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Conserved domains on  [gi|502612506|ref|WP_012849478|]
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MULTISPECIES: twin-arginine translocase subunit TatE [Edwardsiella]

Protein Classification

Sec-independent protein translocase family protein( domain architecture ID 241)

Sec-independent protein translocase family protein such as Sec-independent protein translocase proteins TatA and TatB, which are part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Gene Ontology:  GO:0033281|GO:0043953

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TatA_B_E super family cl00788
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 1-66 3.56e-24

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


The actual alignment was detected with superfamily member PRK01614:

Pssm-ID: 445098  Cd Length: 85  Bit Score: 86.10  E-value: 3.56e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPaAKKSDGAEAAPRVENKE 66
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDE-VSTSVLGETKMSAETKT 65
 
Name Accession Description Interval E-value
tatE PRK01614
Sec-independent protein translocase subunit TatA;
1-66 3.56e-24

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 86.10  E-value: 3.56e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPaAKKSDGAEAAPRVENKE 66
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDE-VSTSVLGETKMSAETKT 65
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-47 3.45e-14

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 59.54  E-value: 3.45e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 502612506   3 GISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDET 47
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEE 45
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-66 2.52e-13

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 58.02  E-value: 2.52e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSDGAEAAPRVENKE 66
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEA 66
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-54 1.37e-07

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 43.06  E-value: 1.37e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 502612506   4 ISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSD 54
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEA 51
 
Name Accession Description Interval E-value
tatE PRK01614
Sec-independent protein translocase subunit TatA;
1-66 3.56e-24

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 86.10  E-value: 3.56e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPaAKKSDGAEAAPRVENKE 66
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDE-VSTSVLGETKMSAETKT 65
tatE PRK03625
twin-arginine translocase subunit TatE;
1-66 7.06e-24

twin-arginine translocase subunit TatE;


Pssm-ID: 179612  Cd Length: 67  Bit Score: 84.43  E-value: 7.06e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSDGAEA-APRVENKE 66
Cdd:PRK03625  1 MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDAAAKKGADVDLqAEKLSHKE 67
tatA PRK04598
twin-arginine translocase subunit TatA;
1-66 2.73e-22

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 81.06  E-value: 2.73e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSDGAEAAPRVENKE 66
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESAKANKKDADFEPKNLEQA 66
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-53 1.51e-17

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 69.32  E-value: 1.51e-17
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKS 53
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKT 53
tatA PRK01833
Sec-independent protein translocase subunit TatA;
1-66 4.20e-17

Sec-independent protein translocase subunit TatA;


Pssm-ID: 167284  Cd Length: 74  Bit Score: 67.60  E-value: 4.20e-17
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETP--AAKKSDGAEAAPRVENKE 66
Cdd:PRK01833  1 MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADDKPkdAEFEKVEAKEAASTEQKA 68
tatA PRK02958
Sec-independent protein translocase subunit TatA;
1-66 2.85e-16

Sec-independent protein translocase subunit TatA;


Pssm-ID: 235091  Cd Length: 73  Bit Score: 65.37  E-value: 2.85e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDET---PAAKKSDGAEAAPRVENKE 66
Cdd:PRK02958  1 MGSFSIWHWLIVLVIVVLVFGTKKLRNIGSDLGGAVKGFKDGMKEGEtpqEAQAQQLPDSGTIDVEAKE 69
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
10-64 7.53e-16

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 64.90  E-value: 7.53e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 502612506 10 LVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDET----PAAKKSDGAEAAPRVEN 64
Cdd:PRK00442 10 IVILVVVVLVFGTKKLKNLGSDVGESIKGFRKAMNEDEkedkPAEQPAPPAQPVPPVQN 68
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-47 3.45e-14

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 59.54  E-value: 3.45e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 502612506   3 GISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDET 47
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEE 45
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-66 2.52e-13

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 58.02  E-value: 2.52e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSDGAEAAPRVENKE 66
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEA 66
tatA PRK04561
twin arginine translocase protein A; Provisional
 1-59 6.53e-09

twin arginine translocase protein A; Provisional


Pssm-ID: 179864  Cd Length: 75  Bit Score: 46.83  E-value: 6.53e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDE-TPAAKKSDGAEAA 59
Cdd:PRK04561  1 MGSFSIWHWLVVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDdKPAGQLGDDSRSA 60
tatA PRK00720
twin-arginine translocase TatA/TatE family subunit;
1-65 4.10e-08

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234822  Cd Length: 78  Bit Score: 45.03  E-value: 4.10e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMND-ETPAAKKsdgAEAAPRVENK 65
Cdd:PRK00720  1 MGSFSIWHWLIVLAVVLLLFGRGKISELMGDVAKGIKSFKKGMADdDAPPAEP---PEPVRTIDHK 63
tatA PRK14859
twin arginine translocase protein A; Provisional
 1-60 4.48e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 44.33  E-value: 4.48e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSDGAEAAP 60
Cdd:PRK14859  1 MFGIGMPELIVILVIVLIVFGAGKLPEIGGGLGKSIKNFKKATSEKEEIEIKPTKKEDKK 60
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-61 7.52e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 43.95  E-value: 7.52e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAK-KSDGAEAAPR 61
Cdd:PRK14860  1 MFGFGMPELIVILVIALVVFGPAKLPQLGQALGGAIRNFKKASNEEDVVTInNEKGKEDQAR 62
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-54 1.37e-07

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 43.06  E-value: 1.37e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 502612506   4 ISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSD 54
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEA 51
tatA PRK01470
twin arginine translocase protein A; Provisional
 3-52 3.24e-07

twin arginine translocase protein A; Provisional


Pssm-ID: 179298  Cd Length: 51  Bit Score: 42.15  E-value: 3.24e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 502612506  3 GISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKK 52
Cdd:PRK01470  2 GMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDNDK 51
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
3-45 5.56e-07

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 42.40  E-value: 5.56e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 502612506  3 GISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMND 45
Cdd:PRK14857  5 GIGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEASKE 47
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-64 5.88e-06

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 39.72  E-value: 5.88e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFK---KAMNDETPAAKKSDGAEAAPRVEN 64
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKsevKEMQSDNKAEASAAAAQAPYQVAT 67
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-54 2.02e-05

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 37.64  E-value: 2.02e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 502612506  1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKA----MNDETPAAKKSD 54
Cdd:PRK14861  2 FSNIGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKAtkelTDDDFQEKKKKE 59
tatA PRK00191
twin arginine translocase protein A; Provisional
 7-49 7.21e-05

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 36.86  E-value: 7.21e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 502612506  7 TKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFK---KAMN--DETPA 49
Cdd:PRK00191  6 WEIGIIVLLIIVLFGAKKLPDAARSIGRSMRIFKsevKEMSkdDQTPE 53
tatA PRK14858
twin arginine translocase protein A; Provisional
 1-45 2.58e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 33.30  E-value: 2.58e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 502612506   1 MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMND 45
Cdd:PRK14858   1 MFGIGMPELIVILVIALIVIGPQKLPDLARSLGRGLAEFKKATDD 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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