|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
122-326 |
6.38e-34 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 124.63 E-value: 6.38e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 122 LQKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEAVYINNALEKACQIKNLTTALFSHSVAEN 201
Cdd:COG2205 2 LEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 202 EEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVkDSIAEGFAINVDIQQFRRVFDNLCSNALKYADPRRPISFDVML 281
Cdd:COG2205 82 GKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLEL-DLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503145266 282 EPDTLRIIQTN------------------QVRKNSGGESFGIGLKTCEKIAERHEGTFksWIE 326
Cdd:COG2205 161 EGDGVRISVSDngpgipeeeleriferfyRGDNSRGEGGTGLGLAIVKRIVEAHGGTI--WVE 221
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
100-320 |
1.43e-13 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 71.01 E-value: 1.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 100 IPVEGDDELTALAIQLNDMRRTLQKQINEREtairenhEMVTAISHDIRTPLTSVICYLDLIRDGKVK-SPEEeavyINN 178
Cdd:NF012163 211 VTPTSNDELGKLAQDFNQLASTLEKNEQMRR-------DFMADISHELRTPLAVLRAELEAIQDGIRKfTPES----LDS 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 179 ALEKACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVkdSIAEGFAINVDIQQFRRVF 258
Cdd:NF012163 280 LQAEVGTLTKLVDDLHDLSMSDEGALAYQKASVDLVPLLEVEGGAFRERFASAGLELEV--SLPDSSLVFGDRDRLMQLF 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 259 DNLCSNALKYADP---------RRPISFDVMLE-------PDTL-----RIIQTNQVRKNSGGESfGIGLKTCEKIAERH 317
Cdd:NF012163 358 NNLLENSLRYTDSggslhisasQRPKEVTLTVAdsapgvsDEQLarlfeRFYRVEVSRNRASGGS-GLGLAISLNIVQAH 436
|
...
gi 503145266 318 EGT 320
Cdd:NF012163 437 GGT 439
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
128-338 |
3.52e-11 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 64.29 E-value: 3.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 128 ERETaIRenHEMVTAISHDIRTPLT-----SVICYLDLIRDGKVKSPEEEAV---------YINNALEKAcQIKnlttal 193
Cdd:PRK10490 659 EREQ-LR--NALLAALSHDLRTPLTvlfgqAEILTLDLASEGSPHARQASEIrqqvlnttrLVNNLLDMA-RIQ------ 728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 194 fSHSVAENEEVMFHYELIdGNELlaQVLSESVflleeKGLTVQVkDSIAEGFAINVDIQQFRRVFDNLCSNALKYADPRR 273
Cdd:PRK10490 729 -SGGFNLRKEWLTLEEVV-GSAL--QMLEPGL-----SGHPINL-SLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQA 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 274 PISFDVMLEPDTLRI--------IQTNQ----------VRKNSGGESFGIGLKTCEKIAERHEGTFksWIE---KGEFVA 332
Cdd:PRK10490 799 EIGIDAHVEGERLQLdvwdngpgIPPGQeqlifdkfarGNKESAIPGVGLGLAICRAIVEVHGGTI--WAEnrpEGGACF 876
|
....*.
gi 503145266 333 IWTLPL 338
Cdd:PRK10490 877 RVTLPL 882
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
107-320 |
2.61e-09 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 58.17 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 107 ELTALAIQLNDMRRTLqkqinerETAIRENHEMVTAISHDIRTPLTSVICY----LDLIRDGKvksPEEEAVYINnaLEK 182
Cdd:TIGR01386 219 ELRELAQSFNAMLGRL-------EDAFQRLSQFSADLAHELRTPLTNLLGQtqvaLSQPRTGE---EYREVLESN--LEE 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 183 ACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVKdsiAEGFAInVDIQQFRRVFDNLC 262
Cdd:TIGR01386 287 LERLSRMVSDMLFLARADNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVE---GEGLVR-GDPQMFRRAISNLL 362
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 503145266 263 SNALKYADP---------RRPISFDVMLE-------PDTL-----RIIQTNQVRKNSgGESFGIGLKTCEKIAERHEGT 320
Cdd:TIGR01386 363 SNALRHTPDggtitvrieRRSDEVRVSVSnpgpgipPEHLsrlfdRFYRVDPARSNS-GEGTGLGLAIVRSIMEAHGGR 440
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
250-338 |
1.72e-07 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 49.18 E-value: 1.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 250 DIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRII---------------------QTNQVRKNSGGesFGIGLK 308
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITvedngpgippedlekifepffRTDKRSRKIGG--TGLGLS 79
|
90 100 110
....*....|....*....|....*....|..
gi 503145266 309 TCEKIAERHEGT--FKSWIEKGeFVAIWTLPL 338
Cdd:smart00387 80 IVKKLVELHGGEisVESEPGGG-TTFTITLPL 110
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
138-189 |
4.69e-07 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 46.44 E-value: 4.69e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRDGkvKSPEEEAVYINNALEKACQIKNL 189
Cdd:pfam00512 4 EFLANLSHELRTPLTAIRGYLELLRDE--KLDEEQREYLETILRSAERLLRL 53
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
255-329 |
7.14e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 46.94 E-value: 7.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 255 RRVFDNLCSNALKYADPRRPISFDVMLEPDTLRiiQTNQVRKNSGG----------------------ESFGIGLKTCEK 312
Cdd:cd16921 2 GQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEE--WTFYVRDNGIGidpeyaekvfgifqrlhsreeyEGTGVGLAIVRK 79
|
90
....*....|....*..
gi 503145266 313 IAERHEGtfKSWIEKGE 329
Cdd:cd16921 80 IIERHGG--RIWLESEP 94
|
|
| HAMP |
pfam00672 |
HAMP domain; |
78-124 |
9.38e-06 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 42.23 E-value: 9.38e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 503145266 78 IRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQK 124
Cdd:pfam00672 7 LRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
78-122 |
1.96e-05 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 41.28 E-value: 1.96e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 503145266 78 IRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTL 122
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
78-127 |
3.69e-04 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 38.00 E-value: 3.69e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 503145266 78 IRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQIN 127
Cdd:smart00304 4 LRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
14-139 |
1.55e-03 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 40.00 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 14 LGLTIMKYFGISFVIALASGVATTLLLNCFIRENGISGETVELLSYMVTIAVLFVVFLKLFHKKIRY-----IHTLEHGI 88
Cdd:COG2972 113 LLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRsitrpIKRLKKAM 192
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 503145266 89 EIIEGGGLEYpIPVEGDDELTALAIQLNDMRRTLQKQINERETAIRENHEM 139
Cdd:COG2972 193 KKVEKGDLVR-LEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKKEA 242
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
122-326 |
6.38e-34 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 124.63 E-value: 6.38e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 122 LQKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEAVYINNALEKACQIKNLTTALFSHSVAEN 201
Cdd:COG2205 2 LEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 202 EEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVkDSIAEGFAINVDIQQFRRVFDNLCSNALKYADPRRPISFDVML 281
Cdd:COG2205 82 GKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLEL-DLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503145266 282 EPDTLRIIQTN------------------QVRKNSGGESFGIGLKTCEKIAERHEGTFksWIE 326
Cdd:COG2205 161 EGDGVRISVSDngpgipeeeleriferfyRGDNSRGEGGTGLGLAIVKRIVEAHGGTI--WVE 221
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
9-328 |
2.96e-30 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 118.50 E-value: 2.96e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 9 IFRSKLGLTIMKYFGISFVIALASGVATTLLLNCFIRENGISGETVELLSYMVTIAVLFVVFLKLFHKKIRYIHTLEHGI 88
Cdd:COG5002 37 LLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 89 EIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTL-QKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKVK 167
Cdd:COG5002 117 LLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAvERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAAD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 168 SPEEEAVYINNALEKACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVkDSIAEGFAI 247
Cdd:COG5002 197 DPEERREYLEIILEEAERLSRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELEL-DLPEDPLLV 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 248 NVDIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRII---------------------QTNQVR-KNSGGesFGI 305
Cdd:COG5002 276 LGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISvrdtgigipeedlpriferfyRVDKSRsRETGG--TGL 353
|
330 340
....*....|....*....|....*
gi 503145266 306 GLKTCEKIAERHEGT--FKSWIEKG 328
Cdd:COG5002 354 GLAIVKHIVEAHGGRiwVESEPGKG 378
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
27-320 |
1.04e-27 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 110.38 E-value: 1.04e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 27 VIALASGVATTLLLNCFIRENGISGETVELLSYMVTIAVLFVVFLKLFHKKIRYIHTLEHGIEIIEGGGLEYPIPVEGDD 106
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 107 ELTALAIQLNDMRRTLQKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKvksPEEEAVYINNALEKACQI 186
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL---DEEQREYLETILRSADRL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 187 KNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVkDSIAEGFAINVDIQQFRRVFDNLCSNAL 266
Cdd:COG0642 158 LRLINDLLDLSRLEAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELEL-DLPDDLPTVRGDPDRLRQVLLNLLSNAI 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503145266 267 KYADPRRPISFDVMLEPDTLRIIQTN------------------QVRKNSGGESFGIGLKTCEKIAERHEGT 320
Cdd:COG0642 237 KYTPEGGTVTVSVRREGDRVRISVEDtgpgippedlerifepffRTDPSRRGGGTGLGLAIVKRIVELHGGT 308
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
52-326 |
1.72e-23 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 101.02 E-value: 1.72e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 52 ETVELLSYMVTIAVLFVVFLKLFHKKIRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINERET 131
Cdd:COG4251 198 LLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELER 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 132 AIRENHEMVTAISHDIRTPLTSVICYLDLI-RDGKVKSPEEEAVYINNALEKACQIKNLTTALFSHSVAENEEVmfHYEL 210
Cdd:COG4251 278 SNEELEQFAYVASHDLREPLRKISGFSQLLeEDYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSRVGRQEL--EFEP 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 211 IDGNELLAQVLSESVFLLEEKGLTVQvkdsIAEGFAINVDIQQFRRVFDNLCSNALKYADPRRP--ISFDVMLEPDTLRI 288
Cdd:COG4251 356 VDLNELLEEVLEDLEPRIEERGAEIE----VGPLPTVRGDPTLLRQVFQNLISNAIKYSRPGEPprIEIGAEREGGEWVF 431
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 503145266 289 I--------------------QTNQVRKNSGGEsfGIGLKTCEKIAERHEGTFksWIE 326
Cdd:COG4251 432 SvrdngigidpeyaekifeifQRLHSRDEYEGT--GIGLAIVKKIVERHGGRI--WVE 485
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
100-320 |
1.43e-13 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 71.01 E-value: 1.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 100 IPVEGDDELTALAIQLNDMRRTLQKQINEREtairenhEMVTAISHDIRTPLTSVICYLDLIRDGKVK-SPEEeavyINN 178
Cdd:NF012163 211 VTPTSNDELGKLAQDFNQLASTLEKNEQMRR-------DFMADISHELRTPLAVLRAELEAIQDGIRKfTPES----LDS 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 179 ALEKACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVkdSIAEGFAINVDIQQFRRVF 258
Cdd:NF012163 280 LQAEVGTLTKLVDDLHDLSMSDEGALAYQKASVDLVPLLEVEGGAFRERFASAGLELEV--SLPDSSLVFGDRDRLMQLF 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 259 DNLCSNALKYADP---------RRPISFDVMLE-------PDTL-----RIIQTNQVRKNSGGESfGIGLKTCEKIAERH 317
Cdd:NF012163 358 NNLLENSLRYTDSggslhisasQRPKEVTLTVAdsapgvsDEQLarlfeRFYRVEVSRNRASGGS-GLGLAISLNIVQAH 436
|
...
gi 503145266 318 EGT 320
Cdd:NF012163 437 GGT 439
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
128-338 |
3.52e-11 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 64.29 E-value: 3.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 128 ERETaIRenHEMVTAISHDIRTPLT-----SVICYLDLIRDGKVKSPEEEAV---------YINNALEKAcQIKnlttal 193
Cdd:PRK10490 659 EREQ-LR--NALLAALSHDLRTPLTvlfgqAEILTLDLASEGSPHARQASEIrqqvlnttrLVNNLLDMA-RIQ------ 728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 194 fSHSVAENEEVMFHYELIdGNELlaQVLSESVflleeKGLTVQVkDSIAEGFAINVDIQQFRRVFDNLCSNALKYADPRR 273
Cdd:PRK10490 729 -SGGFNLRKEWLTLEEVV-GSAL--QMLEPGL-----SGHPINL-SLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQA 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 274 PISFDVMLEPDTLRI--------IQTNQ----------VRKNSGGESFGIGLKTCEKIAERHEGTFksWIE---KGEFVA 332
Cdd:PRK10490 799 EIGIDAHVEGERLQLdvwdngpgIPPGQeqlifdkfarGNKESAIPGVGLGLAICRAIVEVHGGTI--WAEnrpEGGACF 876
|
....*.
gi 503145266 333 IWTLPL 338
Cdd:PRK10490 877 RVTLPL 882
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
79-320 |
7.57e-11 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 62.51 E-value: 7.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 79 RYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINERETAIRENH----------------EMVTA 142
Cdd:COG4191 69 LALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRelqeqlvqseklaalgELAAG 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 143 ISHDIRTPLTSVICYLDLIRDGKVKSPEEEAV--YINNALEKACQIKNLTTALFSHSVAENEEVmfhyELIDGNELLAQV 220
Cdd:COG4191 149 IAHEINNPLAAILGNAELLRRRLEDEPDPEELreALERILEGAERAAEIVRSLRAFSRRDEEER----EPVDLNELIDEA 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 221 LSESVFLLEEKGLTVqVKDSIAEGFAINVDIQQFRRVFDNLCSNALkYA---DPRRPISFDVMLEPDTLRIiqtnQVRKN 297
Cdd:COG4191 225 LELLRPRLKARGIEV-ELDLPPDLPPVLGDPGQLEQVLLNLLINAI-DAmeeGEGGRITISTRREGDYVVI----SVRDN 298
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 503145266 298 SGG----------ESF----------GIGLKTCEKIAERHEGT 320
Cdd:COG4191 299 GPGippevlerifEPFfttkpvgkgtGLGLSISYGIVEKHGGR 341
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
61-270 |
4.81e-10 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 60.81 E-value: 4.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 61 VTIAVLFVVFLKLFHKKIRYI-HTLEHGIEIIEGGG---LEYPIPVEGDDELTALAIQLNDMRRTLQKQ-------INER 129
Cdd:PRK15347 301 FALLILVLLTSVLFLLLRRYLaKPLWRFVDIINKTGpaaLEPRLPENRLDELGSIAKAYNQLLDTLNEQydtlenkVAER 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 130 -----------ETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKVkSPE-----EEAVY--------INNALEkacq 185
Cdd:PRK15347 381 tqalaeakqraEQANKRKSEHLTTISHEIRTPLNGVLGALELLQNTPL-TAEqmdlaDTARQctlsllaiINNLLD---- 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 186 iknlttalFSHsvAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQ--VKDSIAEGFAInvDIQQFRRVFDNLCS 263
Cdd:PRK15347 456 --------FSR--IESGQMTLSLEETALLPLLDQAMLTIQGPAQSKSLTLRtfVGAHVPLYLHL--DSLRLRQILVNLLG 523
|
....*..
gi 503145266 264 NALKYAD 270
Cdd:PRK15347 524 NAVKFTE 530
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
113-322 |
2.13e-09 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 58.43 E-value: 2.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 113 IQLNDMRRTLQKQineRETAIREnheMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEAVYINNALE---KACQ-IKN 188
Cdd:COG5000 184 IVFDDITELLRAE---RLAAWGE---LARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDREDLERALDtiiRQVDrLKR 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 189 LTTAL--FSHSVAENeevmfhYELIDGNELLAQVLSESVFLLEEKGLTVQVkDSIAEGFAINVDIQQFRRVFDNLCSNAL 266
Cdd:COG5000 258 IVDEFldFARLPEPQ------LEPVDLNELLREVLALYEPALKEKDIRLEL-DLDPDLPEVLADRDQLEQVLINLLKNAI 330
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503145266 267 KYADPRRPISFDVMLEPDTLRI-IQ------TNQVR----------KNSGgesFGIGLKTCEKIAERHEGTFK 322
Cdd:COG5000 331 EAIEEGGEIEVSTRREDGRVRIeVSdngpgiPEEVLerifepffttKPKG---TGLGLAIVKKIVEEHGGTIE 400
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
107-320 |
2.61e-09 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 58.17 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 107 ELTALAIQLNDMRRTLqkqinerETAIRENHEMVTAISHDIRTPLTSVICY----LDLIRDGKvksPEEEAVYINnaLEK 182
Cdd:TIGR01386 219 ELRELAQSFNAMLGRL-------EDAFQRLSQFSADLAHELRTPLTNLLGQtqvaLSQPRTGE---EYREVLESN--LEE 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 183 ACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVKdsiAEGFAInVDIQQFRRVFDNLC 262
Cdd:TIGR01386 287 LERLSRMVSDMLFLARADNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVE---GEGLVR-GDPQMFRRAISNLL 362
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 503145266 263 SNALKYADP---------RRPISFDVMLE-------PDTL-----RIIQTNQVRKNSgGESFGIGLKTCEKIAERHEGT 320
Cdd:TIGR01386 363 SNALRHTPDggtitvrieRRSDEVRVSVSnpgpgipPEHLsrlfdRFYRVDPARSNS-GEGTGLGLAIVRSIMEAHGGR 440
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
56-331 |
5.29e-09 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 57.39 E-value: 5.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 56 LLSYMVTIAVLFVVFLKLFHKKIRYI---HTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINERETA 132
Cdd:COG4192 327 LLLAIALLSLLLAVLINYFYVRRRLVkrlNALSDAMAAIAAGDLDVPIPVDGNDEIGRIARLLRVFRDQAIEKTQELETE 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 133 I-----RENH------------------EMVTAISHDIRTPLTSVICYL-DLIRDGKVKSPEEEAVYINNALEKACQIKN 188
Cdd:COG4192 407 IeerkrIEKNlrqtqdeliqaakmavvgQTMTSLAHELNQPLNAMSMYLfSAKKALEQENYAQLPTSLDKIEGLIERMDK 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 189 LTTALFSHSVAENEEVMFhyelidgnELLAQVLSESVFLLEEKGLTVQVKDSIAEGFAINVDIQQFRRVFDNLCSNALKY 268
Cdd:COG4192 487 IIKSLRQFSRKSDTPLQP--------VDLRQVIEQAWELVESRAKPQQITLHIPDDLMVQGDQVLLEQVLVNLLVNALDA 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 269 ADPRRPISFDVMLEPDTLRIiqtnQVRKNSGGES----------------FGIGLKTCEKIAERHEG--TFKSWIEKGEF 330
Cdd:COG4192 559 VATQPQISVDLLSNAENLRV----AISDNGNGWPlvdklftpftttkevgLGLGLSICRSIMQQFGGdlYLASTLERGAM 634
|
.
gi 503145266 331 V 331
Cdd:COG4192 635 V 635
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
102-339 |
7.23e-09 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 56.50 E-value: 7.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 102 VEGDDELTALAIQLND----MRR---TLQKQINERETAIRenheMVtaiSHDIRTPLTSVICYLDLIRDGKVKSPEEEAV 174
Cdd:PRK09303 117 EIDSGRYSQELLQLSDelfvLRQeneTLLEQLKFKDRVLA----ML---AHDLRTPLTAASLALETLELGQIDEDTELKP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 175 YINNALEKacQIKN-------LTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQ--VKDSIAEGF 245
Cdd:PRK09303 190 ALIEQLQD--QARRqleeierLITDLLEVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLEIQtdIPSDLPSVY 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 246 AinvDIQQFRRVFDNLCSNALKYADPRRPISFdVMLEPDTLRI------------------IQTNQVR--KNSGGESFGI 305
Cdd:PRK09303 268 A---DQERIRQVLLNLLDNAIKYTPEGGTITL-SMLHRTTQKVqvsicdtgpgipeeeqerIFEDRVRlpRDEGTEGYGI 343
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 503145266 306 GLKTCEKIAERHEGtfKSWIE----KG---EFvaiwTLPLY 339
Cdd:PRK09303 344 GLSVCRRIVRVHYG--QIWVDsepgQGscfHF----TLPVY 378
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
102-320 |
4.91e-08 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 54.25 E-value: 4.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 102 VEGDDELTALAIQLNDMRRTLQKqineretaireNHEMVTA----ISHDIRTPLTSVICYLDLIRDGkVKSPEEEAVyin 177
Cdd:PRK10549 213 PTSRDELGRLAQDFNQLASTLEK-----------NEQMRRDfmadISHELRTPLAVLRGELEAIQDG-VRKFTPESV--- 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 178 NALEkaCQIKNLTTA---LFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVK-DSIAEGFAinvDIQQ 253
Cdd:PRK10549 278 ASLQ--AEVGTLTKLvddLHQLSLSDEGALAYRKTPVDLVPLLEVAGGAFRERFASRGLTLQLSlPDSATVFG---DPDR 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 254 FRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRII-----------QTNQV----------RKNSGGESfGIGLKTCEK 312
Cdd:PRK10549 353 LMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTfadsapgvsdeQLQKLferfyrtegsRNRASGGS-GLGLAICLN 431
|
....*...
gi 503145266 313 IAERHEGT 320
Cdd:PRK10549 432 IVEAHNGR 439
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
114-319 |
1.40e-07 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 53.20 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 114 QLNDMRRTLQKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIrDGKVKSPEEEAVYINNALEKACQIKNLTTAL 193
Cdd:PRK09959 690 ETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELL-SGSGLSKEQRVEAISLAYATGQSLLGLIGEI 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 194 FSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVKDSIAEGFAINVDIQQFRRVFDNLCSNALKYA---- 269
Cdd:PRK09959 769 LDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFTtega 848
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503145266 270 -----------DPRRPISFDVMLEPDTL----------RIIQTNQVRKNSGGesfGIGLKTCEKIAERHEG 319
Cdd:PRK09959 849 vkittslghidDNHAVIKMTIMDSGSGLsqeeqqqlfkRYSQTSAGRQQTGS---GLGLMICKELIKNMQG 916
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
250-338 |
1.72e-07 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 49.18 E-value: 1.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 250 DIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRII---------------------QTNQVRKNSGGesFGIGLK 308
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITvedngpgippedlekifepffRTDKRSRKIGG--TGLGLS 79
|
90 100 110
....*....|....*....|....*....|..
gi 503145266 309 TCEKIAERHEGT--FKSWIEKGeFVAIWTLPL 338
Cdd:smart00387 80 IVKKLVELHGGEisVESEPGGG-TTFTITLPL 110
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
85-266 |
2.99e-07 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 51.39 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 85 EHGIEIIEGGGLEYPI-----PVEGDDELTALAIQLNDmrRTLQKQInERETAIRENHEMVTA----ISHDIRTPLTSVI 155
Cdd:COG3852 78 EREVTLRRKDGEERPVdvsvsPLRDAEGEGGVLLVLRD--ITERKRL-ERELRRAEKLAAVGElaagLAHEIRNPLTGIR 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 156 CYLDLIRDGkvKSPEEEAVYINNALEKACQIKNLTTAL--FSHSVAeneevmFHYELIDGNELLAQVLSesvFLLEEKGL 233
Cdd:COG3852 155 GAAQLLERE--LPDDELREYTQLIIEEADRLNNLVDRLlsFSRPRP------PEREPVNLHEVLERVLE---LLRAEAPK 223
|
170 180 190
....*....|....*....|....*....|....*..
gi 503145266 234 TVQVK----DSIAEgfaINVDIQQFRRVFDNLCSNAL 266
Cdd:COG3852 224 NIRIVrdydPSLPE---VLGDPDQLIQVLLNLVRNAA 257
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
138-339 |
4.43e-07 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 51.13 E-value: 4.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRDGKVkspEEEAVYINNALEKACQIKNLTTALFshSVAENEEVmfHYELIDGNELL 217
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKGFIQLLKDTID---EEQKTYLDIMLSELDRIESIISEFL--VLAKPQAI--KYEPKDLNTLI 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 218 AQVLSesvfLLEEKGL--TVQVKDSIAEGFA-INVDIQQFRRVFDNLCSNALKyadprrpisfdVMLEPDTLRIIQT--- 291
Cdd:COG5809 345 EEVIP----LLQPQALlkNVQIELELEDDIPdILGDENQLKQVFINLLKNAIE-----------AMPEGGNITIETKaed 409
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503145266 292 -NQVR---KNSG-----------GESF--------GIGLKTCEKIAERHEG--TFKSWIEKGEFVAIwTLPLY 339
Cdd:COG5809 410 dDKVVisvTDEGcgipeerlkklGEPFyttkekgtGLGLMVSYKIIEEHGGkiTVESEVGKGTTFSI-TLPIK 481
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
138-189 |
4.69e-07 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 46.44 E-value: 4.69e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRDGkvKSPEEEAVYINNALEKACQIKNL 189
Cdd:pfam00512 4 EFLANLSHELRTPLTAIRGYLELLRDE--KLDEEQREYLETILRSAERLLRL 53
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
255-329 |
7.14e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 46.94 E-value: 7.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 255 RRVFDNLCSNALKYADPRRPISFDVMLEPDTLRiiQTNQVRKNSGG----------------------ESFGIGLKTCEK 312
Cdd:cd16921 2 GQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEE--WTFYVRDNGIGidpeyaekvfgifqrlhsreeyEGTGVGLAIVRK 79
|
90
....*....|....*..
gi 503145266 313 IAERHEGtfKSWIEKGE 329
Cdd:cd16921 80 IIERHGG--RIWLESEP 94
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
138-189 |
7.16e-07 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 46.02 E-value: 7.16e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRDGKVksPEEEAVYINNALEKACQIKNL 189
Cdd:smart00388 4 EFLANLSHELRTPLTAIRGYLELLLDTEL--SEEQREYLETILREAERLLRL 53
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
138-338 |
8.23e-07 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 50.50 E-value: 8.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRDGKvkspEEEAVYINNALEKACQIKNLTTALFShsVAENEEVMFHYELIdgNELL 217
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKGFLQLLQPGI----EDKEEYFDIMLSELDRIESIISEFLA--LAKPQAVNKEKENI--NELI 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 218 AQV--LSESVFLLEEKGLTVQVKDSIAEgfaINVDIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRIIQTNQ-- 293
Cdd:COG5805 361 QDVvtLLETEAILHNIQIRLELLDEDPF---IYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEgi 437
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 503145266 294 ----VRKNSGGESF--------GIGLKTCEKIAERHEGT--FKSWIEKGEFVAIwTLPL 338
Cdd:COG5805 438 gipeERLKKLGEPFfttkekgtGLGLMVSYKIIENHNGTidIDSKVGKGTTFTI-TLPL 495
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
56-322 |
1.47e-06 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 49.52 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 56 LLSYMVTIAVLFVVFLKLFHKKI-RYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINERetAIr 134
Cdd:PRK09467 155 LFRYTLAIGLLSVAGGWLFIRIQnRPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQMAAGIKQLEDDR--TL- 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 135 enheMVTAISHDIRTPLTSvicyldlIR-DGKVKSPEEE--AVYINNALEKACQIKNLTTALFSHsvaENEEVMfhyELI 211
Cdd:PRK09467 232 ----LMAGVSHDLRTPLTR-------IRlATEMMSEEDGylAESINKDIEECNAIIEQFIDYLRT---GQEMPM---EMA 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 212 DGNELLAQVLSesvfllEEKGLTVQVKDSIAEGfAINVDIQ--QFRRVFDNLCSNALKYADPRRPIS---------FDV- 279
Cdd:PRK09467 295 DLNALLGEVIA------AESGYEREIETALQPG-PIEVPMNpiAIKRALANLVVNAARYGNGWIKVSsgtegkrawFQVe 367
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 503145266 280 -------------MLEPDTlriiQTNQVRKNSGGesfGIGLKTCEKIAERHEGTFK 322
Cdd:PRK09467 368 ddgpgippeqlkhLFQPFT----RGDSARGSSGT---GLGLAIVKRIVDQHNGKVE 416
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
118-266 |
1.53e-06 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 49.58 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 118 MRRTLQKQinERETAIrenHEMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEavYINNALEKACQIKNLTTAL--FS 195
Cdd:PRK11360 377 LQRRVARQ--ERLAAL---GELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQE--YLSVVLREVDRLNKVIDQLleFS 449
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503145266 196 HSvaeNEEVMFHYELidgNELLAQVLsesvFLLEEKGLTVQVKDSIA---EGFAINVDIQQFRRVFDNLCSNAL 266
Cdd:PRK11360 450 RP---RESQWQPVSL---NALVEEVL----QLFQTAGVQARVDFETEldnELPPIWADPELLKQVLLNILINAV 513
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
138-193 |
2.43e-06 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 44.51 E-value: 2.43e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRDGkVKSPEEEAVYINNALEKACQIKNLTTAL 193
Cdd:cd00082 6 EFLANVSHELRTPLTAIRGALELLEEE-LLDDEEQREYLERIREEAERLLRLINDL 60
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
56-320 |
2.48e-06 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 49.00 E-value: 2.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 56 LLSYMVTIAVLFVVFLKlfHKKIRyihTLEHGIEIIEGGGLEYPI-PVEGDDELTALAIQLNDMrrtlqkqINERETAIR 134
Cdd:PRK09835 193 VISLLIVFIVLLAVHKG--HAPIR---SVSRQIQNITSKDLDVRLdPQTVPIELEQLVLSFNHM-------IERIEDVFT 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 135 ENHEMVTAISHDIRTPLTSVICYLDL-IRDGKVKSPEEEAVYINnaLEKACQIKNLTTALFSHSVAENEEVMFHYELIDg 213
Cdd:PRK09835 261 RQSNFSADIAHEIRTPITNLITQTEIaLSQSRSQKELEDVLYSN--LEELTRMAKMVSDMLFLAQADNNQLIPEKKMLD- 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 214 neLLAQVLSesVF-----LLEEKGLTVQVkdsIAEGFAINVDIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRI 288
Cdd:PRK09835 338 --LADEVGK--VFdffeaWAEERGVELRF---VGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQL 410
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 503145266 289 IQTN-----------------------QVRKnsgGESFGIGLKTCEKIAERHEGT 320
Cdd:PRK09835 411 VVENpgtpiapehlprlfdrfyrvdpsRQRK---GEGSGIGLAIVKSIVVAHKGT 462
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
56-238 |
7.24e-06 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 47.26 E-value: 7.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 56 LLSYMVTIAVLFVVFLKLFHKKIRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINEREtaiRE 135
Cdd:COG5000 12 LLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREELE---ER 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 136 NHEMVTAISHdirtpLTSVICYLDliRDGKVkspeeeaVYINNALEKACQIKNLttALFSHSVAENEEVMFHYELIDgnE 215
Cdd:COG5000 89 RRYLETILEN-----LPAGVIVLD--ADGRI-------TLANPAAERLLGIPLE--ELIGKPLEELLPELDLAELLR--E 150
|
170 180
....*....|....*....|...
gi 503145266 216 LLAQVLSESVFLLEEKGLTVQVK 238
Cdd:COG5000 151 ALERGWQEEIELTRDGRRTLLVR 173
|
|
| HAMP |
pfam00672 |
HAMP domain; |
78-124 |
9.38e-06 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 42.23 E-value: 9.38e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 503145266 78 IRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQK 124
Cdd:pfam00672 7 LRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
54-261 |
9.42e-06 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 47.19 E-value: 9.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 54 VELLSYMVTIAVLFVVFLKLFHKKIRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINERETAI 133
Cdd:COG3850 119 LALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEEE 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 134 RENHEMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEAVYINNALEKACQIKNLTTALFSHSVAENEEVMFHYELIDG 213
Cdd:COG3850 199 ELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASAL 278
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 503145266 214 NELLAQVLSESVFLLEEKGLTVQVKDSIAEGFAINVDIQQFRRVFDNL 261
Cdd:COG3850 279 LLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANA 326
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
78-122 |
1.96e-05 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 41.28 E-value: 1.96e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 503145266 78 IRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTL 122
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
250-338 |
5.05e-05 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 41.97 E-value: 5.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 250 DIQQFRRVFDNLCSNALKYADPRRPI----------SFDVM-----LEPDTLRIIQTNQVR-KNSGGESFGIGLKTCEKI 313
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAAKAGEItvtlseggelTLTVEdngigIPPEDLPRIFEPFSTaDKRGGGGTGLGLSIVRKL 81
|
90 100
....*....|....*....|....*...
gi 503145266 314 AERHEGTFksWIEKGE---FVAIWTLPL 338
Cdd:pfam02518 82 VELLGGTI--TVESEPgggTTVTLTLPL 107
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
21-257 |
1.08e-04 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 43.95 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 21 YFGISFVIALASGVATTLLLNCFIRENGISGETVELLSYMVTIAVLFVVFLKLFHKKIRYIHTLEHGIEIIEGGGLEYPI 100
Cdd:COG2770 180 AAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRI 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 101 PVEGDDELTALAIQLNDMRRTLQKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEAVYINNAL 180
Cdd:COG2770 260 PVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLA 339
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503145266 181 EKACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVKDSIAEGFAINVDIQQFRRV 257
Cdd:COG2770 340 LLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLAL 416
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
99-319 |
1.23e-04 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 43.68 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 99 PIPVEGDDELTALAIQLNDMRRTLQ-KQINERetairenheMVTAISHDIRTPLTSVICYLDLIRDGkvKSPEEEAVYIN 177
Cdd:PRK11100 227 PLPKLGSSELRELAQALESMRVKLEgKAYVEQ---------YVQTLTHELKSPLAAIRGAAELLQED--PPPEDRARFTG 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 178 NALEKACQIKNLTTALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVQVKdsiAEGFAINVDIQQFRRV 257
Cdd:PRK11100 296 NILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELVEAREAQAAAKGITLRLR---PDDARVLGDPFLLRQA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 258 FDNLCSNALKYADPRRPISFDVMLEPDTLRIIQTNQ-------------------VRKNSGGESFGIGLKTCEKIAERHE 318
Cdd:PRK11100 373 LGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQgpgipdyalpriferfyslPRPANGRKSTGLGLAFVREVARLHG 452
|
.
gi 503145266 319 G 319
Cdd:PRK11100 453 G 453
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
111-276 |
3.29e-04 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 42.28 E-value: 3.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 111 LAIQLNDMRRTLQKQINERETairenheMVTAISHDIRTPLTSVICYLDLIRDgkVKSPEEEAvyINNALEkacQIKNLT 190
Cdd:PRK10604 194 LGVAFNQMADNINALIASKKQ-------LIDGIAHELRTPLVRLRYRLEMSDN--LSAAESQA--LNRDIG---QLEALI 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 191 TALFSHSVAENEEVMFHYELIDGNELLAQVLSESVFLLEEKGLTVqvkDSIAEGFAINVDIQQFRRVFDNLCSNALKYAD 270
Cdd:PRK10604 260 EELLTYARLDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRL---DTPHQGDYGALDMRLMERVLDNLLNNALRYAH 336
|
....*.
gi 503145266 271 PRRPIS 276
Cdd:PRK10604 337 SRVRVS 342
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
250-320 |
3.53e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 39.37 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 250 DIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRII---------------------QTNQVRKNSGGESfGIGLK 308
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDvedsapgvsddqlarlferfyRVESSRNRASGGS-GLGLA 79
|
90
....*....|..
gi 503145266 309 TCEKIAERHEGT 320
Cdd:cd16946 80 ICHNIALAHGGT 91
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
255-321 |
3.64e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 39.29 E-value: 3.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 255 RRVFDNLCSNALKYADPRRPISFDVMLEPDTLRIIQTNQ----------------VR----KNSGGesFGIGLKTCEKIA 314
Cdd:cd16923 2 QRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPsshpldfkleklferfYRgdnsRNTEG--AGLGLSIAKAII 79
|
....*..
gi 503145266 315 ERHEGTF 321
Cdd:cd16923 80 ELHGGSA 86
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
78-127 |
3.69e-04 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 38.00 E-value: 3.69e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 503145266 78 IRYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQIN 127
Cdd:smart00304 4 LRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
100-320 |
6.13e-04 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 41.37 E-value: 6.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 100 IPVEGDDELTALAIQLNDmrRTLQKQINERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDgkvkspeEEAV-YINN 178
Cdd:COG3290 155 VPIRDDGRVVGAVATFRD--RTELERLEEELEGVKELAEALRAQRHDFRNHLHTISGLLQLGEY-------DEALeYIDE 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 179 ALEkacQIKNLTTALFSHSvaeneevmfhyelidGNELLAQVLSESVFLLEEKG--LTVQVKDSIAEgfaINVDIQQFRR 256
Cdd:COG3290 226 ISE---ELQELIDSLLSRI---------------GNPVLAALLLGKAARARERGidLTIDIDSDLPD---LPLSDTDLVT 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 257 VFDNLCSNAL----KYADPRRPISFDVMLEPDTLRIIQTNQVR-----------------KNSGGEsfGIGLKTCEKIAE 315
Cdd:COG3290 285 ILGNLLDNAIeaveKLPEEERRVELSIRDDGDELVIEVEDSGPgipeellekifergfstKLGEGR--GLGLALVKQIVE 362
|
....*
gi 503145266 316 RHEGT 320
Cdd:COG3290 363 KYGGT 367
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
55-149 |
1.27e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 40.39 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 55 ELLSYMVTIAVLFVVFLKLFHKKI-RYIHTLEHGIEIIEGGGLEYPIPVEGDDELTALAIQLNDMRRTLQKQINEretaI 133
Cdd:COG0840 183 LLAAALLALVALAIILALLLSRSItRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQ----V 258
|
90
....*....|....*.
gi 503145266 134 RENHEMVTAISHDIRT 149
Cdd:COG0840 259 RESAEQVASASEELAA 274
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
138-339 |
1.34e-03 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 40.24 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 138 EMVTAISHDIRTPLTSVICYLDLIRdGKVKSPEEEAVYINNALEKACQIKNLTTALFSHSVAENEevmfHYELIDGNELL 217
Cdd:COG5806 203 ELAASIAHEVRNPLTVVRGFIQLLQ-EPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKPQPE----KLEKIDVSEEL 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 218 AQVLSesvfLLEEKGLT--VQVKDSIAEGFAINVDIQQFRRVFDNLCSNALKYADPRRPISFDVMLEPDTLRII------ 289
Cdd:COG5806 278 EHVID----VLSPYANMnnVEIQTELEPGLYIEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVSIDKNKVIISikdtgv 353
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 503145266 290 -----QTNQVrknsgGESF--------GIGLKTCEKIAERHEGT--FKSWIEKGEFVAIwTLPLY 339
Cdd:COG5806 354 gmtkeQLERL-----GEPYfstkekgtGLGTMVSYRIIEAMNGTirVESEVGKGTTFTI-TLPLA 412
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
14-139 |
1.55e-03 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 40.00 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 14 LGLTIMKYFGISFVIALASGVATTLLLNCFIRENGISGETVELLSYMVTIAVLFVVFLKLFHKKIRY-----IHTLEHGI 88
Cdd:COG2972 113 LLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRsitrpIKRLKKAM 192
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 503145266 89 EIIEGGGLEYpIPVEGDDELTALAIQLNDMRRTLQKQINERETAIRENHEM 139
Cdd:COG2972 193 KKVEKGDLVR-LEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKKEA 242
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
107-270 |
2.83e-03 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 39.50 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 107 ELTALAIQLNDMRRtlqkqinERETAIRENHEMVTAISHDIRTPLTSVICYLDLIRDGKVKSPEEEAVY-INNALEKACQ 185
Cdd:PRK11466 422 ELQELVIEHRQARA-------EAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRaITDSGESLLT 494
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503145266 186 IKN-----LTTALFSHSVAENEEVMFHYELIDGnelLAQVLSESVflleeKGLTVQVKDSIAEGF--AINVDIQQFRRVF 258
Cdd:PRK11466 495 ILNdildySAIEAGGKNVSVSDEPFEPRPLLES---TLQLMSGRV-----KGRPIRLATDIADDLptALMGDPRRIRQVI 566
|
170
....*....|..
gi 503145266 259 DNLCSNALKYAD 270
Cdd:PRK11466 567 TNLLSNALRFTD 578
|
|
| |
