|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
12-433 |
0e+00 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 611.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQ-QGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNET--VETCLYVGL 88
Cdd:PRK10901 3 NLRALAAAAILQVVdQGQSLSAALPALQQKVSDKDRALLQELCYGVLRRLPRLEWLIAQLLAKPLKGKQriVHALLLVGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 89 YQVLCTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRETDDFQQGLQ----QAHGLPSWLFKRLKKDWGEQTESL 164
Cdd:PRK10901 83 YQLLYTRIPAHAAVDETVEAAKALKRPWAKGLVNAVLRRFQREQEELLAELQadpvARYNHPSWLIKRLKKAYPEQWQAI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 165 CQSLKQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILLPD 244
Cdd:PRK10901 163 LAANNQRPPMWLRVNRRHHSRDAYLALLAEAGIEAFPHAVGPDAIRLETPVPVHQLPGFAEGWVSVQDAAAQLAATLLAP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 245 LNNKTVIDACAAPGGKTAHLLEKFKPAQLIAIDQDSNRLIRVTENLNRLALDQsqtEILAADAT---QWVPAEPVDCIVL 321
Cdd:PRK10901 243 QNGERVLDACAAPGGKTAHILELAPQAQVVALDIDAQRLERVRENLQRLGLKA---TVIVGDARdpaQWWDGQPFDRILL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 322 DAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAKEIKi 401
Cdd:PRK10901 320 DAPCSATGVIRRHPDIKWLRRPEDIAALAALQSEILDALWPLLKPGGTLLYATCSILPEENEQQIKAFLARHPDAELLD- 398
|
410 420 430
....*....|....*....|....*....|..
gi 502961538 402 eanWGLEQIHGRQLLPQAQSGDGFYYCKIQKI 433
Cdd:PRK10901 399 ---TGTPQQPGRQLLPGEEDGDGFFYALLIKR 427
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
12-434 |
3.57e-131 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 385.13 E-value: 3.57e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQQGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPL--NNETVETCLYVGLY 89
Cdd:COG0144 17 ALALALLLLALLLLDRALAALLLLAALRLLRRRDRALLAALLAGLLRLLRLLLLLLRLLLLLLLllLLPLLAALLLVAAA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 90 QVLCTRIAAHAAIsetvdatkqlgFPALGGIVNAILRRATRETDDFQQG------LQQAHGLPSWLFKRLKKDWG-EQTE 162
Cdd:COG0144 97 QLLAARVAVDEAV-----------GPGAAGLVNAVLRRVLREREALLAAadpverLAVRYSHPEWLVERLRAAYGpEEAE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 163 SLCQSLKQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILL 242
Cdd:COG0144 166 ALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDGLRLEGPGPVTALPGFREGLFSVQDEASQLVALLL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 243 PDLNNKTVIDACAAPGGKTAHLLEKFKP-AQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADATQWVP--AEPVDCI 319
Cdd:COG0144 246 DPKPGERVLDLCAAPGGKTLHLAELMGNkGRVVAVDISEHRLKRLRENLARLGL--SNVEVVVADARELLEwlPGKFDRV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 320 VLDAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAKEI 399
Cdd:COG0144 324 LLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLLKPGGRLVYSTCSLLPEENEEVVEAFLARHPDFELV 403
|
410 420 430
....*....|....*....|....*....|....*...
gi 502961538 400 KIEANWG---LEQIHGRQLLPQAQSGDGFYYCKIQKIA 434
Cdd:COG0144 404 PLAELLPglaLTDGGYLRLLPHRHGTDGFFIARLRKKA 441
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
14-432 |
4.53e-124 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 366.50 E-value: 4.53e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 14 RAQVVQTLLKVQQGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNE--TVETCLYVGLYQV 91
Cdd:TIGR00563 1 RSIAAQALEQLEQGQSLSNLLPPLQQKVSDQDRALLQELCFGVLRTLSQLDWLIKKLMDRPMKGKprTVHYLILVGLYQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 92 LCTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRETDDFQQ---GLQQAHGLPSWLFKRLKKDWGEQTESLCQSL 168
Cdd:TIGR00563 81 LYTRIPAHAAVAETVEGAKAIKRKGLKGLVNGVLRRFQREQEELLAefnALDARYLHPEWLVKRLQKAYPGQWQSICEAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 169 KQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILLPDLNNK 248
Cdd:TIGR00563 161 NQRPPMWLRINRTKHSRDEWLALLAEAGMKGFPHDLAPDAVRLETPAAVHALPGFEEGWVTVQDASAQWVATWLAPQNEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 249 TVIDACAAPGGKTAHLLEKFKPAQLIAIDQDSNRLIRVTENLNRLALdQSQTEILAADA---TQWVPAEPVDCIVLDAPC 325
Cdd:TIGR00563 241 TILDACAAPGGKTTHILELAPQAQVVALDIHEHRLKRVYENLKRLGL-TIKAETKDGDGrgpSQWAENEQFDRILLDAPC 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 326 SATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAkeiKIEANW 405
Cdd:TIGR00563 320 SATGVIRRHPDIKWLRKPRDIAELAELQSEILDAIWPLLKTGGTLVYATCSVLPEENSEQIKAFLQEHPDF---PFEKTG 396
|
410 420
....*....|....*....|....*....
gi 502961538 406 GLEQIH--GRQLLPQAQSGDGFYYCKIQK 432
Cdd:TIGR00563 397 TPEQVRdgGLQILPHAEEGDGFFYAKLIK 425
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
239-431 |
1.01e-61 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 198.42 E-value: 1.01e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 239 VILLPDLNNKTVIDACAAPGGKTAHLLEKFKP-AQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADATQ---WVPAE 314
Cdd:pfam01189 1 AILLAPQEGETILDMCAAPGGKTTHIAELMKNqGTVVAVDINKHRLKRVAENIHRLGV--TNTIILNGDGRQpdqWLGGV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 315 PVDCIVLDAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHS 394
Cdd:pfam01189 79 LFDRILLDAPCSGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 502961538 395 DAKEIKIEANWGLEQIHG----RQLLPQAQSGDGFYYCKIQ 431
Cdd:pfam01189 159 DVELVPTPLFEPVGLAIGeqptLRLLPHTHNGDGFFIAKLR 199
|
|
| Methyltransferase_Sun |
cd00620 |
N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine ... |
12-131 |
3.12e-21 |
|
N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological role of this domain in Sun is unknown, although it is likely to be involved in sequence-specific RNA binding. The C-terminal methyltransferase domain of Sun has been shown to catalyze formation of m5C at position 967 of 16S rRNA in Escherichia coli.
Pssm-ID: 238343 [Multi-domain] Cd Length: 126 Bit Score: 88.94 E-value: 3.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKV-QQGQSLASILNT-QLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNE--TVETCLYVG 87
Cdd:cd00620 2 NARSTAAEVLRDVlQRGASLNAVLSAlQKKDKSDRDRGLATELVYGTLRWLALLDWIINPLLKKPDVGKdpDVRNLLRLG 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 502961538 88 LYQVLCTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRE 131
Cdd:cd00620 82 LYQLLYLDVPPHAAVDETVEIAKIRKDLGRAGLVNAVLRRFERE 125
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
12-433 |
0e+00 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 611.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQ-QGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNET--VETCLYVGL 88
Cdd:PRK10901 3 NLRALAAAAILQVVdQGQSLSAALPALQQKVSDKDRALLQELCYGVLRRLPRLEWLIAQLLAKPLKGKQriVHALLLVGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 89 YQVLCTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRETDDFQQGLQ----QAHGLPSWLFKRLKKDWGEQTESL 164
Cdd:PRK10901 83 YQLLYTRIPAHAAVDETVEAAKALKRPWAKGLVNAVLRRFQREQEELLAELQadpvARYNHPSWLIKRLKKAYPEQWQAI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 165 CQSLKQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILLPD 244
Cdd:PRK10901 163 LAANNQRPPMWLRVNRRHHSRDAYLALLAEAGIEAFPHAVGPDAIRLETPVPVHQLPGFAEGWVSVQDAAAQLAATLLAP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 245 LNNKTVIDACAAPGGKTAHLLEKFKPAQLIAIDQDSNRLIRVTENLNRLALDQsqtEILAADAT---QWVPAEPVDCIVL 321
Cdd:PRK10901 243 QNGERVLDACAAPGGKTAHILELAPQAQVVALDIDAQRLERVRENLQRLGLKA---TVIVGDARdpaQWWDGQPFDRILL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 322 DAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAKEIKi 401
Cdd:PRK10901 320 DAPCSATGVIRRHPDIKWLRRPEDIAALAALQSEILDALWPLLKPGGTLLYATCSILPEENEQQIKAFLARHPDAELLD- 398
|
410 420 430
....*....|....*....|....*....|..
gi 502961538 402 eanWGLEQIHGRQLLPQAQSGDGFYYCKIQKI 433
Cdd:PRK10901 399 ---TGTPQQPGRQLLPGEEDGDGFFYALLIKR 427
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
12-434 |
3.57e-131 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 385.13 E-value: 3.57e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQQGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPL--NNETVETCLYVGLY 89
Cdd:COG0144 17 ALALALLLLALLLLDRALAALLLLAALRLLRRRDRALLAALLAGLLRLLRLLLLLLRLLLLLLLllLLPLLAALLLVAAA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 90 QVLCTRIAAHAAIsetvdatkqlgFPALGGIVNAILRRATRETDDFQQG------LQQAHGLPSWLFKRLKKDWG-EQTE 162
Cdd:COG0144 97 QLLAARVAVDEAV-----------GPGAAGLVNAVLRRVLREREALLAAadpverLAVRYSHPEWLVERLRAAYGpEEAE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 163 SLCQSLKQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILL 242
Cdd:COG0144 166 ALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDGLRLEGPGPVTALPGFREGLFSVQDEASQLVALLL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 243 PDLNNKTVIDACAAPGGKTAHLLEKFKP-AQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADATQWVP--AEPVDCI 319
Cdd:COG0144 246 DPKPGERVLDLCAAPGGKTLHLAELMGNkGRVVAVDISEHRLKRLRENLARLGL--SNVEVVVADARELLEwlPGKFDRV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 320 VLDAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAKEI 399
Cdd:COG0144 324 LLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLLKPGGRLVYSTCSLLPEENEEVVEAFLARHPDFELV 403
|
410 420 430
....*....|....*....|....*....|....*...
gi 502961538 400 KIEANWG---LEQIHGRQLLPQAQSGDGFYYCKIQKIA 434
Cdd:COG0144 404 PLAELLPglaLTDGGYLRLLPHRHGTDGFFIARLRKKA 441
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
14-432 |
4.53e-124 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 366.50 E-value: 4.53e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 14 RAQVVQTLLKVQQGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNE--TVETCLYVGLYQV 91
Cdd:TIGR00563 1 RSIAAQALEQLEQGQSLSNLLPPLQQKVSDQDRALLQELCFGVLRTLSQLDWLIKKLMDRPMKGKprTVHYLILVGLYQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 92 LCTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRETDDFQQ---GLQQAHGLPSWLFKRLKKDWGEQTESLCQSL 168
Cdd:TIGR00563 81 LYTRIPAHAAVAETVEGAKAIKRKGLKGLVNGVLRRFQREQEELLAefnALDARYLHPEWLVKRLQKAYPGQWQSICEAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 169 KQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILLPDLNNK 248
Cdd:TIGR00563 161 NQRPPMWLRINRTKHSRDEWLALLAEAGMKGFPHDLAPDAVRLETPAAVHALPGFEEGWVTVQDASAQWVATWLAPQNEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 249 TVIDACAAPGGKTAHLLEKFKPAQLIAIDQDSNRLIRVTENLNRLALdQSQTEILAADA---TQWVPAEPVDCIVLDAPC 325
Cdd:TIGR00563 241 TILDACAAPGGKTTHILELAPQAQVVALDIHEHRLKRVYENLKRLGL-TIKAETKDGDGrgpSQWAENEQFDRILLDAPC 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 326 SATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAkeiKIEANW 405
Cdd:TIGR00563 320 SATGVIRRHPDIKWLRKPRDIAELAELQSEILDAIWPLLKTGGTLVYATCSVLPEENSEQIKAFLQEHPDF---PFEKTG 396
|
410 420
....*....|....*....|....*....
gi 502961538 406 GLEQIH--GRQLLPQAQSGDGFYYCKIQK 432
Cdd:TIGR00563 397 TPEQVRdgGLQILPHAEEGDGFFYAKLIK 425
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
12-433 |
1.87e-96 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 296.32 E-value: 1.87e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQQGQSLASI-LNTQLN--QVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNET-VETCLYVG 87
Cdd:PRK14902 4 NARELALEVLIKVENNGAYSNIaLNKVLKksELSDKDKALLTELVYGTIQRKLTLDYYLAPFIKKRKKLDPwVRNLLRMS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 88 LYQVLCT-RIAAHAAISETVDATKQLGFPALGGIVNAILRRATRET-------DDFQQGLQQAHGLPSWLFKRLKKDWG- 158
Cdd:PRK14902 84 LYQLLYLdKVPDHAAVNEAVEIAKKRGHKGIAKFVNGVLRNILREGlpdideiKDPVKRLSIKYSHPVWLVKRWIDQYGe 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 159 EQTESLCQSLKQVAPLTLRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSvQITQLPGFEEGWFSVQDEHAQLC 238
Cdd:PRK14902 164 EKAEKILESLNEPPKASIRVNTLKISVEELIEKLEEEGYEVEESLLSPEALVIEKG-NIAGTDLFKDGLITIQDESSMLV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 239 V-ILLPDlNNKTVIDACAAPGGKTAHLLEKFKP-AQLIAIDQDSNRLIRVTENLNRLALDQSQTEILaaDATQwVP---A 313
Cdd:PRK14902 243 ApALDPK-GGDTVLDACAAPGGKTTHIAELLKNtGKVVALDIHEHKLKLIEENAKRLGLTNIETKAL--DARK-VHekfA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 314 EPVDCIVLDAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEH 393
Cdd:PRK14902 319 EKFDKILVDAPCSGLGVIRRKPDIKYNKTKEDIESLQEIQLEILESVAQYLKKGGILVYSTCTIEKEENEEVIEAFLEEH 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 502961538 394 SDAKEIKIEANWGLEQIHGR-----QLLPQAQSGDGFYYCKIQKI 433
Cdd:PRK14902 399 PEFELVPLQHEKPDELVYEVkdgylQILPNDYGTDGFFIAKLRKK 443
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
37-432 |
5.64e-88 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 274.11 E-value: 5.64e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 37 QLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNE--TVETCLYVGLYQVL-CTRIAAHAAISETVDATKQLG 113
Cdd:PRK14901 29 RKYPLSGADRALVTELVYGCIRRRRTLDAWIDQLGKKPAHKQppDLRWLLHLGLYQLRyMDRIPASAAVNTTVELAKQNG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 114 FPALGGIVNAILRRATRETD---------DFQQGLQQAHGLPSWLFKRLKKDWG-EQTESLCQSLKQVAPLTLRVNQRHI 183
Cdd:PRK14901 109 LGGLAGVVNGILRQYLRAREagdplplpeDPIERLAILHSFPDWLVKLWLEWLGlEEAEQLCKWFNQPPSLDLRINPLRT 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 184 GRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQ-ITQLPGFEEGWFSVQDEHAQLCVILLPDLNNKTVIDACAAPGGKTA 262
Cdd:PRK14901 189 SLEEVQAALAEAGITATPIPGLPQGLRLTGNPGsIRQLPGYEEGWWTVQDRSAQLVAPLLDPQPGEVILDACAAPGGKTT 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 263 HLLEKFK-PAQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADATQWVPAEP-----VDCIVLDAPCSATGVIRRHPD 336
Cdd:PRK14901 269 HIAELMGdQGEIWAVDRSASRLKKLQENAQRLGL--KSIKILAADSRNLLELKPqwrgyFDRILLDAPCSGLGTLHRHPD 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 337 IRlLRQSSD-IAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDakeikieanWGLEQiHGRQL 415
Cdd:PRK14901 347 AR-WRQTPEkIQELAPLQAELLESLAPLLKPGGTLVYATCTLHPAENEAQIEQFLARHPD---------WKLEP-PKQKI 415
|
410
....*....|....*..
gi 502961538 416 LPQAQSGDGFYYCKIQK 432
Cdd:PRK14901 416 WPHRQDGDGFFMAVLRK 432
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
239-431 |
1.01e-61 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 198.42 E-value: 1.01e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 239 VILLPDLNNKTVIDACAAPGGKTAHLLEKFKP-AQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADATQ---WVPAE 314
Cdd:pfam01189 1 AILLAPQEGETILDMCAAPGGKTTHIAELMKNqGTVVAVDINKHRLKRVAENIHRLGV--TNTIILNGDGRQpdqWLGGV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 315 PVDCIVLDAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHS 394
Cdd:pfam01189 79 LFDRILLDAPCSGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 502961538 395 DAKEIKIEANWGLEQIHG----RQLLPQAQSGDGFYYCKIQ 431
Cdd:pfam01189 159 DVELVPTPLFEPVGLAIGeqptLRLLPHTHNGDGFFIAKLR 199
|
|
| PRK14904 |
PRK14904 |
16S rRNA methyltransferase B; Provisional |
12-395 |
8.66e-54 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237858 [Multi-domain] Cd Length: 445 Bit Score: 185.65 E-value: 8.66e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQQG-----QSLASILN-TQLNQVaerDRALFHELVLGTLRQWFALKSISLPLLSKPLNN--ETVETC 83
Cdd:PRK14904 3 TARELALQVLQELETGerksdTLLHRMLErSSLERN---DRALATELVNGVLRYRLQLDFIISRFYHHDLEKaaPVLKNI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 84 LYVGLYQVL-CTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRET---DDFQQGLQQAHGL------PSWLFKRL 153
Cdd:PRK14904 80 LRLGVYQLLfLDRVPRWAAVNECVKLARKYKGEHMAKLVNGVLRNISPETislDEWLKGMPEAERLsllyshPEWLLERW 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 154 KKDWGEQ-TESLCQSLKQvAPLT-LRVNQRHIGRDAYLAKLQSLDIQARACTLSeaGIVLEQSVQITQlPGFEEGWFSVQ 231
Cdd:PRK14904 160 IARYGEErTEAMLSYNNQ-APLFgFRINRLKTTPEKFLAAPADASVTFEKSGLP--NFFLSKDFSLFE-PFLKLGLVSVQ 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 232 DEHAQLCVILLPDLNNKTVIDACAAPGGKTAHLLEKFKPA-QLIAIDQDSNRLIRVTENLNRLALDQSQTeiLAADATQW 310
Cdd:PRK14904 236 NPTQALACLLLNPQPGSTVLDLCAAPGGKSTFMAELMQNRgQITAVDRYPQKLEKIRSHASALGITIIET--IEGDARSF 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 311 VPAEPVDCIVLDAPCSATGVIRRHPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFF 390
Cdd:PRK14904 314 SPEEQPDAILLDAPCTGTGVLGRRAELRWKLTPEKLAELVGLQAELLDHAASLLKPGGVLVYATCSIEPEENELQIEAFL 393
|
....*
gi 502961538 391 AEHSD 395
Cdd:PRK14904 394 QRHPE 398
|
|
| PRK14903 |
PRK14903 |
16S rRNA methyltransferase B; Provisional |
23-401 |
1.77e-49 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 184896 [Multi-domain] Cd Length: 431 Bit Score: 173.91 E-value: 1.77e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 23 KVQQGQSLASILNTQLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNETVETCLYVGLYQVLCT-RIAAHAA 101
Cdd:PRK14903 16 YEKEKFIFREDVDSVLSFLDDKDRRFFKELVWGVVRKEELLDWYINQLLKKKDIPPAVRVALRMGAYQLLFMnSVPDYAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 102 ISETVDATKQLGFPalgGIVNAILRRATRETDDFQQGLQQAHglPSWLFKRLKKDWGEqtESLCQSLK---QVAPLTLRV 178
Cdd:PRK14903 96 VSETVKLVKNENFK---KLVNAVLRRLRTVPEPKELHLKYSH--PKWLVNYWRSFLPE--EAVLRIMEwnqEPLPTMLRV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 179 NQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQ-SVQITQLPGFEEGWFSVQDEHAQLCVILLPDLNNKTVIDACAAP 257
Cdd:PRK14903 169 NSLAITREEVIKILAEEGTEAVPGKHSPFSLIVRKlGVNMNDSRVIKDGLATVQGESSQIVPLLMELEPGLRVLDTCAAP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 258 GGKTAHLLEKFKP-AQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADA---TQWVPAEpVDCIVLDAPCSATGVIRR 333
Cdd:PRK14903 249 GGKTTAIAELMKDqGKILAVDISREKIQLVEKHAKRLKL--SSIEIKIADAerlTEYVQDT-FDRILVDAPCTSLGTARN 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502961538 334 HPDIrLLRQS-SDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEQQMINFFAEHSDAKEIKI 401
Cdd:PRK14903 326 HPEV-LRRVNkEDFKKLSEIQLRIVSQAWKLLEKGGILLYSTCTVTKEENTEVVKRFVYEQKDAEVIDI 393
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
176-432 |
1.58e-29 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 115.64 E-value: 1.58e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 176 LRVNQRHIGRDAYLAKLQSLDIQARACTLSEAGIVLEQSVQITQLPGFEEGWFSVQDEHAQLCVILLPDLNNKTVIDACA 255
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVLEPTCEEYFFEVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPREDERVLDMAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 256 APGGKTAHLLEKFK-PAQLIAIDQDSNRLIRVTENLNRLALdqSQTEILAADATQWVPAEP-VDCIVLDAPCSATGVIRR 333
Cdd:TIGR00446 81 APGGKTTQISQLMKnKGCIVANEISKSRTKALISNINRMGV--LNTIVINADGRKFGAYLLkFDAILLDAPCSGEGVIRK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 334 HPDIRLLRQSSDIAQTIELQKQILEHMWQQLNVGGTLLYITCSVLKAENEqQMINFFAEHSDAKEIKIE-------ANWG 406
Cdd:TIGR00446 159 DPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENE-EVIDYILRKRPDVVEEIIkgdeffgINIG 237
|
250 260
....*....|....*....|....*..
gi 502961538 407 LEQIHG-RQLLPQAQSGDGFYYCKIQK 432
Cdd:TIGR00446 238 KGEVKGaLRVFPQNYDCEGFFVAKLRK 264
|
|
| Methyltransferase_Sun |
cd00620 |
N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine ... |
12-131 |
3.12e-21 |
|
N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological role of this domain in Sun is unknown, although it is likely to be involved in sequence-specific RNA binding. The C-terminal methyltransferase domain of Sun has been shown to catalyze formation of m5C at position 967 of 16S rRNA in Escherichia coli.
Pssm-ID: 238343 [Multi-domain] Cd Length: 126 Bit Score: 88.94 E-value: 3.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKV-QQGQSLASILNT-QLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNE--TVETCLYVG 87
Cdd:cd00620 2 NARSTAAEVLRDVlQRGASLNAVLSAlQKKDKSDRDRGLATELVYGTLRWLALLDWIINPLLKKPDVGKdpDVRNLLRLG 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 502961538 88 LYQVLCTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRE 131
Cdd:cd00620 82 LYQLLYLDVPPHAAVDETVEIAKIRKDLGRAGLVNAVLRRFERE 125
|
|
| NusB |
pfam01029 |
NusB family; The NusB protein is involved in the regulation of rRNA biosynthesis by ... |
12-130 |
4.62e-16 |
|
NusB family; The NusB protein is involved in the regulation of rRNA biosynthesis by transcriptional antitermination.
Pssm-ID: 460031 [Multi-domain] Cd Length: 133 Bit Score: 74.61 E-value: 4.62e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQQGQSLAS----ILNTQLNQV-----AERDRALFHELVLGTLRQWFALKS-ISLPLLSKPLN--NET 79
Cdd:pfam01029 2 NARELALQALYQVEINGSDEEekgaYLNEALDKAlegdlSEEDRAFATELVYGVLRNLEELDAlIEKLLENWPLErlSPV 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 502961538 80 VETCLYVGLYQVL-CTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATR 130
Cdd:pfam01029 82 DRAILRLGLYELLfLDDVPPHVAINEAVELAKKFGGEKSAKFVNGVLRNVAR 133
|
|
| NusB_Sun |
cd00447 |
RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or ... |
12-131 |
1.21e-12 |
|
RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the rRNA-specific 5-methylcytidine transferase (m5C-methyltransferase) Sun. The NusB protein plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus factors (NusA, NusE/S10 and NusG) forms the core complex with the boxA element of the nut site of the rRNA operons. These interactions help RNA polymerase to counteract polarity during transcription of rRNA operons and allow stable antitermination. The transcription antitermination system can be appropriated by some bacteriophages such as lambda, which use the system to switch between the lysogenic and lytic modes of phage propagation. The m5C-methyltransferase Sun shares the N-terminal non-catalytic RNA-binding domain with NusB.
Pssm-ID: 238253 [Multi-domain] Cd Length: 129 Bit Score: 64.68 E-value: 1.21e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 12 NLRAQVVQTLLKVQQGQ--SLASILNT-QLNQVAERDRALFHELVLGTLRQWFALKSISLPLLSKPLNNETVETCLYV-- 86
Cdd:cd00447 1 SAREIAFQALYQVEIRNgiSLEAVLSAlEKLQLAKKDRPFALELVYGVLRNLPELDDIISPLLKKWLLDRLDKVDRAIlr 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 502961538 87 ----GLYQVLcTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRE 131
Cdd:cd00447 81 lllyELYQLL-YDVPPPVAINEAVELAKRFGDDDSAKFVNGVLRRIAKE 128
|
|
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
173-399 |
2.61e-12 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 68.40 E-value: 2.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 173 PL--TLRVNQRHIGRDAYLAKLQsldiqaractlseagivlEQSVQITQLPGFEEG-WFSVQD----------EHAQ-LC 238
Cdd:PRK11933 32 PLrrSIRVNTLKISVADFLQLMA------------------PYGWTLTPIPWCEEGfWIERDDedalplgntaEHLSgLF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 239 VI-----LLP-------DLNNKTVIDACAAPGGKTAHLLEKFKPAQLI-AIDQDSNRLIRVTENLNRLALdqSQTEILAA 305
Cdd:PRK11933 94 YIqeassMLPvaalfadDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIvANEYSASRVKVLHANISRCGV--SNVALTHF 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 306 DAT---QWVPaEPVDCIVLDAPCSATGVIRRHPD-IRLLRQSS--DIAQTielQKQILEHMWQQLNVGGTLLYITCSVLK 379
Cdd:PRK11933 172 DGRvfgAALP-ETFDAILLDAPCSGEGTVRKDPDaLKNWSPESnlEIAAT---QRELIESAFHALKPGGTLVYSTCTLNR 247
|
250 260
....*....|....*....|.
gi 502961538 380 AENeQQMINFF-AEHSDAKEI 399
Cdd:PRK11933 248 EEN-QAVCLWLkETYPDAVEF 267
|
|
| NusB |
COG0781 |
Transcription antitermination protein NusB [Transcription]; |
17-131 |
3.70e-11 |
|
Transcription antitermination protein NusB [Transcription];
Pssm-ID: 440544 [Multi-domain] Cd Length: 128 Bit Score: 60.16 E-value: 3.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 17 VVQTLLKVQQ-GQSLASILNTQL--NQVAERDRALFHELVLGTLRQWFALKSISLPLLSK-PLN--NETVETCLYVGLYQ 90
Cdd:COG0781 3 ALQALYQVELsGAYANEILEEFLedEELSEADRAFATELVYGVLRNQEELDALIAPYLKDwPLErlDPVDRAILRLAAYE 82
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 502961538 91 VL-CTRIAAHAAISETVDATKQLGFPALGGIVNAILRRATRE 131
Cdd:COG0781 83 LLyLDDVPYKVAINEAVELAKKFGTEDSPKFVNGVLDKIAKE 124
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
249-371 |
1.48e-07 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 49.05 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 249 TVIDACAAPGGKTAHLLEKFKPAQLIAIDQDSNRLIRVTENLNRLaldqsqtEILAADATQWVPAEPVDCIVldapcsat 328
Cdd:COG4106 4 RVLDLGCGTGRLTALLAERFPGARVTGVDLSPEMLARARARLPNV-------RFVVADLRDLDPPEPFDLVV-------- 68
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 502961538 329 gvirrhpdirllrqSSDIAQTIELQKQILEHMWQQLNVGGTLL 371
Cdd:COG4106 69 --------------SNAALHWLPDHAALLARLAAALAPGGVLA 97
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
249-373 |
1.26e-05 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 43.96 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 249 TVIDACAAPGGKTAHLLEkFKPAQLIAIDQDSnRLIRVTENLNRLALDQsQTEILAADATQWVPA--EPVDCIVLDAPCS 326
Cdd:cd02440 1 RVLDLGCGTGALALALAS-GPGARVTGVDISP-VALELARKAAAALLAD-NVEVLKGDAEELPPEadESFDVIISDPPLH 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 502961538 327 ATGvirrhpdirllrqssdiaqtiELQKQILEHMWQQLNVGGTLLYI 373
Cdd:cd02440 78 HLV---------------------EDLARFLEEARRLLKPGGVLVLT 103
|
|
| Methyltransf_5 |
pfam01795 |
MraW methylase family; Members of this family are probably SAM dependent methyltransferases ... |
238-322 |
1.74e-03 |
|
MraW methylase family; Members of this family are probably SAM dependent methyltransferases based on Swiss:P18595. This family appears to be related to pfam01596.
Pssm-ID: 396387 Cd Length: 309 Bit Score: 40.01 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 238 CVILLPDLNNKTVIDACAAPGGKTAHLLEKFKPAQLIAIDQDSNRLIRVTENL----NRLALDQSQTEILAAdATQWVPA 313
Cdd:pfam01795 12 TVDLLNPKPDGVYIDCTLGGGGHSEAILEQLPELRLIGIDRDPQAIARAKERLkpfeDRVTLVHGNFRFFKE-ALAELGV 90
|
....*....
gi 502961538 314 EPVDCIVLD 322
Cdd:pfam01795 91 TKVDGILLD 99
|
|
| FtsJ |
pfam01728 |
FtsJ-like methyltransferase; This family consists of FtsJ from various bacterial and archaeal ... |
246-393 |
2.95e-03 |
|
FtsJ-like methyltransferase; This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesized that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.
Pssm-ID: 426399 Cd Length: 179 Bit Score: 38.34 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502961538 246 NNKTVIDACAAPGGKTAHLLEKfKPAQLIAID---------QDSNRLIRVTENLNRLALDQSQTEILaadatqwvpAEPV 316
Cdd:pfam01728 21 PGKTVLDLGAAPGGWSQVALQR-GAGKVVGVDlgpmqlwkpRNDPGVTFIQGDIRDPETLDLLEELL---------GRKV 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 502961538 317 DCIVLDApcsatgvirrHPDIRLLRQsSDIAQTIELQKQILEHMWQQLNVGGTLLyitCSVLKAENEQQMINFFAEH 393
Cdd:pfam01728 91 DLVLSDG----------SPFISGNKV-LDHLRSLDLVKAALEVALELLRKGGNFV---CKVFQGEDFSELLYLLKLG 153
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|
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