|
Name |
Accession |
Description |
Interval |
E-value |
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
19-550 |
3.64e-138 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 408.35 E-value: 3.64e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 19 RALALILIAMVALTGGMFLSGHTTPRLGIDLAGGTSITLKAK------SQPGKPEAINETNMNTAVSIIERRVNGLGVSE 92
Cdd:COG0342 7 LWRLLLLLLVVALSLVAPNGPAKPIKLGLDLQGGVHLLLEVDtdaaldEDGDGIREVTEEALDQAIEILRNRVNELGVSE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 93 AEVQTQGASNIIVNIPKGTNSAQAREQVGTTAQLYFRPVLTvaggaptpegsaspsatgsgkpsatpsakasdpetasdp 172
Cdd:COG0342 87 PVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVDD--------------------------------------- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 173 katpsdgattqgravtgalkkdatptpsgasesdapaatetpdaataalqkkfteldctdkaarAAAGDGVKPEDPTVAC 252
Cdd:COG0342 128 ----------------------------------------------------------------SADAQAAVPAGSELLP 143
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 253 SSEGDAKYLLGPAEVSGTDVDDAKAQFDQQRGIWLVSMEFTDKGSKKFQTITKKLStqqspANQFAISLDGEVVSAPQVN 332
Cdd:COG0342 144 CRDGQPYLLLGPVVLTGDDLTDASAGFDQQTGQPVVSFTLDSEGAKKFADATRENV-----GKPLAIVLDGEVISAPVIQ 218
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 333 ETL-SGSAEISGSFTQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALI 411
Cdd:COG0342 219 EPItGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLV 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 412 ALLSLVASGILTYTIMALlgpaIGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILV 491
Cdd:COG0342 299 ANIALALNVVLLLGVLSL----LGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILD 374
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 503923357 492 SDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLMARTKFFGGGH 550
Cdd:COG0342 375 ANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKLG 433
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
35-555 |
4.85e-127 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 380.72 E-value: 4.85e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 35 MFLSGHTTPRLGIDLAGGTSITLKAKSQ---------------------------------------------------- 62
Cdd:PRK05812 33 LPALGAKPMKLGLDLRGGVHFLLEVDMDdalkkrlesladdlrsllrekkiryggveitfrdaedrdkaiallrklsslt 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 63 PGKPEAINETNMNTAVSIIERRVNGLGVSEAEVQTQGASNIIVNIPKGTNSAQAREQVGTTAQLYFRPVltvaggaptpe 142
Cdd:PRK05812 113 EAELKEITEEALEQAIEIIRNRVNELGVAEPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLV----------- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 143 gsaspsatgsgkpsatpsakasdpetasdpkatpsdgattqgravtgalkkdatptpsgasesdapaatetpdaataalq 222
Cdd:PRK05812 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 223 kkfteldctdkaaraaagdgvkpedptvacssegdakyllgPAEVSGTDVDDAKAQFDQQrGIWLVSMEFTDKGSKKFQT 302
Cdd:PRK05812 182 -----------------------------------------PVILTGDDITDASASFDQQ-GQPVVNITLDSEGAKKFAD 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 303 ITKKLSTQQspanqFAISLDGEVVSAPQVNE-TLSGSAEISGSFTQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGE 381
Cdd:PRK05812 220 ITKANIGKR-----MAIVLDGEVISAPVIQSaITGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGAD 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 382 QLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMALLGpaigFALNLPAVCGAIVAIGITADSFIVYF 461
Cdd:PRK05812 295 SIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVLSLLG----ATLTLPGIAGIVLTIGMAVDANVLIF 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 462 ERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLma 541
Cdd:PRK05812 371 ERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNL-- 448
|
570
....*....|....
gi 503923357 542 rtkFFGGGHPWSGL 555
Cdd:PRK05812 449 ---LYGRRKRLKKL 459
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
45-537 |
1.08e-91 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 287.65 E-value: 1.08e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 45 LGIDLAGGTSITLKAKSQPG--------KPEAINETNMNTAVSIIERRVNGLGVSEAEVQTQGASNIIVNIPKGTNSAQA 116
Cdd:TIGR01129 1 LGLDLRGGARVLLEVDMSTAvvlklseaEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 117 REQVGTTAQLYFRPVLtvaggaptpegsaspsatgsgkpsatpsakasdpetasdpkatpsdgattqgravtgalkkDAT 196
Cdd:TIGR01129 81 KDILGGTATLEFRLVD-------------------------------------------------------------DES 99
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 197 PTPSGASESDAPAATETPDaataalqkkfteldctdkaaraaagdgvkpedptvacSSEGDAKYLLGPAEV--SGTDVDD 274
Cdd:TIGR01129 100 TSPDDALAGNVPAGSELLD-------------------------------------SRSGDPKYYLLKKSPvlTGDHITD 142
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 275 AKAQFDQQRGIWLVSMEFTDKGSKKFQTITKKLStqqspANQFAISLDGEVVSAPQVNETLS-GSAEISGSFTQQSAEDL 353
Cdd:TIGR01129 143 ATSSVDQRSGQPVVSFSLDSEGARIFGDFTQANI-----GKRLAIVLDNKVVSAPTIQEAITgGSGQITGNFTAEEANDL 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 354 ANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMAllgpA 433
Cdd:TIGR01129 218 ALVLRSGALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILS----A 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 434 IGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQG 513
Cdd:TIGR01129 294 FGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKG 373
|
490 500
....*....|....*....|....
gi 503923357 514 FAFTLGLTTLLDVVVVFLFTKPVM 537
Cdd:TIGR01129 374 FAVTLAIGIIASLFTALVFTRLLL 397
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
308-558 |
5.09e-12 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 69.04 E-value: 5.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 308 STQQSPANQ-FAISLDGEVVSAPQVNETLSGSAEISGSFTQQ---------SAEDLANVLSYGALPLSFSEDTVTTVTAA 377
Cdd:NF037998 359 KTTTSNFNQyLDEKIKNYILNNDTINGTKTGAGAGSNTNSNQlivatstetIARTIEALINQTTSGFTFKVNGISEFNPV 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 378 LGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMALLGPAIGfalnLPAVCGAIVAIGITADSF 457
Cdd:NF037998 439 VTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIG----PESITAIFIAIGLVLESC 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 458 IVYFERIRDEI-REGRTLRPAVERAWpRARRTILVSDFVSFLAAAV-LFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKP 535
Cdd:NF037998 515 SLLFEAFKKHLyKNKRSIEESFKIAN-KETIGIIVDALVVLLIPNLsLFWIGSNSIKSFATILLVGVIISLVLVIIVARL 593
|
250 260
....*....|....*....|...
gi 503923357 536 VMTLMARTKFFGGGHPWSGLDPK 558
Cdd:NF037998 594 MIWLTIKLQWFKKYPWLLPLDTD 616
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
373-551 |
2.14e-09 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 59.23 E-value: 2.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 373 TVTAALGGEQLEAG----LIAGAIGLALVVIYLVAYYRGL--ALIALLSLVASGILTYTIMALLGPAIGFALNLPAV-CG 445
Cdd:pfam03176 127 TGPAATVADLRDAGdrdlGLIEAVTLVVIFIILLIVYRSVvaALLPLLTVGLSLGAAQGLVAILAHILGIGLSTFALnLL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 446 AIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLD 525
Cdd:pfam03176 207 VVLLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVD 286
|
170 180
....*....|....*....|....*.
gi 503923357 526 VVVVFLFTKPVMTLMARTKFFGGGHP 551
Cdd:pfam03176 287 VLAALTLLPALLALLGRWGLWPPKRD 312
|
|
| motB |
PRK05996 |
MotB family protein; |
131-256 |
4.91e-04 |
|
MotB family protein;
Pssm-ID: 235665 [Multi-domain] Cd Length: 423 Bit Score: 42.76 E-value: 4.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 131 VLTVAGGAPTPEGSASPSATGSGKPSATPsAKASDPETASDPKATPSDgatTQGRAVTGAlkKDATPTPSGASESDAPAA 210
Cdd:PRK05996 190 VEVTTAGDLLPPGQAREQAQGAKSATAAP-ATVPQAAPLPQAQPKKAA---TEEELIADA--KKAATGEPAANAAKAAKP 263
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 503923357 211 TETPDAATAALQKKfteldcTDKAARAAAGDGVKPEDPTVACSSEG 256
Cdd:PRK05996 264 EPMPDDQQKEAEQL------QAAIAQAIGGVAGKLAEGVTVTPVEG 303
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
391-537 |
7.33e-04 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 42.70 E-value: 7.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 391 AIGLALVVIYLvaYYRGL--ALIALLSLVASGILTYTIMALLGpaigFALNLPAVCGAIVAIGITADSFIVYFERIRDEI 468
Cdd:NF033617 339 AVALVILVVFL--FLRNLraTLIPAVTVPLSLIGTFAVMYLFG----FSINLLTLMALVLAIGLVVDDAIVVVENIHRHI 412
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503923357 469 REGrtlRPAVERAWPRARR---TILVSDFVsfLAAAVLFLVTVGKVQG-----FAFTLGLTTLLDVVVVFLFTkPVM 537
Cdd:NF033617 413 EEG---ESPLEAALKGAREigfTVIAMTLT--LVAVYLPILFMGGLTGrlfreFAVTLAGAVIISGIVALTLT-PMM 483
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
391-542 |
1.12e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 41.93 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 391 AIGLALVVIYLV--AYYRGLA--LIALLSLVASGiltytIMALLGPAIGFA-LNLPAVCGAIVAIGITADSFIVYFE-RI 464
Cdd:NF033617 854 LFLLALAAIYLVlaIQYESFVdpLTILSTVPLAG-----CGALLALALGGQsMNIYAQIGLITLIGLVKKNGILMVEfAN 928
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 465 RDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVT-VGKVQGFAFTLGLTTLLDVVVVF-LFTKPVM-TLMA 541
Cdd:NF033617 929 ELQRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTgAGAESRFPLGIVIVGGLGVGTLFtLFVLPVVyLLLA 1008
|
.
gi 503923357 542 R 542
Cdd:NF033617 1009 R 1009
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
19-550 |
3.64e-138 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 408.35 E-value: 3.64e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 19 RALALILIAMVALTGGMFLSGHTTPRLGIDLAGGTSITLKAK------SQPGKPEAINETNMNTAVSIIERRVNGLGVSE 92
Cdd:COG0342 7 LWRLLLLLLVVALSLVAPNGPAKPIKLGLDLQGGVHLLLEVDtdaaldEDGDGIREVTEEALDQAIEILRNRVNELGVSE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 93 AEVQTQGASNIIVNIPKGTNSAQAREQVGTTAQLYFRPVLTvaggaptpegsaspsatgsgkpsatpsakasdpetasdp 172
Cdd:COG0342 87 PVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVDD--------------------------------------- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 173 katpsdgattqgravtgalkkdatptpsgasesdapaatetpdaataalqkkfteldctdkaarAAAGDGVKPEDPTVAC 252
Cdd:COG0342 128 ----------------------------------------------------------------SADAQAAVPAGSELLP 143
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 253 SSEGDAKYLLGPAEVSGTDVDDAKAQFDQQRGIWLVSMEFTDKGSKKFQTITKKLStqqspANQFAISLDGEVVSAPQVN 332
Cdd:COG0342 144 CRDGQPYLLLGPVVLTGDDLTDASAGFDQQTGQPVVSFTLDSEGAKKFADATRENV-----GKPLAIVLDGEVISAPVIQ 218
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 333 ETL-SGSAEISGSFTQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALI 411
Cdd:COG0342 219 EPItGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLV 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 412 ALLSLVASGILTYTIMALlgpaIGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILV 491
Cdd:COG0342 299 ANIALALNVVLLLGVLSL----LGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILD 374
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 503923357 492 SDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLMARTKFFGGGH 550
Cdd:COG0342 375 ANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKLG 433
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
35-555 |
4.85e-127 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 380.72 E-value: 4.85e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 35 MFLSGHTTPRLGIDLAGGTSITLKAKSQ---------------------------------------------------- 62
Cdd:PRK05812 33 LPALGAKPMKLGLDLRGGVHFLLEVDMDdalkkrlesladdlrsllrekkiryggveitfrdaedrdkaiallrklsslt 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 63 PGKPEAINETNMNTAVSIIERRVNGLGVSEAEVQTQGASNIIVNIPKGTNSAQAREQVGTTAQLYFRPVltvaggaptpe 142
Cdd:PRK05812 113 EAELKEITEEALEQAIEIIRNRVNELGVAEPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLV----------- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 143 gsaspsatgsgkpsatpsakasdpetasdpkatpsdgattqgravtgalkkdatptpsgasesdapaatetpdaataalq 222
Cdd:PRK05812 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 223 kkfteldctdkaaraaagdgvkpedptvacssegdakyllgPAEVSGTDVDDAKAQFDQQrGIWLVSMEFTDKGSKKFQT 302
Cdd:PRK05812 182 -----------------------------------------PVILTGDDITDASASFDQQ-GQPVVNITLDSEGAKKFAD 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 303 ITKKLSTQQspanqFAISLDGEVVSAPQVNE-TLSGSAEISGSFTQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGE 381
Cdd:PRK05812 220 ITKANIGKR-----MAIVLDGEVISAPVIQSaITGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGAD 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 382 QLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMALLGpaigFALNLPAVCGAIVAIGITADSFIVYF 461
Cdd:PRK05812 295 SIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVLSLLG----ATLTLPGIAGIVLTIGMAVDANVLIF 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 462 ERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLma 541
Cdd:PRK05812 371 ERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNL-- 448
|
570
....*....|....
gi 503923357 542 rtkFFGGGHPWSGL 555
Cdd:PRK05812 449 ---LYGRRKRLKKL 459
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
45-537 |
1.08e-91 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 287.65 E-value: 1.08e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 45 LGIDLAGGTSITLKAKSQPG--------KPEAINETNMNTAVSIIERRVNGLGVSEAEVQTQGASNIIVNIPKGTNSAQA 116
Cdd:TIGR01129 1 LGLDLRGGARVLLEVDMSTAvvlklseaEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 117 REQVGTTAQLYFRPVLtvaggaptpegsaspsatgsgkpsatpsakasdpetasdpkatpsdgattqgravtgalkkDAT 196
Cdd:TIGR01129 81 KDILGGTATLEFRLVD-------------------------------------------------------------DES 99
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 197 PTPSGASESDAPAATETPDaataalqkkfteldctdkaaraaagdgvkpedptvacSSEGDAKYLLGPAEV--SGTDVDD 274
Cdd:TIGR01129 100 TSPDDALAGNVPAGSELLD-------------------------------------SRSGDPKYYLLKKSPvlTGDHITD 142
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 275 AKAQFDQQRGIWLVSMEFTDKGSKKFQTITKKLStqqspANQFAISLDGEVVSAPQVNETLS-GSAEISGSFTQQSAEDL 353
Cdd:TIGR01129 143 ATSSVDQRSGQPVVSFSLDSEGARIFGDFTQANI-----GKRLAIVLDNKVVSAPTIQEAITgGSGQITGNFTAEEANDL 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 354 ANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMAllgpA 433
Cdd:TIGR01129 218 ALVLRSGALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILS----A 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 434 IGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQG 513
Cdd:TIGR01129 294 FGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKG 373
|
490 500
....*....|....*....|....
gi 503923357 514 FAFTLGLTTLLDVVVVFLFTKPVM 537
Cdd:TIGR01129 374 FAVTLAIGIIASLFTALVFTRLLL 397
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
20-544 |
3.42e-90 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 294.06 E-value: 3.42e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 20 ALALILIAMVALTGGMFLSGHTTPRLGIDLAGGTSITLKAKSqPGKPEAINETNMNTAVSIIERRVNGLGVSEAEVQTQG 99
Cdd:PRK13024 8 IFFLTLLLLIGIYYASPKFVTKNINLGLDLQGGFEVLLEVSP-ADKGKKADREALDSTVEVLRNRIDGLGVSEPNIQREG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 100 ASNIIVNIPKGTNSAQAREQVGTTAQLYFRPVLTVAGGAPTPEGSAspsatgsgkpsatpsakasdpetasdpkatpsdg 179
Cdd:PRK13024 87 NNRIRVELPGVQDPERARELLGSTAKLTFRDVTDPPPPGVGGPVVG---------------------------------- 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 180 attqgravtgalkkdatptpsgasesdapaatetpdaataalqkkfteldctdkaaRAAAGDGVKpedptvacssegdak 259
Cdd:PRK13024 133 --------------------------------------------------------PDEGKDTAV--------------- 141
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 260 ylLGPAEVSGTDVDDAKAQFDQQ-RGIWLVSMEFTDKGSKKFQTITKKLSTQQSPANQFAISLDGEVVSAPQVNETLS-G 337
Cdd:PRK13024 142 --LNPVLLSGDDLTDAGAKFDQDqTNRPSVSLKLKSEGAKKWAKVTEKNSKKGPPNNRIAIVLDPKVISAPTVNQPINgG 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 338 SAEISGSFTQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLV 417
Cdd:PRK13024 220 SVQISGNFTVEEAKDLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALL 299
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 418 ASGILTYTIMAllgpAIGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSF 497
Cdd:PRK13024 300 LYIFLTLGALS----SLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTL 375
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 503923357 498 LAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLMARTK 544
Cdd:PRK13024 376 IAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLTRLLLELLVKRG 422
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
267-534 |
1.75e-52 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 192.63 E-value: 1.75e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 267 VSGTDVDDAKAQFDQQRGIWLVSMEFTDKGSKKFQTITkklstQQSPANQFAISLDGEVVSAPQVNETLSG-SAEISGSF 345
Cdd:PRK14726 259 VSGENLVDAQPVFDPQTNEPVVTFRLDAEGTQRFAQAT-----QQNVGKHFAIVLDGQVISAPVIDEAITGgEGRISGNF 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 346 TQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYT 425
Cdd:PRK14726 334 SEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAILVAALMIGFYGFLGVIAVIALIVNVVLIIA 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 426 IMALLGPAigfaLNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFL 505
Cdd:PRK14726 414 VLSLLGAT----LTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILFF 489
|
250 260
....*....|....*....|....*....
gi 503923357 506 VTVGKVQGFAFTLGLTTLLDVVVVFLFTK 534
Cdd:PRK14726 490 LGSGAVRGFAVTLAVGILTTVFTAFTLTR 518
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
367-530 |
2.40e-47 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 163.97 E-value: 2.40e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 367 SEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGIltYTIMALLGpAIGFALNLPAVCGA 446
Cdd:TIGR00916 30 SAPVVGTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDV--ILILGVLS-LFGATLTLPGIAGL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 447 IVAIGITADSFIVYFERIRDEIR--EGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLL 524
Cdd:TIGR00916 107 LTIIGYSVDDTVVIFDRIREELRkyKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIA 186
|
....*.
gi 503923357 525 DVVVVF 530
Cdd:TIGR00916 187 GTYSSI 192
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
267-543 |
1.82e-32 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 132.82 E-value: 1.82e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 267 VSGTDVDDAKAQFDQQRGIWLVSMEFTDKGSKKFQTITKKLStqqspANQFAISLDGEVVSAPQVNETLSGSA-EISGSF 345
Cdd:PRK13023 165 LTGHDITDAKASISADDGQPVITLTLDDNGRRRLADLTAQGN-----ENSFAIVVDNQVVSAPTVSGPLDTSElQIEGAF 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 346 TQQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYT 425
Cdd:PRK13023 240 DLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYGILGVIALVALVVNIIILTA 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 426 IMALLGPAIGFAlnlpAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFL 505
Cdd:PRK13023 320 VLSLIGASISLA----SIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFL 395
|
250 260 270
....*....|....*....|....*....|....*...
gi 503923357 506 VTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLMART 543
Cdd:PRK13023 396 LGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWVRT 433
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
268-523 |
9.04e-30 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 124.03 E-value: 9.04e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 268 SGTDVDDAKAQFDQQrGIWLVSMEFTDKGSKKFQ-----TITKKLST---QQSPANQFAISLDGEVVSAPQVNETLSGSA 339
Cdd:PRK12933 317 GGEHIVDARASLGEM-GMAEVNISLDRAGGKKMSdfsrdNIGKPMATsysEYSRDEQGKTKQSEEVISVATIQSQLGDRF 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 340 EISGSFTQQSAEDLANVLSYGAL--PLSFSEDTvtTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLV 417
Cdd:PRK12933 396 RITGAGSYQEAQQLALLLRAGSLtaPVTIVEER--TIGPSLGAENIENGFAALALGMGITLLFMALWYRRLGWVANVALI 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 418 ASGILTYTIMALLGPAIgfaLNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSF 497
Cdd:PRK12933 474 ANMVCLFGLLALIPGAV---LTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQAIDTGFDSAFSTIFDANFTTM 550
|
250 260
....*....|....*....|....*.
gi 503923357 498 LAAAVLFLVTVGKVQGFAFTLGLTTL 523
Cdd:PRK12933 551 ITAVVLYSIGNGPIQGFALTLGLGLL 576
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
39-546 |
1.78e-29 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 124.59 E-value: 1.78e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 39 GHTTPRLGIDLAGGTSITLKAKSQPGKPEAINETNMNTAVSIIERrVNGLGVSEAEVQTQGaSNIIVNIPkGTNSAQARE 118
Cdd:PRK12911 574 GEHVLRFGIDFVGGKQIRLAFKDHQGKQLTDKEGILKVSDELYAR-LNKLGVSEVEMRREG-DHIHLSVP-GSAGISSAE 650
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 119 QVGTTaQLYFRPVltvaggaptPEGSASPSATGSGKPS-------ATPSAKASDPET----ASDPKATPSDGATTQGRAV 187
Cdd:PRK12911 651 ILGTS-KMSFHVV---------NEQFSSYSALRYEVQRfldylwfTARSQDKTSPEAinrlASALFNGDEGSAPASVREA 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 188 TGALKKDATPTPSgaSESDAPAATETPDAATAALQKkftelDCTDKAA------RAAAGDGVKPED--PTVACSsEGdak 259
Cdd:PRK12911 721 VTKLKEEGLAFSK--SGLEGGSASLDTTYSMIAIEK-----DSEEKANplmivfRNYALDGASLKNirPEFAVG-EG--- 789
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 260 YLLG-PAEVSGTDVDDAKAQFDQQRGIWlvSMEFTDKGskkfqtITKKLSTQQSPAN--QFAISLDGEVVSAPQVNETLS 336
Cdd:PRK12911 790 YVLNfSVKDTATFSDARELSPTESFHAW--TSAYCQEG------VSGTKNGQFSGGRgwRMAVVLDGYVVSDPVLNVPLK 861
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 337 GSAEISGSFTQQSAEDLANVLSYGAL---PLSFSEDTVTtvtAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIAL 413
Cdd:PRK12911 862 DHASVSGKFSHREVHRLATDLKSGAMsfvPEVLSEEVIS---PELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIAS 938
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 414 LSLVASGILTYTIMALLGPAigfaLNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSD 493
Cdd:PRK12911 939 GAVLLNLLLIWAALQYLDAP----LTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSESVEAGYKKAFSAIFDSN 1014
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 503923357 494 FVSFLAAAVLFLVTVGKVQGFAFTLglttlldVVVVF--LFTKPVMtlmarTKFF 546
Cdd:PRK12911 1015 LTTILASALLLMLDTGPIKGFALTL-------IIGIFssMFTALFM-----TKFF 1057
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
21-536 |
4.63e-26 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 110.73 E-value: 4.63e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 21 LALILIAMVALTGGMFLSGHTTP-RLGIDLAGGTSITLKAKSqpgkpeAINETNMNTAVSIIERRVNGLGVSEAEVQTQG 99
Cdd:PRK08343 17 IVLVLASIVAIFPPGGGPGGFTNlQYGLDLSGGSWIQLKLEG------PVTQETMDLVVEILESRLNALGLKDIKVYPVG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 100 ASNIIVNIPkGTNSAQAREQVGTTAQLYFRpvltvaggaptpegsaspsatgsgkpsatpsakasdpetasdpkatpsdg 179
Cdd:PRK08343 91 DQYIVVEVP-GVDADTAKEIIEKQGVFEAR-------------------------------------------------- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 180 attqgravtgalkkdatptpsgasesdapAATETPDAATAALQKKFTELDctdkaaraaagdgvkpedptvacssegdak 259
Cdd:PRK08343 120 -----------------------------IQTPGNNNETVLTGDDIESVG------------------------------ 140
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 260 yllgpaevsgtdvddaKAQFDQQRGIWLVSMEFTDKGSKKFQTITK-KLSTQQSPANQFAISLDGEVVSAPQVNETL--- 335
Cdd:PRK08343 141 ----------------SPSQDPSGGAWGVPFTLSEDGAEKFAEVAKgKGATDDPSGHPLDMYLDGELIYAAPLSPDLasg 204
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 336 --SGSAEISGSFT------QQSAEDLANVLSYGALPLSFSEDTVTTVTAALGGEQLEAGLIAGAigLALVVIYLVAYYR- 406
Cdd:PRK08343 205 laSGPVVITVGSTgtteeaKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGSLIAGL--LALLAVALVVFLRy 282
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 407 GLALIALLSLVASGiltYTIMALLGPA--IGFALNLPAVCGAIVAIGITADSFIVyferIRDEI-REGRTLRPAVERAwp 483
Cdd:PRK08343 283 REPRIALPMVITSL---SEVIIILGFAalIGWQLDLASIAGIIAVIGTGVDDLII----ITDEVlHEGKVPSRKVFLS-- 353
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 503923357 484 RARRT---ILVSDFVSFLAAAVLFLVTVGKVQGFAFtlglTTLLDVVVVFLFTKPV 536
Cdd:PRK08343 354 RIKRAffiIFAAAATTIAAMSPLAVMGLGDLKGFAI----TTILGVLIGVLITRPA 405
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
308-558 |
5.09e-12 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 69.04 E-value: 5.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 308 STQQSPANQ-FAISLDGEVVSAPQVNETLSGSAEISGSFTQQ---------SAEDLANVLSYGALPLSFSEDTVTTVTAA 377
Cdd:NF037998 359 KTTTSNFNQyLDEKIKNYILNNDTINGTKTGAGAGSNTNSNQlivatstetIARTIEALINQTTSGFTFKVNGISEFNPV 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 378 LGGEQLEAGLIAGAIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMALLGPAIGfalnLPAVCGAIVAIGITADSF 457
Cdd:NF037998 439 VTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIG----PESITAIFIAIGLVLESC 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 458 IVYFERIRDEI-REGRTLRPAVERAWpRARRTILVSDFVSFLAAAV-LFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKP 535
Cdd:NF037998 515 SLLFEAFKKHLyKNKRSIEESFKIAN-KETIGIIVDALVVLLIPNLsLFWIGSNSIKSFATILLVGVIISLVLVIIVARL 593
|
250 260
....*....|....*....|...
gi 503923357 536 VMTLMARTKFFGGGHPWSGLDPK 558
Cdd:NF037998 594 MIWLTIKLQWFKKYPWLLPLDTD 616
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
374-542 |
3.36e-11 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 66.04 E-value: 3.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 374 VTAALGGEQLEAGLIAGAIGLALVVIYLVAYYR--GLALIALLSLVASGILTYTIMALLGpaIGfaLNLPAVCGAIVAIG 451
Cdd:COG1033 595 LFAAINESVIESQIRSLLLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLLG--IP--LNIATAVVASIALG 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 452 ITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFL 531
Cdd:COG1033 671 IGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLVALLAALL 750
|
170
....*....|.
gi 503923357 532 FTKPVMTLMAR 542
Cdd:COG1033 751 LLPALLLLLDP 761
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
329-518 |
6.02e-11 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 63.06 E-value: 6.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 329 PQVNETLS-GSAEI-SGSFTQQSAEDLANVLSYGALPLSFSEDT--VTTVTAALGGEQLEAGLIAGAIGLALVVIYL-VA 403
Cdd:TIGR00966 39 VVIQEFGSsHTIMIrIPTLDTEQSEELREALEEALKNVDPDAEIrsIDAVGPSVGGELARKAVLALLAALVLILIYItVR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 404 YYRGLALIALLSLVASGILTYTIMALLGpaigFALNLPAVCGAIVAIGITADSFIVYFERIRDEIRE--GRTLRPAVERA 481
Cdd:TIGR00966 119 FEWRFALGAIVALVHDVIITVGVYSLFG----IEVNLTTVAALLTIIGYSINDTVVVFDRIRENLRKytRKTFTEVINLS 194
|
170 180 190
....*....|....*....|....*....|....*...
gi 503923357 482 WPRA-RRTILVSdFVSFLAAAVLFLVTVGKVQGFAFTL 518
Cdd:TIGR00966 195 INQTlSRTINTS-LTTLLAVLALYVFGGGVIKDFSLAL 231
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
373-551 |
2.14e-09 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 59.23 E-value: 2.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 373 TVTAALGGEQLEAG----LIAGAIGLALVVIYLVAYYRGL--ALIALLSLVASGILTYTIMALLGPAIGFALNLPAV-CG 445
Cdd:pfam03176 127 TGPAATVADLRDAGdrdlGLIEAVTLVVIFIILLIVYRSVvaALLPLLTVGLSLGAAQGLVAILAHILGIGLSTFALnLL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 446 AIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLD 525
Cdd:pfam03176 207 VVLLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVD 286
|
170 180
....*....|....*....|....*.
gi 503923357 526 VVVVFLFTKPVMTLMARTKFFGGGHP 551
Cdd:pfam03176 287 VLAALTLLPALLALLGRWGLWPPKRD 312
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
373-542 |
3.78e-09 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 56.46 E-value: 3.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 373 TVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYR-GLALIALLSLVASGILTYTIMALLGpaigFALNLPAVCGAIVAIG 451
Cdd:pfam02355 20 TVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFG----IEVDLATVAALLTIIG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 452 ITADSFIVYFERIRDEIRE--GRTLRPAVERAWPRA-RRTILVSdFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVV 528
Cdd:pfam02355 96 YSVNDTVVVFDRVRENLRKktRATLNEIMNLSINQTlTRTINTS-LTTLLVVVALFVFGGGSLKDFSLALLVGVIVGTYS 174
|
170
....*....|....
gi 503923357 529 VFLFTKPVMTLMAR 542
Cdd:pfam02355 175 SIFIASPILLDLGE 188
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
365-518 |
3.10e-08 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 55.44 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 365 SFSEDTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYR-GLALIALLSLVASGILTYTIMALLgpaiGFALNLPAV 443
Cdd:COG0341 114 DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEwRFAVGAVVALLHDVLITLGIFSLF----GLEFDLTFI 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 444 cGAIVAI-G--ITaDSfIVYFERIRDEIRE--GRTLRPAVERA-WPRARRTILVSdFVSFLAAAVLFLVTVGKVQGFAFT 517
Cdd:COG0341 190 -AALLTIiGysLN-DT-VVVFDRIRENLRKyrKMTLAEIINLSiNQTLSRTINTS-LTTLLVVLALLFFGGETLRDFALA 265
|
.
gi 503923357 518 L 518
Cdd:COG0341 266 L 266
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
374-575 |
3.31e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 56.31 E-value: 3.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 374 VTAALGGEQLEAGLIAGAIGLALVVIYLVAYYRGL--ALIALLSLVASGILTYTIMALLGPAI---GFALNLpavcGAIV 448
Cdd:COG2409 159 LAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLvaALLPLLTAGLAVGVALGLLALLAAFTdvsSFAPNL----LTML 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 449 AIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVV 528
Cdd:COG2409 235 GLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLA 314
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 503923357 529 VFLFTKPVMTLMARTkffggghpwsGLDPKRLGAKPPLRRSRRVNAR 575
Cdd:COG2409 315 ALTLLPALLALLGRR----------VFWPRRPRRRRAAAPESGFWRR 351
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
387-544 |
4.92e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 56.02 E-value: 4.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 387 LIAGAIGLALVVIYLVAYYRGL--ALIALLSLVASGILTYTIMALLGPAIGFAL-NLPAVcgaIVAIGItadSFIVYF-E 462
Cdd:COG1033 221 AIFFPLALLLILLLLFLFFRSLrgVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTiLVPPL---LLAIGI---DYGIHLlN 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 463 RIRDEIREGRTLRPAVERAWPRARRTILVS---DFVSFLAaavLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTL 539
Cdd:COG1033 295 RYREERRKGLDKREALREALRKLGPPVLLTsltTAIGFLS---LLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSL 371
|
....*
gi 503923357 540 MARTK 544
Cdd:COG1033 372 LPRPK 376
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
388-540 |
1.49e-06 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 51.51 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 388 IAGAIGLALVVIYLVAYYRglALIALLSLVASGILTYT----IMALLG-PAIGFALN---LPAVCGAIVAIGITADSFIV 459
Cdd:TIGR00833 748 LISIITLAIVFMILALLLR--APVAPIVLIGSVALSYLwalgLSVLAFqHILGAELHwsvLAGVFVLLVALGVDYNMLLV 825
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 460 YfeRIRDEIREGrtLRPAVERAWPRARRTILVSDFV---SFLAAAVLFLVTVGKvqgFAFTLGLTTLLDVVVVFLFTKPV 536
Cdd:TIGR00833 826 S--RIKEESPAG--NRTGIIRALGSTGGVITAAGLVfagTMAALASAQLTAIAQ---FGFTVGVGILLDTFIVRSVTVPA 898
|
....
gi 503923357 537 MTLM 540
Cdd:TIGR00833 899 LTLL 902
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
392-537 |
3.22e-06 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 50.37 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 392 IGLALVVIYLVAYYRGL--ALIALLSLVASGILTYTIMAllgpAIGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIR 469
Cdd:pfam00873 339 EAIVLVILVMFLFLQNWraTLIPAIAIPLSLLGTFAVMK----AFGFSINTLTLGGLVLAIGLVVDDAIVVVENIERVLE 414
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503923357 470 E-GRTLRPAVERAWPRARRTILVSDFVsfLAAAVLFLVTVGKVQG-----FAFTLGLTTLLDVVVVFLFTkPVM 537
Cdd:pfam00873 415 EnGLKPLEAAYKSMGEIGGALVAIALV--LSAVFLPILFLGGLTGrifrqFAITIVLAILLSVLVALTLT-PAL 485
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
384-533 |
3.70e-06 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 49.85 E-value: 3.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 384 EAGLIAGAIGLALVVIYLVAYYR-GLALIALLSLVASGILTYTIMALLGPaigfALNLPAVCGAIVAIGITADsFIVYFE 462
Cdd:COG4258 640 DALWLLLLALLLILLLLLLRLRSlRRALRVLLPPLLAVLLTLAILGLLGI----PLNLFHLIALLLVLGIGID-YALFFT 714
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503923357 463 RIRDEIREGrtlrpaverawPRARRTILVSDFVSFLAAAVLFLVTVGKVQGFaftlGLTTLLDVVVVFLFT 533
Cdd:COG4258 715 EGLLDKGEL-----------ARTLLSILLAALTTLLGFGLLAFSSTPALRSF----GLTVLLGILLALLLA 770
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
374-481 |
5.36e-06 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 49.72 E-value: 5.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 374 VTAALGGEQLE----AGLIAGAIGLALVVIYLV--AYYR--GLALIALLSLVASGiltytIMALLGPAI-GFALNLPAVC 444
Cdd:COG0841 835 VSIEFTGQAEEeqesFSSLGLAFLLALLLVYLVlaAQFEsfIQPLIILLTVPLAL-----IGALLGLLLtGTPLNIYSQI 909
|
90 100 110
....*....|....*....|....*....|....*...
gi 503923357 445 GAIVAIGI-TADSfIVYFERIRDEIREGRTLRPAVERA 481
Cdd:COG0841 910 GLIMLIGIvVKNA-ILLVDFANQLREEGMSLREAILEA 946
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
341-539 |
1.91e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 47.52 E-value: 1.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 341 ISGSFTQQSAEDLANVLSYGALPLSFSEDTVTTVTAALG-------GEQLEAGLIAGAIGLALVVIYLVAYYRGLALIAL 413
Cdd:TIGR00921 144 LKSDADYKQVVPIYNDVERSLERTNPPSGKFLDVTGSPAinydierEFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLP 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 414 LSLVASGIL-TYTIMALLGPAIGFALNLPAVcgaiVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVS 492
Cdd:TIGR00921 224 LVIILFGVAwVLGIMGWLGIPLYATTLLAVP----MLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIA 299
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 503923357 493 DFVSFLAAAVLFLVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTL 539
Cdd:TIGR00921 300 LLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQS 346
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
373-505 |
1.19e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 44.99 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 373 TVTAALGGEQL----EAGLIAGAIGLALVVIYLVAYYRGLALIA--LLSLVASGILTytiMALLGPAIGfALNLPAVCGA 446
Cdd:TIGR03480 254 TGEVALSDEELatvsEGATVAGLLSFVLVLVLLWLALRSPRLVFavLVTLIVGLILT---AAFATLAVG-HLNLISVAFA 329
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 503923357 447 IVAIGITADSFIVYFERIRDEIREGRTLRPAVERAwprARRTIlVSDFVSFLAAAVLFL 505
Cdd:TIGR03480 330 VLFIGLGVDFAIQFSLRYREERFRGGNHREALSVA---ARRMG-AALLLAALATAAGFF 384
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
50-257 |
1.29e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 44.58 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 50 AGGTSITLKAKSQPGKPEAINETNMNTAVSIIERRVNGLGVSEAEVQTQGASNiivNIPKGTNSAQAREQVGTtaqlyfr 129
Cdd:PHA03169 33 AGRRRGTAARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEKE---ERGQGGPSGSGSESVGS------- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 130 PVLTVAGGAPTPEGSASPSATGSGKPSAtPSAKASDPETASDP----KATPSDGATTQGRAVTGALKKDA---------- 195
Cdd:PHA03169 103 PTPSPSGSAEELASGLSPENTSGSSPES-PASHSPPPSPPSHPgphePAPPESHNPSPNQQPSSFLQPSHedspeepepp 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503923357 196 --TPTPSGASESDAPAATETPDAATAALQKKFTELDCTDKAARAAAGDGVKPEDPTVACSSEGD 257
Cdd:PHA03169 182 tsEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGP 245
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
369-537 |
3.49e-04 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 43.55 E-value: 3.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 369 DTVTTVTAALGgEQLEAGLIAgaIGLALVVIYLvaYYRGL--ALIALLSLVASGILTYTIMALLgpaiGFALNLPAVCGA 446
Cdd:COG0841 321 DQSEFIRASIE-EVVKTLLEA--ILLVVLVVFL--FLRSWraTLIPAVAIPVSLIGTFAVMYLL----GFSLNILTLFAL 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 447 IVAIGITADSFIVYFERIRDEIREGRTLRPAVERAwprARR---TILVSDFVsfLAAAVLFLVTVGKVQG-----FAFTL 518
Cdd:COG0841 392 VLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKG---AREvagAVIASTLT--LVAVFLPLAFMGGITGqlfrqFALTV 466
|
170
....*....|....*....
gi 503923357 519 GLTTLLDVVVVFLFTkPVM 537
Cdd:COG0841 467 AIALLISLFVALTLT-PAL 484
|
|
| motB |
PRK05996 |
MotB family protein; |
131-256 |
4.91e-04 |
|
MotB family protein;
Pssm-ID: 235665 [Multi-domain] Cd Length: 423 Bit Score: 42.76 E-value: 4.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 131 VLTVAGGAPTPEGSASPSATGSGKPSATPsAKASDPETASDPKATPSDgatTQGRAVTGAlkKDATPTPSGASESDAPAA 210
Cdd:PRK05996 190 VEVTTAGDLLPPGQAREQAQGAKSATAAP-ATVPQAAPLPQAQPKKAA---TEEELIADA--KKAATGEPAANAAKAAKP 263
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 503923357 211 TETPDAATAALQKKfteldcTDKAARAAAGDGVKPEDPTVACSSEG 256
Cdd:PRK05996 264 EPMPDDQQKEAEQL------QAAIAQAIGGVAGKLAEGVTVTPVEG 303
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
289-528 |
7.29e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 42.53 E-value: 7.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 289 SMEFTDKGSKKFQTITKKLSTQQSPANQFAISLDGEVVSAPQVNETLSGSAEISGSFTQQSAEDLANVLSygalplsFSE 368
Cdd:PRK13024 489 RYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSDNNQVLVRTYGILSDDEEADTEIVAKLKNALKNDKG-------GTI 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 369 DTVTTVTAALGGEQLEAGLIAGAIGLALVVIYLVAYYR-GLALIALLSLVASGILTYTIMALLgpaiGFALNLPAVCGAI 447
Cdd:PRK13024 562 PSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEwTFSLGAILALLHDVLIVIGFFSLF----RLEVDLTFIAAIL 637
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 448 VAIGITADSFIVYFERIRDEIR--EGRTLRPAVERAwprAR----RTILVSdFVSFLAAAVLFLVTVGKVQGFAFTLglt 521
Cdd:PRK13024 638 TIIGYSINDTVVVFDRIRENLRlyKKKDLREIVNKS---INqtlsRTINTS-LTTLLVLLALLIFGGSSLRNFSLAL--- 710
|
....*..
gi 503923357 522 tLLDVVV 528
Cdd:PRK13024 711 -LVGLIV 716
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
391-537 |
7.33e-04 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 42.70 E-value: 7.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 391 AIGLALVVIYLvaYYRGL--ALIALLSLVASGILTYTIMALLGpaigFALNLPAVCGAIVAIGITADSFIVYFERIRDEI 468
Cdd:NF033617 339 AVALVILVVFL--FLRNLraTLIPAVTVPLSLIGTFAVMYLFG----FSINLLTLMALVLAIGLVVDDAIVVVENIHRHI 412
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503923357 469 REGrtlRPAVERAWPRARR---TILVSDFVsfLAAAVLFLVTVGKVQG-----FAFTLGLTTLLDVVVVFLFTkPVM 537
Cdd:NF033617 413 EEG---ESPLEAALKGAREigfTVIAMTLT--LVAVYLPILFMGGLTGrlfreFAVTLAGAVIISGIVALTLT-PMM 483
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
20-120 |
8.34e-04 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 41.58 E-value: 8.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 20 ALALILIAMVAL-TGGMflsghttpRLGIDLAGGTSITLKAkSQPGKPEAINETnmntavsiierrVNGLGVSEAEVQTQ 98
Cdd:COG0341 22 SAVLILASIVSLfTRGL--------NLGIDFTGGTLIEVSF-EQPVDLEEVREA------------LEEAGLGDASVQTF 80
|
90 100
....*....|....*....|....
gi 503923357 99 GASN-IIVNIP-KGTNSAQAREQV 120
Cdd:COG0341 81 GSDNdVLIRTPpLDGESAEEVEKV 104
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
391-542 |
1.12e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 41.93 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 391 AIGLALVVIYLV--AYYRGLA--LIALLSLVASGiltytIMALLGPAIGFA-LNLPAVCGAIVAIGITADSFIVYFE-RI 464
Cdd:NF033617 854 LFLLALAAIYLVlaIQYESFVdpLTILSTVPLAG-----CGALLALALGGQsMNIYAQIGLITLIGLVKKNGILMVEfAN 928
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 465 RDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFLVT-VGKVQGFAFTLGLTTLLDVVVVF-LFTKPVM-TLMA 541
Cdd:NF033617 929 ELQRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTgAGAESRFPLGIVIVGGLGVGTLFtLFVLPVVyLLLA 1008
|
.
gi 503923357 542 R 542
Cdd:NF033617 1009 R 1009
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
126-258 |
2.42e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 40.99 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 126 LYFRPVLTVAGGAPTPEGSASPSATGSGKPSATPSAKASDPETASDPKATPSDGATTQG---RAVTGALKKDATPTPSGA 202
Cdd:PRK07003 356 LAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAaaaAAATRAEAPPAAPAPPAT 435
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503923357 203 SES-----DAPAATETPDAATAALQKKFTELDCTDKAARAAAGDGVKPEDPTVACSSEGDA 258
Cdd:PRK07003 436 ADRgddaaDGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRA 496
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
117-251 |
3.30e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 40.35 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 117 REQVGTTAQlyfrpVLTVAGGAPTPEGSASPSAtGSGKPSATPSAKASDPETASDPKATPSDGATTQGRAVTGALKKDAT 196
Cdd:PRK07764 575 AEELGGDWQ-----VEAVVGPAPGAAGGEGPPA-PASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVA 648
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 503923357 197 PTPSGASESDAPAATETPDAATAALQKKFTELDCTDKAARAAAGDGVKPEDPTVA 251
Cdd:PRK07764 649 APEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAP 703
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
391-543 |
3.47e-03 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 40.48 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 391 AIGLALVVIYLVAYYRGLALIALLSLVASGILTYTIMAllgpAIGFALNLPAVCGAIVAIGITADSFIVYFERIRDEIR- 469
Cdd:TIGR00915 347 AIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLA----AFGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVMAe 422
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503923357 470 EGRTLRPAVERAWPRARRTILVSDFV---SFLAAAvLFLVTVGKV-QGFAFTLGLTTLLDVVVVFLFTKPVMTLMART 543
Cdd:TIGR00915 423 EGLPPKEATRKSMGQIQGALVGIAMVlsaVFVPMA-FFGGSTGAIyRQFSITIVSAMALSVLVALILTPALCATMLKP 499
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
135-242 |
4.31e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.15 E-value: 4.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 135 AGGAPTPEGSASPSAtgSGKPSATPSAKASDPETASDPKATPSDGATTQGRavtgalkkDATPTPSGASESDAPAATETP 214
Cdd:PHA03307 288 SSSPRERSPSPSPSS--PGSGPAPSSPRASSSSSSSRESSSSSTSSSSESS--------RGAAVSPGPSPSRSPSPSRPP 357
|
90 100
....*....|....*....|....*...
gi 503923357 215 DAATAALQKKFTELDCTDKAARAAAGDG 242
Cdd:PHA03307 358 PPADPSSPRKRPRPSRAPSSPAASAGRP 385
|
|
| Reticulon |
pfam02453 |
Reticulon; Reticulon, also know as neuroendocrine-specific protein (NSP), is a protein of ... |
389-536 |
5.50e-03 |
|
Reticulon; Reticulon, also know as neuroendocrine-specific protein (NSP), is a protein of unknown function which associates with the endoplasmic reticulum. This family represents the C-terminal domain of the three reticulon isoforms and their homologs.
Pssm-ID: 460562 [Multi-domain] Cd Length: 157 Bit Score: 37.85 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503923357 389 AGAIGLALVVIYLVAYYRglalIALLSLVASgiLTYTIMALLgpaIGFALnlpaVCGAIVAIGITadsfIVYFERIRDEI 468
Cdd:pfam02453 14 GGVFGGATALWLLFEVLG----YSLLSLVSK--LLLLLLLVL---FLWAE----YAGKLNRPPPP----IPELELSEETV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503923357 469 RE-GRTLRPAVERAWPRARRTILVSDFVSFL-AAAVLFLVT-VGKVqgfaftLGLTTLLDVVVVFLFTKPV 536
Cdd:pfam02453 77 RElADSLRVLINFALSELRRIALGEDLKLFLkVAVVLWILSyVGSL------FSFLTLLYIGVVLAFTVPL 141
|
|
| |
