  Cd Length: 187  Bit Score: 76.39  E-value: 3.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923930  22 IVLRPIASPLPLGFFALGMGSTVLSSLQLGWVPAEqSSILLLLVLIFVVPLQLVSGIFAFLARDAGAGTALLLLGAAWAG 101
Cdd:COG1584    1 AVKDKTANPAPLGLFGFAMTTFLLSLHNAGWFPGS-ALPVLAMALFYGGLAQLIAGIMEFKKGNTFGATAFTSYGAFWLS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923930 102 TSVTSLDSPPGK----PVMAQAVFLLALVPFVLALAGAAAQSKPLFAVLLTLTSVRFAFTGLYEAGLGNALQTAAGWTGL 177
Cdd:COG1584   80 LAGLLLLPKFGLaaaaDAAALGWYLLAWGIFTLFMTIATLKTNKALQVVFLLLDILFFLLALGDFTGSAALTTIAGYEGL 159
                        170       180
                 ....*....|....*....|....*...
gi 503923930 178 GIGVFALYGGLALLVEDGKQRTVLPLFR 205
Cdd:COG1584  160 ICGLLAWYLAAALVLNETFGRTVLPLGK 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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