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Conserved domains on  [gi|502612500|ref|WP_012849472|]
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MULTISPECIES: peptidoglycan glycosyltransferase MrdB [Edwardsiella]

Protein Classification

rod shape-determining protein RodA( domain architecture ID 10013646)

rod shape-determining protein RodA is a peptidoglycan polymerase that is essential for cell wall elongation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10794 PRK10794
rod shape-determining protein RodA;
1-370 0e+00

rod shape-determining protein RodA;


:

Pssm-ID: 182737  Cd Length: 370  Bit Score: 672.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   1 MTENQQKRSIWAKMHIDLPFLLCILAVLVYSAVVMWSASGQDVGMMERKIGQIVMGLLVMIVMAQIPPRVYEHWAPYLYI 80
Cdd:PRK10794   1 MTDNPNKKTFWDKIHIDPTMLLIILALLVYSALVIWSASGQDIGMMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  81 LCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINRDVCPPSLKHTGIALILIFLPTLLVAAQPDL 160
Cdd:PRK10794  81 ICIILLVAVDAFGQISKGAQRWLDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 161 GTSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGL 240
Cdd:PRK10794 161 GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPESDPLGAGYHIIQSKIAIGSGGL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 241 SGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFV 320
Cdd:PRK10794 241 RGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVGVLILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFV 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 502612500 321 NIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKNL 370
Cdd:PRK10794 321 NIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV 370
 
Name Accession Description Interval E-value
PRK10794 PRK10794
rod shape-determining protein RodA;
1-370 0e+00

rod shape-determining protein RodA;


Pssm-ID: 182737  Cd Length: 370  Bit Score: 672.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   1 MTENQQKRSIWAKMHIDLPFLLCILAVLVYSAVVMWSASGQDVGMMERKIGQIVMGLLVMIVMAQIPPRVYEHWAPYLYI 80
Cdd:PRK10794   1 MTDNPNKKTFWDKIHIDPTMLLIILALLVYSALVIWSASGQDIGMMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  81 LCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINRDVCPPSLKHTGIALILIFLPTLLVAAQPDL 160
Cdd:PRK10794  81 ICIILLVAVDAFGQISKGAQRWLDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 161 GTSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGL 240
Cdd:PRK10794 161 GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPESDPLGAGYHIIQSKIAIGSGGL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 241 SGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFV 320
Cdd:PRK10794 241 RGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVGVLILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFV 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 502612500 321 NIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKNL 370
Cdd:PRK10794 321 NIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV 370
rodA_shape TIGR02210
rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family ...
17-364 6.90e-166

rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


Pssm-ID: 274033  Cd Length: 352  Bit Score: 467.37  E-value: 6.90e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   17 DLPFLLCILAVLVYSAVVMWSASGQDVGMMERK-IGQIVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDAFGQI 95
Cdd:TIGR02210   1 DWGLLLLVLLLVGIGLLVLYSASGGSLAPFALKqLVWFGIGLVLMIIVALIDYRFLRRLAYPLYVLGLLLLVAVLLFGTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   96 SKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINRD--VCPPSLKHTGIALILIFLPTLLVAAQPDLGTSILVAASGLFI 173
Cdd:TIGR02210  81 GKGAQRWIDLGFFRLQPSEFAKLALILMLAKYLSRRplDKPPRLKDLLKALILILVPALLILKQPDLGTALVVLAIGLFV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  174 LFLAGMSWRLIGLAVLLVAAFIP-VLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLSGKGWLHGTQSQ 252
Cdd:TIGR02210 161 LFLAGLSWKLILGLLAAGAAAIPvIIWWFLLHDYQKQRILTFLDPESDPLGAGYHIIQSKIAIGSGGLFGKGWLQGTQSQ 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  253 LEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFVNIGMVSGILPVV 332
Cdd:TIGR02210 241 LEFLPEQHTDFIFSVLAEEFGFVGGLVLLLLYLLLILRGLRIALNAKDRFGRLLAGGIALTFFFYVFVNIGMVIGLLPVV 320
                         330       340       350
                  ....*....|....*....|....*....|..
gi 502612500  333 GVPLPLVSYGGSALIVLMAGFGIVMSIHTHRK 364
Cdd:TIGR02210 321 GIPLPLVSYGGSSLLTLMIGFGLLMSIHTHRR 352
FtsW COG0772
Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome ...
7-365 5.04e-125

Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440535  Cd Length: 371  Bit Score: 364.43  E-value: 5.04e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   7 KRSIWAKMHIDLPFLLCILAVLVYSAVVMWSASGQDV--------GMMERKIGQIVMGLLVMIVMAQIPPRVYEHWAPYL 78
Cdd:COG0772    4 GLLLRRLRKIDWLLLLLVLLLLGIGLVMVYSASSALAarkggdpfYFFKRQLIWLLLGLVLMLVVSRIDYRRLRRLAYPL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  79 YILCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFI-NRDVCPPSLKHTGIALILIFLPTLLVAAQ 157
Cdd:COG0772   84 YLLGLVLLLLVLLFGTEVNGARRWISLGGFSFQPSEFAKLALILFLASYLsRKRDKLKDLKGLLPPLLLIGLPVGLILLQ 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 158 PDLGTSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLwfFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGS 237
Cdd:COG0772  164 PDLGTALVLFAIFLGMLFVAGLPWKYLLGLLLLGVAAAVLL--ILLKPYQRARILAFLDPWADPLGAGYQIIQSLIAIGS 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 238 GGLSGKGWLHGTQsQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVY 317
Cdd:COG0772  242 GGLFGKGLGNGTQ-KLGYLPEAHTDFIFAVIGEELGFIGALLVLLLFLLLIYRGLRIALRARDPFGRLLAAGIASLIFFQ 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 502612500 318 VFVNIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKM 365
Cdd:COG0772  321 AFINIGMVTGLLPVTGVPLPFISYGGSSLLANMIALGLLLSISRRRRR 368
FTSW_RODA_SPOVE pfam01098
Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE
20-364 2.54e-119

Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE


Pssm-ID: 426047  Cd Length: 356  Bit Score: 349.25  E-value: 2.54e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   20 FLLCILAVLVYSAVVMWSASG-QDVGMME-------RKIGQIVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDA 91
Cdd:pfam01098   4 LFIVLLLLGALGLVMVYSASAvTSLVLFGdsffffkRQLVYLLLGFIAFWVLLRIPLRFLRKWAFYLFIIGLLLLVLVFV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   92 FGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINR--DVCPPSLKHTGIALILIFLPTLLVAAQPDLGTSILVAAS 169
Cdd:pfam01098  84 IGPSANGAKRWIRLGGFSIQPSEFMKIALTLFLAAYLSRkpDNVRPRLRGFLPPLVIIALAAGLILLQPDLGTAVLLGII 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  170 GLFILFLAGMSWRLIGLAVLLvaAFIPVLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLSGKGWLHGT 249
Cdd:pfam01098 164 LLVMLFLSGLSWRLFIALVLI--GVSPIVWLILLEDYQIKRVTSFLDPFKDPLGSGYQIIQSLIAIGSGGIFGKGLGNGQ 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  250 QsQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFVNIGMVSGIL 329
Cdd:pfam01098 242 Q-KLGYLPEAHTDFIFAVIGEELGFVGVLILLALFGLLIYRGLRIARRARDRFGSLLAVGISLLIFIQSFINIGMVSGLL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 502612500  330 PVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRK 364
Cdd:pfam01098 321 PVTGLPLPFFSYGGSSLLATLALFGILLNISRELR 355
RodA_shape NF037961
rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE ...
53-359 1.00e-56

rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE superfamily. It has been reported that RodA proteins play important roles in maintaining cell shape and antibiotic resistance in bacteria.


Pssm-ID: 411566  Cd Length: 415  Bit Score: 190.50  E-value: 1.00e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  53 IVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARF---IN 129
Cdd:NF037961  45 IGLSFVLIILILAIEAKFYERFSSIIYIISLLSLLGLFIFGKTINGATSWYAIGGFTLQPSEFAKAATALALAKYlsdIQ 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 130 RDVcpPSLKHTGIALILIFLPTLLVAAQPDLGtSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLWF--------- 200
Cdd:NF037961 125 TDI--KRFKDQLKAFAIILIPAILILLQPDAG-SALVYFAFFFVLYREGLPLIYLIIGFILILLFVLTLKFgpiwvliia 201
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 201 ---FLMHDY-------------------------------------QRDRVMMLLDPESDPL-------GAGYHIIQSKI 233
Cdd:NF037961 202 allIFLYYFlkkkkkppilkiiiillicilfsfsvnfvydnvleqhHRDRFSLWLGLEKDPEkleqmkkTIGYNTNQSEK 281
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 234 AIGSGGLSGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLI 313
Cdd:NF037961 282 AISSGGFTGKGFLEGTRTKGNFVPEQHTDYIFSTVGEEWGFLGSSLVVLLFVLLLLRIIYLAERQKSQFSRVYGYSVASI 361
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 502612500 314 LFVYVFVNIGMVSGILPVVGVPLPLVSYGGSALIvlmaGFGIVMSI 359
Cdd:NF037961 362 LFIHFFINIGMVIGLIPTIGIPLPFFSYGGSGLW----GFTILLFI 403
 
Name Accession Description Interval E-value
PRK10794 PRK10794
rod shape-determining protein RodA;
1-370 0e+00

rod shape-determining protein RodA;


Pssm-ID: 182737  Cd Length: 370  Bit Score: 672.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   1 MTENQQKRSIWAKMHIDLPFLLCILAVLVYSAVVMWSASGQDVGMMERKIGQIVMGLLVMIVMAQIPPRVYEHWAPYLYI 80
Cdd:PRK10794   1 MTDNPNKKTFWDKIHIDPTMLLIILALLVYSALVIWSASGQDIGMMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  81 LCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINRDVCPPSLKHTGIALILIFLPTLLVAAQPDL 160
Cdd:PRK10794  81 ICIILLVAVDAFGQISKGAQRWLDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 161 GTSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGL 240
Cdd:PRK10794 161 GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPESDPLGAGYHIIQSKIAIGSGGL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 241 SGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFV 320
Cdd:PRK10794 241 RGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVGVLILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFV 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 502612500 321 NIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKNL 370
Cdd:PRK10794 321 NIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV 370
rodA_shape TIGR02210
rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family ...
17-364 6.90e-166

rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


Pssm-ID: 274033  Cd Length: 352  Bit Score: 467.37  E-value: 6.90e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   17 DLPFLLCILAVLVYSAVVMWSASGQDVGMMERK-IGQIVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDAFGQI 95
Cdd:TIGR02210   1 DWGLLLLVLLLVGIGLLVLYSASGGSLAPFALKqLVWFGIGLVLMIIVALIDYRFLRRLAYPLYVLGLLLLVAVLLFGTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   96 SKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINRD--VCPPSLKHTGIALILIFLPTLLVAAQPDLGTSILVAASGLFI 173
Cdd:TIGR02210  81 GKGAQRWIDLGFFRLQPSEFAKLALILMLAKYLSRRplDKPPRLKDLLKALILILVPALLILKQPDLGTALVVLAIGLFV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  174 LFLAGMSWRLIGLAVLLVAAFIP-VLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLSGKGWLHGTQSQ 252
Cdd:TIGR02210 161 LFLAGLSWKLILGLLAAGAAAIPvIIWWFLLHDYQKQRILTFLDPESDPLGAGYHIIQSKIAIGSGGLFGKGWLQGTQSQ 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  253 LEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFVNIGMVSGILPVV 332
Cdd:TIGR02210 241 LEFLPEQHTDFIFSVLAEEFGFVGGLVLLLLYLLLILRGLRIALNAKDRFGRLLAGGIALTFFFYVFVNIGMVIGLLPVV 320
                         330       340       350
                  ....*....|....*....|....*....|..
gi 502612500  333 GVPLPLVSYGGSALIVLMAGFGIVMSIHTHRK 364
Cdd:TIGR02210 321 GIPLPLVSYGGSSLLTLMIGFGLLMSIHTHRR 352
FtsW COG0772
Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome ...
7-365 5.04e-125

Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440535  Cd Length: 371  Bit Score: 364.43  E-value: 5.04e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   7 KRSIWAKMHIDLPFLLCILAVLVYSAVVMWSASGQDV--------GMMERKIGQIVMGLLVMIVMAQIPPRVYEHWAPYL 78
Cdd:COG0772    4 GLLLRRLRKIDWLLLLLVLLLLGIGLVMVYSASSALAarkggdpfYFFKRQLIWLLLGLVLMLVVSRIDYRRLRRLAYPL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  79 YILCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFI-NRDVCPPSLKHTGIALILIFLPTLLVAAQ 157
Cdd:COG0772   84 YLLGLVLLLLVLLFGTEVNGARRWISLGGFSFQPSEFAKLALILFLASYLsRKRDKLKDLKGLLPPLLLIGLPVGLILLQ 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 158 PDLGTSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLwfFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGS 237
Cdd:COG0772  164 PDLGTALVLFAIFLGMLFVAGLPWKYLLGLLLLGVAAAVLL--ILLKPYQRARILAFLDPWADPLGAGYQIIQSLIAIGS 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 238 GGLSGKGWLHGTQsQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVY 317
Cdd:COG0772  242 GGLFGKGLGNGTQ-KLGYLPEAHTDFIFAVIGEELGFIGALLVLLLFLLLIYRGLRIALRARDPFGRLLAAGIASLIFFQ 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 502612500 318 VFVNIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKM 365
Cdd:COG0772  321 AFINIGMVTGLLPVTGVPLPFISYGGSSLLANMIALGLLLSISRRRRR 368
FTSW_RODA_SPOVE pfam01098
Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE
20-364 2.54e-119

Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE


Pssm-ID: 426047  Cd Length: 356  Bit Score: 349.25  E-value: 2.54e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   20 FLLCILAVLVYSAVVMWSASG-QDVGMME-------RKIGQIVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDA 91
Cdd:pfam01098   4 LFIVLLLLGALGLVMVYSASAvTSLVLFGdsffffkRQLVYLLLGFIAFWVLLRIPLRFLRKWAFYLFIIGLLLLVLVFV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   92 FGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINR--DVCPPSLKHTGIALILIFLPTLLVAAQPDLGTSILVAAS 169
Cdd:pfam01098  84 IGPSANGAKRWIRLGGFSIQPSEFMKIALTLFLAAYLSRkpDNVRPRLRGFLPPLVIIALAAGLILLQPDLGTAVLLGII 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  170 GLFILFLAGMSWRLIGLAVLLvaAFIPVLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLSGKGWLHGT 249
Cdd:pfam01098 164 LLVMLFLSGLSWRLFIALVLI--GVSPIVWLILLEDYQIKRVTSFLDPFKDPLGSGYQIIQSLIAIGSGGIFGKGLGNGQ 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  250 QsQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFVNIGMVSGIL 329
Cdd:pfam01098 242 Q-KLGYLPEAHTDFIFAVIGEELGFVGVLILLALFGLLIYRGLRIARRARDRFGSLLAVGISLLIFIQSFINIGMVSGLL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 502612500  330 PVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRK 364
Cdd:pfam01098 321 PVTGLPLPFFSYGGSSLLATLALFGILLNISRELR 355
ftsW TIGR02614
cell division protein FtsW; This family consists of FtsW, an integral membrane protein with ...
21-363 4.22e-78

cell division protein FtsW; This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


Pssm-ID: 274232  Cd Length: 356  Bit Score: 244.01  E-value: 4.22e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   21 LLCILAVLVYSAVVMWSAS--GQDVGMMERKIGQIVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDAF--GQIS 96
Cdd:TIGR02614  11 LLGIGLVMVYSASAAVALRlgGNPFYFLKRQLFYALLGLILMFVASRLPLRFWRKLSVPILLIAIVLLVLVLIPgiGKEV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500   97 KGAQRWLDLGFVRFQPSEIAKIAVPLMVARFI--NRDVCPPSLKHTGIALILIFLPTLLVAAQPDLGTSILVAASGLFIL 174
Cdd:TIGR02614  91 NGARRWIGLGGFSIQPSEFAKLALIIYLAWYLarKQKEVKSFLKFLPPLAVLGLLVGLLLLLQPDFGTTVVIFFITLGML 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  175 FLAGMSWRLIGLAVLLVAafIPVLWFFLMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLSGKGWLHGTQsQLE 254
Cdd:TIGR02614 171 FLAGAPLRYFALLLLLGL--LGGAILIVSSPYRMRRILSFLDPWADPFGSGYQLTQSLIALGSGGLFGVGLGNSVQ-KLF 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  255 FLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLILFVYVFVNIGMVSGILPVVGV 334
Cdd:TIGR02614 248 YLPEAHTDFIFAVIGEELGFIGVLIVILLFAFLVWRGLRIALRAEDLFGRYLAAGITIWIGLQAFINIGVVLGLLPTKGL 327
                         330       340
                  ....*....|....*....|....*....
gi 502612500  335 PLPLVSYGGSALIVLMAGFGIVMSIHTHR 363
Cdd:TIGR02614 328 TLPFISYGGSSLVATMIAIGLLLNISRER 356
RodA_shape NF037961
rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE ...
53-359 1.00e-56

rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE superfamily. It has been reported that RodA proteins play important roles in maintaining cell shape and antibiotic resistance in bacteria.


Pssm-ID: 411566  Cd Length: 415  Bit Score: 190.50  E-value: 1.00e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  53 IVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARF---IN 129
Cdd:NF037961  45 IGLSFVLIILILAIEAKFYERFSSIIYIISLLSLLGLFIFGKTINGATSWYAIGGFTLQPSEFAKAATALALAKYlsdIQ 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 130 RDVcpPSLKHTGIALILIFLPTLLVAAQPDLGtSILVAASGLFILFLAGMSWRLIGLAVLLVAAFIPVLWF--------- 200
Cdd:NF037961 125 TDI--KRFKDQLKAFAIILIPAILILLQPDAG-SALVYFAFFFVLYREGLPLIYLIIGFILILLFVLTLKFgpiwvliia 201
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 201 ---FLMHDY-------------------------------------QRDRVMMLLDPESDPL-------GAGYHIIQSKI 233
Cdd:NF037961 202 allIFLYYFlkkkkkppilkiiiillicilfsfsvnfvydnvleqhHRDRFSLWLGLEKDPEkleqmkkTIGYNTNQSEK 281
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 234 AIGSGGLSGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLFGVLLLLALYLLIIMRGLYIAARAQTTFGRVMVGGLMLI 313
Cdd:NF037961 282 AISSGGFTGKGFLEGTRTKGNFVPEQHTDYIFSTVGEEWGFLGSSLVVLLFVLLLLRIIYLAERQKSQFSRVYGYSVASI 361
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 502612500 314 LFVYVFVNIGMVSGILPVVGVPLPLVSYGGSALIvlmaGFGIVMSI 359
Cdd:NF037961 362 LFIHFFINIGMVIGLIPTIGIPLPFFSYGGSGLW----GFTILLFI 403
PRK10774 PRK10774
cell division protein FtsW; Provisional
53-359 3.78e-41

cell division protein FtsW; Provisional


Pssm-ID: 182719  Cd Length: 404  Bit Score: 149.16  E-value: 3.78e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500  53 IVMGLLVMIVMAQIPPRVYEHWAPYLYILCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAVPLMVARFINRDV 132
Cdd:PRK10774  79 LILAFGLALITLRLPMEFWQRYSATMLLGSIIMLLIVLVVGSSVNGASRWIALGPLRIQPAELTKLSLFCYLANYLVRKV 158
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 133 ----------CPPslkhTGIALILiflpTLLVAAQPDLGTSILVAASGLFILFLAGMS-WRLigLAVLLVAAFIPVLwFF 201
Cdd:PRK10774 159 devrnnfwgfLKP----MGVMLVL----AVLLLAQPDLGTVVVLFVTTLAMLFLAGAKlWQF--IAIIGMGISAVVL-LI 227
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 202 LMHDYQRDRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLSGKGWLHGTQsQLEFLPERHTDFIFAVLAEELGLFGVLLLL 281
Cdd:PRK10774 228 LAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQ-KLEYLPEAHTDFIFSIIGEELGYIGVVLAL 306
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502612500 282 ALYLLIIMRGLYIAARA---QTTFGRVMVGGLMLILFVYVFVNIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMS 358
Cdd:PRK10774 307 LMVFFVAFRAMSIGRKAleiDQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLR 386

                 .
gi 502612500 359 I 359
Cdd:PRK10774 387 I 387
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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