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Conserved domains on  [gi|502309770|ref|WP_012759397|]
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ABC transporter permease [Rhizobium leguminosarum]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 18-287 8.18e-119

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 341.71  E-value: 8.18e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  18 SRAWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAG 97
Cdd:COG1173    6 RRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  98 VFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVL 177
Cdd:COG1173   86 LLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 178 SVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQA 257
Cdd:COG1173  166 SLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTA 245

                        250       260       270
                 ....*....|....*....|....*....|
gi 502309770 258 PWMAMWPGAAIFLVVIGFNLLGDGLRDALD 287
Cdd:COG1173  246 PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 18-287 8.18e-119

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 341.71  E-value: 8.18e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  18 SRAWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAG 97
Cdd:COG1173    6 RRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  98 VFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVL 177
Cdd:COG1173   86 LLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 178 SVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQA 257
Cdd:COG1173  166 SLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTA 245

                        250       260       270
                 ....*....|....*....|....*....|
gi 502309770 258 PWMAMWPGAAIFLVVIGFNLLGDGLRDALD 287
Cdd:COG1173  246 PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 1-289 1.72e-81

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 248.10  E-value: 1.72e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770   1 MTAIGETVIPSAIDRSPSRAWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDP-NATSWSAIRKAPSAAHWLGTDDIG 79
Cdd:PRK15082   9 VLNAMPLVKPDQVRTPWHEFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYDAeNYFDYDALNAGPSLQHWFGVDSLG 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  80 RDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIA 159
Cdd:PRK15082  89 RDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 160 IGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPP 239
Cdd:PRK15082 169 VAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPP 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 502309770 240 APSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:PRK15082 249 TPEWGAMLNEARADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPK 298
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 54-287 3.72e-74

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 227.65  E-value: 3.72e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770   54 DPNATSWSAIRKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAF 133
Cdd:TIGR02790  25 DPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLAGYIGGRVDEAIMRVCDVF 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  134 LAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILV 213
Cdd:TIGR02790 105 LSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASHWQIIRRHILPNILSPIIV 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502309770  214 QATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALD 287
Cdd:TIGR02790 185 LATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAFNLLGDALRDHLG 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-275 9.38e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 79.24  E-value: 9.38e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  93 SLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLG--------PSLTNAMIAIGLSA 164
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilPGLGLPALILALLL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 165 MPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGqQPPAPSWG 244
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPGTG 162

                        170       180       190
                 ....*....|....*....|....*....|.
gi 502309770 245 SMLNVAKNFLSQAPWMAMwpgAAIFLVVIGF 275
Cdd:cd06261  163 LLLIFAILFPGDLGVAAA---VALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-289 2.26e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 75.41  E-value: 2.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  108 GVPFGLISG-YFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPS----LTNAMIAIGLSAMPVFVRLTRGQVLSVKIE 182
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  183 EYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFL----GLGQQPPAPSWGSMLNvaknflsqap 258
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP---------- 150

                         170       180       190
                  ....*....|....*....|....*....|.
gi 502309770  259 wMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDPR 180
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 18-287 8.18e-119

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 341.71  E-value: 8.18e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  18 SRAWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAG 97
Cdd:COG1173    6 RRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  98 VFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVL 177
Cdd:COG1173   86 LLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 178 SVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQA 257
Cdd:COG1173  166 SLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTA 245

                        250       260       270
                 ....*....|....*....|....*....|
gi 502309770 258 PWMAMWPGAAIFLVVIGFNLLGDGLRDALD 287
Cdd:COG1173  246 PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 1-289 1.72e-81

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 248.10  E-value: 1.72e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770   1 MTAIGETVIPSAIDRSPSRAWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDP-NATSWSAIRKAPSAAHWLGTDDIG 79
Cdd:PRK15082   9 VLNAMPLVKPDQVRTPWHEFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYDAeNYFDYDALNAGPSLQHWFGVDSLG 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  80 RDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIA 159
Cdd:PRK15082  89 RDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 160 IGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPP 239
Cdd:PRK15082 169 VAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPP 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 502309770 240 APSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:PRK15082 249 TPEWGAMLNEARADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPK 298
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
1-289 8.47e-78

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 238.56  E-value: 8.47e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770   1 MTAIGETVIPSAIDRS----PSRAWRkLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAPSAAHWLGTD 76
Cdd:PRK09881   1 MMLSEETSAVRPQKQTrfngAKLVWM-LKGSPLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  77 DIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNA 156
Cdd:PRK09881  80 EVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 157 MIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQ 236
Cdd:PRK09881 160 MLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGA 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 502309770 237 QPPAPSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:PRK09881 240 QQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAVGFNLFGDGIRDLLDPK 292
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 54-287 3.72e-74

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 227.65  E-value: 3.72e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770   54 DPNATSWSAIRKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAF 133
Cdd:TIGR02790  25 DPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLAGYIGGRVDEAIMRVCDVF 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  134 LAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILV 213
Cdd:TIGR02790 105 LSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASHWQIIRRHILPNILSPIIV 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502309770  214 QATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALD 287
Cdd:TIGR02790 185 LATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAFNLLGDALRDHLG 258
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
21-289 6.73e-70

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 218.50  E-value: 6.73e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  21 WRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAP------SAAHWLGTDDIGRDILSRMIWGAQASL 94
Cdd:PRK10913  23 WHYFKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPvwqeggSWAHILGTDDVGRDVLSRLMYGARLSL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  95 MAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRG 174
Cdd:PRK10913 103 LVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRA 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 175 QVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFL 254
Cdd:PRK10913 183 AVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFA 262

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 502309770 255 SQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:PRK10913 263 QSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPK 297
nikC PRK10417
nickel transporter permease NikC; Provisional
 54-288 3.56e-65

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 205.29  E-value: 3.56e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  54 DPNATSWSAIRKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAF 133
Cdd:PRK10417  30 DPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADMF 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 134 LAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILV 213
Cdd:PRK10417 110 MTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLV 189

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 502309770 214 QATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDP 288
Cdd:PRK10417 190 LATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGLALFISVMAFNLLGDALRDHLDP 264
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
6-289 8.29e-57

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 184.63  E-value: 8.29e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770   6 ETVIPSAIdrspSRAWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAPS------AAHWLGTDDIG 79
Cdd:COG4171    9 EERIPSPL----KQIWQSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSPDQQFIGALLLPPSwddngdVSFFLGTDDLG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  80 RDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIA 159
Cdd:COG4171   85 RDILSRLLYGARYTFGSALLVVLAAAIIGGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 160 IGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPP 239
Cdd:COG4171  165 ITLALLPQFIHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLP 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 502309770 240 APSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:COG4171  245 SPEWGAMLGDSLELIYLAPWTVILPGLAIMFSVLIVNLVGDGLRRALNKG 294
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 20-290 1.10e-56

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 184.65  E-value: 1.10e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  20 AWRKLKANKGALVGLAIIAFFAILAIAAPLLPIPDPNATSWSAIRKAP--SAAHWLGTDDIGRDILSRMIWGAQASLMAG 97
Cdd:PRK15406  29 ARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPdmESGHYFGTDSSGRDLLVRVAIGGRISLMVG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  98 VFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVL 177
Cdd:PRK15406 109 VAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTL 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 178 SVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQA 257
Cdd:PRK15406 189 SLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVS 268

                        250       260       270
                 ....*....|....*....|....*....|...
gi 502309770 258 PWMAMWPGAAIFLVVIGFNLLGDGLRDALDPRE 290
Cdd:PRK15406 269 PWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKD 301
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 66-289 1.45e-52

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 174.95  E-value: 1.45e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  66 APSAAHWLGTDDIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIAL 145
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIIL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 146 AAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIA 225
Cdd:COG4239  196 SSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFLPFILSGAITT 275

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502309770 226 EASLSFLGLGQQPPAPSWGSMLNVAKNFLsQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:COG4239  276 LTSLDFLGFGLPPGSPSLGELLAQGKNNL-QAPWLGLSAFVVLALMLSLLVFIGEAVRDAFDPR 338
PRK15111 PRK15111
peptide ABC transporter permease SapC;
59-287 3.16e-42

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 146.77  E-value: 3.16e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  59 SWSairKAPSAAHWLGTDDIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPF 138
Cdd:PRK15111  67 SWS---RYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPS 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 139 LITAIALAAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLT 218
Cdd:PRK15111 144 LLLAIIVVAFAGPSLSHAMFAVWLALLPRMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRA 223

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502309770 219 IATAIIAEASLSFLGLGQQPPAPSWGSMLNVAKNFLSQAPWMAMWPGAAIFLVVIGFNLLGDGLRDALD 287
Cdd:PRK15111 224 LSMAILDIAALGFLDLGAQLPSPEWGAMLGDSLELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAII 292
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 66-291 1.83e-33

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 125.10  E-value: 1.83e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  66 APSAAHWLGTDDIGRDILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIAL 145
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 146 AAFLGPSLTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIA 225
Cdd:PRK15021 196 SSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITT 275

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502309770 226 EASLSFLGLGQQPPAPSWGSMLNVAKNFLsQAPWMAMwpgAAIFLVVIGFNLL---GDGLRDALDPREA 291
Cdd:PRK15021 276 LTSLDFLGFGLPLGSPSLGELLLQGKNNL-QAPWLGI---TAFLSVAILLSLLifiGEAVRDAFDPNKA 340
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-275 9.38e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 79.24  E-value: 9.38e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  93 SLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLITAIALAAFLG--------PSLTNAMIAIGLSA 164
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilPGLGLPALILALLL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 165 MPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFLGLGqQPPAPSWG 244
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPGTG 162

                        170       180       190
                 ....*....|....*....|....*....|.
gi 502309770 245 SMLNVAKNFLSQAPWMAMwpgAAIFLVVIGF 275
Cdd:cd06261  163 LLLIFAILFPGDLGVAAA---VALILLLLSL 190
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 77-236 1.53e-16

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 78.19  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  77 DIGRDILSRMIWgaqaSLMAGVFSVAIAVVIGVPFGLISGYF-GGWIDMVISRITEAFLAMPFLITAIAL---------- 145
Cdd:COG0601   86 PVSDLIAERLPV----TLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPSFWLGLLLillfavklgw 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 146 ---------AAFLGPSLTNA---MIAIGLSAMPVFVRLTRGQVLSVKIEEYVEGARSIGLRSSSIITRYILPNVFAPILV 213
Cdd:COG0601  162 lpvsgrvspWEDFLDALRHLilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        170       180
                 ....*....|....*....|....*..
gi 502309770 214 QATLTIAT----AIIAEASLSFLGLGQ 236
Cdd:COG0601  242 VLGLQLGGllggAVVVETVFSWPGLGR 268
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-289 2.26e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 75.41  E-value: 2.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  108 GVPFGLISG-YFGGWIDMVISRITEAFLAMPFLITAIALAAFLGPS----LTNAMIAIGLSAMPVFVRLTRGQVLSVKIE 182
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  183 EYVEGARSIGLRSSSIITRYILPNVFAPILVQATLTIATAIIAEASLSFL----GLGQQPPAPSWGSMLNvaknflsqap 258
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP---------- 150

                         170       180       190
                  ....*....|....*....|....*....|.
gi 502309770  259 wMAMWPGAAIFLVVIGFNLLGDGLRDALDPR 289
Cdd:pfam00528 151 -EIQGPVLAAALILLLLNLLVDILQRLLDPR 180
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 86-235 2.39e-06

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 47.84  E-value: 2.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  86 MIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFgGWIDMVISRITEAFLAMPFLITAIALAAFLGPSLTNAMIAIGLSAM 165
Cdd:COG0600   59 LWEHLLASLLRVLLGFALAALLGVPLGLLLGLS-RLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAF 137

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502309770 166 PVFVRLTRGQVLSVKiEEYVEGARSIGLRSSSIITR----YILPNVFAPILVQATLTIATAIIAEASLSFLGLG 235
Cdd:COG0600  138 FPILLNTAAGVRSVD-PELLELARSLGASRWQILRKvvlpAALPYIFTGLRIALGLAWIGLVVAELLGASSGLG 210
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
60-223 1.05e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 40.53  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  60 WSAIRKAPSAAhwLGTDDIGRDILSRMIWGA-QASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPF 138
Cdd:COG1178  311 LWSLTKALDDN--LTLDNYRFVLLDPSLLRAlLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPG 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 139 LITAIAL----AAFLGPSLTNAMIAIGLS----AMPVFVRLTRGQVLSVKiEEYVEGARSIGLRSSSIITRYILPNVFAP 210
Cdd:COG1178  389 IVLGLGLlllfNRPLPLLLYGTLAILVLAyvvrFLPFALRSLEAALAQID-PSLEEAARSLGASPLRTLRRVTLPLLRPG 467

                        170
                 ....*....|...
gi 502309770 211 ILVQATLTIATAI 223
Cdd:COG1178  468 LLAAALLVFVTSM 480
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 81-212 1.76e-03

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 38.90  E-value: 1.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770  81 DILSRMIWGAQASLMAGVFSVAIAVVIGVPFGLISGYFGGWIDMVISRITEAFLAMPFLItaIALAAFLG--------PS 152
Cdd:COG0765   10 DYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLV--QLFFIYFGlpllgidlSP 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 502309770 153 LTNAMIAIGLSAMPVFVRLTRGQVLSVKIEEYvEGARSIGLRSSSIITRYILPNVFAPIL 212
Cdd:COG0765   88 FVAAVIALTLNSAAYLAEIVRAGIQSVPKGQW-EAARALGLSRWQTMRRIILPQALRIIL 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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